ライフサイエンスコーパス: transcriptional mechanism

1 ncreases NPC1 levels in cells through a post-transcriptional mechanism.

2 ed by low shear stress via a GATA4-dependent transcriptional mechanism.

3 ha/PPARbeta/delta-->Src kinase-->STAT1/STAT3 transcriptional mechanism.

4 re peripheral neurons by a constitutive post-transcriptional mechanism.

5 R heterodimer and its associated ligands and transcriptional mechanism.

6 ls human epidermal differentiation by a post-transcriptional mechanism.

7 plausibly mediated via an anti-inflammatory transcriptional mechanism.

8 r critical neurological processes via a post-transcriptional mechanism.

9 ced BACE1 elevation was the result of a post-transcriptional mechanism.

10 TORC2, decreases the expression of PTEN via transcriptional mechanism.

11 nducible factor-1alpha (HIF-1alpha)-mediated transcriptional mechanism.

12 ng the AUG proximity effect as an underlying transcriptional mechanism.

13 creased the expression of CD44 protein via a transcriptional mechanism.

14 lear run-on sequencing were used to define a transcriptional mechanism.

15 ces ZTL and GI protein levels through a post-transcriptional mechanism.

16 , first by a post-transcriptional, then by a transcriptional mechanism.

17 t phases of the day and may depend on a post-transcriptional mechanism.

18 r proximal RNAPII pausing is a rate-limiting transcriptional mechanism.

19 a variety of physiological, biochemical, and transcriptional mechanisms.

20 usands of maternal mRNAs are cleared by post-transcriptional mechanisms.

21 ession through both transcriptional and post-transcriptional mechanisms.

22 n of DNMT1 and DNMT3a through different post-transcriptional mechanisms.

23 xpression via Sp1 and CREB protein-dependent transcriptional mechanisms.

24 of Plasmodium's genome is controlled by post-transcriptional mechanisms.

25 encing through both transcriptional and post-transcriptional mechanisms.

26 htly coordinated by transcriptional and post-transcriptional mechanisms.

27 is changed through transcriptional and post-transcriptional mechanisms.

28 ted coordination of transcriptional and post-transcriptional mechanisms.

29 d development are inhibited through distinct transcriptional mechanisms.

30 sphorylation and inhibition of JNK-regulated transcriptional mechanisms.

31 pal neurons by both transcriptional and post-transcriptional mechanisms.

32 ty structures through either localization or transcriptional mechanisms.

33 ed siRNAs, which likely silence TEs via post-transcriptional mechanisms.

34 in kinase-dependent transcriptional and post-transcriptional mechanisms.

35 ring inflammation are in part caused by post-transcriptional mechanisms.

36 2B drives tumorigenicity through 2 different transcriptional mechanisms.

37 anscription initiation and makes use of post-transcriptional mechanisms.

38 th a major shift towards epigenetic and post-transcriptional mechanisms.

39 unanswered regarding the involvement of post-transcriptional mechanisms.

40 ng rate homeostasis can be controlled by non-transcriptional mechanisms.

41 ightly co-ordinated transcriptional and post-transcriptional mechanisms.

42 drugs, through both transcriptional and non-transcriptional mechanisms.

43 ls are more sensitive to inhibition of these transcriptional mechanisms.

44 enewal through both transcriptional and post-transcriptional mechanisms.

45 nt on germline nuclear RNAi factors and post-transcriptional mechanisms.

46 In leu2Delta cells, transcriptional mechanisms also led to dramatic up-regul

47 rown adipocytes to environmental warmth, its transcriptional mechanisms and functional importance are

48 e mouse mammary tumor virus promoter through transcriptional mechanisms and impair the ability of the

49 The transcriptional mechanisms and pathway-specific inputs t

50 iments are critical for the investigation of transcriptional mechanisms and regulatory networks.

51 ient nature of GATA2 deficiency and identify transcriptional mechanisms and targets that lead to Mono

52 ing Wnt signaling by posttranscriptional and transcriptional mechanisms and that adenomatous polyposi

53 rate of internalization and translational or transcriptional mechanisms and that the cytoplasmic doma

54 tion has expanded our understanding of basic transcriptional mechanisms and their regulation and prov

55 mitochondrial densities, yet the underlying transcriptional mechanisms and time course are poorly un

56 does not upregulate GLT-1 and xCT through a transcriptional mechanism, and their coregulation by cef

57 c1 expression, increased Nfatc2 mRNA by post-transcriptional mechanisms, and had no effect on NFATc3

58 s insight into fundamental developmental and transcriptional mechanisms, and highlights mechanistic p

59 However, it remains possible that post-transcriptional mechanisms are also involved in controll

60 nctions in parallel with, cell type-specific transcriptional mechanisms are in their infancy.

61 Here we show that non-transcriptional mechanisms are sufficient to sustain cir

62 different extents in somatic cells, but the transcriptional mechanisms are unclear.

63 these altered protein levels are due to post-transcriptional mechanisms as the corresponding mRNA lev

64 ferentiation-specific keratins involves post-transcriptional mechanisms as we show KRT2 mRNA is stabi

65 Fezf2 and Aire utilized completely distinct transcriptional mechanisms, both of which were under the

66 ne (A-to-I) RNA editing is a widespread post-transcriptional mechanism, but its genomic landscape and

67 promote rapid spine formation through a non-transcriptional mechanism by means of the LIM kinase-cof

68 In this study, the novel transcriptional mechanism by which carrageenan and decli

69 mediator of autophagy and demonstrate a new transcriptional mechanism by which Smad2 inhibits angiog

70 protein and mRNA levels and show a detailed transcriptional mechanism by which this occurs.

71 The transcriptional mechanisms by which dorsal interneurons

72 We examined the electrophysiological and transcriptional mechanisms by which KCa3.1 regulates vas

73 The transcriptional mechanisms by which temporary exposure t

74 The precise transcriptional mechanisms by which these factors functi

75 However, the transcriptional mechanisms by which this occurs have not

76 increased RGS2 protein levels through a post-transcriptional mechanism, by slowing protein degradatio

77 Developing insight into tissue-specific transcriptional mechanisms can help improve our understa

78 ins unclear how the transcriptional and post-transcriptional mechanisms collectively control rhythmic

79 tissue-specific imprinting patterns and how transcriptional mechanisms compete to maximize the expre

80 e and inflammatory tissue MF pools and which transcriptional mechanisms contribute to these processes

81 The post-transcriptional mechanisms contributing to molecular reg

82 ill largely unknown transcriptional and post-transcriptional mechanisms control ISC distribution betw

83 In this study, we investigated the transcriptional mechanisms controlled by the Shox2 trans

84 al stem/progenitor cell (NSPC) fate, yet the transcriptional mechanism controlling Notch1 specific ex

85 ncer patients, little is known regarding the transcriptional mechanisms controlling recruitment of ma

86 In this review, we examine the transcriptional mechanisms controlling the development o

87 Previously, we reported that a transcriptional mechanism controls LPA-induced expressio

88 The transcriptional mechanism described here is rapidly reve

89 nstrate that in addition to previously known transcriptional mechanisms, differences in Drosha levels

90 The transcriptional mechanisms driving lineage specification

91 Unlike the genomic transcriptional mechanism employed by mSlo1, hSlo1 exhib

92 Here, we have investigated the complex transcriptional mechanisms employed by cardiomyocytes to

93 Here, we discuss how post-transcriptional mechanisms enable stem cell homeostasis

94 We discuss the biochemical and transcriptional mechanisms enabling these metabolites to

95 -dependent promoter activity as well as post-transcriptional mechanisms ensure the appropriate regula

96 ne-to-Inosine (A-to-I) RNA editing is a post-transcriptional mechanism, evolved to diversify the tran

97 Together, our data illuminate a key transcriptional mechanism for expression of the gene enc

98 This work has revealed a transcriptional mechanism for modulating the sensitivity

99 As a underlying transcriptional mechanism for neural fate determination,

100 This novel post-transcriptional mechanism for regulating hASH1 levels wi

101 on of LUX expression, thereby defining a new transcriptional mechanism for temperature input to the c

102 However, the post-transcriptional mechanism for the development of the rhi

103 In this study, we investigated transcriptional mechanisms for rapid IFN-gamma productio

104 lpha regulation and provide insight into non-transcriptional mechanisms for shaping cytokine response

105 Our results highlight the importance of non-transcriptional mechanisms for the maintenance of NSC qu

106 ment, and in this report, we demonstrate new transcriptional mechanisms for these factors.

107 Motif 1 potentially directs a distinct transcriptional mechanism from the canonical TATA box, w

108 ell mass, and a greater understanding of the transcriptional mechanisms governing beta-cell function

109 The diverse transcriptional mechanisms governing cellular differenti

110 By contrast to extensively studied transcriptional mechanisms governing differentiation, ma

111 Transcriptional mechanisms governing hematopoietic stem

112 of rodent and human adipocytes; however, the transcriptional mechanisms governing this phenotypic swi

113 f secreted progranulin levels through a post-transcriptional mechanism has recently been reported, th

114 RNA editing, a widespread post-transcriptional mechanism, has emerged as a new player i

115 Several transcriptional and post-transcriptional mechanisms have been shown to regulate K

116 A number of signaling and transcriptional mechanisms have been studied in relation

117 Although transcriptional mechanisms have been well documented in

118 Post-transcriptional mechanisms have the potential to influen

119 l conformations emerges as a novel layer for transcriptional mechanisms impacting neuronal signaling

120 These findings reveal a novel transcriptional mechanism in PFC that controls behaviora

121 contributes to stress responses through non-transcriptional mechanisms in addition to its well-estab

122 ) have been identified, but the role of post-transcriptional mechanisms in ASD is not well understood

123 ings demonstrate the involvement of distinct transcriptional mechanisms in mediating DeltaFosB induct

124 dy of literature implicating gene length and transcriptional mechanisms in neurodevelopmental and neu

125 ir receptors are potently regulated via post-transcriptional mechanisms in response to various stimul

126 Non-transcriptional mechanisms in the clockwork have been di

127 ble stress traits in twin pairs, established transcriptional mechanisms in transfected chromaffin cel

128 ression through posttranscriptional, but not transcriptional, mechanisms in astroglia.

129 In this review, we will focus on post-transcriptional mechanisms including noncoding RNAs, RNA

130 lt function through transcriptional and post-transcriptional mechanisms, including alternative splici

131 However, the details of what transcriptional mechanisms induce microglia to take bene

132 s compared to healthy controls, suggesting a transcriptional mechanism involved in reduced DMD transc

133 he first time in yeast, a nutrient-dependent transcriptional mechanism involved in the regulation of

134 ote NSC quiescence have been identified, the transcriptional mechanisms involved are mostly unknown,

135 However, the signaling pathways and the transcriptional mechanisms involved are not completely e

136 Collectively, these findings define transcriptional mechanisms involved in normal tooth deve

137 liferation, and shed light on the underlying transcriptional mechanisms involved.

138 dies reveal an evolutionarily conserved post-transcriptional mechanism involving competitive interact

139 oted VEGF expression and secretion through a transcriptional mechanism involving STAT3 and SP4.

140 thway and increase spine elimination through transcriptional mechanisms involving mineralocorticoid r

141 or Rox1 is compromised, cells activate post-transcriptional mechanisms, involving the exoribonucleas

142 ests that dysregulation of hypoxia-regulated transcriptional mechanisms is involved in development of

143 d model of AChR regulation, which implicates transcriptional mechanisms, it remains plausible that su

144 egulator of insulin signaling, and through a transcriptional mechanism leading to increase in GRB10 e

145 n through transcription factor networks, the transcriptional mechanisms leading to subtypes of the di

146 Post-transcriptional mechanisms likely make important contrib

147 These transcriptional mechanisms may contribute to other devel

148 Taken together, these data suggest that post-transcriptional mechanisms may contribute to stabilizati

149 ine (A-to-I) RNA editing is a conserved post-transcriptional mechanism mediated by ADAR enzymes that

150 Besides the classic transcriptional mechanism mediated by hormones, posttran

151 In the present study, we identified a post-transcriptional mechanism mediated by miR-34c-5p that go

152 ression of claudin-14 is regulated through a transcriptional mechanism mediated by NFATc1-microRNA an

153 Transcriptional mechanisms mediated by the binding of tr

154 The control of HilD by Pat was through post-transcriptional mechanisms, moderately repressing hilD t

155 Because post-transcriptional mechanisms modulate levels of p16 (encod

156 These results define a novel transcriptional mechanism of autoregulated homeostasis o

157 A) mRNA modification is as an important post-transcriptional mechanism of gene regulation(2-4) and ha

158 sed in cells treated with CyPB, suggesting a transcriptional mechanism of inhibition.

159 ) in clinical samples and PDXs, indicating a transcriptional mechanism of regulation.

160 els, and experimentally validate a novel non-transcriptional mechanism of relative sensing in mammali

161 noprecipitation was employed to identify the transcriptional mechanism of repressed HCN1 expression,

162 However, the transcriptional mechanism of S6K1 overexpression is not

163 ) interaction that strives to understand the transcriptional mechanism of the bEBPs, which probably i

164 Our finding reveals a new post-transcriptional mechanism of TMPRSS2-ERG regulation by S

165 ole for Ski-Satb2 interactions in regulating transcriptional mechanisms of callosal neuron specificat

166 The emerging transcriptional mechanisms of CEBPA are discussed based

167 l of this study is to identify novel cardiac transcriptional mechanisms of coronary angiogenesis and

168 To investigate the epigenetic and transcriptional mechanisms of coronary artery disease (C

169 is study, we used RNA sequencing to quantify transcriptional mechanisms of extreme dehydration tolera

170 neuronal conversion of astrocytes to dissect transcriptional mechanisms of fate determination and ide

171 tudies and utilize our method to investigate transcriptional mechanisms of fibroblast phenotypic plas

172 regulator, improves our understanding of the transcriptional mechanisms of nuclear control over mitoc

173 depression and understanding the relation to transcriptional mechanisms of susceptibility and natural

174 NMs on human health by contextualizing their transcriptional mechanism-of-action with respect to drug

175 mostly regulate gene expression through post-transcriptional mechanisms, particularly mRNA stability.

176 Such suppression transpires through a transcriptional mechanism, predominantly at the proximal

177 Our results suggest that several post-transcriptional mechanisms regulate Rbp35/CfI25 complex

178 Post-transcriptional mechanisms regulate the stability and, h

179 ent to induce lung adenocarcinomas; however, transcriptional mechanisms regulated by K-Ras during the

180 Yet, the underlying transcriptional mechanisms regulating CD8(+) T cell exha

181 Post-transcriptional mechanisms regulating cell surface synap

182 To identify transcriptional mechanisms regulating differentiation an

183 Several transcriptional mechanisms regulating expression of PTF1

184 Here, we have asked about post-transcriptional mechanisms regulating murine development

185 (lncRNAs) represent an integral part of the transcriptional mechanisms regulating pancreas developme

186 We demonstrate new transcriptional mechanisms regulating signaling centers

187 ese results advance our understanding of the transcriptional mechanisms regulating signaling pathways

188 ys, biochemistry and genetics to dissect the transcriptional mechanisms regulating SOP-specific rhomb

189 s) promote tumor malignancy, but the precise transcriptional mechanisms regulating the acquisition of

190 unctional repertoire of PRDMs as well as the transcriptional mechanisms regulating translation.

191 Transcriptional mechanisms regulating type I collagen ge

192 lity to induce apoptosis, but the underlying transcriptional mechanisms remain poorly defined.

193 ed extensively, the underlying intracellular transcriptional mechanisms remain poorly understood.

194 This finding provides insights into transcriptional mechanisms required for normal and patho

195 We show that post-transcriptional mechanisms restrict miR-128 accumulation

196 f vascular homeostasis and inflammation, but transcriptional mechanisms specifying their identities a

197 ittle is known about how alterations in post-transcriptional mechanisms, such as mRNA turnover, contr

198 silences transcription, can proceed by a co-transcriptional mechanism that also promotes sRNA genera

199 These data establish a post-transcriptional mechanism that can fine-tune gene expres

200 RNA editing is a widespread post-transcriptional mechanism that can make a single base ch

201 poxia, and we may have revealed a novel post-transcriptional mechanism that controls c-Myc expression

202 These findings establish a post-transcriptional mechanism that controls CPSF6 expression

203 s provide the basis for an unrecognized post-transcriptional mechanism that functionally links expres

204 hat TGFbeta induces SIK1 levels via a direct transcriptional mechanism that implicates the Smad prote

205 r data indicate that ACK1 loss may be a post-transcriptional mechanism that increases EGFR signaling

206 lternative splicing represents a unique post-transcriptional mechanism that increases the complexity

207 vels of SR-B1 in Caco-2/TC7 cells via a post-transcriptional mechanism that involves microRNAs.

208 In this report, we outline the transcriptional mechanism that is defective in ARS.

209 oss occurs through a contact-dependent, post-transcriptional mechanism that is independent of the maj

210 uction of Survivin by IGF-I occurs through a transcriptional mechanism that is mediated in part by th

211 Our data reveal a post-transcriptional mechanism that maintains actin dynamics

212 This work identifies a novel transcriptional mechanism that mediates skeletal muscle

213 nosine (A-to-I) RNA editing is a co- or post-transcriptional mechanism that modifies genomically enco

214 In this study, we report a post-transcriptional mechanism that regulates CPSF6 via the c

215 Thus, we have uncovered a Pitx2-Sox2-Lef-1 transcriptional mechanism that regulates DESC homeostasi

216 e polyadenylation (APA) is a widespread post-transcriptional mechanism that regulates gene expression

217 Together, these data reveal a Foxp-based transcriptional mechanism that regulates the integrity a

218 Since the transcriptional mechanisms that are conserved in phage a

219 ession of imprinted genes and miRNAs through transcriptional mechanisms that are distinct from classi

220 l (EC) physiology during atherosclerosis via transcriptional mechanisms that are incompletely underst

221 e current study extends our understanding of transcriptional mechanisms that are operational in the p

222 In this study, we highlight novel post-transcriptional mechanisms that can modulate NLRP3 expre

223 hibit tumor growth in vivo However, the post-transcriptional mechanisms that cause miR-34a loss in ca

224 es are starting to provide insights into the transcriptional mechanisms that cause robust versus stoc

225 recent advances in our understanding of the transcriptional mechanisms that control brown and beige

226 We then focused on deciphering transcriptional mechanisms that control enhancer activit

227 requent regeneration failures in humans, the transcriptional mechanisms that control long-term surviv

228 MA is a key regulator of apoptosis, the post-transcriptional mechanisms that control PUMA protein sta

229 We explored transcriptional mechanisms that control the activity of

230 Transcriptional mechanisms that control the phenotypic c

231 However, the underlying transcriptional mechanisms that control their expression

232 ctor T cells, very little is known about the transcriptional mechanisms that dampen the glycolysis pr

233 However, the transcriptional mechanisms that determine the thermogeni

234 Altogether, we define unexpected post-transcriptional mechanisms that direct appropriate cell

235 Transcriptional mechanisms that drive angiogenesis and o

236 tion of LDLR is well characterized, the post-transcriptional mechanisms that govern LDLR expression a

237 nd lineage decisions of human HSCs, the post-transcriptional mechanisms that guide HSC fate have not

238 deeper and more precise understanding of the transcriptional mechanisms that induce and maintain the

239 tical role for sumoylation in regulating the transcriptional mechanisms that maintain the basal cance

240 We explored several possible post-transcriptional mechanisms that may contribute to the el

241 strategies to reveal the relevant regulatory transcriptional mechanisms that may underlie neuropsychi

242 Post-transcriptional mechanisms that modulate global and/or t

243 Little is known about the post-transcriptional mechanisms that modulate the genetic eff

244 e interplay between transcriptional and post-transcriptional mechanisms that normally control the exp

245 ere remains a lack of insight of the nuclear transcriptional mechanisms that occur within endothelial

246 Here we describe transcriptional mechanisms that pattern remodeling of C.

247 The transcriptional mechanisms that promote remodeling in ad

248 on of PDK4 triggers transcriptional and post-transcriptional mechanisms that re-program the heart for

249 mation, relatively little is known about the transcriptional mechanisms that regulate AV delay, the p

250 in this article we demonstrate several Sox2 transcriptional mechanisms that regulate dental stem cel

251 lores the role of SUMOylation in controlling transcriptional mechanisms that regulate EMT/MET in canc

252 We present evidence for central transcriptional mechanisms that regulate fate specificat

253 However, the transcriptional mechanisms that regulate granulopoiesis

254 Although transcriptional mechanisms that regulate mitochondrial a

255 The transcriptional mechanisms that regulate striatal DARPP-

256 on androgen receptor (AR) signaling through transcriptional mechanisms that require interactions wit

257 Transcriptional mechanisms that restrict such a mild for

258 However, the transcriptional mechanisms that specify human microglia

259 for the first time that miR-296-5p inhibits transcriptional mechanisms that support GBM SCs and iden

260 This identification of transcriptional mechanisms that support long-term surviv

261 However, the intrinsic transcriptional mechanisms that temporally control diffe

262 g TGF-beta1, and requires p38alpha MAPK, but transcriptional mechanisms that underlie cytokine-driven

263 Understanding the transcriptional mechanisms that underlie pancreas format

264 Our findings provide a paradigm for transcriptional mechanisms that underlie the changes in

265 Transcriptional mechanisms that underlie the dose-depend

266 DNMT1 is regulated through at least two post-transcriptional mechanisms; that is, strong TCR signal i

267 Through this post-transcriptional mechanism, the 5'-UTR of the fimAICDHF t

268 offer molecular insights into the underlying transcriptional mechanism.The transcriptional co-activat

269 scussion of the current understanding of the transcriptional mechanisms they employ and consideration

270 y down-regulated by IGF1 signaling by a post-transcriptional mechanism through the MAPK pathway.

271 that has been made in elucidating eukaryotic transcriptional mechanisms through an array of disciplin

272 In other cases, SUMOylation alters transcriptional mechanisms through secondary effects.

273 Instead, it relies on a post-transcriptional mechanism to control its flagellar synth

274 RNA splicing represents a post-transcriptional mechanism to generate multiple functiona

275 on has been appreciated as an essential post-transcriptional mechanism to program local proteome comp

276 st that SAP1 is involved in a selective post-transcriptional mechanism to regulate the abundance of t

277 n-optimal codon usage was selected as a post-transcriptional mechanism to switch between circadian an

278 of immunometabolism, which engages distinct transcriptional mechanisms to coordinate the balance bet

279 ese polar arthropods have developed distinct transcriptional mechanisms to cope with similar desiccat

280 ghtly regulated via transcriptional and post-transcriptional mechanisms to rapidly induce genes that

281 , we show that yeast have developed multiple transcriptional mechanisms to regulate Ccc1 expression a

282 indicate that mammary tumors use potent post-transcriptional mechanisms to suppress Nrdp1 protein lev

283 protein receptor abundance by IDOL as a post-transcriptional mechanism underlying the structural and

284 ene expression changes in the brain, but the transcriptional mechanisms underlying memory impairments

285 e to exercise, but little is known about the transcriptional mechanisms underlying physiological hype

286 However, the transcriptional mechanisms underlying the cooperative ro

287 Transcriptional mechanisms underlying this cellular repr

288 and induces cell proliferation; however, the transcriptional mechanisms underlying this mitogenic rol

289 To decipher the transcriptional mechanisms upon which TAF4b functions in

290 that BBR induces TRIB1 mRNA expression by a transcriptional mechanism via ERK signaling pathway.

291 In exploring a transcriptional mechanism, we identify a novel c-maf (re

292 While loss of 15-PGDH can occur through transcriptional mechanisms, we demonstrate that 15-PGDH

293 oans, possess a distinctive feature in their transcriptional mechanism whereby a specific Spliced Lea

294 findings demonstrate for the first time the transcriptional mechanism whereby ARSB can regulate expr

295 Our results point toward a transcriptional mechanism whereby cocaine alters specifi

296 e, to our knowledge, of a tightly controlled transcriptional mechanism whereby IRF5 regulates proinfl

297 Our results suggest a novel, post-transcriptional mechanism whereby Th17 cytokines are inh

298 se isoforms arise predominantly from complex transcriptional mechanisms, which contribute to an incre

299 st a more general paradigm for Wnt-regulated transcriptional mechanisms, which is relevant for tissue

300 ons, in part through a ZFP36L2-mediated post-transcriptional mechanism, with consequences for axonal