ライフサイエンスコーパス: transcriptional start site

1 tween -79 and -60 base pairs upstream of the transcriptional start site.

2 GC-rich DNA sequence 264 bp upstream of the transcriptional start site.

3 24 LP sites of which ~50% were +/- 2 kb of a transcriptional start site.

4 ial methylation occurring within 2 kb of the transcriptional start site.

5 acetylation of histones upstream of the TLR9 transcriptional start site.

6 at the rpoS promoter overlaps the primary P1 transcriptional start site.

7 tes in the c-Myc locus upstream of the c-Myc transcriptional start site.

8 d on Gli binding to a site close to the ANO1 transcriptional start site.

9 g of acetylated histone H3K9 surrounding the transcriptional start site.

10 equence approximately 130 bp upstream of the transcriptional start site.

11 n RNA polymerase II recruitment to the PTPN1 transcriptional start site.

12 in a specific DNA motif upstream of the cagA transcriptional start site.

13 s that begin at canonical distances from the transcriptional start site.

14 gets an enhancer 10 kb upstream of the Il12b transcriptional start site.

15 ns beginning within 5 nt of the CMV promoter transcriptional start site.

16 of GATA motifs 2.8 kb upstream of the Gata2 transcriptional start site.

17 ed adjacent to one another downstream of the transcriptional start site.

18 ive enhancer (TonE) upstream of the rat Sgk1 transcriptional start site.

19 nd -24 and -12 nucleotides upstream from the transcriptional start site.

20 rich sequence approximately 1.5 kb from the transcriptional start site.

21 sites, at bases -708 and -75 upstream of the transcriptional start site.

22 the first intron and downstream of the IRS1 transcriptional start site.

23 Cik1 isoform is expressed from an alternate transcriptional start site.

24 sus site present at -114 to -119 bp from the transcriptional start site.

25 they may be located kilobases distal to the transcriptional start site.

26 th HIV-1 genomic sequences downstream of the transcriptional start site.

27 ors centered at position -54 relative to the transcriptional start site.

28 er is within 100 nucleotides upstream of its transcriptional start site.

29 approximately 2900 bp upstream of the PCDH15 transcriptional start site.

30 d upstream, the other downstream of the hlyE transcriptional start site.

31 ferentially at a site just downstream of the transcriptional start site.

32 proximately 1 kb downstream of the Inpp5f_v3 transcriptional start site.

33 between -533 bp and -332 bp upstream of the transcriptional start site.

34 erR binds to a region downstream of the P(3) transcriptional start site.

35 nse CpG island flanks the human HMW-MAA gene transcriptional start site.

36 s: -980, -745, -599 and -65, relative to the transcriptional start site.

37 Sp1 sites upstream of the exon 1A long MLCK transcriptional start site.

38 om 66 to 185 base pairs upstream of the algZ transcriptional start site.

39 RNAPII within transcribed regions toward the transcriptional start site.

40 on was mapped 2 kb upstream of the 12-HETER1 transcriptional start site.

41 proteins that bind remotely upstream of the transcriptional start site.

42 ausing inhibition of Pol II release from the transcriptional start site.

43 m regions of the FXN gene, involving the FXN transcriptional start site.

44 site was identified at -1 to +33, from tstR transcriptional start site.

45 stone H3, with increased accumulation around transcriptional start sites.

46 uce a global increase of the H3K4me3 mark at transcriptional start sites.

47 ng preferential binding to regions distal to transcriptional start sites.

48 and other nucleosomes at the early and late transcriptional start sites.

49 ed upstream and downstream, respectively, of transcriptional start sites.

50 ted genes, except for the 500 bp upstream of transcriptional start sites.

51 eukaryotic genes is aligned with respect to transcriptional start sites.

52 ies, but no overall changes were detected at transcriptional start sites.

53 itioned to alter the accessibility of select transcriptional start sites.

54 owed strong enrichment within exons and near transcriptional start sites.

55 eveals that it is predominantly localized to transcriptional start sites.

56 equences and the downstream -10 elements and transcriptional start sites.

57 68 binding sites immediately upstream of the transcriptional start sites.

58 A and 1B, which encode alternative long MLCK transcriptional start sites.

59 lated sequences that originate from distinct transcriptional start sites.

60 ire-containing complexes to local and distal transcriptional start sites.

61 agenize loci both upstream and downstream of transcriptional start sites.

62 in nucleosome-free regions proximal to their transcriptional start sites.

63 tic chromatin, are organized with respect to transcriptional start sites.

64 inding site and relate its location to known transcriptional start sites.

65 RNA polymerase II paused just downstream of transcriptional start sites.

66 etween nucleotides -8 and +2 relative to the transcriptional start site (+1) and has a consensus sequ

67 We identified 248 transcriptional start sites, 116 transcriptional termina

68 cer 32 kilobases (kb) downstream of the Irf8 transcriptional start site (+32-kb Irf8) that was active

69 IP-seq experiments show that OGA maps to the transcriptional start site/5' ends of genes, showing con

70 element located 489 bp upstream of the AQP2 transcriptional start site abolished the hypertonicity-i

71 eover, increased methylation of the IGF-1 P2 transcriptional start site among IUGR lineage F2 offspri

72 in addition to regulatory domains 5' of the transcriptional start site an important regulatory domai

73 te the expression of the expected genes, and transcriptional start site analysis has found that their

74 ), are located 1.4 kb upstream of the Cyp1a1 transcriptional start site and 12.6 kb upstream of the C

75 it plus approximately 7.4 kb upstream of the transcriptional start site and approximately 2 kb downst

76 interaction of NF-kappaB was observed at the transcriptional start site and at mRL-D5.

77 binds to KLF4 at multiple sites flanking the transcriptional start site and controls its expression.

78 Mutant p53 binds near the VEGFR2 promoter transcriptional start site and plays a role in maintaini

79 e selected genes had stalled Pol II at their transcriptional start site and showed enhanced ser2 phos

80 ls of both modifications around the Cga gene transcriptional start site and that JNK inhibition drama

81 synthetic lac operator sequence between the transcriptional start site and the ribosomal binding sit

82 murine osteosarcoma viral oncogene homolog) transcriptional start site and within the gene promoter

83 We identified 691 A. actinomycetemcomitans transcriptional start sites and 210 noncoding RNAs durin

84 controllers showed an increased distance to transcriptional start sites and accessible chromatin of

85 in structure: nucleosome-depleted regions at transcriptional start sites and conserved -1 and +1 prom

86 d origins identified by ini-seq are found at transcriptional start sites and contain G-quadruplex (G4

87 on of multiple isoforms that use alternative transcriptional start sites and different polyadenylatio

88 s6 correlates with nucleosome positioning at transcriptional start sites and expression levels of >1,

89 /miR-499 gene expression, we have mapped the transcriptional start sites and identified an upstream 6

90 correlate with genomic landmarks, including transcriptional start sites and intron-exon junctions.

91 We also identified transcriptional start sites and other putative regulator

92 nner, with poly(dA) tracts lying proximal to transcriptional start sites and poly(dT) tracts lying di

93 ug-selected cells is accompanied by multiple transcriptional start sites and predominance of the more

94 l analyses of the operon identified multiple transcriptional start sites and provided evidence for th

95 romoters, alternative splicing, and multiple transcriptional start sites and termination sites; while

96 e P. aeruginosa hcnA promoter contains three transcriptional start sites and that HCN production is r

97 ys-4-me3 signal, which was enriched near the transcriptional start sites and the coding regions.

98 oximity to or increased distance from active transcriptional start sites and to accessible chromatin

99 F3) at -258 to -250 base pairs from the HSF1 transcriptional start site, and electrophoretic mobility

100 ATT-box binding protein CEBPZ present at the transcriptional start site, and this is required for rec

101 nd a CCAAT box approximately 500 bp from the transcriptional start site, and to an AT rich sequence a

102 the location of DNaseI hypersensitive sites, transcriptional start sites, and active promoters.

103 e digestion landscape of protein-coding gene transcriptional start sites, and demonstrate a comparati

104 Alternative promoters, transcriptional start sites, and mRNA splicing lead to t

105 tributed both upstream and downstream of the transcriptional start sites, and that early transcriptio

106 I binding show peaks centered around cis-NAT transcriptional start sites, and the levels of activatin

107 eQTLs involving SNPs in promoter regions or transcriptional start sites; and 12 involving potential

108 ow distributions of these modifications near transcriptional start sites are associated with constitu

109 Transcriptional start sites are identified by analyzing

110 ich NFRs that extend downstream of annotated transcriptional start sites are nevertheless bound by no

111 transcript annotation and found that 35% of transcriptional start sites are supported by CAGE cluste

112 to be between -131 and +20 (using the distal transcriptional start site as +1).

113 Escherichia coli, with binding close to the transcriptional start site associated with repression an

114 ntified clusters of SNPs upstream of the Lxn transcriptional start site, at least two of which are as

115 dentified two novel ASVs from an alternative transcriptional start site (ATSS) of the MBP gene as wel

116 on of the previously reported nifH1 and vnfH transcriptional start sites by 5'RACE (5' rapid amplific

117 ty itself relies on alternative splicing and transcriptional start site choice to generate a full-len

118 negative tumors were clustered closer to the transcriptional start site compared with ER-positive tum

119 gene, one of which, located -22 kb from the transcriptional start site, contains clustered consensus

120 evels increased at the region closest to the transcriptional start site, correlating with a 40-60% de

121 Two cti transcriptional start sites (cti-279 and cti-77) were id

122 Annotation of 1625 transcriptional start sites defines transcription units

123 Identification of transcriptional start sites, demarcating overlapping gen

124 pends on transcriptional regulators and uses transcriptional start sites different from those used in

125 e Pfim3 promoter elements upstream of the +1 transcriptional start site do indeed direct Bvg-activate

126 macrophage-specific promoters lack classical transcriptional start site elements such as TATA boxes a

127 fails to stably propagate to and beyond the transcriptional start site even when the DNA template is

128 A transcriptional start site for a mucD promoter (PmucD) w

129 The transcriptional start site for covR was found to be 221

130 The transcriptional start site for each operon was determine

131 In the study presented here, the transcriptional start site for mntH in B. abortus 2308 w

132 on results from Zap1-mediated changes in the transcriptional start site for RTC4 and the production o

133 Examination of the 5' transcriptional start site for the sat mRNA revealed two

134 The transcriptional start site for vqsR was determined.

135 Transcriptional start sites for akinete-expressed genes

136 kinin with binding sites enriched toward the transcriptional start sites for both induced and repress

137 of the 5'RACE-PCR products revealed multiple transcriptional start sites for each variant, particular

138 The transcriptional start sites for the divergently oriented

139 id amplification of cDNA ends identified the transcriptional start sites for these operons and provid

140 tingly, exons corresponding to the alternate transcriptional start sites for tp53 and mdm2 were prefe

141 ing from an upstream promoter or by multiple transcriptional start sites from a downstream promoter.

142 We have mapped the transcriptional start sites from each promoter and exami

143 inserted between the promoter and the hCD39 transcriptional start site, generating a mouse in which

144 n of an ISSod1 element upstream of the sirCD transcriptional start site, generating a novel, constitu

145 mited region of the promoter surrounding the transcriptional start site has relatively high levels of

146 55 bp element, located 40 bp 5' of the Abd-B transcriptional start site, has a novel cis-regulatory a

147 Both major and minor transcriptional start sites have been identified, and th

148 We identified a C-to-T SNP upstream of the transcriptional start site in approximately 6% of the pe

149 ly(T)] tract -50 to -33 relative to the sabA transcriptional start site in H. pylori strain J99.

150 into the -1 nucleosome and does not bury its transcriptional start site in the +1 nucleosome.

151 ma variant induces a large distortion in the transcriptional start site in the absence of core RNA po

152 PKMzeta is generated via an alternative transcriptional start site in the atypical protein kinas

153 a distal enhancer at -6.4 kb relative to the transcriptional start site in the Pdx1 gene.

154 The transcriptional start sites in both the vah1-plp and rtx

155 creased H3K27 trimethylation (H3K27me3) near transcriptional start sites in genome-wide sequencing of

156 ind that H3K4me1 and H3K4me3 are enriched at transcriptional start sites in the genome of the develop

157 ase protection assays were used to determine transcriptional start sites in the microbisporicin gene

158 nowledege the first global annotation of the transcriptional start sites in V. cholerae and highlight

159 matin remodelers position nucleosomes around transcriptional start sites in yeast, and a few "locked"

160 located at -623 and +761 bp (relative to the transcriptional start site) in proximity to one another.

161 6 to -29 relative to the sigma(70)-dependent transcriptional start site) in the fliA promoter.

162 methylation and expression of an alternative transcriptional start site, including AKT3 The novel AKT

163 on from -6 to -10 kb with respect to the mpz transcriptional start site is dissociable from the cis-r

164 oter revealed that AP-1 site proximal to the transcriptional start site is required for 15(S)-HETE-in

165 E-1c promoter is highly polymorphic, harbors transcriptional start sites, is able to recruit the tran

166 ntiviruses and preferential integration near transcriptional start sites, like gammaretroviruses.

167 bbb22 was dependent on an additional distal transcriptional start site located within the bbb23 open

168 binding were remote from gene promoters and transcriptional start sites, located primarily in intron

169 We were also able to validate a number of transcriptional start sites, many of which were consiste

170 Our global transcriptional start site map represents a valuable res

171 Transcriptional start site mapping and promoter analysis

172 sites at 85, 289 and 345 bp upstream of the transcriptional start site mediated responses to RANKL a

173 protein-coding gene promoters, which we name transcriptional start site miRNAs (TSS-miRNAs).

174 , leading to clustered mutations near active transcriptional start sites; non-canonical AID (nc-AID),

175 A 5'-RACE study determined the transcriptional start site of AKR1B10 at 320 bp upstream

176 on a NF-kappaB-binding element close to the transcriptional start site of CCL20.

177 ruppel-like factor 2 (KLF2) binding near the transcriptional start site of CD39.

178 open chromatin region 6 kb downstream of the transcriptional start site of Cebpe in murine myeloid ce

179 e genomic sequence surrounding the predicted transcriptional start site of col2a1a among several spec

180 es demonstrate that BRD4 is recruited to the transcriptional start site of differentiation-induced ge

181 liary gene located in close proximity to the transcriptional start site of FTO) are regulated by isof

182 Primer extension located the transcriptional start site of hrpS at a sigma70 promoter

183 ntibody and PCR primers directed against the transcriptional start site of IL-6 and CXCL8 gene promot

184 rious cancers, and a CpG island spanning the transcriptional start site of LTF is hypermethylated in

185 score approximately -9400 bp upstream of the transcriptional start site of Nkx2-5, which overlapped w

186 Primer extension analysis identified the transcriptional start site of PrhuI within a putative Fu

187 Additionally, we mapped the transcriptional start site of qseA, leading to the ident

188 sponse elements located within 500 bp of the transcriptional start site of STIM1.

189 that they are physically associated with the transcriptional start site of target genes, irrespective

190 t this distal enhancer communicates with the transcriptional start site of the CA12 gene via intrachr

191 Here we report the identification of the transcriptional start site of the full-length K15 gene i

192 ylase 3-containing repression complex at the transcriptional start site of the GR gene.

193 iously identified CTCF binding site near the transcriptional start site of the hTERT gene.

194 of which was located 20.5 kb upstream of the transcriptional start site of the Kruppel-like transcrip

195 The transcriptional start site of the misRS operon was mappe

196 This region contained the transcriptional start site of the most highly expressed

197 The transcriptional start site of the ptx genes does not res

198 In addition, the transcriptional start site of the qseBC promoter respons

199 a 1-kb region upstream of and including the transcriptional start site of the SF2ASF gene and used i

200 rimer extension analysis determined that the transcriptional start site of the uspA2H gene was locate

201 fied in the 2000-bp sequence upstream of the transcriptional start site of TRPC6.

202 ntire locus of Ube3a and extended beyond the transcriptional start site of Ube3a.

203 We also identify a promoter of wbpM, map a transcriptional start site of wbpM, and show that mucoid

204 on within 146 bp immediately upstream of the transcriptional start site of zebrafish CTCF that is loc

205 D-associated susceptibility regions with the transcriptional start sites of 304 target genes.

206 cter crescentus microarray chip, we identify transcriptional start sites of 769 genes, 53 of which ar

207 rate that H3K64ac is enriched in vivo at the transcriptional start sites of active genes and it defin

208 cated in the tethering of Setd1 complexes to transcriptional start sites of active genes.

209 sociates with chromatin and localizes to the transcriptional start sites of active genes.

210 alteration of the chromatin landscape at the transcriptional start sites of B-cell- and T-cell-specif

211 The transcriptional start sites of both operons were mapped,

212 , a histone mark that is associated with the transcriptional start sites of expressed genes.

213 methylated adenine clusters surrounding the transcriptional start sites of expressed genes; its dist

214 ci which are highly enriched proximal to the transcriptional start sites of genes of diverse function

215 FOXP3 binds near transcriptional start sites of its target genes.

216 Kcr accumulates at transcriptional start sites of sex-linked genes activate

217 cells evidenced that PRDM11 associates with transcriptional start sites of target genes and regulate

218 To identify the transcriptional start sites of the neuronal channel SCN8

219 that a GPNA oligomer designed to bind to the transcriptional start-site of human E-cadherin gene indu

220 o their differential utilization of distinct transcriptional start sites on the Ralpha2 promoter.

221 PDX12 transcription reveals two alternative transcriptional start sites, one of which is exclusive t

222 letion mutants with endpoints 3' to the P(3) transcriptional start site (positions +5, +15, and +30)

223 .7 kb gene fragment spanning the human SPRY3 transcriptional start site recapitulates the endogenous

224 The H3K4me3 signal becomes confined to transcriptional-start-site regions in 2-cell embryos, co

225 apping of the hcnA promoter identified a new transcriptional start site required for HCN production.

226 -140 bp and -193 to -190 bp upstream of the transcriptional start site, respectively.

227 d the basal transcription machinery near the transcriptional start site, revealing a role for JARID1d

228 The two algR transcriptional start sites, RT1 and RT2, are directly r

229 frame based on the experimentally identified transcriptional start site shortens this hypothetical pr

230 uding transcription factor binding sites and transcriptional start sites, show topological relationsh

231 Transcriptional start sites tended to reside about one h

232 entified a region 1.1 kb upstream of the CK5 transcriptional start site that is necessary for P4 acti

233 teracted with a 15-bp region upstream of the transcriptional start site that shared no similarity to

234 ylation within a region 1-kb upstream of the transcriptional start site that were upregulated after t

235 d by L3MBTL2 and E2F6, preferentially around transcriptional start sites that exhibited little overla

236 5,768 and -6,030 base pairs (relative to the transcriptional start site) that exhibited Pdx1-responsi

237 strain-specific motif downstream of the cagA transcriptional start site (the +59 motif) is associated

238 ockdown is robust when targeted far from the transcriptional start site, thereby allowing high-resolu

239 lanking region of the SPAK gene contains two transcriptional start sites, three transcription factor

240 We have mapped the K15 transcriptional start site to a position 152 nucleotides

241 NA secondary structure upstream of the first transcriptional start site to modulate transcription.

242 screen that targets more than 10,000 lncRNA transcriptional start sites to identify noncoding loci t

243 curation processes and the incorporation of Transcriptional Start Site (TSS) annotations from RIKEN'

244 ' RACE analysis revealed the presence of the transcriptional start site (TSS) at 62 bp upstream of th

245 Rather, Nup153 binds around the transcriptional start site (TSS) of developmental genes

246 transcription factors within 1-50 kb of the transcriptional start site (TSS) of genes highly express

247 1.84kb, 3.97kb and 4.76kb upstream from the transcriptional start site (TSS) of the human NOX4 gene

248 ellular proteins binding specifically to the transcriptional start site (TSS) region.

249 of 81 Drosophila lines to measure changes in transcriptional start site (TSS) usage, identifying thou

250 rant enrichment of repressive H3K9me3 at the transcriptional start site (TSS) with methylation-associ

251 d within a median distance of 11 kb from the transcriptional start site (TSS), the nearest GR binding

252 g the position of genomic landmarks like the transcriptional start site (TSS).

253 f a CpG island located downstream from SALL4 transcriptional start site (TSS).

254 ite is in a CpG island downstream from EpCAM transcriptional start site (TSS).

255 rst class of TP53 binding events occurs near transcriptional start sites (TSS) and is defined by prev

256 hromatin states: four states span genes from transcriptional start sites (TSS) to termination sites a

257 optimizing library construction by analysing transcriptional start sites (TSS), CRISRPi identified 92

258 eq) revealed that Aire bound all Pol-II-rich transcriptional start sites (TSS), irrespective of its e

259 e, we describe the determination of two NOL7 transcriptional start sites (TSS), the cloning of its re

260 is due to genomic integration preferences in transcriptional start sites (TSS).

261 ngle mutations that either create or disrupt transcriptional start sites (TSS).

262 s, and an automated prediction algorithm for transcriptional start sites (TSS).

263 T change at the -6 position relative to the transcriptional start site Tssr 40273; a T at this posit

264 TEs are enriched distal from transcriptional start sites (TSSs) and their frequency d

265 rapid amplification of cDNA ends (RACE), two transcriptional start sites (TSSs) and two putative prom

266 roximately 152 bp, in fission yeast and that transcriptional start sites (TSSs) are associated with n

267 ound a progressive depletion of H2A.Z around transcriptional start sites (TSSs) during MYC-induced tr

268 the discovery of 48,718 human gene antisense transcriptional start sites (TSSs) within TE sequences.

269 ZF-TFs whose targets lie within 1 kb of the transcriptional start sites (TSSs), screened them for in

270 tive sites exhibit marked aggregation around transcriptional start sites (TSSs), though the majority

271 predominantly targets human genes near their transcriptional start sites (TSSs).

272 gher conservation and were located closer to transcriptional start sites (TSSs).

273 erved regulatory element upstream of DICER's transcriptional start site upon melanocyte differentiati

274 and bb0729 are co-transcribed from a single transcriptional start site upstream of the bb0729 coding

275 We describe the existence of multiple transcriptional start sites upstream of DAP10 exon 1 and

276 Heterogeneous transcriptional start site usage by HIV-1 produces 5'-ca

277 issues results in expression of five OATP2B1 transcriptional start site variants that use distinct fi

278 omic GATA sites, and closer occupancy to the transcriptional start site versus nondifferentially expr

279 n Sequencing analysis showed that the MITF-A transcriptional start site was highly enriched with H3K2

280 erified using reporter fusions, and the fliB transcriptional start site was identified by primer exte

281 The transcriptional start site was mapped.

282 gh a CpG island surrounding the promoter and transcriptional start site was observed in both genes im

283 d approximately 350 bp downstream of the dev transcriptional start site, was bound by LadA, a newly i

284 cation of complementary DNA ends (RACE), two transcriptional start sites were identified.

285 e promoter and for promoter opening near the transcriptional start site, whereas its pol III-specific

286 inding with Polycomb group (PcG) proteins at transcriptional start sites, whereas it activated a modu

287 occupancy assay, we found that the major FXN transcriptional start site, which is normally in a nucle

288 nse element located at -119 to -133 from the transcriptional start site, which is responsible for a l

289 es located ~60 nucleotides downstream of the transcriptional start site, while beta genes bore Pol II

290 B3 promoter at minus 980 base pairs from the transcriptional start site with transcriptional enhancin

291 ll-density QS-mutant strain identified 7,240 transcriptional start sites with approximately 47% initi

292 A methylation in different genomic contexts: transcriptional start sites with or without CpG islands,

293 te 1 (at about position -100 relative to the transcriptional start site) with negative regulation and

294 irst two exons, secretion signal peptide and transcriptional start site, with the neomycin gene.

295 of these sequences are located far from the transcriptional start sites, with their distribution str

296 d response element sequences proximal to the transcriptional start site within the IL-6 promoter.

297 e further defined the DNA-binding region and transcriptional start site within the phoA promoter.

298 essed as long and short isoforms from unique transcriptional start sites within a single gene.

299 esults illustrate how the use of alternative transcriptional start sites within an ion channel modula

300 ension analysis, we identified two potential transcriptional start sites within the regulatory region