ライフサイエンスコーパス: transcytosis

1 n, "cytonemes", filopodia, "argosomes", and "transcytosis".

2 rates of transcellular vesicular transport (transcytosis).

3 transcellularly released at the tissue side (transcytosis).

4 ion of the BBB via an endocytotic mechanism (transcytosis).

5 ic cleft to afferent synapses (transsynaptic transcytosis).

6 etention by shedding surface Tf during their transcytosis.

7 ins the ability to move from cell-to-cell by transcytosis.

8 impacts the capacity for TfR to mediate BBB transcytosis.

9 plicated as the "receptor" mediating albumin transcytosis.

10 ross the cell to the basolateral membrane by transcytosis.

11 port the first microtubule motor involved in transcytosis.

12 icant reduction in EBV apical to basolateral transcytosis.

13 st virus replication inside cells during IgA transcytosis.

14 factors that regulate apical-to-basolateral transcytosis.

15 rant endosomes, and defective exocytosis and transcytosis.

16 receptor-mediated endocytosis and subsequent transcytosis.

17 intestinal barrier through receptor-mediated transcytosis.

18 ulation of virus significantly reduced HIV-1 transcytosis.

19 of HIV-1 and assess antiviral Ab blockade of transcytosis.

20 ssue M cells were defective in microparticle transcytosis.

21 cal to the basolateral surface via vesicular transcytosis.

22 o the apical surface of epithelial cells via transcytosis.

23 c receptor-mediated to non-specific caveolar transcytosis.

24 after mannose 6-phosphate receptor-mediated transcytosis.

25 d BBB penetrations through receptor-mediated transcytosis.

26 e axonal transport, which is consistent with transcytosis.

27 a caveolin-1 and increased caveolae-mediated transcytosis.

28 no cross inhibition of membrane binding and transcytosis.

29 constituents, which are trafficked there by transcytosis.

30 apical recycling, and basolateral-to-apical transcytosis.

31 es its apical localization in MDCK cells via transcytosis.

32 tive sorting with a partner protein, and (c) transcytosis.

33 terminals, thus demonstrating transsynaptic transcytosis.

34 -1, to regulate both BMP-9 signaling and LDL transcytosis.

35 ltrates throughout the tumour tissue through transcytosis.

36 increased BBB permeability due to increased transcytosis.

37 barrier by virtue of tight junctions and low transcytosis.

38 the regulation of IgE synthesis and allergen transcytosis.

39 nctions or suppressing endothelial vesicular transcytosis.

40 protein Caveolin-1 and promoting endothelial transcytosis.

41 n and imparts asymmetry for pIgR binding and transcytosis.

42 in a reproducible decrease in FcRn-mediated transcytosis.

43 plicated in regulating basolateral to apical transcytosis.

44 horylated nephrin, and 4) attenuated albumin transcytosis.

45 n vivo with the involvement of FcRn-mediated transcytosis.

46 from lysosomal degradation and promotes LDL transcytosis.

47 able to neutralize HIV-1 and to block viral transcytosis.

48 lar permeability via mainly caveolar protein transcytosis.

49 This transcytosis accounted for approximately 10% of total al

50 onstrated a similar 20-fold enhanced rate of transcytosis across an in vitro BBB model compared with

51 via CAM-mediated endocytosis, trafficked by transcytosis across cell monolayers without disrupting t

52 Chemokine transcytosis across endothelial cells and presentation o

53 gG1, 2F5 IgA2 more efficiently blocked HIV-1 transcytosis across epithelial cells and CD4(+) cell inf

54 tion, prechallenge sera to enhance SIVmac251 transcytosis across epithelial cells was associated with

55 ostchallenge rectal secretions inhibited SIV transcytosis across epithelial cells.

56 CAM to lysosomes, yet prominent and specific transcytosis across epithelial monolayers.

57 d gp340 as an important facilitator of HIV-1 transcytosis across genital tract tissue.

58 bnAb, denoted VRC01-LS, displayed increased transcytosis across human FcRn-expressing cellular monol

59 We report an approach to study insulin transcytosis across individual, primary human adipose mi

60 this may occur because generally inefficient transcytosis across intact mucosal surfaces could be enh

61 erichia coli (EHEC) require toxin uptake and transcytosis across intestinal epithelial cells.

62 from milk to blood by apical-to-basolateral transcytosis across intestinal epithelial cells.

63 cRn binding, resulting in a reduction of IgG transcytosis across intestinal or placental epithelial c

64 s screened for binding, internalization, and transcytosis across iPSC-derived BMECs.

65 23D7 and 25A4 did, however, reduce ricin transcytosis across MDCK II cell monolayers, possibly by

66 omplexes were cleared from brain to blood by transcytosis across the BBB via the neonatal Fc receptor

67 Receptor-mediated transcytosis across the blood-brain barrier (BBB) may be

68 In vitro, we show glucosamine vesicle transcytosis across the blood-brain barrier with intact

69 eins and tissue remodeling subsequent to its transcytosis across the endothelial barrier.

70 ot polymeric IgM, 2F5 Abs also blocked HIV-1 transcytosis across the epithelium and, importantly, acr

71 lant lectin or a luteovirus coat protein for transcytosis across the gut epithelium, or via entomopat

72 ach the ocular surface via receptor-mediated transcytosis across the lacrimal gland (LG), which produ

73 ta brain capillary binding, endocytosis, and transcytosis across the mouse blood-brain barrier are su

74 below the mucosal epithelium, or through HIV transcytosis across the mucosal epithelium of a noninfec

75 tibody titers, this pattern suggested virion transcytosis across the surface.

76 dileucine residues conferring apical-lateral transcytosis act through a clathrin-dependent process an

77 r repeated rectal challenges had lower serum transcytosis activity than did 19 animals who subsequent

78 ver, the inefficient transport suggests that transcytosis alone would not engender a significant ther

79 ached to carrier molecules, through cells by transcytosis, along cell extensions, or in released memb

80 iga toxin macropinocytosis and transcellular transcytosis alters current ideas concerning mechanisms

81 with transferrin (Tf) for receptor mediated transcytosis and a cell penetrating peptide-penetratin (

82 nt to explain the reduced FcRn-mediated IgG2 transcytosis and accounts for the low maternal/fetal IgG

83 Thus, PICALM regulates Abeta BBB transcytosis and clearance, which has implications for A

84 Rab5 and Rab11, leading to Abeta endothelial transcytosis and clearance.

85 tly coupled to both increased (125)I-albumin transcytosis and decreased transendothelial electric res

86 r, a conserved protein complex that mediates transcytosis and endosome-to-Golgi protein trafficking,

87 rmation in CNS endothelial cells to suppress transcytosis and ensure BBB integrity.

88 e first evidence of vesicle-mediated insulin transcytosis and highlights that its initial uptake is c

89 In villus explants, IgG-virion transcytosis and macrophage uptake were blocked with try

90 We investigated whether transcytosis and paracellular leakage are co-regulated.

91 Our findings indicate that transcytosis and paracellular permeability are co-regula

92 ent pathways to the axon have been proposed: transcytosis and selective retrieval/retention.

93 haemolytica invades differentiated BBECs by transcytosis and subsequently undergoes rapid intracellu

94 rosses the blood-brain barrier by adsorptive transcytosis and that murine angiotensin-converting enzy

95 of hypothetical mechanisms, such as "planar transcytosis" and "restricted extracellular diffusion."

96 lls functioned in endocytosis, bidirectional transcytosis, and recycling of chicken FcY/IgY.

97 ctin during neutrophil rolling; in chemokine transcytosis; and by binding and presenting chemokines a

98 New features of transcytosis are elucidated, including transport involvi

99 , the mechanisms of albumin reabsorption and transcytosis are undergoing intense study.

100 Our results reveal regulated transcytosis as an unexpected mode of Trk trafficking th

101 ature vessel leakage occurs entirely through transcytosis, as specialized tight junctions are functio

102 In a transcytosis assay, human IgE or IgE-derived immune comp

103 We show in transcytosis assays that CD23a, but not CD23b, acts as a

104 use of HIV-infected cells in epithelial cell transcytosis assays, and cell-associated infection of mu

105 ular "hitchhiking" through receptor-mediated transcytosis at the blood-brain barrier is a CNS drug de

106 se findings underscore the potential role of transcytosis blockade in the prevention of HIV-1 transmi

107 ly more potent than dimeric IgA in effecting transcytosis blockade.

108 d heparan sulfate moieties in mediating this transcytosis but add gp340 as an important facilitator o

109 cal-to-basolateral and basolateral-to-apical transcytosis, but not recycling, suggesting the use of d

110 ponent of the RE, Rab11a, is dispensable for transcytosis, but regulates recycling to the basolateral

111 Inhibiting transcytosis by dynamin blockade increased paracellular

112 The combined data indicated that the transcytosis by GLUT1 and GLUT3 was a pathway of MAN-LIP

113 athway facilitates reabsorption and mediates transcytosis by its pH-dependent binding affinity in end

114 he BBB/BBTB via glucose-transporter-mediated transcytosis by MA.

115 gly induced, whereas pIgR expression and IgA-transcytosis capacity were decreased in cultures from su

116 he extent to which receptor-mediated reverse transcytosis clears mAb from the brain is unknown.

117 The timing of this suppression of transcytosis coincides with the establishment of BBB fun

118 Here, we show that M cell transcytosis depends on the Mtb Type VII secretion machi

119 heir differences in adherence, invasion, and transcytosis efficiencies.

120 us applied to the apical surface, indicating transcytosis efficiency was constant (r(2) = 0.9846; p <

121 Since transcytosis encompasses both sets of events, the full p

122 can occur between (paracellular) or through (transcytosis) endothelial cells, yet little is known abo

123 a reversal of IgG transport with predominant transcytosis from an apical-to-basolateral direction, wh

124 recognizes the Fc domain of IgG and mediates transcytosis from maternal to fetal circulation.

125 apical BBM complexes with megalin during its transcytosis from the BLM.

126 le-dependent redirection of beta(1) integrin transcytosis from the leading edge of migrating cells th

127 cursors was not CD137-dependent, full M cell transcytosis function required expression of CD137 by ra

128 Therefore, the temporal regulation of transcytosis governs the development of a functional BRB

129 Receptor mediated transcytosis harnessing the cellular uptake and transpor

130 n unusually low rate of vesicular transport (transcytosis) has been identified as one of the two uniq

131 tant mice with elevated or reduced levels of transcytosis have delayed or precocious sealing of the B

132 s to be a prerequisite for FcRn-mediated IgG transcytosis; IgG transcytosis was demonstrated in vivo

133 : (i) the toxin itself undergoes binding and transcytosis; (ii) an auxiliary protein, HA35, transport

134 (LDL) in endothelial cells that mediates its transcytosis in a nondegradative manner.

135 oscopy studies further reveal high levels of transcytosis in brain endothelium early in development t

136 ased 3 to 10-fold in Apom(-/-) mice, whereas transcytosis in capillaries and venules remained unchang

137 IgG movement nonspecifically by constitutive transcytosis in caveolae.

138 of BBB function that may act by suppressing transcytosis in CNS endothelial cells.

139 obese mice impaired endothelial cell insulin transcytosis in culture and in vivo.

140 lergens, our study implies CD23-mediated IgE transcytosis in human airway epithelial cells may play a

141 c increase in CNS-endothelial-cell vesicular transcytosis in Mfsd2a(-/-) mice, without obvious tight-

142 ermeability in Apom(-/-) mice, and inhibited transcytosis in penetrating arterioles, but not in pial

143 tor (FcRn), which mediates IgG recycling and transcytosis in peripheral endothelium, was investigated

144 ns are anterogradely trafficked to axons via transcytosis in sympathetic neurons.

145 ffic from apical to basolateral membranes by transcytosis in the absence of toxin binding but only if

146 endocytosis and degradation and fluid-phase transcytosis in the apical-to-basal direction.

147 generated to determine the roles of ColA in transcytosis in vitro and virulence in hamsters.

148 accine-induced antibody capable of enhancing transcytosis in vitro via FcRn may play a role in determ

149 tion of adaptive mucosal immunity is antigen transcytosis, in which luminal antigens are transported

150 Blockade of transcytosis induced a rapid increase in paracellular le

151 ediated viral inhibition (ADCVI) in sera and transcytosis inhibition in rectal secretions.

152 secretions was significantly correlated with transcytosis inhibition.

153 ted, at least in part, by ADCVI activity and transcytosis inhibition.

154 Vb tail, which is dominant negative towards transcytosis, inhibits lumenal accumulation.

155 Both planar transcytosis initiated by Dynamin-mediated endocytosis a

156 ment of a functional BRB, and suppression of transcytosis is a principal contributor for functional b

157 owever, it is not known how this low rate of transcytosis is achieved.

158 Transcytosis is also essential for establishing and main

159 Transferrin receptor 1 (TfR1) mediated transcytosis is an attractive strategy to enhance brain

160 s as infectious particles, the efficiency of transcytosis is extremely poor (less than 0.02% of the i

161 in barrier (BBB) by "molecular Trojan horse" transcytosis is feasible, we synthesized several transpo

162 A functional barrier forms only when transcytosis is gradually suppressed during development.

163 Endosome transport by transcytosis is the primary mechanism by which proteins

164 ral side of endothelial cells facilitated NC transcytosis, likely by helping NC detachment post-trans

165 ons could cross the epithelial barrier via a transcytosis mechanism.

166 d by a relatively nonspecific pinocytosis or transcytosis mechanism.

167 f biophysical characterizations in assessing transcytosis mechanisms.

168 he axonal compartment, suggesting a possible transcytosis model for the dendritic targeting of neurot

169 ng role in the two sub-processes involved in transcytosis: NC binding-uptake depended directly on val

170 specialised features (e.g. receptor-mediated transcytosis) need to be maximally expressed.

171 competition with excess IgG, suggesting IgG transcytosis occurs nonspecifically and originates from

172 n mediates basal recycling and bidirectional transcytosis of albumin and uniquely determines the phys

173 A, but not filamin B, reduced the uptake and transcytosis of albumin by approximately 35 and 60%, res

174 r and pharmacologic approaches, we inhibited transcytosis of albumin in primary human microvascular e

175 ical actin, caused a significant increase in transcytosis of albumin in vitro and in an ex vivo whole

176 , efflux pump activity and receptor-mediated transcytosis of angiopep-2.

177 Our results suggest that pIgR-mediated transcytosis of antagonistic antibodies in dIgA format c

178 The role of CD23 isoforms in transcytosis of antigen and IgE-antigen complexes was as

179 , but not loss of ankyrin binding, prevented transcytosis of apically mis-sorted E-cadherin to the la

180 tricted mobility at the lateral membrane and transcytosis of apically mis-sorted protein to the later

181 We found that transcytosis of both cell-free and cell-associated virus

182 Transcytosis of both IgE and the IC was further verified

183 nd IgG from lysosomal degradation, abolished transcytosis of both types of transgenic albumin and IgG

184 egradation; this process allows apical-basal transcytosis of bound peptides.

185 human endocervical tissue can support direct transcytosis of cell-free virus from the apical to basol

186 This is initiated following transcytosis of cytoplasm from cancer cells into fibrobl

187 Furthermore, interferon-gamma increased the transcytosis of dimeric IgA in cultured tubular cells.

188 rtant part of the immune system by mediating transcytosis of dimeric IgA into mucosal fluids.

189 ny diseases and explored for endocytosis and transcytosis of drug delivery systems.

190 olayer to IL-4 stimulation also enhanced the transcytosis of either human IgE or the IC.

191 These events were associated with decreased transcytosis of Evans blue and increased transendothelia

192 found in the follicle-associated epithelium, transcytosis of fluorescent latex beads was evaluated wi

193 EPCR-mediated endocytosis may facilitate the transcytosis of FVIIa and its clearance from the circula

194 -1 gp41 envelope protein, which mediates the transcytosis of HIV-1 across the mucosal epithelia.

195 ize biological parameters of epithelial cell transcytosis of HIV-1 and assess antiviral Ab blockade o

196 Consistent with the epithelial transcytosis of HIV-IgA immune complexes, the colocaliza

197 GBS entry into host cells and transcytosis of host cells may occur by distinct mechani

198 uman FcRn were used to study the binding and transcytosis of IgE in the form of IgG anti-IgE/IgE ICs.

199 FcRn mediates recycling and transcytosis of IgG and albumin in various cell types.

200 for factors necessary for the bidirectional transcytosis of IgG by the Fcgamma receptor FcRn.

201 se defects were physiologically relevant, as transcytosis of IgG was disrupted, lipid absorption was

202 othelium, was investigated by evaluating the transcytosis of IgGs with native or reduced FcRn engagem

203 e; however, little is known about the actual transcytosis of insulin and how this occurs in the relev

204 Transcytosis of KSI was confirmed in vivo by confocal an

205 ial cell intracellular vesicles in vivo, and transcytosis of LDL across endothelial monolayers requir

206 and polarized Caco-2 cells, the adhesion and transcytosis of M-like cells, the intracellular survival

207 gE in CB sera is the result of FcRn-mediated transcytosis of maternal-derived IgG anti-IgE/IgE ICs.

208 tention through ankyrin-G and apical-lateral transcytosis of mis-localized protein through clathrin.

209 ing to ICAM-1 could drive endocytosis and/or transcytosis of model cargo in different cell types.

210 e kinase HCK regulates apical-to-basolateral transcytosis of non-opsonized and SIgA-opsonized particl

211 ts that Amn/Cubn is required for endocytosis/transcytosis of one or more ligands in the VE during gas

212 onal efflux pumps, and it displays selective transcytosis of peptides and antibodies previously obser

213 eport that this mutation reduces the rate of transcytosis of pIgR and pIgA, and seemingly the rate of

214 Ang II enhances the endocytosis and transcytosis of plasma albumin by podocytes, which may e

215 Whereas papillae are highly dependent on transcytosis of premade material, little is known about

216 TC) stimulated the cellular accumulation and transcytosis of radioactive [(57)Co]Cbl in polarized mon

217 Transcytosis of SIgA-CD71 complexes and intestinal perme

218 t regimen of mucosal antibodies that inhibit transcytosis of SIV across an intact epithelial cell lay

219 Interestingly, no changes in transcytosis of the glycophosphatidylinositol-anchored p

220 the sorting of acid hydrolases to lysosomes, transcytosis of the polymeric immunoglobulin receptor, W

221 Similarly, both ethanol and TSA impaired transcytosis of the single-spanning apical resident amin

222 activate HCK-dependent apical-to-basolateral transcytosis of these particles.

223 h factor (NGF) is necessary for soma-to-axon transcytosis of TrkA receptors in sympathetic neurons, a

224 We investigated FcRn mediated transcytosis of V(H)-matched IgG1 and IgG2 and mutated v

225 rthermore, opsonization enhances M-like-cell transcytosis of V. cholerae strains.

226 llular diffusion, to cell-based dispersal by transcytosis or cytonemes.

227 " receptors internalize Abeta or promote its transcytosis out of the brain, whereas "bad" receptors b

228 fusion of FC5 with Fc increased the rate of transcytosis (Papp) across brain endothelial monolayer b

229 very of CD98hc as a robust receptor-mediated transcytosis pathway for antibody delivery to the brain

230 We have identified a transcytosis pathway used by cholix, an exotoxin secrete

231 stration in mice through a receptor-mediated transcytosis pathway.

232 be transported mainly via the intracellular transcytosis pathway.

233 s while discriminating between recycling and transcytosis pathways polarized in their direction of tr

234 the normal function of apical recycling and transcytosis pathways.

235 mmalian BBB regulator Mfsd2a, which inhibits transcytosis, plays a conserved role in zebrafish, as mf

236 pithelial cells by (i) apical to basolateral transcytosis, potentially contributing to initial EBV pe

237 s VEGF and mPEG crossed the RPE monolayer by transcytosis, predominantly in the apical-to-basal direc

238 R interactions upon acidification during the transcytosis process to allow release of the nanoparticl

239 testinal epithelium (SMI-100) by a vesicular transcytosis process, activate hIL-10 receptors in an en

240 of vascular cell adhesion molecule-1 and the transcytosis protein Caveolin-1 and promoting endothelia

241 The efficiency of HIV-1 transcytosis ranged between 0.05 and 1.21%, depending on

242 sely, the number of endothelial caveolae and transcytosis rate increase as early as 6 hr after stroke

243 and low NC valencies rendered less efficient transcytosis rates than an intermediate valency formulat

244 s associated with an increase in endothelial transcytosis rather than a loss of tight junctions.

245 Leptin crosses the blood-brain barrier by transcytosis rather than undergoing intracellular degrad

246 endothelium of the BBB, but any influence on transcytosis remains unclear.

247 Insulin transcytosis required dynamin but was unaffected by cave

248 This active transcytosis requires normal caveolin-1 expression.

249 membrane mobility or loss of apical-lateral transcytosis result in partial mis-sorting of E-cadherin

250 Receptor mediated transcytosis (RMT) is a common mechanism used by protein

251 d is the use of endogenous receptor-mediated transcytosis (RMT) systems as a means to shuttle a targe

252 ansport systems, including receptor-mediated transcytosis (RMT).

253 ve exocytosis component of the transcellular transcytosis route.

254 Importantly, the transcytosis specific activity (percent inhibition/total

255 ficantly reduced the efficiency of IgE or IC transcytosis, suggesting a specific receptor-mediated tr

256 We show that exploitation of the transcytosis system allows enhanced whole-organ imaging

257 ow that LRP-1 is associated with endothelial transcytosis that does not involve acidification of carg

258 lity that limited passage of cell-free HIV-1 transcytosis through an intact genital epithelium occurs

259 half-life from minutes to days and mediates transcytosis through binding to the neonatal Fc receptor

260 Thus, during its transcytosis through epithelial cells, HIV-specific IgA

261 , DeltacolA mutant displayed much-attenuated transcytosis through HEK293 and HUVEC monolayers, and le

262 interacting protein 2 (Rab11-FIP2) regulates transcytosis through its interactions with Rab11a and my

263 ion in invasion did not significantly affect transcytosis through M-like cells at early time points.

264 V-1 attachment, they enhance viral entry and transcytosis through PGECs.

265 These data suggest that during transcytosis through pIgR-positive cells, exposure to PD

266 Transcytosis through the floor of the subcapsular sinus

267 stinct from those conferring cell-free virus transcytosis through the genital epithelium.

268 t takes place by dynamin-dependent vesicular transcytosis through the lymphatic endothelial cells in

269 e cell to the basolateral plasma membrane by transcytosis, thus breeching the intestinal barrier.

270 ECM-abutting cell surface and initiating its transcytosis to an apical membrane initiation site for l

271 ALK-1 internalization strongly re-duces LDL transcytosis to levels seen with ALK-1 deficiency.

272 specialized tight junctions and low rates of transcytosis to limit the flux of substances between blo

273 that endothelial DARC facilitates chemokine transcytosis to promote neutrophil recruitment.

274 transient pool of the protein that undergoes transcytosis to the apical membrane.

275 After transcytosis to the apical surface, the extracellular, l

276 s reveal the extent of physiological protein transcytosis to the healthy brain, a mechanism of widesp

277 normal leaky vasculature for tumor access, a transcytosis transport pathway that is regulated by neur

278 axons via an endocytosis-dependent pathway (transcytosis), traversing somatodendritic endosomes.

279 sported across the BBB via receptor-mediated transcytosis using the brain-penetrant peptide Angiopep-

280 Transcytosis via caveolae is critical for maintaining va

281 ure, CRP suppressed endothelial cell insulin transcytosis via FcgammaRIIB activation and eNOS antagon

282 InlA aids L. monocytogenes transcytosis via interaction with the E-cadherin recepto

283 trans-Golgi network and the other half from transcytosis via the basolateral membrane in MDCK cells.

284 e we use electron tomography to make jejunal transcytosis visible directly in space and time, develop

285 ains the opposite behavior of NC valency for transcytosis vs. lysosomal transport.

286 d epithelial cells showed that FcRn-mediated transcytosis was blocked by the Fc fragment of IgG, but

287 Transcytosis was carried out by exposing sera and SIVmac

288 site for FcRn-mediated IgG transcytosis; IgG transcytosis was demonstrated in vivo by translocation o

289 Caveolar protein transcytosis was found to have a prevailing role in over

290 This redirection in beta(1) integrin transcytosis was inhibited by depolymerization of microt

291 Significantly higher viral transcytosis was observed in the presence of MPA.

292 Instead, insulin transcytosis was significantly inhibited by the clathrin

293 Apical to basolateral EBV transcytosis was substantially reduced by amiloride, an

294 In contrast, basolateral to apical EBV transcytosis was substantially reduced by nystatin, an i

295 between NC targeting valency and the rate of transcytosis, where high and low NC valencies rendered l

296 undergoes caveolae-mediated endocytosis and transcytosis, which enables transendothelial and transce

297 ic infection, and (ii) basolateral to apical transcytosis, which may enable EBV secretion into saliva

298 Finally, we documented extensive albumin transcytosis with vesicular and tubular delivery to and

299 In summary, we provide evidence of a transcytosis within the kidney tubular system that prote

300 Rab25 regulate a sorting step that specifies transcytosis without affecting recycling.