ライフサイエンスコーパス: transcytotic

1 Thus, FcRn transcytotic and recycling sorting steps are distinct.

2 osis in hepatocytes, causing accumulation of transcytotic carriers for the polymeric IgA receptor (pI

3 icle carrier fraction (CVCF), which includes transcytotic carriers.

4 vesicle carrier fraction (CVCF) enriched in transcytotic carriers; (2) slow delivery of [35S]-labele

5 h multiple routes, including via specialized transcytotic cells called microfold cells (M cell).

6 Transcytotic commensal penetration may contribute to ini

7 y immunoisolation and found that no uniquely transcytotic elements were present, because recycling re

8 endosomal markers but was distinct from the transcytotic intermediate, the subapical compartment.

9 In serum, it is a transcytotic iron transporter across the blood-brain bar

10 the polymeric IgA receptor (pIgAR)) but also transcytotic markers (dIgA and the 120-kDa form of pIgAR

11 Both were enriched in transcytotic markers and depleted in ER and Golgi marker

12 rab11a-containing endosomes and, unlike the transcytotic markers, did not distribute to the plasma m

13 nes that contain apical ABC transporters and transcytotic markers, permitting their targeting to the

14 bendothelial matrix of vascular tissues by a transcytotic mechanism and serves as a catalyst of ECM p

15 li, apical ABC transporters colocalized with transcytotic membrane proteins in rab11a-containing endo

16 K cells promotes a switch from a direct to a transcytotic mode of apical protein delivery and other t

17 Our results suggest that in WIF-B cells, transcytotic molecules pass through a subapical compartm

18 To characterize the transcytotic passage of albumin through lens epithelial

19 Transcytotic passage of albumin was monitored for 4 hour

20 find that sorting of cholera toxin into this transcytotic pathway bypasses retrograde transport to th

21 Here, we report a novel transcytotic pathway employed by AP-1B-deficient epithel

22 erefore warranting consideration of the FcRn transcytotic pathway for further investigation as a mean

23 They define a transcytotic pathway important for the physiology of nat

24 vert an infectious outcome, we modulated the transcytotic pathway in polarized Madin-Darby canine kid

25 The transcytotic pathway of vitamin B12 has previously been

26 is intermediate in the basolateral-to-apical transcytotic pathway remained functional.

27 suggest the existence of a dendrite-to-axon transcytotic pathway to achieve axonal accumulation.

28 l protein endolyn-78 partially resembled the transcytotic pathway, since anti-endolyn-78 antibodies w

29 n indicate that rab3D is associated with the transcytotic pathway.

30 viral particles may cross the BBB using the transcytotic pathway.

31 The paracellular and transcytotic pathways of biliary excretion, assessed by

32 The basolateral recycling and transcytotic pathways of epithelial cells were previousl

33 , these data indicate that the secretory and transcytotic pathways remain polarized in cholestatic he

34 on the apical and basolateral recycling and transcytotic pathways, demonstrating that these pathways

35 ptor segregation into distinct recycling and transcytotic pathways.

36 ctively regulate the apical recycling and/or transcytotic pathways.

37 that the density of recycling receptors and transcytotic pIgR in RRC membranes was similar to that i

38 y enriched in recycling receptors and in the transcytotic polymeric Ig receptor (pIgR).

39 on of Wingless that is required for both the transcytotic process and signal transduction in dorsal c

40 caveolae and clathrin-coated vesicles in the transcytotic process.

41 However, a transcytotic protein did reach the apical surface after

42 specifically inhibits the caveolae-mediated transcytotic route readily used in the periphery.

43 c tail motif (YRSL) are unable to access the transcytotic route.

44 We have evaluated transcytotic routes in MDCK cells for their ability to g

45 IgG transport, we examined LIS and endocytic/transcytotic structures from neonatal and weaned animals

46 This findings confirm the transcytotic targeting of cCAM105 reported in earlier st

47 poles of polarized epithelial cells and that transcytotic traffic is likely to require Rab11a-depende

48 Synaptic and transcytotic trafficking thus are restricted to particul

49 red BRE cells by an NOS-dependent process of transcytotic transport in caveolae.

50 that rab17 and syntaxin 2 mediate fusion of transcytotic vesicles at the apical surface.

51 cytoplasmic domain of pIgAR to immunoisolate transcytotic vesicles from a fraction (CV1, rho = 1.146)

52 raction on anti-Rab1a was similar to that of transcytotic vesicles immunoisolated from the same fract

53 R), suggesting that Rab1a is associated with transcytotic vesicles in rat liver.

54 Fusion of recycling and transcytotic vesicles with the apical and basolateral pl

55 a p22 peptide block the targeting/fusion of transcytotic vesicles with the apical plasma membrane, b

56 However, the association of the transcytotic vesicles with the microtubules was not sens

57 ated with both ER to Golgi and postendosomal transcytotic vesicles, and 2) multiple GTP-binding prote

58 On endosomes and transcytotic vesicles, FGD6 regulates retromer-dependent

59 b1a appeared to be enriched in postendosomal transcytotic vesicles, whereas those isolated on pIgAR c

60 associated proteins and increased numbers of transcytotic vesicles, which occasionally contained mHtt

61 inuous microvascular endothelium function as transcytotic vesicular carriers for protein molecules >

62 scles) in which they have been identified as transcytotic vesicular carriers.

63 and dibutyryl cAMP (DBcAMP), stimulators of transcytotic vesicular transport, increased the biliary