ライフサイエンスコーパス: transfer RNA

1 te and releasing the peptide from the P-site transfer RNA.

2 separated 30S and 50S subunits and initiator transfer RNA.

3 ate, resulting in a P/E hybrid state for the transfer RNA.

4 ce complementary to the 3' end of a cellular transfer RNA.

5 t attachment of amino acids to their cognate transfer RNA.

6 solely responsible for the aminoacylation of transfer RNA.

7 of the nascent protein chain from the P-site transfer RNA.

8 ables the deletion of a previously essential transfer RNA.

9 alytic, ribosomal, small nuclear, micro, and transfer RNAs.

10 both and occupies the space normally used by transfer RNAs.

11 maturation of both nuclear and mitochondrial transfer RNAs.

12 function, plus three ribosomal RNAs, and 17 transfer RNAs.

13 dogenous 5'-phosphate-capped RNAs, including transfer RNAs.

14 DNA replication, chromosomal breakpoints and transfer RNAs.

15 ression of amino acid biosynthesis genes and transfer RNAs.

16 ze the specific pairings of amino acids with transfer RNAs.

17 erved proteins, three ribosomal RNAs, and 15 transfer RNAs.

18 eading the aminoacylation status of specific transfer RNAs.

19 epressible 2 (GCN2) kinase through uncharged transfer RNAs.

20 n synII, mainly caused by the deletion of 13 transfer RNAs.

21 g for 81 protein, four ribosomal RNAs and 29 transfer RNAs.

22 evidence for the canonical functions of the transferred RNA.

23 tate of translocation, in which the peptidyl-transfer RNA 3'-CCA end is improperly docked in the pept

24 perform simulations of large-scale aminoacyl-transfer RNA (aa-tRNA) rearrangements during accommodati

25 ribosomes exhibit perturbations in aminoacyl-transfer RNA (aa-tRNA) selection and altered pre-translo

26 r Tu (EF-Tu) binds to all standard aminoacyl transfer RNAs (aa-tRNAs) and transports them to the ribo

27 based assay to identify anticodon engineered transfer RNAs (ACE-tRNA) which can effectively suppress

28 We evolved a transfer RNA adenosine deaminase to operate on DNA when

29 nd other proteins in response to fluctuating transfer RNA aminoacylation levels under various nutriti

30 Puromycin is an amino-acyl transfer RNA analog widely employed in studies of protei

31 mportance of the 2'-hydroxyl of the peptidyl-transfer RNA and a Bronsted coefficient near zero have b

32 as the complex responsible for production of transfer RNA and a limited number of other small RNAs.

33 on of Met metabolism in mat3 pollen affected transfer RNA and histone methylation levels.

34 omprising a 40S ribosomal subunit, initiator transfer RNA and initiation factors (eIF) 2, 3, 1 and 1A

35 Ribosomal ribonucleic acid (RNA), transfer RNA and other biological or synthetic RNA polym

36 nt oxygenases that catalyse hydroxylation of transfer RNA and ribosomal proteins have been shown to b

37 in non-coding RNAs, enhances the function of transfer RNA and ribosomal RNA by stabilizing the RNA st

38 RNA modifications were mostly identified on transfer RNA and ribosomal RNA until the last decade, wh

39 Ribosomes catalyze protein synthesis using transfer RNAs and auxiliary proteins.

40 y the ribosome requires the translocation of transfer RNAs and messenger RNA by one codon after each

41 or binding protein CTCF, housekeeping genes, transfer RNAs and short interspersed element (SINE) retr

42 that our two species had extremely truncated transfer RNAs and that gene overlaps occurred much more

43 We further find that SLFN11 binds transfer RNA, and counteracts changes in the tRNA pool e

44 HPF and YfiA overlap with those of the mRNA, transfer RNA, and initiation factors, which prevents tra

45 ation resulting from limiting ribosomal RNA, transfer RNA, and ribosomal protein mRNA.

46 process of bringing together mRNA, initiator transfer RNA, and the ribosome, is therefore of critical

47 sekeeping functions in cells-ribosomal RNAs, transfer RNAs, and small nucleolar RNAs.

48 Transfer RNAs are ancient molecules, perhaps even predat

49 ssential for the maturation of ribosomal and transfer RNA as well as the rapid degradation of messeng

50 0S ribosome complexed with EF-G, RRF and two transfer RNAs at a resolution of 3.5 angstrom.

51 We speculate that pools of transfer RNA available for protein translation impact on

52 locations of eIF1, eIF1A, mRNA and initiator transfer RNA bound to the small ribosomal subunit and pr

53 Eukaryotic transfer RNAs can become selectively fragmented upon var

54 proteins, Pnkp and Hen1, was able to repair transfer RNAs cleaved by ribotoxins in vitro.

55 ysine, encoded by poly(A), favors a peptidyl-transfer RNA conformation suboptimal for peptide bond fo

56 Aminoacyl-transfer RNAs contain four standardized units: amino aci

57 ome function (e.g., increased affinities for transfer RNAs, decreased rates of peptidyl-transfer), an

58 ation of the HIS2 transcription start due to transfer RNA deletion and loxPsym site insertion.

59 diet (HFD), we showed that a subset of sperm transfer RNA-derived small RNAs (tsRNAs), mainly from 5'

60 Transfer-RNA-derived small RNAs (tsRNAs; also called tRN

61 cent work indicates that many cells can also transfer RNA directly via cell-cell trafficking of nanom

62 ctedly, we found that codons decoded by rare transfer RNAs do not lead to slow translation under nutr

63 2-guanosine triphosphate-initiator methionyl transfer RNA (eIF2.GTP.Met-tRNA(i )(Met)).

64 of the 50S ribosomal subunit to an initiator transfer RNA (fMet-tRNA(fMet))-containing 30S ribosomal

65 We present evidence that the entire set of transfer RNAs for all twenty amino acids are encoded in

66 Transfer RNA fragments (tRFs) are an established class o

67 microRNA levels and concomitant increases of transfer RNA fragments (tRFs) targeting cholinergic tran

68 iculum (ER) stress through the production of transfer RNA fragments that interfere with translation i

69 uch as snoRNAs (small nucleolar RNAs), tRNA (transfer RNA) fragments, and Y-RNAs in cellular processe

70 We developed Slide-seq, a method for transferring RNA from tissue sections onto a surface cov

71 osed EVs of 30-150 nm in diameter, which can transfer RNA, functional proteins, lipids, and metabolit

72 A transfer RNA fusion engineered into domain II of the int

73 he pathogenic A3243T mutation in the leucine transfer RNA gene (tRNAleu)].

74 n RNA sequence in the chloroplast isoleucine transfer RNA gene (trnI.2) located in the rRNA operon.

75 ding genes (PCGs), 2 ribosomal RNA genes, 22 transfer RNA genes and an 834 bp intergenic region assum

76 y centromeres and include interactions among transfer RNA genes, among origins of early DNA replicati

77 protein coding genes, 2 ribosomal RNA and 22 transfer RNA genes, and a control region varying in size

78 rotein-coding genes, 2 ribosomal RNAs and 22 transfer RNA genes.

79 nits), with each t-unit containing three pre-transfer RNA genes.

80 -derived small RNAs (tsRNAs), mainly from 5' transfer RNA halves and ranging in size from 30 to 34 nu

81 me exit tunnel, after their covalent bond to transfer-RNA has been broken, has not been experimentall

82 Human mitochondrial methionine transfer RNA (hmtRNA(Met)(CAU)) has a unique post-transc

83 igated metabolites such as aminoacyl-charged transfer RNA in the T-box system, or protein-bound metab

84 link specific amino acids with their cognate transfer RNAs in a critical early step of protein transl

85 stop codon by utilizing switchable designer transfer RNAs in Escherichia coli .

86 when the ribosome lacked accommodated A-site transfer RNA, indicative of low codon optimality.

87 iral subgenomic (SG), cellular messenger and transfer RNAs into released virions.

88 Transfer RNA is a highly regulated functional RNA that u

89 Transfer RNA is heavily modified and plays a central rol

90 Transfer RNA is one of the most richly modified biologic

91 Selenocysteinyl transfer RNA knockout mice (Trsp(fl/fl)LysM(Cre)) were u

92 During protein synthesis, deacylated transfer RNAs leave the ribosome via an exit (E) site af

93 ed that cells use an elongator leucine-bound transfer RNA (Leu-tRNA) to initiate translation at crypt

94 After excision of the intron, transfer RNA ligase joins the severed exons, lifting the

95 t stabilize DNA substrates in a constrained, transfer RNA-like conformation.

96 some of these mobile transcripts contained a transfer RNA-like structure.

97 e factors promote hydrolysis of the peptidyl-transfer RNA linkage in response to recognition of a sto

98 During ribosomal and transfer RNA maturation, external transcribed spacer (ET

99 all subunits of the ribosome, with initiator transfer RNA (Met-tRNA(i)(Met)) positioned over the star

100 First, methionylated initiator methionine transfer RNA (Met-tRNAi(Met)), eukaryotic initiation fac

101 rity to the anticodon of methionyl initiator transfer RNA (Met-tRNAi).

102 nticodon loop in the mitochondrially encoded transfer RNA methionine (mt-tRNA(Met)).

103 ons within the reaction centre of a peptidyl-transfer RNA mimic.

104 nsible for deoxyribonucleoside synthesis and transfer RNA modification appear to be crucial, as no al

105 M), its biosynthetic pathway and its role in transfer RNA modification.

106 Transfer RNA modifications play pivotal roles in protein

107 Here, using the transfer RNA molecule as a structural building block, we

108 ription, retroviruses require annealing of a transfer RNA molecule to the U5 primer binding site (U5-

109 Translocation of messenger and transfer RNA (mRNA and tRNA) through the ribosome is a c

110 ate the various steps of translation such as transfer RNA-mRNA movement.

111 nt they are involved in the translocation of transfer RNA (mt-tRNA) is unclear.

112 philus 70S ribosome along with the initiator transfer RNA N-formyl-methionyl-tRNA(i) (fMet-tRNA(i)(fM

113 ylguanosine and N(2)(2)-dimethylguanosine in transfer RNA occur at five positions in the D and antico

114 s, three putative open reading frames and 33 transfer RNAs of 19 amino acids for peptide synthesis.

115 d light on the movement of messenger RNA and transfer RNA on the ribosome after each peptide bond is

116 d be required to ensure functional impact of transferred RNA on brain recipient cells and predict the

117 During translation, the primary substrates, transfer RNAs, pass through binding sites formed between

118 C5 is the protein subunit of the transfer RNA processing ribonucleoprotein enzyme RNase P

119 relate with an increased content of glutamyl-transfer RNA reductase.

120 old ntrc seedlings, the contents of glutamyl-transfer RNA reductase1 (GluTR1) and CHLM are reduced.

121 Transfer RNAs represent the largest, most ubiquitous cla

122 d in human circulation, including microRNAs, transfer RNAs, ribosomal RNA, and yRNA fragments.

123 d degradation mechanisms for messenger RNAs, transfer RNAs, ribosomal RNAs, and noncoding RNAs.

124 g loops, and show that tiles inserted into a transfer RNA scaffold can be overexpressed in bacterial

125 ific deletion of Trsp, a gene that encodes a transfer RNA (Sec tRNA) required for the insertion of se

126 ploits two rRNA nucleotides also used during transfer RNA selection to drive messenger RNA compaction

127 the cytochrome P450 superfamily of enzymes, transfer RNA selenocysteine synthase, formiminotransfera

128 t are highly expressed and up to 35 putative transfer RNAs, some of which contain enigmatic introns.

129 However, even the classic transfer RNA structure contains features that are overlo

130 Due to differential transfer RNA supply within the cell, synonymous codons a

131 nregulating TOR signalling via LARS-1/leucyl-transfer RNA synthase.

132 ture and function of Escherichia coli prolyl-transfer RNA synthetase (Ec ProRS), a member of the amin

133 animal models support a key role of histidyl-transfer RNA synthetase (HisRS; also known as Jo-1) in t

134 nse pathway, through inhibiting human prolyl-transfer RNA synthetase (ProRS) to cause intracellular a

135 hetase (Ec ProRS), a member of the aminoacyl-transfer RNA synthetase family, has been investigated us

136 was used to design a pocket within threonyl-transfer RNA synthetase from the thermophile Pyrococcus

137 was protective in adults with anti-threonyl-transfer RNA synthetase or anti-U RNP autoantibodies (OR

138 l-prolyl-transfer RNA synthetase, glutaminyl-transfer RNA synthetase, elongation factor 2, elongation

139 or in protein biosynthesis (glutamyl-prolyl-transfer RNA synthetase, glutaminyl-transfer RNA synthet

140 e discovery of multiple orthogonal aminoacyl-transfer RNA synthetase/tRNA pairs.

141 zyloxycarbonyl amino acid using a pyrrolysyl transfer RNA synthetase/tRNACUA pair in mammalian cells

142 The Methanococcus jannaschii tyrosyl-transfer-RNA synthetase-tRNA(CUA) (MjTyrRS-tRNA(CUA)) an

143 conserved in evolution, bacterial aminoacyl-transfer RNA synthetases are unable to acylate eukaryoti

144 s (mistranslation) is prevented by aminoacyl transfer RNA synthetases through their accurate aminoacy

145 d translation machinery, including aminoacyl transfer RNA synthetases with specificities for all 20 a

146 te-specific domains from bacterial aminoacyl-transfer RNA synthetases.

147 oribouridine, a modified nucleoside found in transfer RNA that enables both faster and more-accurate

148 se-pairs with eIF2-bound initiator methionyl transfer RNA to form a 48S initiation complex.

149 t uses amber and evolved quadruplet-decoding transfer RNAs to encode numerous pairs of distinct unnat

150 would preclude the binding of messenger and transfer RNAs to the ribosome, suggesting that PSRP1 is

151 e aminoacyl-tRNA synthetases covalently link transfer RNAs to their cognate amino acids.

152 ion machinery are covered in turn, including transfer RNAs, translation factors, and the ribosome.

153 ction mechanism, similar to that employed in transfer RNA translocation on the ribosome by EF-G, tran

154 , deletion of subtelomeric regions, introns, transfer RNAs, transposons, and silent mating loci as we

155 ecific RNA-RNA complex formed between a host transfer RNA (tRNA(Lys)(3)) and a region at the 5' end o

156 hia coli strain that harbors a Sep-accepting transfer RNA (tRNA(Sep)), its cognate Sep-tRNA synthetas

157 ncluding recruitment of mitochondrial valine transfer RNA (tRNA(Val)) to play an integral structural

158 ) was discovered in the wobble position of a transfer RNA (tRNA) 47 years ago, yet the final biosynth

159 Nase P), the ribonucleoprotein essential for transfer RNA (tRNA) 5' maturation, is challenged in the

160 Genetic perturbations causing uncharged transfer RNA (tRNA) accumulation activated ISR reporter

161 tion rate as parameters related to codon and transfer RNA (tRNA) adaptation.

162 Accurate transfer RNA (tRNA) aminoacylation by aminoacyl-tRNA syn

163 of genes responsible for amino acid supply, transfer RNA (tRNA) aminoacylation, and protein folding.

164 protein and cell function, requires accurate transfer RNA (tRNA) aminoacylation.

165 a bifunctional molecule that acts as both a transfer RNA (tRNA) and a messenger RNA (mRNA), and SmpB

166 modification that occurs most extensively in transfer RNA (tRNA) and ribosomal RNA (rRNA).

167 clease activity in vitro, but cleaves within transfer RNA (tRNA) anti-codon loops when purified CysK

168 Posttranscriptional modifications in transfer RNA (tRNA) are often critical for normal develo

169 report that both mitochondrial and cytosolic transfer RNA (tRNA) bind to cytochrome c.

170 ylation of its target site within the E-site transfer RNA (tRNA) binding region of the 28S ribosomal

171 t affects both amino acid discrimination and transfer RNA (tRNA) binding.

172 n using the in vitro processing of precursor transfer RNA (tRNA) by ribonuclease P as a model system.

173 ss, requiring accurate amino acid selection, transfer RNA (tRNA) charging and mRNA decoding on the ri

174 t shock, or ultraviolet irradiation promotes transfer RNA (tRNA) cleavage and accumulation of tRNA-de

175 sing a messenger RNA (mRNA) and an uncharged transfer RNA (tRNA) cognate to the terminal mRNA codon b

176 Transfer RNA (tRNA) decodes mRNA codons when aminoacylat

177 studies, we show that FthB is a trans-acting transfer RNA (tRNA) editing protein, which hydrolyzes fl

178 The ribosome selects a correct transfer RNA (tRNA) for each amino acid added to the pol

179 ously reported technology termed Fluorescent transfer RNA (tRNA) for Translation Monitoring (FtTM), f

180 er, a recently reported tool for identifying transfer RNA (tRNA) fragments in deep sequencing data, e

181 analyzed the immunostimulatory potential of transfer RNA (tRNA) from different bacteria.

182 Transfer RNA (tRNA) genes (tDNAs), which are transcribed

183 Transfer RNA (tRNA) genes and other RNA polymerase III t

184 Transfer RNA (tRNA) genes are among the most highly tran

185 The human genome encodes hundreds of transfer RNA (tRNA) genes but their individual contribut

186 ts localizing within a single nucleolus, and transfer RNA (tRNA) genes present in an adjacent cluster

187 4L), two ribosomal RNA (srRNA and lrRNA), 22 transfer RNA (tRNA) genes, and two copies of D-loop cont

188 bp) and contains 13 protein-coding genes, 22 transfer RNA (tRNA) genes, two ribosomal RNA (rRNA) gene

189 ur frequently at RNA-polymerase-III-occupied transfer RNA (tRNA) genes, which have been implicated in

190 direct entry is central to the processing of transfer RNA (tRNA) in E. coli, one of the core function

191 locking accommodation of the first aminoacyl transfer RNA (tRNA) into the A site.

192 Histidine transfer RNA (tRNA) is unique among tRNA species as it c

193 Transfer RNA (tRNA) links messenger RNA nucleotide seque

194 Transfer RNA (tRNA) methylation is necessary for the pro

195 olarity and morphology, vacuole trafficking, transfer RNA (tRNA) modification and other functions.

196 h the predicted fraction of correctly folded transfer RNA (tRNA) molecules, thereby revealing a bioph

197 attachment of amino acids to their matching transfer RNA (tRNA) molecules.

198 e simultaneously binds up to three different transfer RNA (tRNA) molecules.

199 ons that are suggested to be associated with transfer RNA (tRNA) movement through the ribosome (trans

200 ecific ribosomal ribonucleic acid (rRNA) and transfer RNA (tRNA) nucleotides.

201 thesis: production of non-cognate amino acid:transfer RNA (tRNA) pairs by aminoacyl-tRNA synthetases

202 idyltransferases] add CCA onto the 3' end of transfer RNA (tRNA) precursors without using a nucleic a

203 Here we combined ribosome and transfer RNA (tRNA) profiling to investigate the relatio

204 nal modification of messenger RNA (mRNA) and transfer RNA (tRNA) provides an additional layer of regu

205 he biophysical and biochemical properties of transfer RNA (tRNA) so that it is optimized for particip

206 ons have attempted to distinguish individual transfer RNA (tRNA) species based on the associated pore

207 ing the ubiquitously expressed enzyme glycyl-transfer RNA (tRNA) synthetase (GlyRS).

208 tion mutant of rrt-1 that encodes an arginyl-transfer RNA (tRNA) synthetase, an enzyme essential for

209 To better enable such efforts, flexizymes (transfer RNA (tRNA) synthetase-like ribozymes that recog

210 evelopment and application of the pyrrolysyl-transfer RNA (tRNA) synthetase/tRNA pair for unnatural a

211 Aminoacyl-transfer RNA (tRNA) synthetases (RS) are essential compo

212 progressively added to cytoplasmic aminoacyl transfer RNA (tRNA) synthetases during evolution.

213 Protein biosynthesis requires aminoacyl-transfer RNA (tRNA) synthetases to provide aminoacyl-tRN

214 pathologies are caused by editing defects of transfer RNA (tRNA) synthetases, which preserve genetic

215 ternal loop that interacts with the peptidyl-transfer RNA (tRNA) T-loop.

216 Here we report a novel transfer RNA (tRNA) tandem repeat on human chromosome 1q

217 Coupled translocation of messenger RNA and transfer RNA (tRNA) through the ribosome, a process cata

218 Pase elongation factor Tu (EF-Tu) delivers a transfer RNA (tRNA) to the ribosome.

219 Transfer RNA (tRNA) translocates inside the ribosome dur

220 ves the movement of messenger RNA (mRNA) and transfer RNA (tRNA) with respect to the ribosome.

221 n and read-through of these stop codons by a transfer RNA (tRNA), although it requires the formation

222 ate of subunit joining is coupled to the IF, transfer RNA (tRNA), and mRNA codon compositions of the

223 t of m(1) A, m(1) G, m(3) C modifications in transfer RNA (tRNA), but they work poorly on m(2)2 G.

224 MTRES1) eject the nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosome

225 cysteine, the 21st amino acid, occurs on its transfer RNA (tRNA), tRNA(Sec).

226 g RNAs, such as pre-ribosomal RNA (rRNA) and transfer RNA (tRNA), which are produced by RNA polymeras

227 Here, we show that rhizobial transfer RNA (tRNA)-derived small RNA fragments (tRFs) a

228 -2 (VPI-2) is a 57-kb region integrated at a transfer RNA (tRNA)-serine locus that encompasses VC1758

229 r the exit channel and Rqc2p over the P-site transfer RNA (tRNA).

230 defining the 3D architecture and dynamics of transfer RNA (tRNA).

231 ized role of TET-mediated m(5)C oxidation in transfer RNA (tRNA).

232 ans whose biosynthesis occurs on its cognate transfer RNA (tRNA).

233 n the ribosome, labeled at the L1 stalk, and transfer RNA (tRNA).

234 ibosomal subunit to messenger RNA (mRNA) and transfer RNA (tRNA).

235 rect attachment of a cognate amino acid to a transfer RNA (tRNA).

236 includes a specific, nuclear genome-encoded, transfer RNA (tRNA[Ser]Sec).

237 Transfer RNAs (tRNA) are quintessential in deciphering t

238 iogenin-mediated endonucleolytic cleavage of transfer RNAs (tRNA) leading to an accumulation of 5' tR

239 d translocation of messenger RNAs (mRNA) and transfer RNAs (tRNA) through the ribosome takes place fo

240 t the ribosome active sites interacting with transfer RNAs (tRNA), we further discover that self-rene

241 Because human tyrosyl transfer-RNA (tRNA) synthetase (TyrRS) translocates to t

242 small Cajal body-specific RNA [scaRNA], and transfer RNA [tRNA] fragments) across 11 mouse tissues b

243 The sulfur-containing nucleosides in transfer RNA (tRNAs) are present in all three domains of

244 hich include small nucleolar RNAs (snoRNAs), transfer RNAs (tRNAs) and introns, whereas endo-siRNAs c

245 on (PRE) complex and facilitates movement of transfer RNAs (tRNAs) and messenger RNA (mRNA) by one co

246 plays a crucial role in the translocation of transfer RNAs (tRNAs) and messenger RNA (mRNA) during tr

247 scripts are dominated by full-length, mature transfer RNAs (tRNAs) and other small noncoding RNAs (nc

248 Transfer RNAs (tRNAs) are a major class of noncoding RNA

249 The fragments that derive from transfer RNAs (tRNAs) are an emerging category of regula

250 Transfer RNAs (tRNAs) are central players in protein syn

251 Transfer RNAs (tRNAs) are central to protein synthesis a

252 Posttranscriptional modifications of transfer RNAs (tRNAs) are critical for all core aspects

253 Transfer RNAs (tRNAs) are essential for protein synthesi

254 Eukaryotic transfer RNAs (tRNAs) are exported from the nucleus, the

255 Transfer RNAs (tRNAs) are primarily viewed as static con

256 Transfer RNAs (tRNAs) are the macromolecules that transf

257 In eukaryotes, transfer RNAs (tRNAs) are transcribed in the nucleus yet

258 Transfer RNAs (tRNAs) are ubiquitous across the tree of

259 the most abundant and conserved RNA species, transfer RNAs (tRNAs) are well known for their role in r

260 n the anticodon of Escherichia coli tyrosine transfer RNAs (tRNAs) at position 35.

261 Posttranscriptional modifications of transfer RNAs (tRNAs) at the wobble uridine 34 (U34) bas

262 lves endonucleolytic cleavage of cytoplasmic transfer RNAs (tRNAs) by ribonucleases that are normally

263 gulate the synthesis of 5S ribosomal RNA and transfer RNAs (tRNAs) by RNA polymerase (Pol) III, as we

264 Bacterial transfer RNAs (tRNAs) contain evolutionarily conserved s

265 In all organisms, transfer RNAs (tRNAs) contain numerous modified nucleoti

266 Heretofore, no evidence suggested that transfer RNAs (tRNAs) could also be exploited.

267 ated reductions in the abundance of numerous transfer RNAs (tRNAs) dominated the microarray data and

268 The anticodon stem-loop (ASL) of transfer RNAs (tRNAs) drives decoding by interacting dir

269 Transfer RNAs (tRNAs) function in translational machiner

270 The evolution of alloacceptor transfer RNAs (tRNAs) has been traditionally thought to

271 All canonical transfer RNAs (tRNAs) have a uridine at position 8, invo

272 rimarily responsible for the 5 maturation of transfer RNAs (tRNAs) in all domains of life.

273 Isolated, fully modified native bacterial transfer RNAs (tRNAs) induced significant secretion of I

274 sine/cytosine/adenine (CCA) to the 3' end of transfer RNAs (tRNAs) is essential for translation and i

275 Transfer RNAs (tRNAs) perform essential tasks for all li

276 Besides translation, transfer RNAs (tRNAs) play many non-canonical roles in v

277 Transfer RNAs (tRNAs) represent the single largest, best

278 Transfer RNAs (tRNAs) require the absolutely conserved s

279 leic acids (sRNAs), primarily the 5' ends of transfer RNAs (tRNAs) termed tRNA fragments (trfRNAs).

280 It has been known that mature transfer RNAs (tRNAs) that are encoded in the nuclear ge

281 sms to acylate (or charge) these monomers to transfer RNAs (tRNAs) to make aminoacyl-tRNA substrates

282 factor Tu (EF-Tu), which delivers aminoacyl-transfer RNAs (tRNAs) to the ribosome.

283 ed into nascent proteins by misaminoacylated transfer RNAs (tRNAs) used in a coupled transcription/tr

284 In higher eukaryotes, transfer RNAs (tRNAs) with the same anticodon are encode

285 protein biosynthesis, namely the charging of transfer RNAs (tRNAs) with their cognate amino acids.

286 tidyltransferase] adds CCA to the 3' ends of transfer RNAs (tRNAs), a critical step in tRNA biogenesi

287 oncoding RNAs such as small RNAs (sRNAs) and transfer RNAs (tRNAs), establishing a previously unappre

288 s (ncRNAs) including ribosomal RNAs (rRNAs), transfer RNAs (tRNAs), small nuclear RNAs (snRNAs), and

289 d previously undescribed CRISPR-Cas systems, transfer RNAs (tRNAs), tRNA synthetases, tRNA-modificati

290 ced at the wobble uridines at position 34 in transfer RNAs (tRNAs), which serve to optimize codon tra

291 each codon is monitored by stable binding of transfer RNAs (tRNAs)-labelled with distinct fluorophore

292 enosine 37 (A37) in several Escherichia coli transfer RNAs (tRNAs).

293 increased amounts of 5' fragments of glycine transfer RNAs (tRNAs).

294 cherichia coli histone-like protein H-NS and transfer RNAs (tRNAs).

295 aryotes involves endonucleolytic cleavage of transfer RNAs (tRNAs).

296 intermediates of yeast and Escherichia coli transfer RNAs (tRNAs).

297 The splicing of two transfer RNAs (trnI-GAU and trnA-UGC) and one ribosomal

298 he inclusion of a disproportionate number of transfer RNAs, which exhibit a conserved secondary struc

299 in synthesis, the ribosome selects aminoacyl-transfer RNAs with anticodons matching the messenger RNA

300 f two basic processes: the aminoacylation of transfer RNAs with their cognate amino acid by the amino