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1 screened, including CD54 (ICAM-1) and CD71 (transferrin receptor).
2 tinol-binding protein (vitamin A), and iron (transferrin receptor).
3 ue and change in plasma ferritin and soluble transferrin receptor.
4 curium-transferrin complexes by the cognate transferrin receptor.
5 d with clathrin and the IR, but not with the transferrin receptor.
6 cycling endosomes positive for Rab11 and the transferrin receptor.
7 cling endosomes, where it interacts with the transferrin receptor.
8 calization of CD44 with the nonraft protein, transferrin receptor.
9 mal markers, but showed coincidence with the transferrin receptor.
10 a non-ER resident type II protein, the human transferrin receptor.
11 with a monoclonal antibody against the mouse transferrin receptor.
12 nds on transferrin-bound iron uptake via the transferrin receptor.
13 were observed for serum ferritin and soluble transferrin receptor.
14 r (CIMPR) without affecting that of TGN46 or transferrin receptor.
15 ermined from hemoglobin, serum ferritin, and transferrin receptor.
16 red in the recycling pathway of the exocytic transferrin receptor.
17 eceptor, while New World arenaviruses hijack transferrin receptor.
18 ed for hemoglobin, serum ferritin, and serum transferrin receptor.
19 nsferrin uptake and lysosomal degradation of transferrin receptors.
20 stitution impairs the endocytic recycling of transferrin receptors.
21 lex class I-like protein that interacts with transferrin receptors.
22 MPO was associated with a lower risk of high transferrin receptor [0.86 (0.74, 0.98)], NEO with a low
25 gested that circulating levels of shed human transferrin receptor 1 (hTfR1) are regulated by PC7.
29 iptionally regulates the iron-uptake protein transferrin receptor 1 (TfR1) and the iron-storage prote
30 enic arenaviruses from South America utilize transferrin receptor 1 (TfR1) as a cellular receptor, th
32 ates entry into grivet and bat cells through transferrin receptor 1 (TfR1) binding but that OCEV glyc
35 ptide ligase, butelase 1, to label the human transferrin receptor 1 (TfR1) in established human cell
40 thogenic arenaviruses of the same clade, use transferrin receptor 1 (TfR1) of their host species to e
42 igh affinity single domain antibodies to the transferrin receptor 1 (TfR1) with efficient biotherapeu
45 T1), the ferritin heavy chain (Fth), and the transferrin receptor 1 (Tfr1), were postnatally ablated
46 The antibody engages the GP1 site that binds transferrin receptor 1 (TfR1)-the host cell surface rece
53 he metabolite stearic acid (C18:0) and human transferrin receptor 1 (TFR1; also known as TFRC) as mit
54 tomography (PET) radiotracer that binds the transferrin receptor 1 (TFRC, CD71) with high avidity.
55 restricted to reticulocytes expressing both transferrin receptor 1 (Trf1 or CD71) and the Duffy anti
56 ransporters mediating placental iron uptake (transferrin receptor 1 [TFR1]) and export (ferroportin [
57 l iron pools and increased the expression of transferrin receptor 1 and iron regulatory protein 2 con
58 were decreased in the epithelial cells, and transferrin receptor 1 distribution was shifted from the
59 k has demonstrated the requirement for human transferrin receptor 1 for virus entry, and the absence
62 rom transferrin without increasing levels of transferrin receptor 1 or the uptake of transferrin.
65 ion of the divalent metal transporter 1, the transferrin receptor 1, and the ferritin heavy chain in
68 rived cell lines through a low-pH-dependent, transferrin receptor 1-independent mechanism, suggesting
71 sing expression cloning, we identified human transferrin receptor-1 (TfR1) as an important receptor f
72 rristatin (NSC30611) acts by down-regulating transferrin receptor-1 (TfR1) via receptor degradation.
73 sion of hepcidin and increased expression of transferrin receptor-1 and erythroferrone, suggesting th
74 egulates iron homeostasis components such as transferrin receptor-1 and ferritin-H in hepatic and ske
77 , divalent metal transporter-1, ferritin and transferrin receptor-1 and greater accumulation of iron.
78 brain is >10-fold greater than antibodies to transferrin receptor-1 and intercellular adhesion molecu
79 fectively depleted cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regu
84 utations in hemochromatosis protein (HFE) or transferrin receptor 2 (TFR2) cause hereditary hemochrom
90 administration or modulating the ability of transferrin receptor 2 [Tfr2] to control red blood cell
91 hereditary hemochromatosis proteins HFE and transferrin receptor 2 may intersect with the BMP pathwa
92 n), HFE (hemochromatosis protein), and TfR2 (transferrin receptor 2), these proteins do not control t
94 (BMP6), hereditary hemochromatosis protein, transferrin receptor 2, matriptase-2, neogenin, BMP rece
95 he hereditary hemochromatosis protein (HFE), transferrin-receptor 2 (TfR2), hemojuvelin, hepcidin, or
96 iron, including HFE and, in rarer instances, transferrin-receptor 2 and hemojuvelin, or make its rece
98 s been associated with mutations in the HFE, transferrin receptor-2 (TfR2), and hemojuvelin (HJV) gen
99 nclude newly identified interactions between transferrin receptor-2 and the erythropoietin receptor.
100 nosome genome contains a family of around 14 transferrin receptors(4), which has been proposed to all
101 .006), a lower mean concentration of soluble transferrin receptor (6.1 compared with 7.8 mg/L, P = 0.
102 tes cellular iron uptake by interacting with transferrin receptor, a crucial protein during erythropo
103 ovary cells with a GFP-tagged transmembrane transferrin receptor, a well-known benchmark of membrane
105 M images identified < or =200 nm clusters of transferrin receptor and clathrin light chain at < or =2
106 nin virus (JUNV) failed to down-regulate the transferrin receptor and did not induce superinfection e
107 determined that CSCs preferentially require transferrin receptor and ferritin, two core iron regulat
109 brogates the somatodendritic polarity of the transferrin receptor and several glutamate receptor type
110 lathrin-mediated internalization of both the transferrin receptor and the beta2 adrenergic receptor.
112 teractions between the basolateral signal of transferrin receptor and the medium subunits of both AP-
113 s) target cerebral endothelial cells through transferrin receptor and the receptor for advanced glyca
114 eceptors and plasma membrane lipids, such as transferrin receptors and sphingomyelin, are delivered t
115 interleukin 2 receptor alpha subunit or Tac, transferrin receptor, and cluster of differentiation 8a,
116 l recycling endosomes positive for Rab11 and transferrin receptor, and CvpA membrane interactions wer
117 alysis was used to determine the presence of transferrin receptor, and ELISA was used to determine to
118 n the aged RPE/choroid, whereas transferrin, transferrin receptor, and ferroportin mRNAs did not chan
120 coexpressing Dendra2-hemagglutinin, PAmKate-transferrin receptor, and PAmCherry1-beta-actin fusion c
121 on and vitamin A biomarkers (ferritin, serum transferrin receptor, and retinol binding protein) in se
122 e binding partners of these deposits (sCD89, transferrin receptor, and transglutaminase 2) decreased
123 ritin, transferrin saturation, serum soluble transferrin receptors, and the serum soluble transferrin
124 ndosomes co-localized with subsets of Rab5-, transferrin receptor-, and Lamp1/Lysotracker-marked comp
126 = 200 nm, height (h) = 200 nm) labeled with transferrin receptor antibody (NP-OKT9) or human transfe
128 nhibit receptor activity simultaneously; and transferrin receptor antibody, to target the tumor vascu
129 leaves unchanged the rate by which MC4R and transferrin receptor are constitutively excluded from th
130 constitutively recycled, HSP90-independent, transferrin receptor are found within modified endosomes
132 rin uptake is due to a decrease in available transferrin receptor at the cell surface, and not to a s
134 approach using expression of a biotinylated transferrin receptor (bTfnR) and controlling its local c
135 ith the endosomal markers including EEA1 and transferrin receptors but also with the TGN marker synta
136 ers and found that the TM motifs of CD40 and transferrin receptor, but not that of CD45, could functi
137 rine brain endothelioma cells overexpressing transferrin receptors, by about 1.4-fold and 2.3-fold co
140 ulating red blood cells were found to retain transferrin receptor (CD71) in their membrane, demonstra
142 /proerythroblast stage, a point at which the transferrin receptor (CD71) is upregulated, iron is impo
143 owever, the selective tropism of P vivax for transferrin receptor (CD71)-positive reticulocytes remai
146 n calculated from serum ferritin and soluble transferrin receptor concentrations allows for the evalu
147 e calculated from serum ferritin and soluble transferrin receptor concentrations, can be used to asse
148 cality of current biomarkers such as soluble transferrin-receptor concentrations and others, and caus
150 otocol makes use of cargo protein (e.g., the transferrin receptor) coupled to a pH-sensitive fluoresc
151 creased early in flight, and transferrin and transferrin receptors decreased later, which indicated t
152 which stalled transit of a1 and transferrin-transferrin receptor, decreased proton efflux, and reduc
153 not contacting transferrin, suggesting that transferrin receptor diversification is driven by a need
154 pe SH3TC2, but not mutant SH3TC2, influences transferrin receptor dynamics, consistent with a functio
155 CD4, the asialoglycoprotein receptor, or the transferrin receptor eliminates intramembrane proteolysi
156 rformed PALM imaging using PAmCherry1-tagged transferrin receptor expressed alone or with photoactiva
158 ginase-1 and YM1 transcription and increased transferrin receptor expression by phagocytic cells.
160 oehner et al. (2014) describe a modular anti-transferrin receptor Fab approach for shuttling therapeu
161 d levels of ferritin and increased levels of transferrin receptor, features characteristic of cellula
162 transferrin receptors, and the serum soluble transferrin receptors-ferritin index are more accurate t
163 ron can effectively reach the brain by using transferrin receptors for crossing the blood-brain barri
165 that mislocalize the dendritic marker human transferrin receptor (hTfR), we found that kinesin heavy
167 Consistent with this, there was stronger transferrin receptor immunoreactivity in the light-expos
168 rmined the structure of a Trypanosoma brucei transferrin receptor in complex with human transferrin,
169 uent delivery into cancer cells, mediated by transferrin receptors, in a complex biological matrix.
170 the protein level, decreased transferrin and transferrin receptor, increased ferritin and ceruloplasm
171 ical early endosomal recycling receptor, the transferrin receptor, indicating that this viral protein
172 pid stress disrupted later steps of MC4R and transferrin receptor internalization to endosomes as wel
173 ugh integrin beta1 endocytosis was impaired, transferrin receptor internalization was unaffected.
175 e for Rabenosyn-5 in determining the fate of transferrin receptors internalized by clathrin-mediated
176 e for the first time that endocytosis of the transferrin receptor is a regulated process that require
177 ereas the CME of constitutively internalized transferrin receptors is mainly dependent on the ubiquit
178 tus (ferritin level, transferrin saturation, transferrin receptor level, reticulocyte hemoglobin leve
179 iron availability, as noted by a decrease in transferrin receptor levels and iron uptake from transfe
180 nd decreased expression of the iron importer transferrin receptor, likely reflecting a regulatory res
181 ) and negatively correlated with the soluble transferrin receptor/log(ferritin) ratio but not correla
182 c characterization, these studies prove that transferrin receptor-mediated endocytosis is a viable me
184 ize, low cellular toxicity and the efficient transferrin receptor-mediated uptake render the AspA tag
190 posomal preparation was also targeted to the transferrin receptor of cancer cells by modifying the su
191 >/=1 biomarker of iron [ferritin or soluble transferrin receptor or vitamin A status (retinol-bindin
193 stricted to this membrane cargo, however, as transferrin receptors packaged in the same population of
194 nnose glycosylation at the helical domain of transferrin receptor protein 1 promotes conformational c
195 chlamydial growth and replication, including transferrin receptor protein 1, the amino acid transport
197 0.22; beta = -0.17 (95% CI: -0.25, -0.09)], transferrin receptor [R(2) = 0.23; beta = 2.79 (95% CI:
198 activating protein for Rab4A that regulates transferrin receptor recycling and EGFR trafficking and
199 , but not the inactive R494A mutant, reduces transferrin receptor recycling but has no effect on tran
200 ation of Bves function specifically inhibits transferrin receptor recycling, and results in gastrulat
201 the modified CLC reduces beta1-integrin and transferrin receptor recycling, as well as cell migratio
204 cysteines 556 and 558 on the surface of the transferrin receptor resulting in subsequent endocytic u
205 biomarkers including serum ferritin, soluble transferrin receptor, retinol-binding protein (RBP), 25-
209 ators serum ferritin <15 ug/L, serum soluble transferrin receptor (sTfR) >4.4 mg/L, and calculated to
210 that is calculated from ferritin and soluble transferrin receptor (sTfR) allows for the evaluation of
211 < or = 0.05), and concentrations of soluble transferrin receptor (sTfR) and hemoglobin and the red c
212 ons.We assessed the relation between soluble transferrin receptor (sTfR) concentrations and inflammat
213 = 0.04) and France (P = 0.04) and on soluble transferrin receptor (sTfR) for participants in Poland (
214 serum ferritin decreased (P < 0.0001), serum transferrin receptor (sTfR) increased (P < 0.0001), and
216 n, ferritin, C-reactive protein, and soluble transferrin receptor (sTfR) strongly predicted incorpora
217 wich assay (SA) for the detection of soluble transferrin receptor (sTfR), a biomarker of IDA, on a ph
218 time, measured by sFer, hemoglobin, soluble transferrin receptor (sTfR), and estimated total body ir
220 rically to include plasma ferritin), soluble transferrin receptor (sTfR), and total body iron (TBI) w
221 line hemoglobin, ferritin, hepcidin, soluble transferrin receptor (sTfR), and transferrin were measur
222 in (SF), transferrin saturation, and soluble transferrin receptor (sTfR), as well as erythrocyte prot
223 timated on the basis of plasma iron, soluble transferrin receptor (sTfR), ferritin, transferrin, tran
224 ess hemoglobin, serum ferritin (SF), soluble transferrin receptor (sTfR), hepcidin, serum iron, eryth
225 iciency, defined by raised levels of soluble transferrin receptor (sTfR), was investigated in 98 pati
226 ) (B = -0.17), hepcidin (B = -0.36), soluble transferrin receptor (sTfR; B = 0.33), and EPO (B = 0.28
228 P]) and biomarkers of MN status (pF, soluble transferrin receptor [sTfR], RBP, and pZn), and compare
230 r trafficking of the endogenously expressing transferrin receptor, suggesting ethanol does not have a
231 followed an innovative approach of combining transferrin receptor targeting with enhanced cell penetr
232 epidermal growth factor receptor (EGFR) and transferrin receptor (TfnR) exhibited changes in steady-
235 t external cues induced up-regulation of the transferrin receptor (TfR) and down-regulation of ferrit
237 tosis, plasma membrane receptors such as the transferrin receptor (TfR) are internalized by a caveola
240 res and impairs recycling of the transferrin-transferrin receptor (TfR) complex to the plasma membran
242 Our results identify a role for PICALM in transferrin receptor (TfR) internalization and demonstra
245 te of iron acquisition in vertebrates is the transferrin receptor (TfR) mediated endocytotic pathway,
249 rom raccoons do not efficiently bind the dog transferrin receptor (TfR) or infect dog cells, a single
252 target a protein complex of transferrin and transferrin receptor (TfR) through a non-canonical allos
253 in the form of tunable nanosystems (NS) for transferrin receptor (TfR) utilizing gambogic acid (GA),
254 , and utilization of a CDP that binds to the transferrin receptor (TfR), a native receptor and BBB tr
255 monoclonal antibody (MAb) against the mouse transferrin receptor (TfR), and these fusion proteins ar
256 monoclonal antibody (MAb) against the mouse transferrin receptor (TfR), and this fusion protein is d
258 Similar to the constitutive endocytosis of transferrin receptor (TfR), ligand- triggered endocytosi
259 g because of the active participation of the transferrin receptor (TFR), salt, a chelator, lobe-lobe
261 monoclonal antibody (MAb) against the mouse transferrin receptor (TfR), which is designated as the c
262 monoclonal antibody (MAb) against the mouse transferrin receptor (TfR), which is designated the cTfR
267 of 3 abnormal ferritin (< 12 mug/L), soluble transferrin receptor (TfR; > 8.3 mg/L), or zinc protopor
268 anine parvovirus (CPV) capsids with cellular transferrin receptors (TfR) on the surfaces of live feli
269 ptake of systemically dosed antibodies (anti-transferrin receptor [TfR] bispecific versus control ant
270 nd significance of positive selection on the transferrin receptor TfR1, a housekeeping protein requir
273 consequence, IRP1 target genes, such as the transferrin receptor (TfR1), a membrane-associated glyco
274 PN), the iron efflux pump, is decreased, and transferrin receptor (TFR1), the iron importer, is incre
275 transmembrane protease, serine 6 (TMPRSS6), transferrin receptor (TFR2), N-acetyltransferase 2 (aryl
276 biquitin C (UBC) in head and neck cancer and Transferrin receptor (TFRC) and beta-Glucuronidase (GUSB
277 y recognized CPV host-to different carnivore transferrin receptors (TfRs) using single-particle track
279 nce of the transferrin moiety binding to the transferrin receptor, the activated ProINS-Tf exhibited
281 0 mg/kg and calculated from the log ratio of transferrin receptor to ferritin (the body iron model) t
284 d an increased dependence of Cd1 GP on human transferrin receptor type 1 (hTfR-1) for entry, which ma
285 ized by different abilities to use the human transferrin receptor type 1 (hTfR1) protein as a recepto
286 ve feline panleukopenia virus (FPV) bind the transferrin receptor type 1 (TfR) to infect their host c
287 300Lys) altered the binding of the capsid to transferrin receptor type 1 (TfR), particularly during v
295 rtantly, the constitutive internalization of transferrin receptors was unaffected by either treatment
296 ed blood cell distribution width and soluble transferrin receptor were elevated (P < 0.05), and serum
297 status biomarkers (ie, ferritin and soluble transferrin receptor) were significantly associated with
298 points, internalized GPR17 co-localized with transferrin receptor, whereas at later times it partiall
299 DNA damage, p53 induced FTH1 and suppressed transferrin receptor, which regulates iron entry into ce
300 tress, including a failure to upregulate the transferrin receptor, which we show is a novel stress ta