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1 phoribulokinase), and part of cbbT (encoding transketolase).
2 tion by ribokinase and further metabolism by transketolase.
3 or substrate binding were examined for human transketolase.
4 vered a mechanism by which null mutations in transketolase A (tktA) and glycerol-3-phosphate (G3P) de
7 crease in the fraction of ribose derived via transketolase, a thiamine-dependent enzyme in the pentos
8 Finally, we propose a two-species model of transketolase activation that describes the interconvers
10 serum and erythrocyte magnesium, erythrocyte transketolase activity (ETKA), lactate dehydrogenase (LD
12 eveal the crucial importance of the level of transketolase activity to provide the precursor for synt
14 m microtubules by washing with salt included transketolase, alpha-enolase, and betaB2-crystallin.
15 ypyruvate (HPA) donor substrate to wild-type transketolase and a variant, S385Y/D469T/R520Q, that is
16 ns with synthesis, by the combined action of transketolase and aldolase, of the seven-carbon bisphosp
18 de in genes encoding phosphoribulokinase and transketolase and in the gene encoding the LysR-type tra
20 PAGE (-DTT) resolved mouse serum albumin and transketolase and indicated that serum albumin was 13% o
21 bears homology to the equivalent domains in transketolase and the E1 subunit of pyruvate dehydrogena
22 abel in the glucose moiety was scrambled via transketolase and transaldolase activities of the pentos
24 n assumptions about the reversibility of the transketolase and transaldolase reactions in the nonoxid
25 represent a novel class of highly conserved transketolases and likely plays a key role in the biosyn
26 etion increased expression of hexokinase II, transketolase, and ribose-5-phosphate isomerase genes in
27 tion factor 2, glucose-regulated protein 78, transketolase, and succinyl-CoA transferase were primari
28 ity again revealed the two distinct forms of transketolase at a TK(high):TK(low) ratio that matched t
29 ent functional pathway that operates through transketolase B (TktB), and which is 'buffered' in wildt
30 Serum albumin from cornea was separated from transketolase by SDS-PAGE (+/-dithiothreitol [DTT]) and
31 ional protein domains was examined using the transketolase C-terminal (TKC)-domain as an example.
32 ced nucleic acid production through impaired transketolase catalysis is the underlying biochemical di
33 mposed of a full-length Arabidopsis thaliana transketolase cDNA under the control of the cauliflower
34 ase multienzyme complex E1 subunit and yeast transketolase crystal structures indicates a general str
37 also known as DHTKD1, dehydrogenase E1, and transketolase domain-containing protein 1) is a thiamin
39 thiamine and benfotiamine therapy increased transketolase expression in renal glomeruli, increased t
43 glucose, fructose induces thiamine-dependent transketolase flux and is preferentially metabolized via
44 or the in vitro determination of activity of transketolase from Escherichia coli (TKec) using commerc
50 histidine is distinct from its role in yeast transketolase in which it aids in binding donor substrat
51 a brief overview of the use of aldolases and transketolases in the synthesis of sugars, sugar analogs
53 and II in the same monomer, whereas that of transketolase is located at the interface of the dimer.
54 i pyruvate dehydrogenase and His263 in yeast transketolase, is on a largely ordered phosphorylation l
56 se) or leucine (the corresponding residue in transketolase) led to greatly diminished kcat values, sh
57 ally, inhibiting the transketolase isoenzyme transketolase-like 1 (TKTL1) by siRNA reversed theses ef
58 e from a YAC in Xp22, the recently described transketolase-like gene in a YAC from Xq28 and a putativ
59 s been associated with overexpression of the transketolase-like-1-gene (TKTL1), which encodes an esse
60 and metabolic enzymes such as transaldolase, transketolase, malate dehydrogenase, asparagine syntheta
61 in M. jannaschii as endoglucanase (MJ0555), transketolase (MJ0681), thiamine biosynthetic protein th
62 tabolic enzymes, including transaldolase and transketolase of the nonoxidative pentose pathway, malat
64 investigate the effect of increased plastid transketolase on photosynthetic capacity and growth, tob
65 active centers of the E. coli E1 subunit and transketolase on the basis of the parallels in the ligat
66 ere complemented by germinating the seeds of transketolase-overexpressing lines in media containing e
67 ls in the seeds and cotyledons were lower in transketolase-overexpressing lines than in wild-type pla
69 led a major and unexpected effect of plastid transketolase overexpression as the transgenic tobacco p
72 versus untreated mice: fatty acid synthase, transketolase, pulmonary surfactant-associated protein C
76 both the pyruvate dehydrogenase complex and transketolase, resulted in enhanced imatinib sensitivity
77 ted to another enzymatic reaction with yeast transketolase that changes the mass of the products to b
78 s is suppressed by overexpression of TKL1, a transketolase that generates NADPH, which balances redox
79 , as we have previously observed for E. coli transketolase, the mutations that improved activity towa
80 drogenase (G6PD) catalyzed oxidative and the transketolase (TK) catalyzed nonoxidative pentose cycle
83 volution of the mechanism and specificity of transketolase (TK) has been minor, and that the smallest
85 d on thiamine pyrophosphate (ThDP)-dependent transketolase (TK)-catalyzed reaction, followed by the o
87 characterised a low-activity form of E. coli transketolase, TK(low), which also binds the cofactor th
88 incident with a more than 90% loss of tissue transketolase (TKT) and aldehyde dehydrogenase (ALDH) cl
89 undantly express two water-soluble proteins, transketolase (TKT) and aldehyde dehydrogenase class 1A1
92 y and Akt association and phosphorylation of transketolase (TKT), a key enzyme of the nonoxidative pe
96 Here, we demonstrate that this protein is transketolase (TKT; EC 2.2.1.1), an enzyme in the nonoxi
97 r two proteins, phosphoglucomutase (Pgm) and transketolase (TktA), are enzymes involved in carbohydra
98 hosphate and triose phosphate and reversible transketolase velocity were similar to net glycolytic fl
99 The S385Y/D469T/R520Q variant of E. coli transketolase was evolved previously with three successi