ライフサイエンスコーパス: transmembrane segment

1 mprising two turns of helix along the fourth transmembrane segment.

2 4A/R5A in the N terminus and F656I in the S6 transmembrane segment.

3 ciated MA-helix that continues into the last transmembrane segment.

4 ion 202, located in the upper side of the S4 transmembrane segment.

5 ut a central residue in the carboxy-terminal transmembrane segment.

6 quence was uncleaved, creating an N-terminal transmembrane segment.

7 n span the OM despite the lack of an obvious transmembrane segment.

8 ng segments and the N-terminal end of the M4 transmembrane segment.

9 ialidases) has a single predicted N-terminal transmembrane segment.

10 Stp1 cleaves Sre1 within its predicted first transmembrane segment.

11 at are permissive for cleavage of one type 2 transmembrane segment.

12 a histidine in the A' helix following the S6 transmembrane segment.

13 nsing and signaling are captured in a single transmembrane segment.

14 nv "spike" and the NMR structure of the MPER-transmembrane segment.

15 n both the absence and presence of the PDGFR transmembrane segment.

16 n with a chloroplast transit peptide and one transmembrane segment.

17 does not form pores, even though it contains transmembrane segments.

18 the cytoplasmic edge of the second and third transmembrane segments.

19 istidine, and an arginine are located in the transmembrane segments.

20 ic subdomains but has not yet been shown for transmembrane segments.

21 d negatively charged residues in neighboring transmembrane segments.

22 ed bacterial Na(+) /H(+) antiporters with 13 transmembrane segments.

23 coding a membrane protein with four putative transmembrane segments.

24 e extracellular loops and outer parts of the transmembrane segments.

25 karyotic GluR subunits (e.g. GluR0) have two transmembrane segments.

26 trands, rigid connectors to their respective transmembrane segments.

27 face of the pore helix 1 (PH1) and S5 and S6 transmembrane segments.

28 ted (125)I, and 17 kDa, containing the M1-M3 transmembrane segments.

29 C-terminus, cytoplasmic loop, and within the transmembrane segments.

30 olesterol may be limited to insertion of the transmembrane segments.

31 second and His-244 and Asp-248 in the fifth transmembrane segments.

32 NBCe1-A transmembrane segment 1 (TM1) is involved in forming par

33 an unexpected role for the highly conserved transmembrane segment 1 residue Asn-101 in coupling Cl(-

34 ss-linker in the matrix exposed loop between transmembrane segments 1 and 2 (loop 1) cross-linked to

35 a bridge between the membrane side of NTSR1 transmembrane segments 1 and 4 and the C-lobe of arresti

36 formed primarily by the cytoplasmic ends of transmembrane segments 1, 2, 6 and 7 as well as intracel

37 ted mutagenesis at highly conserved sites of transmembrane segments 1, 3, 8, 9, and 10, which have be

38 cluster at two interfacial regions flanking transmembrane segments 1-4 and lie outside of the canoni

39 A domain (consisting of transmembrane segments 1-4) that moves during activation

40 id residue at or near a conserved glycine in transmembrane segment 10.

41 residues that line the permeation pathway in transmembrane segment 11 (TM11).

42 the extracellular end of the pore lining M2 transmembrane segment (18').

43 mbrane domains and a helical hairpin between transmembrane segment 2 (TM2) and TM3 on the cytoplasmic

44 erentially induces conformational changes in transmembrane segment 2 and extracellular loop 1 (EL1),

45 An asparagine residue (Asn-106) in transmembrane segment 2 of AHA2 is conserved in all P-ty

46 ed a number of positions in the loop between transmembrane segments 2 (M2) and 3 (M3) of a proton-gat

47 over, we identified two structural motifs in transmembrane segments 2 and 4 involved in mTRPA1-choles

48 s study, we mutated multiple residues within transmembrane segments 2 and 7 of NCX1.1 (cardiac isofor

49 ion shows that the conserved residues within transmembrane segments 2 and 7, coordinating Na(+) and C

50 , located at the predicted interface between transmembrane segment 3 (TMS3) and extracellular loop 2

51 Cldn3/Cldn5 residues in transmembrane segment 3, TM3 (Ala-127/Cys-128, Ser-136/C

52 Transplanting transmembrane segments 3 and 4 (TM3-4) of Drs2 into Dnf1

53 a pocket created by intracellular loop 2 and transmembrane segments 3 and 4, stabilizing the loop in

54 e highly conserved first arginine residue in transmembrane segment 4 (domain 1), the voltage sensor,

55 ed channels, a common feature is shared; the transmembrane segment 4 (S4) contains positively charged

56 cytoplasmic domain of FlhA, located between transmembrane segments 4 and 5.

57 o the L1 loop and the periplasmic portion of transmembrane segments 4-6.

58 bule closed and the intracellular portion of transmembrane segment 5 (TM5i) in either an unwound or a

59 on network leading to a discrete rotation of transmembrane segment 5 and the adjacent intracellular l

60 We have previously identified Ser293 in transmembrane segment 5 as a determinant for selective K

61 sed water exposure of the cytoplasmic end of transmembrane segment 5.

62 results show that conformational changes in transmembrane segments 5 and 6 (TM5 and TM6), which are

63 through a four-helix bundle motif formed by transmembrane segments 5 and 6.

64 ated in the large intracellular loop between transmembrane segments 5 and 6.

65 ansmembrane segment 6, and rearrangements of transmembrane segments 5 and 7 that are remarkably simil

66 metry around a central ion pathway formed by transmembrane segments 5-6 (S5-S6) and the intervening p

67 ive exons 8a and 8 encode alternate forms of transmembrane segment 6 (IS6) in channel domain 1.

68 A outward movement at the cytoplasmic end of transmembrane segment 6 (TM6) and an alpha-helical exten

69 Met-Gly (GMG) motif in the unwound region of transmembrane segment 6 (TM6) is central for the recogni

70 es reveal a disruption in the alpha-helix of transmembrane segment 6 (TM6) not observed in family A G

71 erved residues, including two histidines, of transmembrane segment 6 (TMS-6).

72 A outward movement of the cytoplasmic end of transmembrane segment 6, and rearrangements of transmemb

73 ituting each successive residue in predicted transmembrane segment 9 with a cysteine residue.

74 RibU contains six transmembrane segments, adopts a previously unreported t

75 with two bound phospholipids located between transmembrane segments alphaTM8-10 and TMFXYD (site A) a

76 companion article, we showed that the single transmembrane segment ancillary (beta) subunits KCNE1 an

77 -harvesting complex-binding motif within the transmembrane segment and a large surface-exposed head d

78 SpoIIIAH consists of a transmembrane segment and an extracellular domain with s

79 olytic fragments of 8 kDa, containing the M4 transmembrane segment and approximately 60% of incorpora

80 surrounding the extracellular end of the M2 transmembrane segment and around the loop connecting the

81 first domain present downstream of the sixth transmembrane segment and connects the CNBD to the trans

82 rane domain, which include bending of the S6 transmembrane segment and consequent pore dilation, disp

83 in a hydrophobic pocket at the end of the S6 transmembrane segment and is involved in inter-subunit i

84 omains via concerted movements of the second transmembrane segment and major coupling helix.

85 ng domain (VSD) of Kv1.3 through W172 in the transmembrane segment and modifies the gating operation.

86 , juxtaposed between residues on the KCNQ S5 transmembrane segment and S4-5 linker.

87 latelet-directed growth factor receptor beta transmembrane segment and the bilayer thickness.

88 ontain a transmembrane domain (TMD) with six transmembrane segments and a nucleotide-binding domain (

89 llular space and are initially linked by two transmembrane segments and a single cytoplasmic domain.

90 rough a control cable connection between the transmembrane segments and AS1 helices.

91 main that is anchored in the membrane by two transmembrane segments and belongs to the dCache superfa

92 They share four predicted core transmembrane segments and possess similar yet distinct

93 vised topology confirms the presence of four transmembrane segments and reveals a newly identified pe

94 s truncation mutant comprising the last five transmembrane segments and the intracellular C-terminus

95 itioned at three-residue intervals in the S4 transmembrane segment, and this movement is coupled to o

96 ted domain and the hydrophobicity within the transmembrane segment are important determinants of the

97 translation terminates before emergence of a transmembrane segment are translated in the stroma and t

98 These transmembrane segments are driven outward by the force o

99 inker of Eag1 is a five-residue loop and the transmembrane segments are not domain swapped, which sug

100 ptor residue Tyr(145), adjacent to the first transmembrane segment, as the site of labeling by the po

101 receptor function through interactions with transmembrane segments, as well as through peripheral in

102 g causes changes in the relative position of transmembrane segments both within a single subunit and

103 ion of sdp of a truncated KinD retaining the transmembrane segments but lacking the kinase domain.

104 outward movement of gating charges in the S4 transmembrane segments catalyzed by sequential formation

105 difficult-to-overexpress members of the six-transmembrane segment channel family.

106 second and His-153 and Asp-157 in the fifth transmembrane segments coordinate zinc and are required

107 ied by azobenzene-containing reagents at the transmembrane segments could be reversibly turned on and

108 ducting channels that facilitate movement of transmembrane segments, cytosolic and luminal funnels in

109 cause insertion of an artificial polyleucine transmembrane segment does not rescue surface expression

110 ar dynamics simulations of different nascent transmembrane segments embedded in a ribosome-bound bact

111 Here, using model transmembrane segments engineered into m-AAA protease-de

112 Members of the six-transmembrane segment family of ion channels share a com

113 Each Hrd1 molecule has eight transmembrane segments, five of which form an aqueous ca

114 pectroscopic measurements indicate its first transmembrane segment folds into an alpha-helix, in agre

115 alf contains a transmembrane domain with six transmembrane segments followed by a nucleotide-binding

116 ain starts with a short loop after the third transmembrane segment, followed by a short alpha-helical

117 tinating enzyme that requires its N-terminal transmembrane segment for activity towards Hrd1.

118 led the ligand-binding domains from specific transmembrane segments for GluN1 and GluN2A.

119 pneumophila Cu(+)-ATPase shows that a kinked transmembrane segment forms a "platform" exposed to the

120 rved regions and helical exchange within the transmembrane segments, forms three channels occupied by

121 rs can, and have to, dissociate to leave the transmembrane segments free to deploy and lead to pore f

122 r cavity, which is formed jointly by four S6 transmembrane segments from domains D1 to D4.

123 f detergents surrounding LeuT protecting its transmembrane segments from unfavorable hydrophobic/hydr

124 sults indicate that amino acids from several transmembrane segments functionally cooperate to form a

125 These results indicate that the first transmembrane segment generally comprises the signal tha

126 vation to channel gating, the pore-lining S6 transmembrane segment has not been systematically studie

127 y disease proteins and it precedes the first transmembrane segment in both families.

128 We determined the structure of the transmembrane segment in dodecylphosphocholine micelles

129 Deletion of a transmembrane segment in the beta-subunit results in mis

130 hed ribosomes occurs shortly after the first transmembrane segment in the nascent peptide has emerged

131 , which is consistent with the presence of a transmembrane segment in their C-terminal regions.

132 utward movement of the positively charged S4 transmembrane segment in their voltage sensors.

133 The results further define the borders of transmembrane segments in subunit a.

134 llular unstructured region linking the S5-S6 transmembrane segments in the DII domain of the human Na

135 of conserved acidic side chains on the S1-S3 transmembrane segments in the hydrated interior of the V

136 hreshold hydrophobicity for the retention of transmembrane segments in the inner membrane is differen

137 ic loops in the C-terminal half of Sec61 and transmembrane segments in the N-terminal half of the Sec

138 annel (VGIC) superfamily members contain six-transmembrane segments in which the first four form a vo

139 nents, especially the loops that connect the transmembrane segments, in the assembly and function of

140 of an SRP-RNC complex exposing a hydrophobic transmembrane segment induces a rearrangement of the Sec

141 hly conserved asparagine (N220) in the first transmembrane segment is a key enforcer of glycerophosph

142 The lipid/aqueous interface of the last transmembrane segment is at Asp(960).

143 n that connects ankyrin repeats to the first transmembrane segment is crucial for temperature sensing

144 l/functional significance of this additional transmembrane segment is poorly defined.

145 asmic domain or if the hydrophobicity of the transmembrane segment is reduced by substituting polar r

146 GluN1 subunits at the entrance of the first transmembrane segment is shorter and the bilobed cleft o

147 uble domain and that the interaction between transmembrane segments is highly dynamic.

148 aptation, and its quantification at specific transmembrane segments is shown to predict favorable con

149 FtsW (this protein consists of 10 predicted transmembrane segments) is required for the transport ac

150 This motif, lying close to the S1 transmembrane segment, is situated near the T1 tetrameri

151 008 possible ectodomains and two alternative transmembrane segments, it may carry endodomains contain

152 examined the role of amino acid residues of transmembrane segment IV (TM IV) ((126)FPQINFLGSLLIAGCIT

153 sensor histidine kinase BovK contains eight transmembrane segments lacking any extensive surface-exp

154 ragment comprising the ER-lumenal domain and transmembrane segment (LDTM).

155 X appeared collapsed against the hydrophobic transmembrane segments, leading to an aberrant topology

156 lipid head group in a groove outlined by the transmembrane segments M1, M2, M4, and M6, with the hydr

157 robed the conformation of pore-lining second transmembrane segment (M2) under conditions that favor t

158 ear the intracellular end of the pore-lining transmembrane segments (M2) that are also required to ac

159 The SLN pentamer was found to interact with transmembrane segment M3 of SERCA, although the interact

160 lar domain (ICD) present in metazoa (between transmembrane segments M3 and M4).

161 e 2D crystals, a PLN pentamer interacts with transmembrane segments M3 of SERCA and participates in a

162 ted the importance of amino acid residues in transmembrane segment M4 of mammalian P4-ATPase ATP8A2 b

163 ontrast, eukaryotic GluRs have an additional transmembrane segment (M4), located C-terminal to the io

164 Hence, Lys(873), located in transmembrane segment M5 at a "hot spot" for cation bind

165 is located in the intracellular loop between transmembrane segments M8 and M9.

166 idues in cytoplasmic loops connecting distal transmembrane segments mediate calcium stimulation.

167 as a helical hairpin, i.e., the prospective transmembrane segment moves along the YidC greasy slide

168 gy analysis revealed that FtsX has only four transmembrane segments, none of which contains a charged

169 f the cytoplasmic domain, which leads to the transmembrane segment not present in the crystal structu

170 ane proteolysis (RIP) involves cleavage of a transmembrane segment of a protein, releasing the active

171 ane proteolysis (RIP) involves cleavage of a transmembrane segment of a protein.

172 of positively charged amino acids in the S4 transmembrane segment of a voltage-gated ion channel for

173 ted at a conserved distance before the first transmembrane segment of both Sre1 and Sre2 and cleavage

174 of p85, between the GPS domain and the first transmembrane segment of CIRL.

175 light the importance of both calcium and the transmembrane segment of L-selectin in the interaction b

176 hand, when E5 was co-reconstituted with the transmembrane segment of PDGFR, it was able to tolerate

177 is incompatibility is localized to the first transmembrane segment of SSP (TM1).

178 in the N terminus and the other in the first transmembrane segment of the beta1 and beta4 subunits.

179 e of the second extracellular loop and fifth transmembrane segment of the D2R.

180 allization of a peptide corresponding to the transmembrane segment of the influenza M2 protein.

181 erved active-site Lys residue in the seventh transmembrane segment of the protein.

182 ophobic amino acid residues within the first transmembrane segment of the S units for S unit/T unit i

183 e, Golgi-localized protease that cleaves the transmembrane segment of the TatA rhomboid model substra

184 es showed that the mutation H22A, within the transmembrane segment of TolA, abolishes immunity protei

185 dentified a point mutation (N855S) in the S4 transmembrane segment of TRPA1, a key sensor for environ

186 Finally, we identified mutations in the transmembrane segment of YneA that abolish the ability o

187 serine binding site has been located between transmembrane segments of alphaTM8-10 and the FXYD prote

188 o(707) (HM-loop) that connects the first two transmembrane segments of ATP7A is important for copper

189 The transmembrane segments of CD81 pack as two largely separ

190 All 12 of the predicted transmembrane segments of Glut1 encompassing 252 amino a

191 tify residues in the extracellular loops and transmembrane segments of hERG1 that might interact with

192 er ERAD components, requires the presence of transmembrane segments of Hrd1p, and depends on both the

193 conserved hydrophobic amino acids in the S3b transmembrane segments of Kv4.3 and the closely related

194 monstrates that YidC interacts with multiple transmembrane segments of LacY during membrane biogenesi

195 After threading into the SecYEG translocon, transmembrane segments of nascent proteins are thought t

196 tracellular" facing regions of the S2 and S3 transmembrane segments of Nav1.3 and Nav1.7 seem to be m

197 nd that increasing the hydrophobicity of the transmembrane segments of PClep can decrease the translo

198 cellular loops between the sixth and seventh transmembrane segments of PKD1 and PKD1L3, respectively.

199 The transmembrane segments of RHD3 are essential for targeti

200 nker) between the third (S3) and fourth (S4) transmembrane segments of the VSD alters the equilibrium

201 ind that the extracellular ends of the first transmembrane segments of the VSDs form the intersubunit

202 cation mutant of CFTR missing the first four transmembrane segments of TMD1, Delta264 CFTR, binds to

203 acellular loops between the first and second transmembrane segments of TRPP2 and TRPP3 associate with

204 conserved positively charged residue within transmembrane segment one (at position 72) is located in

205 g identified receptor residue Leu(141) above transmembrane segment one as its site of labeling for th

206 eaving membrane-associated proteins within a transmembrane segment or at a site near the membrane sur

207 se processes by cleaving substrates within a transmembrane segment or near the membrane surface.

208 either via an annular layer surrounding the transmembrane segments or by specific lipid-protein inte

209 demonstrates that HiGlpG, with a simple six-transmembrane-segment organization, is more robust than

210 els are membrane proteins that consist of 24 transmembrane segments organized into four homologous do

211 iar in that more gating charge is carried by transmembrane segments other than S4.

212 maritima CorA shows a homopentamer with two transmembrane segments per monomer connected by a short

213 an extended allosteric interface between the transmembrane segments performing the large scale confor

214 tional annotations such as domain detection, transmembrane segment prediction, and calculation of ami

215 s unstable insertion of the eighth and final transmembrane segment, preventing proper position of the

216 c-epitopes we show that forces acting on the transmembrane segment produce loose clusters, while cyto

217 Fusion of a FLAG-tagged one-transmembrane segment protein Tac to the SERT N terminus

218 exposing 'masked' conformational dynamics of transmembrane segments rather than sequence-specific bin

219 first example of a naturally occurring seven-transmembrane segment receptor that is both obligately u

220 ylatoxin functions by interacting with two 7-transmembrane segment receptors, the C5aR and C5L2.

221 We report that the N terminus plus the first transmembrane segment (residues 1-153) is sufficient to

222 ract predominantly with sites located in the transmembrane segments, resulting in nativelike complexe

223 channels, we identify a region encompassing transmembrane segments S1, S2, and S3 in the second homo

224 gatively charged residues distributed in the transmembrane segments S1, S2, and S3 that bind to and f

225 ed mutations have been reported in the first transmembrane segment (S1) of Kv11.1 channels, but the r

226 nserved protein modules that consist of four transmembrane segments (S1-S4) and confer voltage sensit

227 tage-gated potassium channel subunit has six transmembrane segments (S1-S6) to form the voltage-sensi

228 Each monomer/domain contains six transmembrane segments (S1-S6), S1-S4 being the voltage-

229 VSDs consist of four transmembrane segments, S1-S4, forming an antiparallel h

230 We chose the second transmembrane segment, S2, of a voltage-gated potassium

231 In long-QT syndrome, transmembrane segments S3-S5+S6 and the DIII/DIV linker

232 at includes the C-terminal part of the third transmembrane segment (S3b) and the N-terminal part of t

233 re positively charged residues in the fourth transmembrane segment (S4) sense the potential.

234 , using 2 gating charges found in its fourth transmembrane segment (S4) to control its conductive sta

235 9, which codes for the linker connecting the transmembrane segment S6 and the cytosolic RCK1 domain--

236 smFRET on the transmembrane segments shows that they are tightly coupl

237 to the highly conserved homologous S3 and S4 transmembrane segments, suggesting a shared mechanism of

238 ind that a protein with a highly hydrophobic transmembrane segment that inserts into the membrane by

239 om biochemical analysis reveals three common transmembrane segments that are similarly arranged aroun

240 oltage-sensor domains (VSDs) are specialized transmembrane segments that confer voltage sensitivity t

241 lar elements involved in GABA binding to the transmembrane segments that control the opening of the i

242 rokaryotic iGluR subunits have an additional transmembrane segment, the M4 segment, which positions t

243 closed state by acting as wedges between the transmembrane segments, thereby preventing gating rearra

244 obust than PsAarA, which has seven predicted transmembrane segments, thus rendering HiGlpG amenable t

245 s bridge, between residues E(90) [located in transmembrane segment (TM) 2] and K(121) (TM3), is assoc

246 f CCK1R exon 3, extending from the bottom of transmembrane segment (TM) 3 to the top of TM5, includin

247 ls a major tilting of the cytoplasmic end of transmembrane segment (TM) 5, which, together with relea

248 agent, we tested the effects of mutations at transmembrane segment (TM) 6 and 12 helices in HEK293 ce

249 ach located at the centre of a distinct four transmembrane segment (TM) bundle.

250 (Spf1 in yeast) directly interacted with the transmembrane segment (TM) of mitochondrial tail-anchore

251 itors in the presence of Basigin-2, a single transmembrane segment (TM)-containing chaperon.

252 idues located at the C terminus of the first transmembrane segment (TM-1) are important structural co

253 P(1B)-type ATPases have six or eight transmembrane segments (TM) with metal coordinating amin

254 inge, the conserved Gly-98 site in the first transmembrane segment (TM1) of Orai1.

255 hydrophobicity of key residues in the first transmembrane segment (TM1).

256 utations at two conserved sites in the first transmembrane segment (TM1): arginine 91 located near th

257 on of the extracellular ligand binding loop, transmembrane segments (TM1 and TM2), and intracellular

258 The enzyme contains ten transmembrane segments (TM1-10).

259 units in the membrane domain and bears three transmembrane segments (TM1-3).

260 SERCA2a and SERCA1a, SERCA2b houses an 11th transmembrane segment (TM11) and a short luminal extensi

261 he central glycine in the pore-lining second transmembrane segment (TM2) to proline in Kir6.2 causes

262 The sixth transmembrane segment (TM6) of the CFTR chloride channel

263 ins that occurred soon after a nascent chain transmembrane segment (TMS) entered the ribosomal tunnel

264 posure is switched after a newly synthesized transmembrane segment (TMS) enters the ribosomal tunnel.

265 Solute carrier 11 (Slc11) family, such as 12-transmembrane segment (TMS) topology (N- and C-termini c

266 e binding site at the cytosolic interface of transmembrane segments (TMs) 3-5.

267 NPC1 contains 13 transmembrane segments (TMs) and three distinct lumenal

268 g cassette (ABC) proteins, is composed of 12 transmembrane segments (TMS) and two large cytoplasmic n

269 gh these studies also identified a number of transmembrane segments (TMs) as pore-lining, the exact l

270 Whereas the core transmembrane segments (TMs) of SSSs share high structur

271 aped transmembrane domain, which contains 19 transmembrane segments (TMs), and a large extracellular

272 in of DsbD (DsbDbeta), which comprises eight transmembrane segments (TMs), contains two redox-active

273 TR) chloride channel have identified several transmembrane segments (TMs), including TM1, 3, 6, 9, an

274 Each protomer comprises six transmembrane segments (TMs), with TM3 and TM4 contribut

275 release-activated Ca(2+) channels, has four transmembrane segments (TMs).

276 transmembrane region of NBCe1-A contains 14 transmembrane segments (TMs).

277 ed within a major substrate binding site, in transmembrane segments TMS1, TMS3, TMS6 and TMS8.

278 e translocon, where nonpolar nascent protein transmembrane segments (TMSs) are widely believed to par

279 tagenesis of the primary sequences of the 12 transmembrane segments (TMSs) found in the TMDs.

280 The topological model is comprised of nine transmembrane segments (TMSs).

281 By attaching an extra transmembrane segment to the N terminus of SpoIVFB, expr

282 is composed of claudins that consist of four transmembrane segments, two extracellular segments (ECS1

283 change toward the ligand-binding domain and transmembrane segments, ultimately inhibiting the channe

284 n the first alpha-helical turn of the second transmembrane segments underlie this phenomenon and that

285 main (CNBD) connected to the pore-forming S6 transmembrane segment via the C-linker.

286 other proteins indicated that the N-terminal transmembrane segment was responsible for EFC interactio

287 48 in the first (Glu-25) or fourth (Asn-127) transmembrane segments were required.

288 med with the full-length protein or with the transmembrane segments were used along with in vivo homo

289 e of DsbB, one located between the two first transmembrane segments where the quinone ring binds and

290 by interactions between the second and third transmembrane segments, which affect the ion channel lum

291 Each subunit is composed of two transmembrane segments, which are linked by a large extr

292 Each protomer consists of nine transmembrane segments, which enclose a cytosolic tunnel

293 or, but simply surrounding the chemoreceptor transmembrane segment with a lipid bilayer was not suffi

294 x switch involving interaction of its second transmembrane segment with one or more cytochromes under

295 s a quinone, connected through an additional transmembrane segment with the periplasmic thioredoxin-l

296 ed that the C terminus of NBCe1-A contains 5 transmembrane segments with greater average size compare

297 s numerous mutations are tolerated in the E5 transmembrane segment, with the exception of one hydroge

298 nteract via association of the C-terminal or transmembrane segments, with consequences for the assemb

299 The intracellular aspect of the sixth transmembrane segment within the ion-permeating pore is

300 no group of G444, capping the alpha-helix of transmembrane segment XII and thus stabilizing the struc