ライフサイエンスコーパス: transport mechanism

1 and apoptosis, independent of the morphogen transport mechanism.

2 iffusion was shown to be the only prevailing transport mechanism.

3 figures the TMD, two critical aspects of Pgp transport mechanism.

4 with time, providing evidence for an active transport mechanism.

5 ith quantum mechanical tunneling as dominant transport mechanism.

6 rovide insight on the charge storage and ion transport mechanism.

7 FSD2A harbors unique structural features and transport mechanism.

8 GlcP(Se) and crucial for the glucose/H(+) co-transport mechanism.

9 nrecognized rate-limiting barrier in the NSS transport mechanism.

10 this interaction is a central aspect of the transport mechanism.

11 ormational changes that are critical for the transport mechanism.

12 or investigating the protein's structure and transport mechanism.

13 ynaptic membrane without requiring an active transport mechanism.

14 from symbiont commensals represent one such transport mechanism.

15 to employ a diffusion-based, entropy-driven transport mechanism.

16 g an essential function for this loop in the transport mechanism.

17 transition and shedding light on the proton-transport mechanism.

18 nfirming an important aspect of the proposed transport mechanism.

19 IA penetrated into the brain by a saturable transport mechanism.

20 of IFN-alpha, but by a facilitated saturable transport mechanism.

21 structural aspects of PINs related to their transport mechanism.

22 few studies document the flow to provide the transport mechanism.

23 butes to the neuroinvasive retrograde axonal transport mechanism.

24 d in computational studies to understand the transport mechanism.

25 elucidate its possible function in the lipid transport mechanism.

26 has been extensively used to understand the transport mechanism.

27 Our findings shed light on the LPS transport mechanism.

28 ed to this tunnel supporting a proton-driven transport mechanism.

29 (FG nups), that play the key role in the NPC transport mechanism.

30 that exchange of S-components is part of the transport mechanism.

31 d speculation that flippases use a different transport mechanism.

32 ctrode Fermi level) suggests a LUMO mediated transport mechanism.

33 itical for elucidating the bacterial protein transport mechanism.

34 at ciliary transport is analogous to nuclear transport mechanisms.

35 en constructed to explore the underlying ion transport mechanisms.

36 en implicate mitochondrial dynamics and axon transport mechanisms.

37 in compliance, and newly characterised water-transport mechanisms.

38 or the early evolution of microbial electron transport mechanisms.

39 ant kinetic and thermodynamic differences in transport mechanisms.

40 ortant for cancer cell regulation of lactate transport mechanisms.

41 stood, much less is known about TIA membrane transport mechanisms.

42 -length MerF provides insights into possible transport mechanisms.

43 linity can give insight into molecular-level transport mechanisms.

44 ne nucleotides [NAD(P)(H)] also regulate ion transport mechanisms.

45 requires sorting signals as well as specific transport mechanisms.

46 al and theoretical analyses of intracellular transport mechanisms.

47 e determination of other biological actinide transport mechanisms.

48 d define a role for CvpA in subverting these transport mechanisms.

49 s, unanswered questions remain regarding the transport mechanisms.

50 ossess distinctive features of catalytic and transport mechanisms.

51 on and make it available to cells via active transport mechanisms.

52 PA films because of the transition in water transport mechanisms.

53 implement insights into many other cellular transport mechanisms.

54 t modulates the rate-limiting aspects of the transport mechanism(4,5), including the rate at which th

55 These principles of exchange and transport mechanisms across the mitochondrial membrane a

56 d their bacterial counterparts differ in the transport mechanism, adopting uniport and sugar/H(+) sym

57 the most thorough understanding of the O(2-) transport mechanism along the channels to date, clarifie

58 pair of the CT state undergoes a stretching transport mechanism analogous to an 'inchworm' motion, i

59 es of Peppas equation explains a non Fickian transport mechanism and diffusion or diffusion-swelling

60 e fetus transplacentally by an active biotin-transport mechanism and is critical for fetal developmen

61 t review describes the structure, evolution, transport mechanism and physiological functions of SWEET

62 provides key information for elucidating the transport mechanism and predicts candidate substrate bin

63 has gained very significant insight on their transport mechanism and regulation.

64 y of organic electronics promises new charge transport mechanism and specific molecular recognition w

65 ave been extensively studied with respect to transport mechanism and structure-function relationships

66 highly attractive model systems to study ion-transport mechanisms and could potentially be of high th

67 functions of mRNA levels for a wide range of transport mechanisms and find that in the limit of small

68 t in DNA is important for unravelling charge transport mechanisms and for developing relevant applica

69 Contributions of gas transport mechanisms and fracture complexity to well pro

70 This Review is focused on ion-transport mechanisms and fundamental properties of solid

71 structural components, regulated by nuclear transport mechanisms and host factor binding.

72 rtant for elucidating the fundamental charge transport mechanisms and intrinsic mobility in organic s

73 The major ion transport mechanisms and ion channels that are involved

74 marily on new insights into osmotic membrane transport mechanisms and on novel membranes and draw sol

75 This study shows that nonvesicular sterol transport mechanisms and STARD4 in particular account fo

76 However, the membrane transport mechanisms and the signaling events involved i

77 redox probes is key to understanding charge transport mechanisms and to the design of bioelectronic

78 , and atmospheric nuclear tests for (129)I), transport mechanisms, and fallout patterns.

79 We identify the microscopic transport mechanisms, and find facile vacancy-assisted m

80 including signaling, cellular organization, transport mechanisms, and more.

81 f their chemical transformations, uptake and transport mechanisms, and phytotoxic impacts is still la

82 ng to its long neuron-like hyphae, conserved transport mechanisms, and powerful genetics.

83 i with respect to kinetics, energy coupling, transport mechanisms, and substrate specificity.

84 ial Ca(2+) concentrations, identification of transport mechanisms, and the proximity of mitochondria

85 Alternate maternofetal transport mechanisms appear to provide adequate B12 to t

86 completely understood, insofar as no single transport mechanism appears to account for all of the ob

87 tive contribution and spatial routes of each transport mechanism are largely unknown.

88 Major impediments to understand the transport mechanism are the thousands of FG binding site

89 Motor-based transport mechanisms are critical for a wide range of eu

90 rve terminals are 5-7 mm, and that vesicular transport mechanisms are not saturated under basal condi

91 Therefore, transport mechanisms are required to mediate the movemen

92 biogeochemical cycling, efficient off-shelf transport mechanisms are required.

93 and mobilities have not been determined and transport mechanisms are still a matter of guesswork.

94 sidues will improve the understanding of the transport mechanism, as well as allow comparative studie

95 ions provide atomic detail insights into the transport mechanisms, as well as converged kinetics and

96 Currently accepted transport mechanisms assume that Na(+) and K(+) effects

97 Here we describe the urea transport mechanism at atomic resolution, revealed by un

98 ntribute to a better understanding of proton-transport mechanisms at weakly polar surfaces and near p

99 TMD-NBD cross-talk is a key step in the transport mechanism because drug binding stimulates ATP

100 a also describe marked redundancy within the transport mechanism, because single-Q-loop mutants are f

101 y represents a fundamental difference in the transport mechanism between ABC exporters and ABC import

102 These observations demonstrate a novel transport mechanism between photoreceptor cells and RPE

103 Oxygen transport mechanisms between gas-surface reactions and s

104 binding domains (NBDs) is fundamental to the transport mechanism, but is poorly understood at the bio

105 nula occludens-1 (PDZ) domains to engage the transport mechanism, but with the PDZ domains deleted, b

106 rate selectivity and the Na(+)-coupled anion transport mechanism by the human SLC13 family and other

107 ct epithelium was developed to determine the transport mechanism by which HCO3(-) ions are secreted a

108 These findings support a novel transport mechanism by which lysophosphatidylcholines ar

109 However, the transport mechanisms by which these lipids reach the myc

110 This finding is a new long-range transport mechanism comparing to the well-established me

111 mT, these observations indicated a saturable transport mechanism consistent with carrier/receptor-med

112 Intramuscular signaling and glucose transport mechanisms contribute to improvements in insul

113 get deeper insight into the underlying mass transport mechanisms controlling drug release from coate

114 esign concepts, electronic structure, charge transport mechanisms, defect states, thin-film processin

115 on to investigate the metabolic pathways and transport mechanisms driving moist acidic tundra CH4 flu

116 a full understanding of the thermal and mass transport mechanisms during DWC processes.

117 his analysis demonstrated that the different transport mechanisms either had a size dependent mobilit

118 The EOF transport mechanism enables highly sensitive detection o

119 This efficient energy transport mechanism enables the allosteric propagation o

120 By means of this delayed ocean transport mechanism, ENSO provides an additional heat su

121 ion of floc from SML biofilms, identifying a transport mechanism entraining SML accumulated microorga

122 However, understanding of the transport mechanism, especially of human ABC exporters,

123 al indicating that alternative ascorbic acid transport mechanisms exist.

124 ed substrate dependences of MjNhaP1, and the transport mechanism explains alkaline down-regulation of

125 ugh lipid membranes, while most known active transport mechanisms facilitate cell uptake of only very

126 This work describes a unique transport mechanism for a P-type ATPase and provides ins

127 as inhibited, suggesting a retrograde axonal transport mechanism for delivery into the CNS.

128 It is the primary transport mechanism for heat and chemical species and th

129 ceptor (FcRn) was originally discovered as a transport mechanism for IgG from maternal circulation to

130 is, unfortunately, an extremely inefficient transport mechanism for microscale particles.

131 -binding site, and suggest a structure-based transport mechanism for the ZIP2 transporter.

132 e measurements reveal a new singlet-mediated transport mechanism for triplets, which leads to an enha

133 ical approach provides novel insights on oil transport mechanisms from deep blowouts and on gauging t

134 al NSS protein, LeuT, and thus the principal transport mechanism, has been heavily debated.

135 However, dynamic studies of the transport mechanism have been sparse and indirect.

136 Although most of the transport mechanisms have been discovered at the molecul

137 The feasible transport mechanisms have been generally accounted for o

138 ails of structure-function relationships and transport mechanisms have been lacking.

139 Although divergent transport mechanisms have been proposed for these transp

140 Various hopping and mobility edge transport mechanisms have been proposed, but their exper

141 sceptor in Saccharomyces cerevisiae Although transport mechanisms have been suggested for other MFS m

142 n achieve high thermal conductivity, but the transport mechanisms have yet to be elucidated.

143 of guanine bases in the most widely proposed transport mechanism (hopping from guanine to guanine thr

144 n is more complex, given passive and carrier transport mechanisms; however, notable patterns of behav

145 The transport mechanisms identified followed a spatial depen

146 ability of actin monomers, suggest an active transport mechanism in both directions.

147 proteoliposomes, the structures explain the transport mechanism in detail.

148 tion, these results support an elevator-type transport mechanism in EIIC.

149 structures allow us to model a potential ion transport mechanism in KCCs and provide a blueprint for

150 As a result, the intrinsic charge transport mechanism in molecular junction set-ups is not

151 very provides further insights of the charge transport mechanism in perovskite-based optoelectronic d

152 together, our results identified a new iron transport mechanism in plants that could play a major ro

153 Here we provide new insights into the charge-transport mechanism in semiconducting polymers and offer

154 In order to fully understand the lithium-ion transport mechanism in solid electrolytes for batteries,

155 ut it has proved difficult to understand the transport mechanism in the absence of a structure in the

156 knowledge, a detailed picture of the proton transport mechanism in the central region of ClC-ec1 at

157 ependent conductance showed that the carrier transport mechanism in the GG was thermal excitation, wh

158 characteristics enable a rapid and specific transport mechanism in the physiological context, a noti

159 d understanding of substrate recognition and transport mechanism in the SLC1 family.

160 nergy loss rules out coherent tunneling as a transport mechanism in the thicker films and provides a

161 Yet, the nature of charge carriers and their transport mechanism in these materials is still unclear.

162 troscopies supports a core/shell two-channel transport mechanism in this type of solar cells and furt

163 diffusion of bulky molecules via an elegant transport mechanism in which a mobile element formed by

164 cation could be achieved by an elevator-type transport mechanism in which a transport domain binds to

165 e transporter families all share an elevator transport mechanism in which alternating access is provi

166 Together, these results support a transport mechanism in which the ATP-driven movements of

167 A proton transport mechanism in which the channel, depending on p

168 ons provide insights into macroscopic charge transport mechanisms in conjugated polymers and suggest

169 and provide insights into systems-level salt transport mechanisms in intact plants.

170 d indicate that inclusion of plant hydraulic transport mechanisms in models may be critical for accur

171 y provides essential insight into the charge transport mechanisms in organic semiconductors.

172 ity of information that exists regarding ion transport mechanisms in prokaryotes.

173 g of the highly regulated membrane and cargo transport mechanisms in relation to polysaccharide depos

174 tes plant development, but the role of auxin transport mechanisms in the context of land plant evolut

175 n diffusion always plays a role on shale gas transport mechanisms in the reconstructed shales.

176 ctural elements previously implicated in the transport mechanism, in particular transmembrane helices

177 structure is essential to understanding the transport mechanism including the critical determinants

178 ted these experimental findings in a revised transport mechanism, including the K(+)/Na(+) co-binding

179 The proposed transport mechanism inherently down-regulates Na(+)/H(+)

180 was found for [(18)F]5, indicating no active transport mechanism into cells.

181 fundamental insights into the formation and transport mechanisms involved in solid-filler incorporat

182 scanning microscopy, we have identified the transport mechanisms involved in the detrimental focal s

183 om Vibrio cholerae, predict an elevator-like transport mechanism involving a large rigid body movemen

184 r lipids, selected tissues evolved dedicated transport mechanisms involving the alpha-tocopherol tran

185 Structural investigations suggest that the transport mechanism is defined by conformational changes

186 than IAA in Arabidopsis hypocotyls, and the transport mechanism is distinct from IAA transport.

187 The charge-transport mechanism is explained by direct experimental

188 Direct pore-scale understanding of the DMP transport mechanism is important for further improvement

189 Presently, this bimodal transport mechanism is not well understood and is descri

190 The hCTR1-mediated copper transport mechanism is not well understood, nor has any

191 We propose that this proton transport mechanism is operational and serves as a funct

192 mote nuclear localization of CLKs, but their transport mechanism is presently unknown.

193 in non-neuronal tissues have shown that this transport mechanism is reversibly regulated by phosphory

194 asmic transport in eukaryotic cells, but its transport mechanism is still not understood.

195 work relates to function and gives rise to a transport mechanism is still unclear.

196 lso show that enhancement of the anterograde transport mechanism is the cause of the seizure phenotyp

197 This vapor-phase single Fe atom transport mechanism is verified by synthesizing Fe(1)(II

198 tructural basis underlying these distinctive transport mechanisms is puzzling because CLC channels an

199 The importance of such intracellular transport mechanisms is underscored by the various disor

200 ent laboratory studies of a newly recognized transport mechanism: "levitation" of saturated sediment

201 We postulate that UapA uses an elevator transport mechanism likely to be shared with other struc

202 nerated in ice-rich subsurface layers with a transport mechanism linked to solar illumination, but th

203 vation suggests that many aspects of the NPC transport mechanism may be understood based on general b

204 re that such a strain-gradient-enhanced mass transport mechanism may prove essential for understandin

205 Similar transport mechanisms may apply to a wide variety of rela

206 reveal the relative importance of different transport mechanisms, movement of GFP-labeled RNP partic

207 s suggests that a so far elusive, more basic transport mechanism must have existed and may still be t

208 ptake suggests that pericytes have molecular transport mechanisms not present in other brain cells.

209 However, when d > 4 nm, a change in transport mechanism occurs which coincides with light em

210 The data support a transport mechanism of DRO to groundwater via accidental

211 of SWEETs are valuable for understanding the transport mechanism of eukaryotic SWEETs and may be usef

212 piece of information in modeling the energy transport mechanism of flares, which is an important iss

213 ing the central role of this residue for the transport mechanism of GlcP(Se) A neutral replacement of

214 However, the transport mechanism of lipid-modified Wnts through the h

215 Despite its clinical relevance, the transport mechanism of MATE proteins remains poorly unde

216 our studies reveal the substrate binding and transport mechanism of MCTs, elucidate the mode of actio

217 adly used as a model system for studying the transport mechanism of neurotransmitters because of its

218 inomycin, we have elucidated the fundamental transport mechanism of phenylthiosemicarbazones which is

219 protein revealed that the photocycle and the transport mechanism of PsChR1 differ significantly from

220 of PaNhaP offer unique new insights into the transport mechanism of sodium/proton antiporters.

221 To investigate the transport mechanism of the complex RbsABC2, we probed in

222 Here, we defined the transport mechanism of the FNT from the amoebiasis paras

223 In this study, the vacuolar transport mechanism of the main TIAs accumulated in C. r

224 Here, we use new insights into the transport mechanism of the mitochondrial ADP/ATP carrier

225 The transport mechanism of the two kidney-specific SLC34 pro

226 is work provides important insights into the transport mechanism of the ZIPs broadly involved in tran

227 s for understanding the structure and proton transport mechanism of this protein in brown adipose tis

228 o play a role in the export of zinc, but the transport mechanism of ZntB is poorly understood and bas

229 ition, physiological relevance, and electron transport mechanisms of bacterial nanowires remain uncle

230 By studying the anion binding affinity and transport mechanisms of four other anion transporters, w

231 ts within endosomes because of the endosomal transport mechanisms of many nanomedicines within cells.

232 s study places constraints on the source and transport mechanisms of methane found in groundwater wit

233 r understanding proton, sodium, and chloride transport mechanisms of microbial rhodopsins.

234 l allow a more detailed understanding of the transport mechanisms of other plastic crystal electrolyt

235 into the influence of nanostructuring on the transport mechanisms of small molecules and nucleic acid

236 ion membrane to shed light on water and salt transport mechanisms of such membranes.

237 ng of the structural basis for the different transport mechanisms of the SLC1 family.

238 al data that have provided insights into the transport mechanisms of these intricate molecular machin

239 Disruptions of the underlying transport mechanisms, often caused by mutations that alt

240 We then explore the impact of two different transport mechanisms on the vertical concentration distr

241 enging to predict the impacts of various gas transport mechanisms on well performance with arbitrary

242 occus thermophilus, at least two alternative transport mechanisms operate to move peptides into the c

243 We thus report here a unique, activationless transport mechanism, operative over 8-22-nm distances wi

244 d by a relatively low-temperature non-linear transport mechanism or a high-temperature Mott transitio

245 ly associated with particle acceleration and transport mechanisms powered exclusively by enhanced sol

246 l cells is mediated by two distinct membrane transport mechanisms: proton gradient-driven and ATP-bin

247 entified, but the molecular details of their transport mechanism remain poorly characterized.

248 in the CaCA superfamily are unknown, and the transport mechanism remains speculative.

249 the nature of the molecular cargo, and their transport mechanisms remains undetermined.

250 he Au nanoclusters is evidenced by a hopping transport mechanism reminiscent of doped, disordered org

251 The various transport mechanisms responsible for the biokinetics of

252 novel thiazide-sensitive electroneutral NaCl transport mechanism resulting from the parallel operatio

253 conductivity approaching that of metals, the transport mechanism should be discernible by modelling t

254 Different transport mechanisms, spanning from pure Brownian diffus

255 a cytosolic carrier for Ras, the functional transport mechanism still remains largely elusive.

256 ETHODS AND We demonstrate that transcellular transport mechanisms substantially contribute to lymphat

257 wever, other important aspects of the proton transport mechanism such as gating, and the ability to o

258 . subtilis encodes yet additional classes of transport mechanisms, suppressor strains that permitted

259 bration processes, including a complementary transport mechanism termed a parallel particle pathway (

260 These data provide evidence for a transport mechanism that applies to a major class of sec

261 n in the AE1(CTD), and to propose a possible transport mechanism that could explain why selected muta

262 ers function according to a non-conventional transport mechanism that defies the fundamental tenets o

263 y a pH gradient across the membrane, using a transport mechanism that does not resemble the one propo

264 served high KIE values are consistent with a transport mechanism that involves through-H-bonds of the

265 ends represents a newly uncovered chromosome transport mechanism that is independent of plus end forc

266 icle-rich water at the front, highlighting a transport mechanism that is not captured by sediment tra

267 trongly suggest the presence of an active GA transport mechanism that would represent an additional l

268 xperiments were carried out to determine the transport mechanisms that are responsible for the UV (ul

269 ddition to providing insight into the proton transport mechanism, the demonstrated approach offers a

270 azard (5% v/v) if diffusion is the only mass transport mechanism through the deeper vadose zone.

271 that PBLs activated the reverse cholesterol transport mechanism to enhance the metabolism of the oxL

272 evelopment, utilizes a "Trojan horse" active transport mechanism to enter bacteria and has proven in

273 question whether trees can rely on a passive transport mechanism to move carbohydrates from their lea

274 Cells employ regulated transport mechanisms to ensure that their plasma membran

275 ther biomarkers are found to possess evident transport mechanisms to pass the blood-brain barrier.

276 SIRT1 and AMPK also act on sodium transport mechanisms to reduce intracellular sodium conc

277 hiphilic copolymers) that exploit endogenous transport mechanisms to traverse the BBB, enabling deliv

278 which provides a second hole-generation and transporting mechanism to minimize the aforementioned de

279 suggests that defects in syntabulin-mediated transport mechanisms underlie the synaptic dysfunction a

280 omparable to viral trafficking of non-active transport mechanism upon cellular entry, active transpor

281 The apical to basal transport mechanism was studied using bradykinin as cont

282 Evidence of these transport mechanisms was seen with reduction of insulin

283 e structural framework underlying the NaAtm1 transport mechanism, we determined eight structures by X

284 bust conclusions about the Na(+)/K(+)-ATPase transport mechanism, we did not rely on ATPase activity

285 at these water wires are central to the H(+) transport mechanism, we identified I109 as the residue t

286 To provide molecular details of its transport mechanism, we present cryo-EM structures and a

287 ate how, with new insights into the chemical transport mechanisms, we can move towards a more fundame

288 volume, pseudovacancy arrays, and collective transport mechanisms; we show that the excess volume cor

289 96), Glu(198), Lys(873), and Asn(874) in the transport mechanism were elucidated.

290 nt sensor, but its substrate specificity and transport mechanism were unknown.

291 studies in which inhibitors of these active transport mechanisms were applied.

292 Three distinct transport mechanisms were observed for 4.5-22-nm-thick o

293 indings and analyses, we propose a model for transport mechanism where CmeB protomers function indepe

294 ned with functional FRET assays to propose a transport mechanism where each CmeB protomers is functio

295 our results provide insight into the proton transport mechanism, which may also improve ionic transp

296 This transport mechanism, which occurs at applied electric fi

297 after infusion, suggesting a possible active transport mechanism, which was further supported by the

298 tenuation of transmitochondrial electrogenic transport mechanisms with consequent compromised malate-

299 O1 is the primary apical IL-13-induced Cl(-) transport mechanism within the esophageal epithelium, an

300 , the results provide evidence for diverging transport mechanisms within a prokaryotic MATE subfamily