ライフサイエンスコーパス: tritiated

1 ge conversion of tritiated corticosterone to tritiated 11-dehydrocortico-sterone when corticosterone

2 detail a synthetic method that easily gives tritiated 2-AG from [5,6,8,9,11,12,14,15-(3)H(N)]arachid

3 radiolabeled endocannabinoid as needed gave tritiated 2-arachidonoylglycerol [(3)H]2-AG with a speci

4 ght into this unique enzymatic reaction, the tritiated 2-methylene-ACC was prepared and incubated wit

5 gain further insight into this inactivation, tritiated 2-methylene-ACC was prepared and used to trap

6 ssay, mitochondrial dehydrogenase assay, and tritiated [3H] thymidine incorporation, respectively.

7 properties of purified alpha v beta 3, using tritiated [3H]SK&F-107260 as the radiolabeled ligand.

8 ults in transfer of (3)H to AdoMet, while no tritiated 5'-deoxyadenosine is observed.

9 incubated sections of rat visual cortex with tritiated (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]-cyc

10 incubated sections of cat visual cortex with tritiated (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]-cyc

11 20 microCi of tritiated 8-iso-PGF2alpha was infused over 1 h into a ma

12 In the first experiment, tritiated ABA ((3)H-ABA) and gibberellic acid ((3)H-GA3)

13 Transport of label after application of tritiated abscisic acid showed no polarity and was not a

14 lga Chlamydomonas reinhardtii was studied by tritiated acetate incorporation.

15 netics can explain the functional contrasts, tritiated Ad5 E1A and HPV16 E7 peptides were injected in

16 chromatography and RPE cultures labeled with tritiated adenine or myo-inositol, respectively.

17 Tritiated adenosylcobalamin, labeled at the exchangeable

18 When 5'-tritiated AdoMet is used in the reaction with unlabeled

19 The generation of all-trans retinal from tritiated all-trans retinol was analyzed by HPLC.

20 Tritiated amino acid injections into CA1, prosubicular,

21 Tritiated amino acid injections were placed into the hip

22 clei and by mapping anterograde transport of tritiated amino acid precursors injected into the dentat

23 n e maleate (MK-801), tritiated kainate, and tritiated amino-3-hydroxy-5-methyl-isoxazole-4-propionic

24 n e-maleate (MK-801), tritiated kainate, and tritiated amino-3-hydroxy-5-methyl-isoxazole-4-propionic

25 lo[1,5-a]pyridine ((11)C-Lu AE92686) and its tritiated analog (3)H-Lu AE92686.

26 Furthermore, using a tritiated analog of the NOS inhibitor N(G)-nitro-L-argin

27 cGMP-dependent protein kinase (PKG) using a tritiated analogue to purify a approximately 120-kDa pro

28 promising radioligand, and the corresponding tritiated and (11)C-labeled compounds were synthesized.

29 technique, we perform rapid synthesis of 20 tritiated and 10 carbon-11-labelled complex pharmaceutic

30 om TLR4 and CD14 knockout C57BL/6 mice using tritiated and fluorescein-labeled LPS.

31 m of binding of the synthesized compounds, a tritiated antagonist, (R)-N(alpha)-diphenylacetyl-N(omeg

32 Tritiated arachidonic acid and phosphatidylinositol 3,5-

33 proton abstraction using a peptide with Glu tritiated at the gamma-carbon position revealed that poo

34 initial DHAP concentration using DHAP highly tritiated at the pro-R position.

35 Equilibrium binding studies utilizing a tritiated ATP-competitive inhibitor were also consistent

36 bstitution for F1764 (mutant F1764A) reduces tritiated BTX-A-20-alpha-benzoate binding affinity, caus

37 tation of caveolin-1 from cells labeled with tritiated cholesterol or the photoactivable cholesterol

38 greater sensitivity and resolution than the tritiated compound.

39 ovalent attachment of the biotin moiety to a tritiated compound.

40 The direct comparison of uptake of tritiated compounds demonstrated more efficient system x

41 Binding of tritiated compounds to brain tissue sections of AD patie

42 mogenized rat eyes (percentage conversion of tritiated corticosterone to 11-dehydrocorticosterone; me

43 eye assessed as the percentage conversion of tritiated corticosterone to tritiated 11-dehydrocortico-

44 d by a standard receptor binding assay using tritiated CP-55,940 as the radioligand and compared to a

45 Bidirectional transport of tritiated CSA, verapamil, and dexamethasone (0.5 or 5.0

46 ssessed by quantitative autoradiography with tritiated cyanoimipramine ([(3)H]CN-IMI), was decreased

47 the SSRI sertraline were investigated using tritiated cyanoimipramine to measure SERT binding sites.

48 The tracers employed were tritiated cyclic nucleotides and a series of oligomaltos

49 LSK274, tritiated His262; 176NGGTLYTCALR186, tritiated Cys183; and 353TVEWVGSLVDR363, tritiated Trp35

50 Binding of tritiated cytisine and nicotine to cell homogenates reve

51 F-FDG signal, we have measured the uptake of tritiated deoxyglucose (DG) in neutrophils isolated from

52 eled ligands, and we therefore synthesized a tritiated derivative of (2S,3S)-3-{3-[4-ethylbenzoylamin

53 The P-gp substrate, tritiated digoxin ([(3)H] digoxin), was co-administered

54 et, acylpeptide hydrolase, was isolated as a tritiated-diisopropylfluorophosphate-reactive protein fr

55 n was also deduced by specific labeling with tritiated-diisopropylfluorophosphate.

56 kappa sensitization, the present study used tritiated dopamine release assays to examine the inducti

57 No changes were seen in release of tritiated dopamine, in response to applied KCl or amphet

58 heir effect on human MRP1-mediated uptake of tritiated estradiol glucuronide into inside-out membrane

59 valuate the intracellular phosphorylation of tritiated F-18 FDG in human lung cancer and breast cance

60 The biodistribution of tritiated-FK506 administered i.v. showed that the drug r

61 mparison of both assay types, we synthesized tritiated fluorescent neurotensin receptor ligands ([(3)

62 discovery of both PF-04725379 (11), which in tritiated form became a novel ligand for characterizing

63 cally relevant as possible, we synthesized a tritiated form of the specific P. aeruginosa glycolipid

64 A tritiated form of volicitin was synthesized and shown to

65 Brain sections were labeled with the tritiated forms of mu-, delta- and kappa-opioid ligands;

66 Tritiated forms of polyglutamyl folates are not commerci

67 During intravenous glucose tolerance tests, tritiated glucose (1.2 microCi/kg) was injected with col

68 Tritiated glucose infusion was used to measure rates of

69 A 3-tritiated glucose was used to determine glucose kinetics

70 in euglycemic cycling exercise at 50% VO2max Tritiated glucose was used to measure glucose kinetics.

71 Glucose kinetics were determined by three-tritiated glucose, and muscle sympathetic nerve activity

72 rinsulinemic clamp combined with infusion of tritiated glucose.

73 Glucose kinetics was determined by 3-tritiated glucose.

74 rats, glucose kinetics was determined using tritiated glucose.

75 tic peptide (135EIIQNGHEEEPLENTWPAPYPHSK159, tritiated His142).

76 ic peptides: 251GQFYYISDDTPHQSYDNLNYTLSK274, tritiated His262; 176NGGTLYTCALR186, tritiated Cys183; a

77 ed by NaB(3)H(4) reduction and the resulting tritiated hydroxy fatty acid then is tosylated, separate

78 viously described using azido-Q that was not tritiated (i.e., not radiolabeled).

79 olar auxin transport was measured by tracing tritiated IAA in excised shoots.

80 However, ATP can compete with the tritiated inhibitor for binding to only the active form

81 Upon combining the tritiated inhibitor with [2-14C]-thiamin diphosphate, no

82 le 1 was also effective in stimulating basal tritiated inositol monophosphate production in the neona

83 NC7437) decreased cellular proliferation and tritiated inositol phosphate levels in metabolically lab

84 Yeast cells are incubated with tritiated inositol, which is taken up and metabolized in

85 ole level by reaction of dithiothreitol with tritiated iodoacetic acid (I-C[3H(2)].CO(2)H).

86 pled to isothermal titration calorimetry and tritiated IP(6) binding assays confirmed two-site bindin

87 An improved microscale synthesis of 2-tritiated isopropanol ([2-3H]iPrOH) and R-tritiated redu

88 ,d]-cyclohepten-5,10imin e maleate (MK-801), tritiated kainate, and tritiated amino-3-hydroxy-5-methy

89 ,d]-cyclohepten-5,10imin e-maleate (MK-801), tritiated kainate, and tritiated amino-3-hydroxy-5-methy

90 DL forms of the dipeptide Leu-Leu inhibited tritiated L-carnosine uptake by approximately 60%, 40%,

91 uated by computer modeling and inhibition of tritiated L-carnosine uptake.

92 Uptake of tritiated L-carnosine was monitored using conjunctival e

93 uman placental villi incubated in vitro with tritiated leucine ([3H]leu).

94 eradish peroxidase, and autoradiography with tritiated leucine and/or proline.

95 Three tracers were utilized: tritiated leucine, biotinylated dextran amine, and wheat

96 esicles from mice lacking SV2A do not bind a tritiated LEV derivative, indicating that SV2A is necess

97 Tritiated ligands used to measure binding site density w

98 (4 h+) showed a substantial concentration of tritiated macromolecules in the Golgi complex and in the

99 e autoradiographic evidence for secretion of tritiated macromolecules.

100 ubunit, we labeled rod outer segments with a tritiated methyl donor.

101 3T3-L1 adipocytes increased incorporation of tritiated mevalonic acid in p21(ras) in a dose-dependent

102 Tritiated misonidazole (3H-MISO) is a marker which prefe

103 ptor of interest are labeled by feeding with tritiated myo-inositol.

104 Both lactam analogues competed with tritiated [Nle12]-alpha-factor for binding to the alpha-

105 ssues were then removed and analyzed for the tritiated NNK and its metabolites.

106 One hundred ng of tritiated NNK were instilled in the distal trachea of th

107 ce quenching and saturation equilibrium with tritiated ouabain, Ab 1-10 exhibited 200 nM affinity for

108 THA EF with fractional water production from tritiated palmitate further confirms a correlation of th

109 idation rates were determined by infusion of tritiated palmitate into the left anterior descending ar

110 n rates, determined by water production from tritiated palmitate.

111 Maximal number of platelet tritiated paroxetine binding sites (Bmax) and dissociati

112 The Bmax, but not Kd, values of platelet tritiated paroxetine binding was inversely correlated wi

113 ing isolated bovine neutrophils labeled with tritiated phospholipid substrates of the two enzymes.

114 Tritiated photoaffinity analogs of the natural lepidopte

115 in a 113 +/- 11% increase in the amounts of tritiated platelet-activating factor ((3)H-PAF) released

116 c acid at 0 degree C, significant amounts of tritiated polyuridylic acid are converted to acid-solubl

117 lability and permit quantitative recovery of tritiated polyuridylic acid by trichloroacetic acid prec

118 ic acid precipitation is used to recover the tritiated polyuridylic acid present in a hybrid with pol

119 ctivity can occur because of the lability of tritiated polyuridylic acid.

120 toanesthesia." Coupling this behavior with a tritiated probe, we performed unbiased, time-resolved ge

121 P81 after intravitreous injections of either tritiated proline or wheat germ agglutinin-horseradish p

122 Tritiated proline was injected into the right eye 1 d af

123 Second, intravitreal injections of tritiated proline were used to identify hypothalamic ret

124 ed with tritiated sodium borohydride and the tritiated proteins were separated on SDS-PAGE.

125 We have found that a tritiated pyridinylimidazole, SB202190, has an equal aff

126 n proximity assay technology: binding of the tritiated radioligand to the commercially available stre

127 d for their ability to compete against three tritiated radioligands at their distinct binding sites i

128 2-tritiated isopropanol ([2-3H]iPrOH) and R-tritiated reduced beta-nicotinamide adenine dinucleotide

129 ed specific and saturable nuclear binding of tritiated RU1881 and that alpha-DHT stimulated the activ

130 ations were functionally characterized using tritiated ryanodine binding and single-channel recording

131 dded to methylate the resulting peptide with tritiated S-(5'-adenosyl)-l-methionine.

132 nd to frog Rh* and P-Rh* and to compete with tritiated SalArr1 for amphibian P-Rh* was compared.

133 Complexes of tritiated SH2 fusion protein and biotinyl-phosphopeptide

134 atelets modified by WR-K and then reduced by tritiated sodium borohydride (NaB[3H]4) showed the prese

135 Protein carbonyls were derivatized with tritiated sodium borohydride and the tritiated proteins

136 e chromatography, we were able to detect one tritiated species which co-migrated with an omega-NG-mon

137 e chromatography, we were able to detect two tritiated species.

138 xogenously added radiolabeled ATP instead of tritiated sphingosine.

139 xpressing either D2 or D3 receptors by using tritiated spiperone as radioligand for competition studi

140 lls expressing either D2 or D3 receptor with tritiated spiperone to evaluate inhibition constants (K(

141 ls expressing either D2 or D3 receptors with tritiated spiperone to evaluate inhibition constants (K(

142 ls expressing either D2 or D3 receptors with tritiated spiperone to evaluate inhibition constants (Ki

143 constant and enthalpy of activation for the tritiated substrate from competitive KIE experiments.

144 of tritiated water after the addition of the tritiated substrate was detected and used to measure DES

145 percentage of SNB motoneurons to accumulate tritiated testosterone or its metabolites.

146 xogenous KL to the MLR led to an increase in tritiated thymidine (3[H]-TdR) incorporation in the abse

147 njected intraperitoneally (twice daily) with tritiated thymidine (3H-TdR), beginning at 17 days of ge

148 ed to the radioactive DNA replication marker tritiated thymidine ([(3)H]dT, or TdR) at early embryoni

149 CHO cells were labeled with tritiated thymidine ([3H]dTTP) for 12 hours and subseque

150 ion was determined by labeling cultures with tritiated thymidine ([3H]TdR) and scoring its incorporat

151 1.6 [95% CI 0.5-5.1]) or change in uptake of tritiated thymidine (counts per minute) (OR 0.7 [95% CI

152 This was confirmed by injecting tritiated thymidine 24 hr after the BrdU and seeing no d

153 Tritiated thymidine and autoradiographic techniques and

154 Tritiated thymidine and autoradiographic techniques were

155 d cytokine production were measured by using tritiated thymidine and Luminex MagPix, respectively.

156 cells induced to enter S were measured with tritiated thymidine and radioautography.

157 with peptides of streptococcal M5 protein in tritiated thymidine assays.

158 Tritiated thymidine autoradiography and bromodeoxyuridin

159 By using tritiated thymidine autoradiography, we observed that th

160 Tritiated thymidine based lymphocyte proliferation assay

161 rough successive divisions; DNA labeled with tritiated thymidine in infancy is still present in the s

162 iameter or the number of cells incorporating tritiated thymidine in the lesion.

163 Tritiated thymidine incorporation analyses revealed sust

164 .3- and 1.6-fold increases, respectively, in tritiated thymidine incorporation and bromodeoxyuridine

165 and peripheral blood were measured by using tritiated thymidine incorporation and carboxyfluorescein

166 ed the HEP G2 doubling time in culture using tritiated thymidine incorporation and direct cell counts

167 ctionality of fetal cells was also restored; tritiated thymidine incorporation and insulin content an

168 Cell division rates were determined by tritiated thymidine incorporation and Ki67 immunoreactiv

169 and on cell proliferation, as determined by tritiated thymidine incorporation and proliferating cell

170 Tritiated thymidine incorporation assay revealed that Cu

171 With tritiated thymidine incorporation assays, we found that

172 s on CTLL-2 proliferation were determined by tritiated thymidine incorporation immediately or 24 h af

173 of RR was monitored, indirectly by measuring tritiated thymidine incorporation into DNA and directly

174 s and 1.5-fold in Ba/ F3 cells and decreased tritiated thymidine incorporation into DNA corresponding

175 Tritiated thymidine incorporation studies revealed cardi

176 or -15, cell proliferation was determined by tritiated thymidine incorporation, and IL-2 and -15 rece

177 The method involves an initial injection of tritiated thymidine into chick embryos, followed a speci

178 Incorporation of tritiated thymidine into whole brain DNA demonstrated th

179 neurogenesis was initially studied with the tritiated thymidine technique, later replaced by the inj

180 Analysis of tritiated thymidine uptake by the tibia and fibula demon

181 Proliferation was studied by using tritiated thymidine uptake with or without MSCs.

182 d immunosorbent assay, cell proliferation by tritiated thymidine uptake, and cell surface molecule ex

183 Tritiated thymidine was given 1 h before death.

184 ession of p21WAF-1/CIP1 and incorporation of tritiated thymidine were found to be mutually exclusive.

185 ll sorter analysis, continuous labeling with tritiated thymidine, and time-lapse videomicroscopy docu

186 Cultures were pulsed with tritiated thymidine, harvested, and radio label incorpor

187 Uptake of tritiated thymidine, L-leucine, L-methionine and FDG int

188 ability of pretreated leaves to incorporate tritiated thymidine, uridine, and leucine into macromole

189 TGF-beta1, as determined by incorporation of tritiated thymidine, whereas those from 5 patients were

190 e cell cycle by intraperitoneal injection of tritiated thymidine.

191 s assessed by measuring the incorporation of tritiated thymidine.

192 an unperturbed culture with a short pulse of tritiated thymidine.

193 Cell turnover, assessed by tritiated-thymidine (thymidine) autoradiography, increas

194 Tritiated-thymidine autoradiographic techniques and 5-br

195 The following five classes of tritiated-thymidine labeled cells were identified in the

196 The cell proliferation marker tritiated-thymidine was infused, with or without TGFalph

197 Two new tritiated tracers for angiotensin and neurotensin recept

198 86, tritiated Cys183; and 353TVEWVGSLVDR363, tritiated Trp356.

199 7-Tritiated valiolamine (8), valienamine (2), and validami

200 n S1, in which the side chain of Ser-180 was tritiated, was photocleaved tritium was released from th

201 pidermal water loss and skin permeability to tritiated water (3H2O) and the lipophilic penetrant sulf

202 Typically, (3)H is present as tritiated water (HTO) and can become adsorbed into struc

203 amounts of liquid tritium are discharged as tritiated water (HTO) by the nuclear industry into the E

204 Tritiated water (HTO), a ubiquitous byproduct of the nuc

205 st 1 order of magnitude higher than that for tritiated water (HTO), although a similar behavior could

206 g rat liver microsomes, and the formation of tritiated water after the addition of the tritiated subs

207 interpret recent laboratory measurements of tritiated water and Cs diffusivity in Callovo-Oxfordian

208 as confirmed by determining incorporation of tritiated water into fatty acids.

209 Aromatase activity, assayed by the tritiated water method, was stimulated in both frontal s

210 linear relationship of FTHA EF to fractional tritiated water production was found.

211 incorporated following prolonged exposure to tritiated water vapor (HTO) or tritium/hydrogen gas (HT)

212 ruled out by the results of experiments with tritiated water.

213 lic (probably hydroxylated) derivatives plus tritiated water.

214 aborious vacuum distillation of the released tritiated water.

215 de bond between two ligands, one of which is tritiated whereas the other is biotin-tagged.

216 rably higher compared to previously reported tritiated Y(4)R ligands.