ライフサイエンスコーパス: tumor cell line

1 ioxidant potential and cytotoxic activity in tumor cell lines).

2 rectal cancer patients and from a metastatic tumor cell line.

3 mals by subcutaneous implantation of a human tumor cell line.

4 on and apoptosis induction in a human breast tumor cell line.

5 candidate microRNA biomarkers in a rat solid tumor cell line.

6 bserved experimentally in 11 patient-derived tumor cell lines.

7 ey have improved cytotoxic functions against tumor cell lines.

8 ted potent antitumor activity against breast tumor cell lines.

9 complex with cytotoxic activity against some tumor cell lines.

10 ity (>10 muM) when evaluated against several tumor cell lines.

11 s determined in human pancreatic tissues and tumor cell lines.

12 ts involving bevacizumab and three different tumor cell lines.

13 CI panel of 60 human hematological and solid tumor cell lines.

14 cytostatic activity in a range of different tumor cell lines.

15 reast and skin) as well as on the surface of tumor cell lines.

16 enesis and development of drug resistance in tumor cell lines.

17 ected by Western blot analysis of a group of tumor cell lines.

18 rties and replication kinetics on a panel of tumor cell lines.

19 tion of their selectivity against a range of tumor cell lines.

20 umors from patients are preferable to clonal tumor cell lines.

21 he expression of beta-Pix in both HUVECs and tumor cell lines.

22 ased production of PGE(2) and/or IL-6 by the tumor cell lines.

23 ive activity against a large number of human tumor cell lines.

24 antitumor activity against a panel of solid tumor cell lines.

25 -transduced cells against leukemia and solid tumor cell lines.

26 eir activity at supraphysiological levels in tumor cell lines.

27 s as well as in human and mouse corticotroph tumor cell lines.

28 ation in both Xenopus egg extracts and human tumor cell lines.

29 ive activity was evaluated against two human tumor cell lines.

30 monitor K-Ras inhibition in a panel of human tumor cell lines.

31 wing low nanomolar cytotoxicity toward human tumor cell lines.

32 in several murine and human lymphoid-derived tumor cell lines.

33 erapeutic strategy by using a panel of Wilms tumor cell lines.

34 horylation and activation of SIAH2 in breast tumor cell lines.

35 egulated under conditions of hypoxia in many tumor cell lines.

36 disease progression using EGFR-mutant human tumor cell lines.

37 totoxic efficacy of C7H2 in a panel of human tumor cell lines.

38 s of 55 primary BLC cases and 17 BLC-derived tumor cell lines.

39 ivating protein showing high selectivity for tumor cell lines.

40 nt for alkylation damage resistance in these tumor cell lines.

41 frequently reduced in pancreatic tumors and tumor cell lines.

42 ding proteinbeta (C/EBPbeta) in a variety of tumor cell lines.

43 sion and evaluated their relationships using tumor cell lines.

44 of their cytotoxicity against several human tumor cell lines.

45 o recognize cancer-associated Tn epitopes on tumor cell lines.

46 ontributing to the protection of a subset of tumor cell lines.

47 ease in sensitivity to ubidecarenone vs. non-tumor cell lines.

48 f USP27X decreased Snail1 protein in several tumor cell lines.

49 ((223)Ra) using 28 genetically diverse human tumor cell lines.

50 assessed their cytotoxicity in various human tumor cell lines.

51 glioblastoma and atypical teratoid rhabdoid tumor cell lines.

52 ular uptake of 4-7-[(18)F]FTrps in different tumor cell lines.

53 on of pMEK and proliferation) in KRAS mutant tumor cell lines.

54 vitro against Hek293, Jurkat, K562, and A549 tumor cell lines.

55 growth inhibition of both leukemia and solid tumor cell lines.

56 es and CA in patient tumors, xenografts, and tumor cell lines.

57 yrimidines with potent activity against TNBC tumor cell lines.

58 EMP2 expression in both patient samples and tumor cell lines.

59 of 1-3 muM against proliferation of several tumor cell lines.

60 in SS tumor cells with those in >130 non-SS tumor cell lines.

61 heir high cytotoxicity toward LNCaP and PC-3 tumor cell lines.

62 ms and efficiencies of killing of a range of tumor cell lines.

63 ZEB1 fostered micronuclei formation in TNBC tumor cell lines.

64 ntrol patients as well as 12 UM and 64 other tumor cell lines.

65 cells from doxorubicin-resistant metastatic tumors (cell line 4T1-R).

66 We used a human mammary tumor cell line (4T1) treated by an antitumor compound,

67 and (18)F-(2S,4R)4F-GLU was determined in 3 tumor cell lines (9L, SF188, and PC-3) at selected time

68 demonstrated with inhibitors 9 and 14 in two tumor cell lines (A549, D54).

69 n28 can reprogram the Ewing's sarcoma family tumor cell line A673 to produce stem cell-like colonies

70 In human tumor cell lines, ABCC4 knockdown and inhibition reduced

71 In a MCL-1 dependent human tumor cell line, administration of compound 30b rapidly

72 erative activities against a panel of tested tumor cell lines along with a better safety ratio of app

73 Tumor growth varies by tumor cell line and mouse strain used.

74 y (GI50 10-66.9 nM) against the NCI 60 human tumor cell line and significant potency against tubulin

75 recurrently expressed in a number of breast tumor cell lines and a clinical tumor sample.

76 ed efficiency in inhibiting proliferation in tumor cell lines and a rat xenograft model.

77 s display cytotoxic activity against several tumor cell lines and activated, but not resting, immune

78 ion is down-regulated in grade IV astrocytic tumor cell lines and also in clinical cases of the disea

79 ed from mouse tissues and primary pancreatic tumor cell lines and analyzed by reverse-transcription p

80 ioxidant activities and cytotoxicity against tumor cell lines and antimicrobial effects were also obs

81 ds have anticancer activity in several solid tumor cell lines and are less toxic in a normal human lu

82 usters from the database of the NCI-60 human tumor cell lines and associated each cluster with functi

83 were activated by and destroyed ErbB(+) EOC tumor cell lines and autologous tumor cultures.

84 We found that a subset of brain tumor cell lines and BTICs expressed high constitutive l

85 treatment increased PD-L1 expression in the tumor cell lines and caused up to a 12-fold increase in

86 spectrum of ligand expression by both human tumor cell lines and certain human primary cells.

87 have been hampered by poorly-differentiated tumor cell lines and genetically-intractable primary cel

88 Here we screened 12 human tumor cell lines and identified 3 that are growth inhibi

89 COPZ1) was down-regulated in the majority of tumor cell lines and in clinical samples of different ca

90 Some have subpicomolar IC50 values in human tumor cell lines and in primary chronic lymphocytic leuk

91 duces cell death in a variety of Ras-mutated tumor cell lines and increases survival in an in vivo mo

92 ed in primary human neuroblastoma tumors and tumor cell lines and is necessary for their in vitro and

93 ession of MGL suppressed colony formation in tumor cell lines and knockdown of MGL resulted in increa

94 s, with 5- and 8-residue fragments formed in tumor cell lines and only the 8-residue fragment formed

95 Using both tumor cell lines and patient samples, we show that tumor

96 essed by flow cytometry and qRT-PCR in brain tumor cell lines and patient tumor-derived brain tumor-i

97 tion with the levels of MET protein in human tumor cell lines and patient-derived tumor materials.

98 increases CD20 levels in established B-cell tumor cell lines and primary malignant cells.

99 fic in vitro and ex vivo cytotoxicity toward tumor cell lines and primary tumor cells in the presence

100 stimulation and recognition of CD70-positive tumor cell lines and primary tumor cells, as shown by IF

101 Notably, the number of ALDH(hi) cells in tumor cell lines and primary tumors inversely correlated

102 ) is aberrantly overexpressed in human colon tumor cell lines and selectively required for their surv

103 cytolytic killing assays against a range of tumor cell lines and subsequent peptide epitope mapping

104 ll-autonomous apoptotic growth inhibition of tumor cell lines and that growth inhibition is associate

105 on the gene expression profiles of 60 human tumor cell lines and the in vitro sensitivities of the c

106 igh in four MMTV-Hoxb7/Her2 transgenic mouse tumor cell lines and two breast cancer cell lines transf

107 ost human cell models of cancer are based on tumor cell lines and xenografts of primary tumor cells t

108 inase-3beta inhibition in several epithelial tumor cell lines, and by Snail1 overexpression in colore

109 from several different chromosomes in seven tumor cell lines, and characterized an unprecedented num

110 tic leukemia and other Notch-dependent human tumor cell lines, and concomitantly induces cell cycle a

111 lity was observed in several mouse and human tumor cell lines, and knockdown of ATF4 significantly in

112 CXCL4L1 is also expressed in patient tumors, tumor cell lines, and murine xenografts, prompting a mor

113 ldehyde is highly cytotoxic to dox-resistant tumor cell lines, and that this benefit is absent in com

114 semination of various mammary and nonmammary tumor cell lines, and this prometastatic behavior is ass

115 92 uptake reflected PD-L1 membrane levels in tumor cell lines, and tumor tracer uptake in mice was as

116 ested by the National Cancer Institute Human Tumor Cell Line Anti-Cancer Drug Screen, and the NCI COM

117 Lastly, on the basis of the NCI human tumor cell line anticancer drug screen and the NCI COMPA

118 gands were characterized with the pancreatic tumor cell line AR42J in vitro, including assessment of

119 However, not all tumor cell lines are sensitive to statins, and clinical

120 .c.) implantation of a luciferase-expressing tumor cell line as a reporter.

121 inhibitory activity in a panel of different tumor cell lines as determined by analyses of cell viabi

122 e in Notch3 expression was observed in human tumor cell lines as well as primary human breast cancer

123 itutively phosphorylated in several lymphoid tumor cell lines as well as primary leukemia and lymphom

124 n the substitution pattern as well as on the tumor cell line, as evidenced from the annexin V-FITC/PI

125 dies, we detected K-Ras4A protein in several tumor cell lines at a level equal to or greater than tha

126 Furthermore, 30 induced death in a panel of tumor cell lines at doses 5-50 times lower than an equit

127 icient antiproliferative effect on different tumor cell lines at low micromolar concentrations.

128 M060184 show antimitotic properties in human tumor cells lines at subnanomolar concentrations and dis

129 nts with the human pancreatic neuroendocrine tumor cell line BON-1 were performed at both 0 degrees C

130 vation of lytic infection occurs not only in tumor cell lines but also in freshly isolated B cells fr

131 in upregulation were not limited to lymphoid tumor cell lines but also occurred in naturally infected

132 protein synthesis and cell proliferation in tumor cell lines but not in normal fibroblasts.

133 E silencing enhanced the radiosensitivity of tumor cell lines but not normal cells.

134 Using human pancreatic tumor cell lines BxPC3 and Capan-1, which express Cx26 a

135 endently inhibited proliferation of numerous tumor cell lines by inducing the ATM cell cycle checkpoi

136 ayed for antiproliferative activity on human tumor cell lines by MTT assay, for antioxidant potential

137 s confirmed in an independent panel of human tumor cell lines carrying diverse genetic alterations.

138 otoxicity was determined in a panel of human tumor cell lines (CH1, SW480 and A549) by means of the M

139 e show that PDE10 is elevated in human colon tumor cell lines compared with normal colonocytes, as we

140 lantation model of an Erbb2-positive mammary tumor cell line confirmed the effect of Bcl3 in malignan

141 Here, we show that subpopulations of tumor cell lines constitutively expressing high levels o

142 A tumor cell line containing mutant p53 also revealed mass

143 Heterozygous deletion of NMNAT1 in lung tumor cell lines correlates with low expression level an

144 pro-proliferative role in an immortalized MB tumor cell line (DAOY).

145 In this study, we used a tumor cell line derived from a genetically engineered mo

146 145 and PC3 prostate cancer cells and a skin tumor cell line derived from EphA1/A2 knockout mice.

147 adenocarcinomas and was highly expressed in tumor cell lines derived from mice that develop metastat

148 r Institute (Bethesda, MD) on about 60 human tumor cell lines derived from nine cancer cell types.

149 Mechanistic investigations in mammary tumor cell lines derived from wild-type or Trask-deficie

150 c manner a majority of HLA-A*0101 allogeneic tumor cell lines derived not only from PDAC, but also bl

151 ed with guinea pig brain and human RPMI 8226 tumor cell lines differed slightly but showed the same t

152 The tumor cell lines displayed degradation rates statistical

153 subsequent challenge with an OVA-expressing tumor cell line, E.G7.

154 In addition, we found that oral cavity tumor cell lines (eg, UMSCC1 and UMSCC47) overexpressing

155 overexpression of Zpo2 in MMTV-PyMT mammary tumor cell lines enhances lung metastasis.

156 o be the most effective toward all the human tumor cell lines evaluated (PC3, DU145, 2008, C13, and L

157 y phosphorylation of peptide substrate, each tumor cell line exhibited statistically different median

158 Tumor cell lines exhibited a marked increase in sensitiv

159 The Notch-high cells sorted from solid-tumor cell lines exhibited characteristics of cancer ste

160 rc, both within the human tumors and in lung tumor cell lines exposed to hypoxia.

161 the HT29, HCT116, PC-3, HepG2, JR8, and M14 tumor cell lines expressing high levels of B7h, whereas

162 nt cell lines and selective cytotoxicity for tumor cell lines expressing mutant BRAF(V600E) versus th

163 Primary mouse embryo fibroblasts (MEFs) or tumor cell lines expressing SirT3 short-hairpin RNA exhi

164 In a panel of human tumor cell lines expressing various KRAS isoforms, we sh

165 These findings illustrate the variability of tumor cell line expression of versican, and demonstrate

166 However, tumor cell lines fail to engage in complete senescence u

167 ever, their utility is reduced by the use of tumor cell lines for implantation.

168 ) expression in 4 different human pancreatic tumor cell lines for the purpose of producing derivative

169 Validation experiments with human tumor cell lines, fresh human tumor xenografts in mice,

170 ker for AsiDNA treatment was validated in 43 tumor cell lines from various tissues and 15 models of c

171 eptor expression and Akt activation in human tumor cell lines, GBM stem cells, and primary tumor biop

172 in the weakly metastatic mouse 4TO7 mammary tumor cell line had no effect on proliferation or morpho

173 Here, we use tumor cell lines harboring mutations in Cosmc, and there

174 In this article, we show that the RENCA tumor cell line harbors TAMAs that can drive an antitumo

175 or their antiproliferative activity on three tumor cell lines (HeLa, A2780, and A2780cisR) and on a n

176 fective photodynamic activity on a number of tumor cell lines (HeLa, SK-MEL-28, A549, MCF-7) with eff

177 Herein, a normal cell line (NIH/3T3) and a tumor cell line (HepG2) were cultured on the 4-MBA modif

178 and anti-proliferative activity on different tumor cell lines (HepG2, MDA-MB-231, MCF-7 and Caco2).

179 TRR, NDOR1, and NOS2A expression in 23 human tumor cell lines; however, only POR protein was detectab

180 i) using gene essentiality data from several tumor cell lines, (ii) showing that these identified met

181 Silencing of aPKC in invasive breast-tumor cell lines impaired the delivery of MT1-MMP from l

182 cells showed enhanced cytotoxicity against a tumor cell line in vitro.

183 lines are the most frequently studied human tumor cell lines in cancer research.

184 highlight the limited utility of established tumor cell lines in recapitulating the heterogeneity of

185 CCT241533 blocked CHK2 activity in human tumor cell lines in response to DNA damage, as shown by

186 nity and inhibited growth of Mcl-1-dependent tumor cell lines in the nanomolar range.

187 Investigations using multiple tumor cell lines in the orthotopic model suggested the i

188 The culture of tumor cell lines in three-dimensional scaffolds is consi

189 o inhibit cell growth of EGFR-overexpressing tumor cell lines in vitro and in a xenograft model in vi

190 eric mAb recognized several polySia-positive tumor cell lines in vitro and induced rapid endocytosis

191 s(G12V)-expressing IMR90E1A and KRAS-mutated tumor cell lines in vitro.

192 nockdown of miR-155 attenuates the growth of tumor cell lines in vivo.

193 hibits the proliferation of a panel of human tumor cell lines including Colo205 (Rb(+)) and U937 (FLT

194 ino)prop-2-e n-1-one (10ae) was tested in 20 tumor cell lines including multidrug resistant phenotype

195 to selectively kill cancer cells within many tumor cell lines including neuroblastoma or glioblastoma

196 tent and selective cytotoxicity toward solid tumor cell lines including pancreatic cancer (PANC-1) wi

197 nificant cell death in a wide range of human tumor cell lines, including glioblastoma, astrocytoma, n

198 anoma line SK-MEL-2 (IC50 = 39 nM) and other tumor cell lines, including JeKo-1 (IC50 = 22 nM), HeLa

199 oto-activation, VP may still inhibit certain tumor cell lines, including ovarian cancer, hepatocarcin

200 Moreover, overexpression of Egrs in tumor cell lines induced CEBPB and inhibited proliferati

201 Transduction of CX3CL1 and CX3CR1 in CRC tumor cell lines induced cell aggregation that strongly

202 low copy number of the ASncmtRNAs in several tumor cell lines induces cell death by apoptosis without

203 s study, we show that conditioned media from tumor cell lines induces expression of both CLIC4 and th

204 ration, whereas reexpression in a metastatic tumor cell line inhibited migration, proliferation, and

205 e direct role of oncogenic miRNAs in situ in tumor cell lines is valuable in delineating distinct det

206 Primary tumor cell lines lacking Atm expression also demonstrate

207 We also show that translocase depletion in tumor cell lines leads to the accumulation of RAD51 on c

208 cutaneous xenografts, derived from the human tumor cell lines LNCaP (prostate), A549 (lung), and U251

209 display a range of activities against human tumor cell lines, malarial parasites, and bacterial path

210 ssociated lncRNAs were studied in two breast tumor cell lines, MCF-7 and MDA-MB-231.

211 intravasation sites), and a malignant breast tumor cell line, MDA-MB-231, embedded in type I collagen

212 In a wide array of tumor cell lines, mean inhibitory concentrations (IC(50)

213 (MEFs) expressing activated Ras(V12) and in tumor cell lines MIN6 and NG108-15.

214 Simvastatin inhibited the growth of most tumor cell lines more effectively than pravastatin in a

215 or their potency to induce cell death in two tumor cell lines, mouse breast cancer cell line EMT-6 an

216 ear signaling complexes (PSC) are present in tumor cell lines, mouse lung tumors, and mouse embryonic

217 FR-iRGD also exhibited antitumor activity in tumor cell lines, multicellular spheroids, and mice.

218 utilization of a novel human LNCaP prostate tumor cell line, N-AR, which stably expresses wild-type

219 ainst a panel of 60 well-characterized human tumor cell lines (NCI-60) to uncover combinations with g

220 in and mRNA levels were decreased in ovarian tumor cell lines not expressing the protein p53.

221 After subcutaneous injection of tumor cell lines of different origin, such as NCI-H460,

222 The cytotoxic activities on a panel of human tumor cell lines of these novel oxazaphosphorines, in bu

223 ensitive to anti-PlGF, but not in refractory tumor cell lines or in endothelial cells.

224 The NCI-60 human tumor cell line panel is an invaluable resource for canc

225 tions when tested against the full NCI human tumor cell line panel.

226 pharmacological inhibition of ERAP1 on human tumor cell lines perturbs their ability to engage severa

227 Mechanistic analyses revealed that each tumor cell line presented AH1, a common endogenous retro

228 ils showed cytotoxic effects on tested human tumor cell lines, related to the furanosesquiterpenoid c

229 Blocking miR-BART-18 function in an EBV(+) tumor cell line renders cells more susceptible to IFN-me

230 Here, we report that melanoma tumor cell lines require wild-type SOX10 expression for

231 Forced expression of ERG in prostate tumor cell lines resulted in significantly increased sec

232 V) could establish persistent infection in a tumor cell line, resulting in a steady antiviral state r

233 Screens of the NCI-60 human tumor cell lines reveal that arsenoplatin-1 (AP-1), [Pt(

234 Analysis of diverse tumor cell lines revealed high ligand expression on seve

235 Further in vitro screen in 328 tumor cell lines revealed that tumor cells with KRAS, NR

236 nhibitory activity is seen in multiple human tumor cell lines, RI-1 holds promise as an oncologic dru

237 ad compound identified from the NCI-60 human tumor cell lines screen, NSC319726 (ZMC1), belongs to th

238 EGFR-1 signaling and biological responses in tumor cell lines sensitive to anti-PlGF, but not in refr

239 te with Pumilio to target E2F3, and multiple tumor cell lines shorten the 3' end of the E2F3 mRNA, re

240 nalysis of the gene expression signatures of tumor cell lines showed an inverse correlation between m

241 vitro inhibitory activity against ten human tumor cell lines showed that hydrolyzed rutin exerted a

242 Analysis of breast tumor cell lines showed that REST directly represses IRS

243 ative activity of the title compound on five tumor cell lines shows preference for the colon-rectal t

244 cytotoxic activity against a panel of human tumor cell lines similar to that of paclitaxel.

245 , in analyses of mice implanted with various tumor cell lines, soluble IL-15/IL-15Ralpha complexes (s

246 and moreover, revealed chemotherapeutic and tumor cell line specific activity patterns.

247 implanted with passaged, SHR-derived, breast tumor cell line, SST-2.

248 All tumor cell lines studied were equally susceptible to C7H

249 ionizing radiation promoted autophagy in all tumor cell lines studied, pharmacological inhibition of

250 tumor growth upon rechallenge with the same tumor cell line, suggesting the potential establishment

251 es with AZA sensitivity in the NCI-60 set of tumor cell lines, suggesting that the level of OAS1 can

252 Another gemcitabine-resistant tumor cell line, TC-1-GR, was developed in our laborator

253 ILT3.Fc inhibited the growth of CD166(+) tumor cell lines (TCL) derived from lymphoid malignancie

254 he parental virus following infection in two tumor cell lines tested, HT1080 and HeLa, and remained a

255 We identified ovarian tumor cell lines that retain UBB in a repressed state, u

256 an in vitro antitumor assay with seven human tumor cell lines, the bicyclic compounds inhibited selec

257 In some human tumor cell lines, the enhanced phosphorylation of Stat3

258 We then employed a commonly used human brain tumor cell line to screen Food and Drug Administration (

259 ncer cells trained on the responses of 1,235 tumor cell lines to 684 drugs.

260 Exposure of OV-susceptible tumor cell lines to conditioned media from RAW264.7 or p

261 spo(-/-)) mice, primary cells, and different tumor cell lines to examine the role of TSPO in erythrop

262 hibits the adhesion of polymorphonuclear and tumor cell lines to HUVECs; thus, we suggested that ICOS

263 atin or carboplatin increased the potency of tumor cell lines to induce IL-10-producing M2 macrophage

264 bition of PI3K signaling in a broad range of tumor cell lines to provide a strategy to overcome resis

265 GAT211 did not impede paclitaxel-induced tumor cell line toxicity.

266 , and the extent of delivery varied with the tumor cell line, tumor site, and host mouse strain used.

267 nd NAD(P)H oxidation levels increased in the tumor cell lines (uncoupling effect), resulting in a Del

268 en though mice were inoculated from the same tumor cell line under carefully controlled conditions.

269 and a low-passage cultured human pancreatic tumor cell line using clonogenic and DNA damage assays.

270 nd quantify their usage in major cancers and tumor cell lines using direct RNA sequencing.

271 d messenger RNA (mRNA) expression in various tumor cell lines was downregulated upon treatment with p

272 compound with significant effects on several tumor cell lines was further modified to difluoro-dioxol

273 nt neurite outgrowth in Ewing sarcoma family tumor cell lines was mediated by Frizzled3, Dishevelled

274 tion, the in vitro proliferation of the lung tumor cell lines was not affected by either CD22 antibod

275 secting the underlying mechanism in prostate tumor cell lines we show the ERG-mediated up-regulation

276 Using an in vitro mouse thymus tumor cell line, we determined that H2(18)O provides sup

277 ell line-derived xenografts, and established tumor cell lines, we first evaluated chemotherapy-induce

278 nal Cancer Institute's NCI-60 panel of human tumor cell lines were correlated with permissivity for E

279 ctivities of compounds 2 and 3 over 60 human tumor cell lines were recorded.

280 All neural tumor cell lines were sensitive to nifurtimox, and IC50

281 rating 3- to 10-fold greater potency against tumor cell lines when compared with normal cells.

282 cell death (PCD) of CD38(+) multiple myeloma tumor cell lines when cross-linked in vitro by secondary

283 ncreased cytotoxic activity against multiple tumor cell lines when maintained at low cytokine concent

284 n the low nanomolar range against a panel of tumor cell lines, whereas cytotoxicity of the 4-N-alkylg

285 of anaphylatoxins, and CDC against distinct tumor cell lines, whereas no differences in ADCC by MNC

286 ing up to 6 orders less cytotoxic in the non-tumor cell line WI38, suggesting that key DNA sequences

287 levels of gamma-tubulin and RB1 and that in tumor cell lines with a nonfunctioning RB1, reduction of

288 Conversely, in human tumor cell lines with activating MAPK mutations, inhibit

289 rmal tissue, but is highly expressed in most tumor cell lines with an intact 9p21 locus.

290 liferation, including in GSI-resistant human tumor cell lines with chromosomal translocations and rea

291 ith (18)F-BMS-986192 were performed on human tumor cell lines with different total cellular and membr

292 nhibit selectively the growth of three human tumor cell lines with IC50 values in the low micromolar

293 We apply NINJA to create tumor cell lines with inducible neoantigen expression, w

294 rther, we show lethality in invasive primary tumor cell lines with inhibiting H(+) efflux.

295 strated potent activity over a select set of tumor cell lines with particular selectivity toward mela

296 rated that treatment of a subset of BRAF(WT) tumor cell lines with RAF small molecule inhibitors resu

297 tural cytotoxin that inhibits growth of many tumor cell lines with single-digit nanomolar potency.

298 It is particularly effective against kidney tumor cell lines, with >250-fold higher anti-tumor activ

299 r and inhibited the motility and invasion of tumor cell lines without any effect on their proliferati

300 Experiments with cultures of human tumor cell lines, xenografts of human tumors into immuno