ライフサイエンスコーパス: tumor grade

1 ical platforms for testing therapies at each tumor grade.

2 pidermal growth factor receptor 2 status and tumor grade.

3 ns and suggested a positive correlation with tumor grade.

4 types, increased patient survival, and lower tumor grade.

5 uction was significantly correlated with the tumor grade.

6 oma , and it provides insights regarding the tumor grade.

7 with PSA, PSA kinetics, and original primary tumor grade.

8 bolism may be related to an association with tumor grade.

9 s, CYP27A1 expression levels correlated with tumor grade.

10 , 1.10; 95% CI, 1.01 to 1.20; P = .026), and tumor grade.

11 ed normal tissue and increased with specific tumor grade.

12 colorectal tumor tissues increased with the tumor grade.

13 ted with younger age at diagnosis and higher tumor grade.

14 ive tumors but was inversely correlated with tumor grade.

15 al features, such as gross necrosis and high tumor grade.

16 , irrespective of hormone receptor status or tumor grade.

17 in tumor samples is correlated with advanced tumor grade.

18 ze, presence of lymphovascular invasion, and tumor grade.

19 ere elevated expression correlates with high tumor grade.

20 ma (37.6% of 117 cases) correlated with high tumor grade.

21 ed PEG3 mRNA expression that correlated with tumor grade.

22 ociation between loss of MEG3 expression and tumor grade.

23 common RCC subtype) with matched gender and tumor grade.

24 and biological pathways that correlate with tumor grade.

25 x (GGI) is a 97-gene measure of histological tumor grade.

26 he TLR4 expression intensity correlated with tumor grade.

27 dicating a positive correlation with Gleason tumor grade.

28 tion in tumor tissues, which correlated with tumor grade.

29 their abundance is positively correlated to tumor grade.

30 f the uptake curve appeared to be related to tumor grade.

31 e its expression increases coordinately with tumor grade.

32 th high c-Myc expression and a more advanced tumor grade.

33 el, with the degree of loss correlating with tumor grade.

34 , number of positive lymph nodes, and higher tumor grade.

35 ted with relapse, local invasion and a worse tumor grade.

36 er biopsies and is associated with increased tumor grade.

37 mber of CD44+/alpha2beta1hi/CD133+ cells and tumor grade.

38 es of 54 gliomas of varying histogenesis and tumor grade.

39 ation between loss of BMP-RII expression and tumor grade.

40 s investigated after adjusting for stage and tumor grade.

41 t tumor angiogenesis varies depending on the tumor grade.

42 with PSA, PSA kinetics and original primary tumor grade.

43 tumor samples are positively correlated with tumor grade.

44 ete understanding of how ICP correlates with tumor grade.

45 h end-point observation, such as survival or tumor grade.

46 meters showed a significant correlation with tumor grade.

47 are increased and positively correlate with tumor grade.

48 s inversely with survival and increases with tumor grade.

49 presses tumor cell proliferation and reduces tumor grade.

50 ith shorter disease-free survival and higher tumor grade.

51 g from 10 to 41%, depending on TN status and tumor grade.

52 neuroendocrine tumors (GI-NETs) and defines tumor grade.

53 including distant metastasis, survival, and tumor grade.

54 -)) tumor subtypes, mammographic density and tumor grade.

55 ic tissue, stratifying patients according to tumor grade.

56 ression correlates with patient survival and tumor grade.

57 eptor type 2 (HER2 subtype), tumor size, and tumor grade.

58 of MLK3 was inversely correlated with HER2+ tumor grades.

59 after age correction and were compared among tumor grades.

60 ation and tumor formation, although at lower tumor grades.

61 rade 3 breast tumors, as compared with lower tumor grades.

62 ccurate Ki-67 indices and possibly incorrect tumor grades.

63 vels and elevated ANXA2 levels in increasing tumor grades.

64 y the elective nature of surgery and earlier tumor grades.

65 es, whereas no difference was identified for tumor grading.

66 de useful information for preoperative glial tumor grading.

67 ry to perfusion MR technique in preoperative tumor grading.

68 Results Low-grade tumors (grade 0, 1, or 2) demonstrated a favorable long-

69 azard ratio, 1.22 [95% CI, 1.07-1.40]), high tumor grade (1.34 [1.16-1.55]), mucinous histological ty

70 allowed full recapitulation of the original tumor (grade 2/grade 3 serous adenocarcinoma), whereas >

71 or <1.5 mm, pT stage, pN stage, LNR >/=0.2, tumor grade 3, and lymphovascular invasion were signific

72 gression [DP], 13%) versus 33% of high-grade tumors (grade 3 or 4) (complete response, 0%; partial re

73 whether prostate weight was associated with tumor grade, advanced disease, or risk of biochemical pr

74 at an academic/research program, and higher tumor grade all predicted neoadjuvant RT administration.

75 iffer by pathological stages of diagnosis or tumor grades (all P for trend > 0.1).

76 ection, n = 8), prior chemotherapy (n = 16), tumor grade (anaplastic, n = 35), and tumor location (in

77 carcinomas was strongly associated with high tumor grade and advanced disease stage.

78 cteristics (serum prostate-specific antigen, tumor grade and clinical stage) and by treatment type (r

79 ent samples, with expression increasing with tumor grade and correlating with shorter survival times

80 or progression by relating its expression to tumor grade and demonstrating its role in the regulation

81 When clinical covariates, tumor grade and estrogen receptor H-score, were included

82 n of information on breast cancer pathology (tumor grade and estrogen receptor/progesterone receptor

83 Silibinin-fed groups had a lower tumor grade and higher incidence of prostatic intraepith

84 arcinomas strongly correlates with increased tumor grade and is associated with methylation of the HO

85 P-2 expression is positively correlated with tumor grade and is highest in metastatic tumors.

86 hat PDGFR signaling quantitatively regulates tumor grade and is required to sustain high-grade oligod

87 We thus evaluated the role of tumor grade and its association with VTE.

88 The tumor grade and Ki-67 proliferation index were obtained

89 D68(+) macrophages positively correlate with tumor grade and liver metastasis in human pancreatic neu

90 sitively correlated with cell proliferation, tumor grade and malignancy.

91 ereas perilipin 2 correlates negatively with tumor grade and may be therapeutically useful.

92 binding homeobox 1 (ZEB1) is associated with tumor grade and metastasis in lung cancer, likely due to

93 tly associated with histopathological stage, tumor grade and overall patient survival in bladder tumo

94 tagenes also have predictive value regarding tumor grade and patient outcomes.

95 echanism, as well as characteristics such as tumor grade and patient survival.

96 al imaging, residual tumor in explant >2 cm, tumor grade and perineural invasion in explant.

97 er, their direct correlation with increasing tumor grade and poor prognosis has posed a long-standing

98 shown to be highly associated with advanced tumor grade and poor prognosis.

99 association of VGF expression with advanced tumor grade and poor survival in patients with lung aden

100 the high level of Mcl-1 was related to high tumor grade and poor survival of breast cancer patients.

101 ia-1 (Mcl-1) in cancers correlates with high tumor grade and poor survival.

102 ere its expression inversely correlates with tumor grade and predicts prognosis.

103 variety of human tumors and correlates with tumor grade and prognosis.

104 ith the coexpression of MTA1 as well as with tumor grade and proliferation of primary breast tumor sa

105 associated with increased proliferation and tumor grade and reduced metastasis-free patient survival

106 n oncology, where it could be used to assess tumor grade and response to treatment.

107 nd to correlate CT perfusion parameters with tumor grade and serum markers.

108 t cancer tissues and is associated with high tumor grade and shorter patient survival time.

109 At present, tumor grade and size are the primary clinicopathological

110 dependent prognostic indicator regardless of tumor grade and size, estrogen or progesterone receptor

111 creased BTG2 expression correlates with high tumor grade and size, p53 status, blood and lymph vessel

112 The analysis was stratified by tumor grade and stage and by age and comorbidity at diag

113 kb1 expression was inversely correlated with tumor grade and stage, arguing that Lkb1 inactivation or

114 lated with more advanced tumor stage, higher tumor grade and the presence of distant metastasis in Pa

115 nces in ADCs, skewness, and kurtosis between tumor grade and the presence of lymphovascular invasion.

116 including age, human papillomavirus status, tumor grade and TP53 mutation, and N classification.

117 g adenocarcinoma is critical for determining tumor grade and treatment for patients.

118 Nuclear 4ICD inversely correlated with tumor grade and tumor mitosis.

119 n, increased proliferative indices, advanced tumor grade and undifferentiated histology.

120 carce information on the association between tumor grade and VTE is available.

121 (18)F-FDOPA uptake in brain tumors predicted tumor grade and was associated with tumor proliferative

122 laminin-411 (alpha4beta1gamma1) with higher tumor grade and with expression of cancer stem cell (CSC

123 consistently overexpressed than 67LR in all tumor grades and stages.

124 A PET might serve as a noninvasive marker of tumor grading and might provide a useful surrogate of tu

125 tween enhanced NPM1 expression and increased tumor grading and poor prognosis, whereas in contrast, A

126 NOTCH3 expression correlates positively with tumor grading and the presence of lymph node as well as

127 stability attractor strongly associated with tumor grade, and a lymphocyte-specific attractor.

128 r size, positive lymph nodes, margin status, tumor grade, and age), the relative hazard for patients

129 s by helping distinguish tumor types, assess tumor grade, and attempt to determine tumor margins.

130 ted with specific cancer subtypes, increased tumor grade, and decreased overall survival.

131 associated with increased burden, increased tumor grade, and elevated serum chromogranin A (CgA).

132 or interleukin-6 (IL-6) levels increase with tumor grade, and elevated serum IL-6 correlates with poo

133 y was reviewed to determine histologic type, tumor grade, and estrogen receptor, progesterone recepto

134 the number of positive lymph nodes, T stage, tumor grade, and ex vivo proximal margin length >3.8 cm

135 is reduced in primary PCas as a function of tumor grade, and inversely correlates with the prolifera

136 sitivity, estrogen receptor negativity, high tumor grade, and large tumor size.

137 endent variable, older age, T2 disease, high tumor grade, and local recurrence were associated with r

138 and E-cadherin, Snail, metastatic potential, tumor grade, and lymph-vascular invasion during breast c

139 rmal growth factor receptor 2 (HER2) status, tumor grade, and lymphovascular invasion are relevant; O

140 omponents (fibrous, chondroid, and osteoid), tumor grade, and marrow involvement.

141 Younger age at diagnosis, poorer tumor grade, and negative estrogen receptors (ERs) were

142 varied by tumor histology, receptor status, tumor grade, and Oncotype DX scores (all P < 0.0001).

143 ons of tumor diameter and nodal status (TN), tumor grade, and other factors with patients' outcomes d

144 lates strongly with chemotherapy resistance, tumor grade, and overall survival.

145 with increased cytogenetic complexity, high tumor grade, and poor prognosis.

146 ed with elevated levels of E2F targets, high tumor grade, and poor survival.

147 e based on HER2 status, PR status, cT stage, tumor grade, and presence of bone-only metastases.

148 50 years, female sex, being married, higher tumor grade, and presence of colon tumors.

149 ypoxia gene expression signature, increasing tumor grade, and reduced patient survival.

150 nts were associated with pathological stage, tumor grade, and survival when validated by immunohistoc

151 Prognosis was dependent on tumor grade, and the presence of bone metastasis was ass

152 ntially methylated loci (DML) increased with tumor grade, and the vast majority were due to hypomethy

153 tes) of age, sex, weight, stage, tumor type, tumor grade, and treatment.

154 anti-estrogen therapy, independently of age, tumor grade, and tumor stage.

155 Functioning and nodal status, tumor grade, and vascular invasion accurately predict su

156 , tumor diameter, lymphatic vessel invasion, tumor grading, and Lauren classification, the PRSC was t

157 1; 95% CI, 1.31 to 1.69) and those with high tumor grade (AOR, 30.76; 95% CI, 26.48 to 35.73) had sig

158 tients with HCC for transplantation based on tumor grade as determined by preoperative NCB.

159 age, Lauren histotype, lymph-node ratio, and tumor grade as independent prognostic factors in gastric

160 Given the TN status, the factors of tumor grade (available in 43,590 patients) and Ki-67 sta

161 omas of the prostate can be categorized into tumor grades based on the extent to which the cancers hi

162 Because of this tumor grade-based differential growth, the E1-deleted ad

163 The effect of age and tumor grade, both individually and together, on BOLD fun

164 d hyperpolarized alanine also increased with tumor grade but showed more overlap between the groups.

165 LAMC2 expression levels were associated with tumor grade, but inversely with nodal status.

166 s in combination with PR and HER2 status and tumor grade by using the threshold of more than 30 as a

167 , Eastern Cooperative Oncology Group status, tumor grade, chemotherapy, and radiation regimen and day

168 of survival after adjusting for patient age, tumor grade, clinical tumor stage, lymphovascular invasi

169 lates with better patient survival and lower tumor grade consistent with its tumor suppressor activit

170 Stage and tumor grade continue to appear to be valid prognostic in

171 1 primary breast cancers, we found that high tumor grade correlated significantly with elevated cytop

172 is significantly associated with increasing tumor grade, decreased levels of apoptosis, and with adv

173 Tumor grade did not influence the levels of expression o

174 whereas unaligned cell lines using original tumor grades did not.

175 n was independent of patient age at surgery, tumor grade, disease stage, and IGF-II or IGFBP-3 expres

176 d that protein overexpression was related to tumor grade, disease stage, Ki-67 expression, and a shor

177 Advanced age and tumor grade do not have a combined effect for reduction

178 l survival (OS) based on clinical T/N stage, tumor grade, ER, PR, HER2, number of metastatic sites, a

179 s negatively correlate with HCC histological tumor grade, establishing this kinase as a tumor suppres

180 r age, tumor size, number of positive nodes, tumor grade, estrogen receptor status, and human epiderm

181 age younger than 50 years at diagnosis, high tumor grade, estrogen receptor-negative status, progeste

182 enting clinicopathological features, such as tumor grade, expression status of estrogen receptor and

183 status, pathologic tumor size, node status, tumor grade, facility type and location, and volume of b

184 l, a significant drop in AFP with DS and low tumor grade, favorably influence survival in these patie

185 found between tumor iodine concentration and tumor grade for both clear cell (tau = 0.85; P < .001) a

186 .52-4.50, T4 OR 6.30, 95% CI 4.71-8.42), and tumor grade (G3 OR 5.55, 95% CI 4.78-6.45, G4 OR 5.98, 9

187 y with several parameters of poor prognosis (tumor grade, growth pattern, muscle invasion, tumor stag

188 The validity of NCB to predict final tumor grade has not been previously assessed.

189 Tumor grade helps determine which tracer should be selec

190 Tumor grade (high vs low) was compared with ultrahigh-fi

191 ecrease in nuclear Smad 3 abundance and high tumor grade, high architectural grade, larger tumor size

192 tone concentrations were associated with low tumor grade, high serum creatinine levels, and concomita

193 Poor tumor grading, high American Joint Commission on Cancer

194 tion, such as World Health Organization 2007 tumor grade, histology, and isocitrate dehydrogenase 1 R

195 correlation between metabolomic profile and tumor grade/hormone receptor status was found.

196 ired eGFR (HR = 3.32, 95% CI: 1.70-6.48) and tumor grade (HR = 1.94, 95% CI: 1.36-2.77) were independ

197 T-2 expression was inversely correlated with tumor grade, implicating its potential role in glial tum

198 th associated with worse survival and higher tumor grade in breast cancer patients in multiple patien

199 ATP11B expression was correlated with higher tumor grade in human ovarian cancer samples and with cis

200 G6PC expression also correlated with tumor grade in human primary HCCs.

201 RAP1 expression is inversely correlated with tumor grade in several cancers, these data suggest that,

202 wed a substantial increase in tumor size and tumor grade in the absence of obesity and metabolic synd

203 clinical American Joint Committee on Cancer tumor grade in the IFNalpha2b group.

204 EF5 binding increased as the tumor grade increased and was significantly associated w

205 cancer tissues and is associated with higher tumor grade, increased aggressiveness, and worse prognos

206 As tumor grade increases, we find enhanced proliferation of

207 sion in 90 ccRCC patient specimens for which tumor grade information was available.

208 Accurate diagnosis and classification of tumor grade is a critical determinant for development of

209 s to define a new cohort of patients in whom tumor grade is a very important prognostic variable.

210 High tumor grade is the most consistent factor associated wit

211 sformation of low-grade glioma into a higher tumor grade is typically associated with contrast enhanc

212 elates with poor patient survival and higher tumor grade, is consistent with its oncogenic activity.

213 ends on age, World Health Organization (WHO) tumor grade, Karnofsky performance score, cytological ty

214 After excluding patients with advanced tumor grades, laparoscopic surgery was still associated

215 riate analysis was performed controlling for tumor grade, location, surgery type, functional hormonal

216 nt with surgery or radiation therapy, higher tumor grades, lower neighborhood socioeconomic status, a

217 IR patients, no demographic, pathologic (eg, tumor grade, lymph node positivity, superior mesenteric

218 specific survival by age, sex, surgery type, tumor grade, lymph node status, and use of radiation the

219 volume and ADC can be used for prediction of tumor grade, lymphovascular invasion, and depth of myome

220 T and N stage, histologic type, tumor size, tumor grade, lymphovascular invasion, perineural invasio

221 candidates for transplantation based on NCB tumor grade may be misleading, as NCB tumor grade often

222 The tumor grade may help identify patients with cancer who a

223 that the expression of ARRDC3 decreases with tumor grade, metastases and recurrences.

224 nalysis revealed that nonfunctioning tumors, tumor grade, N1 status, and vascular invasion were all i

225 y with cytoplasmic p-CDK2 (P < 0.0001), high tumor grade, negative estrogen/progesterone receptor sta

226 s (rN) (odds ratio [OR], 5.58; P < .001) and tumor grade (NET-G2 vs NET-G1: OR, 4.87; P < .001) (firs

227 nd was associated with larger tumors, higher tumor grades, node metastasis and shorter patient surviv

228 5% CI, 0.67 to 0.68) for the model including tumor grade, number of collected metastatic lymph nodes,

229 Tumor grading, number of positive lymph nodes, a context

230 Of note, higher tumor grade of human ccRCC was correlated with a concomi

231 spondingly, FCHSD2 loss correlates to higher tumor grades of NSCLC.

232 on NCB tumor grade may be misleading, as NCB tumor grade often did not correlate with grade or presen

233 creased (18)F-FDG uptake and a more advanced tumor grade or growth in breast cancer.

234 uffer from cognitive deficits, regardless of tumor grade or location.

235 kg/m(2) (obesity; OR = 2.01; P = .014), high tumor grade (OR = 0.40; P = .018), KRAS mutation (OR = 0

236 such as patient gender, age, tumor location, tumor grade, or mismatch repair status in any cancer sta

237 reduction with respect to age, nodal status, tumor grade, or progesterone receptor status and no indi

238 introduced as a combined variable to predict tumor grade, outperforming single predictors.

239 introduced as a combined variable to predict tumor grade, outperforming single predictors.

240 There was some evidence of heterogeneity by tumor grade ( P = .02), with an increased risk for low-i

241 the eastern United States (P = .02), and low tumor grade (P < .0001) were associated with ovarian pre

242 umor-associated Cyr61 protein correlate with tumor grade (P < 0.001) and with c-Met protein expressio

243 orrelates with Gleason score (P < 0.001) and tumor grade (P < 0.001).

244 imbalance on chromosome 11 in the stroma and tumor grade (P = .0013), on chromosomes 1, 2, 5, 18, 20,

245 e 5-year EFS rates differed significantly by tumor grade (P = .0044) but not by age, location, RELA f

246 Histopathologic features of PD were high tumor grade (P = .005), high Ki-67 score (P = .002), and

247 or 1alpha (P < 0.05), tumor size (P = 0.03), tumor grade (P = 0.0001), and Chalkley vessel count (P =

248 xpression was inversely associated with high tumor grade (P = 0.0017) and obesity (body mass index >

249 association between primary tumor SUVmax and tumor grade (P = 0.30).

250 es for this factor were associated with high tumor grade (P heterogeneity = 0.02), younger age at men

251 EFS was not associated with tumor grade (P= 0.98), histologic subtype (P= 0.17), or

252 e, hormone receptor status, HER2-neu status, tumor grade, pathologic tumor size, lymphatic invasion,

253 deration of Gynecology and Obstetrics stage, tumor grade, pelvic node status, and treatment with conc

254 Rather, in patients with grade IV gliomas, tumor grade played a dominant role in reduction of SI ch

255 ion in human cancers is associated with high tumor grade, poor survival, and resistance to chemothera

256 ved in human cancers is associated with high tumor grade, poor survival, and resistance to chemothera

257 antly associated with high tumor stage, high tumor grade, positive lymph nodes and presence of distan

258 dvanced T stage, lymph node metastasis, high tumor grade, positive resection margin, perineural, and

259 Histologic tumor grade predicted survival.

260 Whereas final pathologic tumor grade predicted the presence of microscopic vascul

261 here was a marked difference with respect to tumor grade, prevalence of necrosis, initial presentatio

262 rams, and BAP1 loss was associated with high tumor grade (q = 0.0005).

263 ng American Joint Committee on Cancer stage, tumor grade, R-status, and adjuvant treatment.

264 rrelated negatively and positively with lung tumor grade, respectively.

265 miRNA expression by RT-qPCR correlated with tumor grade, size, and presence of carcinoma in situ for

266 e Cox's regression analysis, age, sex, race, tumor grade, stage at diagnosis, lymph/vascular invasion

267 redictors of tumor recurrence independent of tumor grade, stage, and preoperative prostate-specific a

268 ther significant factors included age, race, tumor grade, stage, location, and N stage.

269 Its applications include tumor grading, staging, therapeutic monitoring, and prog

270 gative group with respect to age, sex, race, tumor grade, subsites and stage, or EGFR expression by a

271 he associations between clinical phenotypes (tumor grade, survival) and cell phenotypes, such as shap

272 dels were adjusted for covariates (age, sex, tumor grade, T/N stage, tumor location, Eastern Cooperat

273 justed for age, sex, primary tumor site, and tumor grade, the SUV(max) cutoff hazard ratio was 0.50 (

274 5% CI, 1.31-2.47), regardless of tumor size, tumor grade, tumor histology or radiation history.

275 tivariable Cox regression analysis including tumor grade, tumor histology, tumor sites, stage, sex, a

276 ry of BC) and prognostic factors (TNM stage, tumor grade, tumor size, age at diagnosis, estrogen rece

277 g for major clinical characteristics such as tumor grade, tumor size, anatomic site, and patient age.

278 a new tool (RSClin) that integrates RS with tumor grade, tumor size, and age using a patient-specifi

279 endent prognostic factors were nodal status, tumor grade, tumor size, and estrogen-receptor status (P

280 st for year of diagnosis, age, race, gender, tumor grade, tumor size, TNM stage, and percent of nodes

281 indicate potential for noninvasive prostate tumor grading using quantitative (111)In-capromab pendet

282 more likely to present increased pathologic tumor grade, vascular endothelial growth factor expressi

283 es of prostate tumor significantly decreased tumor grade via antiproliferative effect, and inhibition

284 World Health Organization classification tumor grade was associated with number (P<.0005) and siz

285 When the tumor grade was excluded, rN (OR, 4.73; P = .001) and ra

286 ation between tumor iodine concentration and tumor grade was investigated.

287 t of NCB and surgical pathology to determine tumor grade was poor (kappa = 0.18, P < 0.0001).

288 Primary tumor grade was the only prognostic variable significant

289 In contrast, when tumor grading was based on the final surgical specimen,

290 6), patient age (50-60 years: 3.4; 1.8-6.7), tumor grade (well differentiated: 2.2; 1.5-3.0), surgica

291 2 to 1.51; P = .65); age, margin status, and tumor grade were associated with LR-free survival (all P

292 chromosome 11 in the stroma associated with tumor grade were D11S1999 (P = .00055) and D11S1986 (P =

293 growth factor receptor 2 (HER2) status, and tumor grade were then individually correlated with ODRS.

294 es were significantly associated with higher tumor-grade while 3/5 lncRNAs were also associated with

295 RASSF1A methylation increased with tumor grade, while BLU methylation was seen at similar f

296 t cancer biopsies correlated positively with tumor grade, while specimens from patients with benign h

297 The association of tumor grade with recently identified biomarkers indicate

298 re associated with larger tumor size, higher tumor grade with resultant shortened tumor-free survival

299 uman prostate tumor tissues as a function of tumor grade with the highest expression level in metasta

300 k stratification of NENs and compare it with tumor grading (World Health Organization 2010 classifica