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1 macrophages, which make arginase and are not tumoricidal.
2 ecause neoepitope-specific T cells often are tumoricidal.
3 grams both mouse and human macrophages to be tumoricidal.
4 f NK cells, while neutrophils themselves are tumoricidal.
5 and reprogram unique neutrophil subsets with tumoricidal ability and antigen-(cross) presenting funct
6 porter in malignant thyroid cells results in tumoricidal absorbed doses (ADs) delivered by the beta-p
8 factor (TNF) alpha (Ad.Egr-TNF) enhances the tumoricidal action of ionizing radiation in a human epid
9 drug gene therapy to enhance selectively the tumoricidal action of ionizing radiation in human cancer
14 nt enhancement of Kupffer cell (KC)-mediated tumoricidal activity (percentage of specific lysis, 55 +
16 hetic MMP inhibitor, Prinomastat, to enhance tumoricidal activity after PDT, using a mouse mammary tu
19 T cell receptor-redirected T cells exhibited tumoricidal activity against patient-derived pancreatic
20 lls primed in this manner exhibited superior tumoricidal activity against target cells cultured in ei
21 ithin the ocular microenvironment limits CTL tumoricidal activity allowing ocular tumors to progress.
22 ed tumors in vivo by induction of macrophage tumoricidal activity and activation of antitumor activit
24 is-inducing ligand (TRAIL) exhibits specific tumoricidal activity and is under development for cancer
25 eripheral blood immature DCs mediate similar tumoricidal activity as their in vitro counterpart, indi
34 the present study, we demonstrate that this tumoricidal activity is mediated by multiple cytotoxic T
38 ophils are shown to potentially suppress the tumoricidal activity of NK cells, while neutrophils them
39 ab; however, IgA anti-EGFR Abs triggered the tumoricidal activity of PBN and negated the stimulatory
40 ibitors with costimulatory agonists improves tumoricidal activity of T cells but also can lead to off
41 or resetting the M1/M2 ratio, supporting the tumoricidal activity of TAMs for effective melanoma trea
44 XP-524 showed increased potency and superior tumoricidal activity than the benchmark BET inhibitor JQ
45 r model system, M4N demonstrated substantial tumoricidal activity that correlated with a reduction in
46 s PA variant also displayed broad and potent tumoricidal activity to various human tumor cells, espec
47 nitric oxide (NO) in vascular function, host tumoricidal activity, and antiinflammatory effects is we
48 tes appeared to be primarily responsible for tumoricidal activity, because beta-glucan therapeutic re
50 ated with enhancement of splenocyte-mediated tumoricidal activity, whereas the effect of gammaIFN is
51 e pro-inflammatory and have microbicidal and tumoricidal activity, whereas the M2 macrophages are inv
63 t delivered by EBRT, we achieve the targeted tumoricidal AD (80 Gy 2-Gy equieffective dose) while mai
66 involved in the response of cancer cells to tumoricidal agents and found 4 genes required for the re
67 s and sensitizes cancer cells to traditional tumoricidal agents both and The potent and selective pro
68 n mice, systemically delivered NBPs carrying tumoricidal agents reduced the growth of intracranial tr
72 ckade of PGE(2) release, CD8+ T cells become tumoricidal and display an intraepithelial-infiltrating
76 viral pathway in tumors can provoke parallel tumoricidal and immunostimulatory effects that bridge in
78 is responsible in part for the proapoptotic, tumoricidal, and antiproliferative effects of statins in
79 crophages rapidly infiltrated tumors, became tumoricidal, and facilitated the depletion of tumor stro
80 vaccine-induced antibodies mediated in vitro tumoricidal antibody-dependent cellular cytotoxicity (AD
81 man melanomas including metastases, mediates tumoricidal antibody-dependent cellular cytotoxicity and
84 have a distinctive phenotype with increased tumoricidal capability and support the use of immune mod
89 ocesses as this M1 phenotype correlates with tumoricidal capacity, whereas TAMs of M2 phenotype exert
94 lactalbumin made lethal to tumor cells) is a tumoricidal complex of partially unfolded alpha-lactalbu
97 trials have been carried out to reach potent tumoricidal dose levels capable of eradicating tumors wi
98 s provides an innovative way to increase the tumoricidal dose of radiation to tumor sites, whereas sp
99 iotherapy (PULSAR) is designed to administer tumoricidal doses in a pulsed mode with extended interva
100 a phase II/III study using CatmAb revealed a tumoricidal effect associated with reduced VEGF levels,
103 ith low-dose doxorubicin produced a profound tumoricidal effect, resulting in complete eradication of
104 nduced normal tissue injury without reducing tumoricidal effect, thereby increasing the therapeutic r
110 signaling can further enhance recruitment of tumoricidal effector cells, in particular natural killer
113 esenting cells but also into iNOS-expressing tumoricidal effectors that can eradicate immune-evasive
114 ave similar efficacy in remnant ablation and tumoricidal effects and is associated with improved pati
115 eatment planning and, potentially, to better tumoricidal effects and less adverse effects if particle
116 immunotherapeutic approach that shows strong tumoricidal effects in the gut, resulting in an almost t
120 that facilitated tumor cell escape from the tumoricidal effects of tAb; and (ii) acquisition of byst
121 y acquire resistance to the proapoptotic and tumoricidal effects of TNF-alpha, a cytokine that is ele
122 erent tumor cell types led us to compare the tumoricidal effects of TRAIL to those of other TNF famil
123 sion and augment therapeutic benefits beyond tumoricidal effects to harness tumor-specific, durable,
124 actions may benefit GBM patients and lead to tumoricidal effects without sacrificing favorable anti-t
125 -L and rG-L exhibited significantly improved tumoricidal effects, with IC50 values being 120-fold low
131 ase (iNOS)-producing M1 macrophages that are tumoricidal for 4T1 tumor cells; (b) a rapid decrease in
132 ghest therapeutic efficacy, showing balanced tumoricidal function and increased T cell persistence ac
135 ogression and invasion while still retaining tumoricidal function in the presence of tumor-targeting
137 enhances antitumor therapy by improving the tumoricidal function of E7-specific CD8(+) T cells but m
138 difference in their efficiency in mediating tumoricidal functions was seen in response to specific c
142 gineered iNSCs generated EVs loaded with the tumoricidal gene product TRAIL at nearly twice the rate
144 , IgG4 significantly impaired the potency of tumoricidal IgG1 in a human melanoma xenograft mouse mod
145 sponse through activation and recruitment of tumoricidal immune cells such as natural killer T cells.
148 immune regulating cells, conferring a robust tumoricidal immunity surrounding the postsurgical cavity
149 rategy for priming cancer stem cell-specific tumoricidal immunity with broad application in patients
150 he present study show the potential of using tumoricidal/immunostimulatory CpG-siRNA oligonucleotides
153 hibited reduced toxicity and was effectively tumoricidal in vivo in a murine colon carcinoma model.
154 e of intraperitoneal instillation of various tumoricidals in order to reduce the risk of port site se
155 thin the tumour immune microenvironment with tumoricidal M1 and tumour-protective M2 phenotypes could
156 lated by IL-13 and requires the induction of tumoricidal M1 macrophages and lymphocytes combined with
159 neuploidy while skewing macrophages toward a tumoricidal 'M1-like' phenotype based on markers and sho
162 din is a prodrug that is anabolized into its tumoricidal metabolite, gliocidin-adenine dinucleotide (
163 munogenic antigen presentation that confer a tumoricidal microenvironment highly infiltrated by tumor
168 ed macrophages have the potential to develop tumoricidal NK cell-like functions that may be exploited
169 morigenic role, macrophages can also display tumoricidal (or M1-like) behavior, revealing that macrop
174 ible nitric oxide synthase (iNOS)-expressing tumoricidal phenotypes that-together with CD4(+) and CD8
176 of the present study was to investigate the tumoricidal potential of combining the apoptosis-inducin
180 ic radiosurgery (SSRS), allowing delivery of tumoricidal radiation doses with sparing of nearby organ
181 omise, but as yet has been unable to deliver tumoricidal radiation doses without unacceptable toxicit
182 hytherapy (HDR) was used to deliver adequate tumoricidal radiation while preserving bone and organ gr
183 perimental treatment approach that elicits a tumoricidal response against diffuse, solid i.p. disease
185 model, resulting in a significantly enhanced tumoricidal response to CPT-11 via increased induction o
186 the control group and significantly improved tumoricidal response to treatment compared with all trea
187 t zinc protoporphyrin (ZnPP) induce a potent tumoricidal response via a mutual potentiating mechanism
188 rapy (IM862 or EMAP-II) and PDT had improved tumoricidal responses compared with individual treatment
189 ction and promote the engagement of adaptive tumoricidal responses is likely to lead to the developme
190 indicate that monocytes can be activated for tumoricidal responses through a membrane structure assoc
196 DC vaccines in stimulating the production of tumoricidal T cells, with broad implications for many of
197 tion of NO-producing M1 macrophages that are tumoricidal, the reduction in MSC levels to baseline aft
198 study demonstrates that unlike conventional tumoricidal therapies, which rely on effective p53 targe
202 lated radiation therapy (IG-IMRT) allows for tumoricidal treatment of traditionally radioresistant ca
204 ges, which contain high levels of NO and are tumoricidal, whereas BALB/c mice produce M2 macrophages,