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1 macrophages, which make arginase and are not tumoricidal.
2 ecause neoepitope-specific T cells often are tumoricidal.
3 grams both mouse and human macrophages to be tumoricidal.
4 f NK cells, while neutrophils themselves are tumoricidal.
5 and reprogram unique neutrophil subsets with tumoricidal ability and antigen-(cross) presenting funct
6 porter in malignant thyroid cells results in tumoricidal absorbed doses (ADs) delivered by the beta-p
7 ctive use of celecoxib enhances PDT-mediated tumoricidal action in an in vivo tumor model.
8 factor (TNF) alpha (Ad.Egr-TNF) enhances the tumoricidal action of ionizing radiation in a human epid
9 drug gene therapy to enhance selectively the tumoricidal action of ionizing radiation in human cancer
10 p to 70% of patients, and suggest a possible tumoricidal action.
11 tumor cell-derived GM-CSF in recruitment and tumoricidal activation of tissue macrophages.
12                In this study we examined the tumoricidal activities of the type I receptors for IgG (
13 y reprogramming macrophages to sustain their tumoricidal activities.
14 nt enhancement of Kupffer cell (KC)-mediated tumoricidal activity (percentage of specific lysis, 55 +
15 wed with a uniquely potent MHC nonrestricted tumoricidal activity across several species.
16 hetic MMP inhibitor, Prinomastat, to enhance tumoricidal activity after PDT, using a mouse mammary tu
17 f the TNF superfamily that exhibits specific tumoricidal activity against a variety of tumors.
18 eosinophils exerted dose- and time-dependent tumoricidal activity against Colo-205 cells.
19 T cell receptor-redirected T cells exhibited tumoricidal activity against patient-derived pancreatic
20 lls primed in this manner exhibited superior tumoricidal activity against target cells cultured in ei
21 ithin the ocular microenvironment limits CTL tumoricidal activity allowing ocular tumors to progress.
22 ed tumors in vivo by induction of macrophage tumoricidal activity and activation of antitumor activit
23 -DG potentiates the effect of (64)Cu-ATSM on tumoricidal activity and animal survival.
24 is-inducing ligand (TRAIL) exhibits specific tumoricidal activity and is under development for cancer
25 eripheral blood immature DCs mediate similar tumoricidal activity as their in vitro counterpart, indi
26                      As OA lacks independent tumoricidal activity at concentrations equimolar to HAML
27             Moreover, these macrophages lose tumoricidal activity but become extremely proangiogenic,
28 iferation, intestinal microbiota effects, or tumoricidal activity by the adaptive immune system.
29                                         This tumoricidal activity depended strictly on tumor cell-sur
30 mma-dependent induction of antimicrobial and tumoricidal activity in macrophages.
31                    We also observed enhanced tumoricidal activity in mice with TSA tumors containing
32  the latter markers associated with elevated tumoricidal activity in vitro.
33        These macrophages possess nonspecific tumoricidal activity in vivo as immune distinct MCA207 t
34  the present study, we demonstrate that this tumoricidal activity is mediated by multiple cytotoxic T
35 e immune cell phenotypes while impairing the tumoricidal activity of immune cells.
36           The released NO contributes to the tumoricidal activity of macrophages, whereas polyamines
37                                 The enhanced tumoricidal activity of nano-photosensitizers with Y-90
38 ophils are shown to potentially suppress the tumoricidal activity of NK cells, while neutrophils them
39 ab; however, IgA anti-EGFR Abs triggered the tumoricidal activity of PBN and negated the stimulatory
40 ibitors with costimulatory agonists improves tumoricidal activity of T cells but also can lead to off
41 or resetting the M1/M2 ratio, supporting the tumoricidal activity of TAMs for effective melanoma trea
42                                 However, the tumoricidal activity of TCR-modified T cells may be limi
43 vored generation of Th2 cells that had lower tumoricidal activity than Th1 cells.
44 XP-524 showed increased potency and superior tumoricidal activity than the benchmark BET inhibitor JQ
45 r model system, M4N demonstrated substantial tumoricidal activity that correlated with a reduction in
46 s PA variant also displayed broad and potent tumoricidal activity to various human tumor cells, espec
47 nitric oxide (NO) in vascular function, host tumoricidal activity, and antiinflammatory effects is we
48 tes appeared to be primarily responsible for tumoricidal activity, because beta-glucan therapeutic re
49 umor-reactive lymphocytes and exerted direct tumoricidal activity, both in vivo and in situ.
50 ated with enhancement of splenocyte-mediated tumoricidal activity, whereas the effect of gammaIFN is
51 e pro-inflammatory and have microbicidal and tumoricidal activity, whereas the M2 macrophages are inv
52 xicity to normal tissue but broad and potent tumoricidal activity.
53 uced, but not of IFN-gamma-induced, monocyte tumoricidal activity.
54 -gamma, P < .01) but not lymphocyte-mediated tumoricidal activity.
55 ted CD8(+) T (T(ex)) cells that have limited tumoricidal activity.
56 that reduces immunopathology but compromises tumoricidal activity.
57 ate and adaptive immunity contributes to the tumoricidal activity.
58 e-threatening CRS while enhancing CAR T cell tumoricidal activity.
59 major factor responsible for Th-1-induced DC tumoricidal activity.
60  increased susceptibility to immune-mediated tumoricidal activity.
61  virus for tumor therapies due to its potent tumoricidal activity.
62  T cells, but this encounter opposes NK-cell tumoricidal activity.
63 t delivered by EBRT, we achieve the targeted tumoricidal AD (80 Gy 2-Gy equieffective dose) while mai
64 thrax toxin from a highly lethal to a potent tumoricidal agent.
65 ng T lymphocytes to produce a broad-spectrum tumoricidal agent.
66  involved in the response of cancer cells to tumoricidal agents and found 4 genes required for the re
67 s and sensitizes cancer cells to traditional tumoricidal agents both and The potent and selective pro
68 n mice, systemically delivered NBPs carrying tumoricidal agents reduced the growth of intracranial tr
69                           In addition to new tumoricidal agents, parallel work is also being conducte
70 ide is an immunomodulatory agent with proven tumoricidal and antiproliferative activity in MCL.
71 crophage activation, which limits the cell's tumoricidal and bactericidal capacities.
72 ckade of PGE(2) release, CD8+ T cells become tumoricidal and display an intraepithelial-infiltrating
73                                     Both the tumoricidal and growth-promoting activities from macroph
74          Taken together, arming T cells with tumoricidal and immune-potentiating MDA-7/IL24 confers n
75                             Lenalidomide has tumoricidal and immunomodulatory activity against multip
76 viral pathway in tumors can provoke parallel tumoricidal and immunostimulatory effects that bridge in
77 e being the evaluable outcome parameters for tumoricidal and survival studies, respectively.
78 is responsible in part for the proapoptotic, tumoricidal, and antiproliferative effects of statins in
79 crophages rapidly infiltrated tumors, became tumoricidal, and facilitated the depletion of tumor stro
80 vaccine-induced antibodies mediated in vitro tumoricidal antibody-dependent cellular cytotoxicity (AD
81 man melanomas including metastases, mediates tumoricidal antibody-dependent cellular cytotoxicity and
82               We thus sought to evaluate the tumoricidal benefits of systemic decorin on a triple-neg
83 ent data apparently explain the mechanism of tumoricidal beta-glucans used for immunotherapy.
84  have a distinctive phenotype with increased tumoricidal capability and support the use of immune mod
85 and 3) differentiating into macrophages with tumoricidal capability.
86  SHP-1 abundance or activity may enhance the tumoricidal capacity of NK cells.
87 targeting mAb, unmasking an underappreciated tumoricidal capacity of TAMs.
88 ome this suppression and thereby augment the tumoricidal capacity of tumor-reactive lymphocytes.
89 ocesses as this M1 phenotype correlates with tumoricidal capacity, whereas TAMs of M2 phenotype exert
90 mma and anti-CD40 antibodies, reducing their tumoricidal capacity.
91 ctivation, proinflammatory polarization, and tumoricidal capacity.
92 r Ag-specific precursor frequency to reach a tumoricidal cell density.
93 eg numbers and a concomitant accumulation of tumoricidal cells such as CD8+NKG2D+ and NK cells.
94 lactalbumin made lethal to tumor cells) is a tumoricidal complex of partially unfolded alpha-lactalbu
95                           Upon CTL transfer, tumoricidal concentrations of NO were only produced by s
96 lar in nature, composed of tumor-seeking and tumoricidal domains.
97 trials have been carried out to reach potent tumoricidal dose levels capable of eradicating tumors wi
98 s provides an innovative way to increase the tumoricidal dose of radiation to tumor sites, whereas sp
99 iotherapy (PULSAR) is designed to administer tumoricidal doses in a pulsed mode with extended interva
100 a phase II/III study using CatmAb revealed a tumoricidal effect associated with reduced VEGF levels,
101                       Here, we show that the tumoricidal effect of E4orf4 is typified by changes in n
102                                          The tumoricidal effect was also assessed ex vivo by immunohi
103 ith low-dose doxorubicin produced a profound tumoricidal effect, resulting in complete eradication of
104 nduced normal tissue injury without reducing tumoricidal effect, thereby increasing the therapeutic r
105  seen with MTX treatment while enhancing its tumoricidal effect.
106 vation of innate immunity can lead to direct tumoricidal effect.
107  cells, however, gelonin exerts only limited tumoricidal effect.
108 emonstrate a similar mutual potentiation and tumoricidal effect.
109                         We also examined the tumoricidal effectiveness of combining PDT with the sele
110 signaling can further enhance recruitment of tumoricidal effector cells, in particular natural killer
111                 CD8+ CTL are the predominant tumoricidal effector cells.
112 tumor-infiltrating T cells, which suppresses tumoricidal effector functions.
113 esenting cells but also into iNOS-expressing tumoricidal effectors that can eradicate immune-evasive
114 ave similar efficacy in remnant ablation and tumoricidal effects and is associated with improved pati
115 eatment planning and, potentially, to better tumoricidal effects and less adverse effects if particle
116 immunotherapeutic approach that shows strong tumoricidal effects in the gut, resulting in an almost t
117  and we explored its capacity to enhance the tumoricidal effects of doxorubicin.
118                                              Tumoricidal effects of lenalidomide are associated with
119 eclinical models its capacity to enhance the tumoricidal effects of paclitaxel and doxorubicin.
120  that facilitated tumor cell escape from the tumoricidal effects of tAb; and (ii) acquisition of byst
121 y acquire resistance to the proapoptotic and tumoricidal effects of TNF-alpha, a cytokine that is ele
122 erent tumor cell types led us to compare the tumoricidal effects of TRAIL to those of other TNF famil
123 sion and augment therapeutic benefits beyond tumoricidal effects to harness tumor-specific, durable,
124 actions may benefit GBM patients and lead to tumoricidal effects without sacrificing favorable anti-t
125 -L and rG-L exhibited significantly improved tumoricidal effects, with IC50 values being 120-fold low
126 ein expression levels, as well as remarkable tumoricidal effects.
127 , but it has the potential to interfere with tumoricidal effects.
128 f chemotherapy to tumor sites, enhancing its tumoricidal effects.
129 port rate constants along with having direct tumoricidal effects.
130 tumors present an urgent need to augment its tumoricidal efficacy.
131 ase (iNOS)-producing M1 macrophages that are tumoricidal for 4T1 tumor cells; (b) a rapid decrease in
132 ghest therapeutic efficacy, showing balanced tumoricidal function and increased T cell persistence ac
133 l costimulation induced CD4 T cell-dependent tumoricidal function in a mouse melanoma model.
134 effectively blocked both MAPK activation and tumoricidal function in NK cells.
135 ogression and invasion while still retaining tumoricidal function in the presence of tumor-targeting
136                                    Thus, the tumoricidal function of CR3-binding polysaccharides such
137  enhances antitumor therapy by improving the tumoricidal function of E7-specific CD8(+) T cells but m
138  difference in their efficiency in mediating tumoricidal functions was seen in response to specific c
139 y mediators and metabolic inhibitors, having tumoricidal functions.
140 and nonspecific IgG4 inhibited IgG1-mediated tumoricidal functions.
141 ests that dendritic cells may mediate direct tumoricidal functions.
142 gineered iNSCs generated EVs loaded with the tumoricidal gene product TRAIL at nearly twice the rate
143 the full-length hTERT, effectively stimulate tumoricidal, hTERT-specific CTLs.
144 , IgG4 significantly impaired the potency of tumoricidal IgG1 in a human melanoma xenograft mouse mod
145 sponse through activation and recruitment of tumoricidal immune cells such as natural killer T cells.
146 ting gene-transduced cancer vaccines induces tumoricidal immune responses.
147                    Radiotherapy (RT)-induced tumoricidal immunity is severely limited when tumors are
148 immune regulating cells, conferring a robust tumoricidal immunity surrounding the postsurgical cavity
149 rategy for priming cancer stem cell-specific tumoricidal immunity with broad application in patients
150 he present study show the potential of using tumoricidal/immunostimulatory CpG-siRNA oligonucleotides
151         It is most practical, tolerable, and tumoricidal in its most potent form treating tumors in t
152       NKG2D(+) but not NKG2D(-) NK cells are tumoricidal in vitro, and in vivo they selectively traff
153 hibited reduced toxicity and was effectively tumoricidal in vivo in a murine colon carcinoma model.
154 e of intraperitoneal instillation of various tumoricidals in order to reduce the risk of port site se
155 thin the tumour immune microenvironment with tumoricidal M1 and tumour-protective M2 phenotypes could
156 lated by IL-13 and requires the induction of tumoricidal M1 macrophages and lymphocytes combined with
157 notype, thereby inhibiting the generation of tumoricidal M1 macrophages.
158 ich induce human mMDSC to differentiate into tumoricidal M1-like macrophages.
159 neuploidy while skewing macrophages toward a tumoricidal 'M1-like' phenotype based on markers and sho
160                                     Although tumoricidal macrophages are a necessary component of imm
161         Thus, this study further defines the tumoricidal mechanism of the mAbs and provides strong ev
162 din is a prodrug that is anabolized into its tumoricidal metabolite, gliocidin-adenine dinucleotide (
163 munogenic antigen presentation that confer a tumoricidal microenvironment highly infiltrated by tumor
164 rt immunosuppressive tumours to immunogenic, tumoricidal microenvironments.
165           Granulysin is an antimicrobial and tumoricidal molecule expressed in granules of CTL and NK
166 roduction of IFN-gamma capable of activating tumoricidal Mphi.
167            The immune effector monocytes and tumoricidal neutrophils target disseminated tumor cells
168 ed macrophages have the potential to develop tumoricidal NK cell-like functions that may be exploited
169 morigenic role, macrophages can also display tumoricidal (or M1-like) behavior, revealing that macrop
170  the cytokine IL-12 which activates multiple tumoricidal pathways.
171                                              Tumoricidal penetration depth of temoporfin-PDT (T-PDT)
172 n create a potentially valuable new class of tumoricidal peptides.
173 e recapitulates the late-stage activated and tumoricidal phenotype in vitro.
174 ible nitric oxide synthase (iNOS)-expressing tumoricidal phenotypes that-together with CD4(+) and CD8
175                              We compared the tumoricidal potency of ultra-high dose rate and conventi
176  of the present study was to investigate the tumoricidal potential of combining the apoptosis-inducin
177                       Only R24 augmented the tumoricidal potential of fresh canine peripheral blood m
178 major histocompatibility complex-independent tumoricidal potential.
179 es strategies to skew neutrophils to acquire tumoricidal properties.
180 ic radiosurgery (SSRS), allowing delivery of tumoricidal radiation doses with sparing of nearby organ
181 omise, but as yet has been unable to deliver tumoricidal radiation doses without unacceptable toxicit
182 hytherapy (HDR) was used to deliver adequate tumoricidal radiation while preserving bone and organ gr
183 perimental treatment approach that elicits a tumoricidal response against diffuse, solid i.p. disease
184           beta-Glucan enhancement of the mAb tumoricidal response did not occur in mice deficient in
185 model, resulting in a significantly enhanced tumoricidal response to CPT-11 via increased induction o
186 the control group and significantly improved tumoricidal response to treatment compared with all trea
187 t zinc protoporphyrin (ZnPP) induce a potent tumoricidal response via a mutual potentiating mechanism
188 rapy (IM862 or EMAP-II) and PDT had improved tumoricidal responses compared with individual treatment
189 ction and promote the engagement of adaptive tumoricidal responses is likely to lead to the developme
190 indicate that monocytes can be activated for tumoricidal responses through a membrane structure assoc
191 nistration of ganciclovir, could enhance the tumoricidal responsiveness of PDT.
192 HL treatment by remodeling TME to enable the tumoricidal roles of TAMs.
193                                         This tumoricidal synergy is now being tested in a phase I-II
194 croenvironments that inhibit the activity of tumoricidal T and NK cells.
195       However, WT-1 peptides known to induce tumoricidal T cells are few.
196 DC vaccines in stimulating the production of tumoricidal T cells, with broad implications for many of
197 tion of NO-producing M1 macrophages that are tumoricidal, the reduction in MSC levels to baseline aft
198  study demonstrates that unlike conventional tumoricidal therapies, which rely on effective p53 targe
199  as well as in the assessment of response to tumoricidal therapies.
200 sic cell death program of ICE as a means for tumoricidal therapy in a rat brain tumor model.
201                 Local application of heat is tumoricidal; therefore, the authors investigated a novel
202 lated radiation therapy (IG-IMRT) allows for tumoricidal treatment of traditionally radioresistant ca
203                                 ADT was only tumoricidal when the tumor cells expressed high levels o
204 ges, which contain high levels of NO and are tumoricidal, whereas BALB/c mice produce M2 macrophages,

 
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