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3 and repair accompanied by complex remodeling typifies a somatic stem/progenitor cell-mediated process
4 dox regulation and immunomodulatory proteins typify a proteotype associated with an aggressive cancer
8 e leukemia (MLL) gene with multiple partners typify acute leukemias of infancy as well as therapy-rel
15 establishment of histone modifications that typify an activated chromatin state at pluripotency loci
17 andard" reptantian hemiellipsoid bodies that typify Astacidea and Achelata are extreme examples of di
18 s of SOD activity and downstream events that typify asthma, including apoptosis and shedding of the a
19 ces at which g5p initiates assembly might be typified better by DNA hairpins than by G-quadruplexes.
20 subunit-selective NMDA receptor antagonists, typified by (E)-4-(6-methoxy-2-(3-nitrostyryl)-4-oxoquin
21 identified for the first time Nur77 agonists typified by 1,1-bis(3-indolyl)-1-(p-anisyl)methane that
23 rom the Wacker oxidation of internal alkenes typified by 5-(but-2-enyl)pyrrolidin-2-ones and 6-(but-2
25 tering analyses show that the Zf-GRF fold is typified by a crescent-shaped ssDNA binding claw that is
27 es were accompanied by synaptic alterations, typified by a decrease in synaptic plasticity and a redu
28 is on preservation of neurological function, typified by a general paradigm of maximally safe cytored
29 ocarcinoma (PDA) is an aggressive malignancy typified by a highly stromal and weakly immunogenic tumo
30 sed by Vibrio cholerae El Tor O1 strains are typified by a large number of asymptomatic carriers who
32 f central nervous system infectious diseases typified by a pathogenic inflammatory component through
33 yndrome, a devastating neurological disorder typified by a period of apparently normal development fo
35 rogression to stem cell differentiation, are typified by a prolonged cellular response to a transient
36 gration and maturation (LIMK1 and CLIP2), is typified by a remarkable hypersocial but anxious persona
38 e transition from fetal to postnatal life is typified by a reversal of direction, from demethylation
39 ease (AD) is a progressive amnestic dementia typified by abnormal modifications of the microtubule (M
42 PS is coupled to profound metabolic changes, typified by accumulation of the TCA cycle intermediates
43 ce via Grubbs metathesis to produce peptides typified by acetyl-A-(Sar)3-(88)VVGLXLIZXGVVV(100)-KKK-N
45 vascular disease; diabetic cardiomyopathy is typified by alterations in cardiac morphology and functi
49 evealed a unique genetic fingerprint that is typified by an increase in C:G-->A:T and A:T-->T:A trans
51 is mediated by a family of DNA glycosylases typified by Arabidopsis ROS1 (repressor of silencing 1).
53 thiotransferases, the other two of which are typified by Bacillus subtilis YqeV and Methanococcus jan
54 vesicles carrying different sets of cargoes typified by Bgl2p and invertase are delivered to the pla
55 C accounting for more than 80% of cases, are typified by biallelic inactivation of the von Hippel-Lin
57 ed by autosomal recessive mutations in CLN3, typified by blindness, seizures, progressive cognitive a
58 amond syndrome (SDS) is a recessive disorder typified by bone marrow failure and predisposition to he
61 the binding of halogen-incorporated benzenes typified by C(6)F(5)X, where X=H, F, Cl, Br or I, and C(
62 3 contributed to the full induction of some (typified by c-fos) but not all (typified by c-myc) immed
63 ion of some (typified by c-fos) but not all (typified by c-myc) immediate early gene expression, but
64 s of C2 domains including those respectively typified by C2 domains in the Aida (axin interactor, dor
67 o an embryonic alternative splicing program, typified by CD44v3 overexpression, represents a previous
69 ents presented remarkably similar phenotypes typified by cerebellar and cerebral atrophy, seizures, i
70 ltogether, the findings indicate that PAH is typified by changes in metabolic pathways that are prima
71 how that the tumoricidal effect of E4orf4 is typified by changes in nuclear dynamics that depend on i
72 ignificant proteo-metabolomic alteration(s), typified by changes in the lipidome with corresponding u
73 y contribute to the impaired decision-making-typified by chronic substance abuse and relapse-observed
78 nbeard interactions in a vertebrate that are typified by cycles of greenbeard mutualism interspersed
80 [aOR], 2.13; 95% CI, 1.37-3.30; P=.001) and typified by dermoscopic regression (aOR, 2.13; 95% CI, 1
81 l syndrome (BBS) is a multisystemic disorder typified by developmental and progressive degenerative d
83 s underlying this acquired unresponsiveness, typified by diminished functional responses to TLR or CD
84 ce of two types of enhancer units within SEs typified by distinctive CpG methylation dynamics in embr
85 ming erases somatic epigenetic signatures-as typified by DNA methylation or histone modification at s
87 eptidase-like type II transmembrane proteins typified by DPPX-S, and cytoplasmic Ca(2+) binding prote
88 is caused by mutations in keratin genes and typified by dystrophic lesions affecting nails, glands,
89 ause pachyonychia congenita (PC), a disorder typified by dystrophic nails, painful hyperkeratotic cal
90 ven though they range from pluripotent cells-typified by embryonic stem cells, which are capable of v
91 al or dsRNA/actinomycin D-induced apoptosis, typified by enhanced cytochrome c release from the mitoc
93 y, with significantly larger brain abscesses typified by exaggerated edema and necrosis in MyD88 KO a
94 ng displayed exacerbated airway remodelling, typified by excess peribronchiolar collagen deposition.
95 ed population of CD8(+)CD122(+)CD44(+) ILLs, typified by expression of the T-box transcription factor
96 elicobacter pylori phase variable gene modH, typified by gene HP1522 in strain 26695, encodes a N(6)-
97 ent of a first generation of virtual globes, typified by Google Earth, that achieved many but not all
99 V Env also develop transformed phenotype, as typified by growth in soft agar and Matrigel invasion.
100 dermal hyperplasia and chronic inflammation, typified by hair degeneration and loss of body fat.
102 mounted vigorous secondary immune responses typified by high avidity measles immunoglobulin G antibo
104 ith oncogenic human papillomaviruses (HPVs), typified by HPV type 16 (HPV16), is a necessary cause of
106 an essential multifunctional protein that is typified by ICP27 encoded by Herpes Simplex Virus 1.
107 facial cutaneous (NCFC) syndromes, which are typified by impaired neurocognitive abilities that are r
109 f6b null mice showed enhanced decompensation typified by increased heart weight, pulmonary edema and
110 ed inflammatory response to cigarette smoke, typified by increased levels of cyclooxygenase-2 (COX-2)
111 otic changes in the matrix microenvironment, typified by increased type I and III collagens and fibro
112 mal infection with pyogenic bacteria and are typified by inflammation and edema, which frequently res
115 ivatives from the indole carboxamide series, typified by JNJ 7777120, and incorporating knowledge fro
116 e plasma membrane in many types of cells, as typified by junctophilin-2 (JPH2), which is necessary fo
117 immune tolerance in the healthy intestine is typified by lamina propria T cell (LPT) functional hypor
118 s the progression of human breast carcinomas typified by loss of p53 integrity, development of centro
119 a with vitamin E deficiency (AVED) syndrome, typified by low vitamin E levels and a plethora of neuro
120 s in KPTN, encoding kaptin, cause a syndrome typified by macrocephaly, neurodevelopmental delay, and
122 ubgroups of MTTases have been characterized, typified by MiaB, which modifies N(6)-isopentenyladenosi
128 at have a common set of 12 proteins, but are typified by mutually exclusive RNase III endonucleases w
129 treatment, leads to hippocampus dysfunction typified by neurodegeneration, inflammation, altered neu
130 in a variety of diseases, many of which are typified by neurological dysfunction and/or increased ge
132 se of solid-tissue neoplasms, MM genomes are typified by numerous structural and numerical chromosoma
133 ension (PAH) is a rare, progressive disorder typified by occlusion of the pulmonary arterioles owing
135 h M a transition metal and X a chalcogen) is typified by one-dimensional (1D) chains weakly bound tog
136 embryonic alternative splice isoform program typified by overexpression of CD44 transcript variant 3,
137 cell responses; and third, solid cancers are typified by phenotypic diversity and thus include cells
139 assical Werner-like premature aging syndrome typified by premature death, hair graying, alopecia, ost
140 H3K27me3 chromatin, while in other species, typified by Pristionchus pacificus, piRNAs are found wit
141 tive lysosomal cholesterol storage disorder, typified by progressive cognitive and motor function imp
142 ointing, often resulting in short remissions typified by rapid outgrowth of drug-resistant clones.
143 cator of cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, increased serum IgE le
145 m exercise affects stem cell aging, which is typified by reduced proliferative and differentiative ca
146 rior inhibition in more mature adulthood was typified by reduced segregation in the default network w
147 iggers gradual epithelium dedifferentiation, typified by reduction of RPE-characteristic proteins and
149 ry phenotype and functional characteristics; typified by reductions in NF-kappaBp65, TNF-alpha, and I
150 by chronic sun-exposure, and dermoscopically typified by regression represent best indications for th
151 Toll-like receptor 2-agonistic lipopeptides typified by S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-R-cys
153 cts which persist into adult stages that are typified by smaller brains and eyes and abnormalities in
155 cence (OIS) is a tumor-suppressive mechanism typified by stable proliferative arrest, a persistent DN
156 uman MAIT cells are hyperresponsive to SAgs, typified by staphylococcal enterotoxin B (SEB); ii) the
157 sa simplex (EBS) is a rare genetic condition typified by superficial bullous lesions following incide
158 osa (EB) simplex is a rare genetic condition typified by superficial bullous lesions that result from
159 ngs to human AKI remains a barrier, which is typified by the absence of effective therapeutic agents.
160 ominant polycystic kidney disease (ADPKD) is typified by the accumulation of fluid-filled cysts and a
161 E2 allele modifies the natural history of AD typified by the age of onset in E280A mutation carriers.
162 rocessing pathways of kinetoplastid protists typified by the causative agent of African sleeping sick
163 hat deviate from these natural sequences, as typified by the charge-clustered peptide KKKKKKAAFAAWAAF
164 rms of cognitive impairment in older people (typified by the concept of mild cognitive impairment) ha
171 elial cells become mesenchymal cells, and is typified by the generation of neural crest cells from th
172 rated brain abscess encapsulation, which was typified by the heightened expression of fibronectin and
173 l record of the terminal Ediacaran Period is typified by the iconic index fossil Cloudina and its rel
178 associated with normal changes of pregnancy, typified by the need to differentiate whether gestationa
179 ns are the most common type of large motion, typified by the opening and closing of enzymes around th
181 ease (AD) is a progressive amnestic disorder typified by the pathological misfolding and deposition o
182 s are a clinically diverse group of diseases typified by the pathological self-assembly of the microt
187 mmalian immune responses to LPS exposure are typified by the robust induction of NF-kappaB and IFN-be
188 lecular explanations for these associations, typified by the role of short-chain fatty acids, product
190 in behaviour from the simple, linear systems typified by the traditional model of pneumonia pathogene
191 is most closely related to the class of PBPs typified by the vitamin B(12) (BtuF) and iron-hydroxamat
192 e a type of plant growth promoting bacteria, typified by their ability to fix nitrogen for their plan
196 f bladder cancers coalesced into one subtype typified by TP53 alterations, TP63 amplifications, and h
198 ithelial-to-mesenchymal transition (EMT), as typified by tubular loss of E-cadherin and acquisition o
199 on chromosome 7 (7q11.23) and is clinically typified by two cognitive/behavioural hallmarks: marked
200 enveloped viruses categorized as class I are typified by two distinct heptad repeat domains within th
201 nature, including the PD(D/E)XK superfamily (typified by type II restriction endonucleases and many r
202 entally identified genetic variants which is typified by variants found in genes associated with sudd
203 described in humans, pro-angiogenic isoforms typified by VEGF-A165a, and anti-angiogenic isoforms typ
206 lation of karyotypic abnormalites that often typify cancer cells, including end-to-end chromosome fus
207 e gut structure, and fast transit times that typify caterpillar digestive physiology may prevent micr
208 c, functional, and molecular properties that typify central memory T cells were expressed within 48 h
209 er syndrome (GSS) is a genetic prion disease typified clinically by the development of progressive at
210 ses knowledge about both the properties that typify concepts (e.g. robins, like all birds, have wings
212 at the vicinity of a polarized actin network typifying E4orf4 action, in a manner controlled by SFK a
215 inding particle defined in this study (RESC) typify enzymatic and substrate binding macromolecular co
216 chemoresistant disease after primary therapy typifies epithelial ovarian cancer and may be attributab
218 ce the social and cultural shifts thought to typify globalization, and an analysis of their experienc
219 iological, and gene expression profiles that typify glutamatergic forebrain neurons and are competent
221 wasting and atrophy of skeletal muscle that typify heart failure were not observed in these heart-sp
222 ost-translational histone modifications that typify heterochromatin are enriched in the vicinity of t
224 ot, sunny environments; small-leaved species typify hot, sunny environments only in arid conditions;
227 A-3, RUNX1, C-MYB transcription factors that typify initial stages of definitive hematopoiesis origin
228 terminus of VP30 with sequence features that typify intrinsically disordered regions and a putative R
229 for the formation of membrane ruffles which typify late closure stages, whereas Cdc42 is required fo
232 astrocytomas with KIAA1549-BRAF fusion genes typifying low-grade astrocytomas and (V600E)BRAF alterat
233 differentiated by sex, with androgen biases typifying males and estrogen biases typifying females.
236 SRP-dependent co-translational pathway that typifies most integral membrane proteins; instead, post-
237 hough both spectral contrast and harmonicity typify natural sounds, they may differ in salience for c
238 nectivity during successful memory retrieval typified network topology, with individual participant p
240 Thus, for instance, (1C+1C) processes are typified notably by Alder-ene type reactions taking plac
241 structural and functional conservation that typifies other imprinted domains and suggest that the PE
243 chitecturally defective, leaky blood vessels typify pathologic angiogenesis induced by vascular endot
245 the rapidly fatal gram-negative sepsis that typifies plague is a consequence of the high threshold b
246 n, is part of a bivalent chromatin mark that typifies poised developmental genes in embryonic stem ce
247 metric mobilization of actin and myosin that typifies polarity and ultimately directs chemotaxis.
248 tragic, much-publicized case of Jahi McMath typifies potential problems that can be encountered with
255 at domed centers called hemiellipsoid bodies typifying reptantian crustaceans, such as lobsters and c
256 s of the two major diterpenes present in two typified rosemary extracts affects their levels of depos
260 descriptive comparison of p-values that has typified similar cross-population fine-mapping studies t
261 d less mitochondrial iron; these differences typify slightly older hearts, perhaps reflecting the bur
262 s from type specimens provide a new tool for typifying species in the Gelidiales and that there is an
264 ma 2 and alpha 4 beta 3 delta receptors that typify synaptic- and extrasynaptic-type receptors expres
265 tennal lobe loss and calycal regression also typify taxa with short nonfeeding adults, in which olfac
269 ts regained the suppressed maze-running that typified the original habit, and, simultaneously, the mo
273 M sleep time while increased slow wave sleep typifies the inactive phase, findings that have implicat
274 cases quantification, of the processes that typifies the myocardial metabolic remodeling in diabetic
276 whole drop, leading to its milky color that typifies the so-called "Ouzo effect." Once all ethanol h
281 M1 and M2 tumor-associated macrophages (TAM) typify the complexity of macrophage function in cancer.
285 proving that the yeast-inoculating form may typify the odor and flavor descriptors of the green beer
286 IL-4 was able to induce expression of genes typifying the M2 phenotype and peroxisome proliferator a
287 ion, a granular layer and a low-density zone typifying the periplasmic space of gram-positive bacteri
288 est that a suite of morphological characters typifying the Tigriopus brain reflect a ground pattern o
290 bolite 1,3-bisphosphoglyceric acid (1,3-BPG) typifies this class of metabolites, and, despite its cen
293 was void of the set of four guanine repeats typifying thrombin aptamers and, thus, highlights the be
294 ching the seven broad and narrow motifs that typify tropomyosin's twisting superhelical coiled-coil t
295 y responsive to elevated eIF4F activity that typifies tumorigenesis underscores the critical role of
298 impairment and hypersocial personality that typify Williams syndrome, the Williams syndrome cohort e