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1 tes, the N-end rule pathway is a part of the ubiquitin system.
2 ther or not p53 is itself a substrate of the ubiquitin system.
3 of the receptor protein as substrate for the ubiquitin system.
4 ic regulation of mitochondrial import by the ubiquitin system.
5 iquitination is an integral component of the ubiquitin system.
6 ty of limiting metabolic enzymes through the ubiquitin system.
7  as an important regulatory layer within the ubiquitin system.
8 mechanisms to manipulate or subvert the host ubiquitin system.
9 ic AAA+ ATPase with diverse functions in the ubiquitin system.
10 igase substrate receptors independent of the ubiquitin system.
11 quitination, are important regulators of the ubiquitin system.
12 cificity gives fundamental insights into the ubiquitin system.
13 proteins and are hence key regulators of the ubiquitin system.
14 nserved regulation of Notch signaling by the ubiquitin system.
15 and mechanisms of substrate targeting by the ubiquitin system.
16 as a DAT interacting protein using the split ubiquitin system.
17 allows for the remarkable versatility of the ubiquitin system.
18 activities of kinases, phosphatases, and the ubiquitin system.
19 reted LLO is targeted for degradation by the ubiquitin system.
20 dent of VHL and p53 and does not require the ubiquitin system.
21 rades proteins tagged for destruction by the ubiquitin system.
22 o physically interact with Gpa1 in the split-ubiquitin system.
23 on of proteins marked for destruction by the ubiquitin system.
24 nct mechanism for substrate targeting in the ubiquitin system.
25  of proteins targeted for proteolysis by the ubiquitin system.
26 many otherwise dissimilar E3 proteins of the ubiquitin system.
27 dvance and the mechanics of targeting by the ubiquitin system.
28 ify the relevant targeting components of the ubiquitin system.
29 le pathway is one proteolytic pathway of the ubiquitin system.
30 A libraries using yeast-two-hybrid and split-ubiquitin systems.
31 actor at the crossroads between the SUMO and ubiquitin systems.
32 ning the highly characterized bradykinin and ubiquitin systems.
33              Specifically, we review how the ubiquitin system affects expression of genes or abundanc
34                                          The ubiquitin system affects plant health, reproduction, and
35 by the ubiquitin system, and discuss how the ubiquitin system affects proteins involved in pathogen o
36 using a high-resolution CRISPR screen of the ubiquitin system after IR, we systematically uncover gen
37 ntroduces several detailed reviews about the ubiquitin system and autophagy.
38 ight some emerging relationships between the ubiquitin system and disease, and discuss current and fu
39 lving membrane proteins, including the split ubiquitin system and fluorescence-based technologies for
40 ce for the emerging relationship between the ubiquitin system and human disease.
41 ms of signal transduction, especially in the ubiquitin system and in chromatin.
42     We conclude that human cells utilize the ubiquitin system and NDP52 to activate autophagy against
43 ion of CSIT2 inhibits the possible damage to ubiquitin system and protein translation, which allows m
44      This review presents information on the ubiquitin system and regulation of NF-kappaB by ubiquiti
45      This review presents information on the ubiquitin system and regulation of NF-kB by ubiquitinati
46 orts targeting the various components of the ubiquitin system and studying the role of DUBs in health
47 cular complementation assays (i.e. the split ubiquitin system and the split luciferase system).
48 s both the high substrate specificity of the ubiquitin system and the variety of regulatory mechanism
49  studies on how seed size is affected by the ubiquitin system, and discuss how the ubiquitin system a
50 ide an additional layer of regulation in the ubiquitin system, and distinct conformations observed in
51 ents of the cell cycle, apoptotic machinery, ubiquitin system, and DNA damage response pathways.
52                            Substrates of the ubiquitin system are degraded by the 26 S proteasome, a
53 rol cellular behavior and alterations in the ubiquitin system are linked to many diseases.
54 r data suggest widespread involvement of the ubiquitin system at multiple stages of the Met activatio
55  identify Cuz1/Ynl155w as a component of the ubiquitin system, capable of interacting with both the p
56 ations in genes coding for components of the ubiquitin system cause immune dysregulation.
57      In a single vascular plant species, the ubiquitin system consists of thousands of different prot
58         Various destabilizing factors of the ubiquitin system contribute to the synchrony and unidire
59                   Protein degradation by the ubiquitin system controls the intracellular concentratio
60                           Thus, galectin and ubiquitin systems converge to activate AMPK and autophag
61                                          The ubiquitin system for protein degradation, which has rece
62                             The power of the ubiquitin system for therapeutic benefit blossomed with
63              Our study suggests that altered ubiquitin system function in the CNS contributes to the
64  advanced our understanding of the canonical ubiquitin system, further study of noncanonical ubiquiti
65 ied multiple causal variants in each of four ubiquitin system genes whose products process (NTA1), re
66                                          The ubiquitin system has become synonymous with the modifica
67                                          The ubiquitin system has been identified as the nonlysosomal
68 Trojan horses" integrate into the eukaryotic ubiquitin system has remained a mystery.
69 overy programs that target components of the ubiquitin system have lagged behind.
70 mall molecule degraders that act through the ubiquitin system have spurred efforts to extend this tec
71             I provide an introduction to the ubiquitin system, highlight some emerging relationships
72 egans have identified multiple roles for the ubiquitin system in early development, where ubiquitin-d
73                        The importance of the ubiquitin system in health and disease has been widely r
74  ndc10-2 function and suggest a role for the ubiquitin system in kinetochore function.
75 n signals similar to those recognized by the ubiquitin system in misfolded proteins.
76           Our data reveal a new role for the ubiquitin system in mitotic spindle regulation and under
77                  These results implicate the ubiquitin system in poxviral virulence.
78 ate the requirement for an active proteasome/ubiquitin system in release and maturation of infectious
79 BL1 system shares many similarities with the ubiquitin system in structures and in conjugation with e
80 findings, this study suggests a role for the ubiquitin system in the destabilization and rupture of c
81                  These results implicate the ubiquitin system in the regulation of ndc10-2 function a
82  a previous report on the involvement of the ubiquitin system in the tobacco HR [2], and validates an
83 our current understanding of the role of the ubiquitin system in various human diseases ranging from
84 ding of the disruptions to components of the ubiquitin system, in particular E3 ligases and deubiquit
85 s that are associated with components of the ubiquitin system, including ubiquitin, ubiquitin-like pr
86                   A protein substrate of the ubiquitin system is conjugated to ubiquitin through the
87                               The eukaryotic ubiquitin system is conserved in archaea and involved in
88                                          The ubiquitin system is critical for proper neuronal cell st
89                                  Because the ubiquitin system is known to play an important role in r
90 ignaling pathways and how alterations in the ubiquitin system lead to the development of distinct hum
91 opment and regeneration are degraded via the ubiquitin system, little is known about the mechanisms a
92                   Interference with the host ubiquitin system may therefore be a common theme among e
93                                          The ubiquitin system of protein modification has emerged as
94  an important enzyme in the highly conserved ubiquitin system of proteolysis.
95               Despite lacking a conventional ubiquitin system of their own, many bacterial ubiquitin
96 sive neighborhoods with either a prokaryotic ubiquitin-system or a HORMA domain-PCH2-like AAA+ ATPase
97                            In regards to the ubiquitin system, our study may have implications on the
98 al proteins associated with cytoskeletal and ubiquitin system proteins exhibited a more complex evolu
99 s of pathogen-derived proteins on plant host ubiquitin system proteins.
100                                          The ubiquitin system regulates essential cellular processes
101                                          The ubiquitin system regulates the DNA damage response (DDR)
102                                          The ubiquitin system represents an attractive pharmacologica
103 underappreciated, bringing us to an epoch in ubiquitin system research.
104     Current drug discovery activities in the ubiquitin system seek to (i) expand the development of n
105 reover, Helarchaeota viruses may hijack host ubiquitin systems similar to eukaryotic viruses.
106                                          The ubiquitin system targets many cellular proteins.
107 ay in this pipeline, the drugs targeting the ubiquitin system that have been developed, and new appro
108 and MDP3/PAN1, implicate interactions of the ubiquitin system, the actin cytoskeleton and protein syn
109                   Although bacteria lack the ubiquitin system, they also have N-degron pathways.
110 er report has shown that inactivation of the ubiquitin system through blocking E1 (ubiquitin-activati
111  Thus, HD is linked to global changes in the ubiquitin system to a much greater extent than previousl
112 ffectors have evolved to manipulate the host ubiquitin system to alter host cell physiology or the lo
113 e UBA domains functionally interact with the ubiquitin system to control Pds1p degradation in respons
114  NS2 important for interaction with the host ubiquitin system to degrade STAT2 during infection.
115 und that trametinib activates the proteasome-ubiquitin system to downregulate Id1 in KRAS-mutant LUAD
116                Many pathogens manipulate the ubiquitin system to evade these defenses.
117 aspect in the manipulation of the eukaryotic ubiquitin system to facilitate bacterial replication and
118 ependent host responses, or even exploit the ubiquitin system to their own advantage.
119 t immune system; how plants use ethylene and ubiquitin systems to control growth and development; and
120 brane protein two-hybrid approach, the split-ubiquitin system, to address two aspects of the enzyme c
121 rated that a multifunctional molecule of the ubiquitin system ubiquitin C-terminal hydrolase L1 (UCH-
122     While ubc4Delta and other alterations of ubiquitin system used in this work cause slight inductio
123 spite the extensive efforts in targeting the ubiquitin system, very few E2 binders have currently bee
124                 Thus, HDAC6 is linked to the ubiquitin system via ubiquitin conjugation, polyubiquiti
125                         The discovery of the ubiquitin system was awarded with the Nobel Prize in Che
126 iquitylases (DUBs) are key regulators of the ubiquitin system which cleave ubiquitin moieties from pr
127   DNA replication is highly regulated by the ubiquitin system, which plays key roles upon stress.
128 ective we provide a short description of the ubiquitin system, with specific emphasis given to its ro

 
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