ライフサイエンスコーパス: ubiquitin-dependent

1 ytic activity of 26 S proteasome is ATP- and ubiquitin-dependent.

2 tilizing both autophagic-lysosomal (ALD) and ubiquitin-dependent 26S proteasomal (UPD) degradation pa

3 They are degraded by the ubiquitin-dependent 26S proteasome.

4 cytosolic RING domain, and proceeds via the ubiquitin-dependent 26S proteosome pathway.

5 dispensable for chromatin ubiquitylation and ubiquitin-dependent accumulation of repair factors at DS

6 embrane recruitment of Otub1, which inhibits ubiquitin-dependent activation of AKT, a kinase that is

7 Further studies indicate that ubiquitin-dependent activation of ataxin-3 at Lys-117 is

8 Thus, ubiquitin-dependent and -independent pathways robustly c

9 sentation, whereas depleting RPL28 increases ubiquitin-dependent and -independent peptide presentatio

10 The potential cross-talk between the ubiquitin-dependent and -independent protein quality con

11 tes in vitro, it inhibits the degradation of ubiquitin-dependent and -independent substrates in vivo.

12 when expressed at the C-terminal regions of ubiquitin-dependent and -independent substrates of the 2

13 mportance of vesicular trafficking pathways, ubiquitin-dependent and autophagy-related processes, and

14 a family of trafficking adaptors, stimulate ubiquitin-dependent and clathrin-mediated endocytosis by

15 degradation of Polbeta is regulated by both ubiquitin-dependent and ubiquitin-independent processes

16 level of SRC-3 is tightly regulated by both ubiquitin-dependent and ubiquitin-independent proteasoma

17 s by coordinate enzymatic inhibition of both ubiquitin-dependent and ubiquitin-independent proteolyti

18 he capsid cores of retroviruses and activate ubiquitin-dependent antiviral responses upon capsid reco

19 UBs) suggests they remove ubiquitin to evade ubiquitin-dependent antiviral responses; however, this h

20 ependent ubiquitination of ELKS leads to the ubiquitin-dependent assembly of TAK1/TAB2/3 and NEMO/IKK

21 ition of Valosin-Containing Protein (VCP), a ubiquitin-dependent ATPase whose human homolog is linked

22 obacterium tuberculosis infection stimulates ubiquitin-dependent autophagy and inflammatory cytokine

23 BCR ubiquitination, trafficking to MIIC, and ubiquitin-dependent BCR-mediated antigen processing and

24 on but still able to down regulate B7.2 in a ubiquitin-dependent but endocytosis-independent manner.

25 ion can be broadly grouped into two classes, ubiquitin-dependent cargo recognition versus ubiquitin-i

26 lias p97 or VCP) is a key player in multiple ubiquitin-dependent cell signaling, degradation, and qua

27 creens for identification of antagonizers of ubiquitin-dependent cellular responses.

28 Cdc48/p97 is an evolutionary conserved ubiquitin-dependent chaperone involved in a broad array

29 ators is also required for execution of this ubiquitin-dependent chromatin response.

30 assembly regions, demonstrating that Gag has ubiquitin-dependent, cis-acting late domain activities l

31 revealed that infection supernatants elicit ubiquitin-dependent class II downregulation and degradat

32 gest that DnaJA1 triages all tau species for ubiquitin-dependent clearance mechanisms.

33 y which a specific E3 ligase is required for ubiquitin-dependent control of pAKT dynamics in a ligand

34 TOR-independent linkage between PTEN and the ubiquitin-dependent control of protein stability.

35 Ca(2+), which leads to CSF inactivation and ubiquitin-dependent cyclin destruction through the anaph

36 SL2, a novel E3 ligase for p53 that promotes ubiquitin-dependent cytoplasmic p53 localization.

37 atrix proteins might exit the peroxisome for ubiquitin-dependent cytosolic degradation.

38 a histone H2A DUB which negatively regulates ubiquitin-dependent DDR signaling.

39 ylation of a terminal phosphodegron promotes ubiquitin-dependent degradation (the phosphorylation of

40 erminal domain of PTEN, thereby resulting in ubiquitin-dependent degradation and diminished abundance

41 ally involved in regulating WRN function via ubiquitin-dependent degradation and reveal an unexpected

42 ated to the cytosol for proteasome-mediated, ubiquitin-dependent degradation by a process termed endo

43 S1 may allow the translocated toxin to avoid ubiquitin-dependent degradation by the 26S proteasome, w

44 of the 19S regulatory particle essential for ubiquitin-dependent degradation by the proteasome.

45 ed for genomic stability and is targeted for ubiquitin-dependent degradation in a cell cycle-dependen

46 data suggesting that alpha4 is regulated by ubiquitin-dependent degradation mediated by MID1.

47 coproteins, including c-Myc, is regulated by ubiquitin-dependent degradation mediated by the SCF(Fbw7

48 studies have shown that AKR1B10 mediates the ubiquitin-dependent degradation of acetyl-CoA carboxylas

49 ls, we determined that USP28 antagonizes the ubiquitin-dependent degradation of c-MYC, a known USP28

50 KL001 prevented ubiquitin-dependent degradation of CRY, resulting in len

51 We also show that aspirin causes rapid, ubiquitin-dependent degradation of cyclin D1, a known p3

52 n of protein expression both through altered ubiquitin-dependent degradation of cytosolic proteins an

53 asitas B lymphoma protein (Cbl) controls the ubiquitin-dependent degradation of EGF receptor (EGFR),

54 mal degradation of unstructured proteins and ubiquitin-dependent degradation of folded proteins when

55 ack regulation of insulin signaling involves ubiquitin-dependent degradation of insulin receptor subs

56 ty of surface pMHC-II in DCs is regulated by ubiquitin-dependent degradation of internalized pMHC-II.

57 CHIP in regulating HIV-1 replication through ubiquitin-dependent degradation of its regulatory protei

58 (JA) activates gene expression by promoting ubiquitin-dependent degradation of jasmonate ZIM domain

59 he F-box protein COI1 triggers the SCF(COI1)/ubiquitin-dependent degradation of JASMONATE ZIM-DOMAIN

60 The suppression is achieved through the ubiquitin-dependent degradation of Mitofusin, which itse

61 TRAF2 and TRAF3 in this aspect is to mediate ubiquitin-dependent degradation of nuclear factor-kappaB

62 cell lines, ionizing radiation (IR) induces ubiquitin-dependent degradation of p21(Cip1).

63 ion of these lysine residues is required for ubiquitin-dependent degradation of p53.

64 re, we show that Upf complex facilitates the ubiquitin-dependent degradation of products derived from

65 fers to the use of small molecules to induce ubiquitin-dependent degradation of proteins.

66 We found that the ubiquitin-dependent degradation of Rpn4 can be mediated

67 Here we studied the mechanism underlying ubiquitin-dependent degradation of Rpn4, a transcription

68 identified the mub1Delta mutant defective in ubiquitin-dependent degradation of Rpn4.

69 Here we show that both ubiquitin-dependent degradation of Stp1 and Stp2 and the

70 uggesting that Rfp/Slx8 proteins may promote ubiquitin-dependent degradation of SUMOylated targets.

71 in inhibiting the production of TGF-beta1 by ubiquitin-dependent degradation of Syk.

72 rate that CHIP is a primary component in the ubiquitin-dependent degradation of tau.

73 To promote ubiquitin-dependent degradation of the folded domains of

74 and animal development, guided by selective ubiquitin-dependent degradation of the sperm-borne mitoc

75 k1-cyclin B1 and becomes unleashed only upon ubiquitin-dependent degradation of these regulators.

76 lin) is an E3 ubiquitin ligase that promotes ubiquitin-dependent degradation of Thr286-phosphorylated

77 feeding by promoting the phosphorylation and ubiquitin-dependent degradation of TORC2.

78 histidine-rich domain that was essential for ubiquitin-dependent degradation of ZIP4 and protection a

79 tine-insensitive 1 (COI1) to, and subsequent ubiquitin-dependent degradation of, jasmonate ZIM domain

80 alpha-synuclein aggregation by blocking its ubiquitin-dependent degradation pathways and promoting i

81 We provide evidence that two distinct ubiquitin-dependent degradation pathways for beta-cateni

82 e 26S proteasome recognizes a vast number of ubiquitin-dependent degradation signals linked to variou

83 reased hypothalamic SF-1 levels by promoting ubiquitin-dependent degradation, and sumoylation was req

84 ting cell cycle and cell growth proteins for ubiquitin-dependent degradation, but the diverse develop

85 The stability of p53 is tightly regulated by ubiquitin-dependent degradation, driven mainly by the ub

86 ased the ability of Keap1 to target Nrf2 for ubiquitin-dependent degradation, resulting in stabilizat

87 specific cell cycle regulatory proteins for ubiquitin-dependent degradation, thereby controlling cel

88 OR1-bound, transcriptionally-inactive AR for ubiquitin-dependent degradation, thereby promoting expre

89 lso targets additional signaling factors for ubiquitin-dependent degradation, thereby regulating impo

90 argeting NF-kappaB-inducing kinase (NIK) for ubiquitin-dependent degradation, thus preventing process

91 ression of 19S RP subunits, which facilitate ubiquitin-dependent degradation, were decreased in the c

92 pSPKLpS(1365) of topoIIalpha, leading to its ubiquitin-dependent degradation.

93 t from Annexin 2 and making it accessible to ubiquitin-dependent degradation.

94 oa10 recognition, protecting Hcn1/Cdc26 from ubiquitin-dependent degradation.

95 d promotes its stabilization by antagonizing ubiquitin-dependent degradation.

96 ts nuclear localization in beta cells or its ubiquitin-dependent degradation.

97 anges may reveal or mask the signals for the ubiquitin-dependent degradation.

98 SUMOylation can serve as a direct signal for ubiquitin-dependent degradation.

99 obstructed kidney is mediated by an enhanced ubiquitin-dependent degradation.

100 nfolding, which may provide a signal for the ubiquitin-dependent degradation.

101 p53 protein in a cell is normally limited by ubiquitin-dependent degradation.

102 mplexes that target substrate protein(s) for ubiquitin-dependent degradation.

103 lated by posttranslational modifications and ubiquitin-dependent degradation.

104 ast in response to cellular requirements for ubiquitin-dependent degradation.

105 ngly stabilizes PGC-1alpha by inhibiting its ubiquitin-dependent degradation.

106 d at the metaphase-to-anaphase transition by ubiquitin-dependent degradation.

107 Whereas ubiquitin-dependent degrons have been characterized in s

108 ), a sophisticated process that mediates the ubiquitin-dependent delivery of substrates to the 26S pr

109 Accumulation of this factor is limited by ubiquitin-dependent destabilization, apparently mediated

110 g proteins such as securin and cyclin B1 for ubiquitin-dependent destruction by the proteasome.

111 ticulum (ER) are dislocated and targeted for ubiquitin-dependent destruction by the proteasome.

112 The Golgi apparatus undergoes a ubiquitin-dependent disassembly and reassembly process d

113 been shown to be involved in regulating the ubiquitin-dependent down-regulation of activated cell su

114 in EOMG implies disease mechanisms involving ubiquitin-dependent dysregulation of NF-kappaB signaling

115 Although their role in ubiquitin-dependent endocytosis and degradation of cell-

116 otch signaling pathway, participating in the ubiquitin-dependent endocytosis of Delta.

117 The HRD pathway is a conserved route of ubiquitin-dependent, endoplasmic reticulum (ER)-associat

118 for Galphas as an integral component of the ubiquitin-dependent endosomal sorting machinery and high

119 rs, not viral proteins, appears critical for ubiquitin-dependent enveloped viral particle release.

120 of late endosomes (multivesicular bodies), a ubiquitin-dependent event that requires the coordinated

121 Following binding, poorly understood, ubiquitin-dependent events lead to the disassembly of th

122 However, how ubiquitin-dependent FAAP20 degradation is modulated to f

123 This ubiquitin-dependent folding system also controls the pro

124 t highlight the diversity and specificity of ubiquitin dependent functions in immune cells.

125 facilitates Crn7 targeting to TGN through a ubiquitin-dependent interaction with Eps15.

126 Interestingly, CYLD targets a ubiquitin-dependent kinase, transforming growth factor-b

127 By investigating ubiquitin-dependent lysosomal degradation of the interfe

128 a dual mechanism that concurrently promotes ubiquitin-dependent lysosomal sorting of the receptor an

129 1 destruction and is degraded in a Plk1- and ubiquitin-dependent manner in early mitosis.

130 GLI3 processing is triggered in an ubiquitin-dependent manner via SCF(betaTrCP1) complex; h

131 duces relocalization of the IKK complex in a ubiquitin-dependent manner, and dynamic changes in the s

132 zing to different cellular compartments in a ubiquitin-dependent manner.

133 olled by IRT1 non-iron metal substrates in a ubiquitin-dependent manner.

134 K293 cells, was transported to exosomes in a ubiquitin-dependent manner.

135 In this study, we identified an ubiquitin-dependent mechanism by which BRCA1 inhibits tr

136 h BAF155, suggesting that in addition to the ubiquitin-dependent mechanism of BAF57 degradation, ther

137 Here we identify a ubiquitin-dependent mechanism that integrates gene expre

138 is targeted for lysosomal degradation via a ubiquitin-dependent mechanism that involves the endosoma

139 ubiquitin-regulated and that Rip2 employs a ubiquitin-dependent mechanism to achieve NF-kappaB activ

140 within MVBs occurs via a well-characterized ubiquitin-dependent mechanism, which is blocked by acute

141 t alphakap promoted AChRalpha stability by a ubiquitin-dependent mechanism.

142 ulates the NF-kappaB signaling pathway by an ubiquitin-dependent mechanism.

143 These results indicate that distinct ubiquitin-dependent mechanisms are employed for IKK acti

144 Ubiquitin-dependent mechanisms have emerged as essential

145 this system is impaired by mutation of Vms1, ubiquitin-dependent mitochondrial protein degradation, m

146 Using a ubiquitin-dependent mitophagy inducer, the lactone iverm

147 e report here that LLO is a substrate of the ubiquitin-dependent N-end rule pathway, which recognizes

148 that can act as a degradation signal for the ubiquitin-dependent N-end rule pathway.

149 Ubiquitin-dependent NCOA4 turnover is promoted by excess

150 aining vesicles is transient and followed by ubiquitin-dependent NDP52 recruitment.

151 urther show that CYLD negatively regulates a ubiquitin-dependent NF-kappaB activator, RIP1.

152 esults suggest TIEG and Itch contribute to a ubiquitin-dependent nonproteolytic pathway that regulate

153 sphorylates serine-85 of NEMO to promote its ubiquitin-dependent nuclear export.

154 iological conditions is controlled by either ubiquitin-dependent or receptor-dependent mechanisms.

155 dily remove both recognition subunits by the ubiquitin-dependent p97/VCP/Cdc48 segregase complex, lea

156 BCR complexes to MVB-like MIIC occurs via an ubiquitin-dependent pathway and that ubiquitination of A

157 Inhibition of the ubiquitin-dependent pathway by the chemical proteasome i

158 Here, we define an atypical ubiquitin-dependent pathway for p38 activation used by P

159 wn proteins targeted for degradation by this ubiquitin-dependent pathway in plants.

160 , our work reveals a previously unrecognized ubiquitin-dependent pathway induced specifically to repa

161 4/NOT in the regulation of H3K4me3 through a ubiquitin-dependent pathway that likely involves the pro

162 which limits channel availability through a ubiquitin-dependent pathway.

163 g of Tau degradation toward a less efficient ubiquitin-dependent pathway.

164 and regulates the stability of Polbeta via a ubiquitin-dependent pathway.

165 e for distinct, post-translationally active, ubiquitin-dependent pathways capable of controlling the

166 Here, we determined that ubiquitin-dependent pathways regulate neuromuscular path

167 entable pathway related, and in genes in the ubiquitin-dependent pathways such as USP9X.

168 enzymes (DUbs) play important roles in many ubiquitin-dependent pathways, yet how DUbs themselves ar

169 lly activate both degradative and regulatory ubiquitin-dependent pathways.

170 C-terminus alpha6 helix through two parallel ubiquitin-dependent pathways: the ESCRT-I-ESCRT-II-Vps20

171 Depleting RPL6 decreases ubiquitin-dependent peptide presentation, whereas deplet

172 roduction of autophagosomes by a reversible, ubiquitin-dependent process selective for ATG16L1.

173 thus promoting the degradation of Bub1 in a ubiquitin-dependent process.

174 Ubiquitin-dependent processes are critical for propagati

175 Since ubiquitin-dependent processes are usually mediated by ce

176 ions is challenging the current dogma on how ubiquitin-dependent processes culminate in the activatio

177 ing enzyme catalyzes the initial step in all ubiquitin-dependent processes.

178 achieve regulatory roles in many aspects of ubiquitin-dependent processes.

179 ubiquitination and play an important role in ubiquitin-dependent processes.

180 al machinery that are directly controlled by ubiquitin-dependent processes.

181 it is not clear how the 26S proteasome, the ubiquitin-dependent protease that is only capable of deg

182 Here, we show that Ddi1 is a ubiquitin-dependent protease, which cleaves substrate pr

183 degradation has indicated that CYPs 3A incur ubiquitin-dependent proteasomal degradation (UPD) in an

184 that incurs endoplasmic reticulum-associated ubiquitin-dependent proteasomal degradation (UPD).

185 RIB2 and C/EBPalpha p42 for the K48-specific ubiquitin-dependent proteasomal degradation of C/EBPalph

186 proteins implicated in the regulation of the ubiquitin-dependent proteasomal degradation of cellular

187 ition of Hsp90 with geldanamycin resulted in ubiquitin-dependent proteasomal degradation of KDM4B, bu

188 rminants of substrate specificity within the ubiquitin-dependent proteasomal degradation of proteins,

189 hysical complex with SnoN and stimulates the ubiquitin-dependent proteasomal degradation of SnoN in n

190 theme is that viperin appears to facilitate ubiquitin-dependent proteasomal degradation of some of t

191 es in response to inflammation, triggers the ubiquitin-dependent proteasomal degradation of the cytoc

192 ptional repression of AR by facilitating the ubiquitin-dependent proteasomal degradation of the trans

193 ndance of PTEN was reversed by inhibition of ubiquitin-dependent proteasomal degradation.

194 hed that Myc levels are in part regulated by ubiquitin-dependent proteasomal degradation.

195 at orthologs are phosphorylated during their ubiquitin-dependent proteasomal degradation.

196 r stabilizing beta-catenin by inhibiting its ubiquitin-dependent proteasomal degradation.

197 air proteins to the CRL4-DCAF1 E3 ligase for ubiquitin-dependent proteasomal degradation.

198 h stabilizes RUNX2 by diverting it away from ubiquitin-dependent proteasomal degradation.

199 ligase ITCH, which bound and target WBP2 for ubiquitin-dependent proteasomal degradation.

200 he tumor suppressor LATS exhibiting enhanced ubiquitin-dependent proteasomal degradation.

201 of cIAP1, an E3 ligase that targets CAS for ubiquitin-dependent proteasomal degradation.

202 n from p53, which induces HDAC3 cleavage and ubiquitin-dependent proteasomal degradation.

203 eps: substrate recognition, dislocation, and ubiquitin-dependent proteasomal destruction.

204 retards the degradation of hTDO through the ubiquitin-dependent proteasomal pathway.

205 Both classes of genes encode ubiquitin-dependent proteasome adapters, which recruit d

206 tion with Bcl-6 and protection of Bcl-6 from ubiquitin-dependent proteasome degradation.

207 tumors, induces Ski degradation through the ubiquitin-dependent proteasome in malignant human cancer

208 sfolded proteins for degradation through the ubiquitin-dependent proteasome pathway.

209 G132, indicating that it is degraded via the ubiquitin-dependent proteasome pathway.

210 lity of E2 that is normally degraded via the ubiquitin-dependent proteasome pathway.

211 otein whose levels are regulated through the ubiquitin-dependent proteasome pathway.

212 in that regulates the degradation of several ubiquitin-dependent proteasome substrates.

213 ndoplasmic reticulum (ER) are cleared by the ubiquitin-dependent proteasome system in the cytosol, a

214 g E3 ubiquitin ligases target substrates for ubiquitin-dependent, proteasome-mediated degradation and

215 important, evolutionarily conserved roles in ubiquitin dependent protein degradation.

216 redundancy among cellular DUBs that restrict ubiquitin-dependent protein assembly at DSBs.

217 evelopment, ABA-mediated signalling pathway, ubiquitin-dependent protein catabolic process, ion trans

218 In contrast, proteasome-mediated ubiquitin-dependent protein catabolic process, negative

219 Forty genes in ubiquitin-dependent protein catabolism, protein biosynth

220 on domain-binding protein 1 (JAB1) regulates ubiquitin-dependent protein degradation by deneddylation

221 ubiquitin system in early development, where ubiquitin-dependent protein degradation governs such div

222 TP-dependent protease complexes that execute ubiquitin-dependent protein degradation in eukaryotes, c

223 Ubiquitin-dependent protein degradation is essential for

224 Although ubiquitin-dependent protein degradation is impaired in c

225 Ubiquitin-dependent protein degradation is used as a reg

226 ase in protein synthesis, but a reduction in ubiquitin-dependent protein degradation pathways was als

227 reported that modification at Lys-6 inhibits ubiquitin-dependent protein degradation, a failure of th

228 Ubiquitin-dependent protein degradation, hydrolysis of s

229 atory particle that normally participates in ubiquitin-dependent protein degradation, is required for

230 iquitin ligase complex, which is involved in ubiquitin-dependent protein degradation.

231 phorylation events and distinct mediators of ubiquitin-dependent protein degradation.

232 his review is the finding of a mitochondrial ubiquitin-dependent protein quality control and that thi

233 presents an important point of regulation in ubiquitin-dependent protein quality control.

234 rd loop connecting oncogenic translation and ubiquitin-dependent protein stabilization in melanoma.

235 ns, which suggest that ataxin-3 functions in ubiquitin-dependent protein surveillance.

236 plexes that contribute to about one-fifth of ubiquitin-dependent protein turnover in cells.

237 esponse to DNA damage, iron ion homeostasis, ubiquitin dependent proteolysis, autophagy and regulatio

238 the data suggest that Int6 depletion blocks ubiquitin-dependent proteolysis by decreasing both ubiqu

239 Ubiquitin-dependent proteolysis can initiate at ribosome

240 ns with expanded polyglutamine tracts impair ubiquitin-dependent proteolysis due to their propensity

241 s also demonstrate that KLF4 is targeted for ubiquitin-dependent proteolysis during cell cycle progre

242 These mutants cannot sustain ubiquitin-dependent proteolysis even though neither moti

243 g hypoxia-inducible factor-alpha subunits to ubiquitin-dependent proteolysis has been well documented

244 Ubiquitin-dependent proteolysis is an important mechanis

245 to the nucleus in G(1) phase, but undergoes ubiquitin-dependent proteolysis later in cell cycle.

246 Ubiquitin-dependent proteolysis of cyclin B and securin

247 Ubiquitin-dependent proteolysis of cyclin D1 is associat

248 multiprotein E3 ubiquitin ligase involved in ubiquitin-dependent proteolysis of key cell cycle regula

249 , also known as the cyclosome) regulates the ubiquitin-dependent proteolysis of specific cell-cycle p

250 By triggering the appropriately timed, ubiquitin-dependent proteolysis of the mitotic regulator

251 -based E3 ubiquitin ligase that promotes the ubiquitin-dependent proteolysis of various substrates im

252 Ubiquitin-dependent proteolysis plays an important role

253 ntial susceptibility of the catalytic LCs to ubiquitin-dependent proteolysis therefore might explain

254 As such, TRF1 levels are regulated by ubiquitin-dependent proteolysis via an SCF E3 ligase whe

255 etwork of proteins that function together in ubiquitin-dependent proteolysis, and the UBL method offe

256 n the established role of the RUB pathway in ubiquitin-dependent proteolysis, these data suggest that

257 Many proteins are regulated by ubiquitin-dependent proteolysis.

258 d negatively regulates Ira2 by promoting its ubiquitin-dependent proteolysis.

259 s an E3 RING domain and targets proteins for ubiquitin-dependent proteolysis.

260 h F-box-binding protein beta-TrCP, undergoes ubiquitin-dependent proteolysis.

261 criptional activity and targets ER alpha for ubiquitin-dependent proteolysis.

262 dulate multiple biological processes through ubiquitin-dependent proteolysis.

263 rogression and postmitotic processes through ubiquitin-dependent proteolysis.

264 Substrates of a ubiquitin-dependent proteolytic system called the N-end

265 rate for the N-end rule pathway, which is an ubiquitin-dependent proteolytic system in which the iden

266 t proteins for destruction by exploiting the ubiquitin-dependent proteolytic system of eukaryotic cel

267 e is a part of the Arg/N-end rule pathway, a ubiquitin-dependent proteolytic system.

268 TCDD also increased acetylation and ubiquitin-dependent proteosomal degradation of the perox

269 rols cell surface Cav1.3 levels by promoting ubiquitin-dependent proteosomal degradation.

270 followed by its subsequent degradation by an ubiquitin-dependent quality control pathway called RADAR

271 We conclude that ubiquitin-dependent regulation of translation is an impo

272 lded ER-resident proteins is well described, ubiquitin-dependent regulation of translational reprogra

273 rs is a highly dynamic process that involves ubiquitin-dependent regulation.

274 f SAG-CUL1-FBXW7 E3 ligase and establishes a ubiquitin-dependent regulatory mechanism for the NF1-RAS

275 the plant includes protein interactions and ubiquitin-dependent repressor degradation.

276 stress response is therefore built around a ubiquitin-dependent rheostat that tunes mitochondrial ac

277 We conclude that the ubiquitin-dependent sculpting of the chromosomal distrib

278 l conditions, might be sufficient to trigger ubiquitin-dependent sequestration of partially misfolded

279 ism for the integrated regulation of diverse ubiquitin-dependent signaling pathways through E2 phosph

280 ntly been developed to dissect mechanisms of ubiquitin-dependent signaling, thereby revealing the cri

281 biquitin to target proteins thereby enabling ubiquitin-dependent signaling.

282 versatility, specificity, and efficiency of ubiquitin-dependent signaling.

283 er, which is contrary to the current idea of ubiquitin-dependent sorting of proteins to exosomes.

284 vealed by observation of UbcH7 approximately ubiquitin-dependent substrate inhibition of chain format

285 Degradation of a ubiquitin-dependent substrate was restored by the rpt2(E

286 ochondrial division is regulated by a MARCH5 ubiquitin-dependent switch.

287 The N-end rule pathway is a ubiquitin-dependent system where E3 ligases called N-rec

288 icle (SV) proteins is thought to involve the ubiquitin-dependent tagging and degradation through endo

289 Degradation of p27(Kip1) is mediated by ubiquitin-dependent targeting of p27(Kip1) by SCF -Skp2.

290 al protein stability, possibly by preventing ubiquitin-dependent targeting of viral proteins for dest

291 ially lower processivity of degradation than ubiquitin-dependent targeting.

292 ate (HRS) was characterized as necessary for ubiquitin-dependent TLR9 targeting to the endolysosome.

293 activity is dependent upon NEDD8, Cif blocks ubiquitin dependent trafficking of Perforin-2 and thus,

294 critical induction events involve changes in ubiquitin-dependent trafficking of MHC-II and CD86 by th

295 Although ubiquitin-dependent trafficking of MHC-II has been well

296 novel E3 ligase that specifically regulates ubiquitin-dependent trafficking of pAKT in insulin-like

297 at is reminiscent of, yet distinct from, the ubiquitin-dependent transactivation of the oncoprotein M

298 etylation in the presence of T3 and enhances ubiquitin-dependent TRbeta1 turnover; a common response

299 cellular machinery, composed of the p97/VCP ubiquitin-dependent unfoldase/segregase and the Ataxin 3

300 nhance zinc secretion and then by activating ubiquitin-dependent ZnT2 degradation.