ライフサイエンスコーパス: ultimate

1 ted peptide sequences resulting from Nano LC Ultimate 3000 Series System tandem Q Exactive(TM) Hybrid

2 help to address this knowledge gap with the ultimate aim of improving malaria treatments.

3 ght on a detailed structural level, with the ultimate aim to rationally design molecules to maximise

4 inely "undetectable" transmission remain the ultimate aim.

5 (PubMed), business journals (Business Source Ultimate), and news media (Lexis Nexis) for articles abo

6 Lithium metal is considered the ultimate anode material for future rechargeable batterie

7 theoretical specific capacity, making it the ultimate anode material for rechargeable batteries.

8 Lithium metal, the ultimate anode with the highest specific capacity, also

9 l in the exploration of biology and in their ultimate application to medicine.

10 c efficiency of enzyme cascade reaction with ultimate applications in bioanalysis and clinical diagno

11 The development and ultimate approval of tecovirimat for the antiviral treat

12 early and late intermediates and direct the ultimate assembly path to late intermediates where assem

13 derived suppressor cells (MDSC) might be the ultimate barrier to break down tumor defenses and recove

14 recipients of the intervention, whereas the ultimate beneficiaries were pregnant women attending ANC

15 vary and contributes to drug deposition and ultimate bioavailability in the lung.

16 This study thus shows that the ultimate bottlenecks for bimolecular photoredox processe

17 ted that systems would approach U.S. DRIVE's ultimate capacity targets but fall short of cost targets

18 companied by metastasis and is currently the ultimate cause of prostate cancer-associated deaths in m

19 Photoreceptor cell death is the ultimate cause of vision loss in many retinal disorders,

20 raise new questions about the proximate and ultimate causes of selective transmission across generat

21 We also discuss proximate and ultimate causes of size variation and how variation in w

22 However, the ultimate cellular processes governing the adaptation of

23 The ultimate challenge is to decipher the comprehensive and

24 The ultimate challenge will be to enable these advances in l

25 ts of mineral-interacting functions poses an ultimate challenge.

26 assemblies of complex genomes is one of the ultimate challenges in genomics.

27 Metal-organic frameworks represent the ultimate chemical platform on which to develop a new gen

28 ination and Orton rearrangement; and (c) the ultimate chemical transformations (C-chlorination or ami

29 tallic element, has long been considered the ultimate choice as a battery anode for mobile, as well a

30 The World Health Assembly's ultimate choice will lead an organisation facing dauntin

31 sion resistance of Mg and retained 86-90% of ultimate compressive strength after in vitro immersion i

32 ral neck cortical bone's elastic modulus and ultimate compressive strength at the millimetre length s

33 ngth was 1165 MPa with ductility of ~18% and ultimate compressive strength was 1863 MPa with a total

34 The ultimate consequence of quantum many-body physics is tha

35 itous hard landscapes (and the corresponding ultimate constraint on evolution) are in nature becomes

36 systematic development of ANN models allowed ultimate construction of a single in silico model which

37 ctates carrier lifetimes, energetics and the ultimate conversion yields.

38 The scope, magnitude, footprint and ultimate cumulative impacts of human activities can thre

39 e of an epidermal cell from its birth to its ultimate death, and detail how this journey is necessary

40 ) domain, TTP promotes the deadenylation and ultimate decay of target transcripts.

41 ATP and its ultimate degradation product adenosine are potent extrac

42 mentation leading to dialkylpyridines as the ultimate degradation products.

43 zed beta1 integrin to late endosomes and its ultimate degradation.

44 each cell is fundamentally important for the ultimate delineation of organ formation and function.

45 time scales in catchment soils prior to its ultimate deposition.

46 Here we describe the rationale and ultimate design of a comprehensive biomarker plan to ena

47 e-atom catalysts are often considered as the ultimate design principle for supported catalysts, due t

48 o these guidelines to be voluntary, with the ultimate determination regarding their application to be

49 Peptide design alters the ultimate device form factor, ranging from circulating na

50 The ultimate diagnoses were NAD = 43 (49%), CD = 17 (19%), I

51 Female gender was associated with an ultimate diagnosis of IBS (OR 5, p < 0.02).

52 6%) did not require hospitalization based on ultimate diagnosis, and 48 (92.3%) received unnecessary

53 Patients were grouped based on ultimate diagnosis: Crohn's disease (CD), Irritable bowe

54 owing to their atomic thinness enabling the ultimate dimensional scaling.

55 ogenian and were a prerequisite, but not the ultimate driver for the algal rise.

56 ting of the ice shelves is thought to be the ultimate driver of change(2,3), motivating a recent focu

57 acilitate ongoing and future research on the ultimate drivers of GS evolution in this well-studied No

58 carnivore, and to examine the proximate and ultimate drivers of this behaviour.

59 Fifteen experts thought that the DOE's ultimate durability target of 8,000 hours would be met b

60 ng allelic status of chromosomes 1p and 11q; ultimate duration of therapy was determined by overall r

61 uman activities on animal behaviour, yet the ultimate ecological consequences of these behavioural sh

62 numerous factors that can dampen or prevent ultimate ecosystem consequences.

63 n-mediated up-regulation of GADD45alpha, the ultimate effector protein of this stress signaling casca

64 The ultimate effectors of this axis are members of a family

65 rs; despite substantial theoretical work the ultimate efficiency of this relativistic high-order-harm

66 related sustainable development goals, in an ultimate effort to enhance population health and well-be

67 rainstem before binge drinking predicted the ultimate emergence of compulsivity.

68 h profiling across the fiber axis), with the ultimate end of employing it for brain tissue analysis.

69 ican Heart Association acknowledges that the ultimate endgame would be an end to all tobacco and nico

70 uations are particularly concerning when the ultimate endpoint involves genetic/genomic interpretatio

71 species' genomes de novo fail to achieve the ultimate endpoint to produce contigs, each representing

72 We discuss testable hypotheses for the ultimate (evolutionary) and proximate (mechanistic) caus

73 problem from both proximate (molecular) and ultimate (evolutionary) angles.

74 n many systems given that hydroperiod is the ultimate factor determining the presence of an aquatic s

75 ising system for investigating proximate and ultimate factors of phenotypic variation.

76 Then, using multiple examples, we discuss ultimate factors that have driven the evolution of color

77 the beta-cells, possibly resulting in their ultimate failure and onset of type 2 diabetes.

78 ering lead to lack of tissue integration and ultimate failure of engineered grafts.

79 er monothonic and cyclic tensile loads up to ultimate failure.

80 ntify a period of viable persistence and the ultimate fate of B. bacteriovorus inside phagocytic cell

81 believed to be important for determining the ultimate fate of beta-cells and hence progression of typ

82 emonstrate that the spatial distribution and ultimate fate of microplastics are strongly controlled b

83 In some developing tissues, death is the ultimate fate of over 80% of generated cells.

84 Here transport pathways and the ultimate fate of the Irminger Current water from the con

85 The ultimate fate of these micronutrients will depend on the

86 stablish the niche that will determine their ultimate fate.

87 is timing can play a role in determining the ultimate fates and unique characteristics of distinctive

88 ramic electrolytes (0.13%) and a much larger ultimate flexural modulus (7.8 GPa) than pure polymer el

89 nts catastrophic failure and leads to higher ultimate flow stress.

90 (+30.7%, P = 0.0029), but did not change the ultimate force (P < 0.01).

91 suggest the Atlantic SST variability is the ultimate forcing leading to changes in the atmospheric c

92 in certain social contexts, the proximal and ultimate function of beliefs and desires is social inclu

93 n environment is critical in determining the ultimate function of the CD in CBX8 association.

94 major breakthroughs in neuroscience but its ultimate function remains surprisingly unclear: An actua

95 e the view that stimulatory peptides are the ultimate gatekeepers of puberty.

96 tive electrodes (ISEs) that could become the ultimate, generally applicable SC, which in combination

97 d guide the reader to discover the patient's ultimate genetic diagnosis.

98 Mutation is the ultimate genetic source of evolution and biodiversity, b

99 An ultimate goal for those engaged in research to develop i

100 The ultimate goal in the understanding of complex chemical p

101 explanations for macroscopic phenomena, our ultimate goal in this review paper is to critically eval

102 ng chemistries for self-healing polymers, an ultimate goal is to create high strength and stiffness c

103 nues to be of considerable interest since an ultimate goal is to more selectively target the aberrant

104 Preventing the onset of caries is the ultimate goal of a caries management plan.

105 With the ultimate goal of a computational framework for soft robo

106 lls can be recognized and targeted, with the ultimate goal of achieving an HIV-1 cure.

107 for hypothesis-driven approaches toward the ultimate goal of adult heart regeneration and repair.

108 ough the evidence they have created with the ultimate goal of advancing health.

109 for harnessing cortical plasticity with the ultimate goal of aiding recovery from brain injury or di

110 additional models of hyposalivation with the ultimate goal of applying this technology in humans.

111 framework for further studies of RGAs for an ultimate goal of assisting breeders in improving resista

112 e whether we are making progress towards the ultimate goal of autonomous discovery.

113 te whether we are making progress toward the ultimate goal of autonomous discovery.

114 o studies using Raman spectroscopy, with the ultimate goal of clinical translation for patient strati

115 The ultimate goal of combining immunotherapy with radiothera

116 This study represents the first step to the ultimate goal of developing a cost-effective manufacturi

117 The ultimate goal of developing an integrated molecular clas

118 ationships in R14del cardiomyopathy with the ultimate goal of developing innovative disease-specific

119 ing Gag-small molecule interactions with the ultimate goal of developing of a new class of pharmaceut

120 me prediction in CHR-P individuals, with the ultimate goal of developing staged treatment approaches

121 er genes, research is far from achieving the ultimate goal of discovering a complete catalog of genes

122 The ultimate goal of Down syndrome (DS) research is to desig

123 y of a country is a pathway to achieving the ultimate goal of eradication.

124 dating actions of all stakeholders, with the ultimate goal of evidence-based, reproducible, generaliz

125 ultures from human peripheral blood, with an ultimate goal of examining interindividual heterogeneity

126 ugar and nucleobase, part-by-part-toward the ultimate goal of forming RNA and DNA by polymerization.

127 , but also in humans in order to provide the ultimate goal of giving the right drug at the right dose

128 explaining the related properties, with the ultimate goal of harnessing that knowledge in applicatio

129 current obstacles and prospects towards the ultimate goal of highly stable and reliable real-time mi

130 beyond more conventional therapies with the ultimate goal of HIV-1 elimination when combined with ot

131 exposures in psychiatric research, with the ultimate goal of identifying modifiable risk factors and

132 emergent neurotechnologies can approach the ultimate goal of illuminating chronic brain activity wit

133 With the ultimate goal of improving current vaccines, we aim to b

134 FI) and photoacoustic imaging (PAI) with the ultimate goal of improving diseases diagnosis and manage

135 With the ultimate goal of improving drought resistance in turfgra

136 help surgeons improve their skill, with the ultimate goal of improving patient outcomes.

137 loping accelerated vascular damage, with the ultimate goal of improving primary prevention and reduci

138 l conditions or injuries in humans, with the ultimate goal of improving the health and development of

139 cation corrections and retractions, with the ultimate goal of increasing confidence in the papers we

140 The ultimate goal of machine learning-based myoelectric cont

141 with existing modeling techniques, with the ultimate goal of making future drug-disease models more

142 identification of chemical compounds is the ultimate goal of mass spectrometry analyses.

143 The ultimate goal of metabolic engineering is to produce des

144 Allograft tolerance is the ultimate goal of organ transplantation.

145 tion of gut microbiota-polyphenols, with the ultimate goal of potential developing dietary polyphenol

146 ial chicken and turkey populations, with the ultimate goal of refining surveillance in these populati

147 utic strategies to induce division, with the ultimate goal of regenerating heart tissue after a myoca

148 Our study thus contributes to the ultimate goal of replacing blood transfusion with a manu

149 ain activity with animal movements, with the ultimate goal of resolving the relationship between neur

150 Here, we review progress towards the ultimate goal of safely reducing disease activity and pr

151 itopes for their protective efficacy with an ultimate goal of selecting the most efficacious targets

152 The ultimate goal of this new PrEP research agenda is to exp

153 on of antibody-drug conjugates (ADCs) as the ultimate goal of this research program.

154 een risk factors and PEDV outbreaks with the ultimate goal of training predictive models and to ident

155 c diseases in experimental systems, with the ultimate goal of treating human disease.

156 WHERE NEXT?: The ultimate goal of understanding the genetic architecture

157 The ultimate goal should be to prohibit or more closely regu

158 n the intact dystrophin gene locus, with the ultimate goal to elucidate dystrophin protein function a

159 idity and accuracy of their studies with the ultimate goal to improve the accuracy of IOL power calcu

160 tting for patients with primary GBM, with an ultimate goal to prevent or delay recurrence and prolong

161 king action selection efficiently track some ultimate goal, whether fitness or another utility functi

162 ts will continue the journey to achieve this ultimate goal.

163 Our ultimate goals are to: 1) define distinct SMC phenotypes

164 ovel NIRF nanoprobes has been developed with ultimate goals of addressing unmet medical needs.

165 and dimensional control has been one of the ultimate goals of contemporary materials science and che

166 Our ultimate goals of database development are to provide in

167 While lithium metal represents the ultimate high-energy-density battery anode material, its

168 citation patterns that were dependent on the ultimate impact of the citing paper itself; publications

169 f malnutrition certainly contributed to this ultimate impact.

170 -protein subunits among stimuli with similar ultimate impacts, which may facilitate stimulus-specific

171 to glucose stimulation has been studied for ultimate integration into closed-loop insulin delivery o

172 tor platform is scalable and can harness the ultimate level of light-matter interactions for potentia

173 nd DNA ligase III/XRCC1 complex catalyze the ultimate ligation step following DNA polymerase (pol) be

174 In quantum optics, the ultimate limit of a weak field is a single photon.

175 ingle molecule (SM) detection represents the ultimate limit of chemical detection.

176 er films with wafer-scale homogeneity in the ultimate limit of monolayer thickness by growing films a

177 The single-atom bit represents the ultimate limit of the classical approach to high-density

178 ecently, we theoretically predicted that the ultimate limit of visible photon guiding can be achieved

179 Such light guiding at the ultimate limit provides more possibilities to miniaturiz

180 onator, which is widely considered to be the ultimate limit to Q in silicon MEMS devices.

181 Heisenberg uncertainty relation presents an ultimate limit to the precision by which one can predict

182 As a step toward the ultimate limits in data density, the development of an e

183 However, the ultimate limits of liquid AP-MALDI in sample throughput

184 ent-like antimicrobial peptides that are the ultimate line of defense against carbapenem-resistant pa

185 , yield strain, yield load, ultimate strain, ultimate load, resilience, and toughness in both stance

186 rmation rate in DSS animals as well as lower ultimate load.

187 The ultimate mass resolution and accuracy are delivered by F

188 While single-molecule sensing has offered ultimate mass sensitivity at the precision of individual

189 ty to predict phenotype from genotype is the ultimate measure of our understanding of genetic archite

190 What we do not know is the ultimate mechanism of action; that is, how these drugs i

191 interaction with bacteria tell us about the ultimate mechanisms by which these antibiotics kill bact

192 ight key knowledge gaps in the proximate and ultimate mechanisms driving life history variation, and

193 s more than proximate mechanisms: It exposes ultimate mechanisms valid to all scales, from cells in c

194 iversal substrates and paves the way for the ultimate miniaturization of electronics.

195 gested that a 'flat' competition between the ultimate motor actions might also explain these results.

196 s been enhanced and phase became stable, but ultimate nanocrystals still retained the hexahedron cube

197 In fact, the ultimate need for specificity is critical for the proper

198 The ultimate objective for these types of studies is predict

199 notypes as those observed in humans with the ultimate objective of assessing the effectiveness of pha

200 The ultimate objective was to develop a framework to improve

201 also predicts the solution structure of the ultimate organozinc reagent.

202 phyletic, but a consensus scenario for their ultimate origin is still lacking.

203 nts who were initially comatose, in whom the ultimate outcome is unclear.

204 The ultimate outcome of infection was driven by the recruitm

205 between HSV-1 and host, which determines the ultimate outcome of infection.

206 mical signatures related to the severity and ultimate outcome of the infection.

207 between differential land-use conditions and ultimate outcomes for honey bee colonies has been elusiv

208 urate, noninvasive, and early forecasting of ultimate outcomes for NSCLC patients receiving ICIs.

209 ich acted as the oxygen atom carrier for the ultimate oxidant O(2) .

210 relying on green oxidants H2O2 and O2 as the ultimate oxygen source.

211 ncoded biosynthesis of proteins provides the ultimate paradigm for high-fidelity synthesis of long po

212 Finally, (iv) an ultimate pathway might encounter failure of effective mo

213 nt for song learning outcome and inform that ultimate performance in part depends on factors experien

214 The ultimate performance of flow-based measurements in micro

215 of HAAs in meat was significantly related to ultimate pH (r = -0.80), glucose concentration (r = 0.60

216 taken from 36 samples of pork with different ultimate pH.

217 ment systems should be designed based on the ultimate pharmaceutical concentration in ureolyzed urine

218 fferent cooperating events can influence the ultimate phenotype in these different familial leukaemia

219 nobiosensor strategies that would act as the ultimate point-of-care test for the personalized cancer

220 However, the ultimate position and mechanisms underlying nucleosome e

221 d to 3-pentadienyl cations, control over the ultimate position of the alkene, the potential for high

222 s nascent HCs but it does not determine HCs' ultimate positions, indicating that Emx2 mediates bidire

223 kgrounds in these studies may undercut their ultimate potential for both public health and precision

224 Realizing its ultimate potential requires simultaneous attainment of b

225 ered structures of LiNiB compounds make them ultimate precursors for exfoliation studies, thus paving

226 e plays an essential role in determining the ultimate product selectivity.

227 nitiates the reaction cascade leading to the ultimate products.

228 e nature of evidence in epidemiology and the ultimate purpose of epidemiologic inquiry.

229 In this way, GTPBP5 provides an ultimate quality control checkpoint function during mtLS

230 istory and demonstrate its importance to the ultimate quality of additively manufactured materials.

231 lotting is enough to prevent bleeding is the ultimate question for treating bleeding disorders.

232 The review ultimately gives answers to the ultimate question: "Are they really needed or can bulk m

233 se two-way assisted capacities represent the ultimate rates that are reachable without quantum repeat

234 functionalization reactions may lead to the ultimate realization of molecular editing: the freedom t

235 s paper presents a simple method to estimate ultimate recovery factors (URF) of ultratight reservoirs

236 strategy for severe burn patients, but their ultimate rejection limits their potential efficacy and u

237 it has been challenging to disentangle their ultimate relationships.

238 p ligand migration from the buried cavity to ultimate release through an opening between the F/G-, H-

239 sent useful molecular markers to predict the ultimate response of pituitary adenomas to BIM-23A760.

240 Ultimate responsibility and accountability for AI remain

241 gen atom transfer, radical fluorination, and ultimate restoration of the enone.

242 The ultimate result of the actions of these three enzymes is

243 ely in virulence, a key determinant of their ultimate risk to public health.

244 One potential pathway to find an ultimate rule governing our universe is to hunt for a co

245 intrinsic connections reflect an alternative ultimate rule of our universe, i.e., the principle of le

246 uired for maximum enhancement as well as the ultimate sensitivity of the technique.

247 We find that peatlands reach their ultimate shape first at the edges of peat domes where th

248 environment, and the deep seafloor is their ultimate sink compartment.

249 Oceans are the ultimate sink for many of the over 100 million man-made

250 mplasmic domain, wherein the S-cells are the ultimate sink.

251 rical energy conversion and may represent an ultimate solution for mobile power supply.

252 egardless of alginate fouling, suggesting an ultimate solution to eliminating the irreversible membra

253 ar energy for battery charging represents an ultimate solution toward low-cost, green, efficient and

254 raceless solid-phase synthesis represents an ultimate sophisticated synthetic strategy on insoluble s

255 Mutation is the ultimate source of all genetic novelty and the cause of

256 Light as a trigger provides the ultimate spatial and temporal control of activation.

257 of a wide range of nanoscale materials with ultimate spatiotemporal resolution.

258 We evaluated viral interference with the ultimate step in cytotoxic T cell function, the death of

259 The ultimate step in lysine biosynthesis, the NAD(+)-depende

260 The key and ultimate step is a double palladium-catalyzed, carbon mo

261 g an unexpected contribution of USP16 to the ultimate step of 40S synthesis.

262 with regard to recent benchmark results and ultimate storage targets in this field.

263 s were toughness (over 2.5 times larger) and ultimate strain (over 1.5 times longer).

264 increased from young to adult age, while the ultimate strain and amount of glycosaminoglycans decreas

265 l femur stiffness, yield strain, yield load, ultimate strain, ultimate load, resilience, and toughnes

266 on on elastic modulus, tensile strength, and ultimate strain.

267 modulus (E(100%) < 700kPa) as well as large ultimate strains (dL/L(0) up to ~ 400 %), toughnesses (U

268 at the size, thickness, elastic modulus, and ultimate stress in both the radial and circumferential d

269 coincided with maximum tissue strength (i.e. ultimate stress), whilst peak fibril strain occurred aft

270 Here, we quantified the expression and ultimate success of diverse salmon emigration behaviors

271 The ultimate success of immunotherapy in the CNS will requir

272 identify failure dynamics that will lead to ultimate success or failure.

273 Metastasis is the ultimate "survival of the fittest" test for cancer cells

274 most respondents anticipated that the DOE's ultimate target of $30/kW would be met by 2050 and a pow

275 The ultimate temporal persistence of such changes remains un

276 We present estimates of ultimate tensile strength (UTS) for two engineered beta-

277 astic modulus (EM), maximum strain (MS), and ultimate tensile strength (UTS) in the 20-Gy group were

278 s were found to possess the same approximate ultimate tensile strength (UTS) via uniaxial tensile elo

279 tem results in Zn-0.8Li-0.4Mg alloy with the ultimate tensile strength 646.69 +/- 12.79 MPa and Zn-0.

280 concentration of the essential oil increased ultimate tensile strength and contact angle but decrease

281 n) and 3.5-fold (transverse direction) lower ultimate tensile strength in comparison with Hastalex (p

282 The ultimate tensile strength was 1165 MPa with ductility of

283 icro-tensile testing results showed that the ultimate tensile strength, the elongation at failure, an

284 ng's modulus, yield strength, and especially ultimate tensile strength.

285 ed P19 cells to neural progenitors and their ultimate terminal differentiation into neurons, ectopic

286 towards a parasitic lifestyle - will be our ultimate test of truly understanding the genetic and gen

287 chemical euthyroidism may help to achieve an ultimate therapeutic effect.

288 Topology-protected surface transport of ultimate thinness in three-dimensional topological insul

289 These results set an ultimate timescale of the exciton formation in TMDs and

290 ents in bone anatomy, mobility patterns, and ultimate tooth survival)?

291 However, other properties such as ultimate toughness, tensile strength, poroviscoelastic r

292 ed transcription factors (SRTFs) control the ultimate transcriptional output of signaling pathways.

293 omic biomarker of risk of TB progression for ultimate translation into a point-of-care diagnostic.

294 The ultimate translational beneficial effect of such phytoco

295 hat the changes in PP2A-B55 activity are the ultimate trigger.

296 the preparation of quantum materials in the ultimate two-dimensional limit(1,2).

297 oach revealed the diversity, complexity, and ultimate uniqueness of mutational landscapes, differentl

298 Stroke theranostics, the ultimate vision of synchronising tailored therapeutic st

299 genome sequencing project or with respect to ultimate whole genome assembly strategies.

300 As graphene nanoribbons of ultimate width, they are valuable atom-precise model sys