ライフサイエンスコーパス: underpin

1 cular remodeling with a strong physiological underpinning.

2 ection of disorders with a complex molecular underpinning.

3 This process is thought to underpin a myriad of cellular processes in plants that a

4 Temporary directing groups (TDGs) underpin a range of C-C bond activation methodologies; h

5 s proton-coupled electron transfer, and they underpin a wide variety of biological processes, includi

6 gical innovation, and from ca. 6400-5900 BP, underpinned a ~four-fold human population growth.

7 case study, we dissect the regulatory forces underpinning a key step along the developmental decision

8 This finding underpins a crucial role of Glu340 in interdomain commun

9 tify a gold-assisted exfoliation method that underpins a universal route for producing large-area mon

10 aroreceptor discharge at ventricular systole underpins afferent signalling of cardiovascular arousal.

11 ching males lack functional aicda genes that underpin affinity maturation of antibodies.

12 reduction in mTOR activity may not directly underpin Ag-expTh1 cell loss and exhaustion during malar

13 Evidence-based conceptual frameworks underpinned all Exemplars research activities.

14 mology-directed repair (HDR) mechanisms that underpin alternative lengthening of telomeres (ALT).

15 D14L-dependent signalling mechanisms, underpinning AM symbiosis are unknown.

16 y diverse in sequence, and this polymorphism underpins an important mechanism of self/nonself discrim

17 me cGAS induces innate immune responses that underpin anti-microbial defenses and certain autoimmune

18 ur understanding of the molecular rules that underpin antigen recognition by TCRs and have important

19 es new insights into genetic risk mechanisms underpinning anxiety and related psychiatric disorders.

20 ine metabolism via redox buffering of the ER underpins appressorial adhesion and rice cell invasion a

21 The possible cellular mechanism underpinning ataxia in this global Asic5 knockout model

22 The mechanisms underpinning attentional deficits are only partially und

23 s to assess two generic cognitive operations underpinning auditory scene analysis-sound source segreg

24 n particular, that motor representations may underpin automatic false-belief tracking.

25 ns of genomics to investigate the mechanisms underpinning bee population declines and to improve the

26 Our results demonstrate that NA underpins behavioral and computational responses to unce

27 acts, enabling coherent face processing that underpins behaviour and cognition.

28 ulocytic inflammation, but on the other hand underpinning beneficial epithelial repair responses, whi

29 ated bacteria showed downregulation of genes underpinning biofilm signaling (luxS) and regulation (bs

30 The types of research underpinning biological control approaches and challenge

31 The underlying molecular interactions that underpin biomolecular LLPS have been of increased intere

32 Frustration is thought to underpin biomolecular recognition and the flexibility of

33 into abnormal conformers (PrPSc), with PrPSc underpinning both transmission and synaptotoxicity.

34 xtensive characterization of complexity that underpins both the healthy and malignant bone marrow mic

35 key role for inflammation and ER signalling underpinning BVZ + chemotherapy responsiveness.

36 Models were underpinned by a common training set of 1,746 chemicals

37 Muscle adaptations to exercise are underpinned by alterations to the abundance of individua

38 ensory, homeostatic and semantic processing, underpinned by atrophy in a thalamo-cortico-striatal net

39 e 2D to 3D growth transition in P. patens is underpinned by complex auxin-cytokinin crosstalk that is

40 ting theories suggest that this "savings" is underpinned by different mechanisms, including a memory

41 nd negative future-related cognitions may be underpinned by distinct neuroanatomical substrates.

42 Our results suggest that VDAC is underpinned by learned value signals that modulate spati

43 Such advances will be underpinned by new tools that probe how immune signals a

44 iation in assemblage functional structure is underpinned by nuanced shifts in the position, shape and

45 nd execution is a prerequisite and should be underpinned by policies that include appropriate trainin

46 However, whether such changes in risk are underpinned by predictable ecological changes remains un

47 XRN2 enriches these events that we show are underpinned by protein phosphatase 1 (PP1) activity, the

48 f B cells between distinct microenvironments underpinned by specialized B cell-interacting reticular

49 ng favors efficiency over flexibility and is underpinned by specific neural mechanisms.

50 that the functional role of these systems is underpinned by structural white matter.

51 system services derived from coral reefs are underpinned by the growth and physical complexity of ree

52 s uses somatic motility of outer hair cells, underpinned by the membrane protein prestin, to expand t

53 capture regional functional effects that are underpinned by the same cognitive mechanism but are rela

54 This capillary transfer is underpinned by the transfer front of dynamic contact amo

55 rs, with distinct regimes of tumor evolution underpinned by unique sets of mutations in different com

56 However, the molecular mechanisms underpinning cancer cell plasticity are incompletely und

57 Understanding the molecular mechanisms underpinning cancer cell survival despite the oncogenic

58 This review highlights rhythms that underpin cardiac physiology.

59 tin and induce changes in accessibility that underpin cell fate decisions.

60 chloroplast-derived reactive oxygen species underpin chloroplast immunity through indirect evidence

61 However, the fundamental mechanisms underpinning cilia biogenesis and functions remain only

62 The genes and molecular mechanisms underpinning circadian clocks in multicellular organisms

63 rk analysis revealed the cellular remodeling underpinning clinical trajectories and nominated candida

64 spatially- and temporally-resolved processes underpinning complex plant-microbe interactions.

65 This may underpin conflicting predictions, found throughout the l

66 peptides demonstrate that molecular mimicry underpins cross-reactivity toward the gliadin epitopes.

67 rkers associated with inflammatory endotypes underpinning CRSsNP.

68 search into the higher-order capacities that underpin deliberation-particularly those that enable peo

69 fundamental understanding of mechanisms that underpin desired properties, but also adapting them to t

70 Our findings could underpin development of a suite of imaging tools for pla

71 Deciphering the mechanisms that underpin dietary specialization and niche partitioning i

72 ork in light of key computational principles underpinning discovery of circulating microRNAs in terms

73 to identify potentially rate-limiting steps underpinning diurnal malate mobilisation and help direct

74 anoparticle (NP) transport in the subsurface underpins environmental risk assessment and successful m

75 sm, the regulatory transcriptional landscape underpinning ER stress management is largely unmapped, e

76 ed [CO(2) ] and the genetic changes that may underpin evolutionary mechanisms with [CO(2) ] as a driv

77 et of molecular regulatory interactions that underpin exhaustion.

78 Data suggest that lower FD partly underpins FA reductions of premature birth but that othe

79 nd that the right temporal structures mainly underpin face familiarity feelings.

80 g revealed that dominant learning mechanisms underpinning flexible behavior differed across developme

81 conditions; however, the molecular processes underpinning flowering in nature remain poorly understoo

82 enhance resilience to climate change and to underpin food security, through initiatives such as inte

83 s in mediating behavior and provide a neural underpinning for Bayesian models of perception.

84 First, we provide a theoretical underpinning for empirical scaling laws reported in prev

85 antiviral activity and provide a mechanistic underpinning for its mode of action as an inhibitor of c

86 This treatment provides a theoretical underpinning for preprocessing and postprocessing method

87 sease characteristics, providing a molecular underpinning for the clinical use of these drugs in pati

88 psychiatric disorders, providing a molecular underpinning for the effects of stress in those disorder

89 e autophagy field, supplying the mechanistic underpinning for the formation of an autophagosome selec

90 The underpinning free-energy landscapes for electron bifurca

91 icates that temporal, dynamic control of ROS underpins full malignant progression and helps to ration

92 ry 8 weeks dosing, and supportive modelling, underpin further evaluation of every 8 weeks dosing in t

93 Our findings underpin future investigation of host exosome proteins a

94 his Perspective is on the ion chemistry that underpins gas-phase analytical CI methods.

95 g of transcription factors to regulatory DNA underpins gene regulation in all organisms.

96 Whilst it is evident that gut microbes can underpin host metabolic plasticity, the causal nature of

97 The mechanism underpinning how substitutions in this position modulate

98 Pan-genotype NS5A inhibitors underpin hugely successful hepatitis C virus (HCV) thera

99 and parasite transcriptional responses that underpin human monocyte-Toxoplasma encounters at the sin

100 uely suited for investigating the mechanisms underpinning human metabolic health and disease.

101 rspecies communication signalling mechanisms underpinning human-animal approach behaviour, which to d

102 d view of inflammasome signaling; mechanisms underpinning IL-1alpha, IL-1beta, IL-18, and IL-37 matur

103 rant production or function of cytokines can underpin immunopathology.

104 Increased cellular ATP underpins increased myeloid cell superoxide production a

105 Issues of trust, accountability and equity underpin Indigenous critiques of genetic research and th

106 Our study reveals a central principle underpinning intra-tumoral heterogeneity and motivates t

107 the cytoarchitectural gradient was found to underpin intrinsic effective connectivity of the MTL, bu

108 ng and repair after injury, which may partly underpin its association with OA risk.

109 Parkinson's disease (PD), but the mechanisms underpinning its effects remain unknown.

110 ated with migration and molecular mechanisms underpinning its seasonality.

111 of E. huxleyi, a characteristic that likely underpins its ability to thrive across a variety of mari

112 n for this discrepancy is that the processes underpinning lexical access to semantic knowledge may be

113 rming reproductive restraint as a key factor underpinning life-history variation.

114 The molecular conformational changes underpinning ligand activation are largely undefined.

115 hese data provide insight into the mechanism underpinning macrophage proliferation to support maligna

116 ~20% of annual global carbon fixation, they underpin major aquatic food webs and drive global biogeo

117 ain of adaptive functions and in some cases, underpinned major lifestyle transitions.

118 Lists of species underpin many fields of human endeavour, but there are c

119 et been applied to eutectic materials, which underpin many modern technologies ranging from high-perf

120 ion systems and in microfluidics, the latter underpinning many new life science technologies.

121 noparticles, including viruses and bacteria, underpins many of the biological, physical and engineeri

122 The mechanisms underpinning maternal metabolic adaptations to a healthy

123 ould reveal the degree of convergence in the underpinning mechanisms [7, 8].

124 the biochemical information processing that underpins metabolism and reproduction.

125 ate the understanding of evolutionary forces underpinning metazoan life at the limits of small physic

126 filing capabilities that decipher mechanisms underpinning microbiome function.

127 d whether exposure to circadian misalignment underpins mood vulnerability in simulated shift work.

128 se findings signal that our motor system may underpin more of social cognition than previously imagin

129 l resolution identifies cellular events that underpin mosquito immunity to malaria infection.

130 astro-esophageal pressure gradient (>10mmHg) underpinned most reflux events.

131 Studies in island systems underpin much of our knowledge of macroevolution.

132 The chemoselectivity of molecular catalysts underpins much of modern synthetic organic chemistry.

133 The dielectric nature of polar liquids underpins much of their ability to act as useful solvent

134 To disentangle the physiological mechanisms underpinning multistress tolerance to desiccation and fr

135 tanding aging and cancer, the processes that underpin mutational selection in normal tissues remain p

136 s to interact with multiple in vitro targets underpinning neurodegeneration points to the potential i

137 ar, genetic and epigenetic requirements that underpin normal placentation has remained remarkably und

138 Dynamic RNA-protein interactions underpin numerous molecular control mechanisms in biolog

139 The brain mechanisms underpinning object perception are yet to be understood.

140 rovide new insights into the strategies that underpin obstacle avoidance in birds.

141 strong implications not only for the genetic underpinning of Alzheimer's disease but also for how we

142 link animal and human studies on the neural underpinning of attention in aging and underscore the im

143 tific community to understand the biological underpinning of COVID19 pathophysiology.

144 l states and genes of interest to expose the underpinning of developmental mechanisms.

145 at in order to account for the psychological underpinning of human behavior, one should also consider

146 lipid accumulation constitute the metabolic underpinning of nonalcoholic steatohepatitis (NASH).

147 Here, we describe the potential underpinning of SAF microscopy and spectroscopy, particu

148 It may form part of the neural underpinning of the well-recognized but poorly explained

149 cardiovascular disease (CVD), the molecular underpinning of this connection remains enigmatic.

150 nsive framework that captures the structural underpinning of this prediction.

151 ance has had little impact on the conceptual underpinning or practice of biological control.

152 Levels of gene expression underpin organismal phenotypes(1,2), but the nature of s

153 Distinctions between cell types underpin organizational principles for nervous system fu

154 to provide insights into the processes that underpin osmolyte synthesis and transport, but the main

155 the reader with intervening discoveries that underpin our current understanding of muscle microcircul

156 to delineate and quantify physical processes underpinning particle behavior but also provides direct

157 ly involved parts of the "social brain" that underpin perspective-taking and self-other distinction.

158 sally associated with the embodied processes underpinning perspective-taking.

159 Here, we investigate how organization underpins phage lambda development and decision-making b

160 r understanding of the basic principles that underpin pHLA selectivity and exemplify a number of mole

161 cells play essential roles in human health, underpinning physiological processes such as immunity, o

162 To inform the evidence-base underpinning policy decision making, mathematical and he

163 We reveal two distinct mechanisms underpinning potentially disparate pathogenic pathways o

164 s defined a core 192-nt localisation element underpinning precise mRNA targeting to sites of filopodi

165 is a fundamental feature of living systems, underpinning processes that range from transport through

166 While bacteria-stimulated metamorphosis underpins processes such as the fouling of ship hulls, a

167 The mechanisms underpinning protein aggregation and toxicity are introd

168 covery of an important mechanistic principle underpinning psychedelic-induced altered states.

169 represent distinct biological risk profiles underpinning PTSD.

170 viding new insights into the molecular basis underpinning quantitative traits and knowledge necessary

171 res an urgent assessment of how biobanks can underpin research by preserving microbiome samples and t

172 This necessitates a standard data format to underpin research, particularly in line with the FAIR da

173 Identifying the patterns and mechanisms underpinning responses to temporal variation in precipit

174 ng definitions lack a principled statistical underpinning, resulting in misleading tree distances tha

175 ro We anticipate these findings will help to underpin retinal organoid technology, which holds much p

176 ct of intensive research, but the mechanisms underpinning robustness remain unclear.

177 Finally, we discuss possible mechanisms underpinning RTK ligand bias.

178 iple beneficiaries into the decision problem underpinning SCP.

179 It also underpins SemMedDB, a literature-scale knowledge graph b

180 riguing new alternatives to design materials underpinning several energy conversion technologies.

181 Cell-cell contacts often underpin signaling between cells.

182 dynamically sorted into membrane domains to underpin signaling in response to extracellular stimuli.

183 Vesicle exocytosis underpins signaling and development in plants and is vit

184 The deletion data underpin simulations indicating that multiple postreplic

185 ealed complex protein networks that possibly underpin sorghum responses to water limitation.

186 hat metabolic control by the circadian clock underpins specific hallmarks of cancer metabolism.

187 ologic responses, yet the precise mechanisms underpinning specificity of these responses remain uncle

188 novel insight into the biological processes underpinning spontaneous CLL regression, with implicatio

189 wever, the molecular identity and mechanisms underpinning stem solidness have not been identified.

190 More research evidence is needed to underpin strategies identified as encouraging such as Na

191 erapies and to better understand the biology underpinning such treatments, we have used gnotobiotic m

192 Typically, the molecular mechanism that underpins such a decoration process involves a three-com

193 we suggest possible crystal growth processes underpinning synthetic control of defect nanodomains.

194 To understand the molecular events underpinning TGF-beta1-induced fibrogenesis, we examined

195 The present results underpin that both processes recruit the same neural net

196 Genomic evidence is increasingly underpinning that hybridization between taxa is commonpl

197 Our results underpin the ability of CENP-A chromatin to establish an

198 uction of virulence factors in the intestine underpin the biofilm hyperinfectivity phenotype.

199 short-cut to acquiring adaptive information, underpin the cumulative cultural evolution that has cont

200 berrant central glutaminergic signalling may underpin the depressive-like behaviours that result from

201 The genes that underpin the development and function of stomata have be

202 of experiments and exploited this finding to underpin the development of a pervaporation (PV) desalin

203 This knowledge will underpin the development of new delivery strategies for

204 of the host-pathogen interaction that might underpin the development of new management strategies fo

205 ti-VEGFs and to identify key mechanisms that underpin the differential outcomes observed in the clini

206 y sex-specific molecular etiologies that may underpin the dramatic sex differences in cancer incidenc

207 Identifying the mechanisms which underpin the enhanced protection induced by such strateg

208 assembly of host-associated communities may underpin the evolution and maintenance of microbial inte

209 emergence of these structures is thought to underpin the evolutionary acquisition of complex motor a

210 These properties appear to underpin the favorable activity and tolerability profile

211 endous variety of cell biology features that underpin the function of these multitasking immune cells

212 rmation about the electronic properties that underpin the functions of these frameworks.

213 epithelium and neighboring mesenchymal cells underpin the generation of different pancreatic cell typ

214 etion of anti-oxidant elements such as zinc, underpin the high incidence of CIN in domestic cats.

215 and the complex biopsychosocial factors that underpin the infection.

216 by which the tuning of surface charge could underpin the mitoprotective properties of SS-31, includi

217 . In silico mutagenesis examinations further underpin the molecular basis of HI/HA dominant mutations

218 he associated potential energy landscape, we underpin the molecular origin of the kinetic advantages

219 a cooperative process, the kinetics of which underpin the orderly morphogenesis of domain patterns on

220 itatively revealed potential mechanisms that underpin the phenomenological Monod parameters: the maxi

221 Our results underpin the pivotal role of the physicomechanical prope

222 and developed by the microfluidic community underpin the printing of sub-100 mum enclosed microchann

223 Leaf photosynthetic traits underpin the rate of production of biomass and yield and

224 ngth of evidence supporting three assertions underpinning the ameliorating benefits of Se: (1) dietar

225 rformed studies to understand the mechanisms underpinning the anastomosis of the host vasculature wit

226 ence demonstrates that such responses exist, underpinning the associations of particular gammadelta T

227 Studies evaluating the mechanisms underpinning the biomagnification of polychlorinated bip

228 the dots" between the fundamental chemistry underpinning the cascade reactions of lipid peroxidation

229 for the elucidation of the enzyme mechanism underpinning the complex process of GPA cyclization and

230 titute and dissect the substrate specificity underpinning the cytoplasmic O-glycosylation pathway tha

231 nding of the underlying molecular mechanisms underpinning the development of the gonad phenotypes of

232 amined the molecular and cellular mechanisms underpinning the differentiation of cytotoxic CD4(+) T c

233 to examine whether the cognitive mechanisms underpinning the effects of minimal groups overlapped wi

234 To elucidate mechanisms underpinning the effects of short-term TRF, we investiga

235 The mechanisms underpinning the evolution of new biosynthetic pathways

236 thesized to trigger a CD8(+) T-cell response underpinning the hypersensitivity.

237 The mechanisms underpinning the impact of BP exposure on brain structur

238 However, the cellular mechanism underpinning the induction of SOCS isoforms and their ro

239 minate the cognitive and emotional processes underpinning the interpersonal difficulties associated w

240 unconstrained as it is by the collinearities underpinning the latitudinal diversity gradient.

241 ) are versatile mesenchymal cell populations underpinning the major functions of the skeleton, a majo

242 compounds, identifying the specific residues underpinning the mechanism of 1229U91 binding.

243 The elucidation of immune mechanisms underpinning the parasitic infections, some of which are

244 The protein profiles underpinning the pathological subtypes and metastatic be

245 pproaches to investigate the molecular rules underpinning the reactivity patterns of pHLA-targeting b

246 esponsive proteins, which revealed processes underpinning the various metabolic changes seen during c

247 Our empirical evidence thus underpins the cardinal role of rapid sea ice decline and

248 the execution of this iterative process that underpins the development of new bioactive agents.

249 that restriction of protein dynamics in PBP2 underpins the ESC resistance of N. gonorrhoeae.

250 mation from multiple cues, a phenomenon that underpins the evolution of multicellularity and developm

251 Coral is the life-form that underpins the habitat of most tropical reef ecosystems,

252 This unconventional stereodetermining step underpins the high enantioselectivities and regioselecti

253 ggerated prefrontal cortical activity likely underpins the inflexible thinking and rigid behaviors ex

254 ndent inflammatory cell death mechanism that underpins the innate immune response against pathogens a

255 tion in the maternal vascular landscape that underpins the maternal and downstream fetal pathology to

256 Limited clinical benefit underpins the need for improved understanding of resista

257 Metabolism underpins the pathogenic strategy of the causative agent

258 We sought to discover what underpins the poor Tfh cell response in ageing and wheth

259 d T->C mutations in the Amish, which seem to underpin their overall reduction in DNMs.

260 ion and identifying the core mechanisms that underpin their pathogenicity.

261 ulti-layered substrate-recognition mechanism underpinning their divergent genomic methylation activit

262 Yet, the cellular mechanisms underpinning their immunity remain to be elucidated.

263 crodomains persisted in the small processes, underpinning their resemblance to physiological inositol

264 EC and their important partnership with NPC, underpinning their unique role in maintaining a healthy

265 We provide a review of the literature, the underpinning theories including our contributions, and w

266 anisms and aberrant signaling processes that underpin these conditions remains scarce.

267 n and the extent to which structural changes underpin these effects are currently unknown.

268 vations, physical constraints and model data underpin these findings.

269 ocumented, the physiological mechanisms that underpin these patterns remain unclear.

270 on, and the corticosubcortical circuits that underpin these processes, might put adolescents at risk

271 wever, the molecular and cellular mechanisms underpinning these ageing processes remain unclear.

272 -mediated responses; however, the mechanisms underpinning these changes in humans are not fully under

273 upon using these agents, the exact mechanism underpinning these changes is unknown.

274 summarize the background and recent findings underpinning these concepts with a focus on two major pa

275 ition on parasite fitness and the mechanisms underpinning these effects are relatively unexplored.

276 piratory infections; however, the mechanisms underpinning these interactions are still unclear.

277 One major challenge underpinning these issues is the current payment system,

278 Underpinning these observations, we show that collaborat

279 uggest a cytoskeleton-based mechanism likely underpins these observations.

280 The molecular mechanism that underpins these reprogramming processes remains largely

281 to determine the thermodynamic factors that underpin this activity.

282 more insight into the protein networks that underpin this diverse functionality, molecular panning a

283 Therefore, understanding mechanism(s) that underpin this impairment is a critical gap.

284 fficacious and the molecular mechanisms that underpin this remain largely unknown.

285 ermore, it is unknown which brain mechanisms underpin this type of learning.

286 nto how midbrain DA neuron heterogeneity may underpin this variety of behavioral symptoms.

287 external environment to the genomic changes underpinning this improvement are unknown.

288 tatus of the cell, the regulatory mechanisms underpinning this phenomenon are unclear.

289 To explore the molecular drivers underpinning this process, we correlated these findings

290 compartmentation of beta(3)-AR/cGMP signals underpinning this protection in health and disease remai

291 However, the peripheral mechanisms underpinning this recovery are largely unknown, limiting

292 the oxygen-sensing and -signaling mechanisms underpinning this response have remained unknown.

293 g a deeper understanding of the design rules underpinning this strategy is highly desirable.

294 iled insights into the biochemical processes underpinning this unusual enzyme's wide-ranging antivira

295 Here we have reanalysed the evidence underpinning those claims and apply more data to the que

296 has been long-standing interest in processes underpinning thymus generation and the potential to mani

297 It points to a genetic underpinning to clinically predicted risk of attempting

298 APOBEC3G and its antagonism by HIV-1 Vif has underpinned two decades of research on the host-virus in

299 Opsins are genes underpinning vision in animals.

300 ggests an important and broad mechanism that underpins Wolbachia-mediated pathogen blocking.