ライフサイエンスコーパス: unresolved issue

1 ith aortic arch involvement (AAI) remains an unresolved issue.

2 ydrogen bonding in solution has long been an unresolved issue.

3 how the spirochetes cross the BBB remains an unresolved issue.

4 iming CD8(+) T cells has been a longstanding unresolved issue.

5 rdiovascular diseases has emerged as a major unresolved issue.

6 es to this compound remains an important and unresolved issue.

7 the vertebral column remains a fundamental, unresolved issue.

8 c dermatitis and asthma, is an important but unresolved issue.

9 e Ca(2+) spark terminates remains a central, unresolved issue.

10 D4 T cells to allograft rejection remains an unresolved issue.

11 tal influences on structure remains a major, unresolved issue.

12 stant metastases remains a controversial and unresolved issue.

13 toward a specific direction remains a major unresolved issue.

14 vivo values has long been remained a largely unresolved issue.

15 n of ventricular tachycardia is an important unresolved issue.

16 the high vein graft failure rates remain an unresolved issue.

17 en spacing and size of such structures is an unresolved issue.

18 continents, to elucidate this long-standing unresolved issue.

19 established during development is a largely unresolved issue.

20 nteractions respond to mechanical cues is an unresolved issue.

21 nduction into damaged sites has long been an unresolved issue.

22 ays to spatial vision is a long-standing and unresolved issue.

23 silver ions (Ag(+)) in vivo has remained an unresolved issue.

24 minant of conformation is a long-running and unresolved issue.

25 out of alloimmunity has been a longstanding unresolved issue.

26 CENP-A (CID in Drosophila) is a fundamental, unresolved issue.

27 s exact role in this process has remained an unresolved issue.

28 eck squamous cell carcinoma, and to describe unresolved issues.

29 in homeostasis and cancer development remain unresolved issues.

30 a unique opportunity to shed light on these unresolved issues.

31 g of tree physiology and scaling, indicating unresolved issues.

32 ins diverts attention from these fundamental unresolved issues.

33 t developments relevant to several important unresolved issues.

34 ized and experiments designed to address its unresolved issues.

35 data that throws light on several previously unresolved issues.

36 ble data to encourage attention on important unresolved issues.

37 of the normalization model, there are three unresolved issues.

38 (BCP) method, which addresses some of these unresolved issues.

39 broad range of findings and raises important unresolved issues.

40 materials remain fundamental, yet presently unresolved, issues.

41 Further research is critical to answer three unresolved issues: (1) What are the equivalent doses for

42 An unresolved issue about many neurodegenerative diseases i

43 A critical unresolved issue about the genotoxic stress response is

44 erature supporting its use and summarize the unresolved issues affecting broader application of this

45 safety and efficacy, and discuss some of the unresolved issues and controversies of each approach.

46 Unresolved issues and directions for future study are pr

47 In the process, we highlight some key unresolved issues and discuss how they might be addresse

48 on of QseB/QseC studies and describe several unresolved issues and future directions.

49 d post-procedural evaluation and management, unresolved issues and future perspectives.

50 We conclude by articulating unresolved issues and offer a future agenda for the scie

51 We also discuss some of the unresolved issues and potential future directions.

52 Here, we discuss unresolved issues and propose research directions to enh

53 nd summarizes subsequent progress, promises, unresolved issues, and challenges of the field.

54 ndings and some of the unanswered questions, unresolved issues, and controversies that remain.

55 l requirements, characteristic applications, unresolved issues, and possible future directions.

56 Important unresolved issues are addressed, including the mechanism

57 Unresolved issues are also examined to shed light on new

58 s to clinical trials, many new and presently unresolved issues are coming into focus.

59 However, several unresolved issues are difficult to address using current

60 A number of unresolved issues are outlined and discussed, including

61 These unresolved issues are risk prediction models to identify

62 diagnosis for the clinician and to identify unresolved issues as a stimulus to future work.

63 these, heme dissociation remains a critical unresolved issue, as it leads to toxicity and compromise

64 plexity and diverse functionality remains an unresolved issue at the interface between living and non

65 There remain, however, many unresolved issues before such therapy can become a part

66 We also provide our perspective on unresolved issues, both conceptual and technical, that w

67 Here, we show that these unresolved issues can be explained through analysis of t

68 evels, and to discuss current controversies, unresolved issues, challenges, and future directions.

69 One unresolved issue concerning cecropins and other antibiot

70 nitrogenase remains enigmatic, with a major unresolved issue concerning how inhibitors and substrate

71 A key unresolved issue concerning SOC function is their spatia

72 Finally, we point to unresolved issues concerning the integrated function of

73 allowed us to address several important, yet unresolved, issues concerning the biological activity of

74 An unresolved issue concerns the consequences for visuomoto

75 Two unresolved issues could better illuminate the mechanisti

76 the development of socioemotional skills are unresolved issues destined to attract future research.

77 m these field synopses and discuss remaining unresolved issues -- especially in the light of evidence

78 elation to the martensitic phase is still an unresolved issue, even though it is critical to the unde

79 detection of tumorous tissue is an important unresolved issue for cancer surgery.

80 tion of nitroaromatic explosives has been an unresolved issue for over a decade.

81 s alleviated by a hearing device is a major, unresolved issue for rehabilitation.

82 ne pyrimidine dimers (CPDs), remains the key unresolved issue for the origins of RNA and DNA on Earth

83 driven interactions have emerged as exciting unresolved issues for understanding gene regulation.

84 face contamination has long been a critical, unresolved issue, given graphene's two-dimensionality.

85 Another unresolved issue has been the genesis of 'restricted' an

86 tes and involve some distinct components, an unresolved issue has been whether multiple pathways conv

87 i is the prototype of such pathways, several unresolved issues have accumulated over the years.

88 Unfortunately, several unresolved issues have seriously hampered quantitative d

89 One important unresolved issue, however, is the mechanism through whic

90 An unresolved issue, however, is the role of stable inherit

91 An important, unresolved issue, however, is whether this integrin can

92 A major unresolved issue in biology is why phenotypic and geneti

93 An unresolved issue in chronic lymphocytic leukemia (CLL) i

94 An unresolved issue in contemporary biomedicine is the over

95 An unresolved issue in cortical development concerns the re

96 osses the blood-brain barrier (BBB) is a key unresolved issue in cryptococcosis.

97 A key unresolved issue in cuprates is the relationship between

98 e committing resources to reproduction is an unresolved issue in developmental biology.

99 neous natural environments remains a largely unresolved issue in ecology.

100 A central unresolved issue in evolutionary biology is how metaboli

101 herbivore dietary specialization has been an unresolved issue in evolutionary ecology.

102 Poor flow patency is an unresolved issue in grafts, particularly those with diam

103 One unresolved issue in gut immunity is how mucosal T lympho

104 One unresolved issue in immune tolerance is what prevents se

105 An important unresolved issue in microbial secondary metabolite produ

106 An important, unresolved issue in mononegavirus biology is whether or

107 An unresolved issue in ocean and climate sciences is whethe

108 An unresolved issue in ocean science is the discrepancy bet

109 However, one key unresolved issue in paleoclimate modeling is reproducing

110 An unresolved issue in preventive cardiology is whether the

111 An unresolved issue in structural biology concerns the rela

112 es an enduring yet dynamic memory remains an unresolved issue in studies of memory.

113 lfur clusters as they exist in vivo, a major unresolved issue in studies of Wbl proteins.

114 A major unresolved issue in the cloning of mammals by somatic ce

115 for their expression have long been a major unresolved issue in the field of epigenetics.

116 TCs) and separated charges (SCs) is still an unresolved issue in the field of organic photovoltaics.

117 A major unresolved issue in the field of secretory granule bioge

118 An unresolved issue in the field of T helper (Th) cell deve

119 heparin-induced thrombocytopenia remains an unresolved issue in the ICU leading to the unjustified s

120 's disease (PD) is the single most important unresolved issue in the management of this disorder.

121 A major unresolved issue in the pathogenesis of HIVAN is whether

122 An unresolved issue in the vegetation ecology of the Indian

123 ons perturbed by TorsinA[DeltaE] are a major unresolved issue in understanding the pathophysiology of

124 There are many unresolved issues in adults and children with PN depende

125 Progress on several unresolved issues in cancer epigenetics will benefit fro

126 There are a number of unresolved issues in EoE, including phenotypes, optimal

127 slands' can improve our understanding of two unresolved issues in evolutionary genetics: the likely l

128 nctional dynamics, one of the most important unresolved issues in protein science.

129 erism of ligands and receptors is one of the unresolved issues in structure-based prediction of bindi

130 y activity in the cortex are among the major unresolved issues in systems neurobiology.

131 system allows for the addressing of central unresolved issues in the B-AR-Ca(V)1.2 cascade and will

132 Unresolved issues in the field are outlined.

133 Key unresolved issues in the field of emotional memory inclu

134 nderstanding of STING and highlight the many unresolved issues in the field.

135 We conclude with a discussion of several unresolved issues in the field.

136 To investigate two unresolved issues in the initiation of signaling, the ro

137 One of the central, unresolved issues in the pathogenesis of acute pancreati

138 umans and animals addressing these and other unresolved issues in the physiology of obesity.

139 t results and discuss some controversies and unresolved issues in this field.

140 idered carefully, especially with respect to unresolved issues in tumor biology.

141 This review highlights recent progress and unresolved issues in understanding the function and regu

142 ent one of the most fundamental, yet largely unresolved, issues in evolutionary biology.

143 However, many unresolved issues, in particular the possibility of othe

144 Unresolved issues include a means for rapid identificati

145 Unresolved issues include optimal patient selection crit

146 Unresolved issues include optimisation of vaccination st

147 Unresolved issues include psychology's neglect of levels

148 However, unresolved issues include the astonishing complexity of

149 Unresolved issues include the most critical groups to va

150 The many unresolved issues include the role of the amino-terminal

151 Unresolved issues include the timing, content, and scope

152 Unresolved issues include to what degree, when, and how

153 In parallel, further studies will address unresolved issues including durability of blood pressure

154 We focus on unresolved issues including phenotypic and genetic heter

155 Despite these results, there are many unresolved issues, including no defined standard techniq

156 There are several unresolved issues, including the following.

157 An unresolved issue is how ASMase residing within lysosomes

158 One unresolved issue is how infection or vaccination with se

159 A key unresolved issue is how ions gain access to the pore, be

160 An important and unresolved issue is how T cells discriminate between pot

161 A central unresolved issue is how the Cdc45-MCM-GINS helicase is l

162 A key unresolved issue is how the highly complex adaptor-clath

163 However, a major unresolved issue is how the individual component traits

164 A major unresolved issue is how these different populations of T

165 A major unresolved issue is how transcription factors find their

166 An unresolved issue is the degree to which the fate of NCCs

167 One unresolved issue is the duration and significance of the

168 An important unresolved issue is the extent to which incompatibility

169 One unresolved issue is the extent to which the loop bundle

170 A crucial unresolved issue is the extent to which this organizatio

171 A major unresolved issue is the mechanism by which the tyrosyl r

172 A major unresolved issue is the relative timing of CAI and chond

173 A major unresolved issue is the role of Cdc20 autoubiquitination

174 A major unresolved issue is the type strain of N. asteroides, as

175 The most important unresolved issue is understanding the evolutionary cause

176 An important unresolved issue is whether and to what extent LTP and L

177 A key unresolved issue is whether astrocyte [Ca(2+)](i) elevat

178 An important unresolved issue is whether covert attention can also sp

179 An unresolved issue is whether power-law scaling on differe

180 One key unresolved issue is whether prefrontal cortical outputs

181 However, an important but unresolved issue is whether this forebrain structure als

182 An important but unresolved issue is why this occurs.

183 One of the most crucial unresolved issues is identifying the symmetry of the sup

184 An important unresolved issue of AIDS pathogenesis is the mechanism o

185 This study investigated the unresolved issue of antigen-dependency and antigen-speci

186 ct and indirect mechanisms contribute to the unresolved issue of CD4(+) T-cell depletion that results

187 A central, yet unresolved issue of HIV disease is the mechanism for thi

188 Here we address the unresolved issue of how many Hox target genes are suffic

189 er or not bacterial species exist remains an unresolved issue of paramount theoretical as well as pra

190 offer significant advantages for addressing unresolved issues of neuronal development.

191 ific deletion of SCL and CXCL12, we focus on unresolved issues on HSC niches, framed around some very

192 With regard to earlier unresolved issues on the macaque evolution, the topology

193 Unresolved issues on the role of RNA silencing in virus-

194 ceptible to Michael addition of thiols, with unresolved issues on the site of adduction and precise s

195 to the interchain hopping energy remains an unresolved issue, one that is central to many organic an

196 To discuss unresolved issues pertaining to aetiology and diagnosis

197 affects microvascular obstruction in SCD, an unresolved issue pivotal to understanding its clinical e

198 The last section summarizes some critical unresolved issues, possible challenges/obstacles and als

199 An unresolved issue regarding cortical mechanisms of dip-li

200 nd mesenteric vein thrombosis, but there are unresolved issues regarding monitoring with both the ant

201 One of the key unresolved issues regarding proton pumping in cytochrome

202 Two unresolved issues regarding the identification and chara

203 Here, we review recent findings and unresolved issues regarding the neural mechanisms of bod

204 In this study, we address two previously unresolved issues regarding the requirement for perforin

205 will be placed in the context of previously unresolved issues related to BDNF biology, as well as ho

206 Three unresolved issues related to cortical activity in subjec

207 The unresolved issues related to long-range electron transpo

208 ned studies are necessary to address several unresolved issues related to PFO stroke and PFO migraine

209 Last, unresolved issues related to the duration of use of para

210 However, unresolved issues related to the spatial, spectral, and

211 A major unresolved issue relating to internal climate dynamics i

212 Many unresolved issues remain, including the vasoactive media

213 An unresolved issue remains the rapid loss of the native co

214 Moreover, some of the unresolved issues revolving around the suboptimal positi

215 f nuclear import and export as well as major unresolved issues such as how directionality is conferre

216 stent embodied energy calculation, there are unresolved issues, such as an overdependence on price da

217 An unresolved issue surrounding self-antigens as immunother

218 ponses to PI3K pathway inhibitors to address unresolved issues surrounding the efficacy and tolerabil

219 There are a number of unresolved issues surrounding this illness, which are th

220 rome c peroxidase has been an intriguing but unresolved issue that impacts our understanding of the r

221 The traceability of olive oil is an unresolved issue that remains a challenge.

222 Here, we define the previously unresolved issues that are now better understood for the

223 controls pluripotent identity and highlight unresolved issues that arise from these studies.

224 on of asthma clinical remission and identify unresolved issues that deserve further investigation and

225 igin-free (CD-AOF) media and supplements are unresolved issues that hamper the clinical applicability

226 in the immune system, as well as some of the unresolved issues that remain on the road to eventually

227 However, there are many unresolved issues that surround whether or not imaging w

228 To address these unresolved issues, the American Society of Hematology es

229 in viability assessment is complex with many unresolved issues to be considered in the design and imp

230 Here we addressed these unresolved issues using simultaneous recordings from mul

231 on current understanding and a discussion of unresolved issues, we propose a molecular model for init

232 However, it remains an unresolved issue whether beat-to-beat alternations in in

233 However, it remained an unresolved issue whether differences in Aux/IAA turnover

234 rrent sensor technologies still exhibit some unresolved issues which hampers their direct application

235 due to HIV-1 infection remains a pivotal but unresolved issue with important implications for vaccine

236 To address unresolved issues with respect to the evolutionary relat