ライフサイエンスコーパス: unspecific

1 degradation process generally believed to be unspecific.

2 ly been criticized as possibly too broad and unspecific.

3 but are highly insensitive and in many cases unspecific.

4 ascular procedures, thyroidectomy, and other unspecific abdominal procedures.

5 Fifteen patients presenting with unspecific abdominal symptoms in which food allergy was

6 we could describe LA as the link between the unspecific action of general anesthetics and toxins with

7 tion of how complex object use compared with unspecific actions are processed and especially how such

8 he efficient antigen presentation by antigen-unspecific activated B cells was correlated with a down-

9 We have discovered a new pathway involved in unspecific Ad5 sequestration and degradation.

10 ty manipulation, providing evidence for item-unspecific adjustment of early distractor processing to

11 ing media changes (water to NaCl solutions), unspecific adsorption of bovine serum albumin (BSA), or

12 layer coated slides, revealing low levels of unspecific adsorption of DNA on S-layer based immobiliza

13 homogeneous and not too compact SAM in which unspecific adsorption of the capture probe would be prev

14 washing, eliminating inaccuracies caused by unspecific adsorption to hydrophobic surfaces.

15 for each sample and the reagent, so that any unspecific adsorption to the polymer surfaces does not a

16 choose to monitor bovine serum albumin (BSA) unspecific adsorption, which has been often employed in

17 ly of molecular chaperones that suppress the unspecific aggregation of miscellaneous proteins.

18 provides an environment that maintains both unspecific and Ag-specific CD8+ T cells with restricted

19 t further enzymes of this pathway are rather unspecific and catalyze more than one reaction, leading

20 from postexposure vaccination may be antigen unspecific and due rather to an early activation of the

21 inical presentation of pulmonary embolism is unspecific and easily mistaken for other common medical

22 Today, therapy is still unspecific and far from interfering with the cause(s) of

23 A surplus of any of the subunits may trigger unspecific and harmful protein interactions and has to b

24 n the current formulations, they are species-unspecific and have very little particularly human about

25 se results suggest the concurrence of shared unspecific and host-related plant responses to CelC2 dur

26 difficult to suspect because it is rare with unspecific and long-term symptoms; it can be lethal if n

27 a preference for the minor groove and weaker unspecific and more salt-dependent binding than to the G

28 volunteers (n=30) were stimulated with both unspecific and pathogen-specific antigens.

29 thy volunteers (n = 30) were stimulated with unspecific and pathogen-specific antigens.

30 , Th2, and Th17 immunity in response to both unspecific and pathogen-specific stimulations.

31 , Th2, and Th17 immunity in response to both unspecific and pathogen-specific stimulations.

32 escentic glomerulonephritis (GN) consists of unspecific and potentially toxic immunosuppression.

33 dmitted to ICU were less likely to have both unspecific and specific T-cell responses in IGRA.

34 us luteus as substrate showing that both the unspecific and the covalent lysozyme immobilization enha

35 Its treatment includes unspecific and toxic agents; therefore, the identificati

36 oluble Wnt ligands, but their cytonemes form unspecific and unstable interactions with localized Wnt

37 ites, followed by a linear shift typical for unspecific and unstable vapor uptake.

38 ve treatments target T cells, are relatively unspecific, and result in profound immunosuppression tha

39 However, unspecific antigen recognition, poor molecular probe ads

40 particles loaded with RNA coding for tumour-unspecific antigens.

41 edictive performance as opposed to behaviour-unspecific approaches.

42 Our data suggest that, even if unspecific as the other lesions conventionally associate

43 mechanisms are often imperfect in preventing unspecific associations; different sensory stimuli can b

44 ns between orientation-selective neurons are unspecific at the time of eye opening, and become to som

45 hanced functional connectivity to a modality-unspecific attention network.

46 tic cell-surface repulsion uncovers weak and unspecific attractive forces in the bilayer that bring t

47 In unspecific axonal learning, a synapse's modification giv

48 vating stimuli, both lymphoid DC and antigen-unspecific B cells present to a similar extent class II-

49 ntigen-presenting cells, the role of antigen-unspecific B lymphocytes in antigen presentation and T-l

50 at when they are properly activated, antigen-unspecific B-lymphocytes can present exogenous antigens

51 specific connectivity must remain stable for unspecific background activity.

52 s in image analysis, such as limited signal, unspecific background, empirically set thresholds, image

53 Cointernalization is not unspecific, because ligand-driven KIT internalization is

54 2-overexpressing cancer cells, however, some unspecific binding also occurred.

55 rrays requires sufficient probe density, low unspecific binding and high interaction efficiency with

56 cal microscopy underlined the comparably low unspecific binding and the applicability for studying M(

57 non-reactive, hydrophilic support lowers the unspecific binding and the number of handling steps requ

58 n is needed to minimize the percentage of A9 unspecific binding and to increase the binding affinity

59 a high binding efficiency, while showing low unspecific binding during the following assay.

60 et accessibility of the liposomes as well as unspecific binding need further consideration.

61 by a new preanalytical protocol that reduced unspecific binding of serum components to the cellulose-

62 While certain antibodies displayed unspecific binding to bare minerals, we validated that p

63 bly, the maleimide beads showed undetectable unspecific binding to endogenous immunoglobulin G (IgGs)

64 t tetramer-stabilizing ligands we found that unspecific binding to plasma components might significan

65 drophilic cellulose coated supports with low unspecific binding, high selectivity and appropriate sen

66 orthosteric antagonist atropine to determine unspecific binding, proved that the monomeric and the di

67 For the definition of unspecific binding, the A1AR selective antagonist 8-cycl

68 lent immobilization route as compared to the unspecific binding.

69 notypes 2a/c, 2b, and 3 and did not show any unspecific binding.

70 cations in binding studies and assessment of unspecific binding.

71 factor binding mainly alters association and unspecific binding.

72 small cross frequency shifts due to remnant unspecific binding.

73 h are subsequently blocked with BSA to avoid unspecific binding.

74 Unspecific bone uptake (UBU) related to [(18)F]PSMA-1007

75 ever, recent reports indicate a high rate of unspecific bone uptake (UBU) with (18)F-PSMA-1007, which

76 -specific membrane antigen (PSMA) PET scans, unspecific bone uptake has been described.

77 nternal validity of findings according to an unspecific bruxism diagnosis.

78 a further 4 patients, initial histology was unspecific, but during the course of the disease all pat

79 le the existing models are largely condition unspecific by employing a single biomass reaction, we pr

80 fic TCR clonotypes from TCRs associated with unspecific bystander activation by comparing responses t

81 sue, Barnstorf et al. (2019) show that virus-unspecific bystander memory T cells are highly affected

82 Incidence and mortality for sex-unspecific cancers are higher among men, a fact that is

83 nuclear/cytoplasmic YAP shuttling is not an unspecific cellular response but relies on the sequentia

84 was accompanied by the largest separation of unspecific changes in their surface properties.

85 o ATP, which induces the yeast mitochondrial unspecific channel, and to alamethicin, a membrane-disru

86 h salt concentrations and is not based on an unspecific charge-dependent interaction of the relativel

87 It is often misdiagnosed due to its unspecific clinical and radiologic appearance.

88 For a disease with unspecific clinical findings, and the possibility of a s

89 ity of CA1 cells, with location specific and unspecific components.

90 es, targeted and highly selective as well as unspecific cross-linking capability, the attachment of t

91 zinone 1, is highly selective, exhibits less unspecific cytotoxicity than the previously reported Del

92 nserved bacterial ClpP protease, causing the unspecific degradation of essential cellular housekeepin

93 ked in transcriptome datasets or regarded as unspecific degradation products.

94 bly neocortical inhibition in general, is an unspecific, densely homogenous matrix covering all nearb

95 on is readily explained by the assumption of unspecific depletable resources.

96 ons and antibody cross-reactivity results in unspecific detection that cannot be distinguished from b

97 ong one specific dimension, while the other, unspecific dimension was defined solely by perceptual si

98 ing of >70 potential off-targets revealed no unspecific editing.

99 e mos10/mos10 phenotype is unlikely to be an unspecific effect of disruption of endocytosis or vacuol

100 ibitory tDCS over the vertex, to exclude any unspecific effect of tDCS.

101 Unspecific effects due to global shifts of attention or

102 Recognition of the possible unspecific effects elicited by RNAi vectors is important

103 by a true antisense mechanism without overt unspecific effects on cell growth and splicing of other

104 artificial ligand to avoid off-target and/or unspecific effects.

105 ticed that sequences within L4440 may elicit unspecific effects.

106 prodromes, initial nonshockable rhythm, and unspecific electrocardiogram repolarization abnormalitie

107 ng the reduced FMN cofactor from engaging in unspecific electron transfer reaction.

108 43 times faster than did MtAhpE-SH with the unspecific electrophile 4,4'-dithiodipyridine, a disulfi

109 In the past, unspecific elimination of ROS by use of low molecular ma

110 in predicting pain, general anticipation or unspecific emotional and autonomic arousal.

111 henotypes uncovered by the administration of unspecific exogenous dsRNA.

112 In contrast, unspecific expanded T cells were more clonally restricte

113 with lower FA, suggesting lower FD underlie unspecific FA reductions.

114 level visual features present in inverted or unspecific facial identities are not sufficient to produ

115 sis, a p53-regulated form of cell death with unspecific features previously classified as paraptosis.

116 1 cases, multiphase PMCT angiography showed "unspecific filling defects," which were not reported by

117 red-flag symptoms and the specific and many unspecific findings that can be identified in additional

118 inhibitory plasticity rule, synapses become unspecific (flat), anticorrelated to, or correlated with

119 w detection rate of conventional imaging and unspecific fluctuations in prostate-specific antigen can

120 allenge due to fragmentation difficulties or unspecific fragment ion information.

121 The results revealed an unspecific frowning response as well as activity over th

122 me it also can act indirectly, leading to an unspecific gain setting.

123 dicates that the lateral network acts via an unspecific gain-setting mechanism, scaling the output of

124 found in STARNET than in tissue- and disease-unspecific gene-tissue expression studies, indicating sh

125 lling algorithms in combination with species-unspecific genes.

126 thway has been mainly investigated by rather unspecific genetic manipulations of beta-catenin that yi

127 Methyglyoxal is commonly used for the unspecific glycation of Abeta1-42, which results in a co

128 a token action I am about to perform - and "unspecific goals" - the end-state of an action-type (wit

129 tion of lignin is, however, majorly based on unspecific gravimetric analysis after sulfuric acid hydr

130 to the same extent by the Sec complex and an unspecific GroEL trap, indicating that release occurs sp

131 ern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-targe

132 traditional filtering strategy of discarding unspecific guides from the analysis.

133 compared behaviour-specific versus behaviour-unspecific habitat selection in relation to terrain feat

134 n the soil metagenome including specific and unspecific halogenases as well as metabolic and cometabo

135 (2) and supply the oxidant to the engineered unspecific heme-thiolate peroxygenase PaDa-I.

136 are antigen-specific skin-homing T cells or unspecific heterogeneous bystander cells.

137 ell as a random sample of 14,400 visits with unspecific ICD-10 codes (R and Z codes), were screened m

138 as present in 0.028% of the random sample of unspecific ICD-10 codes.

139 injury compared with control treatment with unspecific IgG.

140 anagement of patients by avoiding the use of unspecific imaging methodologies and reducing unnecessar

141 washed-out lysozyme (factor 1.7-3.4) for the unspecific immobilization route when compared to the cov

142 covalent immobilization route as compared to unspecific immobilization.

143 , we selected beetles for either specific or unspecific immune priming toward the bacteria Pseudomona

144 Taken together, IgD-binding NTHi leads to an unspecific immune response and may support the bacteria

145 ith the adrenal medulla via mediators of the unspecific immune system

146 to lack adaptive immunity and be relatively unspecific in their interactions with pathogens.

147 lectroconvulsive therapy-both effective, yet unspecific in their modes of action.

148 osative one because ROS are too reactive and unspecific in their reactions for regulatory purposes an

149 tive treatment with infliximab reduces early unspecific inflammatory responses and complements immuno

150 processing, including stimulus-specific and unspecific information.

151 e selected arm was associated with spatially-unspecific inhibition.

152 y poor biocompatibility and bioavailability, unspecific interactions and insufficient local concentra

153 protein concentrations in living cells favor unspecific interactions between partially folded protein

154 orona is, however, a reduction in the purely unspecific interactions between the bare material and th

155 istent contacts provide specificity, whereas unspecific interactions boost affinity.

156 molecular dynamics simulations predict that unspecific interactions slow down microsecond- to millis

157 For epicatechin, unspecific interactions were found only at higher protei

158 use it prevents aggregation while minimizing unspecific interactions with proteins.

159 ties of AvantCap: (i) reduced propensity for unspecific interactions, (ii) involvement in alternative

160 biocompatibility of such materials, minimize unspecific interactions, improve biofunctionalization ef

161 Ethanolamine capping was applied to avoid unspecific interactions.

162 mportance of both cell assemblies and dense, unspecific interneuron connectivity in explaining our ex

163 e behavioral therapy (LLD-CBT) or supportive unspecific intervention (SUI).

164 While Gd(3+) depends on unspecific ion-pair interactions with anionic components

165 s contained in the two types of oil by using unspecific IR spectral information.

166 HPLC/(71)Ga species-unspecific isotope dilution ((71)Ga-SUID) ICP-MS was sub

167 In species-unspecific isotope dilution analysis, using postcolumn I

168 enoproteins and selenometabolites by species unspecific isotopic dilution ICP-MS, with unequivocal id

169 cence microscopy and a high DOL with minimal unspecific labeling is beneficial for fluorescence micro

170 oral dementia and Parkinson's disease, while unspecific learning deficits (across social and non-soci

171 mporal stimulus features or reflect stimulus-unspecific, less-time specific processing aspects.

172 gest that the sensory information comes from unspecific load signals sensed by cuticle mechanorecepto

173 sions most frequently observed were ganglia, unspecific lymph node, and bone lesions, at a rate of 43

174 % with (68)Ga-PSMA-11 for ganglia, bone, and unspecific lymph nodes, respectively).

175 sp14 methylated RNA substrates in a sequence-unspecific manner.

176 atase PhoB or by any other phosphatase in an unspecific manner.

177 was coupled to bitumen biodegradation in an unspecific manner.

178 that enlarged size has been identified as an unspecific marker for psychiatric illness, including sch

179 erations with lime juices due to potentially unspecific markers.

180 We categorize these as either (i) disease unspecific markers; (ii) markers of specific pathways th

181 Many methods of cell transfection rely on unspecific means to increase the transport of genetic ma

182 tisfactory and propose to replace it with an unspecific mechanism capturing approximate magnitudes fr

183 rimotor predictions and is instead due to an unspecific mechanism.

184 1007 exhibits a significantly higher rate of unspecific medullary spots (P = 0.0006).

185 LA as the middle part of a continuum between unspecific membrane-mediated activity on one end and hig

186 hts the advantages of combining specific and unspecific methods for characterizing NM surface chemist

187 tor information preserved in ichnofossils or unspecific modelling of locomotor dynamics.

188 traditional view of the outer membrane as an unspecific molecular sieve and indicate a higher degree

189 On the other hand, if one invokes unspecific neurotransmitter adsorption to the bilayer-a

190 of other diseases, 12 (85.7%) showed various unspecific nonerosive or erosive mucosal lesions within

191 This unspecific off-target activity shows that Cas9-BE3 can t

192 To mimic unspecific or allergen-specific ICs, plates were coated

193 bove the background level and categorized as unspecific or nonmalignant and grouped into degenerative

194 quality while dissecting the consequences of unspecific organ injury and immunosuppression on T-cell

195 manipulating circuit activity in humans and unspecific paradigms for modeling social behaviors in ro

196 s characterized using allelic (specific- and unspecific-parent TRD) and genotypic parameterizations (

197 usly considered a polymicrobial community of unspecific pathogenicity, is recognized as microbial bio

198 ue in phage display, namely the selection of unspecific peptides.

199 normal intracranial pressure, and MRI showed unspecific periventricular signal changes with T1 hyperi

200 Using the Unspecific Peroxygenase (UPO) from Agrocybe aegerita (Aa

201 one of these biocatalysts, which is known as unspecific peroxygenase (UPO).

202 In combination with an unspecific peroxygenase from Agrocybe aegerita, green li

203 A lyophilized preparation of an unspecific peroxygenase variant from Agrocybe aegerita (

204 In this study, we demonstrate that Unspecific Peroxygenases (UPOs) catalyse the biocatalyti

205 (H(2)O(2)) is essential for the stability of unspecific peroxygenases, which are deemed ideal biocata

206 se results indicated that Rv1698 provides an unspecific pore that can partially substitute for MspA.

207 sulfur in biological molecules via a species-unspecific postcolumn isotope dilution (online ID) appro

208 ation acting in cortical inputs and stimulus-unspecific postsynaptic adaptation.

209 Timely diagnosis can be challenging owing to unspecific presentation and questionable performance of

210 equent use of indirect proliferation assays, unspecific probes, or bulk analyses leads too often to m

211 olled access to the active sites of a highly unspecific protease.

212 The use of unspecific proteases such as Pronase can largely overcom

213 ization protocol that allows minimization of unspecific protein adsorption onto cantilevers.

214 The unspecific quality of these signals limits the possible

215 ion of mispaired TCR dimers and decreased or unspecific reactivity.

216 protochlorophyll or PChlide reduction by an unspecific reductase or by a ChlB/ChlN complex could acc

217 n differentiate between opioid analgesia and unspecific reductions in pain such as habituation.

218 data and showed that there is not a general/unspecific repressing function of mH2A1 or mH2A2 associa

219 Clinical manifestations are often unspecific, resulting in a challenging diagnostic work-u

220 We propose that the protein is an unspecific scavenger of flavin compounds and may serve a

221 g metabolization, short serum half-life, and unspecific side effects.

222 Steric hindrance (SH) suppresses unspecific signal and generates a signal-on amplificatio

223 The unspecific signal due to the low (16)O abundance in the

224 ductometric (bio)sensors, which specific and unspecific signals are directed in the same way (resista

225 These unspecific signals might result from common variants of

226 of time in the absence of glial pathology or unspecific signs of neurodegeneration.SIGNIFICANCE STATE

227 This is reflected by unspecific somatic symptoms and the predominance of the

228 Our findings suggest why Cas12j unleashes unspecific ssDNA degradation after activation.

229 spectrometry (MS) can use certified species-unspecific standards to validate shotgun or liquid chrom

230 The function of PD-L1 on T cells after unspecific stimulation was dependent on both cell type a

231 After the initial use of unspecific stimuli, scientists have recently put a lot o

232 ion of this correlation is that GBOs reflect unspecific stimulus-triggered attentional processing.

233 The unspecific substrate requirements and minimal sample dis

234 s and molecular orbital theory, that element-unspecific symmetry-breaking rather than element-specifi

235 nces in sarcoid patients with no symptoms or unspecific symptoms and preserved left ventricular eject

236 ed as an alternative explanation for complex unspecific symptoms during the COVID-19 pandemic.

237 ic joint infections are often accompanied by unspecific symptoms, false-negative cultures or nonspeci

238 in older and smoking subjects complaining of unspecific symptoms, such as dyspnea and fatigue.

239 upon allergen contact and present often with unspecific symptoms.

240 e and severe cardiovascular emergencies with unspecific symptoms.

241 To monitor and control the level of unspecific T-cell activation, we developed a sensitive a

242 scue the penumbra have failed, likely due to unspecific targeting and persistent excitotoxicity, whic

243 tion of both sequence-specific knowledge and unspecific task ability.

244 ed hundreds of Mtb-specific TCRs, as well as unspecific TCRs, and characterized their phenotype in ea

245 clinical practice as a highly sensitive, but unspecific tool to quantify active brain pathology.

246 g enzyme inhibitors that are symptomatic and unspecific toward DMD disease.

247 ing to an increased inflammatory reaction to unspecific triggers.

248 A machine-learning approach controlling for unspecific UCMS effects identified transcriptomic predic

249 nvestigate three patients of both sexes with unspecific unilateral medial temporal lobe (MTL) damage,

250 at account for PPIs but the PPIs are context-unspecific, we recently integrated the two data types in