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1 erritin genes AtFER1, AtFER3, and AtFER4 are up-regulated.
2 , translation of intron-containing mRNAs was up-regulated.
3 imary virulence mechanism-were significantly up-regulated.
4 fections, whereas immune response genes were up-regulated.
5 ling immune responses including IFNgamma are up-regulated.
6 differentially expressed inactive genes are up-regulated.
7 assrA strain, the light organ differentially up-regulated 10 genes, including several encoding height
8 dothelial cells' secretome, 46 proteins were up-regulated: 45 were host secreted proteins (including
9 These data suggest that CTBs from PAS cases up-regulate a cancer-like proinvasion mechanism, suggest
10 ive signals, we find that follicular B cells up-regulate a wide array of UPR-affiliated genes before
11 at selective loss of astroglial FMRP in vivo up-regulates a brain-enriched miRNA, miR-128-3p, in mous
13 e cytomegalovirus (MCMV) infection, NK cells up-regulated Adrb2 (which encodes the beta2-adrenergic r
16 reveal that ROBO2 expression in podocytes is up-regulated after glomerular injury because its express
17 factors (TNF-alpha, IL-1beta, and IL-6) and up-regulate an anti-inflammatory factor (IL-10) in infla
18 ing cell stress and nutrient deprivation can up-regulate and activate DinB/pol IV, the bacterial orth
22 tial metabolites were screened including 112 up-regulated and 175 down-regulated and they belong to l
23 1 differentially expressed genes (DEGs), 566 up-regulated and 235 down-regulated in the genotypes wit
26 icantly altered in the cochlea on day 1 (40% up-regulated and 60% down-regulated), whereas only 49 DE
28 ns (FATP) and FA binding proteins (FABP) are up-regulated and fetal plasma FA concentrations are decr
29 ochondrial molecular chaperone that is often up-regulated and mislocalized in tumors with abnormal ac
30 , the growth factor gene Igf2 was aberrantly up-regulated, and ectopic Igf2 overexpression was suffic
32 synthase and chorismate synthase, were also up-regulated, as well as indole-3-glycerol phosphate syn
35 we showed that centromeric SET/TAF1 on Sgo2 up-regulates Aurora B kinase activity via PP2A inhibitio
37 r IL-21, is required via STAT3 activation to up-regulate Blimp-1 and promote Th2 cell development.
40 , the results revealed that date palm's leaf up-regulates both cellular and phytohormonal determinant
44 ins that are highly expressed in midguts and up-regulated by blood meals were chosen for analysis.
49 work factor 1 (CYR61) as a chemokine that is up-regulated by hepatocytes during liver injury but is e
51 675-5p (miR675-5p) as the miRNA most highly up-regulated by incubation of colorectal cancer cells wi
52 In the microsphere model, PD-1 ligands are up-regulated by infection, and the PD-1/PD-L1 axis is fu
53 Conversely, SOD4 expression was specifically up-regulated by iron (Fe) starvation and controlled by t
54 paralogs, caspase-10 (also transcriptionally up-regulated by p53), induced apoptosis in Nutlin-3A-tre
55 e, the miRNAs found to be most significantly up-regulated by quantitative reverse transcription polym
56 ike protein 2 (ANGPTL2), was confirmed to be up-regulated by quantitative RT-PCR and immunohistochemi
57 allei, was identified and its expression was up-regulated by ten-fold when B. pseudomallei was cultur
59 alpha (ERalpha) and that this association is up-regulated by treating the cells with estrogen (E2), d
60 are interconnected via intracellular Ca(2+) Up-regulated Ca(2+) levels lead to a remarkable alterati
62 Indeed, here we show that ETEC use LT to up-regulate carcinoembryonic antigenrelated cell adhesio
63 otomab-satetraxetan (Betalutin) was shown to up-regulate CD20 expression in different rituximab-sensi
65 functionality of candidate REs near Ryr2, an up-regulated chamber-enriched gene, and in Cacna1g, a do
66 kdown mice, reconstitution of FXR expression up-regulated cholesterol transport genes for its biliary
67 HSD11B1, VIP, and UBA6) were regulated by an up-regulated circRNA (circARID1A) via sponging a down-re
68 Glutamine-deficient pancreatic cancer cells up-regulate classic EMT regulator Slug, providing a link
69 lasks, mature hepatocyte markers were highly up-regulated compared with static organoid cultures, and
70 Interestingly Blimp1 inactivation results in up-regulated Csf1 expression and macrophage recruitment
71 ile with clinical samples and expresses SCCB-up-regulated CSPs at both the mRNA and protein levels.
72 and cytokine storm." AFB(1)-generated debris up-regulates cyclooxygenase-2 (COX-2), soluble epoxide h
74 f the DEGs associated with these terms, nine up-regulated DEGs and 32 down-regulated DEGs showed the
76 Here we show that aerobic exercise training up-regulates DICER in adipose tissue of mice and humans.
77 sults indicate that glucocorticoids directly up-regulate DPP4 expression and thereby induce migration
79 ether this same suite of protective genes is up-regulated during desiccation in even more distantly r
82 ntercellular adhesion molecule-1 (ICAM-1) is up-regulated during inflammation by several cell types.
86 -type MYB TF genes, GmMYB29A1 and GmMYB29A2, up-regulated during the times of peak glyceollin biosynt
87 pigenetically silenced, B2s become massively up-regulated during thermal and other types of stress.
88 ase, and other starch branching enzymes were up-regulated, either in their native tissues or in an ec
90 r high salt, a significant proportion of the up-regulated enzymes were associated with the Calvin-Ben
91 ve stress by increasing folding capacity and up-regulating ERAD components that remove non-native pro
92 mbination DNA-repair genes and concomitantly up-regulates error-prone polymerases in drug-tolerant (p
94 upon Rankl induction, osteoblast progenitors up-regulate expression of the chemokine ligand Cxcl9l.
95 retinal Cd40 mRNA translation and failed to up-regulate expression of the inflammatory marker nitric
96 macrophages with ERCs from DKO mouse livers up-regulated expression of the B cell-directed chemokine
99 evades antibiotics in bacterial biofilms by up-regulating expression of a symbiotic filamentous inov
102 LL-ASSOCIATED KINASE-LIKE21 (OsWAKL21.2), is up-regulated following treatment with either Xanthomonas
103 (4-[2-aminoethyl] benzene sulfonyl fluoride) up-regulated full-length Dicer, both in MM6 cells and in
104 andin E2) added to differentiating MM6 cells up-regulated full-length Dicer, through EP2/EP4 and cAMP
106 arnesoid X receptor (FXR) and epigenetically up-regulates FXR targets important for the regulation of
107 cogenic network were experimentally shown to up-regulate genes involved in cell-cycle and transcripti
109 th human LN gene expression revealed similar up-regulated genes as observed during the development of
112 duced by ER stress, was found among the most up-regulated genes in livers of PiZ mice that express AT
113 rson Correlation Coefficient|>= 0.9) with 91 up-regulated genes in the cell-cycle and Rho-GTPase path
115 ulated genes governing DNA damage repair and up-regulated genes involved in oxidative stress response
117 ructure and function were top-enriched among up-regulated genes, and anaerobic respiration, nitrate m
118 activates aldolase A and ERK signaling which up-regulates glycolysis and especially the non-oxidative
119 mitochondrial metabolism while concomitantly up-regulating glycolytic genes, whereas HIF-2alpha prima
121 ietin, which is elevated in anemic patients, up-regulates heparanase expression via the Janus kinase
122 sure to hypoxia + TBT, oysters substantially up-regulated HIF1-alpha and down-regulated Tbeta-4, alth
123 Finally, we observed that aneuploid cells up-regulate immune response genes and down-regulate gene
124 ity-modulating transcription factor (TF), is up-regulated in 2-KO cells and also physically binds to
125 rgic receptor ADRB2, are strongly (~20-fold) up-regulated in 2-KO cells, whereas other mRNAs, includi
126 phingomyelin (SM) species were significantly up-regulated in 5-FU-resistant cells in MALDI-TOF analys
129 Here we show p53 protein expression can be up-regulated in adipocytes by nutrient starvation withou
131 lated neu-associated kinase (HUNK) kinase is up-regulated in aggressive breast cancers and is thought
133 Chondroitin sulfate proteoglycans (CSPGs), up-regulated in and around the glial scar after mammalia
135 ified LGALS1 to be a GLI target gene that is up-regulated in both Gorlin tNES cells and SHH-subgroup
137 oxidant 1 copper chaperone (Atox1), which is up-regulated in breast cancer, is localized at the lamel
138 family member 1 (Them1) is transcriptionally up-regulated in brown adipose tissue upon exposure to th
140 Here, we report that purinosome formation is up-regulated in cells in response to a low-oxygen microe
144 modules: one populated by switch genes, all up-regulated in COPD cases and related to the regulation
145 well-recognized immune signature genes, all up-regulated in COPD cases; one where the GWAS genes AGE
149 VEGF)-C, a potent lymphangiogenic factor, is up-regulated in endometriotic cells and contributes to i
151 lectively, our results indicate that cGAS is up-regulated in HD and mediates inflammatory and autopha
154 sease, and FAP was previously reported to be up-regulated in human atherosclerotic plaques compared w
156 the histone-lysine methyltransferase G9a is up-regulated in human CCA and that G9a enhances CCA cell
157 e reported that miR-223-3p was significantly up-regulated in interphotoreceptor retinoid-binding prot
159 ycemic-hyperinsulinemic clamps, being highly up-regulated in liver and down-regulated in muscle and f
160 s high-titer hosts: Cell-growth pathways are up-regulated in low-titer genotypes, while membrane traf
161 vealed that myogenesis-associated genes were up-regulated in LSD2-KD cells under adipogenic induction
163 nd metabolic processes in macrophages and is up-regulated in macrophages in the context of obesity an
164 ane protein 3 (LAMP3), a gene that is highly up-regulated in many forms of cancer, including breast a
167 d with neutrophil/eosinophil activities were up-regulated in non-responders and, more importantly, om
168 However, some miRNAs were reported to be up-regulated in one subtype of a cancer but down-regulat
171 ein-coding genes that are down-regulated and up-regulated in pin1Delta cells, respectively, 77% and 1
172 rrelated with genes previously identified as up-regulated in primary prostate tumors from African Ame
173 the inhibitory surface glycoprotein CD5, are up-regulated in proportion to the strength of the self-p
175 roscopy imaging indicated that exocytosis is up-regulated in protrusions of Listeria in a manner that
176 stress-sensitive protein whose expression is up-regulated in response to cell stress to protect again
179 transcriptional target gene that is rapidly up-regulated in response to Nutlin-3A, an MDM2 inhibitor
180 ntify gene transcripts whose translation was up-regulated in response to the stress in a Gcn2-depende
182 protein geranylgeranyltransferase Pggt1b is up-regulated in single-positive thymocytes, and loss of
184 de exchange factor 3 (Rapgef3), was strongly up-regulated in the absence of LRRK2 and down-regulated
187 LINGO1 is a transmembrane protein that is up-regulated in the cerebellum of patients with Parkinso
191 t several key mediators of angiogenesis were up-regulated in the low-cell-dose microgel group, provid
193 ecreted peptides, named Eco1 and Eco2, being up-regulated in the response to both Curvibacter sp., th
196 patic SULT1E1 mRNA levels are constitutively up-regulated in type 1 diabetic Akita mice; CAR spontane
201 e innervation is necessary and sufficient to up-regulate ionotropic glutamate receptors from a pool o
205 Thus, we demonstrate the role of a S-phase up-regulated lncRNA in cell-cycle progression via modula
206 ciated with poorer prognosis, comprises five up-regulated lncRNAs significantly correlated (|Pearson
207 we show that SARS-CoV-2 infection strikingly up-regulates MARylating PARPs and induces the expression
210 conclusion, we uncover that glucose acutely up-regulates miR-199 family expression in beta-cells.
214 We demonstrate, for the first time, common up-regulated miRNAs that are associated with mitochondri
217 t the zinc finger transcription factor CASZ1 up-regulates MYOD signature genes and induces skeletal m
219 eural functions, TNBC has substantially more up-regulated neural genes than NTNBC, suggesting that TN
221 comiR-31, tumor suppressor target EGLN3, and up-regulated NF-kappaB-controlled inflammation signaling
222 e-1 and caspase-8 activation and principally up-regulates NF-kappaB and IL-1beta signaling in Pstpip2
224 se to B-Raf and MEK inhibition and was again up-regulated on drug resistance in vitro and in vivo.
225 an integral membrane protein that is highly up-regulated on the cell surface of several human cancer
226 We identified caspase-1 as a unique gene up-regulated only in pathogen-primed Th17 cells and disc
228 on nucleosomes, which solely coincides with up-regulated or uniquely presented poly(A) sites in hda6
230 ) In agreement with these observations, Akt3 up-regulates p53 in human cancer cell lines, and the exp
234 ng been fed the HFCF diet, WT mice displayed up-regulated peroxisome proliferator-activated receptor
235 andin E(2) accumulation in the intestine and up-regulates peroxisome proliferator-activated receptors
236 ism by which neuronal release of transmitter up-regulates postsynaptic expression of appropriate tran
238 cultures enhanced in vitro angiogenesis and up-regulated pro-angiogenic proteins expression after ox
239 porter LdNT3 is among the most substantially up-regulated proteins in purine-starved Leishmania donov
240 The depletion of PHF8 or PKCalpha greatly up-regulated PTEN expression, which could be rescued by
241 gulating the cell cycle and metabolism while up-regulating quiescence regulators Foxp1 and Fgf18.
244 ow that the GTPase-trafficking protein RAB1B up-regulates RIG-I pathway signaling and thereby promote
245 he Akt isoforms, Akt3 has also been shown to up-regulate ROS by promoting mitochondrial biogenesis.
246 based transfection assays, CHOP was found to up-regulate SERPINA1 cooperating with c-JUN, which was p
248 ng with c-JUN, which was previously shown to up-regulate SERPINA1, thus aggravating hepatic accumulat
249 A-seq experiments reveal that CASZ1 directly up-regulates skeletal muscle genes and represses non-mus
250 yb, a transcription factor for alphaSMA, and up-regulated small mother against decapentaplegic (SMAD)
253 tive sugar transporters, cbpC and cbpD, were up-regulated, suggesting their contribution to xylose tr
257 n of beta-1,4-galactan in root cell walls by up regulating the expression of GALACTAN SYNTHASE 1 (GAL
258 revealed that the two MS SNPs significantly up-regulate the associated OL enhancers, which we have n
260 e to SBM-based diets, yellow perch juveniles up-regulate the cholesterol biosynthesis pathway in orde
261 tion and accompanying surface TLR activation up-regulate the expression of 5'-tRNA half molecules in
262 of tight junctions that acts through EPAC to up-regulate the expression of claudin-5, to thus decreas
263 g substantive gene expression alterations to up-regulate the production of a wide variety of virulenc
264 ycolytic genes, whereas HIF-2alpha primarily up-regulated the angiogenesis transcriptional program.
265 experiencing stress from oncogene inhibition up-regulated the expression of Polkappa and shifted its
266 model show that in basal condition, butyrate up-regulated the expression of several biomarkers of gut
267 lly, weak p38alpha activation in fatty liver up-regulated the genes involved in fatty acid beta-oxida
268 IB, or both increased GBM cell migration and up-regulated the pro-migratory factors fatty acid-bindin
269 lective deletion of the miR-15a/16-1 cluster up-regulated the protein expression of pro-angiogenic fa
270 RAW 264.7 cells and human CD14(+) monocytes up-regulated the top six stroke-perturbed tRFs, and over
273 In the present study, we found that FBXL16 up-regulates the levels of proteins targeted by SCF-E3 l
274 erevisiae) responds to low cytosolic iron by up-regulating the expression of iron import genes; iron
275 A300 clone of MRSA, responds to avibactam by up-regulating the expression of the blaZ and pbp2a antib
277 activation of the YAP1 transcription factor, up-regulating the major pro-inflammatory factor, pro-IL-
278 optosis during later developmental stages by up-regulating the pro-apoptotic genes reaper and hid The
279 ny cancers alter their proline metabolism by up-regulating the proline cycle and proline biosynthesis
280 We show that TG2 increases glucose import by up-regulating the transcription of the glucose transport
281 Mechanistically, CIC-DUX4 transcriptionally up-regulates these negative regulators of MAPK to dampen
284 mTOR complex 1 (mTORC1) activity and thereby up-regulates transcription factors required for the form
285 yadenylation in Arabidopsis Poly(A) sites of up-regulated transcripts are closer to the histone acety
287 on followed by qRT-PCR validated the top six up-regulated tRFs in a separate cohort of stroke patient
288 1alpha1 (Col1alpha1), and fibronectin while up-regulating tumor necrosis factor alpha, interleukin-6
289 peroxidase and peroxidase were significantly up-regulated uniquely at 48 hpi and genes involved in zi
290 rotein import machinery that is specifically up-regulated upon mitoprotein-induced stress conditions.
291 Further, we show that Rcr1, but not Rcr2, is up-regulated via the calcineurin/Crz1 signaling pathway.
292 ially expressed genes (25 down-regulated, 41 up-regulated) were identified in heat-tolerant pigs comp
293 lly expressed genes (282 down-regulated, 759 up-regulated) were identified in the comparison between
294 membrane space protein Mix23 is considerably up-regulated when mitochondrial import is perturbed.
296 em and a flagellum apparatus are transiently up-regulated while endosymbionts infect putative stem ce
297 S, differentially expressed escape genes are up-regulated while the majority of inactive genes appear
298 at cancer-related genes on Chromosome 21 are up-regulated, while genome-wide cancer-related genes are