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1 2 increased HIF1A that in turn mediated EDN1 upregulation.
2 long-term thermosensory information for VIN3 upregulation.
3 ocytic cups, high phagosome content and CD68 upregulation.
4 inireplicon were sufficient for inducing HLA upregulation.
5 than RV-A without T-helper cell type 2 (Th2) upregulation.
6 ition of ROS blocked minority MOMP and Mcl-1 upregulation.
7 was investigated following its silencing or upregulation.
8 alleviate this repression leading to SPINK1 upregulation.
9 binding activities, were required for c-Myc upregulation.
10 tor talazoparib exhibited similar CSC marker upregulation.
11 ultiple tyrosine kinases and transcriptional upregulation.
12 ns, supporting poly(ADP-ribose) polymerase-1 upregulation.
13 The majority of changes were gene upregulations.
15 y augmented cold stress-triggered ASK1/p-p38 upregulation, adjunctive ASK1 inhibition alleviated IRI
19 f TEAD and Lats suppresses Wnt-uncoupled Myc upregulation and epithelial over-proliferation in Adenom
20 ring early lactation retards transcriptional upregulation and expression of KCC2, thereby delaying th
21 re the significant correlation between AEBP1 upregulation and increased EGFR expression in primary gl
23 TP53 mutations, which is associated with MYC upregulation and marked downregulation of MYC's negative
25 monocyte major histocompatibility complex II upregulation and persistent natural killer (NK) cell cyt
26 n cancer cells in attached conditions, SIRT3 upregulation and SIRT3-mediated oxidant scavenging are r
27 exhaustion is marked by inhibitory molecule upregulation and the development of TOX(+) and CD39(-)TC
28 ation, illustrated by CD86, CD83, and HLA-DR upregulation and their migration out of the epidermis.
29 o characterization of tumor-associated USP22 upregulation and unbiased interrogation of USP22-regulat
30 pes, including enhanced cell invasion, PD-L1 upregulation, and chemoresistance, were sustained in the
32 l-outcomes after ADT, possibly due to SPINK1 upregulation, and offers a strategy for adjuvant therapi
34 , chromatin stretching and ensuing DHFR gene upregulation by the in-plane mode are similar to those i
38 We confirmed the sequential order of Broad upregulation, Hindsight upregulation, and Cut downregula
40 was the only gene that exhibited consistent upregulation in AD brain transcriptomes from 3 independe
41 challenges of connecting repressors to gene upregulation in complex cell types with multiple possibl
42 In conclusion, this study confirms MIR34A upregulation in CRC tissues, and its rs2666433 (A/G) var
47 ember of the Bcl-2 family of proteins, whose upregulation in human cancers is associated with high tu
48 flammatory challenge led to robust eGFP-L10a upregulation in kidney, confirming Mac(TRAP) responsiven
53 ondrial influx Ca(2+) transporter genes, but upregulation in the genes related to mitochondrial Ca(2+
54 iR-1246 expression could play a role in ACE2 upregulation in the SAE of smokers; and 5) ACE2 is expre
56 diomyocyte nucleoplasmic [Ca(2+)] by IP(3)R1-upregulation involving miR-26a, leading to enhanced IP(3
57 s in many disease models, in which autophagy upregulation is able to reduce the levels of toxic prote
60 he long noncoding RNA ephemeron, whose rapid upregulation is crucial for the transition of ESCs into
61 with ivermectin suggesting that drug-induced upregulation is not the mechanism of Pgp-mediated ML res
63 show that inhibition of MTAP alongside SSAT upregulation is synergistic in androgen sensitive and ca
64 n plasticity: Ca(2+)-permeable AMPA receptor upregulation, L-type Ca(2+) channel activation, enhanced
66 hers, raising the possibility that autophagy upregulation may help to reduce levels of toxic protein
67 analysis of TvWT-treated maize B73 revealed upregulation of 12-OPDA biosynthesis and OPDA-responsive
69 clusters in the connected muscle, including upregulation of a cluster featuring Hsp90ab1 and Hsp70 a
70 e 2 (NOX2) generated oxidative injury causes upregulation of a constitutively active form of acetylch
71 ced expression of RAP2.6 and RAP2.6-mediated upregulation of ABA-responsive genes, indicating that CD
73 and loss-of-function analysis indicates that upregulation of Abi1 mediates PTEN loss-induced EMT and
74 ther research is needed to elucidate whether upregulation of ACE2 expression in airways and lungs has
75 hagocytosed by monocyte-derived DCs, causing upregulation of activation markers and production of pro
77 h muscle actin (alpha-SMA), and differential upregulation of aforementioned ECM genes/proteins with n
78 ependent kinase inhibitor 1B (p27(Kip1)) via upregulation of Akt1/PKB phosphorylation at serine 473,
83 acts in the nucleus, and contributes to the upregulation of antiviral effectors in response to type
85 addition, there was consistent and sustained upregulation of apoptosis-associated proteins CASP8, TNF
87 against TNF-alpha suppressed TLR2/4-mediated upregulation of astrocyte proliferation, supporting an a
90 ith macrophages resulted in significant mRNA upregulation of both C-type lectin receptors (CLR) Mincl
92 Accessory resistance mechanisms including upregulation of C. albicans drug-efflux, regulation of o
93 ell as MiR-155 oncogene, concomitant with an upregulation of caspase 3 and tumor suppressors i.e., p5
94 osome-mediated programmed cell death through upregulation of cathepsin B, Tnf and Bid in a neutrophil
95 entiation of primary CD34(+) cells revealing upregulation of CCAAT/enhancer-binding protein homologou
96 Evolving cells to larger sizes led to an upregulation of CCMs that improved the DIC uptake of thi
97 ng of HVEM to gD may contribute to efficient upregulation of CD8alpha but not PD1, TIM-3, CTLA4, or i
98 ignaling facilitates this by transcriptional upregulation of Chk1 expression in cells that have ATR k
100 We demonstrate that FPR activation leads to upregulation of complement receptors 1 and 3 as well as
101 reated with Ag(+) demonstrated a significant upregulation of components of the peroxiredoxin/thioredo
103 inly through the endogenous pathway) and the upregulation of costimulatory ligands CD70 and OX40L, th
104 ether the courtship execution capability and upregulation of courtship toward females are specified t
105 from negative feedback mechanisms, including upregulation of Csk homologous kinase (Chk) expression.
106 g characterized by loss of surface CD62L and upregulation of Cxcr4, heart infiltrating neutrophils ac
108 active oxygen species and p38 MAPK-dependent upregulation of cyclin-dependent kinase inhibitor 1A (Cd
109 tion of auxin and brassinosteroid genes, and upregulation of cytokinin transport/signaling genes, fro
110 t consequence of this metabolic shift is the upregulation of cytoprotective (CyTP) genes categorized
112 CIM6P/IGF2R controls the training-induced upregulation of de novo protein synthesis, including inc
114 aled downregulation of TGFbeta signaling and upregulation of differentiation pathways such as PDGFR s
116 a coronavirus (CoV), and contributes to the upregulation of downstream effector TCDD-inducible poly(
121 bited downregulation of Star and Cyp11b1 and upregulation of Ezh2, similar to ACC patients with a poo
122 cologically administered FAHFAs on extent of upregulation of FAHFA levels, glucose tolerance, or insu
123 y also had sufficient sensitivity to monitor upregulation of FAO in response to environmental glucose
124 ive receptor tyrosine kinases either through upregulation of FGF3 or HBEGF or increased MAPK signalin
125 ated with the downregulation of Th1/Th17 and upregulation of Foxp3(+)Treg.The study showed that a sub
129 genes associated with matrix degradation and upregulation of genes associated with cell proliferation
130 cited an increase in singing behavior and an upregulation of genes associated with metabolic processe
131 total retinal cells mainly brought to light upregulation of genes involved in antigen presentation a
135 ten mediated by inflammation, can lead to an upregulation of glutamine as an energy source for cancer
136 ocytes by stimulation is characterized by an upregulation of glycolysis, leading to an augmentation i
137 clinical outcomes with PAR4 inhibitors, and upregulation of GRK5 activity or signaling in platelets
141 esponsiveness with decreased mitogen-induced upregulation of IFN-gamma, TNF, IL-6, CXCL9, CXCL10, and
142 te fibrosis; however, myofibroblast specific upregulation of IGF-1 in the initiation and progression
148 the degradative pathway of macrophages with upregulation of immunity relevant cytokine and co-stimul
150 d by the receptor tyrosine kinase AXL, while upregulation of interleukin (IL)-12 depends strictly on
151 1 mutants exhibit a neurosecretion-dependent upregulation of intestinal ins-7 transcription, and dimi
153 inhibition of miR-16 maturation, leading to upregulation of JNK2 expression, c-Jun phosphorylation,
155 ulnerability to depressive behavior, whereas upregulation of Kv3.1 in dentate gyrus PV cells or acute
158 of ZNF529 in human hepatoma cells results in upregulation of LDL receptor and increased LDL uptake in
160 rs with proinflammatory stimuli and that the upregulation of lipogenesis may contribute to the resolu
162 MDA5-dependent, and quantitatively dramatic upregulation of many ISGs, which confers broad viral inf
164 gene expression induced by irisin including upregulation of markers for osteoclast differentiation a
167 PK3 was instead required for transcriptional upregulation of Mefv through negative control of the mec
169 n studies revealed changes to metabolism and upregulation of mitochondrial activity in mouse adipocyt
170 phosphorylation and prevented the prepartum upregulation of mitochondrial density and ETS proteins i
171 ty between prepartum maturation and neonatal upregulation of mitochondrial oxidative capacity may pro
172 essive mitochondrial fission and significant upregulation of mitochondrial superoxide, increasing int
174 ors such as MRTFA and SRF contribute to both upregulation of morphological genes as well as suppressi
178 r that are required for post-transcriptional upregulation of MYC and subsequent proliferation and dif
180 ellular signal-regulated kinase 5 (ERK5) via upregulation of myocyte enhancer factor 2 (MEF2) induces
181 HPV integration events were correlated with upregulation of nearby genes and endogenous retroviruses
182 ne acetylation, increased c-Jun binding, and upregulation of nearby genes implicated in progeria path
184 ysis of gene expression revealed significant upregulation of nitric oxide synthetase (NOS1 and NOS3)
187 WT and DUBmut viruses more broadly stimulate upregulation of over 2,800 genes, including networks ass
188 e and exacerbates tubular injury through the upregulation of p53-dependent pro-apoptotic signaling.
191 ownregulated miR-124 levels concomitant with upregulation of PARP-1 protein in dopaminergic-like neur
195 on of the cAMP signaling cascade, leading to upregulation of phosphodiesterase type 4 (PDE4), which c
196 with changes in Src signaling, including the upregulation of phosphorylated Lyn (pTyr507) and Fyn (pT
197 erm in vivo chemotherapy, display consistent upregulation of PIM1 as compared with bulk nontreated tu
200 ymphangiogenesis associated with significant upregulation of pro(lymph)angiogenic VEGF-A, VEGF-C, VEG
201 iltration of macrophages and neutrophils and upregulation of pro-inflammatory genes (TNF-alpha, IL-1b
203 downregulation of rapid conduction genes and upregulation of profibrotic gene programming, whereas an
205 after exposure to this vaccine revealed the upregulation of proinflammatory cytokines (TNF-alpha, IL
206 to chronic cortisol exposure, mediating the upregulation of proinflammatory genes that we reported p
207 which contributes to the observed down- and upregulation of proliferative and migratory genes, respe
209 ganisms respond to tissue damage through the upregulation of protective responses which restore tissu
210 eogenesis and amino acid metabolism, and the upregulation of protein degradation and endocytosis.
211 k in maturation of B cells in the spleen and upregulation of proteins associated with messenger RNA s
212 d content of xanthophylls esters, showed the upregulation of PYP1,2 and 6 genes during ripening only
214 esistance was partly mediated by paradoxical upregulation of RNA polymerase in response to rifampicin
215 after 6 hours of reperfusion, accompanied by upregulation of Rubicon, attenuation of autophagic flux,
217 vo by lipidome-wide remodeling, most notably upregulation of saturated lipids and cholesterol, result
218 within 12-15 days, a rapid, mostly transient upregulation of selective inflammatory markers including
219 mmunohistochemistry verified the significant upregulation of SERPINB1 and IL33 in healing gingiva.
220 py-mediated metastasis by which drug-induced upregulation of sEV secretion and PTX3 protein cargo pri
221 function (PAX5, CD79A, CD22, and FCRL1) and upregulation of several genes associated with senescence
222 egulation of Sr60 was associated with stable upregulation of several pathogenesis-related genes.
224 Here, we show that nerve injury-induced upregulation of sialyltransferase St3gal2 in sensory neu
226 cic aortic banding, we found that functional upregulation of SK2 channels in hypertrophic rat ventric
227 ls of ceramide, paralleled by a nonredundant upregulation of Smpd3, which encodes for the ceramide-ge
229 ctivation of macrophages, efferocytosis, and upregulation of specialized proresolving lipid mediators
231 xpress a unique cell surface glycocalyx with upregulation of sulfated glycosaminoglycans and charged
232 miR-24-3p and miR-145-5p caused significant upregulation of superoxide dismutase 2 and heme oxygenas
233 T cells and of antigen presenting cells via upregulation of suppressive factors such as checkpoint m
234 in EBV-positive Raji B cells resulted in an upregulation of surface HLA-DR and CD74 (invariant chain
236 and also enhances synaptic function through upregulation of synaptophysin and postsynaptic density p
237 Interestingly, GCM1 mediated NPFF-induced upregulation of syncytin 1 and syncytin 2, but not hCG b
238 PD exhibit an epigenetic and transcriptional upregulation of TET2, a master-regulator of cytosine mod
239 on occurs in response to glucagon-stimulated upregulation of TET3, not previously shown to be involve
240 more, in the shaking groups, CI-iPSCs showed upregulation of TGF-beta and Wnt signaling-related genes
241 sed on the anti-inflammatory benefits of the upregulation of the ACE2/Ang1-7/Mas axis and previously
242 ring UV with white light, shows the expected upregulation of the characteristic MAA mys gene cluster.
244 the cold-induced [Ca(2+) ](cyt) increase and upregulation of the cold-responsive CBF and COR genes.
247 measured by ABTS, DPPH and FRAP assays, and upregulation of the genes coding for the antioxidant enz
249 en together, our results reveal that chronic upregulation of the HBP under hemodynamic stress induces
251 r transcriptional profiling uncovered unique upregulation of the inhibitors of differentiation family
253 son's disease, we discovered evidence for an upregulation of the oxygen homeostasis maintaining pathw
257 nohistochemical fluorescent images presented upregulation of the rate-limiting enzymes for the produc
260 the jazD mutant was tightly correlated with upregulation of the Trp biosynthetic pathway but not wit
261 signaling through TNFR1 p55 was required for upregulation of these CLR and for cytokine secretion in
263 and matrix metalloproteinase-9, and we found upregulation of these genes in the premetastatic lungs.
269 t correlated with cell cycle arrest at G2/M, upregulation of tumor suppressor p53 and p21 protein.
272 delayed negative feedback loop, mediated by upregulation of ubiquitin-specific peptidase 18 (USP18).
274 ncoded complex I variants and a compensatory upregulation of unaffected oxidative phosphorylation com
277 gulation of TRPV1, CGRP, and IB4 binding and upregulation of VIP in the corresponding dorsal root gan
282 [(18)F]RoSMA-18-d(6) was used to detect CB2 upregulation on postmortem human ALS spinal cord tissues
283 d to asthma progression), and a lack of CD64 upregulation on the surface of monocytes (which, in conj
285 In contrast, during NMP, there was marked upregulation OXPHOS genes, but also of a number of immun
287 er exploration is needed to determine if AMP upregulation provides protection against CS-associated d
288 axis upstream of PGC-1alpha transcriptional upregulation, recapitulating a genetic response implicat
289 d improved OLT survival by suppressing p-p38 upregulation, ROS induction, and HMGB1 translocation (CC
290 ritical window of plasticity during which PV upregulation supports the acquisition of mature GABAergi
291 red axons by virtue of a dramatic glycolytic upregulation that arises in SCs as an inherent adaptatio
292 re-allocate resources away from internal pH upregulation to sustain elevated tissue growth, resultin
293 ditional innovations include the significant upregulation under abiotic stress of several expanded IC
296 ell-type-specific interferon-stimulated gene upregulation, we describe temporally aligned gene expres
297 , both FBXW7-inactivating mutations and MDM2 upregulation were found in melanoma clinical samples.
298 tant eyes, suggesting a mechanism for foxc1a upregulation when its function is compromised; interesti