ライフサイエンスコーパス: upstream regulator

1 the expression of miRNA-485, as a PGC1alpha upstream regulator.

2 TGF-beta1 was identified as the primary upstream regulator.

3 le evidence on the potential relevance of an upstream regulator.

4 bout how expression of Eya1 is controlled by upstream regulators.

5 compared with curated data sets to identify upstream regulators.

6 et there is little information regarding its upstream regulators.

7 sponses at the level of genes, pathways, and upstream regulators.

8 and Rictor were identified as potential key upstream regulators.

9 epair pathways and altered activities of key upstream regulators.

10 n analysis of transcription factors to infer upstream regulators.

11 s a Bayesian approach to infer corresponding upstream regulators.

12 titumor activity but circumvented control by upstream regulators.

13 e ERK1/2 activation by BCAR1/BCAR3 and other upstream regulators.

14 volves loss of duplicate copies of genes and upstream regulators.

15 ps into account to arrive at the best set of upstream regulators.

16 Transcriptional networks and upstream regulator analyses showed FOXA3, HNF4alpha, NR1

17 proinflammatory functional gene sets, while upstream regulator analysis coupled with Western blottin

18 Upstream regulator analysis demonstrated that extinction

19 Upstream regulator analysis further identified Myc as th

20 Pathways, functional and upstream regulator analysis of the intersections between

21 Upstream regulator analysis predicted the TLR4 ligands,

22 Upstream regulator analysis showed both RV-A and, althou

23 Upstream regulator analysis suggests neurodegeneration-a

24 The causal analytics tools 'Upstream Regulator Analysis', 'Mechanistic Networks', 'C

25 The causal analytics tools 'Upstream Regulator Analysis', 'Mechanistic Networks', 'C

26 bination of differential expression testing, upstream regulator analysis, clustering techniques, and

27 By leveraging causal network and upstream regulator analysis, we identified several candi

28 In addition, in myeloid cell DM and DFU upstream regulator analysis, we observed inhibition of i

29 ng of group-level data used a combination of upstream regulator and coexpression network analysis, fo

30 RARbeta acts as both an upstream regulator and downstream effector of miR-22, wh

31 vivo and identify Reelin as an extracellular upstream regulator and Erk1/2 as downstream effectors of

32 r-associated protein with death domain as an upstream regulator and transforming growth factor beta-a

33 These data were analyzed to predict upstream regulators and affected signaling pathways foll

34 t significant numbers of canonical pathways, upstream regulators and cellular functions.

35 By including both upstream regulators and downstream effectors, we can sys

36 a melanogaster, we first screened for FoxO's upstream regulators and downstream effectors.

37 ttern to that of cocaine SA with overlapping upstream regulators and downstream pathways predicted.

38 MAPKs bind to many of their upstream regulators and downstream substrates via a shor

39 However, the identities of the upstream regulators and downstream targets that mediate

40 is predicted that LPS and MPLA share similar upstream regulators and have comparable effects on canon

41 d that PO differentially regulates predicted upstream regulators and pathways, including LPS, members

42 f differentially affected cellular pathways, upstream regulators and predicted miRNA-target interacti

43 biphasic regulation is due to repression of upstream regulators and promotion of AMS protein degrada

44 ebrates, we report deep conservation of both upstream regulators and segmental activity of enhancer e

45 However, the upstream regulators and signaling pathways that control

46 We report the predicted upstream regulators and signalling pathways characterizi

47 y, we used RT-qPCR, RNA sequencing, pathway, upstream regulator, and histological analyses to demonst

48 n the Hippo field has focused on identifying upstream regulators, and a complex Hippo interactome has

49 tical role in modulating levels of KLF2, its upstream regulators, and its downstream target molecules

50 nally co-regulated mRNA subsets share common upstream regulators, and sequence elements generated by

51 entification of mRNA targets of FMRP and its upstream regulators, and the use of small molecules to s

52 , this is true even when fluctuations in the upstream regulator are far below the dissociation consta

53 involved in myogenesis have been identified, upstream regulators are less well understood.

54 s several components of the network, but its upstream regulators are still poorly characterized.

55 Thyroid- and TH-associated upstream regulators as well as thyroid-related diseases

56 e also identified top canonical pathways and upstream regulators associated with CXCL13-CXCR5 express

57 d IFN-gamma and IL-1beta as the top enriched upstream regulators associated with higher grade of immu

58 d an evolutionary shift in many of the known upstream regulators at the base of the arthropod lineage

59 nin signalling pathway, targeting up to nine upstream regulators at the same time, thus modulating th

60 ew statistical method that will infer likely upstream regulators based on observed patterns of up- an

61 reciprocally controls the activation of its upstream regulator c-Abl.

62 Because shared upstream regulators can ensure correlated gene expressio

63 retaining the pattern of gene expression and upstream regulators characteristic of each species.

64 tors Egr1, Atf3, Jun, Fos, and Mafb, and the upstream regulators Csf1r, Tgfb1, and Tgfbr1, which are

65 s-related pathways with LPS and cytokines as upstream regulators directly associated with heat stress

66 epigenome map, and a knockout of a predicted upstream regulator disrupts normal regeneration, validat

67 Modules of miRegulome (upstream regulators, downstream targets, miRNA regulated

68 response gene PHOTOPERIOD1 (Ppd-H1) and its upstream regulator EARLY FLOWERING3 (HvELF3).

69 - and gain-of-function studies indicate that upstream regulators, Expanded, Merlin and Kibra, play a

70 d that they do this in parallel to the known upstream regulator Fat cadherin.

71 ive RNA-binding protein RCF3 is an important upstream regulator for heat stress-responsive gene expre

72 tool called 'TRES' that predicts the likely upstream regulators for a given gene list.

73 support for shared dysregulated pathways and upstream regulators for two brain regions in human ASD b

74 s significant under expression of atrogenes, upstream regulators (FOXO1, FOXO3, NFKB1A), key componen

75 CN5L1 liver specific knockout mice and their upstream regulator, FoxO1 protein levels are decreased v

76 Few such cancer-specific upstream regulators have been described.

77 involving the MYC locus or mutations of its upstream regulators, how c-MYC expression is induced and

78 Novel, potential upstream regulators identified offer potential therapeut

79 okine G-CSF (r(2)=0.0683, p < 0.05), and its upstream regulator IL-17 (r(2)=0.0891, p < 0.05) both co

80 of the top diseases, functions, pathways and upstream regulators implied that a common underlying mec

81 d that can efficiently estimate p-values for upstream regulators in current biological settings.

82 on, and demonstrate differential activity of upstream regulators in different subcellular domains.

83 different components have been identified as upstream regulators in Drosophila and vertebrates.

84 Upstream regulators including the bZIP transcription fac

85 les indicated that several anti-inflammatory upstream regulators, including transforming growth facto

86 , NF-kappaB, complement, IL-6 signaling) and upstream regulators (INFgamma, IL-1beta, NF-kappaB, MYD8

87 ulation of the Hippo pathway and discovering upstream regulators is thus a major quest.

88 responsive to nutrient stress, including the upstream regulator KLF15, aminoacid catabolizing enzymes

89 Inspection of the predicted upstream regulators led to previously unsuspected roles

90 RNA interference of MLC-4, as well as of its upstream regulators, LET-502 (Rho-associated coiled-coil

91 ng of a dicitrate transporter fecBCDE and an upstream regulator likely for iron uptake, whereas the o

92 he membrane lipid transporter ABCA1, and its upstream regulator Liver X receptor (LXR) in the macroph

93 hat location-specific activation by distinct upstream regulators may enable distinct functional outpu

94 ) was used to identify enriched pathways and upstream regulators.Measurements and Main Results: Respo

95 f ATC and suggest that ASH1L, along with its upstream regulator miR-200b-3p and its downstream mediat

96 ibit ABCB1 is to target its cancer-specific, upstream regulators, mitigating damage to normal tissue.

97 sion and recruitment of its newly identified upstream regulator MYC.

98 In bioinformatics analysis of upstream regulator networks, the Cxcl8 pathway exhibited

99 kines such as IL-1beta, IL-6, TNF-alpha; and upstream regulator, NF-kappaB.

100 wn of vacuolar H+-ATPase 12 (vha-12) and its upstream regulator, nuclear hormone receptor 31 (nhr-31)

101 Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway

102 cytosolic form of Gpx4 was identified as an upstream regulator of a novel form of non-apoptotic cell

103 Here we characterize ROR1 as an upstream regulator of ABCB1.

104 Our study indicates MIF is a central and upstream regulator of ADPKD pathogenesis and provides a

105 tion, we have identified a tension-sensitive upstream regulator of alpha-actinin-4 as synaptopodin.

106 ferase assays, we identified AtWRKY33 as the upstream regulator of AtCYP94B1 in Arabidopsis.

107 to inhibition of protein phosphatase 2A, an upstream regulator of ATM.

108 This study identifies PKCzeta as a novel key upstream regulator of BA-regulated SHP function, reveali

109 As an upstream regulator of BCAT1 expression, we identified Mu

110 results show that ROCK1 acts as a prominent upstream regulator of Beclin1-mediated autophagy and mai

111 sive cytoplasmic adapter molecule that is an upstream regulator of both IkappaB kinase (IKK) and c-Ju

112 o persistent pain in EAE and functions as an upstream regulator of CaMKIIalpha signaling.

113 by inhibiting mTOR, placing mTOR as a novel upstream regulator of caspase-2 and supporting the possi

114 Interleukin 2 (IL-2) was an important upstream regulator of CD4+ T cells from VL patients, and

115 tified cyclin-dependent kinase (CDK) 6 as an upstream regulator of CDK2 controlling SAMHD1 phosphoryl

116 ctor AP-2gamma (TFAP2C) functions as a novel upstream regulator of Cdx2 expression and position-depen

117 Oxygen (O2) acts as a potent upstream regulator of cell function.

118 ations demonstrate that GflB is an essential upstream regulator of chemoattractant-mediated cell pola

119 nscription factor E2F3 (E2F3) as a prominent upstream regulator of cocaine-induced changes in gene ex

120 In this study, we identify TIP60 as a novel upstream regulator of DeltaNp63alpha.

121 epressor histone deacetylase 4 (HDAC4) as an upstream regulator of disease progression.

122 molog of the mammalian MAGI scaffolds, is an upstream regulator of E-Cad-based AJs during cell rearra

123 , these findings define DEPTOR as a critical upstream regulator of EC activation responses and sugges

124 Zip 1 (SPZ1) acts as a proto-oncogene and an upstream regulator of EMT during tumorigenesis.

125 Thus, we identify Aurora-B as a key upstream regulator of end-on conversion in human cells a

126 d a novel regulatory mechanism of MSI2 as an upstream regulator of ESR1 and revealed the clinical rel

127 findings reveal mitochondrial dynamics as an upstream regulator of essential mechanisms governing ste

128 Scube3 may be a critical upstream regulator of fast fiber myogenesis by modulatin

129 threonine-specific kinase p38 as a druggable upstream regulator of FOXC2 stability and function that

130 synthase kinase-3 (GSK3) was found to be an upstream regulator of FoxM1 because GSK3 inhibition or r

131 Hence, Fra-2 is a key upstream regulator of Foxo1 and Irf4 expression and infl

132 protein kinase, is a previously unidentified upstream regulator of Foxo1.

133 1alpha induction, suggesting that KLF5 is an upstream regulator of HIF-1alpha.

134 Ajuba, an upstream regulator of Hippo signaling that functions as

135 Retinoic acid is a known upstream regulator of HOXA5 expression.

136 , we identify the ABL2 tyrosine kinase as an upstream regulator of HSF1 protein expression and show t

137 re, we identify HNF4alpha as a potential key upstream regulator of IBD candidate genes.

138 helix-loop-helix (bHLH) transcription factor Upstream Regulator of IRT1 (URI) acts as an essential pa

139 uman peripheral blood cells and to define an upstream regulator of its activation through the release

140 In the present study, we identified the upstream regulator of Jab1/Csn5 expression and demonstra

141 hese data demonstrate that DLK is a critical upstream regulator of JNK-mediated neurodegeneration dow

142 itor of DNA binding protein 2 (ID2) as a key upstream regulator of KDR activation during myeloid diff

143 A2 transcription factor was identified as an upstream regulator of miR-194, consistent with a strong

144 hioredoxin-interacting protein (TXNIP) as an upstream regulator of miR-204, we also assessed whether

145 These findings identify 5-HT as an upstream regulator of mitochondrial biogenesis and funct

146 0 (MAP4K) member, we tested whether it is an upstream regulator of MLK3.

147 The loss of RASSF1A (an upstream regulator of MOAP-1) is one of the earliest det

148 ough Raptor-associated mTORC1 is a known key upstream regulator of mRNA translation, initiation and e

149 s analysis has identified p120-catenin as an upstream regulator of neurogenesis and cell cycle pathwa

150 A critical upstream regulator of NF-kappaB activation is protein ki

151 Collectively, our results uncover MLK4 as an upstream regulator of NF-kappaB signaling and a potentia

152 ticular, c-MYC was identified as a candidate upstream regulator of OGT target genes and OGT inhibitio

153 ggesting a novel role for this protein as an upstream regulator of p100.

154 ough CDC42 has previously been considered an upstream regulator of Pak2, we found a paradoxical decre

155 cers, indicative of DNA methylation being an upstream regulator of phylotypic enhancer function.

156 vious findings that cell surface GRP78 is an upstream regulator of PI3K/AKT signaling, we show here t

157 kappaB pathway, implying that Fyn is a major upstream regulator of proinflammatory signaling.

158 Thus, Trex1 is an upstream regulator of radiation-driven anti-tumour immun

159 Targeting CDK9 or c-MYC, an upstream regulator of RBPJ, with small molecules also de

160 identifies CHD7 as a previously unrecognized upstream regulator of Reln, and provides direct in vivo

161 sphate tensin homolog on chromosome 10 is an upstream regulator of renal PPM1A deregulation.

162 F breakpoint cluster region (Bcr) as a major upstream regulator of RhoA activity, stress fibers, and

163 variants, we provide evidence that Nck is an upstream regulator of RhoA-dependent, MMP14-mediated bre

164 aliana activating factor1 (ATAF1) as a novel upstream regulator of senescence.

165 We present evidence that the upstream regulator of sigma(F), the phosphatase SpoIIE,

166 our data suggest that Mesp-b is an intrinsic upstream regulator of skeletal muscle progenitors and th

167 , our data indicate that OsMADS26 acts as an upstream regulator of stress-associated genes and thereb

168 e ubiquitin-modifying enzyme TNFAIP3/A20, an upstream regulator of T cell receptor (TCR) signaling in

169 TGFbeta is a key upstream regulator of T cell reprogramming and contribut

170 primary response (MyD)88 pathway was crucial upstream regulator of TAK-1 and NF-kappaB p50/p65 activa

171 Finally, we establish ZNF143 as an upstream regulator of TARBP2 expression.

172 We also identify Stat3 as an upstream regulator of Tcf3.

173 rved an attenuation of NF-kappaB pathway, an upstream regulator of the aforementioned genes, concomit

174 e recapitulated by mutations in Expanded, an upstream regulator of the conserved Hippo pathway, and m

175 led that Pals1 functions as a dose-dependent upstream regulator of the crosstalk between Hippo- and T

176 ed ataxia telangiectasia mutated protein, an upstream regulator of the DDR pathway, and we found a si

177 rferon gamma was identified as a significant upstream regulator of the expression changes for RR and

178 We further identify that Brd4 is an upstream regulator of the expression of c-Myc which has

179 rexpression increased expression of PAR1, an upstream regulator of the Hippo pathway; PAR1 promotes i

180 KIBRA (kidney brain protein), an upstream regulator of the Hippo signaling pathway encode

181 uction in neurofibromin 2/Merlin protein, an upstream regulator of the Hippo signaling pathway, at le

182 t the cytoskeleton-membrane interface, as an upstream regulator of the Hippo signaling pathway.

183 onclude that alpha6 integrin is an essential upstream regulator of the IGF-1R survival pathway that r

184 LEAFY-like genes in Welwitschia, could be an upstream regulator of the MADS-box genes APETALA3/PISTIL

185 testicular development, thereby acting as an upstream regulator of the male pathway in P. sinensis.

186 res a bidirectional promoter with MAP3K4, an upstream regulator of the MAPK signaling pathway, and re

187 rter of EMT, we discovered that S100A4 is an upstream regulator of the master EMT regulators SNAIL2 a

188 The CaMKK2/CaMKIV relay is an upstream regulator of the oncogenic mammalian target of

189 monstrates that alpha2M*/CS-GRP78 acts as an upstream regulator of the PDK1/PLK1 signaling axis to mo

190 Fam20C is potentially an upstream regulator of the phosphate-regulating hormone f

191 findings support the notion that BAG2 is an upstream regulator of the PINK1/PARKIN signaling pathway

192 studies have demonstrated that cyclin D1, an upstream regulator of the Rb/E2F pathway, is an essentia

193 SCL1 and RET implicated ASCL1 as a potential upstream regulator of the RET oncogene.

194 nflammatory cytokine that acts as a critical upstream regulator of the SA secretory phenotype (SASP).

195 NB1 is an integral component and not only an upstream regulator of the spindle checkpoint pathway.

196 Thus, Pitx2 has long been considered as an upstream regulator of the transcriptional hierarchy in e

197 Another recent study predicted E2F3 as an upstream regulator of the transcriptional response to co

198 and identifies Hedgehog signaling as a novel upstream regulator of their prosensory function in the m

199 The transcription factor CREB is a predicted upstream regulator of this network and binds to the Zfp1

200 imicrobial function, was identified as a key upstream regulator of this process.

201 ranscriptional repressor ZBTB1 is a critical upstream regulator of TLS.

202 These results identify PSR1 as an upstream regulator of TORC1 and demonstrate that TORC1 i

203 Our results define Rspo1 as a key upstream regulator of two crucial pathways necessary for

204 ation factor 6 (ARF6), a small G protein and upstream regulator of type I phosphatidylinositol phosph

205 Our study identifies PKA as an upstream regulator of UBE3A activity and shows that an a

206 initiated by lysophosphatidic acid (LPA), an upstream regulator of Yap that can cause fetal haemorrha

207 However, no upstream regulators of ankyrin-G at synapses are known.

208 orks (TO-GCNs), which can be used to predict upstream regulators of any genes in the GCNs.

209 effectors of ATR have been established, the upstream regulators of ATR and the effect of such regula

210 binding proteins cofilin and VASP, which are upstream regulators of conformational integrin changes.

211 A molecular screen to find upstream regulators of cVg1 in normal embryos and in emb

212 all regulatory RNAs (microRNAs) that control upstream regulators of cytoskeletal proteins are also in

213 ta signaling and a network of four miRNAs as upstream regulators of DeltaNp63, providing key informat

214 Nck-interacting kinase (TNIK or MAP4K7), as upstream regulators of DLK/JNK signaling in neurons.

215 However, upstream regulators of Etv2 in hemangiogenesis, generati

216 n factors NAC25 and NAC1L were identified as upstream regulators of EXPA2 expression, gibberellin-med

217 Here, we identified upstream regulators of GhCYC3, a gene that specifies ray

218 teins in different developmental contexts as upstream regulators of Hox genes-as factors that interac

219 Very little is known about the upstream regulators of HSFs.

220 IL-1beta and upstream regulators of IFN-gamma, IL-12, and IL-18 were

221 known, relatively little is known about the upstream regulators of insulin transcription.

222 ) dual-specificity phosphatases as potential upstream regulators of ischemic neuronal death and Cdk4

223 ing a bioinformatics approach, we identified upstream regulators of KIM-1 after AKI.

224 vations highlight Chk1 and STAT3 as critical upstream regulators of KIM-1 expression after AKI and ma

225 AM-1 expression, and decreased expression of upstream regulators of KLF2 (ERK5 and MEF2).

226 GTPases, RhoA, Rac1, and Cdc42, as potential upstream regulators of membrane fusion.

227 However, the upstream regulators of miRNA biogenesis machineries rema

228 describe upstream regulators of mTORC1 activity which promote pal

229 mponents of the gamma-secretase complex, are upstream regulators of multiple cellular pathways via re

230 diovascular side effects because they target upstream regulators of muscle contraction.

231 We discuss the upstream regulators of myogenesis that lead to the activ

232 l border specifiers Pax3 and Zic1 are direct upstream regulators of neural crest specifiers Snail1/2,

233 rial function directly by phosphorylation of upstream regulators of PGC-1alpha and subsequently decre

234 Frs2alpha and tyrosine phosphatase Shp2, two upstream regulators of Ras signaling.

235 ving regeneration gene expression as well as upstream regulators of regeneration are identified and v

236 Although multiple upstream regulators of RhoA have been identified, the te

237 H), pyroglutamylated RFamide, and luqin, all upstream regulators of sexual reproduction.

238 To identify upstream regulators of Shank3 abundance, we performed a

239 he storage product of excess cholesterol, as upstream regulators of Tau early during AD development.

240 use of integrative analyses for identifying upstream regulators of the affected downstream molecular

241 We identified potential upstream regulators of the core network, including inter

242 Other upstream regulators of the Hippo pathway mediate this ef

243 lated or its relationship to the other known upstream regulators of the Hippo pathway remains poorly

244 High-confidence ASD risk genes emerge as upstream regulators of the network, and many risk genes

245 Prediction of upstream regulators of the OPC stroke transcriptome iden

246 Recently, oncogenic mutations in NRAS/KRAS, upstream regulators of the RAF/MEK/ERK pathway, have bee

247 eleasing Factor 1 (RasGRF1) and 2 (RasGRF2), upstream regulators of the Ras-ERK signaling cascade, on

248 g growth factor-beta, and IL-13 as potential upstream regulators of the serum protein patterns in the

249 y, to create membrane domains that partition upstream regulators of the TORC1 and TORC2 signaling pat

250 Although many mysteries remain about the upstream regulators of these changes, we review the core

251 A TGFbeta-regulated miRNA network acted as upstream regulators of this oscillatory expression of De

252 nuity Pathway Analysis demonstrated that the upstream regulators of type I and type III interferons,

253 n factor that modulates the transcription of upstream regulators of WNT and MAPK-ERK signaling to saf

254 ockout of Lats1 and Lats2 kinase, the direct upstream regulators of YAP and TAZ.

255 hat this approach can correctly identify the upstream regulator on expression data sets for which the

256 thout further significant changes to pathway/upstream regulator or network profiles.

257 oma, only a handful of lincRNAs are known as upstream regulators or downstream effectors of oncogenes

258 t this regulation occurs not at the level of upstream regulators or primary cilia, but rather at the

259 Suppression of phc1 or its upstream regulator, p53, rescues the loss of both Notch

260 encing miR-34a expression independent of its upstream regulator, p53.

261 etal muscle, and with the suppression of the upstream regulators PGC1alpha and AMPKalpha2.

262 updosing detected minimal changes to pathway/upstream regulator profiles despite 32.5% symptom reduct

263 We compared several upstream regulator profiles, including constant expressi

264 overed cell-type heterogeneity and predicted upstream regulator proteins that mediate cell survival,

265 ences in the expression or function of their upstream regulators, providing insights into the genetic

266 sub-networks and the connections with their upstream regulator receptors to obtain a systems view of

267 nd microtubule-associated proteins; however, upstream regulators remain controversial due to the conf

268 viously unrecognized roles for GPR10 and its upstream regulator REST in the pathogenesis of uterine f

269 abling convergent advection of MyoII and its upstream regulators Rho1 GTP, Rok and MyoII phosphatase.

270 Phosphorylation by its upstream regulator, RIPK3, triggers MLKL's conversion fr

271 (DNMT3a) in human cancer, the nature of its upstream regulator(s) and relationship with the master c

272 However, the upstream regulator(s) of 53BP1 function in DNA repair re

273 f yes-associated protein 1 (YAP1) and of its upstream regulator SRC.

274 We show that, in contrast to canonical upstream regulators such as Crumbs, Kibra, Expanded, and

275 This is all the more important since it is upstream regulators such as this that need to be directl

276 s was undisturbed, depletion of G3BP1 or its upstream regulator TDP-43 disturbed normal interactions

277 ne-triggered activation of NF-kappaB and its upstream regulator TGF-beta-activated kinase-1 in murine

278 s response networks frequently have a single upstream regulator that controls many downstream genes.

279 e Bayesian network can be queried to suggest upstream regulators that can be causally linked to the a

280 genes (DEGs), over-represented pathways, and upstream regulators that contribute to kidney disease pr

281 complex with transcription factors and their upstream regulators that control Ccl5 expression.

282 n VSMCs and connects these roles to specific upstream regulators that control their expression.

283 identification of a repertoire of intrinsic upstream regulators that drive the dopaminergic stress r

284 Upstream regulators that orchestrate this remarkable cha

285 geting endothelin and angiotensin, which are upstream regulators that promote VSM contraction, was no

286 in the core autophagy machinery and describe upstream regulators that respond to extracellular and in

287 Early transcriptomic changes and predicted upstream regulators that were found in all three procedu

288 icrodeletions encompassing p190RhoGAP or its upstream regulator, the Abl2/Arg tyrosine kinase, have b

289 Loss of Abl or its upstream regulator, the adaptor protein Disabled, lead t

290 ied, little is known about the role of their upstream regulators, the Rho guanine nucleotide exchange

291 ce of ANAC019, suggesting that ANAC019 is an upstream regulator these genes for drought response and

292 rrelations associated with expression of the upstream regulators TSC1, TSC2, AKT, p-AKT, PDPK1, PTEN,

293 Then, we identified its upstream regulator UBE2T which promotes GC progression v

294 WNK1 increases the expression of the PI3KC3 upstream regulator unc-51-like kinase 1 (ULK1), its phos

295 While Notch signaling, including its upstream regulator Vegf, is known to regulate this proce

296 Our results suggest that Arp2/3 and the upstream regulator, WAVE2, are essential co-factors hija

297 In the screen for upstream regulators we identified a LONG PALE HYPOCOTYL

298 In addition, key upstream regulators were predicted to be commonly regula

299 dentified transcription factor USF2 as their upstream regulator, which was also increased in nonrespo

300 triiodothyronine (reverse) were inferred as upstream regulators with differences in incidence and st