ライフサイエンスコーパス: ureter

1 other tonic SMCs (gastrointestinal, urethra, ureter).

2 t with IVU in one of 12 segments (lower left ureter).

3 lable in 18 of 22 patients (30 of 38 treated ureters).

4 able for 25 of 32 patients (45 of 56 treated ureters).

5 multiple tubular stenoses (e.g., bile ducts, ureters).

6 ective measure against thermal injury to the ureter.

7 and instilment of diluted contrast into the ureter.

8 plex in cultured cells and in the developing ureter.

9 through the artery or retrograde through the ureter.

10 that form the wall of the forming mammalian ureter.

11 ntiating into the collecting duct system and ureter.

12 omain of the UB that differentiates into the ureter.

13 ) is not dependent on fluid flow through the ureter.

14 ell types in the developing and mature mouse ureter.

15 he intrarenal collecting system and proximal ureter.

16 in visualization of the lower segment of the ureter.

17 ss of five different approaches to the lower ureter.

18 ureterectomy is the management of the distal ureter.

19 ysiologically relevant conditions, in intact ureter.

20 re needed to solve the dilemma of the distal ureter.

21 nt atrophy in the kidneys with an obstructed ureter.

22 artially rescue growth and elongation of the ureter.

23 ed regions of transitional epithelium of the ureter.

24 als emanating from the tips of the branching ureter.

25 ng to the expansive growth of the kidney and ureter.

26 y play in initiating force in the guinea-pig ureter.

27 intravesical implantation of the transplant ureter.

28 t dysplastic kidney with a dilated, tortuous ureter.

29 strating both patency and obstruction of the ureter.

30 symmetrical collecting duct tree that has no ureter.

31 erentiation in the tissues of the developing ureter.

32 d urine was collected directly from the left ureter.

33 n in the ureteropelvic junction and proximal ureter.

34 g the renal excretion pathway from cortex to ureter.

35 ll cancer and cancers of the renal pelvis or ureter.

36 assessment of the kidney parenchyma and the ureter.

37 is transport urine from the kidneys into the ureter.

38 and it can be confused with leakage from the ureter.

39 present in the pelvicalyceal system and the ureter.

40 teric buds along the Wolffian duct or duplex ureters.

41 t Six1-deficient mice lack kidneys, but form ureters.

42 MC differentiation was observed in Six1(-/-) ureters.

43 success for strictures of transplant kidney ureters.

44 Reflux occurred in 16 of 45 ureters.

45 Reflux occurred in seven of 30 ureters.

46 of the kidneys, but severe rejection of the ureters.

47 tion of CD14 mRNA in kidneys with obstructed ureters.

48 l epithelium lining the bladder, kidneys and ureters.

49 ullary architecture, a collecting system and ureters.

50 ximal ureter, seven; midureter, four; distal ureter, 15; bladder, one) and not found in 752 locations

51 i were found in 113 locations (pyelocalyceal ureter, 86; proximal ureter, seven; midureter, four; dis

52 Ureter abnormalities occur in 1-2% of the human populati

53 e of the Wolffian ducts, and that the distal ureter abnormalities seen in Rara(-/-) Rarb2(-/-) and Re

54 ng renal hypoplasia, hydronephrosis and mega-ureter, abnormalities also seen in mice with mutations i

55 The ureter actively propels tubular fluid from the renal pel

56 ndicated and a stent cannot be placed in the ureter, an extra-anatomic stent (EAS) could be used to b

57 ssical open technique of securing the distal ureter and bladder cuff achieves this principle and has

58 f the various methods of managing the distal ureter and bladder cuff currently employed.

59 chnique, laparoscopic stapling of the distal ureter and bladder cuff, the "pluck" technique, and uret

60 While ureter and bladder histology appeared normal, postnatal

61 hese results suggest that Dlg1 expression in ureter and CND-associated mesenchymal cells is essential

62 rade flow of urine from the bladder into the ureter and is associated with reflux nephropathy, the ca

63 GDNF/RET signaling is required for ureter and kidney development, and cells lacking Ret are

64 tor (Th1 and Th17) and regulatory T cells in ureter and kidney tissues, and they induced T cell-media

65 hat Drosophilarenal stem cells (RSCs) in the ureter and lower tubules comprise a unique, unipotent re

66 roscopy for reconstructive procedures of the ureter and may represent a potential solution to some of

67 increased most of all cancers after kidney, ureter and mixed stones while bladder cancer was increas

68 strointestinal anastomosis instrument on the ureter and peri-ureteral tissue.

69 r Six1 in establishing a functionally normal ureter and provide new insights into the molecular basis

70 cyst complex, in the epithelial cells of the ureter and renal collecting system resulted in late gest

71 UPIIIa was expressed in nascent urothelia in ureter and renal pelvis of human embryos, and it is sugg

72 important for the normal peristalsis of the ureter and report an association between the expression

73 at is required for proper positioning of the ureter and that depends on Ret signaling.

74 The average distance between the ureter and the tumour in axial CT view was 20.8 (+/- 2.9

75 up CT urography in the same one-third of the ureter and there were no secondary signs of a mass with

76 functional muscularization in the top of the ureter and this is followed by congenital hydronephrosis

77 clitoris, corpus cavermosum, kidney, testis, ureter and urethra have been created in the laboratory,

78 of contraction in precapillary arterioles in ureter and vas deferens.

79 dney to the bladder, causing dilation of the ureter and/or renal pelvis.

80 ds on patent connections between the kidney, ureters and bladder that are established when the ureter

81 r phenotype, is prevalent on bacteria in the ureters and bladder.

82 sion by UPEC coincides with ascension of the ureters and colonization of the kidney.

83 ephros/mesonephric duct gives rise to absent ureters and hence absent homolateral kidney; blind endin

84 turation process can result in malpositioned ureters and hydronephrosis, a common cause of renal dise

85 D patterning prompts the formation of duplex ureters and kidneys.

86 ds, resulting in the development of multiple ureters and multiplex kidneys.

87 e of urine from the bladder into one or both ureters and often up to the kidneys, and mainly affects

88 to irregular connections between the distal ureters and the bladder.

89 Precise connections between the ureters and the trigone are crucial for proper function

90 rs (AMPs) move posteriorly to form the adult ureters and, consecutively, the renal stem cells.

91 cell, 24 transitional cell renal pelvis and ureter, and 22 other kidney cancers.

92 l urothelial cancers combined (renal pelvis, ureter, and bladder cancers: adjusted IRR 2.2, 95% CI 0.

93 colorectum, kidney, liver, pancreas, bladder/ureter, and gastroesophagus, which collectively account

94 s of the urinary tract, such as the bladder, ureter, and renal pelvis.

95 the fate choice between collecting duct and ureter, and show that an environment rich in BMP4 promot

96 scle with a more minor contribution from the ureter, and that trigone formation depends at least in p

97 oprotein expressed in kidney, spleen, brain, ureter, and urinary bladder.

98 esonephric tubules, ureteric bud, developing ureter, and Wolffian duct.

99 -the kidneys, intrarenal collecting systems, ureters, and bladder--and thus allows patients with hema

100 mation; pitch of 1.5) and US of the kidneys, ureters, and bladder.

101 ium that lines the renal calyces and pelvis, ureters, and bladder.

102 at the conclusion of the study, the kidneys, ureters, and bladders were radiographed for the presence

103 ound that LCN2 was expressed in the bladder, ureters, and kidneys of mice subject to UTI.

104 rom physiologically relevant sites (bladder, ureters, and kidneys).

105 Of 5,087 bacteria measured in bladders, ureters, and kidneys, only 7 (0.14%) were identified as

106 results in the complete absence of kidneys, ureters, and sex specific epithelial structures derived

107 nd had undergone radiography of the kidneys, ureters, and urinary bladder (KUB) and diuretic Tc-MAG3

108 Thus, the developing distal ureter appears to be a unique anatomical structure which

109 akin expression) of the distal non-branching ureter are inherent properties of this portion of the UB

110 Ureters are fundamental for keeping kidneys free from ur

111 In support of this hypothesis, ureter arrest is rescued by lowering beta-catenin levels

112 The distance between the tumour and ureter as well as the tumour size were measured on axial

113 m), and stone location (upper, mid, or lower ureter) as minimisation covariates.

114 hree patients; none occurred in the unfilled ureter at index CT urography.

115 rial in the kidney and its appearance in the ureter at or below the level of the lower pole of the ki

116 uent bending and luminal constriction of the ureter at the UPJ marks the transition from a functional

117 ansplantation SSIs were deceased donor, thin ureters at kidney transplantation, antithymocyte globuli

118 ta, this indicates that, although the distal ureter (at least early in its development) retains some

119 f the stomach, small intestine, bladder, and ureters attributable to the loss of visceral SMCs disrup

120 extracellular matrix-related genes in mutant ureters before the onset of hydronephrosis.

121 met the following inclusion criteria: kidney ureter bladder (KUB) and decubitus views obtained, with

122 affecting the renal parechyma, renal pelvis, ureter, bladder and urethra; they show evidence of share

123 th urothelial carcinoma of the renal pelvis, ureter, bladder, or urethra at 16 sites in Finland, Germ

124 ncer, including cancers of the renal pelvis, ureter, bladder, or urethra, from eight hospitals in the

125 Importantly, the ureter-bladder junction is normally formed.

126 nthesis is not inhibited, BMP4 beads inhibit ureter branching and expression of Wnt 11, a target of g

127 upregulated canonical Wnt signaling disrupts ureter branching in this mutant.

128 mbryos, GDNF is sufficient to induce ectopic ureter buds in the posterior nephric duct, a process inh

129 just blocked the NP elimination through the ureter but also slowed down their transport from the med

130 tion-contraction (EC) coupling in guinea-pig ureter, by measuring membrane currents, action potential

131 -renal collecting system and the extra-renal ureter, by responding to signals in its surrounding mese

132 ex vivo organ culture suggested that ectopic ureters can regress over time, leaving behind a dysplast

133 inking-water arsenic causes renal pelvis and ureter cancer.

134 , 1.6; 95% CI, 0.8-3.0) and for renal pelvis/ureter cancers (OR, 1.7; 95% CI, 0.5-5.4).

135 For renal pelvis and ureter cancers, the adjusted odds ratios by average arse

136 In 16 ureters, chondrocyte mounds were absent in six, unilobed

137 By decreasing contractions in the ureter, clinically prescribed oral vasodilators may impr

138 including ureteric bud (UB) ectopia, double ureters/collecting systems, delayed primary branching of

139 the kidneys of C57BL/6 mice with obstructed ureters, compared with the contralateral kidneys, at 7 a

140 der mucosal regeneration and growth over the ureter, confirming the spontaneous development of a good

141 The mammalian ureter consists of a mesenchymal wall composed of smooth

142 The mammalian ureter contains two main cell types: a multilayered wate

143 The number of ureter contractions was significantly higher in miR-143/

144 ance on the renal system, where it regulates ureter contractions.

145 In keeping with this, isolated ureters cultured in the absence of surrounding tissues e

146 These studies provide an explanation for ureter defects underlying some forms of obstruction in h

147 Similar kidney and ureter defects were observed in RET9(Y1015F) mice that c

148 nd control cultures from finite bladder- and ureter-derived NHU cell lines at different time points u

149 etic regulator Brg1, but the role of Brg1 in ureter development is not well understood.

150 BMP4 is a mesenchymal regulator promoting ureter development, while GREM1 is necessary to negative

151 muscle progenitor cells during murine kidney-ureter development.

152 hat Brg1 expression unifies three aspects of ureter development: maintenance of the basal cell popula

153 hain (MLC) phosphorylation in the guinea-pig ureter, did not affect electrical activity or Ca2+ but s

154 Uncommitted epithelial progenitors of the ureter differentiated into intermediate cells at E14.5.

155 Transplant ureters displayed a significant decrease of NIR perfusio

156 f adhesins bound to immortalized vaginal and ureter epithelial cells, further reinforcing specific as

157 ation activity in mice is found to result in ureter epithelial tumors.

158 uitously (Alk3) or exclusively in the WD and ureter epithelium (Alk6).

159 Ureter epithelium developed severe hyperplasia, leading

160 Developing and adult ureters express the epigenetic regulator Brg1, but the r

161 he urothelial progenitor cells that line the ureter fail to differentiate into superficial cells, whi

162 , Ca2+ and phasic force in intact guinea-pig ureter, following physiological activation.

163 oderm results in bilateral duplex kidney and ureter formation.

164 icate that the border between the kidney and ureter forms where mesenchymal tissues originating in tw

165 branching, and delayed disconnection of the ureter from the common nephric duct (CND).

166 synergistically regulate SMC development and ureter function and that their gene products form a comp

167 he developmental expression of alphaSMA from ureter growth and elongation.

168 n initiate visceral pain in urinary bladder, ureter, gut and uterus.

169 cell carcinoma of the renal pelvis or distal ureter has been extirpated with successful oncologic out

170 supporting specific approaches to the distal ureter have been published, including implementing robot

171 eteral strictures and symptomatic retrocaval ureters have been repaired with long-term follow-up demo

172 compared to nonmalignant cell cancer of the ureter (HCV29 cells).

173 with the proximal and distal segments of the ureter in directing differentiation, the role of bone mo

174 Moreover, the peristalsis of the ureter in the absence of the kidney in the Six1-/- mouse

175 population is maintained at the tips of the ureter in the presence of signals promoting tubulogenesi

176 enally and extended caudally surrounding the ureter in the retroperitoneum.

177 rs were present in 41 partially nonopacified ureters in 20 patients.

178 Reimplantation of refluxing ureters in children has been demonstrated to provide sim

179 /- mice were found to have apparently normal ureters in the absence of a kidney, suggesting that the

180 mg) is reported to improve the depiction of ureters in the excretory phase of the examination.

181 DLGH1 is expressed in the developing ureter; in its absence, the stromal cells that normally

182 tion of UUO in rats by ligation of the right ureter, increased expression of the alpha8 integrin chai

183 s the concept of origin of the ureters (with ureters inducing renal development) by the former and th

184 chnique involved placement of the transplant ureter into a shallow, mucosa-denuded, rectangular troug

185 ssential for correct insertion of the distal ureters into the bladder, and that these events are medi

186 Stricture formation in the distal ureter is a common consequence of treatment for patients

187 Ureter maturation, the process by which the ureter is displaced to the bladder wall, represents an e

188 After the basic shape of the mammalian ureter is established, its epithelia mature and a coat o

189 the growth and development of the unbranched ureter is largely independent of the more proximal porti

190 -) mice exhibit renal agenesis, although the ureter is present.

191 rs and bladder that are established when the ureter is transposed from its original insertion site in

192 Iatrogenic injury of the ureters is a feared complication of abdominal surgery.

193 n, where the renal pelvis transitions to the ureter, is the most commonly obstructed site in CON.

194 abnormal development of the renal pelvis and ureter, leading to defective pyeloureteral peristalsis,

195 A lack of Six1 in the ureter led to hydroureter and hydronephrosis without ana

196 These abnormalities in the ureter led to severely impaired ureteric peristalsis.

197 kidney, with subsequent periods of the left ureter ligation, causes irreversible right kidney failur

198 nto a uroplakin-positive, broad, unbranched, ureter-like 'trunk' from one end of which true collectin

199 h but instead differentiated into multilayer ureter-like epithelia displaying robust expression of th

200 g ducts into uroplakin-positive, unbranched, ureter-like epithelial tubules.

201 a4(-/-);Epha7(-/-) (DKO) mice display distal ureter malformations including ureterocele, blind and ec

202 for understanding the pathogenesis of human ureter malformations.

203 Such molecules could solve the ureter mapping problem by providing real-time anatomic a

204 reduced Ret expression and apoptosis during ureter maturation and evidence of reduced retinoic acid

205 panied by reduced branching, abnormal distal ureter maturation and insertion, and smooth muscle orien

206 hymal cells is essential for ensuring distal ureter maturation by facilitating retinoic acid signalin

207 Here we show that ureter maturation depends on formation of the 'trigonal

208 t birth reveals hydronephrosis and defective ureter maturation, abnormalities that our results sugges

209 ities in ureteric bud branching or in distal ureter maturation, and no hydronephrosis.

210 Ureter maturation, the process by which the ureter is di

211 in humans and redefine the current model of ureter maturation.

212 ase of the bladder in a process that we call ureter maturation.

213 n 1 (cIAP1) to modulate caspase 3,7-mediated ureter maturation.

214 During development, ureters migrate by an unknown mechanism from their initi

215 topic BMP4 signaling is sufficient to induce ureter morphogenesis in domains of the UB normally fated

216 lear whether Six1 plays a role in regulating ureter morphogenesis.

217 that Six1 is differentially expressed during ureter morphogenesis.

218 tailbud-derived mesenchyme, is required for ureter morphogenesis.

219 In seven ureters, mounds were unilobed in five and multilobed in

220 dently, connecting at mid-gestation when the ureters move from their primary insertion site in the Wo

221 s on a complex series of events in which the ureter moves from its initial branch point on the nephri

222 In unilateral ureter obstructed mouse kidney, which is a renal fibrosi

223 es fibrosis and inflammation in a unilateral ureter obstruction (UUO) model of CKD in mice.

224 ily expression is decreased after unilateral ureter obstruction and this significant decrease in miR-

225 aluated renal inflammation during unilateral ureter obstruction in CSF-1-deficient (Csf1(op)/Csf1(op)

226 imilar results were obtained in a unilateral ureter obstruction model and in human diseased kidney bi

227 tion of type I collagen following unilateral ureter obstruction of the kidney, and quantitative prote

228 efects observed in the mutant were caused by ureter obstruction.

229 Reflux into the transplant ureter occurred in 19/27 (70%) of children tested (by ra

230 ined as the intrarenal collecting system and ureter of one kidney) basis.

231 Cultured ureters of both the wild-type and Six1 mutant become con

232 showed 108 differentially expressed genes in ureters of miR-143/145-deficient mice.

233 In addition, ureters of Six1-/- urinary tracts (i.e., lacking a kidne

234 Dysfunction of the ureter often leads to urine flow impairment from the kid

235 kidney, including duplex kidneys and double ureters, one of which is a hydroureter.

236 e been modified to accommodate the pediatric ureter, optics advanced, and access sheaths are used to

237 ffecting either the upper tract (kidneys and ureters) or lower tract (reproductive organs) of the gen

238 astatic urothelial carcinoma of the bladder, ureter, or urethra not amenable to curative surgery and

239 us in urine can be derived from the kidneys, ureter, or urinary bladder, we evaluated whether measure

240 This confirmed the ability of GDNF to induce ureter outgrowth and epithelial branching in vivo.

241 he intrarenal collecting system and proximal ureter (P < .001).

242 r role in modulating the excitability of the ureter, particularly via curtailing the action potential

243 r salts, the upper urinary tract, namely the ureter, pelvis, and calyces, could be depicted with radi

244 ent of this clinically important function of ureter (peristaltic movement of urine) is not dependent

245 red ureteral relaxants therefore may improve ureter-related conditions.

246 In severe cases dilatation of the ureter, renal pelvis, and calyces might be seen.

247 m the WD and accessory budding from the main ureter, respectively.

248 ariant anatomy of renal arteries, veins, and ureters, respectively.

249 Examination of the ureters revealed the presence of a multi-cell layered tu

250 oved mean opacification scores in the distal ureters (right, P =.004; left, P =.006).

251 We also show, by using ex vivo porcine ureter segments and sedated pigs that, with respect to t

252 ocations (pyelocalyceal ureter, 86; proximal ureter, seven; midureter, four; distal ureter, 15; bladd

253 collecting system and that which becomes the ureter should facilitate distinguishing the developmenta

254 ed cell proliferation, and dilatation of the ureter similar to mice with kidney-specific inactivation

255 transcriptional repression, thus implicating ureter smooth muscle cell development in the pathogenesi

256 o inhibit ectopic budding from the WD or the ureter stalk by antagonizing inductive signals from the

257 cells surrounding the Wolffian duct (WD) and ureter stalk, whereas bone morphogenetic protein (BMP) t

258 sualization of structure and function of the ureters starts within minutes after ZW800-1 injection an

259 othelial differentiation at the level of the ureter, suggesting that Tbx18 acts via mesenchyme as an

260 rounding the distal collecting ducts and the ureter suggests that sonic hedgehog acts as a paracrine

261 ransitional cell carcinoma of the transplant ureter (TCCtu).

262 Amyloid fibrils were isolated from a ureter that was obstructed by extensive infiltration of

263 rine from the kidneys to the bladder via the ureters that propel urine to the bladder via peristalsis

264 cts and continues into the epithelium of the ureter -- the urinary outflow tract that connects the ki

265 al and bifid branching occurs (including the ureter), the mesenchyme probably restricts lateral branc

266 uch as ectodermal placodes, the trachea, the ureter, the gut and the neuroepithelium.

267 In rat, but not guinea-pig ureter, three Rho-kinase inhibitors, Y-27632, HA-1077 an

268 However, no leakage from the ureter to the retroperitoneum was observed, proving that

269 ysplasia, vesicoureteral reflux, and ectopic ureters to name a few, the genetic and biochemical modul

270 vesicoureteral reflux, caused by failure of ureters to separate from Wolffian ducts and migrate to t

271 g pattern of light-emitting bacteria through ureters to the kidneys.

272 ction, colonizes the bladder and ascends the ureters to the proximal tubules of the kidneys, leading

273 tead undergoes apoptosis, a crucial step for ureter transposition controlled by vitamin A-induced sig

274 ) into the intra-renal collecting system and ureter, two tissues with unique structural and functiona

275 1 in the metanephric mesenchyme, but not the ureter, under control of the Eya1 promoter.

276 would grow over the anterior surface of the ureter until they met the advancing mucosal edges from t

277 d exhibits structural defects in kidneys and ureters upon homozygosity.

278 conditionally ablated Brg1 in the developing ureter using Hoxb7-Cre and found that Brg1 expression is

279 Each calcification along the ureter was classified as a phlebolith or a ureteral calc

280 Each collecting system and ureter was divided into six segments that were assigned

281 In 12 piglets, the distal ureter was obstructed for 60 minutes, followed by intrav

282 The ureter was the earliest structure of the KTx affected by

283 The contrast medium in the renal pelvis and ureters was virtually removed from excretory phase image

284 a, decreased branching and elongation of the ureter were also observed.

285 d by action potentials in guinea-pig and rat ureter were investigated.

286 t effects involving the lower segment of the ureter were seen with any technique; however, there were

287 ctility and calcium transients in intact rat ureters were compared between strains.

288 While ureters were histologically normal, E15.5 Fgfr2(ST-/-) m

289 components of kidney allografts (parenchyma, ureter) were acquired 15 and 45 minutes after reperfusio

290 plasia results from reduced branching of the ureter, whereas the ectopic UV junction and double colle

291 have not yet resulted in renal tissue with a ureter, which would be needed for engineered kidneys to

292 reteric pathology involving all parts of the ureter with varying cause has been reported.

293 ng ureterocele, blind and ectopically ending ureters with associated hydroureter, megaureter and hydr

294 Narrowed ureters with hydronephrosis were found only in the Tl1a

295 owever, retains the concept of origin of the ureters (with ureters inducing renal development) by the

296 e most common methods of managing the distal ureter, with emphasis on contemporary oncologic outcomes

297 s to promote the elongation of the branching ureter within the metanephros, thereby promoting kidney

298 In 23 treated ureters without reflux, mounds were unilobed in 21 and m

299 In 29 treated ureters without reflux, mounds were unilobed in 28 and m

300 elops independently of the bladder, from the ureters, Wolffian ducts or a combination of both; howeve