ライフサイエンスコーパス: ureteric

1 such as solitary kidneys, hypodysplasia, or ureteric abnormalities (in a total of 29 affected indivi

2 Capsular, ureteric and vascular injuries were all significantly mo

3 sis extends our current understanding of the ureteric branch tip niche.

4 ian kidney, an epithelial progenitor pool at ureteric branch tips (UBTs) creates the urine-transporti

5 we demonstrated a requirement for Ilk during ureteric branching and cell cycle regulation in collecti

6 cultured embryonic murine kidneys decreased ureteric branching and p38MAPK activation.

7 whereas Fgfr2(UB-/-) kidneys had more severe ureteric branching defects than Frs2alpha(UB-/-), Fgfr2(

8 Hoxb7cre line (Fgfr2(UB-/-)) develop severe ureteric branching defects; however, ureteric deletion o

9 racterize the processes of nephrogenesis and ureteric branching during kidney development have many l

10 opmental disorder characterized by defective ureteric branching morphogenesis and nephrogenesis, rank

11 gfr2(UB-/-) mice have more severe defects in ureteric branching morphogenesis than previously reporte

12 Furthermore, the loss of ureteric Brg1 resulted in failure of Shh expression, whi

13 Fgfr1/2(Mes-/-) mice develop a ureteric bud (and occasionally an ectopic bud) that does

14 g fibroblast growth factor receptor 2 in the ureteric bud (Fgfr2(UB-/-)) and in littermate controls.

15 Ectopic or supernumerary ureteric bud (UB) branches can result in urinary tract o

16 Ureteric bud (UB) branching during kidney development de

17 n of both the Hdac1 and Hdac2 genes from the ureteric bud (UB) cell lineage of mice causes bilateral

18 at isolated metanephric mesenchymal (MM) and ureteric bud (UB) cells grown in three-dimensional (3D)

19 nduction of metanephric mesenchymal (MM) and ureteric bud (UB) cells.

20 s study, we showed that Adam10 deficiency in ureteric bud (UB) derivatives leads to a decrease in uri

21 s of the kidney and urinary tract, including ureteric bud (UB) ectopia, double ureters/collecting sys

22 Ureteric bud (UB) emergence from the Wolffian duct (WD),

23 Mdm2 mRNA and protein are expressed in the ureteric bud (UB) epithelium and metanephric mesenchyme

24 d epithelial differentiation of the isolated ureteric bud (UB) independent of glial cell line-derived

25 in renal and urinary tract mesenchyme led to ureteric bud (UB) induction defects and vesicoureteral r

26 ct morphogenesis requires subdivision of the ureteric bud (UB) into the intra-renal collecting system

27 rphogenesis requires the sub-division of the ureteric bud (UB) into the intra-renal collecting system

28 Removal of Nf2 or Lats1/2 from the ureteric bud (UB) lineage causes loss of branching morph

29 of human pluripotent stem cells (hPSCs) into ureteric bud (UB) progenitor-like cells.

30 interactions that direct arborization of the ureteric bud (UB) remain incompletely understood.

31 ate that Fras1 is expressed in the branching ureteric bud (UB), and that renal agenesis occurs in hom

32 ed cap mesenchyme surrounding the tip of the ureteric bud (UB), is downregulated after differentiatio

33 ephric mesenchyme (MM), which along with the ureteric bud (UB), is responsible for the mutually induc

34 ulture in which the MM is separated from the ureteric bud (UB), the natural inducer, can be used as a

35 cting system of the kidney, derived from the ureteric bud (UB), undergoes repetitive bifid branching

36 Defects in the growth and branching of the ureteric bud (UB), which gives rise to the collecting sy

37 cting system of the kidney develops from the ureteric bud (UB), which undergoes branching morphogenes

38 gene was inactivated in the developing mouse ureteric bud (UB).

39 develops from branching morphogenesis of the ureteric bud (UB).

40 ation of Dchs1 also reduces branching of the ureteric bud and impairs differentiation of ureteric bud

41 Nestin was not detected in ureteric bud and its derivatives throughout renal develo

42 equired for normal morphogenesis of both the ureteric bud and metanephric mesenchyme-derived structur

43 DSTYK colocalizes with FGF receptors in the ureteric bud and metanephric mesenchyme.

44 derived through the mutual induction of the ureteric bud and metanephric mesoderm, whereas the malpi

45 esult of reciprocal interactions between the ureteric bud and the blastema.

46 inductive interactions between the embryonic ureteric bud and the metanephric mesenchyme are the basi

47 genesis depend on an interaction between the ureteric bud and the metanephric mesenchyme.

48 of which function in the interaction of the ureteric bud and the metanephric mesenchyme.

49 e are expressed at stage E12.5 in the murine ureteric bud and/or metanephric mesenchyme.

50 nvasion of the metanephric mesenchyme by the ureteric bud at an early stage of kidney development.

51 nt in mutant mesenchyme dorsal to the mutant ureteric bud at embryonic day (E) 10.5, while mutant ure

52 Specifically, as the ureteric bud bifurcates, endothelia form across the bifu

53 t reductions were measured in the numbers of ureteric bud branch points and tips, as well as in the t

54 At the same time, the tips of the ureteric bud branches lost the typical appearance of an

55 In the RUB1 cells and ureteric bud branches of embryonic kidney, colocalizatio

56 ddition, DPP and annexin 2 colocalize in the ureteric bud branches of embryonic metanephric kidney.

57 The kidney develops by cycles of ureteric bud branching and nephron formation.

58 This is associated with reductions in ureteric bud branching and nephron number.

59 ved neurotrophic factor, a crucial factor in ureteric bud branching and subsequent nephron developmen

60 13.5 to 15.5 mice grow in size and continue ureteric bud branching and tubule formation over a 4- to

61 Ret receptor tyrosine kinase is crucial for ureteric bud branching morphogenesis during kidney devel

62 of embryonic kidneys with HDACi impairs the ureteric bud branching morphogenesis program and provoke

63 1, and interleukin-11 significantly enhanced ureteric bud branching morphogenesis.

64 re) resulted in no apparent abnormalities in ureteric bud branching or in distal ureter maturation, a

65 ized by urinary tract abnormalities, reduced ureteric bud branching, and delayed disconnection of the

66 In the kidney, GATA3 is essential for ureteric bud branching, and mice without it fail to deve

67 Sema3a acts as a negative regulator of ureteric bud branching, but its function in glomerular d

68 t that is important for glomerulogenesis and ureteric bud branching.

69 ed to study individual cell behaviors during ureteric bud branching.

70 e renal hypoplasia, associated with impaired ureteric bud branching.

71 e, transgenic overexpression of Wnt9b in the ureteric bud causes reduced branching in multiple founde

72 several genetic labeling methods to observe ureteric bud cell behaviors in developing mouse kidneys.

73 PP binds to annexin 2 and 6 present in a rat ureteric bud cell line (RUB1).

74 of a dominant-negative RA receptor in mouse ureteric bud cells abolishes Ret expression and Ret-depe

75 rsely, we find that RA-receptor signaling in ureteric bud cells depends mainly on RA generated in nea

76 se around populations of cap mesenchymal and ureteric bud cells in a cyclical, predictable manner.

77 is, indicating that RA-receptor signaling in ureteric bud cells is crucial for renal development.

78 RA signaling between stromal mesenchyme and ureteric bud cells that regulates Ret expression both du

79 ryonic stem cells can be differentiated into ureteric bud cells.

80 ferent transcripts that were enriched in the ureteric bud compared with metanephric mesenchyme and pr

81 tified several genes whose expression in the ureteric bud depends on Etv4 and Etv5, including Cxcr4,

82 trast, mice lacking talins in the developing ureteric bud developed kidney agenesis and collecting du

83 ype II receptor in mice at the initiation of ureteric bud development.

84 Troy is expressed in the ureteric bud during embryonic development.

85 F and controls outgrowth and invasion of the ureteric bud epithelia in the developing kidney.

86 renal medulla are derived from Pax2-positive ureteric bud epithelia that continue to express Pax2 and

87 cate a novel role of Wnt7b signaling and the ureteric bud epithelium in renal medullary capillary dev

88 acts via receptors on the Wolffian duct and ureteric bud epithelium.

89 ix1, but not Six2, Sall1, or Pax2, while the ureteric bud expresses Ret and Pax2 normally.

90 ession and Ret-dependent functions including ureteric bud formation and branching morphogenesis, indi

91 nchyme and are required for the induction of ureteric bud formation and its subsequent branching morp

92 derived neurotrophic factor (GDNF) initiates ureteric bud formation and promotes subsequent branching

93 ls that regulates Ret expression both during ureteric bud formation and within the developing collect

94 ng the metanephric blastema and inducing the ureteric bud formation but not for its normal branching.

95 Although ureteric bud formation is normal in Vangl2(Lp/Lp) embryo

96 n the Wolffian duct epithelium contribute to ureteric bud formation.

97 Branching morphogenesis of the epithelial ureteric bud forms the renal collecting duct system and

98 In mouse Sall1 mutants, the ureteric bud grows out and invades the metanephric mesen

99 tors frizzled (Fz) 4 and Fz8 lead to reduced ureteric bud growth and a reduction in kidney size, a ph

100 Ureteric bud growth and branching requires GDNF signalin

101 are excluded from the tips of the branching ureteric bud in chimeric kidneys.

102 ructures except those that were derived from ureteric bud in embryonic kidney through adult kidney.

103 ng cells can functionally substitute for the ureteric bud in these interactions.

104 To look for ureteric bud induction defects in young embryos, we asse

105 ng axis in MM development and regulating the ureteric bud induction site are incompletely understood.

106 nce of alpha8beta1 integrin, invasion by the ureteric bud into the metanephric mesenchyme is inhibite

107 in the metanephric mesenchyme at the time of ureteric bud invasion.

108 The ureteric bud is an epithelial tube that undergoes branch

109 e effect and showed significant increases in ureteric bud length and area.

110 nch points and tips, as well as in the total ureteric bud length, volume and area, while significant

111 t of a developmental regulatory system and a ureteric bud marker.

112 lopment of a normal kidney depends on proper ureteric bud morphogenesis, the cellular events underlyi

113 are together important for Wolffian duct and ureteric bud morphogenesis.

114 evelopment of metanephric kidney begins with ureteric bud outgrowth from the Wolffian duct (WD).

115 receptor on the Wolffian duct that regulates ureteric bud outgrowth in the development of a functiona

116 Altered ureteric bud outgrowth was identified in Lzts2 null embr

117 reteric bud was smaller and branching of the ureteric bud reduced.

118 signals that control gene expression at the ureteric bud tip are not well understood.

119 ureteric bud and impairs differentiation of ureteric bud tip cells into trunk cells.

120 ce the movements and divisions of individual ureteric bud tip cells.

121 omprehensive gene expression analysis of the ureteric bud tip to identify bioactive molecules.

122 anephric mesenchyme are required to modulate ureteric bud tip Wnt patterning in order to initiate bra

123 he Wolffian duct that give rise to the first ureteric bud tip, initiating kidney development.

124 inductive interactions and feedback between ureteric bud tips and the surrounding mesenchyme.

125 al. identify a peculiar mitotic behavior in ureteric bud tips whereby dividing cells leave the epith

126 ls, which are abnormally arranged around the ureteric bud tips, and impairment of nephron morphogenes

127 ling promotes directed cell movements in the ureteric bud tips, and suggest a model in which these ce

128 xin2 are ectopically expressed in the mutant ureteric bud tips, suggesting that upregulated canonical

129 m the surrounding mesenchyme to cells at the ureteric bud tips, via the Ret receptor tyrosine kinase

130 ggregation of SIX2-positive cells around the ureteric bud tips.

131 ion of Bmp4 in mesenchymal cells near mutant ureteric bud tips.

132 positively regulated by Ret signaling in the ureteric bud tips.

133 me and nephron, but were underrepresented in ureteric bud tips.

134 terized by both increased number and size of ureteric bud tips.

135 This engineered ureteric bud tissue also organized the mesenchyme into s

136 e embryonic stem cells to differentiate into ureteric bud tissue.

137 bud at embryonic day (E) 10.5, while mutant ureteric bud tissues undergo high rates of apoptosis by

138 ch represses Ret levels and signaling in the ureteric bud to ensure normal ureteric morphogenesis.

139 last growth factor receptor 2 (Fgfr2) in the ureteric bud using a Hoxb7cre line (Fgfr2(UB-/-)) develo

140 inus at embryonic day 10.5, formation of the ureteric bud was delayed, the ureteric bud was smaller a

141 rmation of the ureteric bud was delayed, the ureteric bud was smaller and branching of the ureteric b

142 into Fras1(bl/bl) mice, thereby reducing the ureteric bud's expression of this anti-branching molecul

143 ation, regions of mutant mesenchyme near the ureteric bud(s) express Eya1 and Six1, but not Six2, Sal

144 While the ureteric bud(s) initiates, it does not elongate or branc

145 entiated MM (unlike the upper portion of the ureteric bud) or more differentiated metanephric kidney.

146 Ret knockout mice do not form the ureteric bud, a caudal outgrowth of the Wolffian duct an

147 timized method for making a branch-competent ureteric bud, a tissue fundamental to kidney development

148 Here, we report that nephric duct, ureteric bud, and collecting duct epithelia express high

149 itors (NP), early epithelial NP derivatives, ureteric bud, and cortical stroma; p-Creb was present in

150 etween the Wolffian duct, its derivative the ureteric bud, and their adjacent mesenchymes.

151 niche, and Fgf9, secreted from the adjacent ureteric bud, are necessary and sufficient to maintain p

152 of the Wt1 gene eliminates outgrowth of the ureteric bud, but Gdnf has been identified as a target o

153 nsistently, TfR1 provided transferrin to the ureteric bud, but not to the capsule or the stroma.

154 While SCF is restricted to the ureteric bud, c-kit-positive cells are located within th

155 ix molecule FRAS1, normally expressed by the ureteric bud, leads to bilateral renal agenesis in human

156 mesoderm, nephric duct, mesonephric tubules, ureteric bud, pretubular aggregates and their derivative

157 distribution in the caudal Wolffian duct and ureteric bud, similar to Ret(-/-) cells, revealing a cel

158 wever, once Gdnf stimulates branching of the ureteric bud, the Flk1-dependent angioblast signal is no

159 d cell behavior in the branching tips of the ureteric bud, which we term "mitosis-associated cell dis

160 he newly formed epithelial bud, known as the ureteric bud, will continue to branch ultimately differe

161 Branching of ureteric bud-derived epithelial tubes is a key morphogen

162 These data suggest that ureteric bud-derived SCF elicits growth-promoting effect

163 elopment from metanephric mesenchyme but not ureteric bud.

164 pression of a stabilized beta-catenin in the ureteric bud.

165 pends on precise control of branching of the ureteric bud.

166 that later emerges as the tip of the primary ureteric bud.

167 ffect more mature structures or cells in the ureteric bud.

168 ric mesenchyme to inductive signals from the ureteric bud.

169 ing the inductive signals emanating from the ureteric bud.

170 d as simply the non-branching portion of the ureteric bud.

171 GDNF supplied only by the Wolffian duct and ureteric bud.

172 in turn elicits an inductive signal from the ureteric bud.

173 embryonic circulation form a ring around the ureteric bud.

174 rentiate in response to WNT signals from the ureteric bud.

175 nesis and Vangl2 is known to be expressed in ureteric bud/collecting duct and metanephric mesenchymal

176 ecting ducts: galectin-3 is expressed in the ureteric bud/collecting duct lineage during nephrogenesi

177 s of the Wolffian ducts and the duct derived ureteric bud/collecting duct system in an undifferentiat

178 rucial for controlling Ret expression in the ureteric bud; however, the mechanism by which retinoid-s

179 pment in Fat4(-/-) kidneys revealed abnormal ureteric budding and excessive RET signaling.

180 The ureteric buds (UBs) in mutants emerge as doublets from t

181 MM leads to kidneys with cranially displaced ureteric buds along the Wolffian duct or duplex ureters.

182 demonstrated that ErbB4 is expressed in the ureteric buds and developing tubules of embryonic rat ki

183 Inductive interactions between the branching ureteric buds and the metanephric mesenchyme lead to mes

184 rtex of ex fetu kidney rudiments, engineered ureteric buds branched and induced nephron formation; wh

185 Engineered ureteric buds branched in three-dimensional culture and

186 We characterized isolated engineered ureteric buds differentiated from embryonic stem cells i

187 sexpression of GDNF in the Wolffian duct and ureteric buds resulted in formation of multiple, ectopic

188 ds to a virtual absence of MM and unbranched ureteric buds that are occasionally duplex.

189 ic kidneys that were caused by supernumerary ureteric buds that fail to separate from the wolffian du

190 Mice lacking this tyrosine grow ectopic ureteric buds that will ultimately form supernumerary ki

191 resumably enables the nephronectin-deficient ureteric buds to invade the metanephric mesenchyme and b

192 es branching of cultured wildtype and mutant ureteric buds, and achieves similar branching patterns w

193 In genetically mosaic mouse ureteric buds, competition between phenotypically mutant

194 efects but had cranially displaced or duplex ureteric buds, probably as a result of decreased Bmp4 ex

195 one from mouse E12.5 and one from rat E13.5 ureteric buds.

196 odality for the treatment of renal and upper ureteric calculi.

197 dney mRNA in mice with Ilk deficiency in the ureteric cell lineage.

198 dentified genes that are regulated by Ilk in ureteric cells using a whole-genome expression analysis

199 ailable to the urologist in the treatment of ureteric colic as well as the advantages and disadvantag

200 The management of ureteric colic has changed significantly over the past t

201 e passage for people managed expectantly for ureteric colic, but emphasised the need for high-quality

202 weeks for patients with expectantly managed ureteric colic.

203 We find that (1) non-UPEC do not affect ureteric contractility, (2) impairment of contractility

204 96 and 536) can subvert this role and reduce ureteric contractility.

205 r signaling (Frs2alpha(UB-/-)) leads to mild ureteric defects.

206 Mice with ureteric deletion of both Fgfr2 and Frs2alpha (Fgfr2/Frs

207 ha, compound mutant mice were generated with ureteric deletion of Fgfr1 and with Fgfr2(LR/LR) point m

208 severe ureteric branching defects; however, ureteric deletion of fibroblast growth factor receptor s

209 s required for early branching events of the ureteric duct that occur prior to the onset of nephrogen

210 abnormality of early branching events of the ureteric duct.

211 e Esrrg protein is detected throughout early ureteric ducts as cytoplasmic/sub-membranous staining; w

212 een three lineages (stromal, mesenchymal and ureteric) ensures correct nephron progenitor self-renewa

213 nificant in vitro plasticity and can adopt a ureteric epithelial tip identity when isolated and cultu

214 amina propria cells directly adjacent to the ureteric epithelium and differentiated smooth muscle cel

215 key nephrogenic progenitor populations: the ureteric epithelium and the cap mesenchyme.

216 x reciprocal tissue interactions between the ureteric epithelium and the mesenchyme.

217 "Induced" ureteric epithelium cultures can be cryopreserved, seria

218 ional distinction between distal nephron and ureteric epithelium in human fetal kidney, we show here

219 These include the ureteric epithelium of the collecting duct network, the

220 nitors contribute to the nephrons versus the ureteric epithelium of the kidney.

221 ids contain distal nephron epithelium and no ureteric epithelium, this distal nephron segment alone d

222 ly, the linked BAC confers expression in the ureteric epithelium, whereas sequences within any of the

223 transcriptionally active beta-catenin in the ureteric epithelium.

224 tain nephrons or pattern specifically to the ureteric epithelium.

225 system, which originates from the branching ureteric epithelium.

226 podocytes, proximal and distal nephron, and ureteric epithelium.

227 ssues, suggesting a mechanism underlying the ureteric induction and VUR phenotypes.

228 sites into the bladder, consistent with the ureteric induction defects.

229 The vesico-ureteric junction (VUJ) forms through a complex developm

230 Pelvi-ureteric junction obstruction is mostly detected prenata

231 rosis and failure to develop a patent pelvic-ureteric junction.

232 We observed 2 UC (ureteric leak and stenosis), 8 urinary tract infections,

233 gfr2 and Frs2alpha have crucial roles in the ureteric lineage, they appear to act separately and addi

234 ationship between Fgfr2 and Frs2alpha in the ureteric lineage.

235 ntial for developmental specification of the ureteric mesenchyme and ureteric smooth muscle cells.

236 2(LR/LR) mice also had subsequent defects in ureteric morphogenesis, including dilated, hyperprolifer

237 gnaling in the ureteric bud to ensure normal ureteric morphogenesis.

238 s in vitro and in vivo in a mouse Unilateral Ureteric Obstruction (UUO) model.

239 ished a murine model of fibrosis (unilateral ureteric obstruction (UUO)).

240 Sdc4-null mice were subjected to unilateral ureteric obstruction and aristolochic acid nephropathy (

241 n, injury, and fibrosis following unilateral ureteric obstruction in mice.

242 e used in the murine, reversible, unilateral ureteric obstruction model to dissect the transcriptomic

243 ild-type C57BL/6 mice (n=14), and unilateral ureteric obstruction was performed later to induce renal

244 Following unilateral ureteric obstruction, PAR2-deficient mice displayed redu

245 In a murine model with unilateral ureteric obstruction, pretreatment with dasatinib signif

246 el of progressive renal fibrosis (unilateral ureteric obstruction, UUO), and absence of galectin-3 pr

247 ent (EAS) could be used to bypass a complete ureteric obstruction.

248 model of renal fibrosis caused by unilateral ureteric obstruction.

249 collecting system to severe injury following ureteric obstruction.

250 nterstitial fibrosis in mice with unilateral ureteric obstruction.

251 ry models: folate nephropathy and unilateral ureteric obstruction.

252 travesicular fluid-filled mass near the left ureteric orifice ( Fig 5 ).

253 travesicular fluid-filled mass near the left ureteric orifice.

254 Surgeon-controlled robotic management of ureteric pathology involving all parts of the ureter wit

255 y has an expanding role in the management of ureteric pathology.

256 period a little slower than that of natural ureteric peristalsis.

257 ities in the ureter led to severely impaired ureteric peristalsis.

258 ion to some of the drawbacks associated with ureteric reconstruction.

259 and urinary tract (CAKUT), including vesico-ureteric reflux (VUR), are major causes of ESRD in child

260 or bladder augmentation, colposuspension and ureteric reimplantation are reviewed.

261 on of a bulking agent and minimally invasive ureteric reimplantation.

262 ureteric volume and surface area and longer ureteric segments than control mice.

263 nascent ureteric urothelium and ending with ureteric smooth muscle cell differentiation, with Tshz3

264 specification of the ureteric mesenchyme and ureteric smooth muscle cells.

265 gulates differentiation and proliferation of ureteric smooth muscle progenitor cells during murine ki

266 Mutation in nephrons, ureteric smooth muscle, and mesenchyme surrounding the l

267 Moreover, in ureteric smooth muscle, the circular smooth muscle cells

268 All ureteric stenoses were treated by surgical reconstructio

269 ologic complications (MUCs: urinary leak and ureteric stenosis [US]) in kidney transplants procured f

270 survival after percutaneous ureteroplasty of ureteric stenosis after renal transplantation and to com

271 ently reported all-cause adverse events were ureteric stenosis in 31 (44%) of 71 patients, urinary tr

272 ith percutaneous ureteroplasty of transplant ureteric stenosis were not significantly worse than thos

273 plant recipients who developed postoperative ureteric stenosis.

274 of transplant recipients with no history of ureteric stenosis.

275 mes to those of patients who did not develop ureteric stenosis.

276 managed surgically or by means of long-term ureteric stent placement.

277 n ureteroneocystostomy over a double pigtail ureteric stent was performed in all transplants, and ure

278 Prophylactic ureteric stenting in renal transplantation reduces major

279 stent was performed in all transplants, and ureteric stents were removed after approximately 6 weeks

280 undergoing expectant management for a single ureteric stone identified by CT at 24 UK hospitals.

281 ve lithotripsy (SWL) treatment for renal and ureteric stones.

282 s had renal colic and were suspected to have ureteric stones; they showed suspected areas of abnormal

283 ular, ureteropelvic junction obstruction and ureteric stricture disease.

284 Ureteric stricture is the most common urological complic

285 ovel EAS system in a patient with transplant ureteric stricture when antegrade stent placement or sur

286 ing, distortion of renal calyces and pelvic, ureteric strictures, stenosis, urinary outflow tract obs

287 d beta-catenin are elevated in the nuclei of ureteric, stromal, and mesenchymal cells within dysplast

288 tosis-associated cell dispersal." Premitotic ureteric tip cells delaminate from the epithelium and di

289 Six genes with expression in ureteric tip cells, including Wnt11, were downregulated,

290 Given the high rate of cell division in ureteric tips, this cellular behavior causes extensive e

291 WNT11 and GDNF permits the dense packing of ureteric tips.

292 Analysis of obstructive ureteric tissue resected from children with congenital i

293 ltured embryonic kidneys, without increasing ureteric tree branching, and promoted mesenchymal-to-epi

294 s work showed that Wnt7b is expressed in the ureteric trunk epithelium and activates canonical Wnt si

295 ression of Ret and its downstream targets in ureteric trunks, and exhibited upregulation of Ret/Etv4/

296 Furthermore, dysplastic ureteric tubules that were surrounded by high levels of

297 dney requires reciprocal signaling among the ureteric tubules, cap mesenchyme and surrounding stromal

298 with sonic hedgehog secreted by the nascent ureteric urothelium and ending with ureteric smooth musc

299 A ureteric-vaginal fistula developed 2 weeks after uterus

300 Furthermore, these mice had decreased ureteric volume and surface area and longer ureteric seg