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1 term graft loss independent of histology and urinary albumin.
2 nt the development of excessive excretion of urinary albumin.
3 f the controls and was detected earlier than urinary albumin.
4 n of CKD than the current clinical standard, urinary albumin.
7 C was measured by using a nephelometer, and urinary albumin and creatinine were measured from a spot
9 rs receptor-mediated endocytosis, increasing urinary albumin and glucose excretion and impairing weig
11 es and contributing to enhanced excretion of urinary albumin and recruitment/activation of inflammato
13 d pressure, kidney weight/body weight ratio, urinary albumin, and urinary thiobarbituric acid-reactin
14 clude the albumin:creatinine ratio (ACR) and urinary albumin concentration (UAC) obtained from a sing
15 hin-pair coefficients of variation (CVs) for urinary albumin concentration and other urinary variable
18 e, diabetes, serum creatinine concentration, urinary albumin concentration, previous cardiovascular e
19 ab38 knockout and control rats showed higher urinary albumin concentrations and reduced amounts of me
21 blood glucose, post prandial blood glucose, urinary albumin creatine ratio, erythrocyte sedimentatio
22 protein-cholesterol (LDL-C) (p = 0.0009) and urinary albumin creatinine ratio (p < 0.0001) improved.
23 cal Evaluation) trial in patients with T2DM, urinary albumin-creatinine ratio >300 mg/g, and estimate
25 interval, 1.21-1.55; P<0.001) and increased urinary albumin-creatinine ratio (P<0.001) were identifi
27 icipants with type 2 diabetes mellitus and a urinary albumin-creatinine ratio (UACR) >=150 mg/g (17.0
28 mg/dl, eGFR >=25 ml/min per 1.73 m(2), and a urinary albumin-creatinine ratio (UACR) 30-5000 mg/g to
30 sortium provided GWAS summary data for eGFR, urinary albumin-creatinine ratio (UACR), BUN, and serum
31 th CKD (eGFR >=20 ml/min per 1.73 m(2) and a urinary albumin-creatinine ratio of 150-5000 mg/g) were
33 x, estimated glomerular filtration rate, and urinary albumin-creatinine ratio up to 10 y posttranspla
35 l indices of central adiposity and increased urinary albumin-creatinine ratio, which enable further r
36 ) (1.1, 1.4) versus 1.2 (1.0, 1.4)), and AUC urinary albumin-creatinine ratios 69 (40, 112) versus 58
37 oglobin A1c >=6.5% or self-report and CKD by urinary albumin/creatinine >=30 mg/g or glomerular filtr
38 GFR 20-44 or 45-59 ml/min per 1.73 m(2) with urinary albumin/creatinine (ACR) >=50 mg/g and serum bic
39 h sCrry expression was maximally stimulated (urinary albumin/creatinine = 12.4 +/- 4.3 and 36.9 +/- 7
41 e, known diabetes duration, waist/hip ratio, urinary albumin/creatinine ratio (ACR) and fasting C-pep
42 beta=-0.21 per 1-SD increment; P=0.005), and urinary albumin/creatinine ratio (beta=-0.15 per 1-SD in
43 o, 1.39 per 1-SD increment; P=0.002) and log-urinary albumin/creatinine ratio (hazard ratio, 1.31 per
44 2.3%) with moderately increased albuminuria (urinary albumin/creatinine ratio [UACR] 30-300 mg/g) and
46 smoking, type 2 diabetes, higher body size, urinary albumin/creatinine ratio of >=3 mg/mmol, and hig
47 , and endothelial function (homocysteine and urinary albumin/creatinine ratio) measured at the sixth
48 Further adjustment for serum cystatin C, urinary albumin/creatinine ratio, and arterial elasticit
49 ce exhibited higher systolic blood pressure, urinary albumin/creatinine ratio, RPTC apoptosis and uri
50 elevated systolic blood pressure, increased urinary albumin/creatinine ratio, tubulo-interstitial fi
51 sed mice had chronic renal injury, increased urinary albumin/creatinine ratios, and increased tissue
52 pulse pressure, serum fibrinogen levels and urinary albumin/creatinine ratios, and with stepwise inc
53 ultrastructural renal lesions, and measured urinary albumin/creatinine ratios, tissue oxidative stre
54 enalapril attenuated CS-induced increases in urinary albumin/creatinine ratios, tissue oxidative stre
60 ciation between treatment effects on 6-month urinary albumin:creatinine ratio (UACR) change and the e
61 ed glomerular filtration rate (eGFR) and the urinary albumin:creatinine ratio (uACR) were measured at
62 ar pattern was observed when we adjusted for urinary albumin:creatinine ratio in place of serum creat
63 ney disease and no history of gout who had a urinary albumin:creatinine ratio of 265 or higher (with
65 hy Dietary Pattern was associated with lower urinary albumin:creatinine ratios, common carotid intima
67 ulated the contribution of RBP4, prealbumin, urinary albumin, eGFR, and CRP to these associations as
68 s included progression to overt proteinuria (urinary albumin excretion > or = 300 mg/d) in half of th
70 d to a normoalbuminuric or macroalbuminuric (urinary albumin excretion <30 mg/24 hours and >300 mg/24
71 ient sFlt-1 mice also showed markedly higher urinary albumin excretion (467+/-74 versus 174+/-23 mug/
72 o -0.4; P=0.003) but positively with 24-hour urinary albumin excretion (beta=0.11; 95% CI, 0.01 to 0.
73 nuria, indicated by repeated measurements of urinary albumin excretion (estimated on the basis of alb
74 btained and are reliable indices of elevated urinary albumin excretion (microalbuminuria) in IDDM.
75 ase-line blood pressure predicted increasing urinary albumin excretion (P=0.006), and higher base-lin
83 Here, we examined whether higher levels of urinary albumin excretion among African Americans contri
84 n in 13 type 1 diabetic subjects with normal urinary albumin excretion and 13 healthy volunteers.
85 brisentan attenuated the increases in BP and urinary albumin excretion and ameliorated endotheliosis
86 hat there is an association between elevated urinary albumin excretion and apolipoprotein B fraction
87 red the glomerular filtration rate (GFR) and urinary albumin excretion and assessed the prevalence of
88 ly overt manifestations, including increased urinary albumin excretion and decreased glomerular filtr
89 ssessed cross-sectional associations between urinary albumin excretion and dietary patterns and intak
90 iation was lost after further adjustment for urinary albumin excretion and eGFR [HR:1.15 (95% CI, 0.8
91 the frequency of a significant reduction in urinary albumin excretion and factors affecting such red
92 treatment with CTLA4-Ig prevented increased urinary albumin excretion and improved kidney pathology
93 /-1.2 vs 7.9+/-0.6 micromol/L p<0.01), while urinary albumin excretion and mesangial expansion were r
94 delay the onset and progression of increased urinary albumin excretion and reduced GFR in patients wi
96 sion, extracellular matrix accumulation, and urinary albumin excretion as well as NOX4 protein expres
98 ted that treatment with sTbetaRII.Fc reduced urinary albumin excretion by 36% at 4 weeks, 59% at 8 we
99 ence is accumulating that early increases in urinary albumin excretion could be predictive of adolesc
101 with type 1 diabetes indicates that elevated urinary albumin excretion does not imply inexorably prog
102 Decreased mGFR, metabolic syndrome, and urinary albumin excretion emerged as strong predictors o
105 ich was defined as a 50 percent reduction in urinary albumin excretion from one two-year period to th
107 d statistical significance with variation in urinary albumin excretion in family members with type 2
115 uria may occur in diabetes and how increased urinary albumin excretion may be indicative of CV risk.
117 in excretion (P=0.006), and higher base-line urinary albumin excretion predicted a decline in the glo
120 correlation between plasma PK levels and the urinary albumin excretion rate (AER) was also observed (
123 survival studies in NIDDM, microalbuminuria (urinary albumin excretion rate 20-200 microg/min) predic
126 to high-density lipoprotein cholesterol, and urinary albumin excretion rate and with the mean glycosy
128 poproteins, glycosylated hemoglobin, and the urinary albumin excretion rate were measured in a centra
129 t smoking, preexisting CHD, and high initial urinary albumin excretion rate were risk factors for the
130 dex, higher von Willebrand factor levels and urinary albumin excretion rate, hypertension, and smokin
133 gher in type 1 diabetic subjects with normal urinary albumin excretion than in control subjects.
136 -0.57 g per square meter per year, P<0.001); urinary albumin excretion was reduced by 3.77% with the
137 Such modification was also observed when urinary albumin excretion was stratified into normo-, mi
138 sive, nondiabetic individuals, low levels of urinary albumin excretion well below the current microal
139 rular capillary basement membrane width, and urinary albumin excretion were increased in diabetic rat
140 Histologic evidence of glomerular injury and urinary albumin excretion were more pronounced in double
143 xplain, in part, the association of elevated urinary albumin excretion with cardiovascular disease ri
144 protein B fractions modified associations of urinary albumin excretion with incident cardiovascular d
145 termined whether the association of elevated urinary albumin excretion with incident cardiovascular e
146 LDO pod GC-A cKO mice demonstrated increased urinary albumin excretion with marked mesangial expansio
148 tid ultrasound, ankle-brachial pressure, and urinary albumin excretion) and stratified by body mass i
149 nal function (glomerular filtration rate and urinary albumin excretion), and routine biochemistry sho
151 omerular filtration rate, renal plasma flow, urinary albumin excretion, and blood pressure were measu
152 lar filtration rate, serum creatinine level, urinary albumin excretion, and blood pressure; the rates
153 oponin-T, high-sensitive C-reactive protein, urinary albumin excretion, and cystatin-C had similar ri
154 ation of hypertension with serum creatinine, urinary albumin excretion, and ESRD in the United States
155 The rates of decline in the estimated GFR, urinary albumin excretion, and other secondary outcomes
156 imaging, we related arterial stiffness, GFR, urinary albumin excretion, and potential mediators, incl
162 betic Cav2.2(-/-) mice significantly reduced urinary albumin excretion, glomerular hyperfiltration, b
163 00 mg/kg body wt/d) in the drinking water on urinary albumin excretion, glomerular transforming growt
164 anced by lack of both B1R and B2R, including urinary albumin excretion, glomerulosclerosis, glomerula
165 -B-type natriuretic peptide, troponin-T, and urinary albumin excretion, increasing model accuracy to
166 m and long-term benefits of empagliflozin on urinary albumin excretion, irrespective of patients' alb
168 itor, reduced systolic blood pressure (SBP), urinary albumin excretion, segmental sclerosis, podocyte
182 inhibitor type 1), and microvascular damage (urinary albumin excretion; n=2673) to incident AF (n=209
184 bstantially attenuated, but the excretion of urinary albumin factored for creatinine clearance was no
185 s did not respond to nonrenal toxicants, and urinary albumin faithfully reflected alterations in rena
186 These results show that the generation of urinary albumin fragments occurs independently of renal
190 e utility of measuring plasma creatinine and urinary albumin, has been almost entirely focused on the
192 S have suggested that binding of diuretic to urinary albumin is one of the mechanisms that may be ope
194 in diet significantly slowed the increase in urinary albumin level or the decline in glomerular filtr
198 uclear factor-kappaB activity, and increased urinary albumin levels, all of which is similar to chang
199 ose and HbA1c levels, retinopathy, lipid and urinary albumin levels, cardiovascular events, hypoglyce
202 r composite (3.8 vs 3.7, P = .93), or year 5 urinary albumin (median, 7.5 vs 7.4 mg/g of creatinine,
203 increased baseline systolic blood pressure, urinary albumin, plasma creatinine, and Indian-Asian eth
204 ea under the curve [AUC] 0.93) compared with urinary albumin routinely used to determine the diagnosi
205 Patients with glomerular lesions had higher urinary albumin than those with normal histology, while
206 s a critical mechanism for excessive loss of urinary albumin that eventuates in kidney fibrosis.
208 g/dL; 95% CI, -0.7 to -0.07 mg/dL; P = .02), urinary albumin to creatinine ratio (-119.4 mg/g; 95% CI
211 he prevalence and prognostic value of a spot urinary albumin to creatinine ratio (UACR) in patients w
212 of baseline eGFR (<60 vs 60 mL/min/1.73 m2), urinary albumin to creatinine ratio (UACR; <30 vs 30 mg/
213 5 years with proteinuria (first morning void urinary albumin to creatinine ratio [UACR] 100-3000 mg/g
214 r, these mice showed a four-fold increase in urinary albumin to creatinine ratio and development of f
215 gression, on the basis of either eGFR or the urinary albumin to creatinine ratio, in MESA participant
217 +/- 1, mutant versus control), albuminuria (urinary albumin to creatinine ratio: 23 +/- 15 versus 0.
218 ities of urinary trefoil factor 3 (TFF3) and urinary albumin to detect acute renal tubular injury hav
219 In the subgroup of patients with baseline urinary albumin-to-creatinine ratio >/=30 mg/g, urinary
220 1.73 m(2) and macroalbuminuria defined by a urinary albumin-to-creatinine ratio >300 mg/g, were rand
224 (1.40), C-reactive protein level (1.39), the urinary albumin-to-creatinine ratio (1.22), homocysteine
225 ifferences in Stroke (REGARDS) study who had urinary albumin-to-creatinine ratio (ACR) and estimated
226 L/min/1.73 m2, 15% had diabetes and 8.4% had urinary albumin-to-creatinine ratio (ACR) available (med
227 lar filtration rate (eGFR(cys)) and measured urinary albumin-to-creatinine ratio (ACR) in 10 328 men
228 We examined race-stratified associations of urinary albumin-to-creatinine ratio (ACR) in 2 groups: (
230 ing pairs, as well as the quantitative trait urinary albumin-to-creatinine ratio (ACR), were performe
231 imated glomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio (ACR), with cancer i
233 diet (food-frequency questionnaire) and the urinary albumin-to-creatinine ratio (ACR; spot urine col
235 genetic underpinnings with the exception of urinary albumin-to-creatinine ratio (Rg = 0.64; SE = 0.2
236 s were adult patients with CKD, defined as a urinary albumin-to-creatinine ratio (UACR) 200-5000 mg/g
237 GFR-associated SNPs for association with the urinary albumin-to-creatinine ratio (UACR) and albuminur
238 icoid receptor antagonists (MRAs) reduce the urinary albumin-to-creatinine ratio (UACR) and confer ki
239 mplitude, while nephropathy was evaluated by urinary albumin-to-creatinine ratio (UACR) and eGFR.
243 nuous positive airway pressure (CPAP) on the urinary albumin-to-creatinine ratio (UACR) in patients w
244 cts with eGFR >20 ml/min per 1.73 m(2) and a urinary albumin-to-creatinine ratio (UACR) of 100 to 300
245 of 20 mL/min per 1.73 m(2) or greater and a urinary albumin-to-creatinine ratio (UACR) of 150-5000 m
246 age estimated glomerular filtration rate and urinary albumin-to-creatinine ratio (uACR) over 3 months
247 variants in CUBN, encoding cubilin, with the urinary albumin-to-creatinine ratio (UACR) were confirme
248 t, Trf1(Delta/Delta) mice displayed elevated urinary albumin-to-creatinine ratio (UACR), associated w
249 per day) to patients with type 2 diabetes, a urinary albumin-to-creatinine ratio (with albumin measur
250 s than 90 ml per minute per 1.73 m(2) with a urinary albumin-to-creatinine ratio (with albumin measur
253 ration rate (eGFR) 25-75 mL/min/1.73m(2) and urinary albumin-to-creatinine ratio 200-5000 mg/g (22.6-
255 es, with eGFR 25-75 ml/min per 1.73 m(2) and urinary albumin-to-creatinine ratio 200-5000 mg/g were r
256 ular filtration rate 25-75 ml/min/1.73 m(2); urinary albumin-to-creatinine ratio 300-5000 mg/g).
257 tion rate [eGFR] of 30-90 mL/min/1.73 m2 and urinary albumin-to-creatinine ratio [UACR] of 200-5000 m
258 r more and under 90 mL/min per 1.73 m(2) and urinary albumin-to-creatinine ratio [UACR] over 50 mg/g)
259 ral pulse wave velocity associated with both urinary albumin-to-creatinine ratio and microalbuminuria
260 tion was stratified on the basis of baseline urinary albumin-to-creatinine ratio and presence of card
261 rular barrier dysfunction assessed using the urinary albumin-to-creatinine ratio and urinary ratio of
262 we identified B-type natriuretic peptide and urinary albumin-to-creatinine ratio as key risk factors
264 nary albumin-to-creatinine ratio >/=30 mg/g, urinary albumin-to-creatinine ratio decreased more with
265 elimination, B-type natriuretic peptide and urinary albumin-to-creatinine ratio emerged as key bioma
269 ior), we observed a significant reduction in urinary albumin-to-creatinine ratio of 15.7% (ratio 0.84
270 r filtration rate 15-59 ml/min/1.73m(2) or a urinary albumin-to-creatinine ratio of 30 mg/g or more)
271 rea, and diabetic retinopathy, or they had a urinary albumin-to-creatinine ratio of 300 to 5000 and a
272 of body-surface area (stage 2 to 4 CKD) or a urinary albumin-to-creatinine ratio of 300 to 5000 and a
274 agliflozin led to a greater reduction in the urinary albumin-to-creatinine ratio than either treatmen
275 (25-47) ml/min per 1.73 m(2), and the median urinary albumin-to-creatinine ratio was 197 (32-895) mg/
276 s 52.9 (29.3) mL/min/1.73 m2, and the median urinary albumin-to-creatinine ratio was 89 mg/g (coeffic
278 respectively) and the mean reduction in the urinary albumin-to-creatinine ratio was greater (between
282 emonstrate that dh404 attenuates functional (urinary albumin-to-creatinine ratio) and structural (mes
285 ohort (R=-0.52 for estimated GFR, R=0.22 for urinary albumin-to-creatinine ratio, and R=0.17 for urin
286 of follow-up, after adjustment for baseline urinary albumin-to-creatinine ratio, eGFR, and Hb1Ac.
287 the change from baseline to 12 weeks in the urinary albumin-to-creatinine ratio, N-terminal pro-B-ty
288 d blood glucose, glomerular filtration rate, urinary albumin-to-creatinine ratio, tubulointerstitial
289 calize gene regions influencing variation in urinary albumin-to-creatinine ratio, we performed a link
294 wave velocity by magnetic resonance imaging; urinary albumin-to-creatinine ratio; and cystatin C were
295 risk factors (age, sex, ethnicity, eGFR, and urinary albumin-to-creatinine ratio; C-index, 0.90; 95%
297 rasentan (7.5 mg/kg/day) for 4 weeks reduced urinary albumin-to-creatinine ratios by 26.0 +/- 6.5% (P
300 F3 protein levels were markedly reduced, and urinary albumin were markedly increased in response to r