ライフサイエンスコーパス: valine

1 ced branched-chain AAs (leucine, isoleucine, valine).

2 1.54 (95% CI 1.28-1.84, p = 4.2 x 10-6) for valine.

3 serine, threonine, tryptophan, tyrosine, and valine.

4 predominant being phenylalanine, lysine and valine.

5 o includes l-methionine, l-isoleucine, and l-valine.

6 f the oxazoline rings were prepared from (S)-valine.

7 HIB) is a catabolic intermediate of the BCAA valine.

8 ino acids were arginine, leucine, lysine and valine.

9 ne, choline compounds, creatine, leucine and valine.

10 ne in the rat enzyme is mutated to the human valine.

11 3-enamine tetramic acid group derived from l-valine.

12 ophobic amino acids isoleucine, leucine, and valine.

13 ferent permutations of glycine, alanine, and valine.

14 he methyl groups of isoleucine, leucine, and valine.

15 1.08]), and no association for isoleucine or valine (0.99 [0.95-1.03] and 1.00 [0.96-1.04], respectiv

16 2.29 (1.31-4.01), leucine 1.80 (1.10-2.96), valine 1.77 (1.07-2.92), tyrosine 2.13 (1.20-3.78), and

17 xy-D-fructose-1-yl) amino acid (amino acid=L-valine (1), L-leucine (2), L-isoleucine (3), L-tryptopha

18 feldt-Jakob disease expressing prion protein valine 129.

19 C terminus, producing three forms ending in valine-175, histidine-177, or serine-178.

20 ation by inducing KPNA1 degradation and that valine-19 in Nsp1beta correlates with the inhibition.

21 wing amino acids are extremely high: 177 for valine, 199 for methionine, 186 for phenylalanine, 118 f

22 alanine (2a), isoleucine (2b), proline (2c), valine (2d), phenylalanine (2e), glycine (2f) and leucin

23 Simultaneously converting alanine 355 and valine 377 of FAR5 to the corresponding FAR8 residues, l

24 We identified two contiguous amino acids, valine-381 and serine-382, located in the C-linker carbo

25 f 11 substitutions of the S1 subsite residue valine 459 in the Plasmodium falciparum aminopeptidase P

26 lorine was found to first react quickly with valine (5.4 x 10(4) M(-1) s(-1)) to form N-monochloroval

27 e two residues to those in Pto (histidine-49/valine-51) did not restore recognition of AvrPto.

28 9-88.5), lysine (54.0-69.8) and valine (59.2-61.8) are the most abundant essential amino

29 Interestingly, dileucine 594/595 and valine 597 residues present in the Ldgp63 C-terminal dom

30 d predict B-rapidly accelerated fibrosarcoma valine 600 (BRAFV600) mutation status with both conventi

31 The valine 66 to methionine (Met) polymorphism within the br

32 er proceeds via the leucine 69 (Leu(69)) and valine 68 (Val(68)) residues.

33 racterize Nva and differentiate it from Val (Valine), a systematic study was conducted using hot elec

34 olution of the genetic code four amino acids-valine, alanine, aspartic acid, and glycine-were coded b

35 tants in which threonine 191 was replaced by valine, alanine, or proline.

36 Individuals with the BDNF Val/Val (valine allele) polymorphism showed better memory perform

37 or replacement of isoleucine with alanine or valine alters the ability of the mutant RdRps to incorpo

38 the FSS13025 strain because of an alanine-to-valine amino acid substitution at residue 188 in NS1.

39 ydroxybutyrate/3-aminoisobutyrate, tyrosine, valine and 3-hydroxyisovalerate exhibited the highest st

40 rms favorable packing between the engineered valine and a target uracil base.

41 sts are derived from the abundant amino acid valine and are prepared in large quantities in four step

42 geometry we can increase ion intensities for valine and by tuning the plasma power we can also select

43 itrate, tyrosine, phenylalanine, isoleucine, valine and glucose were identified and considered as pot

44 ing analyses supported the transformation of valine and isoleucine to isobutylamine and 2-methylbutyl

45 n amino acid degradation (named for leucine, valine and isoleucine) and seed development was limited

46 Together with valine and leucine interdigitation, these cause a dehydr

47 coats, decreased storage reserves, elevated valine and leucine, and reduced germination rates.

48 nding site expand the selectivity to include valine and leucine.

49 A notable exception are valine and lysine tRNAs encoded by three polycistronic p

50 glucose at 120 min, and leucine, isoleucine, valine and proline at 90 and 120 min, whereas infants fe

51 leucine/isoleucine, phenylalanine, tyrosine, valine and proline significantly associated with obesity

52 urther, we demonstrate that co-occurrence of valine and serine at the 31st and 32nd positions in H3VC

53 18 : 0/18 : 1 and inverse associations with valine and serotonin were also observed, although these

54 of key metabolites like proline, asparagine, valine and several flavonoids.

55 ression results revealed a possible role for valine and/or isoleucine in CI tolerance.

56 BCAAs (i.e., isoleucine, leucine, and valine) and their downstream metabolites (i.e., alanine,

57 ected amino acids, FMOC-l-leucine and FMOC-l-valine, and a dipeptide, N-acetyl-l-valyl-l-leucine (N-A

58 ated with a depletion of lipid, cholesterol, valine, and alanine levels, which may provide informativ

59 nched chain amino acids leucine, isoleucine, valine, and alloisoleucine were significantly improved i

60 We find enrichment of glycine, valine, and arginine as both individual amino acids and

61 d with relative overexpression of glutamine, valine, and glycine, and relative suppression of glutama

62 acids alanine, phenylalanine, glutamic acid, valine, and leucine increased in samples exposed to eust

63 BM samples were higher in threonine, serine, valine, and lower in orotic acid and urea.

64 VK (titin domain rich in proline, glutamate, valine, and lysine) region of titin.

65 in (titin region rich in proline, glutamate, valine, and lysine), of the titin springs.

66 lace 29 membrane-facing leucine, isoleucine, valine, and phenylalanine residues in the transmembrane

67 ss-related amino acids (isoleucine, leucine, valine, and proline), sugars, intermediates of the trica

68 d essential amino acids, such as tryptophan, valine, and threonine, were determined in yacon syrup.

69 stidine, phenylalanine, leucine, isoleucine, valine, and tyrosine) were assessed with the use of high

70 d-chain amino acids isoleucine, leucine, and valine are associated with Alzheimer's disease (AD).

71 amino acids (BCAAs) leucine, isoleucine, and valine are elevated in maple syrup urine disease, heart

72 amino acids (BCAAs; leucine, isoleucine and valine) are elevated in the blood of obese, insulin-resi

73 acids (BCAAs; i.e., isoleucine, leucine, and valine) are strongly associated with higher type 2 diabe

74 actobacilli produced leucine, isoleucine and valine as branched chain amino acids when grown on LBG h

75 experiments with asparagine, aspartate, and valine as PKM2 ligands, we examined whether the differen

76 e internally flexible compared to those with valine as the first amino acid.

77 AO, 2013) indicated, isoleucine, leucine and valine as the limiting amino acids.

78 3-HIB), a catabolic intermediate of the BCAA valine, as a new paracrine regulator of trans-endothelia

79 lution of the BCAAs isoleucine, leucine, and valine, as well as 13 other amino acids, including ornit

80 han, tyrosine, alanine, isoleucine, leucine, valine, aspartate, and glutamate) were significantly (P

81 ncentrations of the diabetes-associated BCAA valine at 6 mo independent of the weight change.

82 R-A-A at positions 70-74 in combination with valine at position 11 (11-V) is highly protective in PD,

83 Valine at position 11 also was associated with higher al

84 Patients with RA and valine at position 11 of HLA-DRB1 had the strongest asso

85 nd feet were 48% of noncarriers (150/314) of valine at position 11, 61% of heterozygote carriers (130

86 elic variants, encoding either methionine or valine at position 1316.

87 G2 mutant harboring glutamic acid instead of valine at position 30 (V30E) failed to induce cell death

88 (TTR) with a substitution of methionine for valine at position 30 (V30M).

89 ncode functional (PAV: proline, alanine, and valine at positions 49, 262, and 296, respectively) or n

90 The WT enzyme with valine at residue 172 accumulates a Val(*); mutation of

91 pped (e.g. 'glutamic acid was substituted by valine at residue 6').

92 d the moderate risk RET p.Val804Met (protein valine at residue 804 replaced by methionine) genetic mu

93 P; further, the replacement of leucines with valines at "a" and "d" positions of melittin-heptads dra

94 dium site residue Asn 131 to an alanine or a valine augments constitutive beta-arrestin-mediated sign

95 responding carboxyl and amino termini of (S)-valine-based bis-thiazole and monothiazole derivatives w

96 BCAA: 9.0% +/- 12%; low-BCAA: 9.2% +/- 11%), valine (BCAA: 9.1% +/- 11%; low-BCAA: 12.0% +/- 13%), or

97 beta = -5.2, 95% CI [-8.6; -1.8], p = 0.003; valine: beta = -4.1, 95% CI [-6.9; -1.4], p = 0.003).

98 Valine betaine and glutamine betaine, the latter never r

99 xamined flours, whereas an uncommon betaine, valine betaine, and glutamine betaine were present only

100 Only alanine, glutamate, isoleucine, and valine, but not leucine, were increased in NAFLD-NO subj

101 ne 1768 to aspartic acid and leucine 1331 to valine) by obtaining whole-cell patch clamp recordings i

102 Studies evaluating flux through the valine catabolic pathway in humans should account for th

103 ating with synaptic vulnerability, including valine catabolism and rho signalling pathways.

104 HIBCH is unique to valine catabolism.

105 protease-cleavable linker, maleimido-caproyl-valine-citruline-p-amino-benzyloxy carbonyl (mcVC-PABC).

106 examine the effect of the protease-cleavable valine-citrulline [VC(S)] linker on ADC efficacy.

107 (FucGM1) antibodies using lysosome-cleavable valine-citrulline dipeptide linkers via heterogeneous ly

108 ve hydrolytic linkers or cathepsin-cleavable valine-citrulline peptide linkers.

109 here were only seven primordial amino acids: Valine (coded by GUX [X = U, C, A or G]), alanine (coded

110 rough an individual with the PRNP methionine/valine codon 129 genotype and thus no alteration in viru

111 sium channel Kv1.1 converts an isoleucine to valine codon for amino acid 400, speeding channel recove

112 -MDR1-3HA (a mutant that carries a different valine codon in position 3435).

113 Its replacement with leucine or valine completely abolished activation with paclitaxel w

114 Valine concentrations increased by 40% in response to in

115 hough there is indeed evidence for alternate valine conformers and variable water content.

116 and biochemical data revealed that the DFG-1 valine controlled a noncanonical binding mode in CLK1, p

117 etabolites (e.g. glucose, glycogen, leucine, valine, creatine, carnitine, lactate, nucleosides) were

118 that the major product, MftA*, is a tyramine-valine-cross-linked peptide formed by MftC through two S

119 acetone, ursodeoxycholic acid, tryptophan, L-valine, cycloserine, hypoxanthine, and 4-O-Methylmelleol

120 VARS encodes the only known valine cytoplasmic-localized aminoacyl-tRNA synthetase.

121 e show that disruptions in the mitochondrial valine degradation pathway affect seed development and g

122 ole of two putative mitochondrial enzymes in valine degradation using insertional mutants.

123 HSCs failed to proliferate when cultured in valine-depleted conditions.

124 synthesis of compound 7j (N-aryl-substituted valine derivative) that possesses dual PPARgamma/PPARalp

125 generated in situ from a readily accessible valine-derived aminophenol and a Z- or an E-gamma-substi

126 ctional theory computations, suggesting that valine-derived oxazolidinones would be superior to the p

127 vitro and catalyzes formation of a tyrosine-valine ether cross-link in the protein scaffold.

128 of the protein scaffold, yielding a tyrosine-valine ether cross-link.

129 atalyzes N-oxygenation of the alpha-amine of valine, first to the hydroxylamine and then the nitroso,

130 >G transition that encodes a substitution of valine for a highly conserved methionine (p.Met184Val) i

131 ATTR can result from substitution of valine for isoleucine at codon 122 of the transthyretin

132 in this protein showed that substitution of valine for the phenylalanine residue four residues downs

133 , asparagine, glutamine, proline, serine and valine) for Sudanese food.

134 nts for all reactions in the chlorination of valine, for the first time, using experimental results a

135 , this is hindered by overlapped leucine and valine frequencies.

136 uished electrochemical response to fructosyl valine (FV) which demonstrates a promising application f

137 as the biorecognition element for fructosyl valine (FV), the product of the proteolytic hydrolysis o

138 Histone H3.3 glycine 34 to arginine/valine (G34R/V) mutations drive deadly gliomas and show

139 leucine, leucine, methionine, phenylalanine, valine, GABA, glutamine, alanine, glycine and taurine we

140 ding on pH, opens at either the histidine or valine gate is only partially supported by the simulatio

141 of lactate, choline, or amino acids such as valine, glycine, or glutamate increased with time, where

142 eptide conjugates (CAPs), demonstrating that valine-glycine dipeptide-derived CAP 3 is the most effec

143 mains, which bind the beta-spike of trimeric valine-glycine repeat protein G (VgrG) and are important

144 motifs and genetic linkage to members of the valine-glycine repeat protein G (vgrG) genes.

145 Here, we report that two T6SS encoded valine-glycine repeat protein G (VgrG) paralogs in Agrob

146 linked to hemolysin-coregulated protein and valine-glycine repeat protein G genes from type VI secre

147 Valine-glycine repeat protein G is required for inhibito

148 secretion system (T6SS-5) and its associated valine-glycine repeat protein, VgrG5.

149 +) mouse tumours showed negative choline and valine gradients, but a positive glycine gradient.

150 (BCAAs), including leucine, isoleucine, and valine, has shown potential benefits for the metabolic p

151 b disease infection in a PRNP 129 methionine/valine heterozygous individual has raised the possibilit

152 feldt-Jakob disease in a PRNP 129 methionine/valine heterozygous individual infected via blood transf

153 ture of methionine homozygous and methionine-valine heterozygous over time.

154 Jakob disease (sCJD) VV1-2 type-mixed cases (valine homozygosity at codon 129 of the prion protein, P

155 aline to glycine mutation at codon 176, with valine homozygosity at polymorphic codon 129.

156 prion protein gene (PRNP) from predominantly valine homozygous to a mixed picture of methionine homoz

157 A mutation of isoleucine 335 to valine (I355V) in hSLC2A9 can reduce fructose transport

158 phatic amino acids [isoleucine, leucine, and valine (ILV) clusters] were found to experience strong w

159 of large clusters of isoleucine, leucine and valine (ILV) side chains located in the alpha7(betaalpha

160 the availability of isoleucine, leucine and valine (ILV), and GTP.

161 phatic side chains, isoleucine, leucine, and valine (ILV).

162 nd/or C103 with the beta-branched amino acid valine impairs the structural flexibility of the TMD in

163 line, phenylalanine and tyrosine (instead of valine in B2088) displayed better synergism compared to

164 NAM binding causes displacement of a valine in GluN2A and the resulting steric effects can be

165 These findings indicate a critical role for valine in HSC maintenance and suggest that dietary valin

166 In fact, mutation of this valine in human CYP1B1 to the leucine present in the rat

167 with glycine, alpha-l- or beta-alanine and l-valine in pH 7.0 phosphate buffer at ca. 100 degrees C.

168 At V319C, the equivalent of valine in the conserved Kv proline-valine-proline (PVP)

169 The E11 valine in the distal heme pocket of either the alpha- or

170 d-chain amino acids leucine, isoleucine, and valine in this acute study.

171 rotein deposition from a PRNP 129 methionine/valine individual was inoculated into a panel of wild-ty

172 ge, strain characteristics in the methionine/valine individual were totally consistent with those of

173 acid change at residue 19 from isoleucine to valine induced KPNA1 degradation.

174 Mutation to nonphosphorylatable valine inhibited the Rvs167 interaction, while both S599

175 Here we report that the essential amino acid valine is indispensable for the proliferation and mainte

176 Although valine is similarly hydrophobic to leucine and phenylala

177 The method, which is referred to as VILMHA (valine isoleucine leucine methyl hydrogen analysis), was

178 spectively) or non-functional (AVI: alanine, valine, isoleucine at positions 49, 262, and 296, respec

179 Serum values for a-amino-butyric acid, valine, isoleucine, leucine, tyrosine, phenylalanine, or

180 n obtained by comparing the peak area of the valine/isoleucine/leucine methyl groups to an external,

181 l-isoleucine, l-valine, l-aspartic and ubiquitin carboxyl-terminal hydro

182 Branched-chain amino acid (BCAA; valine, leucine and isoleucine) supplementation is often

183 hippo signaling in normal vs primary HGSOC; valine, leucine, and isoleucine degradation and endocyto

184 ringent set of aliphatic side chains such as valine, leucine, and isoleucine of putative substrates.

185 Branched-chain amino acids (BCAAs, i.e., valine, leucine, and isoleucine) function as nitrogen do

186 serum levels of branched-chain amino acids (valine, leucine, and isoleucine), aromatic amino acids (

187 s in four metabolism pathways: beta-alanine; valine, leucine, iso-leucine; aminoacyl-tRNA; and alanin

188 lete pathways for biosynthesis of histidine, valine, leucine, isoleucine, lysine and proline pre-dete

189 ignificant differences for some metabolites (valine, leucine, isoleucine, proline, and malic acid).

190 The serum levels of valine, leucine, isoleucine, tyrosine, and phenylalanine

191 s are tolerated including those for alanine, valine, leucine, methionine, lysine, phenylalanine, tyro

192 ino aldehydes derived from glycine, alanine, valine, leucine, phenylalanine, isoleucine, serine, tryp

193 had significant changes in the metabolism of valine/leucine/isoleucine; the jejunum, skeletal muscle,

194 vitreous the amino acids implicated in MSUD (Valine, Leukine Isoleukine), were within normal range.

195 he metabolism of branched chain amino-acids (Valine, Leukine, Isoleukine).

196 and one SNP associated with both leucine and valine levels at genome-wide significance.

197 o 48.72 (36.28-64.84) microM (P < .001), and valine levels increased from 122.56 (95.63-140.61) micro

198 Initial compound optimization identified the valine-m-tyrosine-piperazic acid tripeptide (Val-m-Tyr-P

199 t their metabolism requires gluconeogenesis, valine metabolism, the Krebs cycle, the GABA shunt, the

200 ethylpropanoic acid acyl chains derived from valine metabolism.

201 hain amino acid (BCAAs; isoleucine, leucine, valine) metabolism in obesity, insulin resistance, and i

202 Studies of mice suggest that the valine metabolite 3-hydroxyisobutyrate (3-HIB), fibrobla

203 uire supplementation of leucine, isoleucine, valine, methionine, and threonine and modestly require t

204 e structurally variant amino acids, glycine, valine, methionine, phenylalanine and cysteine were exam

205 hboring LRRFIP2, and marked by an isoleucine-valine missense variant in MLH1.

206 cement of regulatory domain methionines with valines (MMVV).

207 exhibiting similar UVPD changes whereas the valine mutation was significantly different.

208 in the patient V(L), only one, a leucine to valine mutation, is responsible for fibril formation.

209 ce revealed that the D166V (Aspartate166 --> Valine) mutation-induced changes in heart morphology and

210 Here, we show that the polymerization of valine-NCA in the presence of fatty acids yields acylate

211 n arginine and oleic acid in the presence of valine-NCA, partitions spontaneously into vesicle membra

212 With glycine, alanine, valine, norvaline, and tert-leucine, HAT occurs from the

213 d by the non-enzymatic glycation of terminal valine of hemoglobin.

214 ine, hydroxyproline, leucine, isoleucine and valine on the negative side of PC1 and porcine gelatin w

215 e number of helix-destabilizing, ss-branched valine or isoleucine residues within the TMD restores no

216 ered when glycine 4864 is replaced by either valine or proline, the former preventing channel opening

217 eties, such as methyl groups of isoleucines, valines, or leucines.

218 on and characterization of this new thiazole-valine peptidomimetic will facilitate design and synthes

219 ated if TTT-28, a newly synthesized thiazole-valine peptidomimetic, could reverse ABCB1-mediated MDR

220 sential amino acids: tryptophan, isoleucine, valine, phenylalanine, leucine, threonine, lysine, histi

221 d seawater amended with tetrapeptide alanine-valine-phenylalanine-alanine (AVFA), a fragment of RuBis

222 e are a FCGR3A dimorphism resulting in CD16A-valine/phenylalanine-158 allotypes with different IgG af

223 ry minor role in the processing of all three valine polycistronic transcripts.

224 isease phenotype is modified by a methionine/valine polymorphism at codon 129 of the prion protein ge

225 ease duration, atrophy, codon 129 methionine valine polymorphism, Medical Research Council Rating Sca

226 valent of valine in the conserved Kv proline-valine-proline (PVP) motif, Cd(2+) forms intrasubunit co

227 his end, we analyzed the role of a conserved valine-proline (VP) motif in the C-terminal domain of CR

228 elated gene (hERG) channels lack the proline-valine-proline motif and the location of the intracellul

229 he inner S6 helices near a conserved proline-valine-proline motif, which introduces a kink that allow

230 the substrate-binding pocket of COP1 via two valine-proline peptide motifs, which represent a known i

231 core genes encoding glycerate kinase (glxK), valine-pyruvate transaminase (avtA), superoxide dismutas

232 The leucine- and valine-raising allele was not associated with AD (p = 0.

233 peaks as either from isoleucine, leucine, or valine reduces the search space by many orders of magnit

234 reover, mutagenesis analyses revealed that a valine residue at position 264 in the rat p75 neurotroph

235 Only mutation of the H-helix valine residue V228 to leucine prevented phosphorylation

236 sine and the transfer of a methyl group to l-valine residue.

237 ich negatively affect protease activity, and valine residues 785 and 787, which negatively affect deu

238 e residues arose from their replacement with valine residues and was not observed with other substitu

239 The leucine and valine residues insert into the binding groove while the

240 approximately 500 nM), by replacing the two valine residues with tert-leucine and the C-terminal pro

241 ic protein with an unusually high content of valine residues.

242 gauche(-) side-chain rotamer for one of the valine residues.

243 200, and 100 nM for isoleucine, leucine, and valine, respectively.

244 chemoirradiative procedure by showing that a valine-restricted diet is sufficient to empty the bone m

245 In mice fed a valine-restricted diet, HSC frequency fell dramatically

246 Furthermore, dietary valine restriction emptied the mouse bone marrow niche a

247 in HSC maintenance and suggest that dietary valine restriction may reduce iatrogenic complications i

248 ransmembrane anchor or an artificial leucine-valine sequence yielded normal fusion activities.

249 e fusion machinery, or by artificial leucine-valine sequences.

250 inositol, phosphocholine, sylloinositol, and valine showed statistically significant different concen

251 The smaller valine side chain in PR(I50V) eliminated hydrophobic int

252 molecule, whereas introduction of a bulkier valine side chain selectively blocked GTP binding by ste

253 ike polymerases, with leucine, isoleucine or valine steric gates, in many taxa of the phylum Actinoba

254 novel mutations including a glutamic acid to valine substitution (E1338D), a glutamine to leucine sub

255 strate that the single amino acid alanine to valine substitution at position 117 (A117V) in the NS2A

256 e APP gene that corresponds to an alanine to valine substitution at position 673 in APP (A673V), or p

257 om delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase).

258 sine-to-phenylalanine (Y-F) and threonine-to-valine (T-V) capsid mutants, designed to avoid proteasom

259 nd guanosine) and kokumi (gamma-l-glutamyl-l-valine) taste-related molecules was ascertained both in

260 d chain amino acids (isoleucine, leucine and valine) that have been identified previously as potentia

261 Alanine, valine, threonine (often in N-alpha-acetylated form), an

262 n of many amino acids, including isoleucine, valine, threonine, and 4-aminobutanoate, which has been

263 the second antibody, the side chain of HCDR3 valine ties into site I like IL-6R Phe(279), whereas a L

264 ild-type hMD-2, a relatively minor change of valine to alanine at position 135 completely abolished t

265 variant on the maternal allele results in a valine to alanine substitution at residue 163 (p.Val163A

266 PRNP sequencing demonstrated a valine to glycine mutation at codon 176, with valine hom

267 ution resulting in an amino acid change from valine to isoleucine at residue 19 of Nsp1beta diminishe

268 caused by a single substitution, a change of valine to methionine at position 429 (V429M), within the

269 The mutation resulted in a substitution of valine to methionine at residue 118 of the VEGF-D protei

270 beta3 subunits having gain-of-function V9'S (valine to serine at the 9'-position) mutations in transm

271 bic (in)activation and oxygen tolerance, the valine-to-histidine mutation has the most spectacular ef

272 Approximately 4% of black Americans carry a valine-to-isoleucine substitution (V122I) in the transth

273 rvival in the majority of U.S. subjects with valine-to-isoleucine substitution at position 122 (Val12

274 the effects of both valine-to-methionine and valine-to-leucine substitutions at this position in both

275 study, we characterized the effects of both valine-to-methionine and valine-to-leucine substitutions

276 In humans, a valine-to-methionine mutation (V144M) in ADAT3 that orig

277 ance, including recruitment of mitochondrial valine transfer RNA (tRNA(Val)) to play an integral stru

278 ired for the initial separation of all seven valine tRNAs from three distinct polycistronic transcrip

279 ase in the levels of both type I and type II valine tRNAs.

280 e circulating levels of isoleucine, leucine, valine, tyrosine, and phenylalanine, as well as single-n

281 A) signature, including isoleucine, leucine, valine, tyrosine, and phenylalanine, has been associated

282 and single mutation analysis revealed that a valine (V) residue at position 190 in HA is responsible

283 Specifically, we demonstrate that two valine (V) residues and beta-strand propensity in QVKEVT

284 polymerase at amino acid 150 (alanine [A] to valine [V]), V at position 150 was observed in 42% of pa

285 Isomeric amino acid residues such as valine (Val) and norvaline (Nva) are common in recombina

286 Subjects with the Methionine (Met)/Valine (Val) and Val/Val genotypes showed higher fractio

287 acids (BCAAs) leucine, isoleucine (Ile), and valine (Val) in the mitochondria efficiently allows the

288 in synthesis, to the proteinogenic, branched valine (Val) in their propensity to mistranslate isoleuc

289 des with leucine (LRP), phenylalanine (FRP), valine (VRP), and alanine (ARP) residues at these positi

290 physicochemically similar amino acids (e.g. valine vs. leucine), indicating that LCDs composed of re

291 is a chiral amide base synthesized from (S)-valine was determined by single-crystal X-ray diffractio

292 Cbz-protected (S)-valine was first coupled to the amino group of (S)-m-tri

293 arkably, the specificity against non-cognate valine was not improved by the presence of tRNA in eithe

294 PvfB modification of PvfC-tethered valine was observed directly by protein NMR spectroscopy

295 es from chlorination of lysine, tyrosine and valine were investigated.

296 d chain amino acids (leucine, isoleucine and valine) were also present in substantial amounts (5-8 mg

297 Amino acids such as phenylalanine and valine, which are not known to respond to cellular swell

298 with the exception of the branched chain AA valine, which was elevated in diabetic animals (P < 0.05

299 nts in the NCI-60 lung carcinoma cell lines, valine with high expression and isoleucine with low expr

300 oefficients were found for glutamic acid and valine, with regards to blood orange juice, and for phen