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1 459 in each group with BE or self-expanding valves).
2 driven changes in diameter upstream from the valve.
3 erwent attempted TPVR with a Sapien XT or S3 valve.
4 the blood pool, pulmonary veins, and mitral valve.
5 underwent TPVR with either a Sapien XT or S3 valve.
6 ients receiving a 29-mm (39%) or 26-mm (34%) valve.
7 elopment and maintenance of lymphatic vessel valves.
8 ses were performed in human tricuspid aortic valves.
9 sis, is upregulated in human calcific aortic valves.
10 aortic side of leaflets of explanted aortic valves.
11 advantages over other commercially available valves.
12 similar durability as surgical bioprosthetic valves.
13 was unrelated to AF and inserted mechanical valves.
14 ession of calcium volume score in the aortic valve (14% [95% CI, 5-24] versus 98% [95% CI, 77-123]; P
15 uals with Marfan syndrome or bicuspid aortic valve, a family history of AD was associated with an RR
18 ocedural characteristics were collected, and Valve Academic Research Consortium-2 outcomes were repor
21 Evolut R/PRO implantation in bicuspid aortic valve anatomy; a higher rate of moderate-severe paravalv
23 eplacement with the first generation Portico valve and delivery system or a commercially available va
24 core. EE more frequently involved the aortic valve and prosthesis (64.3% vs. 46.7%; p < 0.001; and 35
26 ences, EE more frequently affects prosthetic valves and less frequently pacemakers/defibrillators.
29 trial (The Placement of Aortic Transcatheter Valves) and registry the outcomes after aortic valve rep
30 ification of Rvol using valve tracking (Rvol(VALVE)), and semiautomated quantification of Rvol using
32 e of a highly reduced labiate process on its valve; and this evolutionary position is robustly suppor
34 SA) compared with any commercially available valves are needed to compare performance among designs.
35 (50.4% men; mean age, 77 years) with aortic valve area <1.3 cm(2) and analyzed the occurrence of all
37 out imaging demonstrated that smaller aortic valve area is predictive of increased risk for aortic va
39 onstructed a polygenic risk score for aortic valve area, which in a separate cohort of 311 728 indivi
41 causes a progressive narrowing of the aortic valve as a consequence of thickening and calcification o
42 conduit as the fixed effect of interest and valve as a fixed nuisance effect with post hoc pairwise
43 s of left-sided suspected IE (188 prosthetic valves/ascending aortic prosthesis and 115 native valves
44 ed survival free of surgery on the implanted valve at 10 years (Melody, 87%, versus SPVR, 87%; P=0.54
45 ve maladapts in those patients rendering the valve at least partially culpable for its dysfunction.
46 re frequent in transcatheter versus surgical valves at 30 days (13% vs. 5%; p = 0.03), but not at 1 y
47 performed by switching a couple of solenoid valves at branched outlets according to signals obtained
52 stribution, geologists have documented fault valving behavior, that is, cyclic changes in pressure an
54 coronary artery, thoracic aorta, and cardiac valve calcium scores and pulse wave velocity were not si
55 tcomes and hemodynamic performance may guide valve choice in this cohort of patients undergoing trans
56 ] men, median age 62 years, 153 [66%] native valves) comprised 58 (25%) PVC results and 173 (75%) neg
60 nt with Tetralogy of Fallot, a serious heart valve defect, affects the substrate selectivity of ADAM1
62 re replacement, catheter-based bioprosthetic valve deployment offers a minimally invasive treatment o
64 base-case analysis, patients with structural valve deterioration requiring reoperation were assumed t
67 Superconductor(S)/Ferromagnet(F) pseudo spin-valve devices based on amorphous [Formula: see text] thi
69 Database, we identified patients with aortic valve disease admitted 2012 to 2016 for SAVR, TAVR, and
70 links between the polygenic score for aortic valve disease and key health-related comorbidities invol
73 m patients aged over 70 years who had mitral valve disease or atrial fibrillation when compared with
75 HF (including ischemic heart disease, aortic valve disease, atrial fibrillation, congenital heart dis
76 o investigate the genetic etiology of aortic valve disease, perform clinical prediction, and uncover
77 , >=3 positive blood culture bottles, native valve disease, prosthetic valve, previous IE, and cardia
79 ailure, prior endocarditis, and degenerative valve disease; and had higher median age-adjusted Charls
80 -/-) mice, we tested our method on lymphatic valves displaying a wide range of dysfunction, from full
81 were varied to determine the impact of TAVR valve durability on life expectancy in a cohort of low-r
82 as conducted to determine the impact of TAVR valve durability on life expectancy in younger age group
85 eased in patients with more than mild aortic valve dysfunction but was independent from BAV leaflet f
86 int of view: When the shell is closed, the 2 valve edges meet each other in a commissure that forms a
87 dable Edwards-SAPIEN, SAPIEN XT, or SAPIEN 3 valve [Edwards LifeSciences, Irvine, CA, USA]; or a supr
88 delivery system or a commercially available valve (either an intra-annular balloon-expandable Edward
92 IE particularly in the setting of prosthetic valve endocarditis, paravalvular extension of infection,
93 e diagnosis of device-related and prosthetic valve endocarditis, that addition has not been incorpora
97 To gain mechanistic understanding of cardiac valve formation at single-cell resolution and insights i
101 for the quantitative assessment of lymphatic valve function utilizes the servo-null micropressure sys
103 At 30-day follow-up, median mean mitral valve gradient was 7 mm Hg, most patients (96.7%) had mi
104 e Portico valve group than in the commercial valve group (52 [13.8%] vs 35 [9.6%]; absolute differenc
105 ys, the event rate was higher in the Portico valve group than in the commercial valve group (52 [13.8
106 ortico group vs 48 [13.4%] in the commercial valve group; difference 1.5%, 95% CI -3.6 to 6.5 [UCB 5.
108 cond-generation SAPIEN XT balloon-expandable valve has a higher 5-year rate of SVD, whereas the third
109 replacement using aortic transcatheter heart valves has recently become an alternative for patients w
110 duced leaflet motion of bioprosthetic aortic valves have been documented by four-dimensional computed
112 ly lower for native valve IE than prosthetic valve IE and cardiac implantable electronic devices IE.
113 r, sensitivity was markedly lower for native valve IE than prosthetic valve IE and cardiac implantabl
114 II Trial: Placement of AoRTic TraNscathetER Valves II - High Risk and Nested Registry 7 [PII S3HR/NR
115 II Trial: Placement of AoRTic TraNscathetER Valves II - PARTNER II - PARTNERII - S3 Intermediate [PA
116 II Trial: Placement of AoRTic TraNscathetER Valves II - PARTNER II - PARTNERII - S3 Intermediate [PA
118 nificant paravalvular leak (P=0.004), second valve implantation (P=0.013), and valve embolization (P=
120 mboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an
123 sfusion Requirements in Transcatheter Aortic Valve Implantation (TRITAVI) registry retrospectively in
125 al characteristics were collected, including valve implantation depth and membranous septum length, a
127 llow-up after TAVI with a balloon-expandable valve in 3.5% of patients and was successful in all pati
128 intracardiac connections, with the tricuspid valve in the normal position and normal size of the left
129 , 40%, and 50% shorter than that of surgical valves in 40-, 50-, and 60-year-old patients, respective
134 d phenotypic changes occurring in the aortic valve interstitial cells (VICs) during osteogenic differ
136 n in future trials to determine if tricuspid valve intervention improves outcomes in this high-risk g
139 sed method, the competence of each lymphatic valve is challenged over a physiological range of pressu
140 ortic balloon-expandable transcatheter heart valves is associated with a low complication rate, a 30-
141 nd that the opening and closing of lymphatic valves leads to significant changes in axial strain thro
147 paradigm and hypothesize that the tricuspid valve maladapts in those patients rendering the valve at
150 ival with the originally implanted pulmonary valve (Melody group, 80%; SPVR group, 73%; P=0.46) betwe
152 large pediatric cohort of patients with BAV, valve morphology, AS, and AI are independently associate
153 , patients suffering from posterior urethral valves (n = 49), spina bifida (n = 21), central neurogen
155 cterial growth in cultures of resected heart valves of patients with infective endocarditis (IE) is i
160 II Trial: Placement of AoRTic TraNscathetER Valves - PII A [PARTNERII A]; NCT01314313; The PARTNER I
162 Advanced imaging planning, new transcatheter valve platforms, procedure streamlining and growing oper
167 10 between TAVR and SAVR until transcatheter valve prosthesis failure time was 70% shorter than that
170 tients with BPVT had a higher probability of valve re-replacement (68% vs. 24% at 10 years' post-BPVT
171 from 39 patients in sinus rhythm with mitral valve regurgitation (group 2; 32 males; 59+/-12 years).
172 ned for treatment of postoperative pulmonary valve regurgitation in patients with repaired right vent
174 icant serositis and severe mitral and aortic valve regurgitation, controlled with adalimumab, tacroli
176 of procedural secondary outcomes (eg, aortic valve reintervention, pacemaker rates) were more closely
177 ructural valve deterioration (SVD), based on valve related reintervention or death, underestimate the
179 tral regurgitation with transcatheter mitral valve repair (TMVr) using the MitraClip plus guideline-d
180 ealth status benefit of transcatheter mitral valve repair (TMVr) with MitraClip in patients with mitr
181 l Regurgitation) trial, transcatheter mitral valve repair (TMVr) with the MitraClip rapidly improved
185 ne-directed medical therapy, surgical mitral valve repair or replacement, and, in the setting of adva
187 bitors, vericiguat, and transcatheter mitral valve repair, all of which incrementally improve prognos
188 guiding the procedure (mitral and tricuspid valve repair, left atrial appendage closure, and paraval
189 ation; coronary artery bypass surgery; heart valve repair/replacement; percutaneous coronary interven
190 erior and may be superior to surgical aortic valve replacement (SAVR) for mortality, stroke, and reho
191 a reasonable alternative to surgical aortic valve replacement (SAVR) for patients with severe aortic
192 severe aortic stenosis after surgical aortic valve replacement (SAVR) or transcatheter aortic valve r
193 replacement (TAVR) and redo surgical aortic valve replacement (SAVR) represent the 2 treatments for
194 Valve-in-valve (VIV) transcatheter aortic valve replacement (TAVR) and redo surgical aortic valve
195 sist device (LVAD), and transcatheter aortic valve replacement (TAVR) are expensive cardiovascular te
199 ial results showed that transcatheter aortic valve replacement (TAVR) is noninferior and may be super
205 ding the indication for transcatheter aortic valve replacement (TAVR) to low-risk patients with sympt
215 dney injury early after transcatheter aortic valve replacement and is an independent predictor of 30-
216 ings may have implications for the timing of valve replacement and the role of adjunctive medical the
217 cation for transfemoral transcatheter aortic valve replacement as agreed by the heart team were rando
220 13, relative to baseline trends, the odds of valve replacement decreased by 4.0% per quarter (odds ra
221 their risk of reaching a clinical end point (valve replacement for symptoms, hospitalization, or card
222 ted patients undergoing transcatheter aortic valve replacement from November 1, 2011 to June 30, 2016
224 AVI trials (Surgical or Transcatheter Aortic Valve Replacement in Intermediate-Risk Patients) to 100%
225 ar atrial fibrillation; transcatheter aortic valve replacement in patients with symptomatic severe ao
227 In patients undergoing transcatheter aortic valve replacement in the US, vascular complications and
228 tic valve replacement versus surgical aortic valve replacement in the whole cohort and within each fl
232 ra-large aortic annuli, transcatheter aortic valve replacement using 29-mm Sapien-3 and 34-mm ER is s
234 clinical events between transcatheter aortic valve replacement versus surgical aortic valve replaceme
235 aortic annuli underwent transcatheter aortic valve replacement with 29-mm Sapien-3 (n=640) or 34-mm E
236 cular access method, to transcatheter aortic valve replacement with the first generation Portico valv
238 s with severe symptomatic AS awaiting aortic valve replacement, there has been a trend of increasing
239 ed of a total of 22 876 referrals for aortic valve replacement, with (N=8098) TAVR and (N=14 778) SAV
249 ents after transfemoral transcatheter aortic valve replacement; propensity score-matching identified
250 ntation (eg, transcatheter aortic and mitral valve replacements) was further elucidated in large-coho
253 gaps or overlaps despite the fact that each valve, secreted by 2 mantle lobes, may present antisymme
256 his ex vivo modeling system, clinically used valve-sparing aortic root replacement conduit configurat
257 graft configurations are clinically used for valve-sparing aortic root replacement, some specifically
259 04 [95% CI, 0.77-1.39]; P=0.810), and aortic valve stenosis (OR, 1.03 [95% CI, 0.56-1.90]; P=0.926).
260 subjects with a medical diagnosis of aortic valve stenosis (remaining n=308 683 individuals), phenom
261 ssociated with causal risk ratios for aortic valve stenosis and replacement, respectively, of 1.52 (9
264 t in patients with symptomatic severe aortic valve stenosis; and antiplatelet agents vorapaxar and pr
265 EDV) E/A ratio and 4D flow derived tricuspid valve stroke volume demonstrated independent association
267 2.18; 95% CI, 1.71-2.77) and mitral + aortic valve surgery (1.85; 95% CI, 1.33-2.58) and lowest after
268 e subset of patients who underwent tricuspid valve surgery (n = 344), a post-operative improvement in
269 oss procedure performed after initial aortic valve surgery achieves superior long-term survival and f
274 FLD-bioassay-RP-HPLC-UV/vis-ESI(-)-MS with a valve switch and NP-HPLC-UV/vis/FLD-bioassay-RP/IEX-HPLC
276 g intra-annular Portico transcatheter aortic valve system (Abbott Structural Heart, St Paul, MN, USA)
277 here, a programmable epidermal microfluidic valving system is devised, which is capable of biofluid
278 g of open circulatory systems, have flexible valving systems between thorax and abdomen that can sepa
280 include a torus-margo structure acting as a valve that prevents air from spreading between tracheids
282 For patients with severely impacted aortic valves that require replacement, catheter-based bioprost
283 se for many decades, but transcatheter heart valve therapy has revolutionized the field in the past 1
285 American College of Cardiology Transcatheter Valve Therapy Registry, we evaluated patients undergoing
287 rdial infarction, stroke, aortic dissection, valve thrombosis, endocarditis, and urgent cardiac inter
289 with self expanding (SE) transcatheter heart valves (THVs) on individual end points after transcathet
292 , semiautomated quantification of Rvol using valve tracking (Rvol(VALVE)), and semiautomated quantifi
293 derived MV regurgitation quantification than valve tracking in terms of agreement with indirect quant
295 UFA incorporation into human stenotic aortic valves was higher in noncalcified regions compared with
296 P/IEX-HPLC), UV/vis detector, and a Rheodyne valve were installed between the zone eluting interface
297 hort available, we observed that Sapien 3 BE valves were associated with lower rates of all-cause dea
299 tients required the implantation of a second valve, which led to an overall procedural success rate o