ライフサイエンスコーパス: valyl-tRNA synthetase

1 crimination were functionally independent in valyl-tRNA synthetase.

2 case of inner mitochondrial membrane 50, and valyl-tRNA synthetase.

3 in all known LeuRSs and also isoleucyl- and valyl-tRNA synthetases.

4 mportant for proper recognition of tRNAValby valyl-tRNA synthetase.19F NMR also shows that formation

5 Valyl-tRNA synthetase, a close homolog of isoleucyl-tRNA

6 tic analyses of beta-tubulin, chaperonin 60, valyl-tRNA synthetase, and EF-1alpha, suggests a sister-

7 Valyl-tRNA synthetase catalyzes aminoacylations of CoA-S

8 NMR also shows that formation of the tRNAVal-valyl-tRNA synthetase complex does not disrupt the first

9 Valyl-tRNA synthetase does not edit wild-type tRNA(Val)(

10 the homologous isoleucyl-tRNA synthetase and valyl-tRNA synthetase editing active sites, play a centr

11 in the 5' untranslated region of a putative valyl-tRNA synthetase gene, valRS.

12 the evolutionary-related IleRS, leucyl- and valyl-tRNA synthetases (I/L/VRSs), all efficiently hydro

13 tive peptide 1; CP1 domain), LeuRS resembles valyl-tRNA synthetase in its reliance on post-transfer e

14 pecificity nor interaction specifically with valyl-tRNA synthetase is crucial.

15 Valyl-tRNA synthetase is unable to hydrolytically deacyl

16 l-tRNA synthetase misactivates valine, while valyl-tRNA synthetase misactivates threonine.

17 es, are abolished in a temperature-sensitive valyl-tRNA synthetase mutant (un-3(ts)) that has high le

18 Valyl-tRNA synthetase specifically protects the anticodo

19 hing the identity of the human mitochondrial valyl-tRNA synthetase then inducing its overexpression i

20 or analyses of isoleucyl-tRNA synthetase and valyl-tRNA synthetase, these experiments provide the bas

21 ransient overexpression of editing-defective valyl-tRNA synthetase (ValRS(ED)) activated DNA break-re

22 actions between Escherichia coli tRNAVal and valyl-tRNA synthetase (ValRS) by enzymatic footprinting

23 mologs isoleucyl-tRNA synthetase (IleRS) and valyl-tRNA synthetase (ValRS) deacylate Val-tRNA(Ile) an

24 Valyl-tRNA synthetase (ValRS) has difficulty differentia

25 Valyl-tRNA synthetase (ValRS) has difficulty discriminat

26 uRS), isoleucyl-tRNA synthetase (IleRS), and valyl-tRNA synthetase (ValRS) have evolved a discrete ed

27 uRS), isoleucyl-tRNA synthetase (IleRS), and valyl-tRNA synthetase (ValRS) share a common insertion,

28 n Escherichia coli tRNAValfor recognition by valyl-tRNA synthetase (ValRS), nucleotides in the accept

29 g that diminish the proofreading activity of valyl-tRNA synthetase (ValRS).

30 For isoleucyl- (IleRS) and valyl-tRNA synthetases (ValRS), reactions that hydrolyze

31 d thereby identified a segment of the enzyme valyl-tRNA-synthetase (ValRS).

32 wo previously reported biallelic variants in valyl-tRNA synthetase (VARS) in ten patients with a deve