ライフサイエンスコーパス: vascular bed

1 urces during embryogenesis, depending on the vascular bed.

2 pression can result in a more stable retinal vascular bed.

3 ace area in tight apposition to an extensive vascular bed.

4 ved blood flow patterns throughout the islet vascular bed.

5 nts, but efficacy may depend on the involved vascular bed.

6 yx in angiogenic sprouting in the developing vascular bed.

7 dependent on the resistance of the pulmonary vascular bed.

8 s but not survival of mature vessels in this vascular bed.

9 mal selectivity and efficacy in the intended vascular bed.

10 elopment and is strictly associated with the vascular bed.

11 embrane potential within the skeletal muscle vascular bed.

12 frames as the heart pushes blood through the vascular bed.

13 changes in various portions of the pulmonary vascular bed.

14 uring acute hypoxemia, such as the umbilical vascular bed.

15 ed vasodilatation and desensitization in the vascular bed.

16 trk B by capillaries and arterioles in this vascular bed.

17 accumulate particularly within the placental vascular bed.

18 th observed alterations in the primary tumor vascular bed.

19 vitro when perfused through their intrinsic vascular bed.

20 n, with potentially different potency across vascular beds.

21 VSMC in a spatiotemporal fashion across all vascular beds.

22 small resistance arteries in the splanchnic vascular beds.

23 and vascular endothelial function in several vascular beds.

24 gand-receptors common or specific to certain vascular beds.

25 as drastically different effects on distinct vascular beds.

26 ompetition between respiratory and locomotor vascular beds.

27 thelial expression of ANTXR2/CMG2 in several vascular beds.

28 this mechanism may not equally apply to all vascular beds.

29 tly reduced promoter activity in a subset of vascular beds.

30 ulted in increased LacZ staining in multiple vascular beds.

31 markable target tissue tropisms for selected vascular beds.

32 into new clinical treatments across multiple vascular beds.

33 nse response, with marked differences across vascular beds.

34 cted to compare risk factor relations across vascular beds.

35 gulates vascular tone in multiple peripheral vascular beds.

36 nnuli is related to atherosclerosis in other vascular beds.

37 marked differences in lectin binding between vascular beds.

38 ly extends vessel length in these developing vascular beds.

39 es, but differences are evident in different vascular beds.

40 c acid (20-HETE) in blood vessels of several vascular beds.

41 or actions in fetal essential and peripheral vascular beds.

42 ctural and functional abnormalities of other vascular beds.

43 primary human EC from different tissues and vascular beds.

44 tensively and colonized the appropriate host vascular beds.

45 le of proteins in several well-characterized vascular beds.

46 dhesion molecules expressed within different vascular beds.

47 ntial recruitment of leukocytes at different vascular beds.

48 planes in arteries explanted from different vascular beds.

49 an arteries and veins of different sizes and vascular beds.

50 ging physiological conditions within diverse vascular beds.

51 constricts with hypoxia in contrast to other vascular beds.

52 hemostatic regulatory pathways in individual vascular beds.

53 what leads to fibrin formation in different vascular beds.

54 al cells (ECs) are highly specialized across vascular beds.

55 for developing distinct arterial and venous vascular beds.

56 inking on active vasodilatation in these two vascular beds.

57 GE2 regulates regional blood flow in various vascular beds.

58 in the degradation of bradykinin in several vascular beds.

59 , expression of vWF varies between different vascular beds.

60 s, including coronary, mesenteric, and renal vascular beds.

61 rences in response to these hormones between vascular beds.

62 othelial channels in the endothelia of these vascular beds.

63 EPCR expression varies dramatically among vascular beds.

64 nctional characteristics of ECs in different vascular beds.

65 t not the coronary, abdominal, or peripheral vascular beds.

66 elated to the presence of aneurysms in other vascular beds.

67 gnaling in the development of organ-specific vascular beds.

68 isms and therapeutic targeting of individual vascular beds.

69 tablishment of late-forming, tissue-specific vascular beds.

70 thromboembolic occlusions affecting diverse vascular beds.

71 wn maturation factors act universally in all vascular beds.

72 and neovascularization but spared quiescent vascular beds.

73 ctors in splanchnic, hepatic, and collateral vascular beds.

74 l-ankle PWV), and mixed (brachial-ankle PWV) vascular beds.

75 heterogeneity of F8 expression in different vascular beds.

76 p of angiogenic sprouts in several mammalian vascular beds.

77 relative values of resistances in different vascular beds.

78 fied in the extracted lipid portion from all vascular beds.

79 and reduced deposition in deep postcapillary vascular beds.

80 man endothelial cells derived from different vascular beds.

81 ry, cerebral, splanchnic and skeletal muscle vascular beds.

82 involvement of cephalocervical and/or renal vascular beds (32% in males versus 80% in females).

83 culature of adjacent, nonischemic mesenteric vascular beds, a phenomenon well established in other or

84 In many vascular beds, adhesive interactions between leukocytes

85 otch1DeltaEC/Notch4(-/-)) had defects in all vascular beds affected in Adam10DeltaEC mice.

86 ding patients with polyvascular disease (>=2 vascular beds affected with atherosclerosis), impaired r

87 ation can identify higher-risk patients (>=2 vascular beds affected, HF, renal insufficiency, or diab

88 ng the REACH score were those with 2 or more vascular beds affected, history of heart failure (HF), o

89 cy, and by CART analysis were those with >=2 vascular beds affected, history of HF, or diabetes.

90 ve as an important mechanism that protects a vascular bed against the damaging effects of nitrogen mo

91 were correlated with quantity of CAP in all vascular beds (all p<0.05); no differences in the streng

92 on varies depending upon the anatomical site/vascular bed analyzed.

93 ccording to the anatomical sites and diverse vascular beds analyzed.

94 rteries extending the depth of the placental vascular bed and accelerating vessel remodeling.

95 at statins have benefits beyond the coronary vascular bed and are capable of reducing ischemic stroke

96 mp2 gene in odontoblasts on formation of the vascular bed and associated pericytes in the pulp.

97 sive neointimal lesions across the pulmonary vascular bed and does so in a stereotyped timeframe.

98 f the native portal inflow despite a reduced vascular bed and dramatically elevated blood flow may re

99 hogenic role of thrombosis in the peripheral vascular bed and providing genetic support for Factor Xa

100 Blood flow was homogeneous through the vascular bed and replicated native flow patterns.

101 onsiderable thickening of both the choroidal vascular bed and scleral coat, which provide nutritive a

102 CTGF is expressed in vascular beds and acts on multiple cell types.

103 calcium due to atherosclerosis in 5 distinct vascular beds and calcium in the aortic and mitral annul

104 onductance K(+) (IK and SK) channels in some vascular beds and endothelial nitric oxide synthase (eNO

105 he trafficking signals displayed by distinct vascular beds and epithelial cell layers in response to

106 a mosaic pattern in the capillaries of many vascular beds and in the aorta.

107 tial response of endothelial cells in distal vascular beds and large central blood vessels is establi

108 imary endothelial cells derived from various vascular beds and mouse retinal explants.

109 the maintenance of distinct arterial-venous vascular beds and that attenuation of the Alk1 signaling

110 d by endothelial cell activation in multiple vascular beds and the appearance of activated immune cel

111 to apoptosis and subsequent growth at target vascular beds and tissues in distant organs.

112 bute the cardiac output away from peripheral vascular beds and towards essential circulations, such a

113 n alpha(1)AR subtype expression differs with vascular bed, and (2) age influences human vascular alph

114 s have a significant impact on the heart and vascular bed, and descriptions of echocardiographic find

115 lve a direct peptide effect on the choroidal vascular bed, and the AII-mediated potentiation of sympa

116 transduce signaling events, in particular in vascular beds, and how endothelial cell integrins can be

117 de maintains differentiated smooth muscle in vascular beds, and its synthetic enzyme cystathionine-ga

118 Formation and remodeling of vascular beds are complex processes orchestrated by mult

119 ery of oxygen and nutrients, but independent vascular beds are highly specialized to meet the individ

120 thod in which peptides that home to specific vascular beds are identified after administration of a p

121 vasodilatation of the uterine and placental vascular beds are important at all stages of pregnancy,

122 ditional high-resolution studies in multiple vascular beds are required to address the therapeutic po

123 ss we develop new hypotheses about why these vascular beds are susceptible to sequestration of parasi

124 nesis by using the readily visualized ocular vascular bed as a surrogate to test pro- and antiangioge

125 parenchyma of the brain, leptomeninges, and vascular beds, as well as through secretion of biologica

126 ed in the sublingual, intestinal, and muscle vascular beds at the different time points and included

127 Adjustment for calcification in other vascular beds attenuated this association (HR: 1.40 [95%

128 tients are unable to vasoconstrict locomotor vascular beds beyond NB when presented with a respirator

129 for VEGF not only in the formation of ocular vascular beds but also in the differentiation of the len

130 We observed an association in the carotid vascular beds but not the coronary, abdominal, or periph

131 Tbdn-1 is not detected in most adult vascular beds but persists at high levels in the adult o

132 sities in gastrointestinal, uterine and skin vascular beds, but had mild effects in the brain.

133 differentially expressed in tissue-specific vascular beds, but its expression is induced in hematopo

134 se (SK) pathway is an important regulator of vascular beds, but its role in the survival and function

135 ration of infected erythrocytes (IE) in deep vascular beds, but the endothelial receptors involved in

136 ced vessel diameter and normalization of the vascular bed by coverage of mature pericytes and immunor

137 Impaired blood flow in the tumor vascular bed caused by structurally and functionally abn

138 rdigitated with quail vascular cells in most vascular beds colonized by graft cells.

139 9 loci were associated with disease in three vascular beds (coronary, cerebral, peripheral), includin

140 er vessels leading to circumscribed terminal vascular beds could account structurally for "lacunar" i

141 Event rates including all vascular beds declined from 0.61 to 0.16 (P<0.0001).

142 that CGRP-stimulated vasodilation in several vascular beds depends, at least in part, on nitric oxide

143 ation of perivascular cells selectively in a vascular bed destined to regress.

144 atherosclerotic stimuli might contribute to vascular bed differences in susceptibility to atheroscle

145 adenosine affects both systemic and coronary vascular beds differentially.

146 al determinant of vasorelaxation in numerous vascular beds, drugs influencing H(2)S biosynthesis offe

147 osis serves to open capillary lumens in this vascular bed during glomerular development.

148 0 different primary human ECs from different vascular beds during the early stages of hypoxia.

149 l cell networks into patterns reminiscent of vascular beds, even on plastic and glass.

150 venous circulation of an arterially occluded vascular bed evokes sympathetic activation in healthy in

151 Of the five vascular beds examined, atherosclerosis was present in o

152 ursor that gives rise to VSMC in vivo in all vascular beds examined.

153 ock does not impair blood flow to any of the vascular beds examined.

154 the Flt-1 promoter directs expression in all vascular beds except for the liver.

155 Limb vascular beds exhibit a graded dilatation in response to

156 r coagulopathy, endothelial dysfunction, and vascular bed failure.

157 elivery, and suggest that one can create new vascular beds for a variety of applications with this ma

158 ng-(1-7) was measured in perfused mesenteric vascular beds from rats after bile-duct ligation.

159 ion of vascular endothelial growth factor to vascular beds generated immediate and robust vascular tr

160 ngiogenesis and maintaining the newly formed vascular beds has become a major goal of tissue engineer

161 ythmic leukocyte adhesion plays in different vascular beds has not been studied.

162 is effect of exercise primarily manifests in vascular beds highly perfused during exercise, it has be

163 n the absence of a preexisting or developing vascular bed, i.e., in the absence of angiogenesis, in t

164 lation in patients with a reactive pulmonary vascular bed in a selective, safe and expeditious fashio

165 tical component in the reorganization of the vascular bed in response to angiogenic stimuli.

166 ombosis or pregnancy loss), depending on the vascular bed in which this interaction occurs.

167 The model should deal with vascular beds in all tissues, and the computational infr

168 expression triggers the formation of ectopic vascular beds in embryos.

169 n to be a major component of EDHF in several vascular beds in multiple species, including in humans.

170 nd efficiently retargeted gene expression to vascular beds in other organs.IMPORTANCE In the aggregat

171 , irregular plaques should occur in multiple vascular beds in some individuals more frequently than w

172 the mechanisms driving the expansion of new vascular beds in the adult needs further investigation.

173 ns had exited the blood stream and docked at vascular beds in the brain, the application of an extern

174 odilator actions in essential and peripheral vascular beds in the fetus in late gestation.

175 OX-1 pathway in the pulmonary and peripheral vascular beds in the rat and that TXA2 is a major prosta

176 ree to four beds in 11 (8%), and in all five vascular beds in two (1%).

177 on factor in cells removed from a functional vascular bed; in this regard there is evidence indicatin

178 organ-specific phenotypes in representative vascular beds including arteries and veins, heart, lung,

179 brain; similar processes can occur in other vascular beds, including the lung.

180 hat regardless of developmental stage of the vascular bed, increased expression of VEGF in the retina

181 venous circulation of an arterially occluded vascular bed induces sympathetic activation and an incre

182 of white blood cells (WBCs) in the pulmonary vascular bed is crucial for an effective immune response

183 ce (CVC) during whole-body heat stress, this vascular bed is important in the regulation of blood pre

184 ll arterioles and the functional size of the vascular bed is increased.

185 tivity also influences the patterning of the vascular bed is not known.

186 reserve blood flow capacity of the coronary vascular bed is preserved.

187 wever, thrombotic occlusion of the placental vascular bed is rarely observed and the mechanistic rele

188 ternal and fetal systems, development of its vascular beds is essential to normal placental function,

189 Although analysis of changes in vascular beds is helpful for developing strategies for c

190 esenteric arteries, but involvement in other vascular beds is unclear.

191 rterial administration of EGCG to mesenteric vascular beds isolated ex vivo from WKY rats caused dose

192 Because 15-HETE is a constrictor in this vascular bed, it may play an important role in hypoxia-i

193 rin-B2 expression patterns vary in different vascular beds, it can extend into capillaries about midw

194 pinephrine induces vasoconstriction in other vascular beds, it may decrease visceral blood flow, impa

195 The hepatic sinusoid is a unique vascular bed lined by hepatic sinusoidal endothelial cel

196 Upon encountering the relevant vascular bed, lymphocytes attach to endothelial adhesion

197 hesis that full recruitment of the pulmonary vascular bed may decrease evidence of lung injury by rec

198 nduced NO-dependent effects in the umbilical vascular bed may provide an important mechanism in the c

199 ascribed to its ability to sequester in deep vascular beds, mediated by the variant surface antigen f

200 ries in skeletal muscle, and is unlike other vascular beds (mesentery).

201 ed apoptosis of endothelial cells within the vascular bed of a tumor, we show that a chemotherapeutic

202 We analyzed MAIT cells resident in the vascular bed of livers and showed that they represented

203 improved endothelial function in the forearm vascular bed of patients with type 1 diabetes and smoker

204 potent vasopressor activity in the pulmonary vascular bed of the cat and that this response may be me

205 e conditions in the isolated left lower lobe vascular bed of the cat, N omega-I-nitro-L-arginine meth

206 nephrine and other agonists in the pulmonary vascular bed of the cat.

207 ficant vasodilator activity in the pulmonary vascular bed of the cat.

208 blocker, were investigated in the pulmonary vascular bed of the cat.

209 AngII were investigated in the hindquarters vascular bed of the cat.

210 re "spare" AT1 receptors in the hindquarters vascular bed of the cat.

211 ion is proximal and distal within the muscle vascular bed of the human thigh.

212 pressing cells docked exclusively within the vascular bed of the ipsilateral carotid artery and that

213 In the feline pulmonary vascular bed of the isolated left lower lobe, norepineph

214 ve apoptosis of endothelial cells within the vascular bed of tumors.

215 llel mechanisms regulate angiogenesis in the vascular beds of both the heart and bone marrow.

216 ith impaired functional sympatholysis in the vascular beds of contracting forearm muscle in healthy m

217 mpathetic vasoconstriction is blunted in the vascular beds of contracting skeletal muscles.

218 e endothelial and smooth muscle cells in the vascular beds of skeletal muscle.

219 s, allowing parasites to sequester into deep vascular beds of various organs.

220 In the vascular beds of vertebrate animals blood flow is regula

221 of the environmental influence of different vascular beds on the in vivo endothelial responses to an

222 rct volumes, in the distribution of affected vascular beds or in the clinical severity of strokes.

223 g the value of radiologic screening of other vascular beds, particularly in asymptomatic males, in pa

224 nimal models and in human disease in various vascular beds, particularly the carotid arteries, is pre

225 rectly quantify atherosclerosis in different vascular beds performed in a single cohort.

226 Blood flow to vascular beds perfused by this artery does not seem to b

227 cal mechanisms controlling blood flow in the vascular beds perfused by this artery.

228 echanism of vascular repair may differ among vascular beds, pointing to the importance of coronary ar

229 Vascular bed preservation fluid was collected from 48 ki

230 control cellular functions-including in the vascular bed-primarily via regulation of lysosomal bioge

231 , GPR124 overexpression throughout all adult vascular beds produced CNS-specific hyperproliferative v

232 Arsenic exposure affects multiple vascular beds, promoting liver sinusoidal capillarizatio

233 The correlation in CAP scores across vascular beds ranged from 0.59 to 0.72.

234 ovessels of different types and in different vascular beds regulate the passage of small and large mo

235 g1 acts to maintain the endothelium in other vascular beds, regulating some actions of VEGF, these ob

236 signaling as a pathway controlling choroidal vascular bed relaxation and provide a pathogenic link wi

237 ee the reproducible anatomy of stereotypical vascular beds remains unclear.

238 to pump blood to the pulmonary and systemic vascular beds, respectively.

239 ses of haemodynamic changes in the umbilical vascular bed reveal an initial decrease in umbilical vas

240 cific T-cell interactions in the cremasteric vascular bed revealed that cognate recognition of the en

241 indicate that vasodilatation occurs in other vascular bed(s) to account for the lack of increase in a

242 ul model system, because it contains several vascular beds sandwiched between avascular tissue.

243 llution with markers of atherosclerosis in 4 vascular beds simultaneously in an all-African-American

244 Our study identifies an endogenous, vascular bed-specific anticoagulant pathway in microvasc

245 tion of the skin or lung, thereby uncovering vascular bed-specific differences in the prevention of i

246 information for environmentally responsive, vascular bed-specific expression in the heart, skeletal

247 indicate that distinct DNA modules regulate vascular bed-specific expression of VWF.

248 us targeting is a valuable tool for studying vascular bed-specific gene regulation, (2) the VWF and F

249 he local endothelial components that dictate vascular bed-specific hemostatic regulation.

250 AT1R-Abs acted in a vascular bed-specific manner and caused small contractio

251 to the liver and other organs is directed by vascular bed-specific mechanisms, including blood flow-r

252 use and human vWF promoters are regulated by vascular bed-specific mechanisms.

253 cal and systemic elements that contribute to vascular bed-specific prothrombotic potential.

254 ion and in vitro expansion, as well as rapid vascular bed-specific shifts in EC gene expression profi

255 neity and to use this information to develop vascular bed-specific therapies.

256 Vascular bed-specific TLR fingerprints were functionally

257 The architecture of an organ's vascular bed subserves its physiological function and me

258 blood flow elevations among and within those vascular beds subserving the contracting muscle(s).

259 BACKGROUND-Peripheral cutaneous vascular beds, such as the fingertips, contain a high co

260 om peripheral circulations towards essential vascular beds, such as the umbilical, cerebral, myocardi

261 justment for vascular calcification in other vascular beds, suggesting partial confounding by systemi

262 that resembled wild-type and colonized host vascular beds, suggesting that host-derived signals can

263 The vascular beds supplying the retina may sustain injury as

264 factors have a greater impact on CAP in one vascular bed than another.

265 te to pathologic alterations in nonplacental vascular beds that are associated with fibrinolysis.

266 a the HIF transcription factors in one large vascular bed, that underlying the skin, influences cardi

267 In contrast to any other vascular bed, the coronary circulation receives its perf

268 In contrast, in the umbilical vascular bed, the dilator response was not only prevente

269 stic expansion within a large Ccm1-deficient vascular bed, the lateral dorsal aorta.

270 ffuseness of TV involvement in the allograft vascular bed, the only currently definitive therapy requ

271 In marked contrast to other essential vascular beds, the mechanisms mediating maintained perfu

272 erosclerotic lesion size was quantified in 2 vascular beds: the ascending aorta and the aortic arch.

273 sodilates and O2 vasoconstricts the cerebral vascular bed; the opposite is true in the lungs.

274 that as the extent of CAA progressed in this vascular bed, there was increased prevalence of propagat

275 n hemostasis may be associated with distinct vascular beds, thus implying that the relative combined

276 episodes of ischemia with reperfusion in one vascular bed, tissue, or organ confer a global protectiv

277 The nature of this imbalance varies from one vascular bed to the next according to the local set poin

278 loss of an angiogenesis inhibitor, can prime vascular beds to be more responsive to an angiogenic sti

279 or determining the heterogeneous response of vascular beds to NO and NO-based vasodilators, thereby p

280 s of organization extending over scales from vascular beds to single cells, subcellular structures, a

281 arameter circulatory model with two parallel vascular beds; two distinct control mechanisms for both

282 ene expression programs across heterogeneous vascular beds under both physiologic and pathologic cond

283 circulating leukocytes in the rat peritoneal vascular bed using intravital microscopy.

284 y, acetylcholine, a powerful dilator of most vascular beds, virtually lost the ability to dilate cere

285 pressure-flow relationship in the pulmonary vascular bed was shifted to the right in animals transfe

286 ake of leptin by the splanchnic or pulmonary vascular beds was detected; leg tissue was a net leptin

287 Subsequent angiographic imaging of other vascular beds was negative.

288 e of changes over time between the different vascular beds was similar in both models, but the endoto

289 vessels distal to the coarctation, yet both vascular beds were exposed to the same circulating facto

290 Vascular beds were imaged selectively based on clinical

291 In vitro-perfused SMA vascular beds were tested for the cumulative dose-respon

292 found to be expressed in VSMCs from several vascular beds where they contribute to the regulation of

293 lates basal blood flow in the human coronary vascular bed, whereas substance P-stimulated vasodilatat

294 tment for the extent of calcium in the other vascular beds, whereas the thoracic aorta was significan

295 or vasculature, Ang-2 destabilizes the tumor vascular bed while improving perfusion in surviving tumo

296 ed pattern of arterial branching in multiple vascular beds while the venous system remained normal.

297 er birth, and to remodel the fetal pulmonary vascular bed whose outlet is obstructed.

298 veness to vasoconstrictors in the splanchnic vascular bed, with several vasoactive molecules, control

299 venular distension and to recruitment of the vascular bed within the skeletal muscles.

300 x data, measured across the human splanchnic vascular bed, within a genome-scale model of human metab