ライフサイエンスコーパス: vascular disorder

1 important manifestation of this multisystem vascular disorder.

2 nteric artery aneurysm (SMAA) is an uncommon vascular disorder.

3 ry Hemorrhagic Telangectasia, a rare genetic vascular disorder.

4 elangiectasia type 2 (HHT2), a multisystemic vascular disorder.

5 logical candidate for predisposition to this vascular disorder.

6 such as neurofibromas and may associate with vascular disorder.

7 potential therapeutic target for age-related vascular disorders.

8 wth of VSMC and may thus contribute to human vascular disorders.

9 ading to their increasing use for thrombotic vascular disorders.

10 both rare single-gene and common multigenic vascular disorders.

11 role in the pathogenesis of inflammatory and vascular disorders.

12 VSMC) and has been implicated in a number of vascular disorders.

13 jury plays a key role in the pathogenesis of vascular disorders.

14 ampering the development of gene therapy for vascular disorders.

15 n understanding the molecular basis of these vascular disorders.

16 an important insight into the mechanisms of vascular disorders.

17 ic strategies targeting LINC complex-related vascular disorders.

18 Cirrhosis is associated with hemodynamic and vascular disorders.

19 ictive potential in patients with underlying vascular disorders.

20 re prevalent in Nervous System disorders and Vascular disorders.

21 utic targets for the treatment of angiogenic vascular disorders.

22 steoporosis suggests a link between bone and vascular disorders.

23 othelial dysfunction, which is a hallmark of vascular disorders.

24 t of both normal immune response and various vascular disorders.

25 nt of many life-threatening and debilitating vascular disorders.

26 nd has been linked to various autoimmune and vascular disorders.

27 , little is known about division fidelity in vascular disorders.

28 tify S1PR2 as a novel therapeutic target for vascular disorders.

29 e metabolism that alleviate stroke and other vascular disorders.

30 ontribution to better evaluate these retinal vascular disorders.

31 ified several signaling pathways relevant to vascular disorders.

32 nephritis, chronic lung disease, sepsis, and vascular disorders.

33 hyperplasia and possibly other hyperplastic vascular disorders.

34 r age-related macular degeneration and other vascular disorders.

35 ow for potential new therapeutic targets for vascular disorders.

36 mmatory marker, are associated with systemic vascular disorders.

37 rdiovascular diseases, including obstructive vascular disorders.

38 ense mechanisms, atherosclerosis and related vascular disorders.

39 nse mechanisms, atherosclerosis, and related vascular disorders.

40 luding mental retardation and retinitis, and vascular disorders.

41 HIV (7% vs. 1.4%, p = .024), and peripheral vascular disorders (19% vs. 8%, p = .018).

42 -A3 group and 19 [3%] in the placebo group), vascular disorders (30 [2%] vs 17 [3%]), and neoplasm (b

43 (41%), cardiac arrhythmias (40%), peripheral vascular disorders (39%), alcohol abuse (36%), valvular

44 e pathogenesis of atherothrombosis and other vascular disorders accompanied by endothelial dysfunctio

45 ional vascular biology and toward a range of vascular disorders and approaches in tissue regeneration

46 S) enzyme are characterized by a plethora of vascular disorders and hyperhomocysteinemia.

47 rdiovascular diseases, including obstructive vascular disorders and hypertension.

48 a promising therapeutic target for treating vascular disorders and inflammatory conditions like seps

49 romboinflammatory activities in a variety of vascular disorders and vasculopathies.

50 deoxyribonucleotide with activity in several vascular disorders and, unlike t-PA and heparin, produce

51 hose with PAMM + RVD (n = 12) one (9%) had a vascular disorder, and four (44.4%) oral contraceptive u

52 angiectasia 2 (HHT2), a dominantly inherited vascular disorder, and pulmonary hypertension.

53 coagulation, systemic hypotension, ischemic vascular disorders, and autoimmune diseases.

54 tion, pigment epithelial detachment, retinal vascular disorders, and choroidal diseases and tumors.

55 y in treating human hypertension, peripheral vascular disorders, and coronary artery disease.

56 ding cardiomyopathies, arrhythmic disorders, vascular disorders, and lipid disorders such as familial

57 an important contributing factor in multiple vascular disorders, and vascular lesion severity is temp

58 ontrast, the data supporting AD as a primary vascular disorder are more convincing.

59 However, the pathogeneses of the more common vascular disorders are not well characterized.

60 The long-term consequences of ART-associated vascular disorders are unknown and difficult to investig

61 ly debilitating and life-threatening genetic vascular disorder arising from endothelial cell (EC) pro

62 topia, a disorder that leads to epilepsy and vascular disorders, as well as embryonic lethality.

63 clusion (RVO) is a sight-threatening retinal vascular disorder associated with macular edema and neov

64 new approaches to the future therapeutics of vascular disorders associated with diabetes.

65 ologic relevance of O-GlcNAc modification in vascular disorders associated with diabetes.

66 resent a novel therapeutic strategy to treat vascular disorders by improving endothelial dysfunction

67 ular lesions in the human autosomal dominant vascular disorder capillary malformation-arteriovenous m

68 nly reported adverse events were infections, vascular disorders, cardiac disorders, and neoplasms.

69 agic telangiectasia is an autosomal dominant vascular disorder caused by heterozygous, loss-of-functi

70 T) is a potentially life-threatening genetic vascular disorder caused by loss-of-function mutations i

71 syndrome is a rare autosomal recessive brain vascular disorder caused by mutation in FLVCR2 in humans

72 nfarcts and leukoencephalopathy (CADASIL), a vascular disorder caused by NOTCH3 mutations.

73 rrier function and to the development of the vascular disorder Cerebral Cavernous Malformation (CCM).

74 onsible for the development of the inherited vascular disorder cerebral cavernous malformations (CCM1

75 y hemorrhagic telangiectasia is an inherited vascular disorder characterized by arteriovenous malform

76 Generalized lymphatic anomaly (GLA) is a vascular disorder characterized by diffuse or multifocal

77 elangiectasia (HHT) is an autosomal dominant vascular disorder characterized by epistaxis, mucocutane

78 editary hemorrhagic telangiectasia type 1, a vascular disorder characterized by multisystemic vascula

79 heterogeneous group of sporadic or inherited vascular disorders characterized by localized lesions of

80 therosclerosis is a progressive inflammatory vascular disorder, complicated by plaque rupture and sub

81 tified PHACTR1 as key locus for five diverse vascular disorders: coronary artery disease, migraine, f

82 al calcification (MAC) is a chronic systemic vascular disorder distinct from atherosclerosis that is

83 Four deaths occurred on treatment due to vascular disorder (docetaxel plus capecitabine followed

84 Patients with known vascular disorders (eg, diabetes mellitus, coronary hear

85 mulin (Glmn), a protein found mutated in the vascular disorder glomuvenous malformation (GVM), binds

86 Two distinct pulmonary vascular disorders, hepatopulmonary syndrome (HPS) and p

87 Mutations in ENG lead to the inherited vascular disorder hereditary hemorrhagic telangiectasia

88 mily type I receptor implicated in the human vascular disorder hereditary hemorrhagic telangiectasia

89 Records of cervical vascular disorders (ie, aneurysm, cerebral infarction, t

90 Retinal vein occlusion is a common retinal vascular disorder in the elderly population of Nepal.

91 ial clinical evidence for the development of vascular disorders in human immunodeficiency virus (HIV)

92 Sortilin has been positively correlated with vascular disorders in humans.

93 ivity of the smMLCK, perhaps contributing to vascular disorders in hypertension.

94 higher than expected prevalence of systemic vascular disorders in individuals with glaucoma has been

95 the presence of either organic or functional vascular disorders in these individuals.

96 s, W could also provide early information on vascular disorders in those clinical situations.

97 are established risk factors in a variety of vascular disorders including coronary artery disease and

98 promised in several retinal degenerative and vascular disorders, including diabetic macular edema (DM

99 ial function of this transcription factor in vascular disorders, including hypertension and atheroscl

100 c strategies in the treatment of a number of vascular disorders, including hypertension, atherosclero

101 d autoimmune diseases, as well as cancer and vascular disorders, including thrombosis.

102 ity are key events in the pathophysiology of vascular disorders induced by hypoxia.

103 nction and have fundamental implications for vascular disorders involving dysregulated eNOS.

104 This vascular disorder is responsible for 1-2% of all deaths

105 angiectasia (HHT), the most common inherited vascular disorder, is caused by mutations in genes invol

106 erlie the majority of inherited cases of the vascular disorder known as pulmonary arterial hypertensi

107 l hypertension (PAH) is a hyperproliferative vascular disorder observed predominantly in women.

108 epatopulmonary syndrome (HPS) is a pulmonary vascular disorder occurring as a consequence of advanced

109 Placental malperfusion (PMP), a vascular disorder of impaired maternal or fetal placenta

110 Hypertension is a common multifactorial vascular disorder of largely unknown cause.

111 mortality in early life, evidence indicates vascular disorders of pregnancy and infantile pulmonary

112 ltitudes increases the incidence of maternal vascular disorders of pregnancy characterized by placent

113 o effective therapies exist to prevent these vascular disorders of pregnancy.

114 offers potential to improve visualization of vascular disorders of the eye.

115 Sympathetic nerves may play a role in vascular disorders of the eye.

116 viously included by the European Network for Vascular Disorders of the Liver, a multicenter prospecti

117 Arterioportal fistulas (APFs) are rare vascular disorders of the mesenteric circulation.

118 ranch vein occlusion (BVO), a common retinal vascular disorder, on protein tyrosine phosphorylation,

119 elp to identify therapeutic targets to treat vascular disorders or to promote or inhibit vessel growt

120 tastatic malignancies (OR = 2.1), peripheral vascular disorders (OR = 1.8), alcohol abuse (OR = 1.8),

121 nflammatory disorders, ocular tumor, retinal vascular disorders, other, normal, and unknown.

122 he marked up-regulation of TRPC6 observed in vascular disorders, our findings suggest that attenuatio

123 ura-has been identified as a risk factor for vascular disorders, particularly in women, but because o

124 cular or optic nerve head ischemic or ocular vascular disorders previously thought to be manifestatio

125 (BMPR-II) underlie the inherited form of the vascular disorder primary pulmonary hypertension (PPH).

126 Porto-sinusoidal vascular disorder (PSVD) is a rare and commonly overlook

127 quired in all patients with porto-sinusoidal vascular disorder (PSVD).

128 er, other neurological disorders, peripheral vascular disorders, pulmonary circulation disorders, ren

129 get for clinical assessment and treatment of vascular disorders resulting from atherosclerosis.

130 The 5 major categories of NNUMS were retinal vascular disorders, rhegmatogenous retinal detachment, r

131 %] of 94 patients), seizure (five [5%]), and vascular disorders (six [6%]).

132 The most common severe adverse events were vascular disorders (standard of care three [3%] of 90, d

133 enotypic switching of VSMCs is a hallmark of vascular disorders such as atherosclerosis and restenosi

134 Vascular disorders such as atherosclerotic diseases larg

135 on is associated with the pathophysiology of vascular disorders such as hypertension, atherosclerosis

136 n and is associated with a broad spectrum of vascular disorders such as impaired angiogenesis.

137 ls (hiPSCs) has great potential for treating vascular disorders such as ischemic retinopathies.

138 te sites for paracentesis, and to assess for vascular disorders such as portal vein or hepatic vein t

139 gen sulfide as a novel therapeutic agent for vascular disorders such as preeclampsia.

140 y in sEng release and its pathogenic role in vascular disorders such as preeclampsia.

141 Little is known about autophagy in other vascular disorders, such as aneurysm formation, arterial

142 m contributes to the pathogenesis of several vascular disorders, such as atherosclerosis, restenosis,

143 underlying angiogenesis, arteriogenesis, and vascular disorders, such as HHT and pulmonary hypertensi

144 ion of a pre-existing or concomitant hepatic vascular disorder superimposed and exacerbated by gas bu

145 butes to cerebral cavernous malformations, a vascular disorder that affects low-perfused brain venous

146 Cerebral small vessel disease (SVD) is a vascular disorder that increases the risk of stroke and

147 ely, although less prevalent, there are many vascular disorders that typically involve only a single

148 cular or optic nerve head ischemic or ocular vascular disorders, the ophthalmologist should talk to t

149 ted in conditions ranging from developmental vascular disorders to age-related neurodegenerative dise

150 ur (2%) of 167 patients had grade 3 or worse vascular disorders, two (1%) had gastrointestinal disord

151 ic molecule that prevents the development of vascular disorders when administered prophylactically.

152 monary hypertension, a progressive pulmonary vascular disorder with high morbidity and mortality.

153 orrhagic telangiectsia (HHT) is an inherited vascular disorder with highly variable expressivity, aff

154 utations in other genes for HHT and possibly vascular disorders with overlapping phenotypes.