ライフサイエンスコーパス: vascularization

1 lopment (hyaloid regression, but not retinal vascularization).

2 e interconnectivity, axonal orientation, and vascularization.

3 le parallels to the regulation of vertebrate vascularization.

4 omologous to vertebrate factors that control vascularization.

5 losely related to inflammation, hypoxia, and vascularization.

6 crosing cells as a function of heterogeneous vascularization.

7 of CAFs to deform the matrix and suppressed vascularization.

8 ch are derived from vascular initials during vascularization.

9 g to excessive cellular consumption and poor vascularization.

10 ing cells can enhance the potency of EVs for vascularization.

11 ed intratumoral expression of VEGF and tumor vascularization.

12 ion of nutrients and oxygen and induce tumor vascularization.

13 ccelerated tumorigenesis while also altering vascularization.

14 k rarefaction with decreased choriocapillary vascularization.

15 se, which was a feature of module-associated vascularization.

16 rmed to determine the absence or presence of vascularization.

17 e channels, which we termed primitive myxoid vascularization.

18 ally-inhibited CAFs showed partial rescue of vascularization.

19 nation in human GBM, despite increased tumor vascularization.

20 e brain increases HIF-1alpha/VEGF levels and vascularization.

21 in vitro and in vivo and inhibited xenograft vascularization.

22 on and tumor cell killing, and altered tumor vascularization.

23 , and a link between T cell infiltration and vascularization.

24 of biochemical events related to healing and vascularization.

25 ture system as a platform for studying tumor vascularization.

26 plex interplay between hormone secretion and vascularization.

27 ovasculature, resulting in an improved early vascularization.

28 issue formation and remodeling, and to tumor vascularization.

29 fusion limitations and facilitating adequate vascularization.

30 s to overcome the effects of hypoxia or poor vascularization.

31 impaired wound closure and compromised wound vascularization.

32 olved in extracellular matrix remodeling and vascularization.

33 an promote angiogenesis, which improves bone vascularization.

34 roperties, mitigation of host responses, and vascularization.

35 ed improved wound closure and improved wound vascularization.

36 ed the impact of background pigmentation and vascularization.

37 ked reductions in hyperplasia, dysplasia and vascularization.

38 bone grafting is the lack of sufficient bone vascularization.

39 angiogenesis in both physiological and tumor vascularization.

40 ice led to diminished SK lesions and corneal vascularization.

41 nt of mucogingival defects by inducing local vascularization.

42 that facilitates rapid restoration of islet vascularization.

43 tumor microenvironment because of inadequate vascularization.

44 ly induced tumors that also display enhanced vascularization.

45 gnaling, which can promote MM-induced marrow vascularization.

46 ps had improved skin perfusion and increased vascularization.

47 transfer through oxygen supplementation and vascularization.

48 phosphate scaffolds with or without surgical vascularization.

49 Cs and can be developed as a biomaterial for vascularization.

50 oss metazoans, it controls tubulogenesis and vascularization.

51 n impaired lung development and dysregulated vascularization.

52 nesis in correlation with tissue hypoxia and vascularization.

53 or pharmacokinetics, dense fibrosis and hypo-vascularization.

54 idly as the wild-type tumors and had similar vascularization.

55 ar whether they are also implicated in islet vascularization.

56 and simultaneously augmenting graft and host vascularization.

57 sults in sustained suppression of pathogenic vascularization.

58 cers (2), graft infection (2), and interface vascularization (4).

59 cific targeting, we observed decreased tumor vascularization, a switch in the metabolic program of MA

60 e recurrence brought upon in-part by delayed vascularization accompanied by overactive inflammatory r

61 lop a safe and effective therapy for corneal vascularization, adeno-associated virus (AAV) gene thera

62 splayed greater MDSC infiltration, increased vascularization and accelerated tumor growth.

63 e previously noted that the impaired retinal vascularization and an inability to undergo pathologic n

64 is responsible for the early phases of brain vascularization and BBB differentiation.

65 ing it an ideal monocot model for addressing vascularization and biomass deposition.

66 ceptor complex is required for developmental vascularization and BRB formation.

67 Yet, ROs lack vascularization and cannot recapitulate the important ph

68 thelial cell (EC) plasticity drives aberrant vascularization and chemoresistance in glioblastoma mult

69 occurred in 44% (11/25; P = 0.001), corneal vascularization and conjunctivalization in 24% (6/25; P

70 hat had to be removed after 2 years owing to vascularization and corneal thinning.

71 s had reduced terminal air sac formation and vascularization and delayed distal epithelial differenti

72 Vascularization and efficient perfusion are long-standin

73 a reveal that Egfl7 is crucial for placental vascularization and embryonic growth, and may provide in

74 ecific deletion of YAP/TAZ leads to impaired vascularization and embryonic lethality.

75 Possibilities of integrating vascularization and encapsulation in bioprinted tissues

76 ammatory macrophages promoted HIF-associated vascularization and expression of the immunosuppressive

77 ECs, through the AGO1-TSP1 pathway, control vascularization and function of adipose tissues, insulin

78 pe (wt) pigs were used to analyze myocardial vascularization and function.

79 ls plays a pivotal role in maintaining islet vascularization and function.

80 s and morphology can enhance in vitro tissue vascularization and graft integration prospects.

81 with pulmonary lesions, which reflected high vascularization and greater tumor-associated macrophage

82 een reported to critically account for tumor vascularization and growth in mouse tumor experimental m

83 ablation of sprouting ECs diminished tumour vascularization and growth without compromising vascular

84 , which may contribute to an impaired lesion vascularization and growth.

85 ic endothelial cells (LECs) to support tumor vascularization and growth.

86 Vascularization and immune cell infiltration were promin

87 c effect likely as a result of earlier islet vascularization and improved islet engraftment.

88 rily a result of the alteration of placental vascularization and improved maternal metabolism.

89 t-term cultured constructs demonstrated poor vascularization and increased thrombus formation.

90 procedure to investigate bone regeneration, vascularization and infection prevention in response to

91 LA-G to safely and effectively treat corneal vascularization and inhibit fibrosis while alluding to b

92 nd invasive MDA-MB-231 tumors display higher vascularization and less mature ECM, significantly enhan

93 The ability to induce substantial vascularization and morphological maturation of kidney o

94 s of exercise on fetal overgrowth, placental vascularization and nutrient transporters were analysed.

95 reatments that have a direct effect on tumor vascularization and perfusion.

96 The distal vagina also showed increased vascularization and perivascular fibers containing NPY.

97 prognosis-implicate XBP1s in promoting tumor vascularization and progression.

98 in endothelial cells to enable intracerebral vascularization and proper expression of molecular marke

99 nate-pretreated hMSC enhanced wound closure, vascularization and re-epithelialization and confirmed t

100 splanted Bbs4(-/-) islets exhibit delayed re-vascularization and reduced vascular fenestration after

101 arge bone defects is limited by insufficient vascularization and slow bone regeneration.

102 l tubulogenesis program, broadly adapted for vascularization and specifically coopted for biominerali

103 othelial growth factor (VEGF) to enhance jaw vascularization and stabilize the major mandibular arter

104 inding was associated with an impaired early vascularization and stromal tissue growth as well as red

105 Recent studies have demonstrated the vascularization and subsequent maturation of human pluri

106 ate a mechanism that controls aberrant tumor vascularization and suggest that targeting Endo-MT may o

107 t to gain insights into the process of brain vascularization and the pathogenesis of Fowler syndrome

108 formation, thus informing future studies of vascularization and tissue engineering applications.

109 ssful bone repair also depends on sufficient vascularization and to address this challenge, novel str

110 Islet grafts were assessed for the degree of vascularization and total cellular insulin content.

111 he obesity-dependent tumour ASC recruitment, vascularization and tumour growth promotion.

112 ndothelial cell primary cilia regulate islet vascularization and vascular barrier function via the VE

113 fibrotic group had marked bleb scarring and vascularization and worse logMAR visual acuity.

114 ation of this adhesion inhibitor allowed for vascularization and wound healing, and maintained local

115 ding suppressing immune responses, promoting vascularization and, consequently, augmenting tumor prog

116 PPAR-gamma protein expression and placental vascularization and, if so, to evaluate the effectivenes

117 vo with regard to left ventricular function, vascularization, and amelioration of apoptosis and hyper

118 for effectors associated with inflammation, vascularization, and bone formation.

119 yperplasia, epicardial activation, increased vascularization, and causes cardiomegaly through persist

120 relationship between TAM infiltration, tumor vascularization, and corresponding drug delivery by usin

121 influenced by baseline PED height, degree of vascularization, and drug type.

122 marker gene expression, marked reduction of vascularization, and excessive apoptotic staining in unr

123 types are responsible for matrix deposition, vascularization, and injury response.

124 smaller histological lesions, reduced tumor vascularization, and less lung metastases.

125 cantly reduced immunosuppression, intratumor vascularization, and local and metastatic breast cancer

126 duration of stay in the ICU, M2 macrophages, vascularization, and pancreatic cell replication.

127 load dose of PolyhHb influences growth rate, vascularization, and regional blood flow in the FME and

128 , differentiation/proliferation, metabolism, vascularization, and reproduction.

129 on, matrix remodeling, cell differentiation, vascularization, and steroid metabolisms in mice.

130 umerous factors mediating follicular growth, vascularization, and ultimately oocyte release via folli

131 odeling and have promise as therapeutics for vascularization applications.

132 Several pre-vascularization approaches have been developed to increa

133 The results suggest that mineralization and vascularization are coupled by localized secretion of pa

134 Current treatments of corneal vascularization are limited in efficacy and elicit undes

135 Three patterns of rhizophore vascularization are present in Selaginella and each is c

136 al to mesenchymal transition (EMT) and wound vascularization are two critical interrelated processes

137 ency of DPC from balding scalps in fostering vascularization around the hair follicle may contribute

138 VEGF receptor that mediates endothelial cell vascularization, as a mutant p53 transcriptional target

139 iposity, with a parallel increase in adipose vascularization associated with reduced circulating none

140 A rapid and stable bone vascularization at an early stage of implantation is ess

141 oxia disrupted pulmonary alveolarization and vascularization at PND 21; however, there were no differ

142 hil-T cell interactions in the regulation of vascularization at the maternal-fetal interface.

143 e cell delivery system utilizing appropriate vascularization at the site of cell implantation that re

144 e employed to enhance endothelial-derived EV vascularization bioactivity.

145 Extracellular matrix is known to regulate vascularization by a sequence of multiple factors includ

146 have been shown to regulate wound and tumor vascularization by different mechanisms.

147 chambers in nude mice, cardiopatches undergo vascularization by host vessels and continue to fire Ca(

148 t mice showed significantly enhanced hepatic vascularization by micro-computed tomography and histolo

149 through the induction of angiogenesis, tumor vascularization can occur through the nonangiogenic mech

150 f green fluorescent protein(+)/Tie2(+) EPCs, vascularization, cell proliferation, and apoptosis were

151 )/Tie2(+) EPCs, numbers of circulating EPCs, vascularization, cell proliferation, apoptosis, and immu

152 e, evaluated by tumor-to-blood [T/B] ratio), vascularization (cerebral blood volume [CBV]), and vascu

153 llowing stroke while increasing peri-infarct vascularization compared to nonporous hydrogel controls

154 sical GBM subtypes significantly reduced GBM vascularization compared with controls.

155 receptor and AKT and reduced decreased tumor vascularization compared with vehicle.

156 BUT), conjunctival congestion, corneal haze, vascularization, conjunctivalization, and limbal stem ce

157 Angiogenesis inhibitors, acting on tumor vascularization, counteract this tumor-host energy imbal

158 A8, and S100A9), increased oxidative stress, vascularization (CYR61), and skin repair events (KRT6A,

159 Retinal vascularization defects are phenocopied by inducible ina

160 isolated adult mutant retinas did not reveal vascularization defects.

161 We found that the cerebral vascularization deficit of nft (y72) mutants is caused b

162 ffeine did not interfere with normal retinal vascularization development but selectively protected ag

163 hat sea urchin spiculogenesis and vertebrate vascularization diverged from a common ancestral tubulog

164 These data suggest that impaired ischemic vascularization does not necessarily associate with supp

165 r 1.5 million individuals suffer from cornea vascularization due to genetic and/or environmental fact

166 t the level of the optic nerve and choroidal vascularization during acute IOP changes.

167 Poor vascularization during adipose tissue proliferation caus

168 cartilages undergo extensive remodeling and vascularization during juvenile stages to generate fat-f

169 ted delayed granulation tissue formation and vascularization during skin-wound healing in AD-HIES pat

170 revealed similar results, with a decrease in vascularization during therapy.

171 nd sacculi formation accompanied by impaired vascularization, excessive epithelial cell death, reduce

172 Vascularization, fibrin depositions, macrophage and neut

173 ed AnaLysis ; GE Healthcare, Milwaukee, Wis) vascularization flow index ( VFI vascularization flow in

174 interval ]: 0.90, 0.98) versus 0.899 for VFI vascularization flow index (95% CI confidence interval :

175 e interval : 0.82, 0.97) versus 0.67 for VFI vascularization flow index (95% CI confidence interval :

176 aukee, Wis) vascularization flow index ( VFI vascularization flow index ).

177 actional moving blood volume values than VFI vascularization flow index for intra- and interobserver

178 oving blood volume performed better than VFI vascularization flow index in repeatability studies.

179 FMBV fractional moving blood volume and VFI vascularization flow index produced significantly differ

180 Linear regression of VFI vascularization flow index versus FMBV fractional moving

181 Mean VFI vascularization flow index was 2.26 +/- 0.96 (range, 0.1

182 Incomplete vascularization following IVB is very common and is asso

183 Owing to the importance of vascularization for the clinical applicability of tissue

184 cluding biomineralization and interestingly, vascularization genes.

185 After vascularization, glomerular structures in the organoid d

186 pplicable strategy for stable and functional vascularization has remained challenging.

187 At early postnatal stages with low GZ vascularization, Hif1alpha restrains CGN-progenitor cell

188 d in significantly earlier normoglycemia and vascularization, improved glucose tolerance, and increas

189 demonstrated increased integrin activity and vascularization in B16-F10-luc melanoma tumors, as demon

190 Wound instability and poor functional vascularization in bone tissue engineering lead to lack

191 ions, color Doppler US failed to demonstrate vascularization in four (33.3%) lesions, which were posi

192 died the molecular signals supporting kidney vascularization in host lymphoid sites and omenta.

193 flow, decreased tumor growth, and decreased vascularization in hypoxic tumors.

194 In this study, we assessed wound and tumor vascularization in mice with genetic ablation of both in

195 the contribution of Ocys to enhanced marrow vascularization in MM is unclear.

196 We document rhizophore vascularization in nine Selaginella species using cleare

197 ise intervention reverses impaired placental vascularization in obese mice.

198 h improved maternal metabolism and placental vascularization in obese mothers with exercise.

199 live imaging we observed reduced OF hyaloid vascularization in pax2a(-/-) embryos.

200 apeutic nanoparticle delivery but not higher vascularization in pulmonary tumors.

201 s and source of endothelial cells to promote vascularization in regenerative strategies.

202 Vascularization in response to anti-vascular endothelial

203 parisons with the architecture of rhizophore vascularization in Selaginella.

204 flow, providing a new target for modulating vascularization in the clinic.

205 tered immune cell responsiveness and reduced vascularization in the heart.

206 del of vasculogenesis, we observed increased vascularization in the presence of breast cancer CAFs co

207 OCT angiography was used to measure retinal vascularization in the treated eye compared with the fel

208 NFalpha enhanced immune activity and altered vascularization in the tumor bed.

209 Norrin signaling to accelerate inner retinal vascularization in wild-type animals, but not in the ret

210 cular endothelial growth factor A and, thus, vascularization, increased placental fetal capillary vol

211 Quantitative parameters (vascularization index and fractional moving blood volume

212 Initial US echogenicity and vascularization influence the ablation outcome.

213 of scAAV8G9-optHLA-G1 + G5 prevented corneal vascularization, inhibited trauma-induced T-lymphocyte i

214 Aberrant vascularization is a hallmark of cancer progression and

215 Islet vascularization is essential for intact islet function a

216 extended follow-up is needed because retinal vascularization is usually incomplete.

217 Lid margins were evaluated for scales, vascularization, Marx line, expressibility and quality o

218 ng in a rabbit model, resulting in increased vascularization, more mature collagen fiber organization

219 In vivo implantation suggests vascularization of 3D bioprinted cardiac patches with en

220 f endometriosis: they dictate the growth and vascularization of endometriosis lesions and more recent

221 developing blood vessels contributes to the vascularization of endometriotic lesions.

222 (EPCs) into microvessels contributes to the vascularization of endometriotic lesions.

223 The requirement for immediate vascularization of engineered dental pulp poses a major

224 lar peritubular cells, via PEDF, may prevent vascularization of human seminiferous tubules.

225 marrow stem/progenitor cells that accelerate vascularization of ischemic areas.

226 Vascularization of ischemic skeletal muscle, as well as

227 gen gel (MCG) dressing demonstrated improved vascularization of ischemic wounds and better healing ou

228 how that CNS-resident radial glia direct the vascularization of neighboring tissues during developmen

229 served transient neurotransmission and early vascularization of neural crest cell (NCC)-derived periv

230 port that Nck is required for the growth and vascularization of primary tumors and lung metastases in

231 HO-1 inhibition by SnPP reduced growth and vascularization of RMS tumors in vivo accompanied by ind

232 injury, and showed significantly attenuated vascularization of sponge implants.

233 Growth and vascularization of subcutaneous tumor allografts was enh

234 ults showed a significantly higher degree of vascularization of the callus than of the healthy perios

235 e of this intercellular communication is the vascularization of the central nervous system (CNS), whi

236 Vascularization of the damaged tissue and prevention of

237 erficial retinal vascular layer and aberrant vascularization of the deep vascular plexus and central

238 pertrophic chondrocyte apoptosis and impairs vascularization of the growth plate.

239 mpletely blocking the vascular drive for the vascularization of the immature retina.

240 In addition to vascularization of the lens through a capsular dehiscenc

241 on, inflammation, fibrous encapsulation, and vascularization of the material.

242 ducible knockout approach to study postnatal vascularization of the mouse brain.

243 bit intravitreal angiogenesis and facilitate vascularization of the previously avascular retina, whic

244 xamine the effect of Bcl-2 expression during vascularization of the retina, we assessed its contribut

245 examine the development and consequences of vascularization of the tuberculous granuloma in the zebr

246 The inefficient vascularization of tumor tissue also limits the penetrat

247 l growth factor isoform A (VEGF-A) and islet vascularization on beta-cell function and survival using

248 ry (P = 0.03), persistent or increased tumor vascularization on the interim PET (DeltaBF cutoff = -30

249 icant effect of ferrogel actuation on muscle vascularization or perfusion was found.

250 OCTA is a promising tool to evaluate the vascularization or revascularization of conjunctiva, con

251 ntrolled the release of VEGF, which promotes vascularization, or dexamethasone, an anti-inflammatory

252 evident at time points preceding periosteal vascularization, ossification, and mineralization.

253 NS-resident progenitors in the regulation of vascularization outside the CNS, serving as a paradigm f

254 Accurate assessment of hypoxia and vascularization over space and time is critical for unde

255 c volume, urethral volume, and genitourinary vascularization over time in response to estradiol-induc

256 g suture removal (P = .01), and suture-tract vascularization (P = .04) significantly influenced posto

257 allows for a comprehensive evaluation of the vascularization pattern and efficiency of biomaterials.

258 Hippocampal vascularization patterns have been categorized into a mi

259 giography we manually classified hippocampal vascularization patterns in older adults with and withou

260 We hypothesized, that hippocampal vascularization patterns may be important trait markers

261 n may activate endothelial EVs towards a pro-vascularization phenotype, which could have implications

262 Incomplete vascularization posterior to zone 3 was common (71.6% of

263 Cellular microbeads showed vascularization potential comparable to bulk cellular hy

264 en-deficient mice severely impaired fracture vascularization, precluded bone union, and resulted in r

265 After retreatment with IVB, retinal vascularization proceeded minimally and slowly.

266 As vascularization proceeds, these inhibitory mechanisms ar

267 ess of tumor has been associated to its high vascularization rate.

268 Graft vascularization remains one of the most critical challen

269 e ability of endothelial EVs to induce a pro-vascularization response.

270 ng Tauber staging), central corneal disease (vascularization, scarring, ulceration, and conjunctivali

271 ge at infancy, visual acuity, current retina vascularization status, vitreous character, presence of

272 where L1-DeltaTM levels correlate with tumor vascularization, supporting the involvement of NOVA2-med

273 transplantation significantly enhances graft vascularization, survival, and proliferation of grafted

274 transplantation significantly enhances graft vascularization, survival, proliferation, and the densit

275 Therefore, germinal zone vascularization sustains NPC proliferation in the prenat

276 a frequently overlooked mechanism of tumour vascularization that can influence disease progression,

277 l Glrx transgenic mice had impaired ischemic vascularization, the effects of cell-specific Glrx overe

278 erentially affected primary tumor growth and vascularization; these varying effects were associated w

279 or less (P < 0.05) and in eyes with furthest vascularization to posterior zone 2 eyes compared with z

280 tivities, and enhanced cell infiltration and vascularization upon in vivo implantation.

281 ility to selectively target tumor growth and vascularization using tubulin-destabilizing agents.

282 patches were transplanted in rats, and their vascularization was assessed.

283 ral role for apelin/APLNR in controlling GBM vascularization was corroborated in a serial implantatio

284 Also, the anterior extent of retinal vascularization was decreased (mean, 1.76 disc diameters

285 s [DD] vs. 4.48 DD), and the rate of retinal vascularization was delayed (mean, 0.11 DD/week vs. 0.23

286 Such augmentation of skeletal muscle vascularization was found to be bolstered via Silent inf

287 compared with WT; however, adaptive cardiac vascularization was increased in some mutant mice and re

288 Furthermore, tumor vascularization was increased in the Sharpin (cpdm) mice

289 ce-like corneal opacities, prominent corneal vascularization was present in 2 patients mimicking inte

290 clera was not affected, and the conjunctival vascularization was restored at 1 month.

291 Pulmonary alveolarization and vascularization were analyzed at postnatal day (PND) 21.

292 Islet graft morphology and vascularization were evaluated by immunohistochemistry.

293 oxamine (DFO) has been shown to improve skin vascularization when injected into radiated tissue prior

294 nduced doppel overexpression in ECs enhanced vascularization, whereas doppel constitutively colocaliz

295 es pro-angiogenic factors that promote tumor vascularization, which in turn enhances drug delivery an

296 B) patients have complex structures and poor vascularization, which obstructs drug distribution to th

297 efore providing a physiological platform for vascularization, which we call 'Organ-On-VascularNet'.

298 NA methylation are a feature of sorghum root vascularization, which we confirmed using tissue-specifi

299 that THSD7A expression begins on glomerular vascularization with slit diaphragm formation in develop

300 showed similar tendencies toward decreasing vascularization, with a stronger decrease in tumors trea