ライフサイエンスコーパス: vasculogenic

1 Here we investigated whether they are also vasculogenic.

2 fferent, and this significantly affected the vasculogenic ability and quality of the vessel networks.

3 er, there has been controversy regarding the vasculogenic ability of BM cells.

4 play opposite roles in the regulation of the vasculogenic ability of TNBC, acting as facilitator and

5 cell populations have higher angiogenic and vasculogenic activities.

6 We tested hemangioma-derived stem cells for vasculogenic activity in vivo after implantation into im

7 anded safely ex vivo, and can produce robust vasculogenic activity in vivo.

8 differentiation potential, and inhibits the vasculogenic activity of these cells in vivo.

9 s (EPCs) have the required proliferative and vasculogenic activity to create vascular networks in viv

10 urther sought to determine the comprehensive vasculogenic and angiogenic characteristics of human and

11 We show that this process involves both vasculogenic and angiogenic elements, including an initi

12 ough tissue-specific signalling activated by vasculogenic and angiogenic factors and deposition of ma

13 omplex morphogenetic process, requiring both vasculogenic and angiogenic mechanisms.

14 in the neuroepithelium where they generated vasculogenic and hemogenic foci.

15 , adventitial Sca-1(+)CD45(+) cells are also vasculogenic and may be a source of vasa vasorum during

16 Derivation of vasculogenic and multipotent pericytes from hPSC can be

17 We studied vasculogenic and nonvasculogenic intracranial murine gli

18 ived hematopoietic stem/progenitor cells are vasculogenic and play an important role in endothelial h

19 hind limb ischemia model to test angiogenic-vasculogenic and therapeutic effects.

20 ious in vitro endothelial differentiation or vasculogenic assays were conducted.

21 Then we test vasculogenic capacity of various cell types using a micr

22 D31 is a novel marker of a circulating angio-vasculogenic cell population and to establish the cells'

23 ct in vivo reprogramming of fibroblasts into vasculogenic cell states and identify a series of questi

24 Together, our results suggest that vasculogenic cell therapies based on nanotransfection-dr

25 Although progenitor-based vasculogenic cell therapies have shown promise as a pote

26 opment of vasculogenic models using multiple vasculogenic cell types for basic research and drug scre

27 Vasculogenic cell-based therapy combined with tissue eng

28 D31(+) cells represent highly angiogenic and vasculogenic cells and can be a novel and highly promisi

29 ive, we demonstrate that bone marrow-derived vasculogenic cells exhibit enhanced angiogenic functions

30 s antibodies inhibit epithelial migration of vasculogenic cells from the proepicardium.

31 e serosal mesothelium is the major source of vasculogenic cells in developing mouse gut.

32 examine the development of hematopoietic and vasculogenic cells in normal zebrafish and characterize

33 ieved by either direct targeting of putative vasculogenic cells in the proepicardium in ovo or taggin

34 ological significance of bone marrow-derived vasculogenic cells in the response to injury during tran

35 Efficient generation of competent vasculogenic cells is a critical challenge of human indu

36 how that, in this model, bone marrow-derived vasculogenic cells primarily contribute to the formation

37 cing the contribution of bone marrow-derived vasculogenic cells to transplantation sites may help to

38 vo reprogramming of fibroblasts into induced vasculogenic cells was not reported until 2017.

39 esets' these endothelial cells to adaptable, vasculogenic cells, which form perfusable and plastic va

40 mangioma-derived stem cell population, human vasculogenic cells, which we had previously discovered.

41 r that designates circulating angiogenic and vasculogenic cells.

42 y of these vessels is likely to have a large vasculogenic component.

43 These results uncover a SHF vasculogenic contribution to coronary lymphatic developm

44 g embryonic lethality; brain hemorrhage; and vasculogenic, craniofacial, and neural tube defects in m

45 To define vasculogenic developmental pathways and enhance differen

46 pulations have been shown to overexpress the vasculogenic differentiation markers CD144 (VE-cadherin)

47 generation of functional blood vessels upon vasculogenic differentiation of DPSCs.

48 actor (VEGF) on the extent of osteogenic and vasculogenic differentiation of human mesenchymal stem c

49 ormal embryos that the arch arteries form by vasculogenic differentiation of pharyngeal mesoderm.

50 resulted in highest extent of osteogenic and vasculogenic differentiation of the encapsulated hMSCs a

51 ts shed light on the dual cardiomyogenic and vasculogenic effects of PLGF during heart development.

52 (DPSCs) can be induced to differentiate into vasculogenic endothelial (VE) cells.

53 We conclude that vasculogenic endothelial cells and nascent vessels are c

54 Vascular density and the expression of vasculogenic factors were reduced as a result of MO but

55 reb1 led to a reduction in the expression of vasculogenic factors, cardiovascular defects, and embryo

56 nhanced tissue perfusion, wound closure, and vasculogenic fibroblast contribution to perfused vessels

57 e was sufficient to restore FLI1 expression, vasculogenic fibroblast emergence, tissue perfusion, and

58 adaptive response mechanism that produces a vasculogenic fibroblast state change opens new avenues f

59 Vasculogenic fibroblast subset emergence was blunted in

60 2, Foxc2, and Fli1 (EFF) plasmids increasing vasculogenic fibroblasts (VF) and promoting vascularizat

61 From E10.5 to E13.5, these vasculogenic foci were a source of new blood vessel form

62 ator of LPS-induced downstream angiogenic or vasculogenic genes.

63 n animals for more than 4 weeks, after which vasculogenic, geometric, and functional parameters were

64 dothelial growth factor (VEGF) expression by vasculogenic glioma cells and spontaneously arising vasc

65 hat CUL2 is required for expression of other vasculogenic HIF targets.

66 nes (such as EphA2 and VE-cadherin) and form vasculogenic-like networks when cultured on a three-dime

67 MP-2) activity, critical in the formation of vasculogenic-like networks.

68 enotypic changes associated with aggressive, vasculogenic melanoma cells.

69 migrating epithelial epicardium, delaminated vasculogenic mesenchyme and vascular smooth muscle cells

70 stained the functions of both osteogenic and vasculogenic microgels and enhanced one another.

71 On the other hand, the vasculogenic microgels containing only gelatin, enriched

72 Vasculogenic mimicry (VM) describes the unique ability o

73 er (NSCLC), its linkage to alteration of the vasculogenic mimicry (VM) formation to influence the NSC

74 Vasculogenic mimicry (VM) is a recently discovered angio

75 A growing body of evidence shows that vasculogenic mimicry (VM) is closely related to the inva

76 Vasculogenic mimicry (VM) is the phenomenon whereby non-

77 s found in patient tumor slices displaying a vasculogenic mimicry (VM) phenotype.

78 Tumor cell vasculogenic mimicry (VM) refers to the plasticity of ag

79 l cell carcinoma (ccRCC), its role to impact vasculogenic mimicry (VM) to alter the ccRCC progression

80 E-cadherin) and cytokeratins consistent with vasculogenic mimicry (VM), a process whereby tumour cell

81 display the ability to drive blood-perfused vasculogenic mimicry (VM), an alternative microvascular

82 in) and TIE1 and are associated with CD31(-) vasculogenic mimicry (VM), an established biomarker asso

83 alpha expression and an increase in CD144(+) vasculogenic mimicry (VM), leading to formation of chann

84 Vasculogenic mimicry (VM), the formation of matrix-rich

85 -2 expression with known prognostic factors, vasculogenic mimicry (VM), the mature vasculature (von W

86 nd participate in a PECAM1-dependent form of vasculogenic mimicry (VM).

87 ng vessel-like channels, a phenomenon termed vasculogenic mimicry (VM).

88 ternative microvascular circulation known as vasculogenic mimicry (VM).

89 In addition, Notch4 function in vasculogenic mimicry and anchorage-independent growth in

90 an essential role during the acquisition of vasculogenic mimicry and angiogenic properties associate

91 events that regulate the process of melanoma vasculogenic mimicry and identify new signal transductio

92 he ability of these tumor cells to engage in vasculogenic mimicry and neovascularization.

93 overexpressed in glioma, glioma stem cells, vasculogenic mimicry and neovasculature.

94 /or its cleavage fragments, are required for vasculogenic mimicry by aggressive melanoma cells.

95 In this study, we found that BPIFB1 inhibits vasculogenic mimicry by regulating the metabolic reprogr

96 Vasculogenic mimicry describes a process where aggressiv

97 tumors because of their ability to implement vasculogenic mimicry during hypoxia.

98 r gene involved in regulating glycolysis and vasculogenic mimicry in NPC.

99 Vasculogenic mimicry is posited to contribute to melanom

100 lular and molecular determinants of melanoma vasculogenic mimicry is presented.

101 Mig-7 protein primarily co-localized with vasculogenic mimicry markers factor VIII-associated anti

102 highly invasive uveal melanoma cells forming vasculogenic mimicry patterns after exposure to a lamini

103 tissue samples, uveal melanoma cells within vasculogenic mimicry patterns assumed the spindle A morp

104 s of primary uveal melanomas lacking looping vasculogenic mimicry patterns either did not stain for o

105 The histological detection of laminin-rich vasculogenic mimicry patterns in human primary uveal mel

106 on of human rather than mouse laminin in the vasculogenic mimicry patterns in this model demonstrates

107 Thus, the generation of vasculogenic mimicry patterns is accompanied by dampenin

108 Vasculogenic mimicry patterns were reconstructed from se

109 highly invasive uveal melanoma cells forming vasculogenic mimicry patterns, and genes associated with

110 Vasculogenic mimicry patterns, composed of human laminin

111 In primary melanomas containing looping vasculogenic mimicry patterns, strong osteopontin staini

112 After forming vasculogenic mimicry patterns, uveal melanoma cells inva

113 Imaging revealed a vasculogenic mimicry phenotype in NGFR(hi) tumor cells w

114 ith their increased invasion, migration, and vasculogenic mimicry plasticity.

115 echanical and molecular events that regulate vasculogenic mimicry provide opportunities for the devel

116 The unique patterning characteristic of vasculogenic mimicry provides an opportunity to design n

117 an carcinoma cells could engage in molecular vasculogenic mimicry reflected by their plasticity, comp

118 We recently have introduced the term vasculogenic mimicry to describe the unique ability of a

119 Recently, the term "vasculogenic mimicry" has been used by our laboratory an

120 egulated, aggressive tumor cells was termed "vasculogenic mimicry" to emphasize their de novo generat

121 y to form tube-like structures on collagen ("vasculogenic mimicry").

122 osome nucleation, motility, neoangiogenesis, vasculogenic mimicry, and osteoclastogenesis in the abse

123 MEF2C was found to mediate VEGF-induced vasculogenic mimicry, angiogenesis and migration/invasio

124 lial-cadherin, which plays a pivotal role in vasculogenic mimicry, as well as interleukin-8, fibronec

125 erized to invade aggressively and to undergo vasculogenic mimicry, expressed Mig-7.

126 EF2C on cell proliferation, and VEGF-induced vasculogenic mimicry, migration/invasion as well as angi

127 aggressive melanoma cells to participate in vasculogenic mimicry, particularly their expression of e

128 y human melanoma cells in vivo and in vitro: vasculogenic mimicry," by Maniotis and colleagues, which

129 rs have recently described a process termed "vasculogenic mimicry," which consists of the formation o

130 These data indicate that vasculogenic mimicry-like laminin networks, in addition

131 l of histone and decreases the expression of vasculogenic mimicry-related genes, VEGFA, VE-cadherin,

132 cell invasion, migration, and inhibition of vasculogenic mimicry.

133 ddition to tumor cell plasticity as shown by vasculogenic mimicry.

134 adapted to a pseudoendothelial phenotype in vasculogenic mimicry.

135 vascular channels without EC, referred to as vasculogenic mimicry.

136 sis that VE-cadherin is critical in melanoma vasculogenic mimicry.

137 in tyrosine kinases are involved in melanoma vasculogenic mimicry.

138 may not be applicable to tumors that express vasculogenic mimicry.

139 MP2, ultimately leading to the inhibition of vasculogenic mimicry.

140 on, invasion, adhesion, colony formation and vasculogenic mimicry.

141 noma mitogen, laminin, a phenomenon known as vasculogenic mimicry.

142 ell dissemination by increasing invasion and vasculogenic mimicry.

143 remodeling to form the specific mechanism of vasculogenic mimicry; we also summarized some of the cur

144 from hPSC can be used for the development of vasculogenic models using multiple vasculogenic cell typ

145 ial cells, which form a primitive, patterned vasculogenic network.

146 es in vitro), that mimics endothelial-formed vasculogenic networks and correlates with poor clinical

147 lanoma cells abrogated their ability to form vasculogenic networks and directly tested the hypothesis

148 imensional culture, which "mimics" embryonic vasculogenic networks formed by differentiating endothel

149 Motivated by the structure and function of vasculogenic networks, we predict how measures of networ

150 studies in men with erectile dysfunction of vasculogenic, neurogenic, psychogenic, and mixed causes.

151 ibution of the second heart field (SHF) to a vasculogenic niche composed of AMCs and sub-mesothelial

152 usion recovery and arteriogenesis, preserved vasculogenic paracrine signaling from myofibers, increas

153 Vasculogenic pathways are unexplored targets for the tre

154 grammed bone marrow progenitors toward a pro-vasculogenic phenotype that was positive for c-Kit, the

155 behavior and identifies the "mesenchymal-to-vasculogenic" phenotypic transition as an essential step

156 The vasculogenic potential of adult BM-derived cells and the

157 Although the vasculogenic potential of circulating and cord blood (CB

158 ion of IL-6 or STAT3 signaling decreases the vasculogenic potential of dental pulp stem cells.

159 We next characterized the myogenic and vasculogenic potential of immunoselected human MPCs and

160 neage commitment of WJ-MSC and increased the vasculogenic potential of reprogrammed endothelial cells

161 a murine model, dexamethasone inhibited the vasculogenic potential of stem cells derived from human

162 Furthermore, the vasculogenic potential of these cells is under debate.

163 In vitro vasculogenic potential was assessed by quantifying EPC c

164 Herein, we analyzed whether this vasculogenic process is regulated by estrogen.

165 Coronary artery development is a complex vasculogenic process that begins shortly after heart loo

166 looxygenase (COX)-2 signaling regulates this vasculogenic process.

167 s involved in endothelial cell apoptosis and vasculogenic processes as well as immunoregulatory signa

168 tromal cell-derived factor 1/CXCR4-dependent vasculogenic progenitor cell mobilization and promotes v

169 , and receptors AT1 and Mas-are expressed in vasculogenic progenitor cells derived from humans and ro

170 eutic approach to inhibit PDGFRbeta-mediated vasculogenic properties of TNBC, focusing on miR-9 and m

171 ve demonstrated that human ECFCs have robust vasculogenic properties.

172 men with erectile dysfunction of neurogenic, vasculogenic, psychogenic, or mixed causes, respectively

173 The vasculogenic, rather than angiogenic, nature of this neo

174 rs are expressed in the lateral plate and in vasculogenic regions of the avian somite and are able to

175 n and proliferation of progenitor cells with vasculogenic/reparative potential.

176 groups also showed a significantly improved vasculogenic response in the EPCM group.

177 ontractile function, histopathology, altered vasculogenic signaling, and lower mitochondrial respirat

178 2 (Tie2) expression appears in hemogenic and vasculogenic sites shortly after SCL.

179 ment and decreased Smad1/5/8 activity in key vasculogenic structures.

180 ll RNA sequencing, identified emergence of a vasculogenic subset with a distinct fibroblast transcrip

181 tumor cells, suggesting the possibility of a vasculogenic switch.

182 genic glioma cells and spontaneously arising vasculogenic tumors in NF1+/-:Trp53+/- mice, but not by

183 lation, have an abnormal distribution within vasculogenic vessels.