ライフサイエンスコーパス: vastly

1 aw data to reduce investigator's bias and to vastly accelerate overall analysis time.

2 e demonstrate how data-driven approaches can vastly accelerate the search for complex structures, com

3 eq), followed by computational analysis, has vastly accelerated the identification of viral and other

4 o and La Nina events, but the change differs vastly across models(17), which is partially attributed

5 t disrupting the autoinhibition results in a vastly activated enzyme complex.

6 Furthermore, aging vastly alters the transcriptional profile and specifical

7 mino acid sequence of the RPT domain differs vastly among various vertebrates, we show that it is a f

8 organoids analogously to large sibships and vastly amplifying the test power.

9 Computational predictions vary vastly, and it is not clear that any significant accurat

10 of many taxa [1, 2], but the extent differs vastly between [3, 4] and within trophic levels [5-7].

11 The study of cancer metabolism has evolved vastly beyond the remit of tumour proliferation and surv

12 se enzyme kinetics with dNTP levels that can vastly change, depending on cell proliferation profiles.

13 a sample, as shown for fossils, which would vastly complicate interpretation of REE patterns.

14 t, accessible, and reliable information in a vastly connected world makes disposable sensors increasi

15 ly in the cortex, but a higher resolution is vastly dependent on sample size and statistical power.

16 a broad group of diverse DNA variants which vastly differ in their sizes and distributions across th

17 compounds was observed and was traced to the vastly different acidities of the M-H bonds and overall

18 e three catalytic sites of ATP synthase have vastly different affinities for nucleotides, and the pos

19 cific seaboards, by evolutionary clusters of vastly different ages and genomic diversity levels.

20 saic complexes composed of polypeptides with vastly different ages.

21 and breadth of the retrotranscriptome can be vastly different among cell types.

22 ensive versus minimal woody cover often have vastly different animal communities.

23 Constituent ReS2 and WS2 layers have vastly different atomic structure, crystallizing in anis

24 fferent gut bacterial lineages and did so on vastly different bacterial phylogenetic resolutions.

25 simulated incidence time series data exhibit vastly different behaviours to those previously studied

26 e patterns in changes in gene expression are vastly different between male and female rats.

27 While the methylomes were vastly different between muscle tissue and HDMCs, we ide

28 that the transcriptional targets of LMO4 are vastly different between the two brain regions, which ma

29 attachment proteins of paramyxoviruses have vastly different binding affinities for their cognate re

30 red with a consistent accuracy despite their vastly different capillary lengths if one keeps the lens

31 nes different batches of scRNA-seq data with vastly different cell population compositions and amplif

32 ifferent metal ions produces elastomers with vastly different characteristics.

33 Given the vastly different chemistries of PEG and unfolded protein

34 th similar potency and kinetics, but display vastly different clinical profiles.

35 ntial nutrients, including iron, under these vastly different conditions.

36 omain but intriguingly have to operate under vastly different conditions.

37 as depth of freshwater, radius of ENPs) show vastly different degrees of influence on the outcomes.

38 Despite the vastly different detection limits of NMR and MS, chemome

39 well as their scalable integration with two vastly different devices: classical photonic crystal cav

40 inding shares common characteristics between vastly different DNA-bound proteins and thus may have a

41 ing the topography of the element leads to a vastly different dynamic response that arises due to the

42 st pollinators recognize "flower objects" in vastly different ecologies and environments.

43 However, individual paralogs can confer vastly different effects upon cellular processes, e.g.,

44 In this work, we present a vastly different elastic solid model (ESM) of macromolec

45 vestigated leaves from 10 Ficus species from vastly different environments (Rehovot, Israel; Bologna,

46 ervasive among different lineages and across vastly different evolutionary scales, achieving predicta

47 encoding of environments and experiences of vastly different extents and durations, and could reflec

48 The molecular basis underlying the vastly different fibrillation behaviours of these TTR mu

49 ype and that oncogenic mutations should have vastly different fitness effects on somatic cells depend

50 conditions, the magnitude of cyclization is vastly different for different portions of samples from

51 ed bisphenol exhibits unique retention times vastly different from their native counterparts leading

52 disturbances, Caribbean reef communities are vastly different from those described in the 1950s.

53 To detect and respond to vastly different groups of pathogens, the innate immune

54 00 million years of independent evolution in vastly different habitats.

55 h far-field climate forcing, which separates vastly different hydroclimate regimes before and after a

56 area needs to nurture the environment where vastly different ideas can be tested, and all data, posi

57 isomeric T. cruzi growth inhibitors revealed vastly different in vitro properties such as solubility,

58 tion to identical initial conditions induces vastly different initial ENSO variability, which systema

59 - and Cu(+)-doped semiconductor NCs with the vastly different ionization potentials of their Ag(+) an

60 l components, permits its members to process vastly different kinds of food.

61 Despite this, the two derivatives show vastly different kinetic properties.

62 Each isomer has vastly different light-switching properties: mer is "on"

63 re obtained, with two dimensions acquired at vastly different magnetic fields.

64 jury, lesions of comparable size can produce vastly different magnitudes of functional impairment and

65 tautomer of the products, again resulting in vastly different materials.

66 en two materials, i.e. tendon and bone, with vastly different mechanical properties.

67 to be consistent across study locations with vastly different meteorological, geographical, and cultu

68 s and disadvantages involved in studying two vastly different organ systems.

69 at appear qualitatively similar can engender vastly different outcomes for diversity: Depending on th

70 in innate and adaptive immune cells leads to vastly different outcomes with respect to bacterial cont

71 Perceptually similar stimuli often predict vastly different outcomes, requiring the brain to mainta

72 lizing mechanical metamaterials that exhibit vastly different output displacements under excitation f

73 hexagonal manganites are highly relevant to vastly different phenomena from the birth of our cosmos

74 fferences in microbial genomes can result in vastly different phenotypes and functions.

75 Genetic ablation of NRF1 or NRF2 results in vastly different phenotypic outcomes, implying that they

76 Small-angle neutron scattering reveals vastly different polymer conformations of the multivalen

77 d through the substrate channel, albeit with vastly different potencies and with differential interac

78 e sequences are very similar, despite having vastly different propensities for single-stranded helica

79 n lead to a range of hydrogel materials with vastly different properties, starting from a set of simp

80 ns with the same total baseline area grew at vastly different rates, with an estimated ratio of the g

81 show that N- and C-terminal cassettes adopt vastly different relative orientations in a crystal stru

82 around different "frameworks" typically have vastly different responses; second, the distribution of

83 BCs) are stem cells, but the two types plays vastly different roles.

84 resorting components, (ii) toggling between vastly different rotational exchange rates in the self-a

85 ary mechanism for creating new proteins with vastly different sequences, yet similar physicochemical

86 ution must therefore be tuned for genomes of vastly different sizes.

87 to efficiently fabricate these materials at vastly different sizes.

88 the brains of humans and animals can exhibit vastly different spatial patterns when faced with differ

89 These nickelacycles show a vastly different stability in solutions.

90 en a formidable challenge, mainly due to the vastly different standard reduction potentials of the tw

91 h of the four stereoisomers in 20 samples of vastly different stereoisomeric compositions with an ave

92 By using a competing-risk model, vastly different surveillance durations were appreciated

93 on of charge carriers - effects operating at vastly different time domains.

94 pendent perspectives on plastid formation on vastly different timescales.

95 How do signals integrate to make such vastly different tissues and organs given that the seque

96 uence isoforms of the same miRNA can possess vastly different turnover rates.

97 and it is generally expected for waves with vastly different wavelengths, for example, branched flow

98 TE activation in two Drosophila species with vastly different Y chromosomes of different ages.

99 s, and lipids), and downstream functions are vastly different, depending on the cell origin.

100 ced economic choices, even when rewards were vastly different, such as liquid and food.

101 ) are recently diverged species that inhabit vastly differing habitats.

102 Prior HFD consumption vastly diminished the capacity of SD to alleviate the ne

103 We found that although TP53 elicits vastly divergent signaling cascades across cell lines, i

104 ng a single direction, consistent across the vastly diverse biological conditions and coinciding with

105 lanation why cancer cell lines known to have vastly diverse expression levels of Wip1 and PTEN exhibi

106 computational work on gene fusions has been vastly diverse, and the present state of the literature

107 treatment with HKL ablated this response and vastly enhanced the rate of apoptosis.

108 bled representation of space and time, which vastly enhances this process.

109 owerful biological engineering applications, vastly enhancing the scope and efficiencies of genetic e

110 blood, we hypothesized that lymph should be vastly enriched in cancer biomarkers.

111 ion, our understanding of ubiquitin (Ub) has vastly evolved.

112 of tobacco smoking by people living with HIV vastly exceed that of the general population.

113 ntial to integrate processing functions that vastly exceed the capabilities of electronics.

114 owledge and useful clinical information-will vastly exceed the capacity of even the largest instituti

115 hat contact line velocities atop the pillars vastly exceed those associated with viscoelastic braking

116 Nine variants vastly exceeded the potency of their parental antibodies

117 odium contained within the dry MN alone, was vastly exceeded, indicating extensive delivery of the dr

118 converted to the desired compounds on scales vastly exceeding those achievable by HPLC.

119 The extent of regulation within females vastly exceeds sex differences, and supports a multi-lev

120 least in metazoans, the observed repression vastly exceeds that typically observed for endogenous mR

121 ns (~6-fold vs. uncoated C. albicans), which vastly exceeds the forces between S. gordonii andC.

122 bitats experience annual pH variability that vastly exceeds the magnitude of long-term projections in

123 In most taxa, the number of DSBs vastly exceeds the number of COs.

124 ry genes (e.g., transcription factors (TFs)) vastly exceeds the number of experimentally-verified reg

125 red to build, model or analyse the community vastly exceeds what is feasible using current methods.

126 to the ECM and provide a resource that could vastly expand our understanding of controls involving "o

127 These interaction networks will vastly expand the functional annotation of the kinetopla

128 h entropy alloy (HEA) development strategies vastly expand the number of candidate alloy systems, but

129 these materials engineering principles will vastly expand the optical engineering landscape of fluor

130 r outflow tract [RVOT]) has the potential to vastly expand the population of patients eligible to ben

131 signals are combined in unexpected ways that vastly expand the possible representations of the outsid

132 into proteins in a site specific manner can vastly expand the repertoire of protein functions and al

133 -carrying capacity of a single photon can be vastly expanded by exploiting its multiple degrees of fr

134 Since then, however, CTD has vastly expanded its scope to robustly represent a triad

135 espite the passage of more than 50 years and vastly expanded neuroscience tool kits remain applicable

136 tagenomic sequencing and bioinformatics have vastly expanded our knowledge of microbial phylogenetic

137 ces in C-H functionalization technology have vastly expanded our toolbox for organic synthesis(1).

138 -scale transcriptome sequencing efforts have vastly expanded the catalog of long non-coding RNAs (lnc

139 New metagenomic studies vastly expanded the crAss-like phage group and demonstra

140 tures across the different forms of CLRP has vastly expanded the range of functional materials access

141 Humans have vastly expanded the spatial and seasonal "fire niche" in

142 ate but also addressing controversies in the vastly expanding halide perovskite literature.

143 0 000 microbial genomes without any culture, vastly expanding our knowledge of the biases in existing

144 al neurons flexibly join multiple ensembles, vastly expanding the encoding potential of the circuit.

145 rint provides the fundamental principles for vastly expanding the use of abundant metals in catalysis

146 ight ratio of the overall structure 17-fold, vastly expanding their potential application.

147 output of over 200 molecular measures would vastly extend the relevance of the sample collections an

148 y rather than volatility of precursors which vastly extends the range of potentially applicable compo

149 entiating NETotic from non-NETotic cells and vastly facilitated dose-response analysis and screening

150 However, eukaryotic genomes exhibit vastly greater complexity, which raises questions not ad

151 igh-density microarray studies have revealed vastly greater herpesvirus transcriptome complexity than

152 ng the question of how they can modulate the vastly greater output of the power muscles during manoeu

153 Vastly greater quantities of microbial genome data are b

154 MWCNTs oxidized with nitric acid exhibited vastly greater rates of ozone consumption and *OH format

155 However, triple-negative disease is vastly heterogeneous, encompassing multiple entities wit

156 Autism (ASD) is vastly heterogeneous, particularly in early language dev

157 artificially designed solid-state systems at vastly higher temperatures than achievable in optical la

158 dulin (CaM) acts in KRAS-driven cancers is a vastly important question.

159 Call to map cancer proliferation pathways is vastly important since it can expedite effective therape

160 ddresses a key issue in telehealth that will vastly improve its capabilities and adoption worldwide.

161 plification (RCA)-based target enrichment to vastly improve NGS-based rare variant detection.

162 phic mechanisms through which they act, will vastly improve our ability to predict species responses

163 f they can be replicated, such studies would vastly improve our understanding of pathogenic processes

164 understanding the associated processes could vastly improve quality of life.

165 dation of more-reactive diazoalkane species, vastly improve the accessibility and utility of this der

166 optimistic that the big-data revolution will vastly improve the granularity and timeliness of availab

167 nds of evolution, we developed variants with vastly improved activity toward some of the linkages tha

168 A fiber-elastomer composite design with a vastly improved and directional actuation response is pr

169 Overall, we demonstrate a vastly improved approach to analyzing ddPCR data that ca

170 al stability of black CsPbI(3) thin films is vastly improved by the strained interface, a response ve

171 (SAR) leading to the discovery of 4 that is vastly improved from the first generation late INa inhib

172 once limited, treatment of this disease has vastly improved in the last decade.

173 cides, sanitizers, and detection methods has vastly improved knowledge of this new invasive disease i

174 ved, clear potential exists for developing a vastly improved mechanistic understanding of animal move

175 of the anti-inflammatory cytokine IL-10, and vastly improved mouse survival.

176 Advances in molecular genetics have vastly improved our understanding of the biological dive

177 Long-term simvastatin treatment vastly improved overall muscle health in mdx mice, reduc

178 In particular, due to its vastly improved photostability compared to that of conve

179 pled peptides based on RLIP76 that exhibited vastly improved selectivity for Ral GTPases when compare

180 entarity in dovetailing these techniques for vastly improved single-molecule sensing.

181 d interaction: flexible transition rules and vastly improved spatial addressability of the quantum sy

182 Furthermore, the rerouted FSH vastly improved the in vivo fertilization competency of

183 ments in modelling power and input data have vastly improved the precision of physical flood models,

184 on, by employing multi-threading, rMAPS2 has vastly improved the user experience with significant red

185 cifically materials' functionalities, can be vastly improved through physical insights and careful da

186 ith our first-generation catalyst, providing vastly improved yields of allylsilanes from simple alken

187 tion or the hybrid procedure, survivals have vastly improved, and large numbers of these patients are

188 Results showed that WGS vastly improves our ability to delimit the scope and sou

189 ing from the same unit over time, the HFS-TB vastly improves statistical power and facilitates the ex

190 t a digital electronic add-on technique that vastly improves the dynamic range of a multiphoton micro

191 Moreover, mammalian cortices differ vastly in size, cytological composition, and phylogeneti

192 fling" of antigen-encoding gene sequences to vastly increase antigen diversity and to enable copy num

193 nt achieved by these metallic nanostructures vastly increase spectroscopic sensitivity, enabling real

194 As technological innovations vastly increase the amount of data we collect, the impor

195 These sources vastly increase the availability of peptides for present

196 s possible for short peptide macrocycles and vastly increase the available starting scaffolds for bot

197 innovative capabilities offer a platform to vastly increase the number of biologically detectable mo

198 trates how proton donor/acceptor ligands can vastly increase the range of accessible states in switch

199 rovided more definitive information but also vastly increased amounts of data.

200 Modern agricultural practices have vastly increased crop production but negatively affected

201 Furthermore, nonsurvivors exhibited a vastly increased hypermetabolic response that was associ

202 evolution of intravital microscopy (IVM) has vastly increased our ability to directly visualize immun

203 eceptor potential (TRP) channel research has vastly increased our understanding of the physiological

204 cytometry enables simultaneous assessment of vastly increased phenotypic parameters at single-cell re

205 s and estimation of underlying TADs across a vastly increased range of Metazoan genomes.

206 es in high-resolution mass spectrometry (MS) vastly increased the number of samples that can be proce

207 and recent genome editing technologies have vastly increased the power of reverse genetics but selec

208 ojection patterns of individual neurons with vastly increased throughput.

209 This process of genetic exchange vastly increases the diversity of circulating influenza

210 increasing frequency, yet their very number vastly increases the scope of possible GEI, making it di

211 mic, lipidomic, and metabolomic analyses are vastly increasing in popularity.

212 rs (XFELs) can outrun most damage processes, vastly increasing the tolerable dose before the specimen

213 t the approach we described in our report is vastly inferior in efficiency to alternative off-the-she

214 y of monoclonal stalk-binding antibodies was vastly inferior in vitro but was enhanced by several ord

215 ontent, even though postprandial glycemia is vastly influenced by glycemic index (GI).

216 in supporting beta-cell homeostasis has been vastly investigated, the role of pericytes remains large

217 lection in the thymus is able to recognize a vastly larger antigenic pool.

218 ct interactions, facilitating exploration of vastly larger GI manifolds.

219 ave interfacial attachment energies that are vastly larger than the thermal energy, hence they are us

220 molecules known to be active or inactive is vastly less than the number of possible chemical feature

221 This results in vastly longer excess carrier lifetimes (up to ~50 ms), w

222 This mechanism requires vastly lower energy inputs and demonstrates an alternati

223 lectivity for Cx-SAM as alkyl donor over the vastly more abundant SAM.

224 n about health risks from chemical exposures vastly more accessible, it could ultimately enable compu

225 ical evolvability that are not accessible in vastly more complex natural systems.

226 te their simplicity, capture key features of vastly more complicated turbulent systems.

227 rnalization facilitated a broader shift to a vastly more cooperative form of social life by establish

228 The construction of molecules would be vastly more efficient if carbon-hydrogen bonds, found in

229 Photovoltaic-based power will always be vastly more efficient than a terrestrial crop biofuel.

230 lculates the prime factors of a large number vastly more efficiently than a classical computer.

231 ination can potentially provide viruses with vastly more evolutionary options than are available thro

232 t they are highly brittle and that they need vastly more examples than do people.

233 obile small-molecular cargo, which can reach vastly more immune cells throughout the lymph node than

234 nic library construction methods often yield vastly more nonfunctional than functional variants and,

235 ed at a higher temperature than PLA, emitted vastly more particles and their composition differed fro

236 correlations; (2) Neural circuit function is vastly more sensitive to changes in some cellular compon

237 Yet, bacteria are vastly more taxonomically diverse, numerically abundant,

238 Although previously reported, vastly optimized yields with respect to deuteroporphyrin

239 the genes found by pairwise resampling (and vastly out-performs ANOVA), but it also identifies addit

240 ract is home to trillions of bacteria, which vastly outnumber host cells in the body.

241 saturation up to 60 T, although the vortices vastly outnumber pinning centers.

242 tory bulb (OB), diverse interneuron subtypes vastly outnumber principal excitatory cells.

243 re balanced, ammonia-oxidizing archaea (AOA) vastly outnumber the main nitrite oxidizers, the bacteri

244 Natural nonproteinogenic amino acids vastly outnumber the well-known 22 proteinogenic amino a

245 Second, stem cells are vastly outnumbered by differentiated cells, which have a

246 The number of applicants vastly outnumbers the available academic faculty positio

247 ls and whole organisms with new applications vastly outpacing detection and quantification of gene-ed

248 monstrate that low-charge macromolecules can vastly outperform their acidic counterparts in the synth

249 o enhances T-cell potency, with edited cells vastly outperforming conventionally generated CAR T cell

250 ses, the classifier achieved 96.8% accuracy, vastly outperforming the SVM.

251 samples from 44 datasets shows that PINSPlus vastly outperforms other approaches.

252 solutions (which are typically ignored) can vastly outweigh that of the supported efficient solution

253 conclusion that their therapeutic potential vastly outweighs the challenges in their design.

254 suggests that a sole focus on plaque rupture vastly oversimplifies this complex collection of disease

255 Zinc is vastly present in the mammalian brain and controls funct

256 To address the unmet need for vastly prolonged E2 release, we report first-generation

257 protofilament in which the molecules adopt a vastly rearranged, lower energy fold compared to wild-ty

258 which take advantage of higher symmetries to vastly reduce the dispersion.

259 al-comb Vernier frequency division method to vastly reduce the required electrical bandwidth.

260 lly, HBOC-201 and blood-perfused kidneys had vastly reduced acute tubular necrosis scores and degrees

261 hically-fabricated gold electrodes, but at a vastly reduced cost (>50 times lower per array).

262 We found a vastly reduced expression of NR4A1 and NR4A3 in chronic

263 gradation also in the Antarctic, albeit at a vastly reduced rate compared to warmer environments.

264 Compared with WT PV1, P2(Min) displayed a vastly reduced specific infectivity (si) (WT, 1 PFU/118

265 This burden could be vastly reduced with new funding to scale up cost-effecti

266 following tail-vein injection into mice was vastly reduced.

267 r, minimal two-component RD descriptions are vastly simpler than the multi-molecular events that actu

268 assembly or specialized bacteria, therefore vastly simplifying cloning procedures.

269 ortantly, we found that BBB permeability was vastly spared in mouse models of AD, including PS2-APP,

270 In contrast to vastly studied hypocotyl growth, little is known about d

271 rformance and reaction time variability, two vastly studied indicators of attention.

272 The model was vastly superior for long-term prognosis as well, outperf

273 New World CL, 15% paromomycin-aquaphilic was vastly superior to a negative vehicle control and was co

274 d retained a proliferative capacity that was vastly superior to TEFF.

275 nal reductionist approaches have contributed vastly to our knowledge of biological systems in health

276 nding affinities but optimal syntax may be a vastly underappreciated feature of the regulatory genome

277 demonstrates that current genome assemblies vastly underestimate the complexity, abundance, and vari

278 Liver diseases represent a vastly underestimated and historically neglected public

279 the inner follicular surface, and therefore vastly underestimated the potential of the skin microbio

280 sms and their derivations have probably been vastly underestimated.

281 Neglecting interactions between stressors vastly underestimates the risk of population crashes.

282 The atmosphere is vastly underexplored as a habitable ecosystem for microb

283 d to direct inhibition, PPI stabilization is vastly underexplored but has strong advantages, includin

284 aryotic microbial diversity of mosquitoes is vastly underexplored.

285 he majority of studies in the Vannucci model vastly underpowered to detect true treatment effects due

286 This motif is vastly underrepresented in H. pylori genomes, but overre

287 e argue that bleaching in the Red Sea may be vastly underrepresented.

288 erformed by using a 4D radial phase-contrast vastly undersampled isotropic projection reconstruction

289 Fungi are vastly understudied in the marine realm and knowledge of

290 ects of the protective APOE2 gene allele are vastly understudied, and thus need to be further clarifi

291 sms coordinating biliary regeneration remain vastly understudied.

292 aser resurfacing, represents a promising and vastly underused tool in the multidisciplinary treatment

293 he secondary prevention of ASCVD, it remains vastly underutilized due to significant barriers.

294 This vastly unexplored ecosystem is believed to be mostly sus

295 c potential of selective mGlu1 activation is vastly unexplored relative to the other group I mGlu rec

296 V) as mediators of these interactions remain vastly unexplored.

297 he genetic susceptibility to UM is currently vastly unexplored.

298 n-Pick Type C2 (NPC2) sterol transporter are vastly up-regulated in symbiotic cnidarians.

299 Vastly used analytical methods have so far struggled to

300 IRS) haemodynamic measures have proven to be vastly useful in investigating human brain development,