ライフサイエンスコーパス: vector

1 required to keep the intensity of the aroma vector.

2 e brain of APP/PS1 mice treated with miRCD33 vector.

3 t (mut) were delivered by an adenovirus (Ad) vector.

4 enous injection of an integrating HDAd5/35++ vector.

5 re the potential of AAVv66 as a gene therapy vector.

6 sis population to act as an arbovirus bridge vector.

7 analysis of S-F progression with a combined vector.

8 betaherpesvirus (DrBHV) to act as a vaccine vector.

9 ed this technology to adeno-associated viral vectors.

10 may enhance genetic connectivity of malaria vectors.

11 g distributional shifts of pests and disease vectors.

12 r:BvLz lines with additional BvLz expression vectors.

13 onal expansion of cells harboring integrated vectors.

14 y, whilst reducing the cost of preparing the vectors.

15 estore pyrethroid susceptibility in mosquito vectors.

16 that healthcare workers could act as silent vectors.

17 a critical role in public health as disease vectors.

18 uman body using adeno-associated virus (AAV) vectors.

19 ference frame, yielding 3-dimensional motion vectors.

20 ammalian host's blood and in transmission to vectors.

21 vg per animal, n = 10 per group) with PHP.B vectors.

22 f Pd nanoparticles to create new therapeutic vectors.

23 their properties as AAV/HBoV1 gene transfer vectors.

24 thereby raising the discovery cost of novel vectors.

25 e tendency for parasites to take up multiple vectors.

26 magnetofection technology and minicircle DNA vectors- a promising cell engineering approach we previo

27 We found that the vector addition models captured the tendency of particip

28 figural-based computational models involving vector addition, the second of which included terms for

29 tegies to manage wild populations of disease vectors, agricultural pests, and invasive species.

30 ared to vaccination with each single-antigen vector alone.

31 the near elimination of the primary malaria vector An. funestus and a corresponding reduction of mal

32 ed adenovirus type 5 host range mutant empty vector and alum.

33 The resultant vector and its confidence interval were plotted in 2-dim

34 e malaria parasite infection in the mosquito vector and provide new insight into the mechanisms of ha

35 are located in the backbone of the phagemid vector and the library insert comprises only the variabl

36 blood cells transduced with a lentiviral MYC vector and then transplanted into immunodeficient mice p

37 e expression as it transits between its tick vector and vertebrate host.

38 luding large-scale variability in pathogens, vectors and associated diseases.

39 mission by limiting contact between mosquito vectors and human hosts when mosquitoes feed during the

40 actions between calibration model regression vectors and new sample spectra allowing fully matrix mat

41 d for the selection of insecticide-resistant vectors and the spread of resistance through repeated de

42 of comparative data regarding both emerging vectors and their pathogens.

43 heteroplasmy, exogenous DNA sources such as vectors, and epigenetic changes such as imprinting and X

44 of pairwise dissimilarities between pattern vectors, and model cortical topography as mixtures of ov

45 n and alignment perpendicular to the stretch vector are dependent on formin-regulated actin polymeriz

46 ncer (much like other pathologies), delivery vectors are designed to exploit physical and biological

47 ure selection and (iii) the obtained feature vectors are fed into XGBoost to predict protein submitoc

48 In these interventions, targeting vectors are labelled with alpha-emitting radioisotopes t

49 virus infection will improve the use of this vector as a tool for gene therapy.

50 Astigmatism as calculated by vector astigmatism analysis stayed stable at 1 month, 3

51 a suggests that to design a potentially safe vector-based pan-Leishmania vaccine, without geographic

52 ated virus (AAV) is a promising gene therapy vector because of its efficient gene delivery and relati

53 eved a sensitivity of - 1.4 nm/ degrees as a vector bending sensor and - 17.5 nm/m(-1) as a curvature

54 idemic LB now constitutes the most important vector borne disease in the United States.

55 Lyme disease is the most common vector-borne disease in temperate zones and a growing pu

56 Lyme disease is the most common vector-borne disease in the northern hemisphere and is c

57 panosomiasis ([gHAT] sleeping sickness) is a vector-borne disease that is typically fatal without tre

58 answered questions in the realm of bacterial vector-borne disease, focusing on liberibacters, phytopl

59 omic, behavioral, and institutional factors, vector-borne diseases are complex 'wicked problems'.

60 the context of the prevention and control of vector-borne diseases has been broadly described in both

61 endectocide, which reduces the incidence of vector-borne diseases.

62 The prevention of vector-borne illnesses, the determination of the mosquit

63 Zoonotic and vector-borne parasites are important preventable risk fa

64 e ZIKV immunity.IMPORTANCE ZIKV emerged as a vector-borne pathogen capable of causing illness in infe

65 ment of genetic technologies for controlling vector-borne pathogen transmission.

66 rsity-disease relationships and suggest that vector-borne, generalist wildlife and zoonotic pathogens

67 friendly web interface and many more plasmid vectors, but also new links of the plasmids to advanced

68 the thermally-stable antiferromagnetic Neel vector by spin-orbit torques.

69 t evidence that gene therapy mediated by AAV vectors can be used for treating CDKL5 disorder.

70 and exosome-associated preparations of AAV8 vectors can effectively transduce a variety of immune ce

71 and treated them with neurotrophic AAV-PHP.B vector carrying the mouse Slc25a46 coding sequence.

72 payload (i.e., doxorubicin), these cellular vectors (CELVEC) were shown to provide continued release

73 Safety, efficacy, predictability, astigmatic vector changes, contrast sensitivity, endothelial cell c

74 healthy volunteers vaccinated with a measles-vectored chikungunya vaccine candidate, MV-CHIK, were an

75 ne against RSV (ChAd155-RSV) using the viral vector chimpanzee-adenovirus-155, encoding RSV fusion (F

76 Modelling involves identifying typhoon track vectors, clustering vectors using a self-organizing map,

77 o rapidly produce fully synthetic MVA (sMVA) vectors co-expressing SARS-CoV-2 spike and nucleocapsid

78 Vector competence and the extrinsic incubation period (E

79 The relatively modest vector competence for DENV and YFV, combined with a lack

80 idemics such as ZIKV despite relatively poor vector competence in single-feed laboratory trials.

81 When single-stranded vectors contained an S (p)-Me-PTE in the sequence contex

82 young wine model, V1 could be replaced by a vector containing just 3 odorants (ethyl 2-methylbutyrat

83 In the oaky model, a vector containing just ethyl 2-methylbutyrate (V7) could

84 We designed mAGNET viral vectors containing a CaMKIIalpha promoter and microRNA-1

85 tors from pGWBs series to produce expression vectors containing the stevia's UGT, enables functionali

86 Surprisingly, in a recombinant vector context, T590S was beneficial and significantly i

87 ug administration (rfMDA) and reactive focal vector control (RAVC) in the low malaria-endemic setting

88 ication of phytosanitary measures, including vector control and inoculum suppression, by removing hos

89 l Guard has the potential to improve malaria vector control and provide better community protection a

90 nt for International Development, Innovative Vector Control Consortium, and Bill and Melinda Gates Fo

91 d LLINs and support the urgent deployment of vector control interventions incorporating PBO, chlorfen

92 ited antiviral drugs and vaccines available, vector control is the primary approach to prevent mosqui

93 Malaria vector control may be compromised by resistance to insec

94 Thus, a novel method of vector control may involve targeting sugar-feeding mosqu

95 rioides in comparison to wild type and empty-vector control plants.

96 are a useful guide in the development of new vector control products, and that the Complex I inhibito

97 tor that go on to form the basis of national vector control programs or more broadly support local he

98 ools that can be deployed alongside existing vector control strategies is key to eradicating malaria

99 ere gene drives act in concert with existing vector control tools such as ITNs.

100 for the potential epidemiological impacts of vector control.

101 expression by coexpressing it with the ALVAC vector could increase the protective immune responses.

102 ic CD8(+) T cell responses elicited by viral-vectored CSP-expressing vaccines effectively targeted pa

103 y polarized spatial fibre modes, cylindrical vector (CV) beams and helical phase front optical vortex

104 Intratracheal administration of this vector delivering murine or human proSFTPB cDNA into SP-

105 ion of miR-1 was achieved through lentiviral vector delivery or induction of a transgene.

106 procedures is unique and has led to improved vector delivery.

107 ts for malaria incidence, as well as malaria vector density and associated sporozoite prevalence.

108 These column vectors describe the effects each species has on all oth

109 We show that mice immunized with these sMVA vectors develop robust SARS-CoV-2 antigen-specific humor

110 at reduce the effective depth of synthesized vector DNA libraries, thereby raising the discovery cost

111 ccine candidate chimpanzee adenovirus type 3-vectored Ebola Zaire vaccine (ChAd3-EBO-Z) and boosted w

112 The adeno-associated virus (AAV) vector effectively transduced in the cerebrum, cerebellu

113 etinal delivery of an adeno-associated viral vector encoding codon-optimized human RPGR (AAV8-coRPGR)

114 A ChAdOx1 vector encoding structural antigens (ChAd-S) was also co

115 reF, a replication-incompetent adenovirus 26 vector encoding the F protein stabilized in prefusion co

116 is modified by the integration of lentiviral vectors encoding CAR that direct tumor cell killing.

117 was enhanced by co-treatment with adenoviral vectors encoding SOX17.

118 Oncolytic vectors engineered to express checkpoint blockade antibo

119 Vector engineering can increase AAV transduction efficie

120 Host relatedness and traits known to promote vector exposure neither predicted infection probability

121 The vector-expressed F protein had been engineered (DS-Cav1

122 NK cells were transduced with a retroviral vector expressing genes that encode anti-CD19 CAR, inter

123 oost with RSV or a parainfluenza virus (PIV) vector expressing RSV fusion protein engineered for enha

124 rencephalic brain of larger mammals, a hu.32 vector expressing the green fluorescent protein reporter

125 strain 68-1 rhesus macaque (RM) CMV vaccine vectors expressing HBV Ags engender HBV-specific CD8(+)

126 Based on these promising data, dual-antigen vectors expressing PfLSA1 and PfLSAP2 will now proceed t

127 ion with a combination of the single-antigen vectors expressing PfLSA1 or PfLSAP2 was shown to improv

128 ng lymphocytic choriomeningitis virus (LCMV) vectors expressing the human cytomegalovirus antigens gl

129 ted, but the current work suggests that high vector expression will not produce an excess of the norm

130 -borne, tick-borne, insect-only, and unknown-vector flavivirus groups.

131 ly it to Aedes aegypti, an invasive mosquito vector for arboviruses (e.g. dengue, zika and yellow fev

132 Adeno-associated virus (AAV) is a promising vector for gene therapy, but its broad tropism can be de

133 cus on the sea surface microlayer (SML) as a vector for microplastics, and use SML sampling to assess

134 variety of bacteria received and carried the vector for over 60 days after inoculation.

135 ows the important role of krill exuviae as a vector for POC flux.

136 eplicating Epstein-Barr virus-based episomal vector for the long-term encoding of ncAAs in human hema

137 se as a live-attenuated vaccine or a vaccine vector for the treatment of mammarenavirus and/or other

138 se as a live-attenuated vaccine or a vaccine vector for the treatment of other viral infections.

139 encing (VIGS) or synthetic transacting siRNA vectors for gene silencing.

140 The use of non-viral vectors for in vivo gene therapy could drastically incre

141 quality through viral uptake or may serve as vectors for infection by accumulating viruses.

142 e effective anterograde trans-synaptic viral vectors for neural circuit analysis in multiple species.

143 ncerns over the role of reusable plastics as vectors for SARS-CoV-2 virus contributed to the reversal

144 Plant viruses rely on insect vectors for transmission among plant hosts, but many of

145 development of poxviruses as gene expression vectors for use as recombinant vaccines.

146 ine neurons precisely represents the impulse vector (force exerted over time) generated by the animal

147 stem to efficiently generate recombinant MVA vectors from chemically synthesized DNA.

148 ealed indigenous bacteria could obtain these vectors from E. coli through several mechanisms of horiz

149 The combined use of binary vectors from pGWBs series to produce expression vectors

150 llowing the accurate determination of motion vectors from the PET data itself.

151 participants (one who had received 6x10(12) vector genomes [vg] per kilogram of body weight and one

152 The mouse, rat, and human brain flatmap vector graphics files (Adobe Reader/Acrobat viewable and

153 ces selected tick proteins that modulate the vector gut microbiota towards an environment that favour

154 cted a longitudinal investigation of malaria vector host choice over 3 years and resting behaviour ov

155 virus emergence not solely through increased vector-host contact but also as a result of enhanced vec

156 After a unilateral injection of vector, human alpha-synuclein was detected in the striat

157 However, pre-existing vector immunity and a pro-inflammatory vaccine adjuvant

158 ation as live-attenuated vaccines or vaccine vectors.IMPORTANCE To date, no Food and Drug Administrat

159 la adenovirus (GAd; GC46) as a gene transfer vector in mice.

160 Gene therapy with AAV5-hFVIII-SQ vector in participants with hemophilia A resulted in sus

161 midine-based inhibitors was developed with a vector in the 2-position that was optimized by structure

162 (Ixodes pacificus), the primary Lyme disease vector in western North America, to projected climate an

163 te and verbenone to two putative laurel wilt vectors in avocado, Xyleborus volvulus (Fabricius) and X

164 cient knowledge on the spirochetes and their vectors in the region are discussed.

165 a, based on AAV2 and AAV9, respectively, the vectors in this study will likely gain U.S. Food and Dru

166 The present model is the first lentiviral vector induced pig model of high-grade spinal cord gliom

167 Compared with RSV, boosts with the vectors induced 7- to 15-fold higher titers of RSV-speci

168 Lentiviral vector-induced re-expression of the beta4 subunit into e

169 of AMPKalpha1 by using nano-sized polymeric vector induces a favorable therapeutic effect, especiall

170 ells that were transfected with a lentiviral vector inducing constant expression of CD28 accelerated

171 IdeS treatment before AAV vector infusion was safe and resulted in enhanced liver

172 We recently reported that vector integration within the host TET2 gene was associa

173 nt hosts, but many of the specifics of virus-vector interactions are not fully understood.

174 Intrathymic injection of an AAV8-ZAP-70 vector into ZAP-70(-/-) mice resulted in a rapid thymocy

175 s Met40, Tyr68, and Asp141 to the transition vector is extremely small.

176 To address this, a neighbourhood vector is first specified for each node.

177 Four independent support vector machine (SVM) models performed to ensure the BDNF

178 DecRiPPter combines a Support Vector Machine (SVM) that identifies candidate RiPP prec

179 g from random forest (RF), nonlinear support vector machine (SVM), and deep neural network (DNN) lear

180 related hardness categories using a support vector machine algorithm.

181 ication is performed using nonlinear support vector machine and kernel Fisher discriminant analysis.

182 The Support Vector Machine Classification was applied to identify in

183 or greater accuracy than IL17A in a support vector machine classifier of psoriasis and healthy trans

184 Support vector machine decoding of alpha power patterns revealed

185 strate the method, random forest and support vector machine models were trained on within-participant

186 dom forest (0.782), XGBoost (0.781), support vector machine with linear kernel (0.780), and [Formula:

187 ed with XGBoost, k-nearest neighbor, support vector machine, random forest, logistic regression and N

188 sites and methylation types using a support vector machine-based network.

189 r voxel-wise approach using a linear support vector machine: 0.88) and similar sensitivity for identi

190 Gapped k-mer kernels with support vector machines (gkm-SVMs) have achieved strong predicti

191 Support vector machines (SVM) models can be successfully applied

192 atic Discriminant Analysis (QDA) and Support Vector Machines (SVM), analyzed in the biofingerprint re

193 forests (RFs), elastic net (ELNET), support vector machines (SVMs) and boosted trees in combination

194 ing neural networks, random forests, support vector machines and boosting, on 10 September 2019.

195 istic regression, random forest, and support vector machines were used as candidate methods to develo

196 This accuracy exceeded that of support vector machines, traditional linear discriminant, and k-

197 ics of onion yellows (OY) phytoplasma in its vector Macrosteles striifrons were investigated by immun

198 ring cell isolation, and different levels of vector marking in the various lineages.

199 ssing, manipulating and operating on data in vectors, matrices and higher-dimensional arrays.

200 conditional knockout mouse models and viral vector-mediated autophagy-modulating strategies in vivo

201 in mouse and by adeno-associated viral (AAV) vector-mediated gene augmentation of ERdj5 in P23H-3 rat

202 el for studying adeno-associated virus (AAV) vector-mediated gene therapies.

203 Furthermore, viral vector-mediated overexpression of miR-124 in the irradia

204 exposure did not induce significant delayed vector mortality 72 hours later.

205 tiparasite effector molecules to the malaria vector mosquito, Anopheles gambiae The drive system targ

206 omes modulate the capacity of insect disease vectors (mosquitoes, tsetse flies, sandflies) to transmi

207 ed with modified vaccinia Ankara Ebola Zaire-vectored (MVA-EBO-Z) vaccine.

208 Lack of vector-neutralizing Ab responses should facilitate boost

209 longipalpis sand flies are the major natural vector of Leishmania infantum parasites, responsible for

210 tes from Lutzomyia longipalpis, the sand fly vector of leishmaniasis, immunize individuals with L. lo

211 vary glycoproteins of Lutzomyia longipalpis, vector of visceral leishmaniasis in the Americas.

212 Extracellular vesicles (EVs) are important vectors of paracrine signaling implicated in a range of

213 Nyssomyia neivai is one of the main vectors of tegumentary leishmaniasis (TL) in Brazil.

214 munity's feasibility domain using the column vectors of the corresponding interaction matrix.

215 s its strong insecticidal effect on mosquito vectors of the disease, ivermectin inhibits Plasmodium f

216 Adult aquatic insects can be important vectors of waterborne contaminants to riparian food webs

217 y (SAP) and eye tracking perimetry (saccadic vector optokinetic perimetry, SVOP) was performed.

218 ectopic expression of a PKCalpha expression vector or an active Src.

219 idity, by subtly altering certain side chain vectors, or by adjusting the global shape of the macrocy

220 that human-biting in this important disease vector originally evolved as a by-product of breeding in

221 ic recombinant adeno-associated virus (rAAV) vector overexpressing the chondrogenic sox9 transcriptio

222 s phenomenon may be common among other virus-vector pairings and that A. albopictus might be a more i

223 o-imidazoquinazoline with a propyn-1-yl exit vector pointing into the transient pocket and displacing

224 compromised by resistance to insecticides in vector populations.

225 However, each viral vector possesses its own advantages and disadvantages fo

226 nstrated that mosquito populations and their vector potential are dependent upon the availability of

227 ext to the gold-standard iodixanol-based AAV vector production, we recently published a protocol for

228 The AdRGD-PG-hIFNbeta vector provides extensive killing of human melanoma cell

229 g the Streptomyces site-specific integration vector pSET152.

230 polluted sediments with E. coli carrying the vector pSF-OXB15-p450camfusion showed that the E. coli c

231 d liver transduction, even in the setting of vector readministration.

232 l connectivity, and trained a linear support vector regression model to estimate verbal memory perfor

233 glomerular responses using nonlinear Support-Vector Regression. We also discovered several previously

234 ept embeddings-which involve the learning of vector representations of concepts using machine learnin

235 We begin by learning vector representations of tasks.

236 bitat characteristics that are important for vector reproduction are imperative to understand and pre

237 Boosting instead with the rB/HPIV3-RSV-pre-F vectors resulted in efficient replication and induced si

238 enhancing the thermal tolerance of its aphid vector Rhopalosiphum padi (by 8 degrees C).

239 that contained a fragment of the integrated vector sequence and the neighboring genome sequence.

240 Our vector series, pGTag (plasmids for Gene Tagging), contai

241 injection of certain adeno-associated virus vector serotypes can cross the blood-brain barrier to de

242 Sabethes chloropterus, two known flavivirus vectors, showed significant stratification, occurring mo

243 57 dB, and -11.51 dB, respectively, and mean vector slopes for each severity categories were 0.79, 0.

244 ns with common geometric structure provide a vector space that codes inferred item relationships with

245 ability for, and geographic distribution of, vector species under projected climate change scenarios.

246 Our findings support the development of BCG-vectored STING agonists as a tuberculosis vaccine strate

247 Temporal coding quality was evaluated as vector strength in response to tones at best frequency,

248 tance imposes a high fitness cost in malaria vectors supporting that a resistance management strategy

249 ost contact but also as a result of enhanced vector susceptibility.

250 that A. albopictus might be a more important vector than once thought.

251 inferred item relationships with a direction vector that is consistent across triads, thus supporting

252 Ankara (MVA) is a highly attenuated poxvirus vector that is widely used to develop vaccines for infec

253 es (Macaca mulatta) were immunized with Ad26 vectors that encoded S variants or sham control, and the

254 lencing efficacy of gene targets, we created vectors that facilitate insertion of any gene target seq

255 on to efficiently generate sparse projection vectors that improve the chemical interpretability of th

256 the two most significant genera of arbovirus vectors that infect people, were tested.

257 read by travelers and adapts to new mosquito vectors that live in temperate climates.

258 iviral (LV) and adeno-associated viral (AAV) vectors that preferentially express anti-sense miR again

259 e the biology and behaviour of many mosquito vectors that refeed frequently (every 2-3 d)(4).

260 ot product or the Euclidean distance between vectors that represent spectra, a deep convolutional neu

261 Ticks are important vectors that transmit several pathogens including human

262 pathogen-carrying mosquito species (disease vectors) that pose a health risk to humans and livestock

263 The angular distance between CWB-vectors then provides a single quantitative variable des

264 ppropriate ER signal sequence and expression vector, this simple technology can likely be used with m

265 s, are generally represented as a continuous vector through an embedding matrix.

266 Among arthropod vectors, ticks transmit the most diverse human and anima

267 , we first construct a comprehensive feature vector to effectively extract the global and local infor

268 followed by a modified Vaccinia virus Ankara vector to induce HBV-specific B- and T-cell responses.

269 ic repeats-Cas9 (CRISPR-Cas9) and transposon vectors to disrupt Trp53 and overexpress C-Myc (Trp53(KO

270 ate the effects of such factors, we used AAV vectors to express isoforms of the antiinflammatory cyto

271 Ape Adenoviral and Modified Vaccinia Ankara vectors to generate a viral-vectored vaccine, referred t

272 previously designed a library of lentiviral vectors to generate somatic-transgenic rodents to monito

273 Use of viral vectors to override transmitter switching blocks the ben

274 nematodes linking Nb-mediated resistance to vector transmission.

275 by direct contact was about twice as high as vector transmission.

276 Unlike other vector-transmitted diseases, our results show that Leuco

277 redict infection prevalence and diversity of vector-transmitted parasites.

278 Mites are notorious for being vectors transmitting infectious pathogens and source of

279 ency (by optimizing the transgene cassette), vector tropism (using capsid engineering) and the abilit

280 F) of the segment 7 (pT7/NSP3) transcription vector used in the RG system with an ORF encoding NSP3 f

281 dentifying typhoon track vectors, clustering vectors using a self-organizing map, extracting flow cha

282 L-2 and also has applications as a candidate vectored vaccine to elicit protective immunity against S

283 unogenicity of a novel chimpanzee adenovirus-vectored vaccine, ChAdOx1 nCoV-19 (AZD1222), in young ad

284 Vaccinia Ankara vectors to generate a viral-vectored vaccine, referred to as Nous-209.

285 ions in individual bats, implying that DrBHV-vectored vaccines might invade despite the highly preval

286 Virally vectored vaccines that spread autonomously through bat p

287 ) F protein to direct incorporation into the vector virion for increased immunogenicity.

288 portant role for symbiotic microorganisms in vector-virus interactions which could potentially be use

289 rating the exceptional safety profile of the vector vis-a-vis systemic utility.

290 Each vector was defined by structural (x-axis) and functional

291 Finally, a solvent-exposed vector was defined from the pyridazinone template to ena

292 A transferable 'all-in-one' vector was functional in Escherichia coli, Pseudomonas s

293 cloned into the pCI-neo mammalian expression vector was overexpressed in the testis, to better unders

294 Previously, this vector was used for interferon-beta gene transfer in mou

295 i, in which pooled transfections of multiple vectors were critical to increasing scale and throughput

296 Co-administration of a UV inactivated Ad4 vector with the Ad5-prM-E vaccine led to a significant r

297 the brain delivery of recombinant adenoviral vectors with neuronal-specific expression of human LRRK2

298 l components of the terahertz electric field vector without cross-talk.

299 -house production of small quantities of AAV vector without the need for specialized equipment.

300 A viral vector, Zucchini yellow mosaic virus (ZYMV), was employe