ライフサイエンスコーパス: vertebral

1 ctal septum malformation, caudal regression, vertebral-anal-cardiac-tracheo-esophageal fistula-renal-

2 ause of the presence of collateral occipital-vertebral anastomosis.

3 he cerebral circulation with emphasis on the vertebral and basilar arteries (the posterior cerebral c

4 en with severe osteoporosis, the risk of new vertebral and clinical fractures is significantly lower

5 ures, clinical fractures (a composite of non-vertebral and symptomatic vertebral), and non-vertebral

6 ore atherosclerotic stenosis or occlusion in vertebral and/or basilar arteries underwent large-vessel

7 a composite of non-vertebral and symptomatic vertebral), and non-vertebral fractures.

8 herapy [RRT]) and bone events (incident hip, vertebral, and all fractures).

9 We sought the genetic cause of cardiac, vertebral, and renal defects, among others, in unrelated

10 Vertebral anomalies in caudal regression syndrome may ar

11 D, central nervous system (CNS) dysfunction, vertebral anomalies, and dysmorphic features and were fo

12 rt stature, growth-plate irregularities, and vertebral anomalies, such as scoliosis.

13 enesis and the pathogenesis of lumbar/sacral vertebral anomalies.

14 n of MMC involves failure in neural tube and vertebral arch closure at early gestational ages, follow

15 Vertebral arch elements were present in early stem verte

16 ysis occurs, including the postzygopophysis, vertebral arch, and spinous process, which causes biomec

17 nts: the vertebral body (or centrum) and the vertebral arches.

18 sonography at the internal carotid (ICA) and vertebral arteries (VA).

19 ae leads to a complete loss of the bilateral vertebral arteries (VTAs) that extend along the ventrola

20 Imaging data on the patency of the vertebral arteries and posterior communicating arteries,

21 ressure assessed at the internal carotid and vertebral arteries.

22 tid arteries (ICA and ECA, respectively) and vertebral artery (VA) (Duplex ultrasound) was measured.

23 red at the internal carotid artery (ICA) and vertebral artery (VA) and CBF velocity at the middle cer

24 ssive heat stress provoked ~16% increases in vertebral artery blood flow, independent of changes in e

25 using validated diagnosis codes for carotid/vertebral artery dissection.

26 ence of congenital cerebrovascular variants; vertebral artery hypoplasia, and an incomplete posterior

27 .6, 2.4]; P < .001), carotid injuries versus vertebral artery injuries (49 of 420 [11.7%] vs 35 of 66

28 No patients with isolated vertebral artery injuries had positive transcranial Dopp

29 injuries, but monitoring was not useful for vertebral artery injuries.

30 Traumatic vertebral artery injury (TVAI) can have a varied clinica

31 elayed stroke among patients who sustained a vertebral artery injury with or without additional vesse

32 ulted from carotid injury and 4 (26.7%) from vertebral artery occlusion (P = .03).

33 Vertebral artery stenosis can be treated with stenting w

34 Symptomatic vertebral artery stenosis is associated with a high risk

35 than the 'less-reactive' CA measured at the vertebral artery that was associated with WMH severity.

36 e, and vessel type (internal carotid artery, vertebral artery) with BCVI-associated stroke.

37 otected areas (ie, not dependent on the left vertebral artery).

38 ion (CeAD), a mural hematoma in a carotid or vertebral artery, is a major cause of ischemic stroke in

39 Vertebral augmentation (VA), defined as either vertebrop

40 ertebral compression fractures who underwent vertebral augmentation were 22% less likely to die at up

41 o independent readers visually evaluated all vertebral bodies (n = 163) for the presence of abnormal

42 In adult mice, fusion of vertebral bodies and of spinous and transverse processes

43 Chordomas are tumors that arise at vertebral bodies and the base of the skull.

44 Five porcine vertebral bodies in one pig underwent intervention (IRE

45 hod and using the activity concentrations in vertebral bodies in SPECT images at 24 h after injection

46 measure bone density of thoracic and lumbar vertebral bodies on computed tomographic (CT) images.

47 tebral bodies, heterogeneous signal from the vertebral bodies on T2 TIRM images, well-defined paraspi

48 es, hyperintense/homogeneous signal from the vertebral bodies on T2 TIRM images.

49 ing penumbra, and bone marrow from the L3-L5 vertebral bodies was contoured on pretreatment FDG PET/C

50 Failure load of the vertebral bodies was determined from destructive biomech

51 Twelve thoracic vertebral bodies were removed from three human cadavers

52 VNCa images were significantly different in vertebral bodies with and without edema (P < .001).

53 focal/heterogeneous contrast enhancement of vertebral bodies, heterogeneous signal from the vertebra

54 f vertebral bodies, low-grade destruction of vertebral bodies, hyperintense/homogeneous signal from t

55 diffuse/homogeneous contrast enhancement of vertebral bodies, low-grade destruction of vertebral bod

56 te cancer cells were either coimplanted with vertebral bodies, or inoculated in the tibiae of immunoc

57 cic spine, involvement of 2 or more adjacent vertebral bodies, severe destruction of the vertebral bo

58 anterolateral spinal column at four adjacent vertebral bodies.

59 f 98.3% for the differentiation of edematous vertebral bodies.

60 attenuation of the trabecular bone of the L5 vertebral body (L5HU) was measured.

61 , each consisting of two key components: the vertebral body (or centrum) and the vertebral arches.

62 h plates, and therefore include at least the vertebral body and arch.

63 f the abdominal aorta at the level of the L3 vertebral body and its associations with multiple variat

64 on chest radiograph with destruction of the vertebral body and preservation of the disc space.

65 In lumbar vertebrae reduced vertebral body area and wall thickness were accompanied

66 This study illustrated that the vertebral body BMD values of the patients with scoliosis

67 OO was in the vertebral body for 18 of 57 patients, the neural arch fo

68 There were 141 thoracic and lumbar vertebral body fractures in the case set.

69 er system detects and anatomically localizes vertebral body fractures in the thoracic and lumbar spin

70 ith positive findings for fractures (59 with vertebral body fractures) and 10 control examinations (w

71 BMD were performed by QCT analysis for each vertebral body from T12 to L5, and mean BMD was calculat

72 educe pain and further collapse and/or renew vertebral body height by introducing bone cement into fr

73 l dynamic radiographic imaging of the lumbar vertebral body motion.

74 The metastases-to-vertebral body signal intensity ratio (MVR) was calculat

75 rea at the fifth, eighth, and tenth thoracic vertebral body was quantified.

76 ose single-section quantitative CT of the L4 vertebral body with use of a calibration phantom.

77 muscle, abdominal fat, lower thoracic spine, vertebral body, and humeral head.

78 vertebral bodies, severe destruction of the vertebral body, focal/heterogeneous contrast enhancement

79 Bone needle was inserted into the vertebral body, followed by injection of PMMA cement.

80 wer chondrogenic cells within the developing vertebral body, which fail to condense appropriately alo

81 N, or occurrence of first fracture (eg, hip, vertebral body, wrist).

82 rienced relapse, with painful collapse of L3 vertebral body.

83 ance in 1984 due to a hemangioma of cervical vertebral body.

84 false-positive rate, as well as to calculate vertebral bone density, on CT images.

85 s the spine curves increasingly over time as vertebral bone formation compresses the notochord asymme

86 Vertebral bone marrow lesions had a male predominance an

87 ine its role in bone we analyzed femoral and vertebral bone mass by micro-computed tomography analysi

88 61.4 years +/- 11.8) performed for suspected vertebral bone metastases were included in this retrospe

89 measuring using computed tomography thoracic vertebral bone mineral density (BMD) and fracture preval

90 were all well rendered alongside surrounding vertebral bone structure.

91 akabuti's ancestry, we used deep sampling of vertebral bone, under X-ray control, to obtain non-conta

92 e connected, and the developmental origin of vertebral bone-mineralizing cells.

93 ad normal hematopoiesis but reduced limb and vertebral bone.

94 n and spinal cord alignment to occipital and vertebral bones is crucial for coherent neural and skele

95 the dorsal vertebra resembling the detached vertebral bony structure when spondylolysis occurs, incl

96 SOE), whereas 4 years of raloxifene reduced vertebral but not nonvertebral fractures.

97 resulted in soft-tissue contrast within the vertebral canal, despite evident nervous tissue deterior

98 meningeal hemorrhages or deformities of the vertebral canal.

99 eletal disorder characterized by progressive vertebral, carpal and tarsal fusions, and mild short sta

100 - unossified regions in the middle of caudal vertebral centra - that in many extant squamates allow t

101 osteoblast-independent mechanism for teleost vertebral centra formation.

102 This problem is especially complex given the vertebral chain of sympathetic ganglia derive secondaril

103 y and sympathetic ganglia and form metameric vertebral circuits connecting to lymph nodes and the tho

104 morphic) life cycle had an increased rate of vertebral column and body form diversification compared

105 of the segmented embryonic precursors of the vertebral column and musculature.

106 rmal development of the caudal aspect of the vertebral column and the spinal cord., It results in neu

107 Extrinsic vertical muscles attach to the vertebral column and the swimbladder.

108 Histologic sections of the vertebral column at embryonic days 15.5 and 17.5 reveale

109 known complete hominin cervical and thoracic vertebral column before 60,000 years ago.

110 The segmented vertebral column comprises a repeat series of vertebrae,

111 t xenarthran mammals, which strengthened the vertebral column for locomotion.

112 The vertebral column in the sacral area has large anterior a

113 The mammal vertebral column is a classic example of a metameric str

114 Formation of the vertebral column is a critical developmental stage in ma

115 The segmental organization of the vertebral column is established early in embryogenesis,

116 The mammalian vertebral column is highly variable, reflecting adaptati

117 he close proximity of the spinal cord to the vertebral column limits many conventional therapeutic op

118 Here we show an extended vertebral column LV network using three-dimensional imag

119 o previous studies, we show that most of the vertebral column of the Berlin Archaeopteryx possesses i

120 ntiated from the teratoma by the presence of vertebral column often with an appropriate arrangement o

121 The vertebral column or spine assembles around the notochord

122 The mammalian vertebral column provides an opportunity to test these h

123 ation, including re-patterning of the caudal vertebral column that is otherwise only seen in salamand

124 d signals are essential for formation of the vertebral column the phenotypes suggested that the lacZ

125 This reinforced vertebral column, combined with the extensive developmen

126 aside the developmentally abnormal Kebara 2 vertebral column, La Chapelle-aux-Saints 1 is joined by

127 ed exclusively in mild defects in the caudal vertebral column.

128 Although several complete lumbar vertebral columns are known for early hominins, to date,

129 en competing hypotheses for the evolution of vertebral complexity by incorporating fossil data from t

130 nts may have provided impetus for increasing vertebral complexity in mammals.

131 Particular controversy surrounds whether vertebral component structures are homologous across ver

132 Background Osteoporotic vertebral compression fractures (OVCFs) are prevalent, w

133 etect, anatomically localize, and categorize vertebral compression fractures at high sensitivity and

134 iction of bone marrow edema in thoracolumbar vertebral compression fractures in patients with osteopo

135 ve the detection rate of acute thoracolumbar vertebral compression fractures in patients with osteopo

136 2 million patients, those with osteoporotic vertebral compression fractures who underwent vertebral

137 trate that human XylT2 deficiency results in vertebral compression fractures, sensorineural hearing l

138 traumatic bone marrow edema in patients with vertebral compression fractures.

139 for assessing traumatic bone marrow edema in vertebral compression fractures.

140 d on running speed, positional behaviour and vertebral contribution to locomotion.

141 rs with polymeric foam to replicate both the vertebral corticocancellous interface and surface anatom

142 The consistent vertebral count indicates a tight control of axial patte

143 Vertnin genotype significantly affected vertebral counts as well.

144 n the mouse causes cerebellar hypoplasia and vertebral defects.

145 Vertebral delineation should include all primary ossific

146 ebrates, much remains to be understood about vertebral development and evolution.

147 et Ctgf, indicates that Fat4-Dchs1 regulates vertebral development independently of Yap and Taz.

148 hin these genes will expand our knowledge on vertebral development using natural genetic variants seg

149 The importance of the Hox gene families in vertebral development was highlighted as significant ass

150 ered with some notochord-dependent aspect of vertebral development.

151 nce of hypoplastic, aplastic or fetal PCoAs, vertebral dominance, and diameters and angles of surroun

152 , amlodipine-benazepril, and quinapril), non-vertebral fracture (for alendronate and calcitonin), psy

153 men with at least two moderate or one severe vertebral fracture and a bone mineral density T score of

154 and matched pair analyses were performed on vertebral fracture and patient levels.

155 networks can identify vertebral fractures on vertebral fracture assessment images with high accuracy,

156 points were the cumulative incidence of new vertebral fracture at 24 months and the cumulative incid

157 ts in this rare case of traumatic complex C2 vertebral fracture caused by a gunshot injury.

158 with bisphosphonates to reduce the risk for vertebral fracture in men who have clinically recognized

159 eoporosis who were suspected of having acute vertebral fracture underwent DE CT and MR imaging.

160 ients with hyperkyphosis due to osteoporotic vertebral fracture were compared with those of the contr

161 nical fracture (nonvertebral and symptomatic vertebral fracture) at the time of the primary analysis

162 There were 7.48 hip fracture, 8.18 vertebral fracture, 1.14 AFF, 0.21 esophageal cancer and

163 ter stratification for previous radiographic vertebral fracture, and treatment was masked to study pa

164 hip fracture, while secondary outcomes were vertebral fracture, atypical femoral fracture (AFF), ost

165 with a previous hip fracture, more than one vertebral fracture, or a T-score of less than -4.0 at th

166 en -2.5 and -4.0 if no previous radiographic vertebral fracture, or between -1.5 and -4.0 with a prev

167 Patients who had vertebral fracture, spondylitis-spondylodiscitis, tumour

168 re, or between -1.5 and -4.0 with a previous vertebral fracture.

169 ients with hyperkyphosis due to osteoporotic vertebral fracture.

170 ures (zoledronic acid; low SOE) and clinical vertebral fractures (alendronate; moderate SOE) but not

171 .64 [95% CI, 0.50 to 0.82]) and radiographic vertebral fractures (both moderate SOE), whereas 4 years

172 ut alendronate users are more likely to have vertebral fractures (HR 1.07, 95% CI 1.01-1.14).

173 nvertebral fractures (high SOE) and clinical vertebral fractures (moderate SOE).

174 ower fat mass persisted as a risk factor for vertebral fractures (odds ratio, 1.23; 95% confidence in

175 ctures (ranging from 0.90% to 1.86%) and non-vertebral fractures (ranging from 0.84% to 2.55%) remain

176 The yearly incidence of new vertebral fractures (ranging from 0.90% to 1.86%) and no

177 aloxifene was associated with lower risk for vertebral fractures (RR, 0.61 [95% CI, 0.53-0.73]; 2 tri

178 Background Detection of vertebral fractures (VFs) aids in management of osteopor

179 versus discontinuation reduced radiographic vertebral fractures (zoledronic acid; low SOE) and clini

180 odanacatib versus placebo were: radiographic vertebral fractures 3.7% (251/6770) versus 7.8% (542/691

181 odanacatib versus placebo were: radiographic vertebral fractures 4.9% (341/6909) versus 9.6% (675/701

182 versus 1.6% (125/8028), 0.53, 0.39-0.71; non-vertebral fractures 5.1% (412/8043) versus 6.7% (541/802

183 versus 2.0% (162/8028), 0.52, 0.40-0.67; non-vertebral fractures 6.4% (512/8043) versus 8.4% (675/802

184 t least one other timepoint, and hip and non-vertebral fractures adjudicated as being a result of ost

185 Primary endpoints were incidence of vertebral fractures as assessed using radiographs collec

186 utcomes included new vertebral, hip, and non-vertebral fractures as well as bone mineral density (BMD

187 Raloxifene may prevent vertebral fractures but may not improve BMD (low SOE).

188 bral hemangioma, in another 4 - pathological vertebral fractures due to metastases, and in one case -

189 The corresponding percentages of vertebral fractures for DXA and quantitative CT with a 5

190 nd reduced the incidence of new radiographic vertebral fractures in 1 high-quality trial.

191 or denosumab to reduce the risk for hip and vertebral fractures in women who have known osteoporosis

192 lure, RRT, all fractures, hip fractures, and vertebral fractures occurred in 0.6%, 0.2%, 0.7%, 0.1%,

193 At 24 months, new vertebral fractures occurred in 28 (5.4%) of 680 patient

194 n Convolutional neural networks can identify vertebral fractures on vertebral fracture assessment ima

195 hese convolutional neural network-identified vertebral fractures predict clinical fracture outcomes.

196 period of 24 months, a 48% lower risk of new vertebral fractures was observed in the romosozumab-to-a

197 bone mineral density, microarchitecture, and vertebral fractures were assessed at baseline (after int

198 The majority of vertebral fractures were identified at baseline (23% of

199 deficiency, bone markers abnormalities, and vertebral fractures were observed shortly after HTx.

200 Non-vertebral fractures were reported in 292 individuals, 15

201 two consecutive patients with 37 morphologic vertebral fractures were studied between October 2015 an

202 ctures) and 10 control examinations (without vertebral fractures), were performed.

203 Denosumab also reduces risk for radiographic vertebral fractures, based on 1 trial.

204 comes included new and worsened radiographic vertebral fractures, clinical fractures (a composite of

205 ertebral and symptomatic vertebral), and non-vertebral fractures.

206 The primary outcome was new radiographic vertebral fractures.

207 aratide reduces the risk of nonvertebral and vertebral fractures.

208 ment beyond 3 to 5 years may reduce risk for vertebral fractures.

209 ab reduce the risk of hip, nonvertebral, and vertebral fractures; bisphosphonates are commonly used a

210 Non-vertebral fragility fractures occurred in 25 (4.0%) pati

211 The origin of vertebral functional diversity does not correlate with t

212 is a skeletal malformation characterized by vertebral fusion.

213 region, and the distal pygostyle, formed by vertebral fusion.

214 Moreover, the vertebral fusions in persons with MPS, coupled with evid

215 zed by pterygia, camptodactyly of the hands, vertebral fusions, and scoliosis.

216 hin the spine may lead to the development of vertebral fusions.

217 e spinal movement, and the implantation of a vertebral glass window without interfering animals' moto

218 by subsequent impairment in spinal cord and vertebral growth during fetal development.

219 Vertebral haemangiomas are incidental findings in imagin

220 cases the reason for vertebroplasty was the vertebral hemangioma, in another 4 - pathological verteb

221 Vertebral hemangiomas being the most common of all are s

222 Secondary outcomes included new vertebral, hip, and non-vertebral fractures as well as b

223 Hox genes are known to determine vertebral identity along with being required for normal

224 As is essential both for properly patterning vertebral identity at different axial levels and for mod

225 on a single CT section obtained at the L4-5 vertebral interface.

226 and who underwent CT that included the L4-5 vertebral interspace were included.

227 imaging to differentiate these two groups of vertebral lesions.

228 The lumbar vertebral level 4/5 IVDs harvested from 15-day-, 4- and

229 ant WM atrophy was detected at each cervical vertebral level in C9(+) subjects older than 40 years wi

230 ional muscle area and bone density at the L3 vertebral level, compared with a group with no sarcopeni

231 eletal muscle cross-sectional area at the L3 vertebral level, normalized to height.

232 d subcutaneous adipose tissue (SAT) areas at vertebral levels T7 to L5.

233 umbar spinal stenosis at one or two adjacent vertebral levels to undergo either decompression surgery

234 in the corona radiata and between C2 and C4 vertebral levels.

235 Therefore, vertebral LVs add to skull meningeal LVs as gatekeepers

236 Vertebral LVs connect to peripheral sensory and sympathe

237 Vertebral LVs remodel extensively after spinal cord inju

238 after spinal cord injury and VEGF-C-induced vertebral lymphangiogenesis exacerbates the inflammatory

239 ized disruption of notochord vacuoles causes vertebral malformation and curving of the spine axis at

240 Congenital scoliosis is a common type of vertebral malformation.

241 Congenital vertebral malformations (CVMs) are associated with human

242 resses the notochord asymmetrically, causing vertebral malformations and kinking of the axis.

243 osine protein kinase (dstyk) lead to CS-like vertebral malformations in zebrafish.

244 growth, occurs in the absence of congenital vertebral malformations or neuromuscular defects [1].

245 teristic facial features, heart defects, and vertebral malformations.

246 a complex genetic disorder characterized by vertebral malformations.

247 Vertebral marrow lesions can be differentiated as benign

248 The vertebral maturation pattern and extended brain growth m

249 L3 and L4 vertebral mineral bone density, assessed by dual-energy

250 ertebrates is the specification of different vertebral morphologies, with an additional role in axis

251 Craniodental morphology, tooth wear, torso vertebral morphology, and body size all suggest that Ank

252 e cycle complexity explain the variations in vertebral number and adult body form better than larval

253 ating, multiple genetic networks controlling vertebral number and identity, miR-196 is a critical pla

254 that selection against changes in presacral vertebral number led to stasis in mammals that rely on d

255 and 196b act redundantly to constrain total vertebral number.

256 ve not shown any benefit in the treatment of vertebral or basilar artery stenosis.

257 all patients with reported internal carotid, vertebral, or suspected intracranial artery aneurysms we

258 The mass had vertebral organization, limb and pelvic bones.

259 fessionals who care for patients with native vertebral osteomyelitis (NVO).

260 such as meningitis, epidural abscess, and/or vertebral osteomyelitis.

261 omologous across vertebrates, how somite and vertebral patterning are connected, and the developmenta

262 ailed mechanisms that regulate and diversify vertebral patterning.

263 We show the potential for vertebral patterns to confer heightened sensitivity, wit

264 se line recapitulates a similar but worsened vertebral phenotype featured by lamellar isthmus.

265 Vertebral precursors, called somites, provide one of the

266 ox genes, which are collinearly activated in vertebral precursors, repress Wnt activity with increasi

267 l pair of protractor muscles associated with vertebral processes (elastic spring mechanism), is invol

268 There is a need for multicentre research on vertebral radiotherapy dose distributions for children,

269 information, it is advised that homogeneous vertebral radiotherapy doses should be delivered in chil

270 n oncologists who have patients that require vertebral radiotherapy.

271 a century ago, recent studies of Neandertal vertebral remains have inferred a hypolordotic, flat low

272 joined by other Neandertals with sufficient vertebral remains in providing them with a fully upright

273 often occurred in the extracranial carotid, vertebral, renal, and coronary arteries.

274 ies such as spondylolisthesis, scoliosis and vertebral segmentation anomalies and previous surgery in

275 These hits provide insight into human vertebral segmentation disorders and myopathies.

276 However, the mode of vertebral segmentation varies considerably between major

277 elitis episodes and extended a median of two vertebral segments (range, 1-12); in 21 of 48 (44%) ring

278 ubpial gadolinium enhancement extending >/=2 vertebral segments and persistent enhancement >2 months

279 Short transverse myelitis (STM; <3 vertebral segments) is considered noncharacteristic of n

280 ly extensive (greater than or equal to three vertebral segments) T2-hyperintensity in 44 of 50 (88%)

281 inal cord T2-hyperintense lesion less than 3 vertebral segments, AQP4-IgG seropositivity, and a final

282 panied by a spinal cord lesion spanning >/=3 vertebral segments.

283 Here, using numerous vertebral series, histology, and X-ray computed tomograp

284 Consistently, partial ablation of Slc26a2 in vertebral skeletal cells using Col1a1-Cre; Slc26a2 (fl/f

285 The vertebral skeleton is a defining feature of vertebrate a

286 Analyses were performed for vertebral stenosis at any location and separately for ex

287 Stenting for vertebral stenosis has a much higher risk for intracrani

288 nting with medical treatment for symptomatic vertebral stenosis.

289 dical treatment in patients with symptomatic vertebral stenosis.

290 We aimed to compare vertebral stenting with medical treatment for symptomati

291 However, broad differences in vertebral structures and morphogenetic strategies occur

292 -ganglionic neurons that comprise a chain of vertebral sympathetic ganglia, arises developmentally is

293 rsal fusion and extensive posterior cervical vertebral synostosis, cardiac septal defects with valve

294 GH treatment increased vertebral Tb. bone mass in Control and UL groups but not

295 hese delicate structures are embedded within vertebral tissues and difficult to visualize using tradi

296 lower aortic root strain (P=0.05) and higher vertebral tortuosity index (P=0.01) were independently a

297 notype severity such as aortic stiffness and vertebral tortuosity index have been proposed.

298 Vertebral tortuosity index was calculated as previously

299 congenital malformations, including cardiac, vertebral, tracheo-esophageal, renal and limb defects.

300 onset of scoliosis without malformations of vertebral units.