ライフサイエンスコーパス: vesiculation

1 rdance with the theory of lipid disc micelle vesiculation.

2 ses during Golgi disassembly: unstacking and vesiculation.

3 translocation and its role in extracellular vesiculation.

4 is required solely for EGF-stimulated inward vesiculation.

5 t may be required for a late stage in inward vesiculation.

6 shes the effect of EGF stimulation on inward vesiculation.

7 to thrombin rather than by inducing platelet vesiculation.

8 smembrane phospholipid movement and membrane vesiculation.

9 ty in the cytoplasm, with no plasma membrane vesiculation.

10 3, and the need for PLD1 activation in Golgi vesiculation.

11 2 and phosphatidic acid (PA) during membrane vesiculation.

12 mitosis, with little or no fragmentation and vesiculation.

13 echanically induced membrane deformation and vesiculation.

14 activated alpha subunit, that triggers Golgi vesiculation.

15 f membrane lipids and proteins and decreased vesiculation.

16 spholipid asymmetry and results in decreased vesiculation.

17 ll's outer leaflet upon in vitro storage and vesiculation.

18 connections to the modes of plant endosomal vesiculation.

19 ired for ESCRT-III disassembly and endosomal vesiculation.

20 ocesses such as endocytosis, tubulation, and vesiculation.

21 externalization, including cell division and vesiculation.

22 have unique roles in the mechanisms of COPII vesiculation.

23 f the C5b-9 complexes by endocytosis and exo-vesiculation.

24 over-expression of Cav-1 increased C5b-9 exo-vesiculation.

25 s that may correspond to regions of membrane vesiculation.

26 nto evaluating mechanisms for outer membrane vesiculation.

27 erize the process of liposome tubulation and vesiculation.

28 n MAC deposition and MAC-mediated damage and vesiculation.

29 that shorter forms of PA and DAG promote the vesiculation ability of COPI fission factors.

30 n vitro hemolysis, and the highest degree of vesiculation, accompanied by increases in lipid peroxida

31 physical design principles to ensure robust vesiculation against opposing forces like membrane tensi

32 h are disintegrated by membrane blebbing and vesiculation, aging lens fiber cells are compressed into

33 d into tubular extensions that later undergo vesiculation, allowing transport vesicles to move along

34 ion of purified EHD proteins to reconstitute vesiculation allows us to assess the ability of each pro

35 in membrane integrity, an increased membrane vesiculation and a dependance on otherwise non-essential

36 e disentangled by these chaperons to achieve vesiculation and acrosomal contents release.

37 after protracted loss of OM material through vesiculation and blebbing at cell-division sites and com

38 taining by immunofluorescence assay, and the vesiculation and breakdown of the internal parasite ultr

39 he endosomal membrane where they mediate its vesiculation and cargo sequestration.

40 atric disorders and other conditions, aging, vesiculation and cell division).

41 ew fiber growth was disordered and displayed vesiculation and density variations.

42 Inner-membrane vesiculation and dissociation of ATP synthase dimers wou

43 clude diminished insulin granule content, ER vesiculation and distention, mitochondrial swelling and

44 more versatile function of these proteins in vesiculation and endocytosis beyond their role as scaffo

45 sted of epidermal hydropic change leading to vesiculation and erosion; alternately, or in addition, t

46 field and experimental observations of magma vesiculation and fragmentation resulting from heating (r

47 nsity on self-forming Percoll gradients upon vesiculation and in vitro "aging." Uptake of vesiculated

48 is a ubiquitous eukaryotic membrane budding, vesiculation and internalization process fulfilling nume

49 We further demonstrated that vesiculation and plasma membrane enclosure at the site o

50 production of extracellular polysaccharides, vesiculation and protein secretion.

51 e apical membrane of damaged cells exhibited vesiculation and shedding of microvilli.

52 ns with the vascular systems through altered vesiculation and TF shedding.

53 has the intrinsic ability to induce membrane vesiculation and to incorporate NC-like structures into

54 ar mechanism of ENTH-domain-induced membrane vesiculation and tubulation and the implications of the

55 Liposome remodeling processes (e.g., vesiculation and tubulation) due to N-BAR domain interac

56 new insight for their differential roles in vesiculation and tubulation, respectively.

57 embrane curvature induction is different for vesiculation and tubulation, these data also explain why

58 taneous curvature, and membrane stiffness on vesiculation and vesicle size distribution were investig

59 multiple points with the acrosomal membrane (vesiculation) and syntaxin and VAMP are shed with the re

60 , band 3, triggers membrane destabilization, vesiculation, and fragmentation, we discovered a SH2 sig

61 creased cell wall apposition and cytoplasmic vesiculation, and induction of callose deposition.

62 canonical inflammasome activator ATP-induced vesiculation, and it is dependent on the autocrine IFN s

63 BB, including membrane tethering defects, MV vesiculation, and membrane shedding.

64 level surface fibrinogen retention, membrane vesiculation, and procoagulant activity.

65 r the sequence of events leading to budding, vesiculation, and secretion; and PxB-mediated transfer b

66 f the ENTH domain of epsin leads to liposome vesiculation, and that epsin is required for clathrin-co

67 ets treated with RO318220 suggested platelet vesiculation as a result of RO318220 treatment; however,

68 onally compromised GAPDH identifies enhanced vesiculation as a self-protective mechanism in ex vivo a

69 x in nuclear envelope breakdown, implicating vesiculation as an important step.

70 sed on membrane integrity and by cytoplasmic vesiculation as evidence of piecemeal degranulation.

71 Our novel vesiculation assay and in vitro electron microscopy anal

72 It undergoes extensive vesiculation at the onset of mitosis and its reassembly

73 some exocytosis, exosome formation, membrane vesiculation, autophagy, and pyroptosis.

74 of recombinant proteins, using a hypertonic vesiculation buffer containing chloride salts and no for

75 ossible roles of these components in driving vesiculation by constructing a quantitative model of the

76 ysis of the energetics and thermodynamics of vesiculation by recourse to nonlinear elasticity, taking

77 The extent of vesiculation by these proteins and vesicle size depend o

78 OP-I recruitment, the role of COP-I in Golgi vesiculation caused by expression of the dominant activa

79 c14p, which also suppresses the uncontrolled vesiculation caused by the cytosolic subfraction.

80 e microtubule and vimentin cytoskeletons, ER vesiculation, chromatin decondensation and nuclear round

81 These experiments suggest that vesiculation contributes to alterations in membrane lipi

82 AR domain of Pacsin and mutagenesis studies, vesiculation could be linked to the presence of unique s

83 erturbed in the absence of Clc, resulting in vesiculation defects.

84 ation of the process of C5b-9 removal by exo-vesiculation demonstrated that inhibition of Cav-1 and c

85 phatidyl-choline were monitored for age- and vesiculation-dependent changes in cell density, membrane

86 Here, we show that phagolysosome vesiculation depends on amino acid export by the solute

87 and was preceded by PV membrane indentation, vesiculation, disruption, and, surprisingly, stripping o

88 Endophilin, which participates in membrane vesiculation during receptor-mediated endocytosis, is a

89 dynamin (Dyn2) has been implicated in Golgi vesiculation during secretion, we tested whether inhibit

90 by Src kinase regulates Golgi integrity and vesiculation during the secretory process.

91 eased levels of lipopolysaccharide, membrane vesiculation, dynamic shrinking and extension of the cyt

92 Mutations that cause increased vesiculation enhance bacterial survival upon challenge w

93 rce from actin polymerization enables robust vesiculation even at high membrane tensions.

94 nesis and for a series of "reverse topology" vesiculation events.

95 dding is more complex than current models of vesiculation from flat membranes.

96 results demonstrate VP40 selectively induces vesiculation from membranes containing phosphatidylserin

97 erefore, that the mechanism of AP-3-mediated vesiculation from neuroendocrine endosomes requires the

98 g proteins are required for the AP2-mediated vesiculation from the plasma membrane, but not from endo

99 of cPLA2alpha did not increase the endosomal vesiculation, implying a requirement for additional fact

100 The NEC drives nuclear envelope vesiculation in cells, but the precise budding mechanism

101 binant O-PS biosynthesis is coordinated with vesiculation in laboratory strains of Escherichia coli t

102 during HSV-1 infection and nuclear envelope vesiculation in NEC-transfected cells.

103 peptide release supports a dynamic role for vesiculation in NTHI pathogenesis and clinically relevan

104 ation of AlgU, since stress caused increased vesiculation in strains lacking algU.

105 of OS resulted in loss of photoresponse and vesiculation in the OS.

106 mpression that induced melting and extensive vesiculation in the tektite melt.

107 Erythrocyte vesiculation in vitro produced MPs loaded with heme.

108 t mitotic Golgi breakdown proceeds by direct vesiculation independent of the ER.

109 vature as it tubulates liposomes and induces vesiculation into giant unilamellar vesicles, effects th

110 We conclude that ARF-mediated vesiculation into synaptic vesicle-sized organelles uses

111 We find that IQ-mediated Golgi vesiculation is inhibited by G alpha(s)-GDP and G alpha(

112 Vesiculation is mediated by the COPI budding machinery A

113 stops membrane disassembly, suggesting that vesiculation is necessary.

114 N-BAR spontaneous curvature fields, whereas vesiculation is only observed with isotropic N-BAR spont

115 Here, we show that Golgi vesiculation is required for progression to metaphase.

116 This inward vesiculation is specific for AnxA2 and not shared with o

117 protein involved in membrane tubulation and vesiculation, is essential for successful cytokinesis.

118 lation mutant strains did not correlate with vesiculation levels, demonstrating that vesicle producti

119 further mechanistic studies to identify the vesiculation machinery that regulates OMV secretion and

120 a during ascent strongly controls degassing, vesiculation, magma strength and the effusive-explosive

121 null mutants were recovered, suggesting that vesiculation may be a fundamental characteristic of gram

122 orks of concatenated vesicle buds by a novel vesiculation mechanism.

123 Such changes, rather than vesiculation mechanisms, also underlie the redistributio

124 ess, and growth characteristics of the novel vesiculation mutant strains did not correlate with vesic

125 Only a few low-vesiculation mutants and no null mutants were recovered,

126 Prospects of vesiculation occurring during splenic flow of erythrocyt

127 Our findings reveal that IQ-mediated Golgi vesiculation occurs through activation of heterotrimeric

128 es highlight the importance of annexin A2 in vesiculation of a population of Atg16L-positive structur

129 f small areas of plasma membrane followed by vesiculation of apposed membranes.

130 fier cPLA2alpha and EHD1 are involved in the vesiculation of CD59-containing endosomes.

131 Budding and vesiculation of erythrocyte membranes occurs by a proces

132 sequence seen during spontaneous inside-out vesiculation of erythrocyte membranes suggests that the

133 of PLD1, recruitment of COP-I to Golgi, and vesiculation of Golgi in cells are functionally separabl

134 studies support a role for cPLA2alpha in the vesiculation of GPI-AP-containing membranes, using endog

135 nerate sufficient heat to induce melting and vesiculation of hydrated silicic magma.

136 fied AMPH-1 is sufficient for tubulation and vesiculation of liposomes in a mechanism that is regulat

137 ant unilamellar vesicles by inducing massive vesiculation of liposomes.

138 the mitochondrial membrane potential, induce vesiculation of mitochondria, and induce elevated poly (

139 esulting complement activation initiates the vesiculation of myelin.

140 They cause dramatic vesiculation of new plasma membranes, and destabilize th

141 icular transport defects including unpacking/vesiculation of rhabdomeres, endocytosis of novel vesicl

142 lesion detectable by electron microscopy was vesiculation of rod discs, followed by disruption of out

143 nsport carriers, and to prevent uncontrolled vesiculation of TGN during protein transport.

144 mals (3/12) had APCs that involved prominent vesiculation of the anterior cortex.

145 bility, abnormal morphology, and spontaneous vesiculation of the cells; and 4) the above on/off rates

146 By reconstituting the IQ-mediated vesiculation of the Golgi apparatus in permeabilized cel

147 and their overactivation results in complete vesiculation of the Golgi apparatus.

148 PII coat to stress granules (SGs) leading to vesiculation of the Golgi complex and arrest of ER expor

149 spholipase C- and protein kinase D-dependent vesiculation of the Golgi in HeLa cells; Golgi-targeted

150 a marine sponge metabolite, causes complete vesiculation of the Golgi stacks.

151 t of proteins to coated pits and helps drive vesiculation of the lipid bilayer.

152 losed that resiniferatoxin treatment induced vesiculation of the mitochondria and the endoplasmic ret

153 glycerol, caused by itself an indiscriminate vesiculation of uncoated Golgi membranes that could be s

154 a morphological assay that Rab2 Q65L caused vesiculation of VTCs that accumulated at 15 degrees C.

155 ll measurements to investigate the impact of vesiculation on the reduction in volume, Hb mass, and me

156 l activity from a non-random process such as vesiculation or bleb formation: channel inactivation by

157 c Golgi breakdown in vivo proceeds by direct vesiculation or involves fusion with the endoplasmic ret

158 amin uses GTP hydrolysis physically to drive vesiculation; others support the view that dynamin acts

159 Here we review the advantage of vesiculation, particularly in a nonpathogenic context, a

160 he ER at M-phase as the result of a two-step vesiculation pathway involving ER-Golgi fusion followed

161 catalyse many of the essential steps in the vesiculation pathway.

162 swelling of endoplasmic reticulum and Golgi vesiculation preceding most nuclear changes and mitochon

163 The most widely used vesiculation procedure relies on formaldehyde and dithio

164 into vesicles for removal indicates that the vesiculation process can act to selectively eliminate un

165 vesicles prepared by a spontaneous, one-step vesiculation process is shown to be by a low affinity sy

166 icle relaxation time scales suggest that the vesiculation process lasted few seconds.

167 ovesiculation of the external hemileaflet, a vesiculation process promoted by the detergent environme

168 be generated from endosomes by a sorting and vesiculation process that requires the heterotetrameric

169 large deformation that may arise during the vesiculation process.

170 in (EHD) ATPase proteins are involved in the vesiculation process.

171 A clearer understanding of such vesiculation processes holds promise for better elucidat

172 The fusing membranes dispersed by vesiculation, rather than simple unfolding of the conjoi

173 rosomal vesicle membrane at multiple points (vesiculation) results in the release of SNAP-25 with the

174 ltiple, independent measurements of membrane vesiculation revealed that fission became spontaneous as

175 A quantitative assay for vesiculation reveals an antagonistic relationship betwee

176 vesicles of MVB after EGF-stimulated inward vesiculation, suggesting that it may be required for a l

177 dings are consistent with reported trends in vesiculation that are believed to occur in cases of vari

178 during mammalian infection, which stimulates vesiculation that expedites bacterial surface exchange a

179 ells leads to an increase in plasma membrane vesiculation that is relatively resistant to energy depl

180 st pathways for further study of erythrocyte vesiculation that point to the criticality of understand

181 e molecular pathway regulating phagolysosome vesiculation that promotes efficient resolution of phago

182 ncreased levels of lipopolysaccharide and OM vesiculation that ultimately undermine the integrity of

183 re enhanced by bubble nucleation and growth (vesiculation) that reduce the density of magma.

184 Our current studies showed that during vesiculation the skeleton did not fragment but rather re

185 Thus, bacteria use outer membrane vesiculation to exchange cell surface components, thereb

186 (subcellular fractionation, plasma membrane vesiculation to isolate pure plasma membrane fractions,

187 h reversal of staining to marked cytoplasmic vesiculation to loss of cellular membrane integrity with

188 herwise offsets lysosomal dynamics including vesiculation, tubulation and fission.

189 ivity, DNA fragmentation, or plasma membrane vesiculation, typical characteristics of apoptosis.

190 GTPases involved in membrane deformation and vesiculation, ubiquitous in Eukaryotes, are also present

191 t the critical membrane size for spontaneous vesiculation was correlated with membrane thickness, and

192 The degree of membrane vesiculation was more than 50% lower in EASs than in Ads

193 f envelope proteins resulting from decreased vesiculation was toxic and contributed to the growth def

194 latory mechanisms and physiological basis of vesiculation, we conducted a screen in Escherichia coli

195 f endoplasmic reticulum (ER) aggregation and vesiculation were observed in BBSV-infected Nicotiana be

196 serves a role similar to that of EHD1 in TRE vesiculation, whereas EHD2, despite being capable of ves

197 EHD1 and EHD4 are primarily in TRE membrane vesiculation, whereas EHD3 is a membrane-tubulating prot

198 EHD1 induces membrane vesiculation, whereas EHD3 supports TRE biogenesis and/o

199 nd cholesterol depletion abrogated C5b-9 exo-vesiculation, whereas, over-expression of Cav-1 increase

200 ned and swollen cisternae, and partial Golgi vesiculation, which are consistent with defects in secre

201 ring is independent of endoplasmic reticulum vesiculation, which occurs only at ionomycin concentrati

202 ion increases both MVB biogenesis and inward vesiculation within EGFR-containing MVBs.

203 s, suggesting that MVB biogenesis and inward vesiculation within MVB are mediated by separate mechani