ライフサイエンスコーパス: villi

1 oth muscle cells encircling arteries in stem villi.

2 then a zigzag pattern, and lastly individual villi.

3 i but did not alter the fraction of perfused villi.

4 l cell shape as well as in the morphology of villi.

5 rding to cell production demands of adjacent villi.

6 ly repopulate multiple contiguous crypts and villi.

7 s clusters and results in exceptionally wide villi.

8 t the crypt base, and by apoptotic events in villi.

9 ped its genome occupancy in adult intestinal villi.

10 the proliferative compartment of intestinal villi.

11 ffusional screening may operate in placental villi.

12 after which macrophages had migrated to the villi.

13 ive RBCs occurs in first trimester placental villi.

14 reduction in Ki67 positive cells and blunted villi.

15 on from the capillary network at the tips of villi.

16 tor to the brush border membrane of duodenal villi.

17 ect underlying cytotrophoblasts in chorionic villi.

18 idence for Wnt signaling after appearance of villi.

19 uction without affecting T cell migration to villi.

20 terstitial cytotrophoblasts in the placental villi.

21 epithelium and lamina propria of the apical villi.

22 17H BChE were in the epithelial cells of the villi.

23 , and markedly lower in the upper portion of villi.

24 layer of the crypts, and Akt2 was mostly in villi.

25 roliferating crypts of Lieberkuhn but not in villi.

26 to round cystic structures without crypts or villi.

27 ltured lymphocytes, amniocytes, or chorionic villi.

28 xtracellular tip-links that connect adjacent villi.

29 last hyperplasia and overgrowth of placental villi.

30 kedly involuted however, most notably in the villi.

31 roduces a dramatic, very unusual widening of villi.

32 lls of the crypts and only marginally in the villi.

33 (CCR5)-positive macrophage-like cells in the villi.

34 al cells in lymph node sinuses and placental villi.

35 y prominent within the lamina propria of the villi.

36 ure of explants of human placental chorionic villi.

37 pts as well as a reduction in the density of villi.

38 villous trophoblasts (EVTs) at the anchoring villi.

39 ia, embryonic hair follicles, and intestinal villi.

40 les and in enterocytes lining the intestinal villi.

41 L-10 was also substantially increased in the villi.

42 served in the interfollicular region and the villi.

43 rincipal driving force for cell migration on villi.

44 zation of CD4+ T cells within the intestinal villi.

45 with the epithelial cells of the intestinal villi.

46 on of mucin filled cysts, and lengthening of villi.

47 d was localized to absorptive enterocytes on villi.

48 nchronized response of cell migration on the villi.

49 l cells, especially in the upper half of the villi.

50 an anatomically correct model of rat jejunal villi.

51 ialized "hotspots" at the distal tips of ChP villi.

52 to crypts and the lower third of intestinal villi.

53 clusters and changes the pattern of emerging villi.

54 rentiated absorptive epithelial cells in the villi.

55 ive higher tissue oxygenation at the base of villi.

56 oes not determine the pattern of clusters or villi.

57 tiated poorly and exhibited severely stunted villi.

58 m cells become restricted to the base of the villi.

59 separation, pulmonary alveoli and intestinal villi.

60 apoptosis and, consequently, loss of nascent villi.

61 rients are absorbed solely by the intestinal villi.

62 ypts and subsequent shrinkages of crypts and villi.

63 erved a more than 8-fold decrease in injured villi (4% vs 34% in saline-pretreated animals).

64 so slightly altered the fraction of perfused villi (94% +/- 2% in hemorrhagic shock group vs 100% +/-

65 nd neutrophil infiltration in the intestinal villi, accompanied by elevated cholesterol but reduced c

66 entiated SynTBs in first-trimester placental villi; accordingly, expression in SynTBs is maintained t

67 neutrophil infiltration into the intestinal villi, administration of D-4F mitigated macrophage infil

68 DraKO and wild-type villi also demonstrated regulation of apical Na(+)/H(+)

69 We detected longer villi, an expanded zone of PCNA expression, and increase

70 maged cells followed by rapid destruction of villi and accelerated lethality.

71 y overlapping, functions in early intestinal villi and adult crypts.

72 from basal and parietal decidua to chorionic villi and amniochorionic membranes and that targeting TI

73 fibroblasts, and Hofbauer cells in chorionic villi and amniotic epithelial cells and trophoblast prog

74 When the cells reach the apex of the villi and are fully differentiated, they undergo cell de

75 roscopy revealed that albumin accumulated in villi and at the base of the brush border.

76 um, active total Akt was present most in the villi and basal layer of the crypts, and Akt2 was mostly

77 An increase in the number of chorionic villi and blood vessels over that in controls suggested

78 ion, and decreased growth of small intestine villi and colon crypts.

79 full aPKC down-regulation in small intestine villi and colon surface epithelium using a conditional e

80 11 alone produced serious damage to duodenal villi and colonic crypts.

81 (-/-)Eat2b(-/-) mice, indicated by flattened villi and crypt hyperplasia.

82 ly modulated epithelial morphologies such as villi and crypts is usually associated with the epitheli

83 prediction and 2D-DIGE/mass spectrometry on villi and crypts samples, we found that ablation of PepT

84 as apoptosis was clearly observed in jejunal villi and crypts, (42 times more M30 positivity compared

85 onfined to crypts and apoptosis occurring in villi and crypts.

86 axis and changed the miRNA profiles of both villi and crypts.

87 ts syncytiotrophoblasts that cover chorionic villi and cytotrophoblasts that invade uterine vessels,

88 ochemistry localized CYP2J2 in trophoblastic villi and deciduas at 12 weeks and term.

89 iated syncytiotrophoblast (STB) in chorionic villi and extravillous trophoblast (EVT) at the implanta

90 s of intestinal luminal spaces, and restored villi and goblet cell morphology.

91 to retain integrity of their small intestine villi and had reduced eosinophilic infiltration as compa

92 bited a 2-fold increase in length of jejunal villi and have normal growth on a normal diet but were l

93 D34(+)CD45(low)-that were found in chorionic villi and in the chorioamniotic membrane.

94 seen in the lamina propria of the intestinal villi and in the liver.

95 ytiotrophoblasts on the surfaces of floating villi and invasive CTBs that remodel the uterine vascula

96 thesis, we exposed first-trimester chorionic villi and isolated cytotrophoblasts to CMV in vitro.

97 n of the absorptive surface of the tube into villi and microvilli.

98 6 mice began dying), massive necrosis of the villi and mucosal cells in the ilea were observed in B6

99 Blunting and fusion of intestinal villi and multifocal infiltration of mononuclear cells w

100 MML from individual villi and numbers of adherent leukocytes within villi we

101 ly seen in folded structures from intestinal villi and pollen grains to wrinkled membranes and progra

102 teria (SFB), a gut microbe residing on ileum villi and PP FAE that mediates resistance to STm infecti

103 entalized intestinal epithelium comprised of villi and terminally differentiated cells.

104 th muscle cells in blood vessels of floating villi and the chorion.

105 n mRNA localized predominantly in intestinal villi and the corticomedullary junction of the kidney, w

106 nd to enterocytes in rat pups at the tips of villi and to intestinal epithelial cells (IEC-6) in cult

107 phoblasts and endothelial cells of chorionic villi and uterine arteries.

108 o establish the characteristics of placental villi and vessels.

109 ube to form finger-like luminal projections (villi) and flask-shaped invaginations (crypts).

110 ce of the normal columnar epithelial lining, villi, and Brunner's glands, which are replaced by a GLU

111 MC appeared in the crypts at the base of the villi, and by wk 2 the number of MC throughout the villi

112 pithelial cells at the tip of the intestinal villi, and colocalized with tyrosine nitration, an index

113 ical degradation, complete denudation of the villi, and crypt injury (especially in the ileum) after

114 sive fibrinoid deposits, fibrosis, avascular villi, and edema, which could impair placental functions

115 a and Firmicutes penetrated small intestinal villi, and flagellated bacteria breached the colonic muc

116 creas, surface colonocytes, small intestinal villi, and gastric isthmus cells.

117 ctural degeneration with the loss of crypts, villi, and glandular structure by 7 days.

118 ll hypertrophy of blood vessels, blunting of villi, and lacteal dilatation with lymphocytes and polym

119 rypts, somewhat less in the lower portion of villi, and markedly lower in the upper portion of villi.

120 ng caloric uptake and increasing intestinal, villi, and microvilli lengths.

121 elial barrier, severe blunting of intestinal villi, and recruitment and activation of myeloid cells.

122 of conventional B cells in small intestinal villi, and suggest an immunologic link between CD1-restr

123 nt at the tips of the villi, the base of the villi, and the submucosa, respectively.

124 e synovial lining and the stroma of synovial villi, and to a lesser extent in CD68-positive cells of

125 vasculatures in endocrine glands, intestinal villi, and uterus are the most affected in response to V

126 flammatory infiltrate in placental chorionic villi are associated with adverse pregnancy results.

127 ithelial cell migration velocities along the villi are coupled to cell proliferation rates within the

128 al intestinal epithelium is stratified, that villi are formed by an epithelial remodeling process inv

129 the numbers of enteroendocrine cells in the villi are greatly reduced.

130 mesenchymal cell clustering beneath emerging villi are implicated in epithelial folding, the underlyi

131 essentially the same way as in mammals: the villi are lined with non-dividing differentiated cells,

132 d laboratory strain AD169 in human placental villi as explants in vitro and xenografts transplanted i

133 nine deficiency blunts mastocytosis in ileal villi as well as bacterial translocation, measured as nu

134 d syncytiotrophoblast derived from placental villi at term and colonies of trophoblast differentiated

135 As and their target proteins along the crypt-villi axis in the jejunum of PepT1 KO mice.

136 rophoblast stem cells in anchoring chorionic villi become invasive.

137 tive erythroid cells were found in placental villi between 5-7 weeks of development, at which time th

138 tion with dramatic atrophy of the intestinal villi, bone marrow, and spleen, and with hematopoietic f

139 ic shock not only decreased RBCs velocity in villi but also slightly altered the fraction of perfused

140 oxemia decreased RBCs velocity in intestinal villi but did not alter the fraction of perfused villi.

141 that the enzyme is expressed not only in the villi, but also in the crypt regions of the small intest

142 li K1 bacteria are physically separated from villi by the mucus layer and their numbers controlled by

143 Capillaries in jejunal villi can absorb nutrients at rates several hundred time

144 ation of stem and progenitor cells along the villi, caused a mild defect in the apical junction orien

145 t global X reactivation is also inducible in villi cells from first-trimester spontaneous abortions b

146 mesenchymal cores of their small intestinal villi, compared with conventionally raised animals that

147 at remodeling of resistance arteries in stem villi contributes to IUGR by compromising umbilical bloo

148 with the earliest steps in the growth of new villi, contributing to virus transmission and impairing

149 Cytotrophoblasts of the anchoring villi convert during human placentation from a transport

150 The morphometric parameters of the villi, crypts, muscular layer and total wall generally i

151 Microfluorimetry of villi demonstrated that Dra is the dominant Cl(-)/HCO(3)

152 tion in a 2D+1D geometry for a wide range of villi densities.

153 The predicted optimal villi density 0.47+/-0.06 is compatible to previous expe

154 The effect of villi density on oxygen transfer efficiency is assessed

155 ters, we observe the existence of an optimal villi density providing a maximal oxygen uptake as a tra

156 additive manner and the fraction of perfused villi dropped in a synergistic manner (69% +/- 3% in hyp

157 th shortening and widening of the intestinal villi due to diffuse edema and infiltration by a mixed i

158 nected vessels developed in small intestinal villi during the period of postnatal development that co

159 hair follicles, limb digits, and intestinal villi, during development.

160 e placenta leads to development of avascular villi, edema, and hypoxia associated with symptomatic co

161 Large fibrinoids with avascular villi, edema, and inflammation were significantly increa

162 explant culture of first-trimester chorionic villi enhanced extravillous trophoblast differentiation

163 we confirmed by analyzing purified placental villi, enriched in endothelium, by immunoblotting with a

164 1-2% of 129/Sv (DeltaN89 beta-catenin) villi exhibited an abnormal branched architecture.

165 During late gestation, villi extend into the intestinal lumen to dramatically i

166 ians, this instability is a precursor of the villi, finger-like projections into the lumen.

167 Villi first emerge at embryonic day (E) 14.5 from a prev

168 tion of the crypts and extreme shortening of villi following 1500 cGy total body irradiation.

169 -lymphocyte population within the intestinal villi following Cryptosporidium parvum infection was cha

170 However, as the villi form, the putative stem cells become restricted to

171 ough enteral losses improve along with graft villi formation, electrolyte abnormalities continue, to

172 cytotrophoblasts in explants, and anchoring villi formed normally in vitro.

173 Isolated small bowel and intestinal villi from alpha-gustducin null mice showed markedly def

174 Isolated small intestine and intestinal villi from gustducin null mice displayed markedly defect

175 gmented digital photomicrographs of terminal villi from the Pregnancy, Infection and Nutrition study

176 activity, are markedly reduced on placental villi from women with this syndrome.

177 resent in the villi, indicating that MUCTag6 villi goblet cells do not progress into M phase.

178 Ag mice expressing large T-antigen solely in villi had ectopic enterocyte proliferation with increase

179 tric foveolar cells, whereas small intestine villi had only a few (<1%) positive cells.

180 ed of crypts harboring Lgr5+ stem cells, and villi harboring differentiated cells.

181 Moreover, the intestinal villi have a steep oxygen gradient from the hypoxic epit

182 ose endings to the apical tips of intestinal villi, immediately subjacent to the epithelial wall.

183 ation process of primitive RBCs in placental villi, implying an unexpectedly broad role for the place

184 al calcification of the maternal surface and villi in a cohort of smokers and nonsmokers at risk for

185 senchymal clusters determines the pattern of villi in a manner that mimics the spread of a self-organ

186 ion as it decreases the fraction of perfused villi in a synergistic manner, thereby increasing the ri

187 ound in the crypts in neonatal and along the villi in adult tissues.

188 ound in epithelial cells of small intestinal villi in all puppies and the colon in 2 of the 10 puppie

189 velopment, but does not prevent emergence of villi in areas where clusters have already formed.

190 nta, FOS was expressed in proximal anchoring villi in conjunction with phospho-ERK.

191 intestine but are present in both crypts and villi in MUCTag6.

192 py confirmed mild shortening and blunting of villi in the duodenum and jejunum of the TC-PEC-inoculat

193 Injury and swelling of the villi in the duodenum was present in untreated mice afte

194 This is analogous to the function of villi in the intestine or sulci in the brain, where an e

195 e and gradually increased towards the apical villi in the small intestinal epithelium.

196 d to the mesenchymal cells at the tip of the villi in the small intestine and directly underlying the

197 anylin mRNA was localized in both crypts and villi in the small intestine and to superficial epitheli

198 ces, including reaching the surfaces between villi in the small intestine.

199 s of N2 or glucose were directed at duodenal villi in vitro, labeling by FM1-43 or FM2-10 was observe

200 phoblasts and reduced formation of anchoring villi in vitro.

201 arious exogenous molecules in the intestinal villi in vivo.

202 s most prevalent near the tips of intestinal villi, in the lamina propria, just basal to epithelial c

203 phoblasts and cytotrophoblasts, in chorionic villi-in clinical cases of congenital infection.

204 and by wk 2 the number of MC throughout the villi increased by approximately 25-fold.

205 number of CD8+ T cells within the intestinal villi increased following a challenge infection.

206 yncytial trophoblast of term human placental villi incubated in vitro with D-[1-3H]galactose ([3H]gal

207 cellular trophoblast of term human placental villi incubated in vitro with tritiated leucine ([3H]leu

208 ling present in the syncytial trophoblast of villi incubated the longest times (4 h+) remained in ass

209 trast, mitotic cells were not present in the villi, indicating that MUCTag6 villi goblet cells do not

210 by histologic analysis of terminal ileum (% villi injured).

211 replaced sodium chloride in contact with the villi, intestinal blood flow decreased to 58.6 +/- 2.8%

212 Bacteria were shed back from intestinal villi into the small intestinal lumen and reinfected the

213 r, foci unexpectedly varied in the number of villi involved and were associated with the presence of

214 re L. monocytogenes replicates in intestinal villi, is shed into the lumen, and reinfects intestinal

215 ls of neutrophil influx and extravasation in villi lamina propriae, including elastase-positive cells

216 uced intestinal damage observed by shortened villi, loss of crypt architecture and intense inflammato

217 15 weeks had a decreased volume of transport villi (mean decrease [standard deviation], 12.45 [5.39]

218 poietic organs, extensive loss of intestinal villi, obstructive enterocolitis, and lethality within 1

219 Arachnoid villi occlude and degenerate.

220 mental distribution of Zn in small intestine villi of mice subjected to a Zn-enriched diet was imaged

221 Villi of mutant mice became stunted, and enterocytes lac

222 Antigens were also seen in chorionic villi of one of the first trimester placentas.

223 A is expressed at high levels only along the villi of the duodenal epithelium, principally if not exc

224 ) is expressed at high levels only along the villi of the duodenal epithelium.

225 asolateral surface of enterocytes lining the villi of the duodenum and jejunum.

226 The villi of the human and chick gut are formed in similar s

227 ished a vital defensive perimeter within the villi of the ileum in the small intestine.

228 T cells (70%) present within the intestinal villi of the infected ileum.

229 al cells on the upper half of the intestinal villi of the jejunum and ileum.

230 squamous epithelium of the stomach, and the villi of the jejunum.

231 ands, uterine decidua, and injured chorionic villi of the placenta, demonstrating both its induction

232 in the syncytiotrophoblasts of the chorionic villi of the rhesus placenta, within villous cytotrophob

233 Basal expression was found in crypts and villi of the small and large intestine, bronchiolar epit

234 d of surface IgM(+) IgD(+) cells residing in villi of the small intestine and superficial lamina prop

235 The villi of the small intestine maintain a hypertonic inter

236 and enteroendocrine cells in both crypts and villi of the small intestine, with no changes observed i

237 o syncytiotrophoblasts in floating chorionic villi or extravillous trophoblasts (EVTs) at the anchori

238 were increased more than fourfold in MUCTag6 villi (P < 0.0001), and apoptotic goblet cells were evid

239 cm(3); P = 0.02) with anisomorphic growth of villi (P = 0.025).

240 ytokine IL-8 (p = 0.0271), longer intestinal villi (p<0.0001), deeper crypts (p = 0.0053), and a thin

241 d toxin A-mediated destruction of intestinal villi, p21(WAF1/CIP1) expression, and enterocyte apoptos

242 es of the kidney and those of the intestinal villi, pancreas, and adrenals.

243 ee within the epithelial cells higher up the villi, paralleling the gradient in expression of the pol

244 In the intestine, finger-like villi provide abundant surface area for nutrient absorpt

245 zed array of finger-like projections, called villi, provide an enormous epithelial surface area for a

246 nated in the liver, whereas small intestinal villi provided a niche for bacterial replication, indica

247 reased villous height, crypt depth, crypt to villi ratio and expression of the proliferation marker,

248 phoblastic lacunae or newly formed chorionic villi remained largely Mamu-AG-negative.

249 fusion can be numerically solved in terminal villi represented by digital photomicrographs.

250 0 (SV40) TAg in choroid plexus or intestinal villi requires at least one activator E2F.

251 eculiar intestinal morphology with very long villi resulting from increased enterocyte lifespan and a

252 osaminoglycans on trophoblasts and chorionic villi, resulting in increased permeability of human plac

253 icroscopic examination of MUCTag6 intestinal villi revealed the presence of degraded cell remnants co

254 dysregulation, and atrophy of the intestinal villi, skin, thymus, and spleen.

255 limited to the epithelium of the developing villi strictly within the duodenal region of the small i

256 enous molecular markers that illustrated the villi structures and confirmed the different absorption

257 In chorionic villi, syncytiotrophoblasts did not become infected, alt

258 In placental villi, syncytiotrophoblasts express the virion receptor

259 e rise to the mature cell types of chorionic villi-syncytiotrophoblasts on the surfaces of floating v

260 Covering the surface of villi that float in blood, syncytiotrophoblasts express

261 med self-regenerating cell clusters, forming villi that resemble intestinal epithelium.

262 In chorionic villi that were infected with CMV in utero, syncytiotrop

263 ng mMCP-2 as they present at the tips of the villi, the base of the villi, and the submucosa, respect

264 hen the epithelium is folded into crypts and villi, the epithelium is a single-cell layer once again.

265 ished physically in the human, the placental villi, the exocoelomic cavity, and the secondary yolk sa

266 ifferentiation during a 48-72-h migration up villi, there is a marked and rapid fall in the levels of

267 ll intestinal crypts to the base of adjacent villi, they rapidly lose their ability to undergo apopto

268 s less heterogeneous than the mucus covering villi tips in the pig model used.

269 phoblasts in vivo by transplanting placental villi to the fifth mammary fat pads or beneath the kidne

270 sign principles to recapitulate native crypt-villi topography and luminal flow, Nikolaev et al.

271 Tubule cell injury, as shown by loss of villi, tubule dilation, and cellular protrusions into th

272 psule endoscopy showed delayed appearance of villi until the proximal to mid jejunum and jejunal muco

273 nding smooth muscle fold the epithelium into villi via mucosal buckling.

274 DNA methylation in first-trimester chorionic villi was assessed in chromosomally normal miscarriages

275 The failure to form villi was not attributable to the absence of HH or PDGF

276 at [3H]gal incorporation into term placental villi was predominantly localized to cytotrophoblast.

277 Absorption of metals in intestinal villi was simulated by means of ultrafiltration over sem

278 n the jejunum, but the percentage of damaged villi was still reduced considerably (18% vs 42%).

279 rs of adherent leukocytes within, individual villi were determined every 15 min for 2 hr after remova

280 li and numbers of adherent leukocytes within villi were determined for 2 to 4 hours after clamp remov

281 er-like structures, similar in appearance to villi were observed.

282 ayed spontaneous duodenal lesions, and ileal villi were truncated and fragile with reduced cellular p

283 in the submucosa and muscle layers, but the villi were unaffected.

284 d apoptosis, specifically at the tips of the villi, where there is highest sheer.

285 out 4 days to migrate out to the tips of the villi, where they die.

286 l epithelial cells throughout the crypts and villi, where we also observed infiltration of activated

287 ACAT-2 is concentrated at the apices of the villi, whereas ACAT-1 is uniformly distributed along the

288 d in the nuclei of superficial layers of the villi, whereas Ki67-positive cells were confined to the

289 , PPARgamma expression occurs throughout the villi, whereas the expression of both SRC-1 and PBP is c

290 mester through term) that contained floating villi (which include cytotrophoblasts differentiating in

291 ing into syncytiotrophoblasts) and anchoring villi (which include cytotrophoblasts differentiating in

292 ne, endothelial, and immune cells; placental villi, which are bathed in maternal blood, and fetal mem

293 is mediated by mesenchymal signaling to form villi, which are required for efficient nutrient absorpt

294 xposure caused remodelling of the intestinal villi, which increased the surface area available for ir

295 in the IFR and lamina propria of intestinal villi, while F4/80+ cells were found only in the latter.

296 overexpressed revealed multiple well-formed villi with crypt-like units, whereas those in which epim

297 n of villous M cells on all small intestinal villi with the capacity for avid uptake of Salmonella an

298 and explants from first-trimester chorionic villi with the prototype Ugandan and a recently isolated

299 1-Fc had significantly deeper crypts, longer villi, with increased EdU labeling, indicating increased

300 xpression at the level of the invasive fetal villi within the placental junctional zone, where tropho