ライフサイエンスコーパス: vitamin K2

1 he siderophore enterobactin and menaquinone (vitamin K2).

2 UBIAD1, a prenyltransferase that synthesizes vitamin K2.

3 anel of bone markers to an extent similar to vitamin K2.

4 10 mg daily, or rivaroxaban 10 mg daily plus vitamin K2 2000 ug thrice weekly during 18 months.

5 nduced by ligature placement for 7 days, and vitamin K2 (30 mg/kg) and/or vitamin D3 (2 mug/kg) were

6 ted step for biosynthesis of menaquinone, or vitamin K2, a key cofactor for electron transport in bac

7 The mechanism of vitamin K2 action in bone formation was thought to invol

8 However, there is evidence that suggests vitamin K2 also has a transcriptional regulatory functio

9 We show that vitamin K2 and lithocholic acid, a by-product of intesti

10 Vitamin K2 and vitamin D3 are known to play important ro

11 d distilled water (Control), vitamin K2 (K), vitamins K2 and D3 (KD), or vitamin D3 (D) for 8 weeks.

12 nt study aimed to investigate the impacts of vitamins K2 and D3 administration on GBR of calvarial cr

13 to investigate the effects of administering vitamins K2 and D3 alone or in combination to restore bo

14 The use of vitamins K2 and D3 as adjuncts to guided bone regenerati

15 Vitamins K2 and D3 exhibit anabolic effects on bone meta

16 RP + vitamin D3, SRP + vitamin K2, and SRP + vitamins K2 and D3 groups by oral gavage.

17 herefore, we conclude that administration of vitamins K2 and D3 improves bone healing in critical-siz

18 The administration of vitamins K2 and D3 in GBR enhanced bone healing in CCSD

19 Previous research revealed that vitamins K2 and D3 supplements might be effective as a t

20 itamin D3; 5) SRP + vitamin K2; and 6) SRP + vitamins K2 and D3.

21 bone defects of rats that received combined vitamins K2 and D3.

22 ylloquinone (vitamin K1) into menaquinone-4 (vitamin K2) and store the latter in tissues.

23 of phylloquinone (vitamin K1), menaquinones (vitamin K2), and dihydrophylloquinone (dihydrovitamin K1

24 d for 10 days in the SRP + vitamin D3, SRP + vitamin K2, and SRP + vitamins K2 and D3 groups by oral

25 titis; 3) SRP; 4) SRP + vitamin D3; 5) SRP + vitamin K2; and 6) SRP + vitamins K2 and D3.

26 Dietary supplements containing vitamin K2 are often used to prevent osteoporosis, vascu

27 systematic review which entirely focuses on Vitamin K2 as a chemo preventive agent is available to d

28 Vitamin K2 bound to and activated the orphan nuclear rec

29 s inhibitors, iron chelators, vitamin E, and vitamin K2 can prevent ferroptosis induced by Gpx4 defic

30 Collectively, these findings reveal that Vitamin K2 could induce metabolic stress and trigger AMP

31 of ubiquinone (coenzyme Q) and menaquinone (vitamin K2), essential isoprenoid quinone components of

32 Phylloquinone (vitamin K1) and menaquinones (vitamin K2 family) are essential for post-translational

33 10 mg rivaroxaban daily, or rivaroxaban and vitamin K2 for 18 months.

34 in any dosage were compared to placebo or No vitamin K2, for participants of any age or sex.

35 0.22 to 1.08; P=0.08) in the rivaroxaban and vitamin K2 group and 0.44 (95% CI, 0.23 to 0.85; P=0.02)

36 up and to a larger extent in the rivaroxaban+vitamin K2 group, but remained nevertheless elevated.

37 19 to 0.61; P=0.0003) in the rivaroxaban and vitamin K2 group, compared with the VKA group.

38 per 100 person-years in the rivaroxaban and vitamin K2 group.

39 Vitamin K2 has been shown to exert remarkable anticancer

40 Vitamin K2 has been tested in trials for its effect on p

41 Withdrawal of VKAs and high-dose vitamin K2 improve vitamin K status in patients on hemod

42 Insufficient information on the content of vitamin K2 in our foods hinder estimation of the dietary

43 rmediate in the biosynthesis of menaquinone (vitamin K2) in both gram-negative and gram-positive bact

44 ession of PI3K/AKT and HIF-1alpha attenuated Vitamin K2-increased glucose consumption and lactate gen

45 enuation of glycolysis significantly blocked Vitamin K2-induced AMPK activation and subsequently prev

46 nthesis of the electron carrier menaquinone (vitamin K2) involves at least seven identified enzymatic

47 Vitamin K2 is a critical nutrient required for blood clo

48 We infer that vitamin K2 is a transcriptional regulator of bone-specif

49 Menaquinone (MK, vitamin K2) is a lipid-soluble molecule that participate

50 ted step in the biosynthesis of menaquinone (vitamin K2) is the conversion of chorismate to isochoris

51 Menaquinone-7 (MK-7), also known as vitamin K2, is a cofactor for the carboxylation of prote

52 and administered distilled water (Control), vitamin K2 (K), vitamins K2 and D3 (KD), or vitamin D3 (

53 Here, we show that UBIAD1, a vitamin K2/menaquinone-4 biosynthetic enzyme, functions

54 vitamers, vitamin K1 (phylloquinone; PK) and vitamin K2 (menaquinones; MK-4 to MK-10) in 88 composite

55 The synergistic effects of vitamin D3 and vitamin K2 on bone loss prevention have been reported.

56 rched for randomized controlled trials where vitamin K2 or its analogues, in any dosage were compared

57 ssigned participants to receive 400 mug oral vitamin K2 or matching placebo once daily for a year.

58 Bacterial enzymes of the menaquinone (Vitamin K2) pathway are potential drug targets because t

59 mpared with controls, participants receiving Vitamin K2, pooled relative risks for hepatocellular can

60 tion and lactate generation, indicating that Vitamin K2 promotes PI3K/AKT and HIF-1alpha-mediated gly

61 Here, our study was the first to show that Vitamin K2 significantly promoted the glycolysis in blad

62 Vitamin K2 supplementation did not improve vascular stif

63 tudy evaluates the effects of vitamin D3 and vitamin K2 supplementation in conjunction with conventio

64 Vitamin K2 supplementation up-regulates the expression o

65 eveal an essential role for UBIAD1-generated vitamin K2 to maintain endothelial cell survival and ove

66 Vitamin K2 treatment of osteosarcoma cells increased mRN

67 vation and rescued bladder cancer cells from Vitamin K2-triggered autophagic cell death.

68 Importantly, upon glucose limitation, Vitamin K2-upregulated glycolysis markedly induced metab

69 groups administered either distilled water, vitamin K2, vitamin D3 or both.

70 Vitamin K2 was able to induce bone markers in primary os

71 ylgeranyl pyrophosphate (GGpp) to synthesize vitamin K2 We previously reported that sterols stimulate

72 Furthermore, we have discovered that vitamin K2, which is synthesized by UBIAD1, can also res