ライフサイエンスコーパス: voltage-gated

1 ntial, and they are generally not considered voltage gated.

2 nto giant unilamellar vesicles (GUVs), forms voltage-gated and Ca(2+)-activated channels with the key

3 By redistributing voltage-gated and returning transmembrane currents in th

4 s to the microenvironment of the presynaptic voltage gated Ca(2+) channels revealed that alkalinizati

5 rtensives, function by inhibiting the L-type voltage-gated Ca(2+) (Ca(v) ) channels.

6 al information processing units that rely on voltage-gated Ca(2+) (Ca(v)) channels to trigger Ca(2+)-

7 ta also indicate that a cardiomyocyte L-type voltage-gated Ca(2+) channel (Ca(v)) subunit (alpha2delt

8 ts, but the circadian regulation of distinct voltage-gated Ca(2+) channel (VGCC) components has not b

9 ence exists for the pharmacoresistant R-type voltage-gated Ca(2+) channel (VGCC) to be involved in tr

10 syndactyly, highlighted roles for the L-type voltage-gated Ca(2+) channel Ca(V)1.2 in nonexcitable ce

11 effect on the regulation of the plasmalemmal voltage-gated Ca(2+) channel, Ca(v)1.2.

12 tions using fluorometric assays, and blocked voltage-gated Ca(2+) channels (Ca(V)) as a downstream me

13 +)](i)) that is due to Ca(2+) influx through voltage-gated Ca(2+) channels (VGCC) and plasma membrane

14 and animal models had suggested that several voltage-gated Ca(2+) channels (VGCCs) regulated critical

15 In previous studies, T-type voltage-gated Ca(2+) channels (VGCCs) were implicated in

16 tivated G proteins decreases the activity of voltage-gated Ca(2+) channels (VGCCs), decreasing excita

17 ed with a climbing fiber (CF) EPSP activates voltage-gated Ca(2+) channels (VGCCs), voltage-gated K(+

18 Ry-sensitive Ca(2+) store refilling involves voltage-gated Ca(2+) channels (VGCCs).

19 ugh Ca(2+) influx, via Ca(V)1.2, 1 of L-type voltage-gated Ca(2+) channels (VGCCs).

20 To determine whether Cav1.2 voltage-gated Ca(2+) channels contribute to astrocyte ac

21 veral studies have suggested that opening of voltage-gated Ca(2+) channels near resting membrane pote

22 Voltage-gated Ca(2+) channels play a pivotal role in thi

23 hs in our understanding of the properties of voltage-gated Ca(2+) channels that support their presyna

24 th an overall increased expression of L-type voltage-gated Ca(2+) channels that, at presynaptic termi

25 n of fusion-competent synaptic vesicles near voltage-gated Ca(2+) channels.

26 entified that regulate SCN firing, including voltage-gated Ca(2+) currents, but the circadian regulat

27 ing diseases.SIGNIFICANCE STATEMENT Reducing voltage-gated Ca(2+) influx in astrocytes during brain d

28 lination; and that attenuation of astrocytic voltage-gated Ca(2+) influx may be an effective therapy

29 Voltage-gated Ca(v)1 and Ca(v)2 Ca(2+) channels are comp

30 e mutation that leads to gain-of-function of voltage-gated Ca(V)2.1 Ca(2+) channels and high risk for

31 Calcium homeostasis modulators (CALHMs) are voltage-gated, Ca(2+)-inhibited nonselective ion channel

32 , there is a dose-dependent effect of L-type voltage gated calcium channel inhibitors on synchronous

33 Among the ten subtypes of mammalian voltage-gated calcium (Ca(v)) channels, Ca(v)3.1-Ca(v)3.

34 Calmodulin (CaM) regulation of voltage-gated calcium (Ca(V)1-2) channels is a powerful

35 L-type voltage-gated calcium (Cav1) channels have a key role in

36 report the presence of a splice isoform of a voltage-gated calcium channel (Ca(V)1.3) in the pigeon i

37 rom Nematostella vectensis use a specialized voltage-gated calcium channel (nCa(V)) to distinguish sa

38 Genetic polymorphisms of the L-type voltage-gated calcium channel (VGCC) are associated with

39 bicistronic expression may be common to the voltage-gated calcium channel (VGCC) gene family and may

40 study the effect of LITAF on Cav1.2 (L-type voltage-gated calcium channel 1.2) channel expression, s

41 ies in the serum (21.30 nmol/L) and P/Q-type voltage-gated calcium channel antibodies (220 pmol/L).

42 is a psychiatric risk gene that encodes the voltage-gated calcium channel Ca(V)1.2.

43 ll biology in bystander neurons, as were the voltage-gated calcium channel Cacophony (Cac) and the mi

44 show that FMRP binds the mRNA of the R-type voltage-gated calcium channel Cav2.3 in mouse brain syna

45 iomyocytes demonstrated that the anti-L-type voltage-gated calcium channel immunoglobulin G purified

46 In contrast, blocking the T-type or L-type voltage-gated calcium channel promoted the spontaneous c

47 tibody against the pore domain of the L-type voltage-gated calcium channel was consistently identifie

48 cooperation with the orthologue of an R-type voltage-gated calcium channel.

49 ggests that BsYetJ/TMBIM6 is a pH-dependent, voltage-gated calcium channel.

50 tors juxtaposed with presynaptic ribbons and voltage-gated calcium channels (Ca(V)1.3).

51 y, we found that BIN1 interacted with L-type voltage-gated calcium channels (LVGCCs) and that BIN1-LV

52 ar calcium involves purinergic receptors and voltage-gated calcium channels (VGCC).

53 ACh release is supported by P/Q- and N-type voltage-gated calcium channels (VGCCs) and negatively re

54 For example, presynaptic voltage-gated calcium channels (VGCCs) and postsynaptic

55 that pharmacological manipulation of L-type voltage-gated calcium channels (VGCCs) and purinoceptors

56 Here, we show that voltage-gated calcium channels (VGCCs) are critical for

57 ade of NMDA-type glutamate receptors but not voltage-gated calcium channels (VGCCs), and can also be

58 ulation were mediated, in part, by dendritic voltage-gated calcium channels (VGCCs): pharmacological

59 n of all deletions in the significant set of voltage-gated calcium channels among CNVs called from bo

60 ential (AP) waveform controls the opening of voltage-gated calcium channels and contributes to the dr

61 Deconditioning was mediated by L-type voltage-gated calcium channels and is consistent with co

62 The alpha(2)delta-1 subunit of voltage-gated calcium channels binds to gabapentin and p

63 We have studied the regulation of voltage-gated calcium channels by MDIMP, which disrupts

64 of known renal autoregulation mechanisms and voltage-gated calcium channels can maintain overall rena

65 (2020) demonstrate that Ca(v)2-type voltage-gated calcium channels do not mediate presynapti

66 The dominant role of Ca(V)2 voltage-gated calcium channels for driving neurotransmit

67 e, we found that the alpha2delta2 subunit of voltage-gated calcium channels negatively regulates axon

68 Presynaptic alpha(2)delta subunits of voltage-gated calcium channels regulate channel abundanc

69 psychiatric disorders.SIGNIFICANCE STATEMENT Voltage-gated calcium channels regulate important neuron

70 hibition: first, the action of Gbetagamma on voltage-gated calcium channels to inhibit calcium influx

71 by beta-adrenergic augmentation of Ca(V)1.2 voltage-gated calcium channels(1-4).

72 ponses in each compartment were dependent on voltage-gated calcium channels, and somatic and nuclear

73 glycosylation including glutamate receptors, voltage-gated calcium channels, the dopamine D2 receptor

74 r Ca(2+) levels due to Ca(2+) influx through voltage-gated calcium channels.

75 tial segment was only partially dependent on voltage-gated calcium channels.

76 nism that confers adrenergic modulation upon voltage-gated calcium channels.

77 by which beta-adrenergic agonists stimulate voltage-gated calcium channels.

78 utoregulatory mechanism in Ca(V)1 and Ca(V)2 voltage-gated calcium channels.

79 hanisms and enter the cytosol mostly through voltage-gated calcium channels.

80 changes that led to abnormal inactivation of voltage-gated calcium channels.

81 Voltage-gated calcium currents were unchanged between th

82 ential physiological relevance in control of voltage-gated calcium influx and calcium-dependent cellu

83 d cyclic nucleotide-gated (HCN) channel is a voltage-gated cation channel that mediates neuronal and

84 Hence, the mechanism by which voltage-gated cation channels couple conformational chan

85 ependent on the presence of apically located voltage-gated cation channels in a population of electro

86 ations in the Na(V)1.5-encoding gene, sodium voltage-gated channel alpha subunit 5 (SCN5A), often cau

87 urally metastable protein possesses superior voltage-gated channel regulation, efficient mitochondria

88 Gene expression of KCNA5 (potassium voltage-gated channel subfamily A member 5; encoding Kv1

89 voltage-gated K(+) channel Kv2.1 (potassium voltage-gated channel subfamily B member 1 or KCNB1).

90 The Kv1.3 accessory protein, potassium voltage-gated channel subfamily E (KCNE) subunit 4, acts

91 hat Hip14 palmitoylates the Shaker-like K(+) voltage-gated channel subunit (Kv1.1), thereby regulatin

92 Besides polycystin channels voltage gated channels like HCN4 and KCNQ1 have been imp

93 The evolution of Na(+)-selective four-domain voltage-gated channels (4D-Na(v)s) in animals allowed ra

94 acteria encode single-domain Na(+)-selective voltage-gated channels (BacNa(v)), they typically exhibi

95 nflux depends on the AP waveform dictated by voltage-gated channels and temperature.

96 ons, amplification and impulse generation by voltage-gated channels are dispensable.

97 rom ATP-dependent pumping of Ca(2+) entering voltage-gated channels at the synaptic terminal.

98 ) ion channels, focusing on KcsA and several voltage-gated channels from the K(V) and Na(V) families,

99 In S4-based voltage sensors voltage-gated channels, a common feature is shared; the

100 nels producing the generation potentials and voltage-gated channels, translating the generation poten

101 age sensor movements are not the same in all voltage-gated channels.

102 logous to the S4-S5 linker of domain-swapped voltage-gated channels.

103 CLC-2 is a voltage-gated chloride channel that is widely expressed

104 an cytomegalovirus (HCMV) and identified the voltage-gated chloride ion channel inhibitor 4,4'-diisot

105 This voltage-gated conductance increases neuronal gain and se

106 y and visual stimulation reveal an intrinsic voltage-gated conductance that profoundly alters the int

107 me course of responses to glutamate, but the voltage-gated current profiles of BCs displayed only min

108 ements of mammalian cone light responses and voltage-gated currents to calculate cone ATP utilization

109 ed by mutations in the CLCN5 gene encoding a voltage-gated electrogenic nCl(-)/H(+) exchanger ClC-5.

110 Here, we employ voltage-gated fluorometry to characterize conformational

111 many two-pore domain K(+) (K(2P)) channels, voltage-gated hERG (human ether-a-go-go-related gene) ch

112 clude that RFFL is an important regulator of voltage-gated hERG potassium channel activity and theref

113 The voltage-gated Hv1 proton channel is a ubiquitous membran

114 igm, placing it squarely in the framework of voltage-gated ion channel (VGIC) superfamily members in

115 onal models may have the possibility to link voltage-gated ion channel activation to perception thres

116 The results support the hypothesis that voltage-gated ion channel distributions and morphology d

117 -gated proton channel Hv1 is a member of the voltage-gated ion channel superfamily, which stands out

118 Voltage-gated ion channels (VGICs) contain positively ch

119 proteins are affected as well, particularly voltage-gated ion channels (VGICs).

120 The opening and closing of voltage-gated ion channels are regulated by voltage sens

121 st commonly used pharmacological blockers of voltage-gated ion channels are well understood; however,

122 Voltage-gated ion channels endow membranes with excitabi

123 Voltage-gated ion channels feature voltage sensor domain

124 STATEMENT Changes in dendritic function, and voltage-gated ion channels in particular, are increasing

125 nalogues vary in their selectivity for human voltage-gated ion channels involved in the ventricular a

126 Conductance in voltage-gated ion channels is regulated by membrane volt

127 Voltage-gated ion channels play important roles in physi

128 The distinct ensembles of voltage-gated ion channels predicted to underlie the uni

129 ry and inhibitory cell types, genes encoding voltage-gated ion channels responsible for depolarizing

130 from the aberrant expression and activity of voltage-gated ion channels, although the identification

131 e relationship among gating modifier toxins, voltage-gated ion channels, and the lipid membrane surro

132 In contrast to most voltage-gated ion channels, hyperpolarization- and cAMP

133 tricular action potential depends on several voltage-gated ion channels, including Na(V), Ca(V), and

134 P2 borrows a biophysical riff from canonical voltage-gated ion channels, using 2 gating charges found

135 FXS field has thus far focused primarily on voltage-gated ion channels, while contributions from vol

136 y to regulate the expression and activity of voltage-gated ion channels.

137 much less is known about non-domain-swapped voltage-gated ion channels.

138 nsmitter receptors to the dynamics shaped by voltage-gated ion channels.

139 tics for LQTS because they are modulators of voltage-gated ion channels.

140 The axon models included a wide range of voltage-gated ion channels: Na(TTXs), Na(TTXr), Na(p), K

141 repolarizing K(+) current (I(K)) carried by voltage gated K(+) (K(v)1.5) channels were reduced.

142 HCN channels belong to the family of voltage-gated K(+) (Kv) channels.

143 membrane containing the vectorially oriented voltage-gated K(+) channel for the activated, open and d

144 ovo missense variant in KCNA2, which encodes voltage-gated K(+) channel K(V) 1.2.

145 d functional interaction between DAT and the voltage-gated K(+) channel Kv2.1 (potassium voltage-gate

146 The voltage-gated K(+) channel Kv2.1 serves a major structur

147 these single membranes were dominated by the voltage-gated K(+) channel protein because of the high i

148 on that directly predicted the response of a voltage-gated K(+) channel within a phospholipid bilayer

149 vates voltage-gated Ca(2+) channels (VGCCs), voltage-gated K(+) channels (VGKCs), and Ca(2+)-activate

150 The EAG (ether-a-go-go) family of voltage-gated K(+) channels are important regulators of

151 Voltage-gated K(+) channels function in macromolecular c

152 eactivated, closed states of three different voltage-gated K(+) channels in hydrated phospholipid bil

153 Ca(2+)- and voltage-gated K(+) channels of large conductance (BK cha

154 ity filter landscape in a mutant that mimics voltage-gated K(+) channels, which provides a foundation

155 tide from the Leiurus scorpion venom, blocks voltage-gated K(+)-channels in a unique example of bindi

156 as previously been discovered to block human voltage-gated KCNQ K(+) channels with a 2.5 muM K(d).

157 dicate that induced autoimmunity against the voltage-gated KCNQ1 K(+) channels accelerates cardiac re

158 The function of the voltage-gated KCNQ1 potassium channel is regulated by co

159 e for a key role for low-threshold activated voltage gated L-type Ca(2+) channels in Abeta-mediated n

160 Voltage-gated L-type Ca(2+) channel (Ca(v)1.2) blockers

161 ls (NFAT) depends upon Ca(2+) influx through voltage-gated L-type calcium channels (LTCC) and NFAT tr

162 ciation with reduced expression of SCN5a and voltage gated Na(+) (Na(V)1.5) channels as well as a shi

163 The voltage-gated Na(+) (Na(v)) channel is the molecular det

164 Voltage-gated Na(+) (Na(V)) channels regulate homeostasi

165 Multiple voltage-gated Na(+) (Nav) channelopathies can be ascribe

166 ability is mediated by excessive activity of voltage-gated Na(+) and Ca(2+) channels that is initiall

167 Modification of voltage-gated Na(+) channel (Na(V) ) function by intrace

168 Skeletal muscle voltage-gated Na(+) channel (Na(V)1.4) activity is subje

169 nction, resembling prokaryote single-domain, voltage-gated Na(+) channels (BacNa(v)s) [4].

170 oincident signals depends on the presence of voltage-gated Na(+) channels in the spine head, while NM

171 (2+) entry because of synaptic activation of voltage-gated Na(+) channels within the spine.

172 ors, including the NMDA receptor (NMDAR) and voltage-gated Na(+) channels.

173 ated by an influx of sodium (Na(+)) ions via voltage-gated Na(+) channels.

174 n of diatom EukCatAs indicates that they are voltage-gated Na(+)- and Ca(2+)-permeable channels, with

175 can trigger postsynaptic local activation of voltage-gated Na(+)-channels (Na(v)s), that is a spine s

176 that eliminated the onset response by moving voltage-gated Na+ channels (VGSCs) to closed-state inact

177 f the persistent and resurgent components of voltage-gated Na+ currents in modulating the burst disch

178 ation and two currents that provide dynamic, voltage-gated, negative feedback in subthreshold voltage

179 ha-cells is tightly linked to the opening of voltage-gated P/Q-type Ca(2+) channels, the activation o

180 Here, we identify a family of voltage-gated "pacemaker" channels, HCNL1, that are exqu

181 med mode of action is via blockade of axonal voltage gated potassium channels, thereby enhancing cond

182 Voltage-gated potassium (K(+)) channel subfamily B membe

183 The KCNE2 single transmembrane-spanning voltage-gated potassium (K(v)) channel beta subunit is u

184 After opening, the Shaker voltage-gated potassium (K(V)) channel rapidly inactivat

185 Voltage-gated potassium (K(v)) channels coordinate elect

186 In voltage-gated potassium (K(V)) channels, the voltage-sen

187 gene encoding KCNE5, an ancillary subunit to voltage-gated potassium (K(V)) channels.

188 Voltage-gated potassium (Kv) channels display several ty

189 Voltage-gated potassium (Kv) channels of the Kv4 subfami

190 The electrically silent (KvS) members of the voltage-gated potassium (Kv) subfamilies Kv5, Kv6, Kv8,

191 ssociation of plasma membrane (PM)-localized voltage-gated potassium (Kv2) channels with endoplasmic

192 Voltage-gated potassium 11.1 (K(v)11.1) channels play a

193 ociated with antibodies to components of the voltage-gated potassium channel complex (VGKCC-Ab-LE) of

194 ity, consistent with increased expression of voltage-gated potassium channel gene Kcna1 and decreased

195 eptor channel P2X purinoceptor 7 (P2X7), the voltage-gated potassium channel K(V)1.3 and the voltage-

196 The voltage-gated potassium channel Kv1.5 plays important ro

197 e the measurement of the potency of block of voltage-gated potassium channel subtype 11.1 (K(v)11.1)

198 ree-dimensional structure of the human KCNQ1 voltage-gated potassium channel VSD in the intermediate

199 tion were linked to faster inactivation of a voltage-gated potassium channel, K(v)1.4.

200 re, we demonstrated that microglial Kv1.3, a voltage-gated potassium channel, was transcriptionally u

201 Aminopyridine (4AP) is a specific blocker of voltage-gated potassium channels (K(V)1 family) clinical

202 Voltage-gated potassium channels (K(v)s) are gated by tr

203 Neuronal voltage-gated potassium channels (Kv) are critical regul

204 In voltage-gated potassium channels (VGKC), voltage sensors

205 ty of the VLS, we analyzed the expression of voltage-gated potassium channels in rodent and primate b

206 hairpinin scaffold, which selectively blocks voltage-gated potassium channels K(v)1.3.

207 Kv3 voltage-gated potassium channels mediate action potentia

208 We show that currents mediated by the voltage-gated potassium channels Shaw (Kv3) and Shal (Kv

209 s demonstrated for a photochromic blocker of voltage-gated potassium channels, termed CAL, and a phot

210 However, in several voltage-gated potassium channels, using specific S4-S5(L

211 ee of the four derivatives are able to block voltage-gated potassium channels.

212 ikely because maturing VGNs also acquire low-voltage-gated potassium currents (I (KL)), whose inhibit

213 s inversely correlated to the density of low-voltage-gated potassium currents (I (KL)).

214 n vitro application of ALD increased outward voltage-gated potassium currents significantly, and simu

215 A, receptor activation include regulation of voltage-gated potassium currents.

216 itable membranes using the dynamic clamp and voltage-gated potassium ionic channels (Kv1.3) expressed

217 In addition, we examined the role of the voltage-gated potassium Kv4.2 subunit, a molecular deter

218 appeared self-inhibitory because of ClC-5's voltage-gated properties, but shunt conductance facilita

219 The voltage-gated proton channel Hv1 is a member of the volt

220 The voltage-gated proton channel Hv1 regulates proton fluxes

221 Hv1 is a voltage-gated proton channel whose main function is to f

222 Voltage-gated proton channels (H(V)1) are essential for

223 These results highlight a novel role for the voltage-gated resurgent Na+ component in moderating the

224 conductance, Na-activated K channels (Slo2), voltage-gated (SCN) Na(+) and Na(+) leak channels, nonse

225 ivation of the large-conductance Ca(2+)- and voltage-gated (Slo1) big potassium (BK) channel.

226 variants in the gene SCN1A which encodes the voltage gated sodium (Na(+)) channel subunit Nav1.1.

227 The sarcolemmal voltage gated sodium channel Na(V)1.4 conducts the key d

228 Voltage gated sodium channels are key players in aberran

229 Voltage-gated sodium (Na(V)) and calcium channels (Ca(V)

230 )](i) changes were sensitive to the specific voltage-gated sodium (Na(V)) channel blocker tetrodotoxi

231 We tagged the sole voltage-gated sodium (Na(V)) channel in the fly, para, a

232 Voltage-gated sodium (Na(V)) channels are a functional h

233 Voltage-gated sodium (Na(V)) channels are pore-forming t

234 a granulosa) use tetrodotoxin (TTX) to block voltage-gated sodium (Na(v)) channels as a chemical defe

235 Voltage-gated sodium (Na(V)) channels drive neuronal exc

236 Nonselective antagonists of voltage-gated sodium (Na(V)) channels have been long use

237 s) are intracellular proteins which regulate voltage-gated sodium (Na(v)) channels in the brain and o

238 Voltage-gated sodium (Na(V)) channels initiate action po

239 s pain in mice by inhibiting inactivation of voltage-gated sodium (Na(V)) channels involved in nocice

240 Fast inactivation of voltage-gated sodium (Na(v)) channels is essential for e

241 Voltage-gated sodium (Nav) channels are targets of disea

242 o describe ion conduction and selectivity in voltage-gated sodium and acid-sensing ion channels.

243 tified RBFOX2(40)-driven splicing defects in voltage-gated sodium and potassium channels, which alter

244 ity, as the consequence of the properties of voltage-gated sodium and potassium channels.

245 A biophysical analysis revealed voltage-gated sodium channel (Na(V)) currents in menthol

246 Voltage-gated sodium channel (VGSC) beta1 subunits are m

247 ecent genetic studies have linked pathogenic voltage-gated sodium channel (VGSC) variants to human pa

248 also found alterations in the properties of voltage-gated sodium channel currents in Jedi-1 null neu

249 Missense variants in the SCN8A voltage-gated sodium channel gene are linked to early-in

250 A SIGNIFICANCE STATEMENT Na(v)1.6 is a major voltage-gated sodium channel in human brain, where it re

251 f variants in SCN5A, which encodes the major voltage-gated sodium channel in the heart.

252 Na(v)1.6 (SCN8A) is a major voltage-gated sodium channel in the mammalian CNS, and i

253 The voltage-gated sodium channel is critical for cardiomyocy

254 Nav1.6 is the primary voltage-gated sodium channel isoform expressed in mature

255 The voltage-gated sodium channel isoform Na(V)1.7 is highly

256 The finding of voltage-gated sodium channel mutations in small fibre ne

257 sufficiency of the SCN1A gene encoding brain voltage-gated sodium channel Na(V)1.1.

258 Mutations in the gene encoding the cardiac voltage-gated sodium channel Na(v)1.5 cause various card

259 Voltage-gated sodium channel Na(v)1.5 generates cardiac

260 tage-gated potassium channel K(V)1.3 and the voltage-gated sodium channel Na(V)1.7 as examples of tar

261 Voltage-gated sodium channel Na(V)1.7 is a genetically v

262 In humans, functional loss of the voltage-gated sodium channel Na(v)1.7 leads to pain inse

263 ansient receptor potential channel TRPA1 and voltage-gated sodium channel Na(v)1.7, that accompany al

264 SCN9A encodes the voltage-gated sodium channel Na(v)1.7, which is present

265 monstrates that two disease mutations in the voltage-gated sodium channel Na(v)1.8 that induce nocice

266 We investigated the effect of LITAF on the voltage-gated sodium channel Nav1.5, which is critical f

267 Gain-of-function mutations of voltage-gated sodium channel Nav1.7 underlie dorsal root

268 ies have confirmed an important role for the voltage-gated sodium channel Nav1.9 in human pain disord

269 ilayer affinity and in vitro activity at the voltage-gated sodium channel subtype 1.7 (Na(V)1.7), a c

270 f the interactions between CBD and the NavMs voltage-gated sodium channel, and electrophysiology to s

271 The human voltage-gated sodium channel, hNa(V)1.5, is responsible

272 We determined the structure of a voltage-gated sodium channel, two-pore channel 3 (TPC3),

273 Peripheral sensory neurons express multiple voltage-gated sodium channels (Na(V) ) critical for the

274 trodotoxin (TTX), a neurotoxin that binds to voltage-gated sodium channels (Na(v) proteins), arrestin

275 Voltage-gated sodium channels (Na(V)) are indispensable

276 Voltage-gated sodium channels (Na(v)s) initiate the acti

277 and whether human SAN excitability requires voltage-gated sodium channels (Nav) remains controversia

278 Mutations in voltage-gated sodium channels (Navs) can cause alteratio

279 Voltage-gated sodium channels (VGSC) are transmembrane p

280 We hypothesize that the voltage-gated sodium channels (VGSC) on the dorsal root

281 Notably, voltage-gated sodium channels (VGSC) that are crucial fo

282 Voltage-gated sodium channels are critical for periphera

283 ate, we provide novel evidence that multiple voltage-gated sodium channels are involved in schizophre

284 In this study, we investigated whether voltage-gated sodium channels are involved in the develo

285 Voltage-gated sodium channels are subjected to S-palmito

286 Voltage-gated sodium channels are targets for a range of

287 Voltage-gated sodium channels comprise an ion-selective

288 Na(v)1.7 and other voltage-gated sodium channels in mouse DRG are considere

289 Voltage-gated sodium channels initiate electrical signal

290 Voltage-gated sodium channels play a critical role in ce

291 of organic cation selectivity of eukaryotic voltage-gated sodium channels showed a sharp size cut-of

292 now linked multiple human pain disorders to voltage-gated sodium channels, including disorders chara

293 at, while VPA is capable of binding to these voltage-gated sodium channels, it has a very different m

294 increase in the density of Nav1.5-generated voltage-gated sodium current I (Na) and Nav1.5 surface p

295 was replicated in a computational model when voltage-gated sodium currents were impaired in basket ce

296 Voltage-gated sodium ion channel subtype 1.7 (Na(V)1.7)

297 Voltage-gated T-type Ca(2+) (Ca(V)3) channels regulate d

298 -related genes, as well as genes specific to voltage-gated transmembrane ion transporters.

299 Inwardly rectifying, voltage-gated, two-pore domain, and related K(+) channel

300 of warfarin-like compounds that open the two voltage-gated type 1 potassium (K(V)1) channels K(V)1.5