ライフサイエンスコーパス: well-defined

1 nd ERK2) in cancer progression have not been well defined.

2 buting to these distinct checkpoints are not well defined.

3 g-term trajectory of cortical atrophy is not well defined.

4 the regulatory mechanisms of PrimPol are not well defined.

5 lation (AF) after noncardiac surgery are not well defined.

6 hough how this is accomplished is not always well defined.

7 secondary growth and wood formation are not well defined.

8 for severe COVID-19 infection have not been well defined.

9 lecular triggers and/or facilitators are not well defined.

10 control lymphocyte development has not been well defined.

11 rosthetic joint infection (PJI) has not been well defined.

12 ularly torsades de pointes, risk factors are well defined.

13 ody response to SARS-CoV-2 infection are not well defined.

14 to cardiac symptoms or comorbidities are not well defined.

15 s that mediate their escape behavior are not well defined.

16 ections and intrauterine transmission is not well defined.

17 ose risk of developing gastric cancer is not well defined.

18 and the risk of recurrence over time are not well defined.

19 iratory compromise at delivery have not been well defined.

20 ut the underlying molecular mechanism is not well defined.

21 to accelerated liver fibrosis have not been well defined.

22 ptimal timing of their administration is not well defined.

23 mogenesis, the critical determinants are not well defined.

24 sed to alleviate NPC assembly stress are not well defined.

25 is difficult and the role of genetics is not well defined.

26 ation of serum IgA effector functions is not well defined.

27 associated clinical characteristics are not well defined.

28 in people with a Fontan circulation are not well defined.

29 ial cancer cells during hypoxia remains less well defined.

30 ells beyond antibody-producing cells is less well defined.

31 ing properties and molecular targets are not well defined.

32 atched unrelated donor (mMUD) setting is not well defined.

33 erity of RSV disease in adults have not been well defined.

34 changes in circulating immune cells are less well defined.

35 ral pore, and the NTD-CTD linker region, are well defined.

36 drive cutaneous inflammation in SLE are not well defined.

37 f CD103 and CD49a on this population are not well defined.

38 utations and tumor development have not been well defined.

39 However, the basis of this resistance is not well defined.

40 modifiers in different cancer types are not well defined.

41 mal excitability at the tissue level are not well defined.

42 tions, yet the underlying mechanisms are not well defined.

43 op diuretic, but this combined effect is not well-defined.

44 l brimonidine administration is rare and not well-defined.

45 whole-cell pertussis (wP) vaccination is not well-defined.

46 curacy of these tests, however, has not been well-defined.

47 olecular details of this interaction are not well-defined.

48 aluate sarcomeric architecture have not been well-defined.

49 An atomically well-defined (111) heterointerface between the fluorite

50 , we quantify dendritic cell migration under well-defined 2-dimensional confinement and in a 3-dimens

51 al mechanisms of cancer cell destruction are well defined(3-5), but whether immune-mediated cancer ce

52 ordered regions (IDRs) that do not fold into well-defined 3D structures yet perform numerous biologic

53 Well-defined acetoxy telechelic structures were obtained

54 h addition of LiBr are critical to producing well-defined acrylate polymers with dispersities as low

55 n solution, revealing that Bvht lncRNA has a well-defined, albeit flexible 3-D structure that is remo

56 PVP with well-defined aldehyde and hydroxyl end groups lead to th

57 r of the tricyclic framework from sterically well-defined alpha-aminonitrile 2.

58 Resistance profiles are not well defined among individuals on failing second-line an

59 This ROPISA process affords well-defined amphiphilic diblock copolymers that simulta

60 function, basic insight into the assembly of well-defined amphiphilic polymers to form functional str

61 In vitro analysis of macrophage response to well-defined amyloid-beta1-42 conformers (fibrils, prion

62 In such networks, the longest path is well defined and in some cases is known to be a better a

63 However, this is not well defined and it is unknown if exercise timing induce

64 isms regulating this complex process are not well defined and their understanding could offer potenti

65 serotonergic raphe subgroups in fish are not well defined and therefore remain problematic for cross-

66 fficacy, as social rewards tend to depend on well-defined and highly observable behaviours.

67 Despite the well-defined and nonoverlapping functional properties of

68 thus described constitutes a mechanistically well-defined and operationally robust main-group complem

69 A well-defined and readily available air-stable dimeric ir

70 and misincorporation errors, thus achieving well-defined and resolved di- or tri-BCPs of acrylates.

71 ical analysis led to the identification of a well-defined and significant cluster corresponding close

72 ungus Saccharomyces cerevisiae (ScCdc14) are well-defined and unique among characterized phosphatases

73 cted inflammatory bowel disease (IBD) is not well defined, and its correlation with clinical outcome

74 be important for treating common conditions, well-defined, and impactful (i.e. well-recognized clinic

75 ovalent organic frameworks (COFs) could have well-defined arrangements of photo- and electro-active u

76 The limit of detection (LOD, S/N = 3) is well defined as 4.7 x 10(-8) mol L(-1).

77 We also use this array of well-defined atomically thin MoSe(2) deposits to study p

78 ix, where they self-assemble into fibrils of well-defined axial striped patterns.

79 content of the infectious viral cores is not well defined because methods for directly labeling and q

80 ated with the opioid epidemic are relatively well defined, because passive surveillance systems for t

81 structure shows that the compound binds to a well-defined binding site in RalA as a result of a switc

82 for prototypic GPCRs, most GPCRs still lack well-defined biological ligands and drugs.

83 dispersity remained unaffected, showing that well-defined block co-oligomers can be achieved.

84 The ability to synthesize well-defined block copolymers (BCPs) from one-pot comono

85 this approach is exemplified by synthesis of well-defined block copolymers with distinct branching ch

86 Such control might benefit from a well-defined bond directionality, the ability to designa

87 ovoid and heterogeneous lesions with mostly well-defined borders.

88 Well-defined bottlebrush polymers with rubbery poly(4-me

89 temporal components that can be mapped onto well-defined brain regions.

90 cile and efficient approach for synthesizing well-defined branched poly(monothiocarbonate)s in a "gra

91 Proteins are usually studied in well-defined buffer conditions, which differ substantial

92 ructures with incommensurate arrangements of well-defined building blocks using a synthetic approach

93 ntipsychotic drugs for schizophrenia are not well defined, but such information would be important fo

94 , VIM-, and NDM-producing P. aeruginosa were well defined by the conventional mCIM and eCIM testing m

95 g and correcting these offsets is key to the well-defined calendar placement of a Middle Bronze Age t

96 ntrolled with spatio-temporal precision into well-defined capillary-like fluidic microstructures with

97 pproach was exploited to create objects with well-defined catalytically active areas.

98 ell locomotion, cells break symmetry to form well-defined cell fronts and rears.

99 on by water when tuning the selectivity of a well-defined CeO(2)/Cu(2)O/Cu(111) catalyst from carbon

100 Given well-defined changes in DNA methylation that occur durin

101 the operating mode of the acoustic device is well defined, characterized and its temperature carefull

102 ic analysis of their products when acting on well-defined chitosan polymers as substrates.

103 we report the synthesis of stereochemically well-defined cis-anti-cis triquinanes (1, 2), tetraquina

104 the Poaceae TPS-a subfamily consists of five well-defined clades I-V, the common ancestor of which pr

105 average age of diagnosis is 3.4 years with a well-defined clinical presentation, older patients with

106 dependent transformation from Au(22) to both well-defined clusters and small Au(I)SR species was iden

107 advances in cluster chemistry have involved well-defined clusters containing tens or hundreds of ato

108 Mesenchymal cells formed separate, well-defined clusters specific to each gland.

109 performance has not yet been validated in a well-defined cohort of patients with PG.

110 survival in patients with glioblastoma in a well-defined cohort.

111 of receptor dimers configuration that formed well-defined complexes with CheA and CheW and promoted a

112 Moving beyond single molecules and well-defined complexes, aggregates (i.e., irregular clus

113 ial study of Pd-Cu thin-film electrodes with well-defined composition and structures, prepared by mag

114 availability of diamond samples grown under well-defined conditions has also enabled huge advances i

115 ion via reduction of the sample volume under well-defined conditions.

116 ments carried out in vitro, the loops assume well-defined configurations in situ that closely match t

117 ug sales cannot serve as voting members, and well-defined conflict of interest polices are in place.

118 active-state ternary complexes resides in a well-defined conformation, showing little conformational

119 rinated molecules possessing interesting and well-defined conformational properties.

120 ssing dispersed single-atom structures and a well-defined coordination environment, exhibit remarkabl

121 ed development to progress in the absence of well-defined correlates of immunity.

122 ize into a diverse set of superlattices with well-defined crystal symmetries and compositions.

123 n space, without the strict constraints of a well-defined crystalline symmetry and large energy barri

124 Although methods for preparing well-defined cyclic polymers have only been available si

125 Given the distinct lack of well-defined damage zones, most of the permeability incr

126 crylate monomers, including the synthesis of well-defined di- and triblock copolymers.

127 utral polymer to keep particles separated by well defined distances, allowing us to tune the attracti

128 Origin establishment requires well-defined DNA sequence motifs in Saccharomyces cerevi

129 Well-defined dynamic covalent chemistry with amines and

130 The well-defined end-members with the help of a reevaluated

131 -energy photon, electrons are emitted with a well-defined energy and a highly symmetric angular distr

132 ymph nodes and mucosal lymphoid tissues with well-defined entry and exit routes, the movement of leuk

133 This single-molecule study in a well-defined environment provides insights into the Rama

134 onducted within confining systems that offer well-defined environments, varying from droplets in micr

135 the first identified SGR form that now has a well-defined enzymatic machinery.

136 rm hydrazine (N(2) H(4) ) has been proposed, well-defined examples are without precedent.

137 lar electrocatalysts and metalloenzymes, but well-defined examples of paramagnetic nickel hydride com

138 lthough these differences are phenotypically well defined, factors contributing to the strains' abili

139 rgic population of ARC neurons distinct from well-defined feeding regulatory AgRP or POMC neurons.

140 he ability to control oxidation but retain a well-defined fibrous morphology that does not have a kno

141 ching its low-temperature FE order through a well-defined first-order phase transition.

142 In order to formulate a well-defined, focused clinical question, a framework cal

143 Although the active site subsites are well defined for a few model LPMOs, the molecular determ

144 work, we propose that most phonons are still well defined for thermal transport, whereas they carry h

145 arked discontinuous drop or latent heat at a well-defined freezing temperature, T (gm) The entropy dr

146 luding that truncation or point mutations in well-defined functional domains sensitize cancers to POR

147 are a highly desirable approach to generate well-defined functional macromolecules.

148 istinct states at rest, toward a sequence of well-defined functional states during movie viewing whos

149 y stages of nodulation are governed by a few well-defined functions, which together constitute the co

150 d polypeptides into structured proteins with well-defined functions.

151 and low temperatures, indicating that even a well-defined genetic or pharmacological manipulation may

152 aggressive forms of breast cancers that lack well-defined genetic targets.

153 leep apnea or inflammation, and increasingly well-defined genetic variants.

154 ical tools in mechanistic studies applied to well-defined genetically engineered cell lines and tumor

155 tained results pave the way to the design of well-defined glycoconjugate vaccines based on short synt

156 For many applications of well-defined gold nanoclusters, it is desirable to under

157 rly documented clinical staging, and lack of well-defined gold standards.

158 ve technical difficulty of the generation of well-defined gradients of temperature that are sufficien

159 Herein, we present the fabrication of a well-defined graphene-like t-COF on Au(111).

160 and PC2) and cultivation systems (PC3) into well-defined groups.

161 For laboratory studies, well-defined H. pylori strain B128 and its cancerogenic

162 e E6AP-binding domain in hRpn10 locks into a well-defined helical structure to form an intermolecular

163 Well-defined helical structures that have been identifie

164 ges of our society are addressed using these well-defined heterogeneous catalysts in the fields of sy

165 e report a one-pot wet-chemical synthesis of well-defined heterophase fcc-2H-fcc gold nanorods (fcc:

166 However, it is not well defined how the interplay between ER stress and inf

167 states, while the helix was found to have a well-defined hydration shell involved in the stabilizati

168 The essential role of a well-defined hydrogen-bond network in achieving chemical

169 ide flakes, pristine graphene flakes possess well-defined hydrophobic and hydrophilic regions: the ba

170 scribed; dioxygen transport follows a single well-defined hydrophobic tunnel, formed from both enzyme

171 3):167-170), for many social exposures, such well-defined hypothetical exposures do not exist or ther

172 omes framework characteristically requires a well-defined hypothetical intervention.

173 antitative potential-outcomes framework with well-defined hypothetical interventions is the wrong too

174 re embedded within 3D collagen matrices with well-defined IFs.

175 these gene expression changes have not been well defined in human hearts.

176 g17 functions in non-selective autophagy are well-defined in the literature, less attention is concen

177 antibody complex (IL-2C) administration are well-defined in the spleen and peripheral lymph nodes, h

178 formation by three orders of magnitude in a well-defined in vitro system.

179 ered effective for treating plague; however, well-defined information on the relative efficacy of var

180 studies led to identification of a broad and well-defined interaction network of these derivatives in

181 adhesion measurements in ambient air through well-defined interactions of tip-attached 2D crystal nan

182 ly controlled high-throughput preparation of well-defined interfaces containing polyatomic species ra

183 ummary measures of risk do not correspond to well-defined interventions when the individual studies a

184 Developing well-defined iron-based catalysts for olefin metathesis

185 We focus on systems involving well-defined, isolable, enantioenriched nucleophiles in

186 ting complex II (LHCII) into compositionally well-defined large unilamellar lipid bilayer vesicles to

187 metal-organic framework (2D-Co-MOF) based on well-defined layered double cores that are strongly conn

188 ormation of a completely amorphous region of well-defined length along a single silicon nanowire.

189 ear polymer, and delaminates and tears along well-defined lines in the manner of a macroscopic textil

190 teoclasts through osteocyte-derived RANKL is well defined, little is known about the regulation of os

191 replication cycle is envisioned as a single, well-defined loop with four major steps: attachment and

192 ich site-specific attachment to a chemically well-defined macroscopic surface alters the ability of s

193 ve parameters that are challenging to fit in well-defined manner, have difficulties incorporating bin

194 DNA is a versatile biomaterial with well-defined mechanical and biochemical properties.

195 anslatable acute intervention for TBI with a well-defined mechanism of action and beneficial anatomic

196 ally due to the lack of chemical probes with well-defined mechanisms of action.

197 ing blocks with large porosity and permanent well-defined micropore structures, which can overcome th

198 eduction in materials cost while providing a well-defined model system for mechanistic study.

199 ty and flexibility and exist in anatomically well-defined modules within the network.

200 With well-defined molecular architectures, viral nanocarriers

201 on studies focused on polymer samples with a well-defined molecular axis.

202 The TnT1-tropomyosin linkage yields well-defined molecular crevices.

203 hols to selectively synthesize nitriles by a well-defined molecular homogeneous cobalt catalyst is pr

204 anocavity geometry used as one terminal of a well-defined molecular junction, deposited as a self-ass

205 miRNAs have a well-defined molecular structure and this has facilitate

206 A new family of structurally well-defined molybdenum alkylidyne catalysts for alkyne

207 tameric structure that is both modular, with well-defined morphological regions, and functionally dif

208 s where native lipid membranes assemble into well-defined multilayer structures, whereas diseased lip

209 ore-shell and heterostructured nanocrystals, well-defined multimetallic random alloy and intermetalli

210 ) could be exploited toward the synthesis of well-defined nanomaterials.

211 ature, all polymers are semicrystalline with well-defined nanoscale ionic layers separated by 35-38 a

212 reactivity is efficiently controlled within well-defined nanospaces.

213 cting the assembly of biomacromolecules into well-defined nanostructures, leveraging pathway complexi

214 ve potential, and transcriptional network of well-defined neutrophil subsets, providing for the first

215 rom the niche, as well as the emergence of a well-defined number of functional stem cells, dependent

216 Surgery was indicated for well-defined objective criteria.

217 nt, connecting complementary brushes to form well-defined, one-dimensional nanostructures.

218 Well-defined optically pure transition metal (TM) comple

219 hosphorylated on only two sites in a strict, well-defined order.

220 ctivation and downstream signaling have been well defined over the last several decades.

221 Well-defined pathogenic mechanisms, and the basis for ph

222 imicry of these does not have to follow such well-defined patterns.

223 Here, we developed a class of structurally well-defined peptoids to protect DNA origamis in ionic a

224 synthetic strategies for nanostructures with well-defined physical dimensions and broad-range chemica

225 Photoprotection refers to a set of well defined plant processes that help to prevent the de

226 dimensional polymers to create topologically well-defined polygonal lattices and built-in discrete mi

227 These well-defined polymers are mucoadhesive as documented in

228 Well-defined polymers were synthesized in water under bl

229 re naive B cell repertoire consists of three well-defined populations: B1, B2 (follicular B, FOB), an

230 and octamers inserted into lipid bilayers as well-defined pores.

231 alysts less sterically demanding and lacks a well-defined preferred conformation.

232 the aftermath of closure, the importance of well-defined processes, a clear understanding of GME fun

233 Protein prenylation, a well-defined protein consensus motifs direct modificatio

234 Ca(2+), to generate the protein states with well-defined protein-metal ion stoichiometry.

235 Despite their synthetic accessibility, well-defined protocols for obtaining pure Yariv reagents

236 tion and electrooxidation of CO molecules at well-defined Pt(hkl) single-crystal electrode surfaces i

237 critical temperature, the impurities formed well-defined quasiparticles.

238 ognition by anti-CPS IgGs was examined using well-defined rabbit pneumococcal antisera.

239 Fluvoxamine gave a well-defined reduction peak at ~ - 670 mV using EPPGE.

240 Using mutagenesis reporters spanning a well-defined replicon, we show that both exonuclease-def

241 tifying resistant mutations even outside the well-defined rifampicin resistance determining region (R

242 an exemplar of major operative trauma, with well-defined risks of respiratory, cardiac, anastomotic,

243 tion of trans-ancestral pathways reflect the well-defined role for interferons in SLE and revealed pa

244 Biomarkers have a well-defined role in the diagnosis and management of chr

245 chanoafferents to five follower neurons with well defined roles in producing different feeding behavi

246 The well-defined Ru(II)-NHC-diamine complexes show unique st

247 ody, inducing motional restriction without a well-defined secondary or tertiary hydrogen bond stabili

248 this method, entirely flexible, transparent, well-defined self-activated graphene sensor arrays, capa

249 ensional (2D) in-membrane state proceeds via well-defined sequence of intermediates, including filame

250 hesis of metallo-supramolecular systems with well-defined shapes and sizes in the range of 10-100 nm

251 Oxide supports with well-defined shapes enable investigations on the effects

252 nce of applying SOMC to MOF chemistry to get well-defined single site catalyst on MOF inorganic secon

253 Overall the NMR data provide evidence for a well-defined, single-site structure of the isolated Pt s

254 t that transition metal catalysts containing well-defined sites may be intrinsically more active and

255 ve similar performance with catalysts having well-defined sites, we report the incorporation of Brons

256 arrangement of sub-wavelength patterns with well-defined sizes and geometries, in thin films.

257 Well-defined solid sources of NH(4)Pu(V)O(2)CO(3)(s) wer

258 The head has a well-defined spade-shaped prostomium with elongated vent

259 re unclear and do not allow prey to identify well-defined spatial refuges.

260 PM) that is robust to edge noise, and yields well-defined spatiotemporal communities that span forwar

261 -marked varieties' of a single species into 'well-defined species'-especially in the absence of geogr

262 The approach is used to synthesize well-defined spheroids with controlled composition and m

263 s and excitons of suitable energies and with well-defined spin structures.

264 opulations of a small number of structurally well-defined states.

265 The as-prepared deposits are able to produce well-defined steady-state voltammograms for the oxygen e

266 the cyclopropanecarboxylate ligands to have well-defined sterically demanding catalysts capable of h

267 This study utilized a well-defined stool collection from a GII.2 Snow Mountain

268 the formation of collagen-like filaments of well-defined striped morphologies.

269 he mustard family), diversified into several well-defined subclades in the virtual absence of chromos

270 who had received 1 year of treatment with a well-defined subcutaneous AIT form (Alutard SQ 510) were

271 alidate ANGPT2 as a therapeutic target for a well-defined subset of patients with melanoma.

272 wide applications of ROMP-borane polymers as well-defined supported organocatalysts.

273 of their autofluorescence and the absence of well-defined surface markers.

274 idin-4-yloxy)decyl-phosphonic acid, leads to well-defined surfaces but, following oxidation to Ru(III

275 However, the realization of a well-defined system that allows for tuning morphology an

276 enterohemorrhagic Escherichia coli contain a well-defined T3SS but in addition a second T3SS termed E

277 Adverse events with well-defined target-event associations were better predi

278 as its mainstay of treatment due to lack of well-defined targets, and recent genomic sequencing stud

279 ns (IDPs), which in isolation do not adopt a well-defined tertiary structure but instead populate a s

280 Using ciprofloxacin and ampicillin as well defined test cases, our work demonstrates that drug

281 (HLA) class I alleles and HIV progression is well defined, the interaction of HLA-mediated protection

282 atory mechanisms of these systems are mostly well defined, the toxins' biological activity and expres

283 ydroxyethyl methacrylate) (pHEMA) brushes of well-defined thickness with convenience and exceptionall

284 is work, we show that human BEX3 (hBEX3) has well-defined three-dimensional structure in the presence

285 e fuel cells, catalytic reactions occur at a well-defined three-phase interface, wherein conventional

286 of Small Tetraheme Cytochromes (STC) forming well-defined, three-dimensional networks of closely spac

287 nvariant gammadelta T cells are generated at well-defined times during development and acquire effect

288 from approaches that require user seeding or well-defined training data sets.

289 l and physiochemical features extracted from well-defined training data.

290 s on the application of stereoelectronically well-defined transition-metal fragments to stabilize sil

291 ity to produce structurally and functionally well-defined transmembrane pores opens the door to the c

292 However, the de novo design of stable, well-defined transmembrane protein pores that are capabl

293 of studying simple electrode reactions under well-defined transport conditions.

294 ls of planar nanomagnets that are coupled by well-defined, tuneable and competing magnetic interactio

295 Chronic bee paralysis is a well-defined viral disease of honey bees with a global d

296 Both species have a well-defined visual streak with a peak neuron density of

297 r coordination complexes are often extremely well-defined, with errors in the positions on the order

298 mation of planar armchair GNRs terminated by well-defined zigzag ends is confirmed by scanning tunnel

299 a family of transcription regulators with a well-defined zinc finger DNA-binding domain and there is

300 This is the first example of a well-defined Zintl-cluster-based homogeneous catalyst.