ライフサイエンスコーパス: wide-field

1 compact cell monitoring platform utilizing a wide-field (24 mm(2)) lensless holographic microscope th

2 n-correction and vitreous windowing provides wide-field 3-dimensional information of vitreoretinal in

3 LS-RESOLFT nanoscopy offers wide-field 3D imaging of living biological specimens wit

4 Most of these amacrine cells are wide field, although some are medium field.

5 We also labeled several wide-field amacrine cell types that have been previously

6 nation leads to the recruitment of GABAergic wide-field amacrine cells (WACs) endowing the DS circuit

7 Furthermore, our results reveal a class of wide-field amacrine cells (WACs) with straight, unbranch

8 of a few gamma-aminobutyric acid (GABA)ergic wide-field amacrine cells have recently been studied; ho

9 Wide-field amacrine cells span large segments of the ret

10 It is coupled to a population of wide-field amacrine cells upon which the dendrites of th

11 The presynaptic wide-field amacrine cells were reconstructed, and two ty

12 e focus of this study was on the presynaptic wide-field amacrine cells, which provided 17% of the inp

13 GABA input is provided by a subpopulation of wide-field amacrine cells, which stimulate the GABAC rec

14 acrine cells and their neurotransmitter with wide-field amacrine cells.

15 enesis with BCs, and eliminate synapses with wide-field amacrine cells.

16 ergic input originating from a population of wide-field amacrine cells.

17 es UV-sensing R7 photoreceptors and specific wide-field amacrine neurons called Dm8.

18 al window implantation procedure for chronic wide-field and cellular imaging in awake, head-fixed mic

19 In this work, we have used wide-field and confocal fluorescence microscopy to inves

20 rboxyethyl)-5-(and-6)-carboxyfluorescein] in wide-field and confocal microscopy.

21 several fluorescence imaging modes, such as wide-field and confocal one-photon and two-photon micros

22 retinal diseases, OCTA capable of providing wide-field and high definition images of retinal vascula

23 smatched polarizing optical design achieving wide-field and high-resolution holographic imaging of bi

24 ich creates detection challenges for low-NA, wide-field and high-throughput imaging systems.

25 apted this technique to different commercial wide-field and spinning-disk confocal microscopes, obtai

26 sured neural activity of retinal axons using wide-field and two-photon calcium imaging in awake mouse

27 raphic findings were associated with FEVR on wide-field angiography.

28 ometries, either confocal point-detection or wide-field area detection, typically in a total internal

29 hours with an instrument like the Murchison Wide-field Array or the Low Frequency Array but designed

30 tive adversarial-network model can transform wide-field autofluorescence images of unlabelled tissue

31 VIP+ cells revealed three predominant types: wide-field bistratified and narrow-field monostratified

32 er creation of the focus using bihemispheric wide-field calcium imaging and multielectrode arrays.

33 We used in vivo wide-field calcium imaging of the indicator GCaMP6 in he

34 ortex-wide activity of the mouse brain using wide-field calcium imaging while the mouse learned a mot

35 ation of the dorsal raphe nucleus (DRN) with wide-field calcium imaging, extracellular recordings, an

36 Using in vivo wide-field calcium imaging, we observed that SCFAs induc

37 d a brain machine interface (BMI) task using wide-field calcium signals.

38 r, it suppresses inhibition imposed on these wide-field cells by another subpopulation of upstream GA

39 VIP-1 amacrine cells are bistratified, wide-field cells that ramify in strata 1, 4, and 5, VIP-

40 Wide-field, cellular-resolution GCamP7b calcium imaging

41 Availability of real-time, wide-field chemical information should enable more compl

42 A line-focused laser and wide-field collection optics are used to excite and coll

43 icroperimetry, optical coherence tomography, wide-field color fundus photography, and fluorescein ang

44 nt deposits were characterized clinically by wide-field color photography, fundus autofluorescence im

45 ng axons used two center components-an early wide-field component and a delayed narrow-field componen

46 This UV-based wide-field computational imaging platform could be valua

47 e properties allow for use of DiB-splits for wide-field, confocal, and super-resolution fluorescence

48 d sub-synaptic protein analysis method using wide-field data from deconvolution array tomography (ATD

49 We show evidence for a mechanism involving wide-field dendritic inhibition that exceeds the retinot

50 We outline the basic principles of wide-field detected FT-CARS microscopy and demonstrate h

51 sform coherent anti-Stokes Raman scattering (wide-field detected FT-CARS) microscopy capable of acqui

52 croscope capable of broad spectral coverage, wide-field detection, and diffraction-limited spectral i

53 igital imaging by nonphysician staff using a wide-field digital camera.

54 d digital imaging by trained imagers using a wide-field digital camera.

55 nerve abnormalities were documented using a wide-field digital imaging system.

56 In this multicenter study, 260 wide-field digital photographs of 52 patients were prese

57 f the Mueller polarimetric endoscope include wide field early epithelial cancer diagnosis, surgical m

58 Using wide-field epifluorescence and two-photon imaging we dem

59 cently labeled single-stranded DNA probes, a wide-field epifluorescence microscope and a spot-detecti

60 antibody-UCNP conjugate were counted under a wide-field epifluorescence microscope equipped with a 98

61 ed DNA oligonucleotides) in combination with wide-field epifluorescence, confocal or instant structur

62 our technique using the challenging case of wide-field, epifluorescence microscope image stacks from

63 ic antigen (PSA) are detected and counted by wide-field epiluminescence microscopy (digital readout).

64 Of note, RNA imaging was feasible under wide-field excitation conditions.

65 wide-field SLO images, and examination plus wide-field FA.

66 We report scan-less wide-field FLIM based on a 0.5 MP resolution, time-gated

67 Ultra-wide-field fluorescein angiography (UWFA), which capture

68 ic findings that are easily identified using wide-field fluorescein angiography.

69 ch other, enabling 3D refocusing of a single wide-field fluorescence image to match confocal microsco

70 Wide-field fluorescence images are often corrupted by ha

71 g from the flow dynamics was confirmed using wide-field fluorescence imaging of rhodamine 6G (R6G).

72 e analysis by implementing high-sensitivity, wide-field fluorescence imaging on a confocal Raman micr

73 In this study, we used high-resolution, wide-field fluorescence imaging to investigate the regul

74 ement of concentration dynamics using simple wide-field fluorescence imaging.

75 itation of the NPs with polarized light on a wide-field fluorescence microscope enabled monitoring of

76 e require are straightforward and use only a wide-field fluorescence microscope.

77 whole brain axial and coronal images using a wide-field fluorescence microscope.

78 fluorophores were simultaneously tracked by wide-field fluorescence microscopy and their sizes were

79 ponses obtained in live cells using standard wide-field fluorescence microscopy imaging.

80 er-light intensities typical of conventional wide-field fluorescence microscopy, an oxygen-dependent

81 As an extension of wide-field fluorescence microscopy, it is inherently cap

82 mersion objectives could outperform standard wide-field fluorescence microscopy, with, for example, a

83 urthermore, FlicR1 can be easily imaged with wide-field fluorescence microscopy.

84 Wide-field fluorescence polarization images were excited

85 t cancer margins using combined dye-enhanced wide-field fluorescence polarization imaging for en face

86 The wide-field fluorescence videos acquired reveal that a si

87 vity of large ensembles in subregion CA1 via wide-field fluorescent microscopy during a novel behavio

88 sing interest owing to their applications in wide fields from bioengineering to electrochemical devic

89 re recruited in 2007 and 2016 to classify 34 wide-field fundus images of ROP as plus, pre-plus, or no

90 ses drive inhibition of rod BCs via motif C1 wide-field GABAergic ACs (gammaACs) and motif C2 narrow

91 nhibition via motifs C4 and C5 driven by OFF wide-field gammaACs and narrow-field GACs, respectively.

92 sistent with the idea that the proportion of wide-field ganglion cell types increases in peripheral r

93 Similar to wide-field ganglion cells, the spatial extent of the exc

94 Using wide-field GCaMP imaging, the development of neural resp

95 We developed a miniature wide-field, gradient-index (GRIN) optical probe designed

96 brain at multi-scale, the neural network in wide-field has been visualized in detail by taking advan

97 Here we demonstrate a low cost wide field high definition Mueller polarimetric endoscop

98 tensity images in Fourier space to produce a wide-field, high-resolution complex sample image.

99 t of odor modulation, nor is the neighboring wide-field "HSE" neuron.

100 We present a wide-field hyperspectral approach to spatially delineate

101 CS microscope combines a dynamic structured wide-field illumination and a fast and sensitive single-

102 molecules at submillisecond resolution using wide-field illumination and camera-based detection metho

103 nal allows for fast and direct hyperspectral wide-field image acquisition, while minimizing sample da

104 ion is performed numerically on the acquired wide-field image data, and thus relies on a software imp

105 We demonstrate the use of Pockels cells for wide-field image gating with nanosecond temporal resolut

106 this framework, we improve the resolution of wide-field images acquired with low-numerical-aperture o

107 hysically narrowing the field of view of the wide-field images), examination plus ultra wide-field SL

108 entional imaging, and in 27 of 43 (63%) with wide-field imaging (P = .27).

109 s work, we present a new technique, solution wide-field imaging (SWiFi) of diffusing molecules, as an

110 Combining wide-field imaging and a mosaic algorithm developed in-h

111 management change with the use of the ultra wide-field imaging and angiography (P < .001).

112 We present a wide-field imaging implementation of Fourier transform c

113 Lens-free holographic microscopy can achieve wide-field imaging in a cost-effective and field-portabl

114 functional connectivity was evaluated using wide-field imaging in lightly anesthetized Emx1-creXRosa

115 In particular, because of vignetting, wide-field imaging increases occurrence of low-OCT-signa

116 xample in studies of cell collectives, where wide-field imaging is desired.

117 temporal resolution enables new methods for wide-field imaging like time-of-flight, gated detection,

118 design limitations, has suggested that ultra wide-field imaging may alter management decisions compar

119 down to 20 mV with multiple NV centers in a wide-field imaging mode.

120 This method can be useful for wide-field imaging needs in telepathology applications a

121 and provides the conditions for quantitative wide-field imaging of fluorophore dynamics at or near th

122 such spectral demultiplexing approaches for wide-field imaging of multicolor fluorescent objects on

123 , we here describe a system for simultaneous wide-field imaging of neuronal calcium activity from at

124 We demonstrate wide-field imaging of the propagation of electrical stim

125 Wide-field imaging provides a tool for comprehensive cir

126 Both confocal and wide-field imaging registered a consistent decrease in s

127 Wide-field imaging revealed widespread ramps of Ca(2+) a

128 Here, we use defocused wide-field imaging to examine the unidirectional rotatio

129 We anticipate GCAMP wide-field imaging will enable longitudinal studies duri

130 resolution, higher surface sensitivity, and wide-field imaging with dense spatial sampling.

131 agement changed based on the availability of wide-field imaging, compared with standard examination a

132 tral domain optical coherence tomography and wide-field imaging, have resulted in the detection of su

133 aphic analysis of the diffraction pattern in wide-field imaging.

134 ning microscopes, line imaging and global or wide-field imaging.

135 esirable in high-speed, high-resolution, and wide-field imaging.

136 croscopy with point mapping is compared with wide-field immunofluorescence images.

137 llar Golgi cells (GoCs), a type of mammalian wide-field inhibitory interneuron observed in the granul

138 Wide-field inhibitory interneurons globally inhibit neig

139 Here, we identify a wide-field inhibitory neuron that responds to visual sti

140 position based on an optical microscope with wide-field interferometric detection of absorption-induc

141 On the other hand, wide-field interferometric microscopy can be used to det

142 Using an advanced synchrotron-based wide-field IR imaging system and state-of-the-art Mie sc

143 of neurons using two-photon (jGCaMP7s,f) or wide-field (jGCaMP7c) imaging.

144 creases the domain wall velocity measured by wide-field Kerr microscopy by 30-100%, with larger chang

145 t promise for studying chemical dynamics and wide-field label-free biomedical imaging.

146 opy can increase the spatial resolution of a wide-field light microscope by a factor of two, with gre

147 Visual experiments using wide-field looming stimuli revealed retinotopic maps tha

148 environmentally controlled experiments with wide-field low photo-toxic imaging, which we demonstrate

149 ensors, opening a new temporal dimension for wide-field low-light microscopy.

150 An ultrafast wide-field macroscope was developed to optically map act

151 Scanning single-spin and wide-field magnetometry reveal a parabolic Poiseuille pr

152 esponsive imaging agents, which we apply for wide-field mapping of targets in rat brains using functi

153 mediated by presynaptic disinhibition from a wide-field mechanism extending >0.5 mm along the retinal

154 API phase that was missed by the spontaneous wide-field method and bulk Raman spectroscopy.

155 interactions was possible in a conventional wide field microscope, yielding detection limits of appr

156 Exploiting an automated, mutli-color wide-field microscope and data analysis package, we anal

157 cept to fluorescence detection with standard wide-field microscope optics.

158 in less than 15 min using an epifluorescent wide-field microscope with a computer controlled transla

159 These experiments, using a wide-field microscope, a previously generated reporter m

160 When a single molecule is detected in a wide-field microscope, the image approximates the point

161 These methods generally use wide-field microscopes and two-dimensional camera detect

162 lementations, allowing easy integration with wide-field microscopes.

163 Wide-field microscopy allows parallel optical and magnet

164 able solution for cost-effective and compact wide-field microscopy and sensing needs on a chip.

165 ate less cytotoxicity than those of standard wide-field microscopy at constant absorbed light-dose.

166 Colocalization of two-color labels using wide-field microscopy is a method to infer these interac

167 main, although they appear colocalized using wide-field microscopy.

168 in precipitation by a systematic and nation-wide field monitoring campaign.

169 Wide-field mosaics indicated persistent disrupted orient

170 vers and by use of a fully automated method; wide-field mosaics of subbasal nerve architecture by use

171 s for a broad range of applications in which wide field motion detection is at a premium, such as col

172 ect recording from downstream neurons in the wide-field motion pathway reveal that local elementary m

173 g these activities, with neurons that encode wide-field motion previously identified in insects, such

174 optomotor reflex that compensates for visual wide-field motion was reduced in food-deprived flies.

175 We characterize a wide-field motion-selective interneuron of the lobula pl

176 thought to be subtracted on the dendrites of wide-field motion-sensitive lobula plate tangential cell

177 ions about different axes to study how H1, a wide-field motion-sensitive neuron, encodes preferred ya

178 y insects, including flies, moths, and bees, wide-field motion-sensitive neurons in the third optic g

179 ing only visual cues, we recorded from their wide-field motion-sensitive neurons.

180 feed into large tangential cells that signal wide-field motion.

181 ong, nondirectional responses to high-speed, wide-field motion.

182 tion (Hb(sat)) acquired concurrently using a wide-field multicontrast optical imaging system.

183 Furthermore, its wide-field nature makes it light-efficient and decouples

184 vealed that the gain and frequency tuning of wide-field neurons change during flight, and that these

185 Genetically silencing wide-field neurons increased behavioral responses to slo

186 lamp electrophysiology, we found that lamina wide-field neurons respond to low-frequency luminance fl

187 Such signals are provided by wide-field neurons sampling motion directions at multipl

188 We describe a class of wide-field neurons that provide feedback to the most per

189 ons convey direction-selective inhibition to wide-field neurons with opposite preferred direction and

190 Furthermore, using wide-field non-perfusion analysis in diabetic retinopath

191 objective-type TIRF microscopes that allows wide-field observations of fast-diffusing molecules down

192 To obtain ultra-wide-field OCT and OCTA images in neonates with ROP usin

193 Acquisition of wide-field OCT and OCTA images using a handheld prototyp

194 es using a handheld prototype OCTA and ultra-wide-field OCT device.

195 Wide-field OCT images demonstrated schisis cavities only

196 This study reports on OCTA and ultra-wide-field OCT images in 4 neonates with various stages

197 ially available devices able to obtain ultra-wide-field OCT or OCTA images in neonates.

198 Wide-field OCT scans over the discs were used to measure

199 Wide-field OCTA technology will be an important next ste

200 inography, optical coherence tomography, and wide-field ocular fundus photography was performed on -1

201 ectric field, which is applicable across the wide field of perovskite materials science.

202 ial resolution, spectroscopic imaging over a wide field of view (> 6 cm(2)), with simplified animal h

203 real-space images with nanoscale resolution, wide field of view and compressed sensing speed-up.

204 tection of dysplasia, provided they permit a wide field of view and highlight abnormalities in real t

205 ages over their planar counterparts, such as wide field of view and low aberrations.

206 nables tracking with nanometer accuracy in a wide field of view and tracking of many particles.

207 ows for an increased power collection over a wide field of view by increasing the effective optical i

208 t light on the hologram, a high contrast and wide field of view CAMBRIDGE image is produced.

209 e matter structure achieved in vivo across a wide field of view of several millimeters.

210 ed the combination of spatial resolution and wide field of view sufficient to map distributed brain f

211 an samples with unprecedented resolution and wide field of view using only endogenous contrast.

212 The possibility to select a wide field of view with a good spatial resolution along

213 aging was the most practical considering its wide field of view, background noise filtering capabilit

214 sensing characteristics such as an extremely wide field of view, high resolution and sensitivity with

215 coordinated responses to information over a wide field of view, involving both central and periphera

216 to capture images, offering an exceptionally wide field of view.

217 l FPA provides a low-aberration image with a wide field of view.

218 prohibit detailed structural imaging across wide fields of view and hinder intraoperative tumor marg

219 microcolony-counting system implemented on a wide field-of-view (FOV), on-chip microscopy platform, t

220 We hypothesized that wide field-of-view (panoramic) mapping of both atria wou

221 This system greatly facilitates underwater wide field-of-view fluorophore surveying during both nig

222 DIH) is a promising technology for portable, wide field-of-view imaging.

223 ative changes to retinal hemodynamics over a wide field-of-view in a rodent model.

224 tocol for the implementation of the improved wide field-of-view nematode tracking platform (WF-NTP),

225 nitoring of biomolecular interactions over a wide field-of-view of >20 mm(2).

226 canner (CZCS, 1979-1986) and the Sea-viewing Wide Field-of-view Sensor (SeaWiFS, 1998-2010).

227 d wavelength range from 640 to 1290 nm and a wide field-of-view up to +/- 40 degrees .

228 To achieve high-resolution and wide field-of-view, digital holographic imaging techniqu

229 nsumer camera, was used to capture wide-band wide-field-of-view fluorescence images during a field de

230 Wide-field-of-view mesoscopic cortical imaging with gene

231 ellular glutamate sensor iGluSnFR to perform wide-field-of-view mesoscopic imaging of cortex in both

232 nd report some of their emerging results for wide-field on-chip microscopy, such as the achievement o

233 many EMDs is pooled in neurons sensitive to wide-field optic flow.

234 We used wide-field optical imaging to measure changes in odor re

235 in particular, when combined with long-term, wide-field optical imaging.

236 Here we used wide-field optical intrinsic signal imaging in mice to e

237 awake and anesthetized Thy1-GCaMP mice using wide-field optical mapping.

238 onfirmed by high-resolution atomic force and wide-field optical microscopy, including 2D and 3D phosp

239 retrieve this near-field information through wide-field optics in a spatially resolved manner, and th

240 We propose that wide-field optogenetic suppression of inhibition under p

241 totype devices that collect fluorescence for wide-field or microscopic images have been developed.

242 Noncontact ultra-wide-field oral fluorescein angiograms captured using th

243 owledge, the acquisition of noncontact ultra-wide-field oral fluorescein angiograms in premature infa

244 is also undergoing major advances including wide-field photography, autofluorescence, and high-resol

245 p biomicroscopy, dilated fundus examination, wide-field photography, fundus autofluorescence imaging,

246 We investigated wide-field photostimulation in cortical networks in vitr

247 terminals impinging on recorded neurons with wide-field photostimulation.

248 Finally, we demonstrate the potential of wide-field polarimetry for rapid inspection of opto-vall

249 e identify an ON-type orientation-selective, wide-field, polyaxonal amacrine cell (PAC) in the rabbit

250 The wide-field qFI technique has broad implications for intr

251 Wide-field quantum cascade laser (QCL) infrared imaging

252 pled to Nitrogen Vacancy (NV) centers over a wide field range (1 mT-7 T).

253 oscopy platform, providing the endoscopist a wide-field red-flag technique for adenoma detection.

254 Nonphysician trained readers evaluated wide-field retinal image sets for characteristics of ROP

255 Wide-field retinal imaging revealed the presence of peri

256 ut of 62 patients with Stargardt disease and wide-field retinal imaging, 14 had peripheral pigmented

257 with peripheral pigmented retinal lesions on wide-field retinal imaging.

258 Here, we discovered a new wide-field RGC type receiving the same cone-opponent inp

259 ated patterns of motion such as contraction, wide-field rotation or luminance change.

260 dard clinical examination, followed by ultra wide-field scanning laser ophthalmoscope (SLO) imaging a

261 in the living human eye with two-wavelength, wide-field scanning laser ophthalmoscopy (SLO), and inve

262 By developing a wide-field scheme for spectral measurement and implement

263 Wide-field SD-OCT is a useful tool for evaluating comple

264 mphrey visual field, fundus photography, and wide-field SD-OCT, a montage technique to generate SD-OC

265 hus, our data demonstrate that sustained and wide-field signals are essential for elementary motion p

266 e demonstrates unmatched low-photon-count 3D wide-field single-molecule localization performance.

267 d as the transducer in a massively parallel, wide field, single molecule detection scheme for quantit

268 e wide-field images), examination plus ultra wide-field SLO images, and examination plus wide-field F

269 th and speed of excitation on both local and wide-field spatial scales.

270 -cone-driven surround inhibition mediated by wide-field spiking GABAergic amacrine cells.

271 In comparison with wide-field spontaneous Raman chemical imaging, BCARS acq

272 ents with a high clinical suspicion for PDR, wide-field SS OCTA likely will be the only imaging metho

273 From January through May 2018, wide-field SS OCTA was performed on 20 eyes with treatme

274 baseline and imaged serially after PRP using wide-field SS OCTA.

275 Wide-field SS-OCT and SS-OCTA provide detailed visualiza

276 Wide-field stereofluorescence microscopy was performed t

277 en test the model predictions in a community-wide field study of African savannah herbivores using mu

278 The method relies on the wide-field surface plasmon microscopy (SPM).

279 after the Big Bang) that was discovered in a wide-field survey.

280 clusters and star-forming regions as well as wide-field surveys, but these studies are incomplete for

281 Wide-field swept-source (SS) OCT angiography (OCTA) was

282 We aim to describe wide-field swept-source OCT (SS-OCT) and swept-source OC

283 cting the image of a complex two-dimensional wide-field target through a highly scattering medium.

284 ed the way for phase imaging in a variety of wide-field techniques, including electron, X-ray and opt

285 tric spontaneous neural activity revealed by wide-field Thy1-GCaMP imaging may depict the neural foun

286 Automated FLIM is implemented using wide-field time-gated detection, typically requiring onl

287 Here we use wide-field time-lapse and three-dimensional structured i

288 This work describes the performance of a wide-field, time-gated microscope with respect to its ab

289 hotonic crystal fiber for temporally focused wide-field two-photon endomicroscopy.

290 For endomicroscope application, wide-field two-photon excitation has the advantage of re

291 However, wide-field two-photon excitation requires peak power tha

292 types: an asymmetric medium-field type and a wide-field type.

293 s field of view and up to 100 degrees (ultra-wide-field) using a contact lens-based approach in a sin

294 n-labeling of recorded neurons revealed that wide-field vertical (WFV) and non-WFV cells were activat

295 A wide-field virtual reality environment simulated a daily

296 interneurons that integrate information from wide-field visual interneurons and project directly to m

297 torque in tethered flying moths experiencing wide-field visual stimuli.

298 n of two classically defined cell types, the wide-field (WF) and narrow-field (NF) vertical neurons,

299 Here, we show that wide-field (WF) cells in retino-recipient layers of the

300 These wide-field (WF) cells respond strongly to small objects