ライフサイエンスコーパス: widen

1 ions, the constriction did not significantly widen.

2 continuously recruited to the pores as they widen.

3 pair the crack as it grows and progressively widens.

4 age at first presentation with heart failure widened.

5 es better pre-organized, and its entrance is widened.

6 of posterior skull bones important for gape widening.

7 rigin works at TEM boundaries to limit their widening.

8 ved structures, and, eventually, fusion pore widening.

9 esence of retinopathy and/or retinal venular widening.

10 ascular resistance consistent with capillary widening.

11 omotes SpM-SHF lengthening and restricts its widening.

12 of HPV vaccination in England will initially widen a pre-existing disparity in the incidence of HPV-r

13 y implicated in substrate recognition, which widens a central cavity of the BBSome.

14 surrounding protein shell that dramatically widens a neck of the pore through a concertina of amino

15 Coupled with interoperability of data to widen access to all stakeholders, seamless connectivity

16 ctive site residues, the structures reveal a widened active site cavity near the nucleobase moiety co

17 blacks' mental health advantage over whites widened after adjusting for socioeconomic factors.

18 mechanics, as indicated by greater neuropore widening after ablation.

19 The groove widening aids the approach of, and the jump to, a new wa

20 anoscale particles have been incorporated to widen and diversify the scope of the light-driven liquid

21 xon bundle in the midbrain was significantly widened and appeared disorganized, showing aberrant post

22 tissue disorder that results in aortic root widening and aneurysm if unmanaged.

23 linked collagens, and fibrotic septae showed widening and collagen fibrils splitting, reminiscent of

24 ounts for f(T)- and hearing loss-related ERB widening and ERB overlaps and gaps of CR tone alignments

25 ten the vertical cell cross-section, thereby widening and flattening the nucleus, and the resistance

26 century health-poverty trap and the further widening and hardening of socioeconomic inequalities in

27 s (MMPs) inhibitor, to attenuate aortic root widening and improve aortic contractility and elasticity

28 sulted in significant anterior chamber angle widening and increased anterior chamber area.

29 een tobacco promotion and tobacco control is widening and tobacco control may be losing ground to tob

30 for testing the cause of tip-to-base conduit widening and underscore the need to study plant hydrauli

31 way of tailoring the blazing operation, for widening and/or controlling of blazing bandwidth and inc

32 We show that T-Plastin widens and lengthens protrusions and is specifically enr

33 uring cell expansion, the plasmodesmata pore widens and the two membranes separate, leaving a cytosol

34 ridges, such that these structures lengthen, widen, and change position in response to traffic levels

35 en the United States and Canada is large and widening, and it apparently reflects the inefficiencies

36 ession analyses, greater postoperative angle widening as defined by change in AOD750 was associated w

37 The impact of twisted light is widening as recent numerical calculations provided solut

38 .1 mm) were significant predictors of AOD500 widening at 6 months.

39 0% from baseline along with inadequate angle widening at the month 1 or month 3 visit.

40 however, the difference between these groups widened between 2004 (adjusted risk ratio, 1.72 [95% CI,

41 even more important as our analytical focus widens beyond coding exons.

42 tamate tail of THF remains weakly bound in a widened binding cleft.

43 DeltaE2)) in 129 sv mice results in QRS, QTc widening, bundle block and STc narrowing at 2-4 months o

44 n ever- and never-institutionalized children widened by adolescence; and (iii) early difficulties in

45 They are widened by clustering of involatile solution impurities,

46 as the ligand entrance and the gap cannot be widened by internal dynamics.

47 The greatest widening by ASOCT was observed in eyes with features mos

48 capping protein participates in stereocilia widening by preventing newly elongating actin filaments

49 Further, increased Cdc42 activation by Gef1 widens cell diameter and alters tip curvature, counterin

50 s were used to determine predictors of angle widening (change in mean angle opening distance [AOD750]

51 In the widened channel in the open conformation, these same res

52 This study aimed to evaluate whether septal widening could represent an "alert" signal for AMR.

53 leaflets of each membrane and promote stalk widening, curvature, and eventual fusion.

54 In addition, the BIF is enhanced by the widened depletion region in the device.

55 capillary resistance from capillary diameter widening detected in earlier histological studies.

56 Social determinants have created widening disparities in end-of-life care.

57 concluded that the pores were not static but widened dramatically to release molecules of different s

58 g, in both regions firing rate distributions widened during REM due to differential changes in high-

59 Widening economic inequality in the USA has been accompa

60 h aqueous or non-aqueous electrolyte enables widened electrochemical potential window thus may provid

61 Hoepner LA, Whyatt RM, Widen EM, Hassoun A, Oberfield SE, Mueller NT, Diaz D, C

62 ics has introduced precision medicine into a widened field of complement-mediated diseases.

63 the point of rupture, promoting fusion pore widening for RNP release.

64 degree below which the attenuation bandwidth widens; for high disorder levels, the band gap mistuning

65 This window widens from seconds, in the case of single cation/halide

66 and highest life expectancies and HALE have widened, from 2.5 to 3.1 years and from 2.3 to 2.7 years

67 rotein functions are essential to bridge the widening function annotation gap especially since <1.0%

68 The widening function annotation gap in protein databases an

69 ental care needs may be falling into an ever widening gap between assistant and registered nurses.

70 This deceleration resulted in a widening gap between England and Wales and the comparato

71 African-American women could correspond to a widening gap in actual health outcomes.

72 Infants in all three clinical groups had a widening gap in scores from the no-exposure group at day

73 This diversity, in turn, contributes to a widening gap or differences in levels of maternal mortal

74 The widening gap reported between birth weights of babies bo

75 Widening gaps in adolescent health could predict future

76 dengue fever (chi(2)=135.9, p<0.001); and a widening geographic range of acquisition of chikungunya

77 erage global incomes roughly 23% by 2100 and widening global income inequality, relative to scenarios

78 The idea that tip-to-base conduit widening has a nonadaptive cause, with temperature, drou

79 smoking cessation services, contributing to widening health inequalities and reduced life expectancy

80 e than the wider population, contributing to widening health inequalities.

81 tation, favored by natural selection because widening helps minimize the increase in hydraulic resist

82 ent error, the HRs increased and the 95% CIs widened [HR = 1.19 (95% CI: 1.02, 1.39) for BS and HR =

83 e kin and that this gap in availability will widen in the coming decades.

84 The thermoneutral zone was also widened in both male and female HET mice.

85 cytosolic constriction for Cl(-) passage is widened in CLC-K such that the kinetic barrier previousl

86 pain between the more and less educated has widened in each successive birth cohort.

87 s lived in full health, as measured by HALE, widened in several states.

88 he linear detection range could be obviously widened in the presence of self-linkable PMGO-from 0.05

89 ory to confirm the potential value of septal widening in the multidisciplinary approach of AMR.

90 uction speed that accompanies the axon shaft widening induced by high-frequency AP firing.

91 rogrammes), although beneficial overall, can widen inequality gaps.

92 expanding hemifusion diaphragm, and fissure widening initiating pore formation in a hemifusion diaph

93 e reason to suspect that tip-to-base conduit widening is an adaptation, favored by natural selection

94 thin a hydrophobic "neck" of the pore, which widen it, cause the channel to be constitutively active,

95 ring a confined space, and they dramatically widened it within dozens of milliseconds when flying tow

96 he implementation of GTD, which will further widen its clinical application.

97 EBM needs to widen its scope beyond drugs and devices to address many

98 Biocatalysis has widened its scope and relevance since new molecular tool

99 on South Africa, we examined the impact that widening LAM test eligibility would have on TB incidence

100 ealth and social policies are needed to curb widening life expectancy inequalities, help deprived dis

101 al sensor and 50 cells/mL for QCM sensor), a widened logarithmic range of detection (i.e., 3-7 for pi

102 ments have A-form C3' endo sugar puckers but widened major groove widths, giving the RNA an overall a

103 s conventionally associated with AMR, septal widening may represent an "alert" signal to look into lu

104 ing deformations in the steps of fusion are: widening of a hydrophobic fissure in bilayers for stalk

105 r adjusting for covariates, the magnitude of widening of AOD500 was not associated significantly with

106 hances neural responsivity across cortex and widening of attention to environmental stimuli regardles

107 ons in inlet channels, leading to artificial widening of DI versus cell size plots.

108 ependence of susceptibility, the substantial widening of dielectric spectrum on cooling and the resul

109 ur study species resulted predominantly in a widening of habitat associations under climate change.

110 Finally, alongside protracted conflicts, widening of health and socioeconomic inequalities betwee

111 new hypomethylated regions and by extensive widening of hypomethylated intervals in ancestral specie

112 Biopsies also showed widening of intercellular spaces (confirmed by CLE), and

113 Transmission electron microscopy revealed widening of intercellular spaces with chromatin condensa

114 e skin, and result in desmosome aggregation, widening of intercellular spaces, and lipid secretory de

115 A widening of its focus to understand better the interconn

116 n driven largely by soaring top incomes, the widening of survival inequalities has occurred lower in

117 Widening of the angle opening distance (AOD) 500 mum fro

118 and cation engineering leads to a systematic widening of the anti-solvent processing window for the f

119 egrin is required for both acute and chronic widening of the arterial lumen in response to hindlimb i

120 how that there is considerable evidence of a widening of the BMI distribution in populations over tim

121 We did not observe a widening of the breadth or an increase in the potency of

122 wever, this outcome was not accompanied by a widening of the breadth or an increase in the potency of

123 One obvious development addresses the widening of the definition of what to call a cluster: fr

124 d pressure in the right atrium may result in widening of the foramen and consequently, cause serious

125 mulations reveal that sterol egress involves widening of the fracture, penetration of water into the

126 he proximodistal shortening of the snout and widening of the hard palate is common to brachycephalic

127 on of the central BN core induces a dramatic widening of the HOMO-LUMO gap and an enhancement of the

128 inhibitory balance toward excitation and the widening of the integration time window were both smalle

129 onformation of a Kir K(+) channel to prevent widening of the narrow collar.

130 plate cells fail to constrict, resulting in widening of the neural plate midline and defective neura

131 f 194 eyes, 45.4%) ERMs were associated with widening of the outer nuclear layer and loss of the fove

132 ) ion in the selectivity filter controls the widening of the pore as shown in crystal structures and

133 the pelvis taken six months before showed a widening of the proximal right femoral physis.

134 Dark adaptation at dusk triggered extensive widening of the rhabdoms and crystalline cone tips.

135 ain radiograph in frog leg position showed a widening of the right proximal physis below the right fe

136 Moreover, widening of the second-tallest stereocilia rank (row 2)

137 ctions controlling ion permeation, including widening of the selectivity filter to enhance calcium pe

138 Later deepening and widening of the South Atlantic, together with gateway op

139 treated tumors appeared less condensed with widening of the stromal areas which increased at 48 and

140 ropics and subtropics, in conjunction with a widening of the subsiding branches of the HC, resulting

141 in ethnic minorities, we predict an initial widening of this gap, with cervical cancer incidence in

142 Laser peripheral iridotomy resulted in angle widening on ASOCT with significant increases in AOD750,

143 ostic strategy as a rational approach to the widening opportunities for the use of phenotype-targeted

144 diagnosis, which is a prerequisite for using widening options of personalized therapy.

145 s consistency in promoting root lengthening, widening or apical closure.

146 ucial to speed up biocatalyst design, and to widen our knowledge about sequence function relationship

147 gh performance computing, have significantly widened our analytical window and have enabled increasin

148 vast amount of data generated over time has widened our view of the etiology of caries and periodont

149 It widens our knowledge on the enzyme diversity world and d

150 t pain, as well as whether these differences widened over time.

151 tely 100 m incision; and approximately 160 m widening over 6 years) principally through fluvial pluck

152 stunting outcomes persisted, with the latter widening over time.

153 f minority patients, and the gap seems to be widening over time.

154 rmal distribution fit to the data is falsely widened, overestimating the mean, highlighting the impor

155 unctions (TJs), down-regulation of which may widen paracellular spaces between cells, allowing greate

156 nique biomedical science education centre, a widening participation and outreach project in London's

157 that EADs of various types are generated by widening (particularly asymmetrically) the window I(CaL)

158 rown ratio), delayed tooth root development, widened PDL space, and interradicular alveolar bone defe

159 d seedling selection (MASS) targeted towards widening peach germplasm for maturity, particularly earl

160 We combined data of widened periapical spaces (WPSs) and apical rarefactions

161 ocilia developed in specific stages, where a widening phase is sandwiched between two lengthening pha

162 2) O(3) -ZISe-Mo is mainly attributed to its widened photoresponse range and effective carrier separa

163 neral density, abnormal dentin architecture, widened predentin and irregular predentin-dentin boundar

164 iameter of xylem water-conducting conduits D widens predictably with distance from the stem tip L app

165 of solvent into a crack as it propagates and widens, providing unique insights into the activation an

166 functional class II or III heart failure and widened QRS.

167 n implantable cardioverter-defibrillator and widening QRS.

168 ing worm-derived immunotherapies for an ever-widening range of inflammatory diseases, including, for

169 There is a widening range of tests available for detecting pathogen

170 ls increased over time for males, suggesting widening rural-urban disparities (1996-1998: adjusted in

171 esults in significant anterior chamber angle widening seen on both ASOCT and gonioscopy, although som

172 ooling (warming), strengthening (weakening), widening (shrinking) since the mid-2000s (early 1990s) r

173 inputs, the window of coincidence detection widened significantly with increasing gNa, indicating th

174 Integrating this apex geometry with a widening slope, analogous to cactus spines, directly cou

175 gesting that Incredible Years is unlikely to widen socioeconomic inequalities in conduct problems.

176 The development of Dupilumab and the widening spectrum of its clinical applications is releva

177 Presynaptic mitochondrial cristae were widened, suggesting a sustained energy demand.

178 revealed mild craniodorsal cerebellar sulci widening, supportive of cerebellar atrophy.

179 tly shifting activation V(0.5) (asymmetrical widening) than inactivation V(0.5) ; for example, a 15 m

180 we find that Boc deletion results in facial widening that correlates with increased HH target gene e

181 pyramidal neurons revealed action potential widening that could account for enhanced neurotransmitte

182 l data guide rational design of mutants that widen the active site to better accommodate protein-conj

183 These data widen the allosteric and pharmacological landscape of NM

184 brane via non-endocytic pathways, which will widen the applicability to a variety of plant cells.

185 ase transformation that has the potential to widen the application window of Ti alloys, the most impo

186 er levels of Sr alloyed into the PbTe matrix widen the bandgap and create convergence of the two vale

187 Our results widen the basis for comparative studies of the vertebrat

188 eld of view, and on the other hand, it could widen the beam to increase the space that it senses.

189 tal assay time of 27min, which can hopefully widen the detection window for Zika viremia and is there

190 Elevated atmospheric CO2 may widen the disparity in protein intake within countries,

191 (WiS) electrolytes provide a new pathway to widen the electrochemical window of aqueous electrolytes

192 ther, using blood will reduce animal use and widen the experimental design options for studying the e

193 stantially expand statin recommendations and widen the gap of statin underutilization in all groups.

194 g a new source of nematode resistance and to widen the genetic basis of agronomically adapted peanut

195 ation from the second trimester onward would widen the immunization opportunity window and could impr

196 ses identified but not yet characterized may widen the landscape of possible target sequences.

197 in all the subunits of RNAP and transiently widen the main cleft of RNAP to facilitate DNA promoter

198 ntrol system whereby actin waves transiently widen the neurite shaft to allow increased microtubule p

199 The approach was to widen the pool of M. bovis antigens that could be used a

200 on which catalyst or reagent is chosen would widen the possible structures one could obtain.

201 The intention of this article is to widen the practical use of IDEAL by clarifying the ratio

202 , acyl and oligo(lactic acid) ester prodrugs widen the range of anticancer drugs that can be tested s

203 vices onto high temperature textiles, but to widen the range of applications future research is requi

204 g and vaccine delivery to the skin and could widen the range of compounds that can be topically admin

205 y biological activities, these two molecules widen the range of potential beneficial effects of wine

206 emPowERment index (SWPER), has potential to widen the research on women's empowerment and to give a

207 e inhibitor proved to be an efficient way to widen the scope of the proposed experimental approach to

208 utic potential and novel modes of action, to widen the scope of treatment and to overcome emerging dr

209 detailed in this paper, make it necessary to widen the spectrum of possible diagnoses.

210 better characterize disease progression and widen the spectrum of therapeutic options.METHODSWe perf

211 research questions for the future that could widen the success of cancer immunotherapy.

212 eted therapies, both as a monotherapy and to widen the therapeutic index of MEK inhibitors.

213 se of iRGD coadministration as a strategy to widen the therapeutic window for HCC chemotherapy, as mo

214 advent of novel treatment strategies to help widen the therapeutic window for patients with oligometa

215 iers in the tumor microenvironment to safely widen the therapeutic window of a nanoformulated cytotox

216 This strategy aims to widen the use of PARPi in BRCA-competent and olaparib-re

217 To widen the utility of 5-aza-7-deazaguanine nucleosides, s

218 As convergence thickened and widened the Himalaya, the orographic barrier to precipit

219 Using this pipeline, we have widened the known antimicrobial spectrum for V. odorata

220 rn of the pericystic network of vessels, and widened the large lymphatics in Pkd1(nl/nl) mice.

221 conduction bands of CdS QDs and TiO(2) IOPCs widened the range of light absorption, allowing for elec

222 In the past decades, studies have widened the role of type-I interferons (IFNs) in disease

223 We have, therefore, widened the scope of analysis to include in vitro-induce

224 ed important insights into RNA structure and widened the scope of RNA studies.

225 e the convex geometry of the ceramic spheres widened the waterjet and reduced its velocity by two ord

226 as in fundamental soft condensed matter, by widening the accessibility of target regions in the phas

227 ncing, dedicated efforts are needed to avoid widening the already pervasive gap in health care dispar

228 d relatively hydrophilic polymeric molecules widening the applicability of the simple and cost-effect

229 PPMO) is deemed necessary to provide data in widening the applications as a niche products or raw mat

230 re transport of coastal water, substantially widening the area influenced by highly productive upwell

231 Widening the availability of bariatric surgery could lea

232 For widening the color spectrum and their usage, various bet

233 st range of risk for warfarin complications, widening the floor ceiling effects that limit the use of

234 anion-insertion potential in the anode, thus widening the full cell's voltage by 0.35 V compared with

235 side and warms the night-side, significantly widening the habitable zone.

236 atista movement of Chiapas, and we recommend widening the hypothesis space to include these alternati

237 Progressively widening the I(CaL,D-C) window region produced EADs of v

238 nd hits and differentiating their MoA, hence widening the known antibacterial chemical space of exist

239 embrane, displacing the paranodal myelin and widening the nodal gap.

240 s, leading to more effective coagulation and widening the pH range of water treatment.

241 and 3+ oxidation states, thus significantly widening the possible combinations of metals to replace

242 or adipocyte and energy expenditure biology, widening the potential of genetically supported therapeu

243 tween light- and heavy-hole valence bands by widening the principal band gap, which also results in a

244 early stages of drug discovery, whilst also widening the range of communities participating in the p

245 rticular is a compatible fabrication method, widening the range of electronic materials available and

246 nd reduced cooperativity of the process thus widening the response window.

247 y on 3-alkyl/aryl 2-oxindols as well thereby widening the scope even further.

248 mage-guided photothermal ablation of tumors, widening the scope of the NPs into the therapeutic realm

249 extraction and data preprocessing steps and widening the scope of valid downstream analyses.

250 of amides catalyzed by N-hydroxyphthalimide, widening the synthetic versatility of this process.

251 There is great interest in widening the use of high-sensitivity cardiac troponins f

252 We propose widening the view on immunoregulation by considering the

253 tion of Genome3D data into InterPro, thereby widening the visibility of both the annotation data and

254 waveform; (ii) to investigate the effects of widening the window I(CaL) on EAD-propensity; and (iii)

255 Widening the window I(CaL,D-C) , symmetrically by stepwi

256 Thus, the movement of one dynamic domain widens the active site entrance, while another domain ac

257 While H2A.Z widens the barrier, uH2B heightens it, and both modifica

258 This work widens the choice of water channel morphologies for wate

259 that blocking GABAergic signalling strongly widens the coincidence detection window of direct excita

260 Neuroadaptive technology significantly widens the communication bottleneck and has the potentia

261 sence of challenging ortho-substituents, and widens the currently available coupling space in oxidati

262 athway for strengthening eutectic alloys and widens the design toolbox for high-performance materials

263 While the formation of interphases widens the electrochemical window, their electronic and

264 ve step in in vivo imaging and analysis that widens the optical imaging window to the near-infrared s

265 support that artery-targeted photothrombosis widens the penumbra while maintaining the ability to cre

266 m/dementia with subclinical optic neuropathy widens the phenotypic spectrum of OPA1 mutations, highli

267 low H2 concentration and short growth times widens the possibility of industrial mass production.

268 f the repulsive exponent in the LJ potential widens the range of applicability and accuracy of MD sim

269 This greatly widens the range of applications for the cryogenically 3

270 hed that the use of derivatization reactions widens the scope of targeted molecules but also clearly

271 ations serving as a reserve source for acini widens the therapeutic options for hyposalivation.

272 we demonstrate that neonatal surgical injury widens the timing window during which correlated presyna

273 lar structures with spontaneous polarization widens the utility of facile supramolecular chemistry.

274 actions at elevated temperatures, which also widens the window of application to resins that are waxy

275 es should be incorporated into such tools to widen their appeal and improve their usability.

276 aterials could improve their versatility and widen their applicability in electronics and sensing.

277 status of these programs and how to further widen their implementation.

278 When close to prey, porpoises actively widen their sonar beam, which may make it harder for the

279 These progressively widen their territories until forming a uniform perisoma

280 The remaining ant species widened their diet breadth in a way that maintained seed

281 host response with a view to optimizing and widening their applications in higher organisms.

282 b, as negative modulators of the Hh pathway, widens their application in the context of NSCLC.

283 transcriptional amplification mechanism that widens their selective responses to low IL-2.

284 the amplitude of postsynaptic potentials and widens their temporal spread.

285 on of vestibular stereocilia and irregularly widened them.

286 As immunometabolic adjuvants to widen therapeutic windows, IDO inhibitors may leverage n

287 an translate to improved drug efficacy and a widened therapeutic window.

288 he neuron, but in recent years the focus has widened to also include other neural cells including ast

289 a and subsequent outcomes in England to help widen understanding for the global burden of hospitalisa

290 ociated with higher fracture risk because of widened, unstable bones, independently of BMD.

291 tter disturbances, thin corpus callosum, and widened ventricles); global delay with significant alter

292 Septal widening was a frequent, striking histological feature r

293 Unexpectedly septal widening was the only histological change detected in so

294 race and class, particularly in cities with widening wealth gaps.

295 d human fetal muscle myofibrils elongate and widen with age, but features such as the M-line and Z-ba

296 nger than LTL and the LTL-MTLA gap similarly widened with age in ASCVD patients and controls.

297 7 for men and from 2.3 to 4.0 for women) and widened with successive birth cohorts, particularly for

298 LPI resulted in angle widening with a significant increase in opening distance

299 ile the environmental and economic disparity widened within the region.

300 areas created upon damage by shallowing and widening wounds until healed.