ライフサイエンスコーパス: widespread

1 tropy and mean diffusivity were anatomically widespread.

2 Our data suggest widespread 2'3'-cGAMP signaling in insect antiviral immu

3 ntrast to traditional therapies that promote widespread ablation, emerging nano-strategies that speci

4 stages, its timely elimination will require widespread access to safe and effective radical cure.

5 Most studied inversions are widespread across continents, and their frequency is neg

6 Neanderthals were once widespread across Europe and western Asia.

7 n order Rhynchocephalia (Sphenodontia), once widespread across Gondwana(1,2)-is an iconic species tha

8 y living organisms via chemical reaction, is widespread across Metazoa.

9 g artemisinin-based combination therapy), is widespread across Southeast Asia but to date has not bee

10 Our approach reveals that cis effects are widespread across transcribed regulatory elements, and t

11 alysing trait data within a context of three widespread, adaptive life-history strategies-sexual dich

12 However, its widespread adoption for gunshot injuries has been sluggi

13 However, their widespread adoption has lagged behind Cas9-based strateg

14 arts are key technological obstacles for the widespread adoption of additive manufacturing (AM).

15 The widespread adoption of high throughput technologies has

16 Here, we examine the widespread adoption of low-energy precision application

17 Despite the widespread adoption of organoids as biomimetic tissue mo

18 rt Association, we provide rationale for the widespread adoption of rapid diet screener tools in prim

19 Widespread adoption of rapid genomic testing in pediatri

20 Based on these insights, we call for widespread adoption of the homologous nomenclature, and

21 ded growers new options to manage weeds, the widespread adoption of these herbicides increased the ri

22 ing mechanochemical reactivity, enabling its widespread adoption to support the developing field of p

23 We found that knockdown of CYP2J2 elicits widespread alterations in gene expression of ventricular

24 heral injury, and stroke patients experience widespread alterations in neural activity after sensory

25 study of 22q11DS to date, the authors found widespread alterations to subcortical brain structures,

26 Additionally, we report that prophages are widespread among oral-associated TM7, while absent from

27 esearch shows that distrust of the police is widespread and consequential for public safety.

28 ressure exerted by bed nets has precipitated widespread and escalating resistance to pyrethroids in A

29 r- and polyfluoroalkyl substances (PFAS) are widespread and persistent pollutants that have been show

30 that the active population demonstrated more widespread and robust changes.

31 The association between the widespread and significant nitrogen (N(2) )-fixing cyano

32 ps and variation profiles visually exhibited widespread and substantial differences in EGS use and mo

33 adoption of such policies has yet to become widespread and uniform.

34 hat convergence at the genetic level is also widespread, and can be caused by either (i) parallel gen

35 f bacterial CRISPR arrays, and we identify a widespread antitermination mechanism that antagonizes Rh

36 A key underlying factor of their widespread applicability is the degree of control that c

37 ng this new approach (R package "NobBS") for widespread application and provide practical guidance on

38 Our findings open the door for the widespread application of nanographenes in super-resolut

39 Widespread application of neonicotinoids has led to thei

40 Despite the widespread application of viral- and non-viral-mediated

41 ently bind macromolecular targets have found widespread applications as activity-based probes and as

42 TAEs have widespread applications in material science and supramol

43 inevitably promote the rapid development and widespread applications of next-generation wearable elec

44 yclic host cucurbit[7]uril (CB[7]), enabling widespread applications, but hindering CB[7] materials f

45 hat trees would have reached critical PLC in widespread areas (i.e. it projected a low mortality risk

46 Sodium-ion batteries have captured widespread attention for grid-scale energy storage owing

47 I/UBP14) leads to reduced auxin response and widespread auxin-related phenotypic defects in Arabidops

48 cytosis to the healthy brain, a mechanism of widespread BBB dysfunction with age and a strategy for e

49 Widespread belief in misinformation circulating online i

50 ent meta-analytic findings and challenge the widespread belief that caregiving is a substantial risk

51 vo binding to sog_Distal but also identified widespread binding throughout the genome, comparable to

52 acterial species, and Pel may therefore be a widespread biofilm determinant.

53 leri shared only two unique traits each with widespread boreal-Arctic R. palpebrosa.

54 istorically observed tolerances help explain widespread bumble bee species decline.

55 We demonstrate widespread Capn15 expression throughout the brain and ce

56 (ZIKV) has caused significant disease, with widespread cases of neurological pathology and congenita

57 We identified widespread cell-type-enriched aging and genetic effects

58 H3K27M functions, at least in part, through widespread changes in H3K27 trimethylation but its role

59 dwelling individuals, acute exercise elicits widespread changes in the circulating metabolome.

60 ons, we observed that fungal partners caused widespread changes in the fitness of bacterial mutants c

61 ctor kappaB (NF-kappaB) and TCF3, as well as widespread changes in the transcriptional output of LMP2

62 ependent of the disease stage or presence of widespread changes on autofluorescence widefield images.

63 MRI studies show that widespread changes to brain networks contribute to cogni

64 Widespread changes to DNA methylation and chromatin are

65 es of disease-causing mutations, and observe widespread chemical shift perturbations for methyl group

66 recent progress and remaining challenges for widespread clinical implementation of nanomaterials as a

67 ts, but key challenges have restricted their widespread clinical use outside of certain dermatologica

68 Widespread community transmission has triggered stringen

69 The mammalian claustrum, owing to its widespread connectivity with other forebrain structures,

70 The widespread consensus argues that the emergence of abstra

71 In the literature, there is widespread consensus that methods in plastic research ne

72 eed, multiple SAS subfamilies are encoded in widespread conserved bicistronic operon architectures th

73 Although widespread convergence of animal phenotypes to their nat

74 Despite widespread conversion, roughly 1.2 billion ha of tropica

75 arly driver mutations in RAS and KIT and the widespread copy number events by which TGCT is character

76 disorders exhibit altered brain networks in widespread cortical and subcortical regions.

77 AV-1451 uptake in all disease groups, across widespread cortical regions.

78 The widespread crisis of plastic pollution demands discovery

79 ion and downstream analyses without inducing widespread damage to the DNA.

80 ivation in the epithelia, accompanied with a widespread decidualization feature in the stromal fibrob

81 on of environmental disturbances has sparked widespread decline and compositional shifts in foundatio

82 undance of Pseudogymnoascus roseus, the most widespread decomposer fungus in maritime Antarctic fellf

83 of the GALC-deficient mouse (Twitcher), and widespread deletion of GALCLAMP1 recapitulates the Twitc

84 cial learning capabilities are taxonomically widespread, demonstrating that freely interacting animal

85 uctural racism in scientific funding and the widespread denial of its existence.

86 of complement-mediated inflammation revealed widespread deposition of complement-activation fragments

87 017 nuclear release of ruthenium that led to widespread detections of the radioisotope (106)Ru in the

88 e sources of GABAergic projections were more widespread, displayed a high degree of differential inne

89 virus-1 (HSV-1), and cellular stresses cause widespread disruption of transcription termination (DoTT

90 glucose metabolism, cognitive impairment and widespread disruption of WM structure occur in an early

91 However, the widespread distribution of MeCP2 suggests it has additio

92 Given the widespread distribution of these channels, ion channel f

93 Despite widespread diversity in behavior and its motor control,

94 Consequently, a widespread down-regulation of chromatin accessibility oc

95 Glioblastoma might have widespread effects on the neural organization and cognit

96 Climate change is leading to widespread elevational shifts thought to increase specie

97 Further, BGRD displays widespread enrichment of repressed cis-regulatory elemen

98 Eutrophication is a widespread environmental change that usually reduces the

99 Perfluorohexane sulfonate (PFHxS) is a widespread environmental contaminant found in human seru

100 a diverse class of industrial chemicals with widespread environmental occurrence.

101 The newly identified and widespread epigenetic marker 6mA DNA methylation is asso

102 cesses with partial nitrification is already widespread, especially for sidestream treatment, maintai

103 In contrast to widespread examples of phenotypic evolution driven by in

104 Our analysis suggests that the widespread expansion of humans through North America was

105 ChIP-Seq is a widespread experimental method for determining the globa

106 , given the high pediatric asthma burden and widespread exposure to BPA in the United States.

107 ral window for cone genesis and, given their widespread expression in the nervous system, raise the p

108 interventions that will be needed to prevent widespread extinction in this group in coming decades.

109 heat-shock proteins (sHsps) compose the most widespread family of molecular chaperones.

110 ival in planta Kiwellin (KWL) proteins are a widespread family of plant-defense proteins that target

111 is poised to increase in the tropics, where widespread food insecurity persists and increased agricu

112 es of antigen receptor V-regions may be more widespread, for example, inducing states of preparedness

113 Iridescence is a striking and taxonomically widespread form of animal coloration [1], but that its i

114 We observed widespread gene expression in, central and peripheral ne

115 where Wnt/beta-catenin signaling drives both widespread gene repression and activation.

116 The fauna of Russia primarily includes widespread generalist species that are here considered L

117 More broadly, we identified widespread genomic signatures of runaway transcription i

118 ific and technological advances have enabled widespread genotyping efforts and dynamic research in th

119 cally diverse antibiotic-resistant lineages, widespread geographical mixing, and frequent recombinati

120 om two CYLD p.M719V mutation carriers showed widespread glial CYLD immunoreactivity.

121 er arthropod-transmitted viruses represent a widespread global health problem, with limited treatment

122 Although widespread group differences were seen across the cortex

123 a defense metabolite that is one of the most widespread GSLs in Brassicaceae and has also been associ

124 ds, will have already undergone repeated and widespread heat wave induced degradation.

125 Widespread heterogeneity of results from studies publish

126 Rapid warming in the Arctic is leading to widespread heterogeneous shrub expansion, but impacts of

127 Widespread higher radial diffusivity (RD) was also obser

128 ive of the past several million years before widespread human-driven extinctions.

129 cal outcomes and prioritise management among widespread human-induced behavioural shifts, while also

130 a demonstrate that mammalian STING possesses widespread IFN-independent activities that are important

131 ell proliferation before progressing to more widespread immune dysregulation.

132 mber variants (CNVs) are suggested to have a widespread impact on the human genome and phenotypes.

133 provide a mechanistic explanation for Lon's widespread impact.

134 The widespread implementation of fluorescence in situ hybrid

135 Despite the widespread implementation of public health measures, cor

136 syndrome coronavirus 2 has led to rapid and widespread implementation of seroprevalence studies.

137 are derived in vivo, and thus this work has widespread implications for understanding the mechanisms

138 the polysaccharide polysialic acid (PSA) has widespread implications in physiological and pathologica

139 erconnectivity, a counterintuitive result of widespread importance across the physical, life, and soc

140 instead posit that ecological change favored widespread improvements in male provisioning incentives,

141 Widespread improvements in treatment as prevention and g

142 red bifunctional oxygen-independent pathway, widespread in bacteria, salvages at least two by-product

143 solution microscopy is becoming increasingly widespread in biological labs.

144 c (M) (CytM), a cryptic c-type heme protein widespread in cyanobacteria.

145 rminal repeat (LTR) retroelements, which are widespread in eukaryotic genomes but recalcitrant to aut

146 Whereas CC151, CC97 were widespread in Europe, CC479, CC398 and CC8 were only fou

147 Petal pigmentation patterning is widespread in flowering plants.

148 CTX-M beta-lactamases are widespread in Gram-negative bacterial pathogens and prov

149 prokaryotic cytoskeletal constituent that is widespread in magnetic and nonmagnetic spirilla-shaped A

150 cardiogram (ECG) acquisition is increasingly widespread in medical and commercial devices, necessitat

151 confounding due to linkage disequilibrium is widespread in naive phenome-wide association studies of

152 Multi-species microbial communities are widespread in natural ecosystems.

153 Genetic interactions such as epistasis are widespread in nature and can shape evolutionary dynamics

154 l intracellular symbiosis (endosymbiosis) is widespread in nature and impacts many biological process

155 nction mutations are positively selected and widespread in nature, making them a powerful tool to stu

156 unction to behavior, and its use is becoming widespread in neuroscience.

157 5-methyl cytosine is widespread in plant genomes in both CG and non-CG contex

158 Tissue cell polarity is widespread in plants and can influence how cells grow, d

159 ll 'information limitation', is likely to be widespread in real ecological systems and can dictate bo

160 This phenomenon may be widespread in ssDNA viruses that simultaneously synthesi

161 Masting is particularly widespread in temperate trees [8, 9] impacting food webs

162 Ecologically relevant symbioses are widespread in terrestrial arthropods but based on recent

163 - and polyfluoroalkyl substances (PFASs) are widespread in the blood of the general human population,

164 adaptation to changes in visual contrast is widespread in the early Drosophila visual system, improv

165 r of neuronal excitability is proposed to be widespread in the nervous system.

166 , suggesting that occasional tool use may be widespread in this group, and that seabirds' physical co

167 addition to confirming that P limitation is widespread in tropical regions, our study demonstrates t

168 ther, these findings indicate no evidence of widespread inappropriate methods to improve performance

169 We find a widespread increase in cytosine modifications at enhance

170 We observe widespread increases in chromatin accessibility at retro

171 subthreshold depolarizations of B21 produce widespread increases in its [Ca(2+)](i) via activation o

172 ctive within the SCID mouse brain and showed widespread infection of normal brain cells.

173 aggregation are features of HAM, reflecting widespread inflammatory change, which may be detectable

174 ns how hyperpolarizing a hub cell results in widespread inhibition of islet electrical activity and d

175 iological features enabling them to impart a widespread inhibitory influence on neural activity.

176 ine and chloroquine, have recently attracted widespread interest as potential therapies for coronavir

177 There is widespread interest in programs aiming to reduce spendin

178 porous metal-organic networks have attracted widespread interest owing to their potential application

179 pically reside outside of exons has inspired widespread investigation into the genetic basis of trans

180 d by active granulomatous encephalitis, with widespread involvement of other organs.

181 temperate rocky reefs, this has resulted in widespread kelp deforestation and the formation of sea u

182 ticular are global public health issues with widespread, lasting impacts on children, families, and c

183 Lastly, embryos lacking opa exhibit widespread, late patterning defects spanning both axes.

184 Cannabis usage is increasing with its widespread legalization.

185 significantly increased axial diffusivity in widespread locations, demonstrating white matter changes

186 Widespread long cracks and the evidence of relevant mass

187 We find that FUS-ALS mutations induce a widespread loss of function on expression and splicing.

188 ns from saprotrophy to symbiosis involve (1) widespread losses of degrading enzymes acting on lignin

189 We observed subtle, but widespread, lower fractional anisotropy (FA) in adult MD

190 Modelling supports the idea that widespread marine anoxia was induced by a greenhouse-dri

191 Wallerian degeneration is a widespread mechanism of programmed axon degeneration.

192 Here, we describe a widespread mechanism promoting 3' US in cancer through u

193 Translational control is a widespread mechanism that allows the cell to rapidly mod

194 Lonicera japonica is a widespread member of the Caprifoliaceae (honeysuckle) fa

195 teria, and considering the looming crisis of widespread microbial drug resistance it is an attractive

196 confines of the crypt are rare, we observed widespread millimeter-scale clonal expansions.

197 Cytosine methylation of DNA is a widespread modification of DNA that plays numerous criti

198 est that migratory behavior does not require widespread modifications of brain structure, but might b

199 subject of uniquely long-term and spatially widespread monitoring effort in Scotland, where it breed

200 to local circumstances elsewhere to prevent widespread mortality in indigenous communities.

201 g thousands of infected patients and causing widespread mortality.

202 Asthma is a widespread, multifactorial chronic airway disease.

203 Fibromyalgia is characterized by chronic, widespread musculoskeletal pain and associated fatigue,

204 res, mechanisms, and evolutionary origins of widespread Na(+)-coupled transporters.

205 structural damage at the site of injury, and widespread network dysfunction caused by structural, fun

206 difies different oscillatory activities in a widespread network of cortical and subcortical regions.

207 nockdown of GDPGP1 in mouse neurons leads to widespread neuronal cell death.

208 cted creeks of the U.S. West Coast indicated widespread occurrence of 6PPD-quinone (<0.3 to 19 microg

209 inated community, potentially explaining the widespread occurrence of Vibrio in surface-ripened chees

210 n adaptive explanation for its taxonomically widespread occurrence.

211 a within natural beachrock biofilms that are widespread on (sub)tropical coastlines.

212 Attribution was widespread, originating at 17 of 20 ACHs (85%), 7 of 8 (

213 In 2015 and 2016, Colombia had a widespread outbreak of Zika virus.

214 gatively related to resource C:P, indicating widespread P limitation in these detritus-based food web

215 near future, bringing new prospects for the widespread penetration of renewables and extensive power

216 r- and polyfluoroalkyl substances (PFAS) are widespread persistent organic pollutants and endocrine d

217 in California following a 4-year drought and widespread pest outbreaks.

218 enhanced cooperativity demonstrates how the widespread phenomenon of enzyme polymerization can be ad

219 Drought-related tree mortality is now a widespread phenomenon predicted to increase in magnitude

220 opportunities to explore the role of IR as a widespread phenomenon that contributes to the transcript

221 he colonization of surfaces by bacteria is a widespread phenomenon with consequences on environmental

222 Although a widespread phenomenon, definitive functions for endogeno

223 Our findings demonstrate widespread pleiotropy and offer further insight into the

224 The results suggest that widespread pollution in tropical regions may result in h

225 We found widespread positive selection in 17 genes.

226 rd ascribing regulatory significance to this widespread post-translational modification.

227 A-to-I editing of RNA is a widespread posttranscriptional process that has recently

228 hat thymine-rich intergenic regions harbor a widespread potential to produce transmembrane domains.

229 n language to text, have become increasingly widespread, powering popular virtual assistants, facilit

230 ic waste (OW) as fertilizer on farmland is a widespread practice that fosters sustainable development

231 orpholino oligonucleotides (U1 AMO) triggers widespread premature transcription termination and mRNA

232 ving research attention as a result of their widespread presence in effluents and wastewater treatmen

233 Given the widespread presence of hflX genes, we anticipate this as

234 s and the ribosomal methyltransferases whose widespread presence severely compromises all aminoglycos

235 he long-lived Pu'u 'O'o eruption site caused widespread pressurization in the volcano, driving magma

236 Despite the widespread programmatic implementation of reactive strat

237 Here, we report that widespread promoter-proximal RNA polymerase II pausing i

238 Although R-DPRs induce widespread protein aggregation in this in vitro system,

239 hough unsuitable as biological probes due to widespread reactivity, dienone compounds are cytotoxic t

240 We report widespread, recurrent, and functionally relevant 3'-UTR

241 hanistically, PADI4 inhibition resulted in a widespread redistribution of histone H3, with increased

242 and molecular dynamics simulations indicated widespread redox regulation of cryptic cysteine residues

243 white matter alterations as demonstrated by widespread reduction in fractional anisotropy (FA) based

244 Patients showed a widespread reduction of spindle density and, in both gro

245 the ENIGMA-DTI working group, we identified widespread reductions in mean, axial and radial diffusiv

246 acellular glutamate transient recording over widespread regions of mice dorsal neocortex in relation

247 ction by plant populations, or masting, is a widespread reproductive strategy in long-lived plants.

248 The widespread resistance to Cry1 and Cry2 proteins in H. ze

249 Most current therapeutics suffer from widespread resistance, creating a need for new drug targ

250 Inter-episode boundaries evoked a widespread response at episode onset, plus a marked offs

251 station of subalpine environments and caused widespread rewilding.

252 Surprisingly, whereas increases were due to widespread sea ice loss during the first decade, the sub

253 Widespread seafloor methane venting has been reported in

254 Cyclic diadenylate (c-di-AMP) is a widespread second messenger in bacteria and archaea that

255 y to climate change, even for geographically widespread species.

256 tics, or neuroinflammation in ASD, alongside widespread starkly atypical moderating effects of age, s

257 Neural networks enjoy widespread success in both research and industry and, wi

258 Widespread testing and infection control are key to help

259 Widespread testing for the presence of the novel coronav

260 vity among pharyngeal neurons, which is more widespread than previously realized, the sensory-motor c

261 How widespread these mechanisms are among vertebrates essent

262 evidence for an evolutionary reversal from a widespread to restricted trichome distribution involving

263 tion and secretion during pregnancy, elicits widespread transcript shortening through APA in 3'UTRs a

264 and a subset of mCG sites resulting in more widespread transcriptional alterations and severe neurol

265 Rapid and widespread transmission of SARS-CoV-2 was demonstrated i

266 m onset, an unusual feature that has enabled widespread transmission of the virus and precipitated a

267 in agricultural land conversion may lead to widespread trophic cascades and in some cases irreversib

268 ncreased and resulted in cytoplasmic TDP-43, widespread ubiquitination, and cortical and hippocampal

269 on the published health analysis of PR, the widespread UOGD could induce adverse health effects to r

270 ycosides (SGs) has prevented their potential widespread usage as non-nutritional high intensity sweet

271 assed since the introduction of lithium into widespread use at the birth of modern psychopharmacology

272 echnology, droplets on solid surfaces are of widespread use for handling small amounts of matter, for

273 Its widespread use has been hampered due to concerns about n

274 ng donor liver transplantation (LDLT) enjoys widespread use in Asia, but remains limited to a handful

275 Photoactivated materials have found widespread use in biological and medical applications an

276 Despite its widespread use in oncology, the PET radiotracer (18)F-FD

277 n impractical lab model and has prevented it widespread use in research.

278 Despite widespread use in the management of newborns with CDH, E

279 The widespread use of controlled release systems is hindered

280 Despite reported widespread use of dietary supplements during cancer trea

281 analysis of the most interesting strains and widespread use of droplet technologies in analytical mic

282 erse experimental conditions has enabled the widespread use of gene co-expression network (GCN) analy

283 Widespread use of gene therapy technologies is limited i

284 (CRPC), is increasing in incidence with the widespread use of highly potent androgen receptor (AR)-p

285 Despite widespread use of immunomodulatory therapies, patients m

286 Despite the widespread use of initial rate determination for process

287 The widespread use of strong or poorly soluble inorganic bas

288 lementation strategies are needed to achieve widespread use of these life-saving medications.

289 Widespread use of these medications forced overwhelmed h

290 Despite the widespread use of this model, the mechanisms that underl

291 Despite widespread use, however, lamivudine triphosphate (3TC-TP

292 Despite the widespread use, only sparse information is available on

293 iew explores the properties that led to such widespread use, why there is now an increasing drive to

294 ut each possesses limitations that constrain widespread use.

295 lti-component semi-solid emulsions that find widespread utility across a wide range of pharmaceutical

296 or 1,3-dipolar cycloaddition reactions is of widespread utility in chemistry.

297 ccine serotypes (NVT) was observed following widespread vaccine uptake.

298 Subtype 1 displayed widespread volume reduction correlating with illness dur

299 changes in neuronal network activity trigger widespread waves of extracellular GABA in hippocampal ne

300 izophrenia has recently been associated with widespread white matter microstructural abnormalities, b