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1 tial amplitude in peripheral mouse C-fibres (wildtype).
2 G mutant were similar to those obtained with wildtype.
3 reduced selectivity for Ca(2+) compared with wildtype.
4 expression between fiberless mutant and its wildtype.
5 afety) in the order Nav 1.8 KO > Nav 1.9KO > wildtype.
6 ical constriction in acellular embryos as in wildtype.
7 iation was only retained in astrocytoma, IDH-wildtype.
8 , and in a short day photoperiod compared to wildtype.
9 d prognostic information in astrocytoma, IDH-wildtype.
10 fold higher in the N408K mutant, than in the wildtype.
11 ypes between heterozygotes, homozygotes, and wildtypes.
12 aptive substitutions, but poorly neutralized wildtype 2019-2020 A/Kansas/14/2017 (H3N2) HA-pseudoviru
14 gnificantly higher activation rates than the wildtype (90-fold versus 20-fold) and interacted with an
19 2 Arabidopsis shoot architectures, including wildtype and 10 mutant strains, and we uncovered a desig
20 d high-throughput phenotype data from 14,250 wildtype and 40,192 mutant mice (representing 2,186 knoc
27 ed CB2R mRNA expression in VTA DA neurons in wildtype and DAT-Cnr2 cKO heterozygous but not in the ho
28 and recovery, we generated littermate PVG C6 wildtype and deficient rats and tested functional and hi
29 to differential footpad DTH responses using wildtype and four core genotypes (FCG) mice and poplitea
30 to potential mechanistic differences between wildtype and FTDP-17 Tau variants, as well as different
31 was prevented by a GluN2C/2D potentiator in wildtype and GluN2C heterozygous mice but not in GluN2C
34 h no significant difference observed between wildtype and heterozygous patients in the majority of th
39 n human atrial myocardium and in both intact wildtype and M2 or M1/3-receptor knockout mouse Langendo
40 dianion binding to the transition state for wildtype and many mutant TIM-catalyzed reactions of subs
41 istribution and brain PET imaging studies in wildtype and mGluR2 knockout rats in a primate and in hu
43 detergent-resistant membrane fractions from wildtype and mutant cells, consistent with the predictio
44 r understanding RTT pathophysiology, wherein wildtype and mutant neurons are intermixed throughout th
46 comparison of rNTP incorporation kinetics by wildtype and mutant Pol mu indicates that rNTP accommoda
48 tatively recapitulates branching of cultured wildtype and mutant ureteric buds, and achieves similar
52 nstrated tumor growth inhibition in both p53 wildtype and p53 mutant cancer cell lines, demonstrating
57 ation of APAP evoked a marked hypothermia in wildtype and Trpv1(-/-) mice, but only restored normal b
58 atellite stable/MSI-low, CIMP-negative, BRAF-wildtype, and KRAS-wildtype tumors (P (trend) range from
59 of SBMA, a myogenic model that overexpresses wildtype androgen receptor (AR) exclusively in muscle fi
61 lagl1 and Sox9 did not induce gliogenesis in wildtype animals, but nonetheless activated expression o
62 CD electroporation, inhibited gliogenesis in wildtype animals, but rescued MG development in Lhx2-def
66 of the red-shifted protein from that of the wildtype are observed by Fourier transform infrared spec
71 ding of the mutant was nearly similar to the wildtype; binding of Mg2+ occurred with higher affinity.
73 trongly associated with tumors that are KRAS wildtype, BRAF wildtype, have no or a low CpG island met
79 mical experiments demonstrate the binding of wildtype but not mutant E2F promoters by repressive PRC1
84 w that the modified Prox-1-GFP mice carrying wildtype C57BL/6 background provide a valuable tool for
85 Ad5.TGFbeta2 induced ocular hypertension in wildtype C57BL/6J mice and further amplified the IOP in
86 id ccm strain increased 121% relative to the wildtype ccm strain, with an electron flux per cell of 1
88 e observed a strong expression of MT1-MMP in wildtype cells of both primary tumors and lung metastase
89 moderate inhibition of PI3K-AKT signaling in wildtype cells was sufficient to cause AJ alterations.
91 cells were longer and more flagellated than wildtype cells, which may explain their predominance on
95 Phosphorylation-dependent potentiation of wildtype CFTR and other variants also was observed in ep
97 tein carrying the T303E mutation but not the wildtype claudin-16 or the T303R mutant protein increase
99 distinguished pathogenic TNNT2 variants from wildtype controls using a sarcomere functional reporter
100 hese mice displayed lower pH in neurons than wildtype controls, determined by intracellular pH in hip
102 remarkably lower in Keap1(f/f) pups than in wildtype counterparts (28.9% vs 2.4%, wildtype vs Keap1(
104 1.22, 1.99; Pheterogeneity = 0.04), and KRAS-wildtype CRC (OR per 5 kg/m2: 1.35; 95% CI: 1.17, 1.54;
105 3H/HeJ mice were sensitized with recombinant wildtype Cyp c 1 or carp extract by intragastric gavage.
106 proliferation experiments using recombinant wildtype Cyp c 1, and overlapping peptides spanning the
108 hat crypts (one or two) are a normal part of wildtype development but they almost all resolve by birt
114 bsequently, we showed that C. jejuni 81-176 (wildtype) exhibited enhanced chemoattraction to and resp
115 could follow the double pulsed stimulus with wildtype fibres blocking first and Nav 1.8 KO fibres end
118 obal gene expression patterns in livers from wildtype, Gcn2 (-/-), and Atf4 (-/-) mice treated with a
120 rkB receptors mimics the MeCP2 deficiency in wildtype glutamatergic neurons, while re-expression of B
122 rotection from cisplatin that was similar to wildtype GRK2, suggesting that this protection may be me
124 ted with tumors that are KRAS wildtype, BRAF wildtype, have no or a low CpG island methylator phenoty
125 eles was compared as well as those that were wildtype, heterozygous, or homozygous for the TSLPrs1898
126 GS(double dagger))GA+HPi = 3.3 kcal/mol, for wildtype hlGPDH-catalyzed reaction of GA + HPi, and for
127 lues of kcat/KGAKX for dianion activation of wildtype hlGPDH-catalyzed reduction of GA and kcat/KGAKX
128 ents with superior therapeutic efficacy over wildtype hMSCs in the diabetic mouse model without repla
131 e time points through retransplantation into wildtype hosts mediates B cell recruitment into lymphoid
132 sociated virus pseudotype 2/5 to overexpress wildtype human alpha-synuclein (rAAV2/5 alpha-syn).
135 ng fibres in knockout animals as compared to wildtypes, in combination with reduced per-pulse sodium
138 stituted beta-hairpin PriA variant displayed wildtype levels of DNA unwinding and PriB binding in vit
141 king the IDR (DeltaIDR prestin) demonstrated wildtype-like nonlinear capacitance (NLC) in HEK293T cel
143 -)) mice gained less body weight compared to wildtype littermate control (M-JAK2(+/+)) mice and were
148 umor suppressor gene in TUSC2 deficient EGFR wildtype lung cancer cells increased sensitivity to erlo
149 acle for fertilisation is similar for SR and wildtype male sperm, both over short and long time-frame
151 ge in type I IFN receptor-deficient mice and wildtype mice administered neutralizing Abs against type
152 d the effects of environmental enrichment in wildtype mice and in a mouse model of Abeta neuropatholo
153 posterior tissues isolated from Fkbp8-/- and wildtype mice at E9.5 and E10.5 showed that Fkbp8-/- emb
156 his study we used FMR1 knockout and isogenic wildtype mice to systematically map the distribution of
158 e cranial base of newborn Pax7-deficient and wildtype mice using a computational shape modeling techn
159 the study of D1-MSN dendrite development in wildtype mice, and its degeneration in a mouse model of
160 ene was sexually differentially expressed in wildtype mice, glycosylation-dependent cell adhesion mol
163 reased angiotensin II responsiveness only in wildtype mice, which coincided with decreased AT1 contri
179 ated by these mutations, is expressed at the wildtype Michaelis complex, and ca. 50% is only expresse
182 e, increased with ex-vivo phosphorylation of wildtype mouse bones and declined with ex-vivo dephospho
186 y cages, APPSWE /PS1dE9 (n = 27) and healthy wildtype (n = 21) mice were randomly assigned to either
187 erse group of minimally permeant cations for wildtype NaChBac, ranging in sizes from ammonium to guan
188 idine have much less effect on the growth of wildtype neural stem cells and Prospero neural tumours.
189 BDNF acts cell autonomous and autocrine, as wildtype neurons are not capable of rescuing growth defi
191 ations in KRAS [KRAS wildtype] or BRAF [BRAF wildtype], no or a low CpG island methylator phenotype,
194 fects of the novel variant, we expressed the wildtype or mutant hEAAT1 in mammalian cells and perform
195 ignalling axis promotes resistance on a TP53 wildtype or null background, but not a mutant TP53 backg
197 ne residue, is severely impaired compared to wildtype or the mutant viruses encoding K77R or K113R.
198 ippocampal neurons expressing Cre and either wildtype, or mutants mimicking or preventing phosphoryla
199 lecular subtypes (no mutations in KRAS [KRAS wildtype] or BRAF [BRAF wildtype], no or a low CpG islan
200 ction, high risk p53 mutation (p53HRmut) and wildtype p53 (p53WT) inactivated by the human papillomav
201 ese mutant p53 (mutp53) either directly lose wildtype p53 (wtp53) tumor suppressor function or exhibi
203 discoveries is critical because, while PTEN wildtype patients can be diagnosed clinically, they do n
207 d higher DET current values than that of the wildtype Pcyb-AfGDH-immobilized electrodes at pH 6.5, wh
208 s showed that repeated rounds of swarming by wildtype Pf-5 drives the accumulation of gacS/gacA spont
209 inate on the edge and that initial DeltagacA:wildtype Pf-5 ratios of at least 2:1 lead to a collapse
213 w reduced growth and seed yields relative to wildtype plants in fluctuating light and/or temperature.
215 g [Ca(2+)] at normal resting levels while in wildtype PNs mGluR1 EPSCs are enhanced by elevated [Ca(2
218 , importantly, all appear to destabilise the wildtype protein in co-transfection experiments in a hum
226 ed in recently available mGluR2 knockout and wildtype rats and in a monkey using a structurally disti
227 riments in Wistar and in mGluR2 knockout and wildtype rats as well as in vivo biodistribution and bra
231 s81-Mms4 to M phase but not S phase allows a wildtype response to various forms of replication pertur
237 rger increases in the activation barrier for wildtype ScOMPDC-catalyzed deuterium exchange compared w
240 far exceeding those inhibiting growth of the wildtype strain, even in the presence of the enzyme inhi
246 f substrate pieces shows that ca. 50% of the wildtype TIM dianion binding energy, eliminated by these
250 -low, CIMP-negative, BRAF-wildtype, and KRAS-wildtype tumors (P (trend) range from 0.03 to 3.4e-03),
251 onfidence interval, 0.65-1.04)] but not BRAF-wildtype tumors [1.09 (0.97-1.22); P difference as shown
253 MERS-CoV were resistant to superinfection by wildtype virus, likely due to reduced levels of the viru
255 eared in the order NaV 1.8 KO > NaV 1.9 KO > wildtype, which is most likely explained by the relative
256 metic dCENP-A mutants is reduced relative to wildtype, while non-phosphorylatable dCENP-A retention i
258 e cyanobacterium Synechocystis sp. PCC 6803 (wildtype) with alanine, present in higher plants, or wit
259 ic Hedgehog TP53-mutant, Sonic Hedgehog TP53-wildtype, WNT, Group 3, and Group 4, defined by the Worl
260 set specific (NS)-Pten heterozygous (HT) and wildtype (WT) adult mice received either intraperitoneal
264 ble cell lines expressing fluorescent-tagged wildtype (WT) and E22G Abeta42 to study the aggregation
266 tely high fat plus cholesterol diet (HFC)-on wildtype (WT) and liver-specific Foxo1/3/4 triple knocko
269 NH encoded by HAE-causing SERPING1 acts upon wildtype (WT) C1INH in a dominant-negative manner and fo
274 imilar substrate affinity (Km) values to the wildtype (WT) Km value but had a lower turnover number a
275 erozygous knockout (Foxp2+/-) mice and their wildtype (WT) littermates from juvenile to adult ages, a
276 s disease (AD)-like transgenic (Tg) mice and wildtype (WT) littermates with a single, whole-body dose
281 -USP20 was significantly increased in LVs of wildtype (WT) mice after a 1-week catecholamine infusion
282 was isolated from p58(IPK) knockout (KO) and wildtype (WT) mice and treated with lipopolysaccharide (
283 ment reduced plasma LDL-C, TC and TG in LDLR wildtype (WT) mice fed a high fat and high cholesterol d
287 of HPbetaCD resulted in OHC death in prestin wildtype (WT) mice whereas OHCs were largely spared in p
288 They have extended lifespans compared to wildtype (WT) mice, and male mice show enhanced fecundit
289 l age-related microbiome changes compared to wildtype (WT) mice, including an increase in Bacteroides
291 cles display the same number of myofibers as wildtype (WT) muscles, but by E18.5 dyW-/- muscles are s
292 , mediated prominent 2-APB-induced Ip on the wildtype (WT) Orai1 channels of narrow pore sizes, while
293 um vulgare L. cv Optic) mutant (NRH) and its wildtype (WT) parent were grown in tubes of sieved (<250
296 vity was monitored in cells transfected with wildtype (WT), Cys42Ser or Cys117/195Ser PKGIalpha that
298 tegrin, we compared the sterol dependence of wildtype Y. pseudotuberculosis internalization with that
299 MS), we analysed the retina of adult longfin wildtype zebrafish at 0, 3 and 18 days after Ouabain inj