ライフサイエンスコーパス: withdraw

1 recurrence occurs frequently once these are withdrawn.

2 endent rats but had bidirectional effects in withdrawn.

3 chieved HBsAg loss and in whom treatment was withdrawn.

4 ect in the 8-weeks fluorometholone group was withdrawn.

5 laced to after 21.00 hours rather than being withdrawn.

6 icipants and 28.4% of black participants had withdrawn.

7 uroblasts exit cell cycle when nutrients are withdrawn.

8 chieved HBsAg loss and in whom treatment was withdrawn.

9 The duplicate article has therefore been withdrawn.

10 ic overdose of signaling if the inhibitor is withdrawn.

11 d a distal one is favored when R is electron-withdrawing.

12 y activated microglia, and the inhibitor was withdrawn 1-week later to allow for microglial repopulat

13 Electron withdrawing 3,5-disubstituted pyridone ligands were iden

14 group, of 57 participants who did not die or withdraw, 30 (52%) advanced to step 2, and 17 (57%) of 3

15 to good yields for arenes carrying electron-withdrawing (50-85%) or weakly electron-donating groups

16 Hemorrhagic shock was induced in rats by withdrawing 60% of the blood volume and maintaining a hy

17 f more electronegative phosphorus atoms that withdraw a small charge from Ni ensembles results in dif

18 poly(3-hexylthiophene) owing to the electron-withdrawing ability of the aryl ketone side chains.

19 ationalized in terms of the greater electron-withdrawing ability of the azides in the pseudaminic aci

20 The electron-withdrawing ability of the protecting groups, but not bu

21 erstood in terms of the electron donating or withdrawing ability of the substituent.

22 In 12 cases, therapy was actively withdrawn according to patient's will.

23 3LS, and one participant in group 6 chose to withdraw after a single administration.

24 ar follow-up, with one patient in each group withdrawing after surgery (per-protocol population).

25 of JIA-U did not persist when adalimumab was withdrawn after 1-2 years of treatment.

26 tients (50%) had extracorporeal life support withdrawn after 6.7 +/- 3.6 days and were discharged aft

27 tners will likely be drawn upon when bOPV is withdrawn after polio eradication but also could be rele

28 y be drawn upon when all OPVs are completely withdrawn after polio eradication, but also may offer a

29 ne participant in VRC 319 and two in VRC 320 withdrew after one dose of vaccine, but were included in

30 acebo); one patient in the placebo group who withdrew after randomisation was not included in the ITT

31 s interesting properties due to the electron-withdrawing, albeit lipophilic, character of the SCF(3)

32 scenario, in which interconnected auxotrophs withdraw amino acids from the cytoplasm of donor cells,

33 en o-hydroxyacetophenones, carrying electron-withdrawing and -donating groups at positions 4 and 5, u

34 electronic influence of neighboring electron-withdrawing and -donating groups on the nucleophilic add

35 zaphosphorine 2-oxides that contain electron-withdrawing and -donating substituents on the 3-phenyl g

36 Our mechanistic study showed that electron-withdrawing and electron-donating core substituents affe

37 uccessfully with iodoarenes bearing electron-withdrawing and electron-donating groups, giving rise to

38 the aryl group, with both strongly electron-withdrawing and electron-donating substituents shown to

39 Various internal alkynes with electron-withdrawing and electron-donating substituents were tole

40 atic and heteroaromatic groups with electron-withdrawing and electron-donating substituents.

41 Both electron-withdrawing and electron-releasing substituents are well

42 ed into 2-aminofurans devoid of any electron-withdrawing and hence deactivating/stabilizing substitue

43 One participant was withdrawn and was replaced.

44 Five practices withdrew and 58 practices were randomly assigned: eight

45 d to avoid antiplatelet therapy, of whom one withdrew and was not analysed) and 254 (48%) underwent t

46 , 29% used PrEP prior to enrollment, 89 (3%) withdrew and were censored at date of withdrawal, leavin

47 with acetonitrile before an aliquot (I) was withdrawn, and the remainder was phase-separated using M

48 COPD, when inhaled corticosteroids should be withdrawn, and what other treatments are available.

49 as achieved in 396 patients (90%), 17 (3.9%) withdrew, and all others were followed up to 3 months.

50 bonds as the two electronegative CN ligands withdraw antibonding electron density from the bonding r

51 d the proton acceptors A (which are electron-withdrawing) are grouped together as in DDAA, there is a

52 rpyridines possessing electron-donating and -withdrawing aromatic residues for tuning the catalytic a

53 e diamine (dpen) as ligands bearing electron-withdrawing arylsulfonyl substituents, the reactions occ

54 enrolled patients, 4,433 were alive and not withdrawn at an LTFU participating center, and 3,833 (86

55 Withdrawing attention causes the alternating monocular d

56 anomeric charge development by the electron-withdrawing azide.

57 ll tolerated over 4 years; 4 (2.5%) patients withdrew because of adverse events that were considered

58 Forty-one patients (14%) withdrew because of adverse events.

59 to group randomization, and no participants withdrew because of an adverse event.

60 ed in the reservoir, and only a fraction was withdrawn before the end of the eruption.

61 Seven were withdrawn before treatment (n=1, n=1, n=5, respectively)

62 One patient withdrew before 6-month follow-up without having had a m

63 One subject in cohort B withdrew before receiving CYP-001 and was excluded from

64 6 patients (2 in 1500-mg, 4 in 3000-mg arm) withdrew before study completion.

65 that more reactive nucleophiles and electron-withdrawing benzoyl groups on the donor favor the format

66 ROAMP catalysts featuring electron-withdrawing benzylidynes not only selectively increase t

67 ere hemorrhagic shock was induced in rats by withdrawing blood until the mean arterial blood pressure

68 e Library (wileyonlinelibrary.com), has been withdrawn by agreement between the journal Editor-in-Chi

69 Ahead of Print article withdrawn by publisher.

70 he biomarker-guided recommendation group was withdrawn by the clinical team before bronchoscopy and s

71 the continued treatment group had treatment withdrawn by the same method.

72 zolonethione revealed the strongest electron-withdrawing character, resulting in the lowest band gap,

73 Electron-withdrawing chlorine substituents ensure response in the

74 destabilizing the (1)p* state by an electron-withdrawing CN substituent at the ortho or para position

75 s emulates in a controlled manner the proton-withdrawing conditions of polycrystalline films, where e

76 SVR12 did not complete treatment because of withdrawing consent after receiving 1 dose of study drug

77 , after removal of those who declined or had withdrawn consent, 2463 (95%) were included in the analy

78 extension study, four patients entered, one withdrew consent (week 24), three completed >=84 wk of t

79 21 (0.4%) patients immediately withdrew consent after randomisation and were excluded.

80 ding those who were considered ineligible or withdrew consent after randomisation) was used in primar

81 ccessful cannulation, but excluded those who withdrew consent after randomisation.

82 83 patients withdrew consent after the ERCP procedure, thus 1920 pat

83 r, one (<1%) patient in the ribaxamase group withdrew consent and was not treated with ribaxamase.

84 One patient (in the FST group) withdrew consent before drug administration and was excl

85 One (2%) patient from the HF-HD group withdrew consent before receiving treatment.

86 re available for analysis because 3 patients withdrew consent before scanning.

87 60 patients withdrew consent during the course of the trial (35 in t

88 55% male), 371 completed the trial; parents withdrew consent for 1 child treated with hydrocortisone

89 One participant allocated chemotherapy withdrew consent for data use after randomisation and wa

90 reat analysis that excluded the patients who withdrew consent for participation in the trial or who w

91 Ten participants withdrew consent or discontinued prematurely, 6 owing to

92 irradiation group and 14 from the APBI group withdrew consent or were lost to follow-up at this stage

93 e (<1%) woman in the concealed testing group withdrew consent to follow-up data collection, so 446 (>

94 Three participants in the placebo group withdrew consent without contributing a post-randomisati

95 d intention-to-treat basis (participants who withdrew consent without contributing a post-randomisati

96 d intention to treat (excluding patients who withdrew consent).

97 81 were included in the analysis (3 patients withdrew consent).

98 t metastases at the time of randomization; 2 withdrew consent).

99 , 51 (10%) couples did not consent to WES or withdrew consent, and five (1%) samples were not of good

100 ogression, began a new anticancer treatment, withdrew consent, died, had stable disease for 6 weeks o

101 One patient withdrew consent, leaving 3036 patients included in the

102 cumentation of informed consent, immediately withdrew consent, or randomly assigned to intervention g

103 After excluding 19 participants who withdrew consent, there were 384 patients (mean age, 60

104 inety participants were deemed ineligible or withdrew consent.

105 The strong electron-withdrawing cyano functionality enables DCNBT-IDT with n

106 ot attempt resuscitation and withholding and withdrawing decisions should be made according to standa

107 haalpha(+) IELs or long-term cognate antigen withdraw did not affect their maintenance.

108 Torcetrapib was withdrawn due to unanticipated off-target effects that i

109 ipants assigned to treatment minus those who withdrew due to a non-treatment-related cause.

110 Four subjects withdrew due to adverse events.

111 3.1%) patients, whereas two patients (15.4%) withdrew due to subjective side-effects at first dose.

112 One participant withdrew during the first closed-loop period because of

113 ng participants from 2 sites and who died or withdrew during the trial, 537 were included in this fol

114 rsudil and 96 to placebo; 15 eyes (16%) were withdrawn early from the netarsudil arm because of ocula

115 during the study; in addition, patients who withdrew early from the study were counted as having a f

116 easoned their stability through the electron-withdrawing effect of the carboxamide substituent.

117 The electron donating or withdrawing effect of the peripheral substituent ((t)Bu

118 1,5-triazole group exerts a strong electron-withdrawing effect on carbocations that is not offset by

119 l ((F) Mes) groups serve not only to further withdraw electron density but at the same time stericall

120 a variety of benzimidazoles having electron-withdrawing/electron-releasing/aliphatic groups under "m

121 The adsorbed As(V) ions withdrew electrons from Ce 4f orbitals and likely became

122 The key electron-withdrawing ester substituent on the Pd-oxyallyl species

123 The results show that the electron-withdrawing (EW) ability and density of these functional

124 a function of electron donating (EDG) and/or withdrawing (EWG) substituents.

125 were factors that influenced the decision to withdraw extracorporeal membrane oxygenation.

126 Estrogen-withdrawn females had increased anxiety-like behaviors i

127 Furthermore, estrogen-withdrawn females had more OT-immunoreactive cells and O

128 igh-anxiety behavioral phenotype in estrogen-withdrawn females.

129 g design, and a syringe pump was employed to withdraw fluid through the exit port of the NTA and main

130 rotocol allows the compatibility of electron-withdrawing fluoro, chloro, ester, and nitro and electro

131 n the placebo group (consent to use data was withdrawn for 1 woman and 2 infants).

132 No patients were withdrawn for adverse effects.

133 g patients who declined intervention or were withdrawn for protocol violations.

134 nger favored due to the presence of electron-withdrawing formyl moieties.

135 isions in patients with no time or option to withdraw from alcohol consumption is still a matter of d

136 ce is a mechanism by which cells permanently withdraw from the cell cycle in response to stresses inc

137 of patients, which also cause some drugs to withdraw from the market.

138 The adaptive significance of acute pain (to withdraw from tissue-damaging or potentially tissue-dama

139 ed their descendants, more recently, elderly withdraw from work and require assistance as well.

140 stence of response in subjects continuing or withdrawing from long-term omalizumab treatment.

141 on of patients experiencing 1 or more flares/withdrawing from the study was 50% lower with mepolizuma

142 ow that failure began after <4% of magma was withdrawn from a shallow reservoir beneath the volcano's

143 Error analysis show that animals withdrawn from both nicotine doses committed higher pers

144 to the hyperactivity of LHb neurons of rats withdrawn from chronic alcohol administration.

145 abenulo-interpeduncular circuit of male mice withdrawn from chronic nicotine treatment.

146 ethics committee and only five patients were withdrawn from drug treatment.

147 ate hormone levels during gestation and then withdrawn from estrogen to simulate postpartum estrogen

148 Some individual patients may, however, be withdrawn from methylphenidate without deterioration.

149 One subject was withdrawn from part 2 (80 mg cohort) before dosing and w

150 rational tolerance could be observed in LTRs withdrawn from SRL and if blood/graft tolerance biomarke

151 erational tolerance could be observed in LTR withdrawn from SRL and if blood/graft tolerance biomarke

152 nt may be helpful to select candidates to be withdrawn from surveillance programs.

153 The Absorb BVS device was withdrawn from the market because of low demand.

154 No patients were withdrawn from the study because of adverse effects.

155 evidence of disease progression on MRI, had withdrawn from the study to undergo allogeneic stem-cell

156 participants (<0.1% of the safety set) were withdrawn from the trial due to 21 adverse events by the

157 Nitarsone was withdrawn from the U.S. market in 2015, but its use in o

158 Responders were withdrawn from treatment (for up to 36 weeks) and re-tre

159 rmanently discontinued and patients were not withdrawn from trial but rather remained on follow-up fo

160 roup and 169 (5.5%) in the allopurinol group withdrew from all follow-up.

161 More participants who are BE-tolerant withdrew from BE versus from egg OIT (29.6% vs 13%).

162 ine were significantly lower in patients who withdrew from follow-up due to disease progression (n=6)

163 up for a median of 22 months (IQR 10-24; 53 withdrew from follow-up).

164 Two participants withdrew from the AQ-13 group after parasite clearance a

165 Eight (2%) withdrew from the study and were not included in analyse

166 Four patients withdrew from the study because of intolerance by 48 hou

167 in the ECMO-facilitated resuscitation group withdrew from the study before discharge.

168 Two (8%) participants withdrew from the study early: one participant in group

169 s: three were not properly randomised, three withdrew from the study, and one was lost to follow-up.

170 ny, did not meet all eligibility criteria or withdrew from the study.

171 One participant withdrew from the trial 240 days after enrolment and 12

172 ed ineligible after randomisation, those who withdrew from the trial and were unwilling for their pre

173 rate severity, 99% of cases); 4 participants withdrew from the trial for injection-related reasons.

174 two (6%) patients in the control group also withdrew from the trial.

175 or unavailability of the endoscopist while 8 withdrew from the trial.

176 roup did not receive allocated treatment and withdrew from the trial; two (6%) patients in the contro

177 millennium CE, and that the Byzantine Empire withdrew from this region due to a dramatic climatic dow

178 2.2%) discontinued natalizumab; 2117 (34.4%) withdrew from TOP.

179 enrolled into three groups; one participant withdrew (from group 1A).

180 Withdrawing glucose from exponentially growing cells rev

181 t, this structured MT network preferentially withdraws granules from the PM.

182 electron-donating group (EDG) or an electron-withdrawing group (EWG) and investigated the physicochem

183 ARF) of carbohydrates possessing an electron-withdrawing group (EWG) at C2, promoted by PhI(OAc)(2)/I

184 The influence of the electron-withdrawing group (EWG), present in the acyclic substrat

185 of an effect of the addition of an electron-withdrawing group are investigated.

186 rption and fluorescence, whereas an electron-withdrawing group at C-3 drives absorption and emission

187 hosphorus atom and the nature of an electron-withdrawing group have a significant impact on the spect

188 The effects of an electron-withdrawing group on the organic chemistry of an eta(2)-

189 this group: it primarily acts as an electron-withdrawing group that lowers the pK(a) of the neighbour

190 tonated aminomethyl functions as an electron-withdrawing group to reduce the barrier for thiolate add

191 ining an alkenyl moiety and diverse electron-withdrawing group(s) at the adjacent positions, into sub

192 he other one is substituted with an electron-withdrawing group.

193 -donating groups (e.g., methoxy) to electron-withdrawing groups (e.g., trifluoromethyl) were used to

194 Substrates carrying electron-withdrawing groups (EWGs) (0 < Esigma > 0.63) populated

195 Electron-withdrawing groups accelerate the reaction, providing a

196 styrenes with electron-donating and electron-withdrawing groups and works well on the gram scale.

197 etrical aniline derivatives bearing electron withdrawing groups are preferred compared to the symmetr

198 ence of either electron-donating or electron-withdrawing groups as substituents of the carbon pai-sys

199 tely opposite, with substrates with electron-withdrawing groups being favored.

200 In addition, the effect of electron withdrawing groups bonded to a nitrogen atom, namely the

201 or four new macrocycles bearing the electron-withdrawing groups CN, Cl, NO(2), and CF(3) are introduc

202 We indeed find that electron-withdrawing groups could enhance the stability of 2-PyH(

203 The use of sulfones as electron-withdrawing groups in substrates for palladium-catalyzed

204 e moiety, while the substitution of electron-withdrawing groups lowers the basicity.

205 ly electron-releasing or moderately electron-withdrawing groups on the aldehyde reactant.

206 rates bearing electron-donating and electron-withdrawing groups on the aromatic ring at both propargy

207 moted by N-oxyl radicals containing electron-withdrawing groups or when more polar solvents are emplo

208 Electron-withdrawing groups placed on the N-vinyl and N-aryl subs

209 tionalized by electron-donating and electron-withdrawing groups to afford a gradual increase of the e

210 to introduce electron-donating and electron-withdrawing groups to the phenolate ring.

211 and the observed effect of proximal electron-withdrawing groups upon the degradation rates.

212 Remarkably, aryls with electron-withdrawing groups, and electron-poor heteroarenes, such

213 like alkyls, ethers/thioethers, or electron-withdrawing groups, are discussed.

214 ble with a variety of electron-donating and -withdrawing groups, halogens, and nitrogen- and oxygen-c

215 Unlike BCBs bearing electron-withdrawing groups, which react with nucleophiles at the

216 group contains electron-donating or electron-withdrawing groups, with sulfated zirconium oxide partia

217 tron-deficient arenes with multiple electron-withdrawing groups.

218 egioselectivities were obtained for electron-withdrawing groups.

219 ly limited to substrates containing electron-withdrawing groups.

220 r smaller sp(2) carbons attached to electron-withdrawing groups.

221 c rings are modified with electron donating (withdrawing) groups, the reducing power is promoted (sup

222 Among 401 randomized patients, 2 withdrew immediately after randomization, and 1 duplicat

223 Three patients per group withdrew immediately after randomization.

224 s of clinical trials designed to minimize or withdraw immunosuppressive drugs in kidney, liver, and l

225 salt, that is, electron-donating or electron-withdrawing in the ortho, meta, or para positions.

226 , care was adapted in up to 71%, withheld or withdrawn in 58%, and resuscitation was withheld in ever

227 ough studies indicate that Tac can be safely withdrawn in a subset of kidney transplant recipients, i

228 Finally, each respective phase is withdrawn into its respective pump.

229 nary fibrosis, stroke, surrogate's desire to withdraw, lack of knowledge regarding patient's or surro

230 Similarly, withdrawing lactose from the diet does not reduce intest

231 e primary solution to lactose intolerance is withdrawing lactose from the diet either by eliminating

232 tion of substituents as electron donating or withdrawing leads to a perceived dominance of through-bo

233 Seven women withdrew, leaving 1715 in the amoxicillin and clavulanic

234 r follow-up 14 were lost to follow-up and 12 withdrew, leaving 3031 to enter 10-year follow-up analys

235 One participant withdrew, leaving a sample size of 21.

236 ed suicide and euthanasia and withholding or withdrawing life support, 3) the morality of a physician

237 s, factors associated with increased odds of withdrawing life-sustaining therapies included pulmonary

238 ardiopulmonary resuscitation and withholding/withdrawing life-sustaining treatments, using a three-le

239 Results were similar for withholding/withdrawing life-sustaining treatments.

240 uid" and still responsive state of the early withdrawn maladaptive synapses may help in the treatment

241 a potential side effect of many marketed and withdrawn medications.

242 42% of American studies, and was withheld or withdrawn more frequently over time with a median of 58%

243 their alkyl analogues owing to the electron-withdrawing nature of the attached subunit.

244 Although the electron-withdrawing nature of the CF(3) group should facilitate

245 The electron-withdrawing nature of the dinitrobenzene moieties can tr

246 This is rationalized based on the electron-withdrawing nature of the radical site(s).

247 in NH stretching frequency and the electron withdrawing nature of the substituent, consistent with t

248 multifunctional framework of strong electron-withdrawing nature.

249 This article was withdrawn on October 15, 2020, at the request of the jou

250 s that had used OPV in 2015 had successfully withdrawn OPV2 by ceasing use of tOPV in their national

251 6 individuals who initiated PrEP and did not withdraw or die before the first visit, 2215 (64%) were

252 presentations of clinical trials designed to withdraw or minimize immunosuppressive (IS) drugs in kid

253 on to an intensive care unit, or decision to withdraw or withhold life-sustaining treatments, whichev

254 nd as determined by the presence of electron-withdrawing or -donating substituents at C(2).

255 m(-1) (1) to -11.1 cm(-1) (4), with electron-withdrawing or -donating substituents increasing or decr

256 Furthermore, the presence of electron-withdrawing or -donating substituents substantially impa

257 radicals' self-decay with different electron-withdrawing or -donor substituents in the benzene ring a

258 78 participants were withdrawn or lost to follow-up during the study; thus, t

259 icrobiome even after the private resource is withdrawn or made public.

260 y were allocated, excluding participants who withdrew or died before providing any outcome data).

261 tion, and 13 (2%) were excluded because they withdrew or died before providing any outcome data.

262 Six patients withdrew or had protocol violations.

263 Highly electron-withdrawing pentafluorosulfanyl groups were probed as su

264 ole product, is destabilized by the electron-withdrawing phthalimide substituent.

265 ising bacterial macrolide resistance but was withdrawn postapproval after visual disturbances, syncop

266 18, 24 TGM and 24 TGW were enrolled; one TGM withdrew prior to 4 weeks of PrEP.

267 IL-19 increased upon ixekizumab withdraw, prior to relapse, and decreased following re-t

268 s spanning a range of electron-donating and -withdrawing propensities.

269 l groups of differing electron-donating and -withdrawing properties.

270 n at the P centers, the presence of electron-withdrawing R groups, and metal coordination to the soft

271 d anxiety-like behavior was also observed in withdrawn rats at this same time point.

272 ltered NMDAR/AMPAR ratio observed in alcohol-withdrawn rats.

273 charged amine or with electron-donating or -withdrawing ring substituents displayed decreases in cat

274 elds and side groups with different electron-withdrawing strengths that fine-tune their redox propert

275 etrical aryl-aryl alkenes having an electron-withdrawing substituent at one of the aryl groups.

276 t of either an electron-donating or electron-withdrawing substituent is to increase the stability of

277 exation for arenes bearing strongly electron-withdrawing substituents (sigma > 0.43).

278 es as an example case, these highly electron-withdrawing substituents allow for polymerization of eth

279 with positive slope indicating that electron-withdrawing substituents enhance the radical-cation acid

280 tuents leading to a weaker bond and electron-withdrawing substituents leading to stronger bonds, foll

281 The presence of two electron-withdrawing substituents on both sides of the nitronyl f

282 titution and is thus accelerated by electron-withdrawing substituents on the aromatic ring.

283 H3)(CF3)2)3] featuring electron-donating or -withdrawing substituents on the benzylidyne.

284 yl amide ion pairs carrying various electron-withdrawing substituents were synthesized with selected

285 Bronsted acid organocatalysts with electron-withdrawing substituents were synthesized, and their rel

286 activation of the aromatic ring by electron-withdrawing substituents, such activating groups are not

287 or a series of aryl sulfonates with electron-withdrawing substituents, the rate of deprotection for t

288 e accessible by combining bulky and electron-withdrawing substituents.

289 d a series of electron-donating and electron-withdrawing substituents.

290 formance by consecutively administrating and withdrawing testosterone.

291 ted very predominantly the strongly electron-withdrawing tg conformation of their side chains, which

292 hotoreceptors within two hours of induction, withdrew their dendrites between twelve hours and one da

293 The authors have requested to withdraw this manuscript from publication because the st

294 ive did not complete the trial (two patients withdrew [travel burden, severe pre-existing comorbidity

295 The safety of withdrawing treatment in this situation is unknown.

296 The main reasons described for withdrawing trust were: inability to follow instructions

297 sing between 05.30 hours and 21.00 hours was withdrawn, UK children (n = 13,729,000), would see on av

298 displaced to after 21.00 hours, rather than withdrawn, we estimate that the benefits would be reduce

299 ancreas was low in both groups until CNI was withdrawn, with four of the five pancreas rejections occ

300 reversal, or bleeding prophylactic agents or withdrawn within the study time frame.