1 approach to manipulate acetylation on H2A.Z
without impacting acetylation of other histone types.
2 rapy (SBRT) allows shorter treatment courses
without impacting acute toxicity.
3 by promoting local inflammatory events, but
without impacting adaptive immunity in this experimental
4 ctivity by increasing the rate of hydrolysis
without impacting affinity for ATP substantially.
5 e in glutamate and reduced insulin secretion
without impacting alanine levels.
6 agen IV scaffold in a dose-dependent manner,
without impacting already established scaffolds.
7 significantly reduced spontaneous scratching
without impacting anxiety-like behaviors.
8 m-permeable AMPARs (with NASPM) reduced CLAD
without impacting AOD.
9 the objective of enhancing these properties
without impacting apoptosis-inducing activity.
10 ts (112 +/- 10 to 109 +/- 9 mmHg, P = 0.049)
without impacting arterial stiffness, FMD, GMD, or NO.
11 d behavioral sensitivity to deviant stimuli,
without impacting baseline performance.
12 ions, A3, decreases auto-inhibitory function
without impacting binding to importin beta or the import
13 n-36 that could modulate glucose homeostasis
without impacting blood pressure (or activating APJ).
14 hanced pathogenic neovascular tuft formation
without impacting blood vessel repair.
15 epithelial (HBE) cells from patients with CF
without impacting calcium signaling.
16 (TNF-alpha) that selectively activates Tregs
without impacting CD4(+)FoxP3(-) T cells.
17 ers resistance to CSF1R inhibitors (CSF1Ris)
without impacting cell or organismal function, allowing
18 mal genes and promoted an invasive phenotype
without impacting cell proliferation.
19 ion by >2,000-fold in multiple viral strains
without impacting cell viability.
20 000 pM, regardless of reporter construct and
without impacting cellular viability.
21 lung parenchyma, decreasing lung compliance
without impacting central venous pressure.
22 atment that selectively degrades linear RNAs
without impacting circular RNAs.
23 ansition and reducing the number of features
without impacting classification performance.
24 tudy approaches to support information needs
without impacting clinical workflow.
25 ver targeting GalNAc-conjugated anti-siRNAs,
without impacting CNS activity.
26 e-induced locomotion and self-administration
without impacting cocaine-induced behaviours.
27 further reduce the complexity of these data
without impacting downstream analyses.
28 immune response and are safe for human use,
without impacting efficacy.
29 with fewer attacks suggests lower resilience
without impacting efficiency.
30 nd larger lipid droplets in brown adipocytes
without impacting either mitochondrial morphology or exp
31 the incidence of day +100 severe acute GVHD
without impacting engraftment or survival.
32 c hematopoietic stem cell transplant (HSCT),
without impacting engraftment.
33 fied that increased on-target residence time
without impacting equilibrium binding affinity.
34 Utilizing bougie >/=40 Fr may decrease leak
without impacting %
EWL up to 3 years.
35 which in turn sculpt inhibitory connectivity
without impacting excitatory synapses.
36 ticoagulant that suppresses fibrin formation
without impacting fibrinogen levels.
37 133) were unable to infect endothelial cells
without impacting fibroblast infection.
38 infection by recent H3N2 virus strains, but
without impacting final virus titers.
39 easily mutate their immunodominant epitopes
without impacting fitness.
40 Neither biofuel can replace much petroleum
without impacting food supplies.
41 cence exit and confers competitive advantage
without impacting function.
42 such that fibrin polymerization is impaired
without impacting FXIII-mediated cross-linking.
43 error, including spillover and sample swaps,
without impacting genome recovery.
44 etic determinants that can control phenotype
without impacting genotype.
45 rct area and reduces cell death in the core,
without impacting gliosis.
46 lective targeting of GPCRs in intended pests
without impacting GPCR activity in non-targeted organism
47 ) and enhanced the protective statin effect,
without impacting graft-versus-leukemia (GVL) activity.
48 HCF244 activates downstream of those events
without impacting HCF173's binding to psbA mRNA.
49 eases by achieving potent, durable remission
without impacting healthy immune surveillance.
50 is in DBA models and diverse patient samples
without impacting hematopoietic stem cell function or de
51 expression conferred a competitive advantage
without impacting HSPC numbers.
52 r by which diprovocims can be functionalized
without impacting hTLR1/TLR2 activity is detailed, permi
53 ed proximal IL-23 signaling (IC(50): 5.6 pM)
without impacting IL-12 signaling.
54 RK in response to T cell receptor engagement
without impacting IL-2/Stat5 signaling.
55 presses chromosome shattering during mitosis
without impacting interphase-associated defects within m
56 run on gram-scale with low catalyst loading
without impacting its efficiency.
57 on a gram scale with a low catalyst loading
without impacting its efficiency.
58 on a gram-scale with a low catalyst loading
without impacting its efficiency.
59 lity at the immunoglobulin heavy-chain locus
without impacting its transcriptional activity, AID recr
60 atin loops and lowered nascent transcription
without impacting LDB1's chromatin binding.
61 hality, and reduced lacrimal gland branching
without impacting lens development, suggesting that Shp2
62 ific positive allosteric modulator VU0360172
without impacting locomotion-relevant behavior.
63 e than 90% in clinically relevant cell types
without impacting long-term viability or expansion.
64 dominantly through noncompetitive inhibition
without impacting membrane expression.
65 back-projections enhanced motion sensitivity
without impacting metacognition, whereas boosting IPS/LI
66 nce of MF credit assignment by MB inference,
without impacting MF and MB influences directly.
67 rying to improve efficiency and productivity
without impacting milk nutritional properties.
68 ojections increased metacognitive efficiency
without impacting motion sensitivity.
69 reduced MUC5B expression after RV infection
without impacting MUC5AC.
70 rgets the affinity for aggregated structures
without impacting native folding, and hence impairs its
71 e to remove efficiently the volatile phenols
without impacting negatively on the wine sensory quality
72 nd induces differentiation of leukemic cells
without impacting normal hematopoietic cells.
73 iferation, tumourigenesis and RAC1 activity,
without impacting normal homeostasis.
74 s protects against Abeta-induced impairments
without impacting normal physiological Abeta functions.
75 significantly enhance the energy efficiency
without impacting on economic costs.
76 otent peptide antagonist of aS pathogenicity
without impacting on native aS function.
77 of crop varieties with effective resistance
without impacting on other agronomically important crop
78 binding energy do so by increasing off rates
without impacting on rates.
79 The pharmacological tuning of Treg activity
without impacting on T conventional (Tconv) cell activit
80 portions of 16:1n-7 and 18:1n-7 in the liver
without impacting on the level of 18:1n-9, suggesting th
81 benefits of decompression and cytoreduction,
without impacting on the patient's neurological status.
82 s efficient in increasing tartaric stability
without impacting on the phenolic composition, sensory c
83 Reactions may also be performed in air
without impacting on the rate or selectivity of epoxide
84 oted the Treg and inhibited the Th17 program
without impacting on viability, proliferation and activa
85 channel open probability (P(o)) that occurs
without impacting on voltage sensor movement, and (3) an
86 uenced LR of well differentiated liposarcoma
without impacting OS, whereas discrepancies in adjuvant
87 use of apoptosis within 48 hours of exposure
without impacting osteoclast precursor cells.
88 ic LPV/RTV-IFNb slightly reduces viral loads
without impacting other disease parameters.
89 reased the level of endogenous FoxO1 protein
without impacting other factors such as C/EBPalpha and C
90 targeting of a unique, specific G4 structure
without impacting other off-target G4 formations.
91 ucts that disrupt specific receptor features
without impacting others.
92 ns depressed compound AN responses by 40-70%
without impacting otoacoustic emissions or behavioral to
93 layer allows more protection for the explant
without impacting outcomes.
94 rosis by limiting p53 transcriptional output
without impacting p53 chromatin binding.
95 controlling antibiotic use, decreasing costs
without impacting patient outcomes, and possibly decreas
96 entrusted to appropriately skilled trainees
without impacting patient outcomes.
97 activation of ATF6 mitigates 1-dSL toxicity
without impacting PERK/ISR signaling.
98 t development under low phosphate conditions
without impacting phosphate homeostasis.
99 In poplar, mannan content was altered
without impacting plant growth.
100 lifespan in female but not male GA-Nes mice,
without impacting poly-GA aggregates.
101 rther enabled deletion of up to six residues
without impacting potency, thus improving peptide ligand
102 n (replacement of OMe) or 3- and 4-positions
without impacting potency.
103 of MHC-Ia-restricted CD8(+) T cell epitopes
without impacting presentation of peptide antigen bound
104 signaling selectively attenuates metastasis
without impacting primary tumor growth.
105 equired for EGFR-mediated metastasis in vivo
without impacting primary tumor growth.
106 density fermentations, abolished sporulation
without impacting product formation, and genetic stabili
107 the potential to decrease lung tissue damage
without impacting protective immunity against TB.
108 onstruct that disrupts TA-dependent activity
without impacting proteolysis, we explored other mutatio
109 wed GluK2a kainate receptor current kinetics
without impacting receptor membrane localization.
110 an be beneficial in attenuating chronic pain
without impacting responses to the protective physiologi
111 essibility by increasing the unwrapping rate
without impacting rewrapping.
112 ion of RGS7 shRNA directly to the myocardium
without impacting RGS7 levels in the liver directly.
113 sts also strongly reduced both CLAD and AOD,
without impacting saccharin intake or locomotion, while
114 he variability and normalized cuff pressures
without impacting sealing performance.
115 relative to capillary zone electrophoresis,
without impacting separation resolution or analysis time
116 cellular inflammatory responses after injury
without impacting sham controls.
117 ternalized by human bone marrow-derived MSC,
without impacting significantly their proliferation or i
118 and c-Jun N-terminal kinase (JNK) activation
without impacting Smad2 activation or TGF-beta-induced g
119 native drugs that target bacterial virulence
without impacting survival directly offer an attractive
120 uces fibrosis and restores autonomic balance
without impacting systemic insulin resistance or hyperin
121 ibition increases autophagic Tau degradation
without impacting Tau production.
122 omeres, profoundly impairing ALT cell growth
without impacting telomerase-positive cells.
123 (Th) 1/17 differentiation and Treg formation
without impacting Th2 differentiation.
124 can modulate the frontier molecular orbital
without impacting the bandgap.
125 ion of genes involved in glucose metabolism,
without impacting the basal oxygen consumption rate.
126 lso be conjugated to biofunctional molecules
without impacting the complexed dyes.
127 n a gram scale with reduced catalyst loading
without impacting the efficiency.
128 he upregulation of phosphorylated Akt (pAkt)
without impacting the ER level or activity.
129 lay slightly the time course of the outbreak
without impacting the eventual number ill.
130 ion and infectious virus production by EG PV
without impacting the final yield of replicated RNA or i
131 sitive MVBs/LEs with lysobiphosphatidic acid
without impacting the fraction of EEA1-positive CD63.
132 enting virus-induced tissue damage and death
without impacting the generation of inflammatory antivir
133 ables high-velocity (100-400 mm/s) operation
without impacting the integrity of the cell membrane.
134 on that correlate with this enhanced potency
without impacting the intrinsic selectivity characterist
135 een pathways that yield nitrite and nitrate,
without impacting the level of S-nitrosylation or extent
136 elective inhibition of the canonical pathway
without impacting the many non-canonical NF-kappaB funct
137 erapeutic targets for curbing opioid craving
without impacting the natural reward system in males and
138 gulates CRAC channel-evoked c-fos activation
without impacting the NFAT pathway or Orai1 activity.
139 n complete inactivation of the mutant allele
without impacting the normal allele.
140 njury, stroke and multiple sclerosis models,
without impacting the peripheral immune system.
141 we reduced the marker set from 217,563 to 50
without impacting the predictive ability.
142 oaches to include such features in the model
without impacting the predictive accuracy.
143 c cytokine-producing effector B cell subsets
without impacting the protective regulatory subsets.
144 the renal RE responses to hyperglycemia but
without impacting the RAAS or NO levels, suggesting that
145 ncreases in RE, PGLO, and interleukin-18 but
without impacting the RAAS.
146 al data that should be collected in parallel
without impacting the rapid path to clinical development
147 significantly increases the mean TPF signal (
without impacting the SHG signal) and the storage modulu
148 was effective for at least four filtrations
without impacting the subsequent microbial removals, whi
149 and increased recruitment of motor neurons,
without impacting the timing of spiking across or along
150 nt driving pressure affect the clogging rate
without impacting the underlying dynamics.
151 cancer cell lines, including NSCLC and AML,
without impacting the viability of nontransformed cells.
152 of initiator caspases or upstream regulators
without impacting their proteolytic activity.
153 nificantly impaired lung metastases in vivo,
without impacting their recruitment to the lungs or alte
154 tation in conventional dendritic cells (DCs)
without impacting their survival.
155 ia and co-ordinates NPC spatial organization
without impacting total NPC density.
156 intermediate- and high-risk prostate cancer
without impacting toxicity and quality of life.
157 salivary glands from irradiation (IR) damage
without impacting tumor therapy.
158 of blocking autoreactive CD8 T-cell function
without impacting upon general immune competence.
159 rvival, and production of juvenile steelhead
without impacting upstream and downstream migrations.
160 CD47 inhibited Vav phosphorylation
without impacting Vav recruitment to the phagocytic syna
161 een observed in animal models of depression,
without impacting vHipp activity and PV/PNN expression.
162 Ceapins sensitize cells to ER stress
without impacting viability of unstressed cells.
163 proliferation of live bacteria over 28 days,
without impacting viability of vaginal epithelial cells.
164 city to a level that is acceptable worldwide
without impacting viral production in cell culture.
165 ntities may sustainably reduce GHG emissions
without impacting yields.