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1 recipitation sequencing of a patient-derived xenograft.
2 accomplished using a bovine versus a porcine xenograft.
3 ng PSMA(+) PC3 PIP and PSMA(-) PC3 flu flank xenografts.
4 egative patient-derived cell lines and mouse xenografts.
5 ith high uptake in lymphoid tissue and hPBMC xenografts.
6 CC cell xenografts and patient-derived tumor xenografts.
7 nation was ineffective against neuroblastoma xenografts.
8 1 antagonist treatment of melanoma and NSCLC xenografts.
9 xenografts compared to wild-type ATM control xenografts.
10 R, suppressing the growth of Ewing's sarcoma xenografts.
11 th as either subcutaneous or intraperitoneal xenografts.
12 ndent MYC expression and AML growth in mouse xenografts.
13 lastoma cell lines, primary human cells, and xenografts.
14 The tracer accumulates in CHL-GLP-1R xenografts.
15 (CRC) growth in cell culture and mouse tumor xenografts.
16 onse to anti-Cdk5 therapy in patient-derived xenografts.
17 remissions in 80% to 100% of NB and sarcoma xenografts.
18 cancer progression in GC cells and in mouse xenografts.
19 /c nude mice bearing subcutaneous CHL-GLP-1R xenografts.
20 thymic nude mice bearing subcutaneous MKN-45 xenografts.
21 sed cell growth both in culture and in mouse xenografts.
22 icroscopy of orthotopic sarcoma and melanoma xenografts.
23 line models and suppressing growth in tumor xenografts.
24 c bystander effects in delayed growth of DTC xenografts.
25 and angiogenesis in the human bladder cancer xenografts.
26 ivated the lytic cycle, including in Burkitt xenografts.
27 ty to T cell attack in vitro and in melanoma xenografts.
28 regional blood flow in the FME and LOX tumor xenografts.
33 t HCC cell lines in vitro, and HCC tumors in xenograft and patient-derived xenograft mouse models.
39 single-cell characterization of human tumor xenografts and in vivo CRISPR screens identified essenti
40 ns, we used the octapeptide to detect tumour xenografts and metastatic lesions, and to perform fluore
41 y arrested the growth of neratinib-resistant xenografts and organoids established from neratinib-resi
42 This study examined prostate cancer (PCa) xenografts and patient samples to identify in vivo mecha
44 hibitor pazopanib in MKN45 gastric carcinoma xenografts and the combination of tubulin-targeting agen
45 of firefly luciferase-expressing Hep3B tumor xenografts and the effects of the immune response during
46 S to four cell lines, to a cell-line-derived xenograft, and to normal and paired tumor/normal primary
47 rowth of breast cancer cells in vitro and in xenografts, and may be a novel approach for the safe and
48 +/- 23.7 %ID/g, respectively) in LNCaP tumor xenografts, and this peak was sustained up to 120 h afte
54 o the periphery; following clearance of ATRT xenografts, B7-H3.BB.z-CAR T cells administered intracer
60 aneous or intraperitoneal human OVCAR-3 OvCa xenografts by dynamic PET/MRI, ex vivo biodistribution,
61 his system enabled intravital observation of xenografts by multiphoton microscopy, allowing us to vis
62 ibitor nilotinib in MDA-MB-468 breast cancer xenografts) caused changes in the tumor epithelial-mesen
63 de for using immunocompromised zebrafish for xenograft cell transplantation and credentials the model
66 promotes growth of ATM CRISPR knockout DLBCL xenografts compared to wild-type ATM control xenografts.
67 s strong inhibition of tumor growth in mouse xenografts, compared with MEK5 depletion or radiation al
69 tient-derived monosomal karyotype AML murine xenografts, decitabine treatment resulted in superior su
70 to induce an 80% tumor growth inhibition of xenografts derived from the enzalutamide-resistant (Enz-
71 on a panel of three patient-derived lymphoma xenografts derived from two patients with R/R B-NHL and
73 Bevacizumab-resistant patient specimens and xenografts exhibited decreased vessel density and increa
76 osis in vitro Likewise, in in vivo human GBM xenograft experiments with immunodeficient mice, mAb tre
77 ts of cancer mutations on tumor formation in xenograft experiments, and functional annotation based o
80 ase inhibitor CB-839 preferentially inhibits xenograft growth of PIK3CA-mutant, but not wild-type (WT
81 icroglial chimeric mouse brains reveals that xenografted hPSC-derived microglia largely retain human
82 significantly regressed tumor growth in the xenograft human hepatocellular carcinoma mouse model.
87 culture, and dramatically inhibited in vivo xenografts in mice, but had no effect on normal control
91 ation, Y537S-ER, were used to generate tumor xenografts in ovariectomized female immunodeficient mice
98 nt of nude mice bearing FR-positive KB human xenografts led to cures in 100% of the test animals with
99 ds glioblastoma (GBM) and prostate carcinoma xenograft lesions in nude mice (eight and five-fold resp
100 tudies demonstrated that, when ectopic human xenograft LNCaP tumours in SCID mice were treated with S
101 breast cancer cells implanted as orthotopic xenografts, loss of G6PD modestly decreased primary site
107 d experimental lung metastasis in the HT1080 xenograft model and highlight the critical role of fibri
110 r, BKM120, was tested in our patient-derived xenograft model leading to disease attenuation and prolo
112 graft mode of melanoma and a patient-derived xenograft model of colon cancer with a favorable safety
116 extended animal survival in patient-derived xenograft model systems in vivo more potently than singl
117 of 5-FU was shown in a colorectal zebrafish xenograft model that led to significant reductions in tu
119 nation (Olaparib + BKM120) in the MDA-MB-468 xenograft model with a tumor growth inhibitory rate of 7
121 (ABC) diffuse large B-cell lymphoma (DLBCL) xenograft model, but this compound suffered from a short
123 elevant renal cell carcinoma patient-derived xenograft model, we use the (89)Zr-labeled anti-RTK anti
135 t that, unexpectedly, in two different mouse xenograft models and four human and mouse cell lines we
136 s costimulated with 4-1BB or ICOS persist in xenograft models but those constructed with CD28 exhibit
137 and reduction of tumor burden in three mouse xenograft models driven by either wild-type or mutant RA
141 combination against multiple patient-derived xenograft models makes it an excellent candidate for fur
147 r functional studies in multiple culture and xenograft models reveal a coordinated role of GATA3 and
148 ibited strong monotherapy efficacy in cancer xenograft models that carry certain DNA damage repair de
149 ome program conserved across patient-derived-xenograft models that is highly predictive of poor survi
150 bioavailability in ovarian and colon cancer xenograft models when evaluated for dose-ranging efficac
153 ful establishment of estrogen-sensitive HGSC xenograft models, OVSAHO and COV362, this work will enab
154 -mutated leukemia, including patient-derived xenograft models, through downregulation of key genes in
155 addition, using different CD127+ T-ALL/T-LBL xenograft models, we also reveal that residual tumor cel
156 ss diverse AML cell-line and patient-derived xenograft models, we find that acquisition of resistance
171 clinical verification of in vitro data using xenograft mouse model of MSCs confirmed the clinical rel
172 RNA using nanoparticles to the neuroblastoma xenograft mouse model showed around 15-20% ITCH silencin
173 ime that p190A is a tumor suppressor using a xenograft mouse model with carcinoma cells harboring def
174 isplays robust transduction in a human liver xenograft mouse model with expanded tropism for both mur
178 from cell line models, clinical samples and xenograft mouse models revealed mitogen-activated protei
179 Functional assessment in patient-derived xenograft mouse models validated the notion that MYC, YA
181 , a miR-497 target, suppress tumor growth in xenograft mouse models, proposing the TAp63-miR-30c-2*/m
188 olonged survival from 27 to 70 days in a GBM xenograft mouse resection model with no sign of tumour r
189 rosomal stability effectively suppressed the xenograft of MIA PaCa-2, a K-Ras(G12C)-expressing human
190 in transgenic TH-MYCN mice; (ii) orthotopic xenografts of a drug-resistant NB line SK-N-BE(2)C (muta
191 line SK-N-BE(2)C (mutated TP53); (iii) flank xenografts of a drug-resistant NB-PDX; and (iv) xenograf
192 d by oral administration of 27 in orthotopic xenografts of endocrine-resistant breast cancer in monot
194 using an in vivo mouse model with orthotopic xenografts of HCC cells confirmed the in vitro data, and
195 d reduced growth of HCC cells in culture and xenografts of HCC tumors, suggesting that inhibition of
198 hantoms and followed by in vivo treatment of xenograft pancreatic cancer (BxPC-3) tumours in a murine
200 ablished a unique patient-derived orthotopic xenograft (PDOX) nude mouse model of a highly aggressive
201 report the establishment of patient derived xenograft (PDX) and cell line models that reflect the ge
202 ore, when using intracranial patient-derived xenograft (PDX) approaches, it is advantageous to deploy
204 Using molecularly classified patient-derived xenograft (PDX) lines, cultured in stem-cell conditions,
205 4 genomic signatures using a patient-derived xenograft (PDX) model treated with an FGFR4 inhibitor, w
206 e myelogenous leukemia (AML) patient-derived xenograft (PDX) models of acquired resistance to BCL-2 (
208 mAbs) to CD3 have antileukemic properties in xenograft (PDX) models of CD3+ T-ALL, resulting in prolo
209 valuated against FR-positive patient derived xenograft (PDX) models of ovarian (ST070), endometrial (
214 his study aimed to develop a patient-derived xenograft (PDX) tumor in mice by using a tumor from a pa
216 drogenase (ALDH) activity of patient-derived xenograft (PDX) tumors, which was reversed by combinatio
217 BRAF(V600E)-driven melanoma patient-derived xenografts (PDX) and diminishes growth of NRAS(Q61R)-dri
218 Ex vivo models such as mouse patient-derived xenografts (PDX) and organoids are being developed to pr
219 embled a panel of orthotopic patient-derived xenografts (PDX) and subjected them to DNA sequencing, g
221 lone inhibited the growth of patient-derived xenografts (PDX), and SVC112 combined with radiation res
222 A panel of patient-derived ovarian cancer xenografts (PDX), similar in genetics and chemotherapy r
225 ensitive and resistant patient-derived tumor xenografts (PDXs) indicate that PGM3 expression is speci
227 in HER2-mutant breast cancer patient-derived xenografts (PDXs) was also associated with TORC1 hyperac
230 thotopic transplantation and patient-derived xenograft preclinical models, we defined clear functions
231 of the PARP inhibitor talazoparib in murine xenografts provides tumor suppression equivalent to a mo
232 istent survival of life-supporting pig heart xenograft recipients beyond 90 days was recently reporte
233 isotope tracing analysis in patient-derived xenografts revealed differences in nutrient handling bet
235 tics in mice bearing receptor-positive tumor xenografts revealed up to 4-fold increased tumor uptake
236 clinical breast tumours and patient-derived xenograft samples that are resistant to endocrine therap
237 -231 breast cancer and FaDu head neck cancer xenografts show different pO(2) responses during each of
238 ever, small-animal PET studies in HT1080hFAP xenografts showed higher specific tumor uptake of [(18)F
242 lso highly metastatic to lung and liver when xenografted subcutaneously in immune-deficient NSG mice.
243 estingly, NRP-1-depleted patient-derived GBM xenografts substantially prolonged survival in mice comp
244 lax in FP-RMS cell lines and patient-derived xenografts synergistically induced cell death and signif
249 tal microscopy of colorectal cancer organoid xenografts to investigate the cell of origin of metastas
250 , and when given orally effectively inhibits xenograft tumor growth and induces survivin loss in tumo
251 Furthermore, knockdown of PTPRF inhibited xenograft tumor growth in vivo and decreased the express
253 54, and GEM results in a potent reduction of xenograft tumor growth without any obvious side effects
254 verall, these data show that Rh-PPO inhibits xenograft tumor growth, supporting the strategy of using
262 Amiodarone markedly reduced the size of GBM xenograft tumors and displayed a strong anti-angiogenic
264 tradiol, but only UM-SCC-12, not UM-SCC-11A, xenograft tumors grow larger in vivo in response to syst
267 pancreatic cancer cells, increased growth of xenograft tumors in mice, and increased expression of th
272 compounds, penfluridol, slowed the growth of xenograft tumors in the different mouse models, reducing
275 there was a change in (64)Cu-ATSM signal in xenograft tumors smaller than 50 mg but not in larger tu
276 nin sensitizes triple-negative breast cancer xenograft tumors to chemotherapeutics and reduces metast
278 rall survival by controlling patient-derived xenograft tumors with greatly reduced host toxicities.
279 duction between different regions of CA20948 xenograft tumors, suggesting that different parts of the
286 tablished orthotopic GBM neurosphere-derived xenografts using advanced nanoparticle formulations redu
287 with a combination of osseous allograft and xenograft was used in 73 cases, 53 of which had preopera
288 nscript analysis of matching patient-derived xenografts we constructed dedicated classifiers for expe
289 otodynamic therapy in mice with subcutaneous xenografts, we observed a substantial and immediate occl
290 ype (WT) and ESR1-silenced LSCC cultures and xenografts were examined for 17beta-estradiol responsive
294 CA20948 somatostatin receptor-positive tumor xenografts were treated with (177)Lu-DOTATATE or sham-tr
295 f gold nanoparticles within MCF7 tumor mouse xenografts which is followed by its photothermal remedia
296 both cultured cells and lung adenocarcinoma xenografts, while a subset had clinically relevant tumor
297 astasis, and reduces the survival of animals xenografted with Pten-NOLC1-expressing cancer cells.
298 human pancreatic ductal adenocarcinoma tumor xenografts with differing physiologic and metabolic char
299 an glioblastoma and describe patient-derived xenografts with species-conserved subtype-discriminating