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1 ese crowberry) is rich in calcium, iron, and zinc.
2 These particles did not contain oxidized zinc.
3 mized during 2013-2017 (1,185 folic acid and zinc, 1,185 placebo); they had a mean age of 33 years an
4 (cobalt, copper, manganese, molybdenum, and zinc), 4 metals with some evidence of normal physiologic
6 isorder in ZIF glasses using ultrahigh-field zinc-67 solid-state nuclear magnetic resonance spectrosc
7 diting activity was sensitive to addition of zinc acetate or the zinc chelators 1,10-o-phenanthroline
9 one rescues not only mutations that decrease zinc affinity, but also mutations that destabilize DBD w
14 reover, we observed reduced plasma levels of zinc-alpha-2-glycoprotein, butyrylcholinesterase, and in
17 ll, these results indicate new functions for zinc and copper in the modulation of the cytoskeleton mo
18 tify essential trace elements (iron, copper, zinc and iodine) and establish their speciation in human
19 bread wheat genotypes characterized for the zinc and iron content, the most important micronutrients
21 ch regulates concentrations of intracellular zinc and is increased in pancreatic cancer cells, in cel
25 veal the co-localization at the nanoscale of zinc and tubulin in dendrites with a molecular ratio of
27 izes the known molecular mechanisms of iron, zinc, and B vitamin processing by human-associated bacte
29 the concentrations of vitamin C, vitamin E, zinc, and copper in both national and regional brands of
30 measured quantities of vitamin C, vitamin E, zinc, and copper were slightly higher than labeled but n
31 measures of serum ferritin (SF), vitamin A, zinc, and CRP measured using different assays with varia
34 pendent on the lot, correlating with initial zinc availability (i.e., less MIC reduction with higher
35 le fertility commonly contain folic acid and zinc based on limited prior evidence for improving semen
36 ect, inhibitors bearing two pharmacophores-a zinc binding group and a Cys-reactive warhead-were desig
38 tiple ribosomal (r-) proteins containing the zinc-binding CXXC motif are replaced by their motif-free
39 d a distinct architecture in which the beta' zinc-binding domain (ZBD) of RNAP stretches out from its
40 V, which has multiple domains: an N-terminal zinc-binding domain (ZBD), a 1B domain, and helicase cor
41 distal upstream DNA over the RNA polymerase zinc-binding domain, NusA rotates underneath one capping
42 zation of the E3 ligase complex, such as the zinc-binding motif and N- and C-terminal regions of the
44 y, these studies reveal a previously unknown zinc-binding site on the surface of the ADAR1 deaminase
46 and Cu(2+) We also demonstrate that multiple zinc-binding sites on tau are involved in the LLPS-promo
47 When combined with a flexible triamine and zinc bis(trifluoromethanesulfonyl)imide, this ketone for
50 tive study on the intermediate states of the zinc-bound native CA II and non-native metal-substituted
54 o provide a fast and simple method to detect zinc, citrate, and aspartate levels as a biomarker signa
56 is used as a surrogate to bind a terpyridine zinc complex (Tpy-Zn), forming a fluorescent [Tpy-Zn]-SP
57 tence, attributed to slower release from the zinc complex and the PLGA NPs, resulted in a 5-fold dose
61 per, lead, manganese, mercury, selenium, and zinc concentrations were measured by inductively coupled
62 i.e., less MIC reduction with higher initial zinc concentrations), while MICs for KPC-harboring isola
65 5% CI: 21, 27 U/L; P < 0.001) and mean serum zinc decreased from baseline (0.75 mug/dL; 95% CI: 0.71,
66 PC alpha-defensin dysfunction is mediated by zinc deficiency and involved in the pathogenesis of AH.
67 and proliferation, yet the mechanisms of how zinc deficiency arrests these processes remain enigmatic
69 12 PSC surveys, the estimated prevalence of zinc deficiency increased with increasing CRP deciles, a
71 ey data, estimates of prevalence of iron and zinc deficiency were comparable but vitamin A deficiency
73 d bidirectional control over the activity of zinc-dependent carbonic anhydrase in solution as an isol
79 tion is a specific and conserved response to zinc depletion in both environmental and pathogenic myco
82 ZnCl(3)(-) detection was validated by total zinc determination using laser ablation inductively coup
86 tion state and local electronic structure of zinc, electrons originating from the zinc oxide excitati
88 h heterozygous variants affecting the fourth zinc finger (ZF4) of Wilms' tumor 1 (WT1) (p.Ser478Thrfs
89 ted that the transcription factor GLI family zinc finger 1 (GLI1) mediates Sulf2 expression during HC
90 of the stem cell-expressed genes GLI family zinc finger 1 (Gli1) or achaete-scute homolog 1 (Ascl1).
91 ce transcription factors, VASCULAR PLANT ONE-ZINC FINGER 1 (OsVOZ1) and OsVOZ2, and promotes their de
92 ese results suggest an active role for GATA3 zinc finger 2 mutants in ER-alpha positive breast tumors
93 memory retrieval-associated increases in BLA zinc finger 268 (zif268) and activity regulated cytoskel
94 g three distinct targeted mutations of A20's zinc finger 7 (ZF7) ubiquitin-binding motif uniformly de
97 ovel RNA-binding protein interactors ZC3H14 (zinc finger CCCH-type containing 14) and THOC1 (THO comp
98 etase Long Chain Family Member 5 (ACSL5) and Zinc Finger DHHC-Type Containing 6 (ZDHHC6), was charact
100 catalytic SET domain and an intervening MYND zinc finger domain, as well as an extended C-terminal do
104 s with CRISPR/Cas9-mediated depletion of the zinc finger E-box binding homeobox 1 (ZEB1) in claudin-l
106 tanding of how a single mutation in the KLF1 zinc finger exerts effects on erythroid physiology in CD
107 n synthesis were detected at lower rates and zinc finger family transcripts were of poorer quality.
109 in Kruppel-associated box domain-containing zinc finger genes on chromosome 19, both of which are as
112 arsenic interacts with the N- and C-terminal zinc finger motifs of GATA-1, causing zinc loss and inhi
114 go, first with meganucleases and followed by zinc finger nucleases, transcriptional activator-like ef
116 rol genes that include homologs of mammalian Zinc finger of the cerebellum and Purkinje cell protein
118 these effects and identify a cluster of KRAB zinc finger protein (KZFP) genes that modifies VM-IAPs i
121 ut ZNF274, a Kruppel-associated box-A-domain zinc finger protein capable of recruiting epigenetic mac
122 that ARS2 (arsenite-resistance protein 2), a zinc finger protein that is essential for early mammalia
123 for awn inhibition in wheat, encodes a C2H2 zinc finger protein with EAR motifs which putatively fun
125 pproaches on two large, independent Cys2His2 zinc finger protein-DNA interaction datasets. We demonst
127 -genome activation, implying that other KRAB-zinc finger proteins (KZNFs) recruit KAP1 prior to blast
129 family of ubiquitously expressed human C2H2 zinc finger proteins comprised of ZFX, ZFY and ZNF711.
130 well as genes coding for aminotransferases, zinc finger proteins, and several uncharacterized protei
132 slocates to the nucleus and interacts with a zinc finger transcription factor (FgZC1), also required
134 er unmask a mutual requirement for Hivep3, a zinc finger transcription factor and adapter protein.
136 otrophin signalling system; a high number of zinc finger transcription factors; and novel factors tha
137 ing only two predicted genes, including C2H2 zinc finger transcriptional repressor TraesCS5A02G542800
138 show that combined biallelic Cebpa and Gata2 zinc finger-1 (ZnF1) mutations cooperatively induce bili
140 Previous studies have suggested that the zinc-finger epithelial-mesenchymal transition transcript
143 ology approach, we identify a new network of zinc-finger proteins that are expressed in one class of
144 introduce three epigenome-editing platforms: zinc-finger proteins, transcriptional activator-like eff
149 Gag or Gag mutants carrying deletions in NC zinc fingers (ZFs) or a nonmyristoylated version of Gag.
151 this geometry are enriched in genomes where zinc fingers are prevalent and specificity transitions w
153 sis likely through replacing zinc within the zinc fingers of the critical transcription factor GATA-1
157 e of DNA fragmentation in the folic acid and zinc group and 27.2% in the placebo group; mean differen
158 ment groups (404 [34%] in the folic acid and zinc group and 416 [35%] in the placebo group; risk diff
160 on to understanding the relationship between zinc homeostasis and the pathogenic process in AD and re
162 ion (Hut) system as being linked to nutrient zinc homeostasis, but whether the Hut system is importan
164 l muscle represents the largest pool of body zinc, however, little is known about muscle zinc homeost
170 efficiency of water-soluble thioglycosylated zinc(II) porphyrins were considerably higher than nonmet
171 metal separately by cysteine and hydrolyzed zinc(II), and synergistically by the combination of the
173 ess was based on the utilization of magnetic zinc-imidazole frameworks (ZIF-4), as a highly efficient
176 ly a valuable tool for analyzing the role of zinc in prostate metabolism but might also provide a fas
177 er, pharmacologically sustained elevation of zinc in WT eggs prior to activation resulted in abnormal
178 distribution of oleic acid-grafted-chitosan-zinc-insulin complexes into the hydrophobic core of PLA-
179 n was significantly improved by formation of zinc-insulin hexamers, further stabilized by electrostat
181 iber and hydrogel doped with the fluorescent zinc ion probe molecule meso-2,6-Dichlorophenyltripyrrin
182 An optical diffuser is incorporated into the zinc ion sensor based on optical fiber and hydrogel dope
185 other members of this enzyme class, a second zinc ion was present in the beta-CASP domain that leads
186 P: a group that interacts with the catalytic zinc ion, functionality that enhances affinity to the su
187 te acts as a counterion for the Lewis acidic zinc ion, which provides the activation of the aldehyde.
189 ed recently; however, both proteins have two zinc ions instead of two iron ions in the catalytic cent
191 mbined with our previous results on divalent zinc ions, we propose a model that links the microscopic
195 ation with a high-affinity modulator such as zinc is most likely to account for the error, and we sug
196 structures, and auditory brainstem, synaptic zinc is released from presynaptic terminals to modulate
203 s of >=30 mug/ml was sufficient to provide a zinc-limited medium, resulting in MICs that reflect in v
204 rminal zinc finger motifs of GATA-1, causing zinc loss and inhibition of DNA and protein binding acti
205 y, we evaluated vitamin D and mineral (iron, zinc, magnesium) transfer to the bolus aqueous phase dur
206 ocopherol (mean: +8.7%; 95% CI: 3.6, 13.7%), zinc (mean: +2.3%; 95% CI: 0.5, 4.2%), thyroglobulin (me
208 nt diastereo- and enantiocontrol followed by zinc-mediated Barbier allylation to set the third chiral
212 aft experiments demonstrate that a synthetic zinc metallochaperone rescues not only mutations that de
214 how rapid antibiotic-mediated evolution of a zinc metalloenzyme obligatorily occurs in the context of
215 are degraded by dihydropyrimidinase (DHP), a zinc metalloenzyme that is upregulated in solid tumors b
216 esses activate the inner membrane-associated zinc metallopeptidase OMA1 that cleaves L-OPA1, causing
217 ciated degradation ubiquitin ligase Hrd1 and zinc metalloprotease Ste24, promote degradation of chara
218 ctivation and presents the first evidence of zinc modulation during egg activation in a non-mammalian
219 s indicate that ZIP9 is essential for proper zinc modulation during zebrafish egg activation and pres
220 odorant responses induced by the endogenous zinc nanoparticles appears to be similar to the amplific
224 ncentration (PZC) is recommended to estimate zinc nutritional status; however, concentrations may dec
225 t and ultraflexible amorphous indium-gallium-zinc oxide (a-IGZO) thin-film transistors (TFTs) and int
226 que, including semiconducting indium-gallium-zinc oxide (IGZO) and copper oxide, as well as conductin
227 nvestigated a sensor structure formed with a Zinc Oxide (ZnO) coating, deposited by Atomic Layer Depo
231 ture of zinc, electrons originating from the zinc oxide excitation and copper plasmonic excitation se
232 ly promote methanol-production at the copper-zinc oxide interfacial perimeter of copper/zinc oxide/al
233 he chitosan films with varying quantities of zinc oxide nanoparticles loaded gallic-acid (ZnO@gal) co
235 surface-micromachined cantilever arrays and zinc oxide surface-microfabricated interdigitated circui
236 transparent conducting oxide (aluminum doped zinc oxide) and pure VO(2) using pulsed laser deposition
237 g a fluorescent mouthguard consisting of the zinc oxide-poly(dimethylsiloxane) (ZnO-PDMS) nanocomposi
242 ate the radiation spectra of superdense iron-zinc plasma mixtures at mass densities of rho = 250 to 2
245 udomonas aeruginosa harbors three paralogous zinc proteases annotated as AmpD, AmpDh2, and AmpDh3, wh
247 artificial protein specifically accumulated zinc protoporphyrin IX, a rare cofactor that is not used
249 atiometric extracellular zinc sensor probing zinc release, supported that Z-LTD is expressed, at leas
255 system utilizes water cooled chromium doped zinc selenide (Cr(2+):ZnSe) as the gain medium and is pu
257 ing studies with a ratiometric extracellular zinc sensor probing zinc release, supported that Z-LTD i
258 requency stimulation induced LTP of synaptic zinc signaling (Z-LTP), evidenced by enhanced zinc-media
261 experience-dependent plasticity of synaptic zinc signaling.SIGNIFICANCE STATEMENT In the neocortex,
262 Finally, we demonstrate that extracellular zinc similarly disrupts early embryonic development in e
264 rom unbinding of the regulator, which, under zinc-starvation conditions, exists in its metal-deficien
265 oduced long leader transcripts (LLTs) in one zinc status condition and short leader transcripts (SLTs
266 , we show that the divalent transition metal zinc strongly promotes this process, shifting the equili
268 TLSB nanocomposite dosage, concentration of zinc subgroup ions, solution pH, adsorption temperature
270 agmentation was observed with folic acid and zinc supplementation (mean of 29.7% for percentage of DN
271 rtility treatment, the use of folic acid and zinc supplementation by male partners, compared with pla
272 ymptoms were more common with folic acid and zinc supplementation compared with placebo (abdominal di
273 ETTING, AND PARTICIPANTS: The Folic Acid and Zinc Supplementation Trial was a multicenter randomized
274 vo results for a digital solid-state cadmium-zinc-telluride SPECT/CT system with in vitro sampling.
276 r different binding times to a solution of a zinc tetraphenylporphyrin (ZnTPP) derivative terminated
277 nded analogue of tetrathiafulvalene (exTTF), zinc tetraphenylporphyrin (ZnTPP), and tetracyanoanthraq
279 tem, glutamatergic nerve terminals corelease zinc to modulate excitatory neurotransmission and sensor
280 p14 (Slc39a14) was the most highly expressed zinc transporter in skeletal muscle of mice in response
282 l ion transporters, such as copper, iron and zinc transporters were upregulated and transferase-encod
283 d depletion of anti-oxidant elements such as zinc, underpin the high incidence of CIN in domestic cat
284 stemic inflammation enhanced Zip14-dependent zinc uptake by muscle, increased expression of Atrogin1
289 (2.5) levels of lead, arsenic, chromium, and zinc were significantly enriched at some locations by fa
290 G was reduced by ~20-fold in the presence of zinc, whereas DVT binding was almost completely lost.
292 nts with lead white (2PbCO(3).Pb(OH)(2)) and zinc white (ZnO) pigments, which are frequently found in
293 bromine fluorescein) lake mixed with lead or zinc white at lower concentrations than elemental X-ray
294 bits erythropoiesis likely through replacing zinc within the zinc fingers of the critical transcripti
297 otianamine (NA) is a natural chelator of Fe, zinc (Zn) and other metals in higher plants and NA-chela