ライフサイエンスコーパス: alpha1beta1 integrin

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1 tatin is a potent and selective inhibitor of alpha1beta1 integrin.

2 QC2, which binds with high affinity to human alpha1beta1 integrin.

3 te recruitment involves the interaction with alpha1beta1 integrin.

4 s partly attributed alpha1(IV)NC1 binding to alpha1beta1-integrin.

5 hages are key orchestrators of inflammation, alpha1beta1 integrin adhesion may represent a mechanism

6 oth muscle cell lines, expressing either the alpha1beta1 integrin alone or both the alpha1beta1 and a

7 Resident CD40(high) DCs express alpha1beta1 integrin and colocalize with collagen in lym

8 burgdorferi strain B31 proteins that bind to alpha1beta1 integrin and hypothesized that, given the pr

9 plex of a chimeric rat/human I domain of the alpha1beta1 integrin and the Fab fragment of humanized A

10 n, competes with type IV collagen binding to alpha1beta1 integrin, and inhibits migration, proliferat

11 decorin interacts with alpha2beta1, but not alpha1beta1 integrin, at a site distinct from the collag

12 ly, these data suggest an essential role for alpha1beta1 integrin/basement membrane interactions in t

13 HUIV26 epitope was associated with a loss of alpha1beta1 integrin binding and the gain of alphavbeta3

14 emonstrate that human alpha1(IV)NC1 binds to alpha1beta1 integrin, competes with type IV collagen bin

15 abetic renal ECM shows diminished binding of alpha1beta1 integrin consistent with the modification of

16 This suggests a highly specific, alpha1beta1 integrin-dependent antiangiogenic activity o

17 In this study the functional importance of alpha1beta1 integrin for retinal pigment epithelial cell

18 Our results showed a dependence on the alpha1beta1 integrin for SPRR3 expression induced by cyc

19 g assay, we show that purified, desialylated alpha1beta1 integrins have diminished collagen-binding c

20 immunostaining with an antibody against the alpha1beta1 integrin heterodimer is present only in bloo

21 were performed to examine the expression of alpha1beta1 integrin in the RPE.

22 These data suggest that in vivo the alpha1beta1 integrin is a critical collagen receptor on

23 The alpha1beta1 integrin is a major collagen receptor that i

24 vascular injury model to illustrate that the alpha1beta1 integrin is the major collagen receptor expr

25 n mesenchymally derived cells in situ is the alpha1beta1 integrin, not the alpha2beta1 integrin.

26 involving cell surface proteoglycans and the alpha1beta1 integrin on endothelial cells.

27 Blockade of alpha1beta1 integrin or genetic deletion (Itga1(-/-)) in

28 cord contusion at T9 in adults, the area of alpha1beta1 integrin positive blood vessels increases wi

29 idneys mediates the selective recruitment of alpha1beta1 integrin-positive monocytes and may potentia

30 at facilitates this selective recruitment of alpha1beta1 integrin-positive monocytes.

31 gainst the binding site in collagen XIII for alpha1beta1 integrin selectively block VLA1-positive mon

32 tending previous results on the relevance of alpha1beta1 integrin to angiogenesis and suggesting nove

33 The alpha1beta1 integrin, very late antigen-1 (VLA-1), is a

34 Our studies show that the collagen binding alpha1beta1 integrin, VLA-1, is expressed by the majorit

35 alpha1beta1-integrin which is required for inhibition of

36 For the interaction of alpha1beta1 integrin with collagen IV, a signal of 10-fo

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